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    <name>A0A0C1H225_9BACT</name>
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    <organism evidence="1 2">
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            <taxon>unclassified Neochlamydia</taxon>
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        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="PATRIC" id="fig|1478174.3.peg.2173"/>
    <dbReference type="Proteomes" id="UP000031320">
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    <dbReference type="InterPro" id="IPR038282">
        <property type="entry name" value="DUF2267_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10025">
        <property type="entry name" value="DUF2267"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="KIC71739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="143" mass="16378" checksum="832769F7B249E557" modified="2015-04-01" version="1">MSVDVFETTLQKTHEWLKDLMGLLGWTDEKKAYLALKGTLQALRDRLSVEVSAKLSAQLPMLVRGFYYEGWKPSIMPVKVKTTEEFLDFVAFHFNSLALVQYSDVEKIVRAVFQVVTQHVSKGEIEHIRQVLPLPIAELWPSS</sequence>
</entry>
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    <accession>A0A0C1H383</accession>
    <name>A0A0C1H383_9BACT</name>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">DB41_AA00200</name>
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    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
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            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244084.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
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    <dbReference type="EnsemblBacteria" id="KIC72039">
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        <property type="gene ID" value="DB41_AA00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2093"/>
    <dbReference type="Proteomes" id="UP000031320">
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="RecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
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    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01447">
        <property type="entry name" value="recD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD_C_2" evidence="1">
        <location>
            <begin position="512"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="582" mass="65838" checksum="5787BC3245B667EA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8K3</accession>
    <name>A0A0C1H8K3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BW00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000243">
        <property type="protein sequence ID" value="KIC71208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71208">
        <property type="protein sequence ID" value="KIC71208"/>
        <property type="gene ID" value="DB41_BW00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="10493" checksum="3E68BB423A6468B1" modified="2015-04-01" version="1">MSMMLYLAIEGIGHSRTKARHPLNPWNRRKIPSGHPERIVCVCHEHIIDVRNYMKDEGKRLLEVALQEEISNHLKLLWSKAKVVSVKEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9X6</accession>
    <name>A0A0C1H9X6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IT00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386062.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000151.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74144">
        <property type="protein sequence ID" value="KIC74144"/>
        <property type="gene ID" value="DB41_IT00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="77" mass="8467" checksum="E65152251C659CAF" modified="2015-04-01" version="1">MLSNEALYVDTSLYSLSPSSPPCPKFSLETLKHPSLIQTLPAALTLSYRVASPGQQAISQVPFMLRFTKSQSTHRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA01</accession>
    <name>A0A0C1HA01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative type III secretion system needle protein SctF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sctF</name>
        <name evidence="2" type="ORF">DB41_AS00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386809.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71663">
        <property type="protein sequence ID" value="KIC71663"/>
        <property type="gene ID" value="DB41_AS00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035365">
        <property type="entry name" value="DUF5407"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17401">
        <property type="entry name" value="DUF5407"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="97" mass="10406" checksum="EED7150EDD22E161" modified="2015-04-01" version="1">MSSNSNQSFPSAPTSYSGANRQSGFEVQSLIGIINNAVSSAKAKLLQIQNNRSSISIGDMFEMQMLMNHLSQLSEMTTDIVSASNTAISSMARNIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA47</accession>
    <name>A0A0C1HA47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AQ00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386775.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000213.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71713">
        <property type="protein sequence ID" value="KIC71713"/>
        <property type="gene ID" value="DB41_AQ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7773" checksum="12D3970C6019DBA6" modified="2015-04-01" version="1">MLYSMLSTYQFPISMLNRLNHRLPLVASLPFLEEYRRINAQLIFLLNLRNRTSYLLSLAATSSLLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAC0</accession>
    <name>A0A0C1HAC0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">bkdB</name>
        <name evidence="7" type="ORF">DB41_IQ00070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386039.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000148.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74304">
        <property type="protein sequence ID" value="KIC74304"/>
        <property type="gene ID" value="DB41_IQ00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1657"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="126"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="408" mass="45451" checksum="661E604A0ED3D7B1" modified="2015-04-01" version="1">MAKIHTVTLPDIGEGVIEGEVVEWLKDIQDTVLQDEAVVIVMTDKATVELPSPYPGKVVKHYYKPGEISIKGKPLYDIELLEGHTAAPPPQFKLKESSLPKPCPLSPLAPSHTDASALAPKSSDVLALPSTRKLAQEMGIDISQIQGTGKAGRVRPEDLRQYVRPSPKENLDTSVLRLEGDKELPIIGIKNLMYQKMVESKRKIPHFSYFEKAEATRLVRLRQKFKEEGAKKNIQVTYMPFLLKALSLTLNKFPQFNSSVDQHKLIIHQQQHIGIAMASPLGLIVPVLKNVQALSLIDLIYAYEELKNKANTNKLQPSEMKEGTITISNFGVLGDGGLWATPIINYPEVAILAVNRIQKQPWACNDNVVLRDVLNLSWSFDHRIIDGDQAAAFSHYYAHLIKNPAPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBG5</accession>
    <name>A0A0C1HBG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386543.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72118">
        <property type="protein sequence ID" value="KIC72118"/>
        <property type="gene ID" value="DB41_KU00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="387" mass="43840" checksum="6E03C2F922B82E0A" modified="2015-04-01" version="1">MRINFDTTHIKKFLDDSSEKYVVTLNENSQRFVPLRQTSIFHRIAAWFGCGPLSLNNIANFISHHNEKINQKLTPANQILFYQKLIGKCLHYNSNYIHAFSHVPNSVLSAFEKHVPMCSDAFFSKETTYHSREDGLDGNVDFSYSNRRLGFGYVVDGAGHNNPYMQPVLQELLRKFTQSYEQALESRKFKTIESAQQFLTDQLGQLARTLTSDSRPIHKNSSTFEDPSYHPAISFAQTIKIGSSYYLLSVELADTMIVIKKANGTFDTSLAISRPDFGLGSGTINVHTTPISPGDTIIGFSDGIGEYLTLEECTEIISSSMPSNLLENFKDKIIDKGKEFTKRVSDTSMRREEDIQSANQSRYIKYHTFDVASPRYHDDISLFALTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBU5</accession>
    <name>A0A0C1HBU5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">murI</name>
        <name evidence="8" type="ORF">DB41_KP00100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386462.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000195.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72278">
        <property type="protein sequence ID" value="KIC72278"/>
        <property type="gene ID" value="DB41_KP00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2003"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="43"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="186"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="271" mass="30300" checksum="F30B5E1C62B41452" modified="2015-04-01" version="1">MSNSQAIGIFDSGIGGLTVMKQIMHKLPHEKLIYFGDSARLPYGDKSADTILRYSIENAIFLMEHQIKLLVIACNTASAYAVDKLKQILKIPIVDVIQPGVEHAAKASRHLRIGVLATRATTESGIYPQQIKKKLPSCQVYSMPCPLLVPLIEEHLFDHPATQLIIKDYLAPLKQSSIDTLLLGCTHYPLLRPLIQKEIGPHVCIVDSASTCAEHVSLTLDTYNLHACPDEKPSHRFYVSDYPEKFRLHGSKFLGHPIDKVNIPLKMKFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCK4</accession>
    <name>A0A0C1HCK4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HV00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75134">
        <property type="protein sequence ID" value="KIC75134"/>
        <property type="gene ID" value="DB41_HV00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1349"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="136" mass="15463" checksum="9DCD02C8C5B60C91" modified="2015-04-01" version="1">MKIREESIQMGEIFKQRRKELNLSLKEIENATSIRISHLQAIEEGEIDKLNSPVYAQGFIRQYAAFLGIDGEKIVRENPAIFSRPEAQEFAYGIGTLEVRGNPGAGVKWFPNAIWISAFILLIITAWFTARYFGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD98</accession>
    <name>A0A0C1HD98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HN00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385361.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75384">
        <property type="protein sequence ID" value="KIC75384"/>
        <property type="gene ID" value="DB41_HN00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="450" mass="50496" checksum="E7BECCDDF3F63764" modified="2015-04-01" version="1">MQPDYASKAKQDLTNQLRVFTPVMNDRAGESLPSTSLPEQVIEAKVIMIGETHGEAAEEIGKLVNALASQYLSEKEGKIKLLVEGDVEKRAKYIASLPSAYRDHIQISSWDTDLSKEVLNSFFNQVVSRFHANVCQAFMNYLSNPSTENRKTIMDILRRLTFAQIPGWMEKESPPSLRPSIEGYLDDLKPHLIDLQSHADQKEETLGFLSSLNFYLETFYRMVKEITIQATPQRNMKMVENIQTSLSSADKVIVIAGKSHLFGPDTFSERERLSIKEGIQIMEESLSQQQTSYIILNAPSPFDTTAETDDLIKPQSIPPEWLEEPIVSEKGKQKEQEKDEPKPQPSSVSGASSPSLSPTGDVSWREKLQASKAKASATSSQDAIRQALKFNIEKLKTVNDRESLALQFKGSFKAIWGEIMRKHSIAMEDDVILADLLTITVEKLIELKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDX4</accession>
    <name>A0A0C1HDX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JX00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000180">
        <property type="protein sequence ID" value="KIC72958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72958">
        <property type="protein sequence ID" value="KIC72958"/>
        <property type="gene ID" value="DB41_JX00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8602" checksum="C22ED06AAE269F8E" modified="2015-04-01" version="1">MTGRNWWIVFHHSVEELKQGTKKSRFISNTKNQFHFFSQTQIAASLNRQNLWLLLNAWKALPFLNLSEIKAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEC3</accession>
    <name>A0A0C1HEC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HF00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385137.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000116.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75779">
        <property type="protein sequence ID" value="KIC75779"/>
        <property type="gene ID" value="DB41_HF00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019291">
        <property type="entry name" value="Host_attachment_protein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10116">
        <property type="entry name" value="Host_attach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="145" mass="16516" checksum="03117B5FD870790D" modified="2015-04-01" version="1">MPHTLTWIVVANSSKAKIYRLAKFPKIEELLVLNHPESRLQDQVLEGRKPGRNFQSGGTTRHAYEPETDPKEVEKEKFARSLGDYICAAHYKGEFTRLYLMANPAFLGLVRHHINTSTQKTIVAEVAKDLTDCPIPEIEHHLVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEH8</accession>
    <name>A0A0C1HEH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75839">
        <property type="protein sequence ID" value="KIC75839"/>
        <property type="gene ID" value="DB41_GZ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5573" checksum="C7A84865BD886C80" modified="2015-04-01" version="1">MATALVLQAAYNQTSFNFSQFDYRFLQGKNYYKIITLSNLAQQDLFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEK1</accession>
    <name>A0A0C1HEK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YdiC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ydiC</name>
        <name evidence="2" type="ORF">DB41_GZ00330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384981.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75869">
        <property type="protein sequence ID" value="KIC75869"/>
        <property type="gene ID" value="DB41_GZ00330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1098"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="35"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="228" mass="25579" checksum="DCFA7A06BF9F898A" modified="2015-04-01" version="1">MFSLVIDTSSERGCAAFFDGREVIFQGNFPFGLNSSQSLLPEIERGLKYLGRKAADLSYVAVGIGPGSYTGIRVGVVVAKAVAFSLRKPLVTFCSLEGFLPSHEGSYAVLFDAKIGGVYVLKGQASRGAYEREGKVQLLPLSEVGVYLQNVNNLLTPNSLLLKQKIENMYPNWQWTWEEKGPDALYLSRLSEDKWRRGEIMQKEPLEILYLRKTQAEIEKELQKSIQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEM1</accession>
    <name>A0A0C1HEM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative voltage-gated potassium channel subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kab1</name>
        <name evidence="2" type="ORF">DB41_JQ00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386190.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73153">
        <property type="protein sequence ID" value="KIC73153"/>
        <property type="gene ID" value="DB41_JQ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1801"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0407">Ion channel</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="343" mass="38437" checksum="D3EDC87B053BB29D" modified="2015-04-01" version="1">MEYRQLGKSGLQVPVLSFGTATFGGANEFFKPWGETDVKEATRLVELCLDKGLNLFDTADVYSQGRSEEILGQALKGKREKVLISTKATFQMGEGPNDQGSSRFHLIKACEASLKRLGTDHIDIYFMHAFDALTPVEETLGALDHLIQSGKIRYIGCSNFSGWHVMKSLAVSEKYGLARYVVYQGYYSLIGRDYEEELMPLGVDQGIGLMAWSPLGWGRLTGKIRRGMPLPEGRLKSGGDIGGPQVDDEFLYDVLDVLEEVAQETEKTVPQVAINWLLQRPTVANIVLGARNEEQLKQNLGSIGWNLTQEQVAKLDKVSERMPSYPYWHQRFSRERNPSPLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HER5</accession>
    <name>A0A0C1HER5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_JN00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000170">
        <property type="protein sequence ID" value="KIC73193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244029.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000170.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73193">
        <property type="protein sequence ID" value="KIC73193"/>
        <property type="gene ID" value="DB41_JN00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1796"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="121"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="331"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="373"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="415"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="457"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="499"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="541"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="625"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="667"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="730" mass="82272" checksum="275D8C26DAD478C6" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGG8</accession>
    <name>A0A0C1HGG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyrophosphate--fructose 6-phosphate 1-phosphotransferase</fullName>
            <ecNumber evidence="9">2.7.1.90</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-phosphofructokinase, pyrophosphate dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PPi-dependent phosphofructokinase</fullName>
            <shortName evidence="9">PPi-PFK</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-dependent 6-phosphofructose-1-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pfp-BETA1</name>
        <name evidence="9" type="synonym">pfp</name>
        <name evidence="11" type="ORF">DB41_GC00210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Non-allosteric.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.90" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384525.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76454">
        <property type="protein sequence ID" value="KIC76454"/>
        <property type="gene ID" value="DB41_GC00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.851"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01980">
        <property type="entry name" value="Phosphofructokinase_II_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011183">
        <property type="entry name" value="PfpB_PPi_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005677">
        <property type="entry name" value="PPi_PFK_PfpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02477">
        <property type="entry name" value="PFKA_PPi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="10">
        <location>
            <begin position="68"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="198"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with dimeric partner" evidence="9">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="245"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="423"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP" evidence="9">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi" evidence="9">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="548" mass="60982" checksum="C9C300B60BE20316" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGJ7</accession>
    <name>A0A0C1HGJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GB00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243869.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000087.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76474">
        <property type="protein sequence ID" value="KIC76474"/>
        <property type="gene ID" value="DB41_GB00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.826"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="450" mass="51472" checksum="44007F98A133513C" modified="2015-04-01" version="1">MNYSSSISMKHLPNEVLTSILEYCPRPALLRVCIRWRHLLATEVMPSLYKQIGKTHVPQGDISEQAIILDKLYKLEAELPEVEKVKAIFKQIFTLASTLSPLEFKSETEEKKYFTLSNYSSYLININRLLIWNKISGGKEYLDQEEIKYLPLEKKGGLFRDWIERHSKDITSLNLTEIGLTFLPPEIEQLSHLQELKVNDNQLTSVPIKIEHLSQLQMLDLDDNQLNFLPVKIGQLSQLQMLYLNRNQLASLPAEIGQLAKLQWLHLHNNQLTCLPAEIGQLSQLQMLYLNHNQLISLPIKIGQLFQLQELYLDGNQLTYLPAEIGQLSQLQWLYLDDNQLTTLPAELGQLSQLQILYLNNNQLTCLPAEIGQLSQLRRLGLSSNQLNSLPAEIGQLSQLQDLDLNNNQLTCLPAELGQLNALQRLNLENNQLTTLPAEIENLLALSRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGM0</accession>
    <name>A0A0C1HGM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonuclease G</fullName>
            <ecNumber evidence="7">3.1.26.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rng</name>
        <name evidence="7" type="ORF">DB41_IY00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.-" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386082.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73813">
        <property type="protein sequence ID" value="KIC73813"/>
        <property type="gene ID" value="DB41_IY00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1702"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="38"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC73813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="512" mass="59772" checksum="62BD9CFFFE86AAFD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHF5</accession>
    <name>A0A0C1HHF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="primary">ribF</name>
        <name evidence="13" type="ORF">DB41_EO00020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383886.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76749">
        <property type="protein sequence ID" value="KIC76749"/>
        <property type="gene ID" value="DB41_EO00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.534"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="182"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="305" mass="34342" checksum="3F6922CB7576ACF1" modified="2015-04-01" version="1">MKLIHELPSTSLFSTSSVLTLGNFDGMHIGHQTIIKKVVETAKKQHQASVVLSFENHPSEVLYPDRPVNKICTNEHKIQLIKNMGVDLLILLKFTKEFSEQSAEQFIHHLQTLLPFSHLILGWDATLGKDRKGNKETIKGIAEREHFSVEYIEQQTVNEVAVSSSLIRKFIQEGRLETAQKLLGRPYSVLSTVYRGLGKGKQLDCPTANLDVKNLCIPPLGVYAVNIFVDQQLFKGVANLGIAPTVREDKVPLLEAHIFDYEADLYGKTIEVILTSYLRPEKKFASLEELKLQIQQDILKARSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHH8</accession>
    <name>A0A0C1HHH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF294_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EL00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000051">
        <property type="protein sequence ID" value="KIC76769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76769">
        <property type="protein sequence ID" value="KIC76769"/>
        <property type="gene ID" value="DB41_EL00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF294_C" evidence="1">
        <location>
            <begin position="213"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="369" mass="42786" checksum="1EFA754EED4E69E9" modified="2015-04-01" version="1" fragment="single">MIGFGSLAREEMTPYSDLEFGILVQDDNPINKKYFRNLTNLLHLKIINLGETILPALNIPCLKAIDFFDGITPRGFAFDGAGVEGKGCKTPLGNGKTFELIQTPEQMAQYLGKDEKGQWWHKKDPHLPIELLNFTHLLGNFELTKAYDENIQEVLNMSYQENLDLRQYLAKQHLVPADMEAFNPRMSDLERQGMLFKVKNDFYRFPHLALDRLALLKKVAATNTFTRIDKLSELKIITKEATERLKEWMSLVLFMRLKTYSHYQAQQEMMNPLLKPFGFEDPGLIKKQFALDHTTLKLIKKIYRIFIPFHQSIHEFLAGNEDILKSSDLEDNSPETRGDIHQRLFQHKKAEKWYLLAEQENPQNAGILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHM8</accession>
    <name>A0A0C1HHM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
            <ecNumber evidence="8">4.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase</fullName>
            <shortName evidence="8">(3R)-hydroxymyristoyl-ACP dehydrase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-hydroxyacyl-ACP dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">fabZ</name>
        <name evidence="9" type="ORF">DB41_EH00030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the thioester dehydratase family. FabZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383779.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76819">
        <property type="protein sequence ID" value="KIC76819"/>
        <property type="gene ID" value="DB41_EH00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.470"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="8">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="155" mass="17095" checksum="69862BE4F6F20D3F" modified="2015-04-01" version="1">MEVHVADYPKSLDIKQIAEILPHRFPFLLVDRVLDINLEQGLIVGQKNLTFNEAFFQGHFPDTPIMPGVLMVEALAQLGGILIHMKGYHDKIAVLLTVNNAKFRNPAKPGDVLMLKVEGIHVSSKAGRMQATATVNDKITAEAEIGFALVDKNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHS3</accession>
    <name>A0A0C1HHS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76859">
        <property type="protein sequence ID" value="KIC76859"/>
        <property type="gene ID" value="DB41_EC00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="8088" checksum="8E63CCEA407797BE" modified="2015-04-01" version="1">MKVQDSLYVWIEGNEDKKERSALKSLQKRHIIRIGSSLHSNLFTCLILKEPNISTKRERMATLAFKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIM4</accession>
    <name>A0A0C1HIM4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mrp</name>
        <name evidence="7" type="ORF">DB41_IP00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74408">
        <property type="protein sequence ID" value="KIC74408"/>
        <property type="gene ID" value="DB41_IP00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1639"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBBH-like_N" evidence="6">
        <location>
            <begin position="281"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="371" mass="41059" checksum="BF73998BFA2AA796" modified="2015-04-01" version="1">MPLPMFPATSKASANFVHAIIGIAAGKGGVGKSCVTVNLARALKDLGFKVGILDADIYGPSIRRMLPEDKMPEQCNERILPAICQGVKVISMAYFRREDEAAAIRAPIANTIVQQFIKNVDWGEIDFLLIDFPPGTGDIQLTLSQNAQLNAAILVTTPQEVALMDVRKAMDLFYQMKIPIIGVIENMSYYQISPNLKRVYPLGQGGGGRLAKEAGFSLLGQIPISSEISHSGDKGNSLFEEKTPDAQAISKIFINLAKKVMEQLVEIKKRETAEVEKFFQKDPATFTLQWSDGLMADFYLSDLQRRCPCAGCIEKSVENKAGDKKTNRDELRVSTIERVGHYALRIYFTSGCNQGIYTFSFLRQMAQEQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ34</accession>
    <name>A0A0C1HJ34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CK00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77279">
        <property type="protein sequence ID" value="KIC77279"/>
        <property type="gene ID" value="DB41_CK00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4876" checksum="928700013CA123E4" modified="2015-04-01" version="1">MLSYPERPELLERYLLLFEINHGWSTNKAKEEALFCIEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ44</accession>
    <name>A0A0C1HJ44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rpsD</name>
        <name evidence="10" type="ORF">DB41_CK00170</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383067.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77289">
        <property type="protein sequence ID" value="KIC77289"/>
        <property type="gene ID" value="DB41_CK00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.31"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="9">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="8">
        <location>
            <begin position="93"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="23486" checksum="A40CC1798E2E5C31" modified="2015-04-01" version="1">MARYTGNKNRVARRFGANIFGRTRNPLLHKPNPPGMHGARRRKKSDYGLQLEEKQKLKAIYGMLSEKQLVAYYKHAFNMAGNTAQHFAELLECRLDTIVYRLKLASTIFAAHQLVSHGHILVDGKKVDRRSFQVRPGMVITVKEKSRSMKAIQQSLDNPSRSVPDYLSFDKENSGGQLLAMPTPEQMPWPIEIKLHEICDFLAHST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKA5</accession>
    <name>A0A0C1HKA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal large subunit pseudouridine synthase C</fullName>
            <ecNumber evidence="3">5.4.99.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rluC</name>
        <name evidence="3" type="ORF">DB41_IB00560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.24" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385738.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74923">
        <property type="protein sequence ID" value="KIC74923"/>
        <property type="gene ID" value="DB41_IB00560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="2">
        <location>
            <begin position="89"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="291" mass="32990" checksum="7C37D0ED01A838DE" modified="2015-04-01" version="1">MQWMVDTAESGQKLVNFLKGKLGSSYSARQIKSSIEYKGCYVNHRLEHFASTVLAKGDKVSLPAGILEKKPLSSFQFLPSQIIYEDKELLVYNKPAGVASDGQVLTEALKAYNVRWELLHRLDRDTTGLLMFTQGKVFREKMVAAFKKQEIDKVYLALIDGITRQEAGNINNYLGKLHDYLGQSLWGAVPSAEGHHALTAWKVQKKGPKASLVHCYPRTGRTHQIRVHMSEMGHPILGDRQYGKLFHCSYHSPRCLLHAYELSFIHPTLLRKMHFQAPIPLDFQQAMAQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLM6</accession>
    <name>A0A0C1HLM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Single-stranded DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ORF">DB41_HS00060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385432.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000129.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75308">
        <property type="protein sequence ID" value="KIC75308"/>
        <property type="gene ID" value="DB41_HS00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1332"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="172" mass="18869" checksum="8EC6B2CB54860CF1" modified="2015-04-01" version="1">MIIIEIAGHLGTDPEVRFTPGGQKVTMLRLATNTRKSGKDETVWWRVTIWGERFDKMMPYIKKGSALIVIGEMGKPEIYTDKEGRPQVSLDLTAEMIRFSPFGKADRAGQEPSGQASYGQASTPSSYNSPSAYSEPSYTSQSTGNTGYSSYPGNQSSYKPAPNVPDDDNIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQP9</accession>
    <name>A0A0C1HQP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FX00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384393.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76503">
        <property type="protein sequence ID" value="KIC76503"/>
        <property type="gene ID" value="DB41_FX00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="461" mass="50865" checksum="D328A1877EA53984" modified="2015-04-01" version="1">MATSVTKSKFFSIDASPANWALHKAVLSEAGKYRLAARSWVFVSTISCVPSAGQQLANLIIKMAAATYITTLGQIPALKKRSWSKLESCNLISENLSKSWMNVALHAYKFVMFLTISPICCLITGIVSPKTCKDIHDKLHLTGPQQSQADLNKSPSDPTSLPSSQAVESLPAAKKAALSTDTQSRPLPAIPGNGVPPPPPLPPNTFINSSNIEEEKDVEDLLDLILAMKLKSVTPQEDGEHSEAENDILLQTLGSAFNQMANKLSNEPGSINSSARNSVNLDEWRDSPSHSARNSTMYAQESLLMGIEREKLAEEELLQRLESVKNNDEHVESQIPAQGDIKKEEQALEDKREKDKEQEKTLSMEDIHQKIKRRRRALETFNTLTAAQQSLIRTKLNPNQKNILNKLVELPPESKATQEPQHGSMANKSTKTAVEANNPAASKSNKRRRRRNAAKKNVKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQZ3</accession>
    <name>A0A0C1HQZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FM00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384275.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76573">
        <property type="protein sequence ID" value="KIC76573"/>
        <property type="gene ID" value="DB41_FM00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025640">
        <property type="entry name" value="GYF_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14237">
        <property type="entry name" value="GYF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="GYF_2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="112" mass="13875" checksum="54C487FBE2A7A131" modified="2015-04-01" version="1">MDKKEWFIKIDNQKEGPFSISELKIHPHLTPDTWVRKIEWQDWLPARQVPELKVLFEDHHSEELRDKFKSNKPQVQEDSTLLLEKPQPPFFIYWLIVLLFLFLYFFYQFYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRE6</accession>
    <name>A0A0C1HRE6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LPG_synthase_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_EY00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383977.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76698">
        <property type="protein sequence ID" value="KIC76698"/>
        <property type="gene ID" value="DB41_EY00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="LPG_synthase_C" evidence="7">
        <location>
            <begin position="31"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="332" mass="38037" checksum="F42D657DA03995C6" modified="2015-04-01" version="1">MQLQELPSQQKLSSQEIADYVTRWGGSPSIALLDPRCQIFTSRYAEGLIGYRLAAGAAVVFGEPVCDPALKVSLALEFEEHCKSHKKNIVYTQVSQEFGDWGVRHYNGALIEVGHDFFVDPHLDPTARRDARMLRKKVKHALTEGTSIHEYTSPQAELEQAMEQAKQTWLKGRKGPQIYLSNIHLFNNRSGKRWFYAIKGNRLVGQCMLNQLEARGGWVINLLMATPEASGGTTELLVVSILEQLRKENCQYLTFGMVPLDKIDRITGLSTFSNWFTKTAFKGANWMFKLDGKRKYWQKYKPYYESSHLLFTNKKFMARDMFGLMRAMNARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRR1</accession>
    <name>A0A0C1HRR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EI00280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76813">
        <property type="protein sequence ID" value="KIC76813"/>
        <property type="gene ID" value="DB41_EI00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4666" checksum="EFB8666C0FABD496" modified="2015-04-01" version="1">MLRAGSNKEIQVAFLLSCRKSLKGVRGELFIAYYPYKTAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSV5</accession>
    <name>A0A0C1HSV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DA00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000017">
        <property type="protein sequence ID" value="KIC77118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243758.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77118">
        <property type="protein sequence ID" value="KIC77118"/>
        <property type="gene ID" value="DB41_DA00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.190"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="160" mass="17952" checksum="9B126C0ADD326085" modified="2015-04-01" version="1">MLGLNQNQLTSLPAEIGQLSELQTLELRENQLTSLPTEIGQLSELTRLYLKQNQLIALPVEIGQLSQLKTLELNQNLLTNLPAEIGQLSELQWLNLNQNQLSSLPVEIGQLSQLQELGLNQNQLTNLPAEIGQLSQLTKLELADNPLKDIAEEIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSW1</accession>
    <name>A0A0C1HSW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CZ00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77128">
        <property type="protein sequence ID" value="KIC77128"/>
        <property type="gene ID" value="DB41_CZ00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5473" checksum="DA49888A9A4B3355" modified="2015-04-01" version="1">MKKKANADKILKAFGIDNIHHLFYSATKNVGRKELQKMLTEAIEDELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JIG1</accession>
    <name>A0A0C1JIG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CB00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000247">
        <property type="protein sequence ID" value="KIC71180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039387071.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000247.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71180">
        <property type="protein sequence ID" value="KIC71180"/>
        <property type="gene ID" value="DB41_CB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012872">
        <property type="entry name" value="DUF1670"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07900">
        <property type="entry name" value="DUF1670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="280" mass="31908" checksum="49F05C86D54DF728" modified="2015-04-01" version="1" fragment="single">MKKNIDANHATFCPQAFKCFEGALEAFFSHECPQLGGTRTRQVLVKSIADMVRQFYPQTSHMQPGQVTWPTVHRDEFSSYGKSIQNTRLTTVILDLVSSQDAIERAKGKKLRVIKKEAVARMCKQAFDQEGCLTHAELAILLKISPHSVGKYIKEWELENREVLPRRGSIHDIGPTLTHKTIIIEKLFIEQKTVQQVSRETKHSLPAIQRYISTFKQILLCKQKGMSTEEAAFSVGKTSRLVNEYEKIIEQYKEKNYVIAALLKSEIGIETRTQITINEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJQ3</accession>
    <name>A0A0C1JJQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_AV00050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386877.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71565">
        <property type="protein sequence ID" value="KIC71565"/>
        <property type="gene ID" value="DB41_AV00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2241"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="770"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="825" mass="88481" checksum="E2BD5BBB810D0190" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKH9</accession>
    <name>A0A0C1JKH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="7">TC-AMP synthase</shortName>
            <ecNumber evidence="4 7">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ywlC</name>
        <name evidence="10" type="ORF">DB41_AI00020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="4 7"/>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386713.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71795">
        <property type="protein sequence ID" value="KIC71795"/>
        <property type="gene ID" value="DB41_AI00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2157"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="9">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR004930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC71795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="315" mass="34926" checksum="28D1C95C052F1D24" modified="2015-04-01" version="1">MRISLKEAAHRLNTGEVVGVPTETVYGLAASLNHLQAIEHIYTLKGRPSNNPLIIHVAELNEVLSYQQGNISDLEILAQVFWPGPMTIVLPVKCRLIPAKARANLPTAAFRIPRHPLALELLKQTGPLVMPSANLSGSPSSTRIEHVEHDFGKAFPVLDGGTCQKGLESTILTYRNGYWQIIRQGALTAEDFCSSLGYLPMFQQQNSEKPLCPGGMYRHYAPQAKLKLVQSFKNIVEGVIIGFSDRHYPAGCKVFALGPLAEPELAASNLYAVLRQLDQEKYREAYVDVNFLKRGILATLSERLHRASEKPSEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLR1</accession>
    <name>A0A0C1JLR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AY00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000220">
        <property type="protein sequence ID" value="KIC71501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71501">
        <property type="protein sequence ID" value="KIC71501"/>
        <property type="gene ID" value="DB41_AY00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="95" mass="11504" checksum="73825CFB21FAC09C" modified="2015-04-01" version="1" fragment="single">MNYLCRHVSVHQDLGFQWKMRHMKIHNCQVEYHWLVDGQRVVSLWFCCQSVALYSPTSITPFGHKPMDNTEWYMTSNCQLLLIMQYSCYQFIIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLY5</accession>
    <name>A0A0C1JLY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71561">
        <property type="protein sequence ID" value="KIC71561"/>
        <property type="gene ID" value="DB41_AV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4797" checksum="2D184188A036AA34" modified="2015-04-01" version="1" fragment="single">MRGKKSLSCQEFFEAYKGWNQEIFIRGDKINGVQAGGARLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMH1</accession>
    <name>A0A0C1JMH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KK00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244053.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72475">
        <property type="protein sequence ID" value="KIC72475"/>
        <property type="gene ID" value="DB41_KK00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1935"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="198" mass="22420" checksum="1D5DCC798C1C8855" modified="2015-04-01" version="1">MTYLPSEIKQLSQLLNLYLNQNQLSSLPGEIGQLSQLRVLYLNRNQLTALPIEIGQLSQLQVLDLNQNQLTSLPGEIGQLFQLQRLKLIQNQLTSLPAEIGQMSQLKELDLNQNQLTSLPAEIGQMSQLKELDLNQNQLTSLPGEIGQLSQLKKLYLNQNQLTSLPAEIGQMSQLTKLELAENPLKDIVEKIRQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMI3</accession>
    <name>A0A0C1JMI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244055.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72485">
        <property type="protein sequence ID" value="KIC72485"/>
        <property type="gene ID" value="DB41_KK00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="227" mass="26473" checksum="B3C5DBA1B6EAF30F" modified="2015-04-01" version="1">MHWIDDYQLFLFDFDGLLVNTEEIHFKAYQYMCKKYGFNLDWSFARYCQAAHYHAEGLKEEIYRELPALYEVEPNWDVLYACKREKVIELLHQDIQLMPGVQELLEALNKANIKRCVVTHSPQALVDTVRCQLPILNTIPYWFTREFYTHPKPHPESYLTAIKQLADYQDNIIGFEDTPRGIKALLQTSAQPVLVSKAAYDNLPSNVIRVVDFNVLNNSQKLESLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMI9</accession>
    <name>A0A0C1JMI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72490">
        <property type="protein sequence ID" value="KIC72490"/>
        <property type="gene ID" value="DB41_KK00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1951"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="612" mass="71547" checksum="A7706A76E9BD2222" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN23</accession>
    <name>A0A0C1JN23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AD00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000204">
        <property type="protein sequence ID" value="KIC71966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386629.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000204.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71966">
        <property type="protein sequence ID" value="KIC71966"/>
        <property type="gene ID" value="DB41_AD00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2114"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="746"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="582"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="987" mass="112610" checksum="1D484ECE3655D7E8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN64</accession>
    <name>A0A0C1JN64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AB00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000202">
        <property type="protein sequence ID" value="KIC71996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71996">
        <property type="protein sequence ID" value="KIC71996"/>
        <property type="gene ID" value="DB41_AB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="261" mass="29438" checksum="D2064339158F21B5" modified="2015-04-01" version="1" fragment="single">MHPISSASIGSLPNELLLPILEACAAPPLFSVCKRWHHLLASEVMPSLYRKIAQLHFPRGNATTQQTLMLAKVYQLNPVLTSTEKVYQVFKQVFTLAKSISPLEFKWKTEEKKYFTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEEKGELLRDWIEENCKNTTALDLSGVGLTYLPSEICQLSRLQGLKLSQNQLTSLPGEIGQLSELQALNLNQNQLTSLPVEIEQLSQLGELNLNQNQLTSLPAEIGQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNA3</accession>
    <name>A0A0C1JNA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="4">GluTR</shortName>
            <ecNumber evidence="4">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">hemA</name>
        <name evidence="7" type="ORF">DB41_KD00150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="4">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386299.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72715">
        <property type="protein sequence ID" value="KIC72715"/>
        <property type="gene ID" value="DB41_KD00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1873"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="6">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="5">
        <location>
            <begin position="169"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="46"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="183"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="4">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="342" mass="39377" checksum="9CC6F909099AA2F5" modified="2015-04-01" version="1">MRIGVLGINYKLADLKLRELLAKACQKRLGAGTSMHGHHHFILLSTCNRTEIYFCSDDLADTHTYLLNIFRNEVDMQFDQKLYSYFGHDCFYHLSRVTAGLDSAIVAETEIQSQVKHAYKISCQFSQLPEDMHYLFQKALKIAKKIRSQHLLTRALPDIEHAVFNTGSHFFKNLSQAKILLVGASAINQKILRFLMSKNFTDITICNRTKKHAIDLARTYQLNLLEWQSLAQWHQFDWIICGTKAPQALISYSHLPLKEIPAKLLIDLGVPRNIDPSIARHAKITLLNIDQINRMLTFRKQKLYEHLTKADHGIIEATKQHIHLFKQKQTYREQLLAVGMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQV3</accession>
    <name>A0A0C1JQV3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH_17 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JG00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EUO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386129.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73570">
        <property type="protein sequence ID" value="KIC73570"/>
        <property type="gene ID" value="DB41_JG00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1740"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="2">
        <location>
            <begin position="86"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="17727" checksum="0DEAFC1D81FB06B0" modified="2015-04-01" version="1">MVTQSFHLPEPIMPSESEVELARASSRILSSMDLQKGKTVKILLETDNYQQSSVTLPFSAFKLLMTVLTQMAEGNAITLIPVHAELTTQEAADLLNVSRPYLIRLLEEKKIPFRKVGTRRRILFQDLMDYKAKIDAARRKTLDELAEEAQNLDMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTF5</accession>
    <name>A0A0C1JTF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_7</name>
        <name evidence="3" type="ORF">DB41_IZ00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000157">
        <property type="protein sequence ID" value="KIC73736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244012.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000157.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73736">
        <property type="protein sequence ID" value="KIC73736"/>
        <property type="gene ID" value="DB41_IZ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1710"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="540" mass="61406" checksum="28E62D9B497B1EFD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTW9</accession>
    <name>A0A0C1JTW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74550">
        <property type="protein sequence ID" value="KIC74550"/>
        <property type="gene ID" value="DB41_IJ00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="5776" checksum="8A181151B2E50B1C" modified="2015-04-01" version="1">MINGERLAIDGFFSRGKGDGKLVDYGHKGKDKPTHLLVDDNGSPLSFEATNAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV39</accession>
    <name>A0A0C1JV39_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">ctaB</name>
        <name evidence="9" type="ORF">DB41_IB00680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74935">
        <property type="protein sequence ID" value="KIC74935"/>
        <property type="gene ID" value="DB41_IB00680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1503"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="283" mass="31571" checksum="08BC9BD89BA7A5C1" modified="2015-04-01" version="1">MIIKTYYMLTKPGIIAGNAVTTFGGFMLASKGAVNFWLFCWTLMGLSLVIASACVFNNYMDREIDKKMARTKNRALVKGLVSEKNALLFGTLLGLLGMGVLALYANFLTAMLALAGFLFYVVVYGVWKYRSSYGTVIGSLAGGVPPVVGYCAASNQLDLGAFLLFTIMVLWQMPHFFAITLYRLEDYAAASIPVLPLEKGIYTTKIQMWLYIIAFIVATVMLTLMGYTGYAYLTVAVLMGLMWYVLCLKGFKSDNDKRWARQMFLFSIVVIMVECFMMAIDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVB7</accession>
    <name>A0A0C1JVB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BW00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000243">
        <property type="protein sequence ID" value="KIC71207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71207">
        <property type="protein sequence ID" value="KIC71207"/>
        <property type="gene ID" value="DB41_BW00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="10251" checksum="AAC1DDA4FE0A5B0D" modified="2015-04-01" version="1">MIWVLIQADYRDRLIQSLRLFKNVLKVSEAKVAQEEMILTENQLKALEKPRKKKKCMEKLKLNIQVIYYLKDTYYVGTIKGVGRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVI5</accession>
    <name>A0A0C1JVI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74416">
        <property type="protein sequence ID" value="KIC74416"/>
        <property type="gene ID" value="DB41_IP00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5500" checksum="13211AF80386490F" modified="2015-04-01" version="1">MLRKILRRAQEGQMINGFNHQYAEDSGNGVNFWALLLPLNLYFSFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWM8</accession>
    <name>A0A0C1JWM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AU00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71627">
        <property type="protein sequence ID" value="KIC71627"/>
        <property type="gene ID" value="DB41_AU00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="158" mass="17505" checksum="69FBAF9D35882BAD" modified="2015-04-01" version="1">MFNLSSTLLMSQRKKFMQGAGSTPPSPPLENMPVVSAFKTRTTETSQTEEQQPQREEGQSTSLPPSASQLERIQQANLNQSAQQSRLLSLAKKRKSETSQIEEQQSQREEGQSASSASRVLPLQQDPSNELIFLWCFFITMGSKSALRSLGTCKLIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWP9</accession>
    <name>A0A0C1JWP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lpxD</name>
        <name evidence="8" type="ORF">DB41_HK00030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000121">
        <property type="protein sequence ID" value="KIC75510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385311.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000121.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75510">
        <property type="protein sequence ID" value="KIC75510"/>
        <property type="gene ID" value="DB41_HK00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1254"/>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="7">
        <location>
            <begin position="25"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="352" mass="38118" checksum="BD76812E859205EB" modified="2015-04-01" version="1">MNSLKTFKLAHIAAMTQSKLIGNPDYEIEGVADLERASAKEASFLENPRYEQAMQKSHAGVIFVNSHTPLAGDRNFLINENPSLAFQQLIDAFFKEKEELTGFAGIHLTAVIHETCQIGANVKIGPHAVIDKEAKIDDNTFIGAGVYVGPYVTIGKDCLIHPKAVIRERCSLGDRVILQPGAVIGACGFGYITNKAGEHIKLQQLGKVEIEDDVEIGANTTIDRSRFETTHIKRGSKIDNLVQIGHNVTLGAHNIIVAQTGIAGSTKTGRHVVMGGQVAVAGHLKIADEVMLAGRTGVTKSLPTSGKYGGLPAQPIEIHNRNSVFLNHIEKYIKAIKALQEEIKILKDKSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX05</accession>
    <name>A0A0C1JX05_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpsN</name>
        <name evidence="5" type="ORF">DB41_IB00990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385795.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74966">
        <property type="protein sequence ID" value="KIC74966"/>
        <property type="gene ID" value="DB41_IB00990"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1533"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="101" mass="11801" checksum="0F430C45FED83B58" modified="2015-04-01" version="1">MAKRSSIEKAKRREKVVKLKWEKRQALKKTAADINISEEERHEARVALNKMPRDSSPTRLRNRCLLTGRARGFIRQFKLSRLTFREMALHGLIPGVTKSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX59</accession>
    <name>A0A0C1JX59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">LL-diaminopimelate aminotransferase</fullName>
            <shortName evidence="6">DAP-AT</shortName>
            <shortName evidence="6">DAP-aminotransferase</shortName>
            <shortName evidence="6">LL-DAP-aminotransferase</shortName>
            <ecNumber evidence="4 6">2.6.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ald1</name>
        <name evidence="6" type="synonym">dapL</name>
        <name evidence="8" type="ORF">DB41_HY00320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23988"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="EC" id="2.6.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (aminotransferase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.83" evidence="4 6"/>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385560.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75006">
        <property type="protein sequence ID" value="KIC75006"/>
        <property type="gene ID" value="DB41_HY00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1426"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010285">
        <property type="term" value="F:L,L-diaminopimelate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033362">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01642">
        <property type="entry name" value="DapL_aminotrans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019942">
        <property type="entry name" value="DapL/ALD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43144">
        <property type="entry name" value="PTHR43144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03542">
        <property type="entry name" value="DAPAT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="7">
        <location>
            <begin position="35"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="105"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="234"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="394" mass="43728" checksum="2038FDC4A979DCB9" modified="2015-04-01" version="1">MIKRNANFAKLNNGYLFPEIHKRKLKFISDHPQAEVISLGIGDTTEPIPSSIAHAMSQEAMKLGTIQGYSGYGPEQGLNELRERIASQLYFNRISSSEVFVSDGAKCDIGRLQMLLGKHVSVAIQDPAYPVYVDGSIIQGVSNIVYMPCTPENNFFPDLERTPRTDIIYFCSPNNPTGAVATKDQLTRLVDFAKSNQTIILFDSAYASFIQDPSLPKSIFEIPGAKEVAIEVSSFSKLAGFTGVRLGWTIIPQALKYEDGTPVNADWQRLTTTIFNGASNIAQQGGMAVLEDRGLQEVKKTCQLYLENAQLIKVALEQQGWEVYGGTNAPYLWVRFKNRKSWEVFQALLENYHIITTPGSGFGPSGEGFIRFTAFGTRNNIMLAINRLKKPFVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXC9</accession>
    <name>A0A0C1JXC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Replication-associated recombination protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rarA</name>
        <name evidence="6" type="ORF">DB41_HH00180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385218.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75725">
        <property type="protein sequence ID" value="KIC75725"/>
        <property type="gene ID" value="DB41_HH00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1215"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="44"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="427" mass="48265" checksum="B2BB0DB5565C9EB0" modified="2015-04-01" version="1">MITPKSPIAPLAEQMRPASIEEIVGQEHLIGPEGFITKIISTGMPLSIILWGPPGCGKTSIARLYAKAFNIPFYSMSAIFNGITDLKKLIEEIENTPLLRQRAVLFVDEIHRFNKAQQDAFLPYVEKGTIVLIGATAENPSFHLNTALLSRLRVLSLQPLNEKSLHHLLQRYEARKKVLPLTDEARQLLILSAQGDGRFLLNLIENLQGVNENIVLDADTLQTYLQQRTARYDRQGDQHYQLISALHKAVRGSDPDAALYWLARMLEGKEDPLFLARRIIRMASEDIGLADPQALPLCIAARNTYEMLGSPEGELALAQAVVYLALAPKSNALYKAYEEAKQLAAQTTHMAPSPIILNASTPLMKQMGYGKDYMYDHELEHAFSGQNYFPKELPPRKFYHPVERGFEREMKKRQSYFDKLRIIKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXG1</accession>
    <name>A0A0C1JXG1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine protease</fullName>
            <ecNumber evidence="5">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_AE00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244091.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71932">
        <property type="protein sequence ID" value="KIC71932"/>
        <property type="gene ID" value="DB41_AE00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC71932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="480" mass="54697" checksum="1B186BD842C8D86D" modified="2015-04-01" version="1">MAIGQSVNSQLYSQDFCIENLYKLNELNLGESLEKTIQEQADSVACMMPDHKLIRINNYGFITYKFDTERVRTLGERISKKAKGIPLGHTDSFLHEPTPGLSTAFLVSPQHVLTVAHCITRSNPYTKLKPKKARGVIVRTSLKAQSELERIKFVFGFQMKSQKMRTEDYEFCESDIYSFKRVVFFNYTCAPDHLIDWALIKLDRKVIGRRPLAVNFIKKSLLNKKIFMLGHPRGLPLKIHLGASVKKECSEQHIETNLDSFHGNSGSPVIDENLEVVSILFAGNVSNKPWTTPSGYEASTKMNLPAKQLRPNPTNRTHLCQTTHGMSFVRIHLKKLKLKKQNKNLETAELSEIGAHYLNFYLSICISDQEDEAWICSVKAKAFKYLSQAAIEDHQEALCNLGICYERALGTRRDLRKAFECFKKSFENGYKNAAYHLFQCYESGIGTEKDSKLAQYYFDLAHAFGHKDVIKIEGPNCLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXK1</accession>
    <name>A0A0C1JXK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein YciF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yciF</name>
        <name evidence="3" type="ORF">DB41_HW00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385488.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75106">
        <property type="protein sequence ID" value="KIC75106"/>
        <property type="gene ID" value="DB41_HW00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1373"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010287">
        <property type="entry name" value="DUF892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05974">
        <property type="entry name" value="DUF892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF892" evidence="2">
        <location>
            <begin position="5"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="169" mass="18612" checksum="24D8114361892983" modified="2015-04-01" version="1">MKLTSMEDLLVYELQDLLSGEMQMVEALPLMQKAASHPELKAAFEKHLQETKQQVKRLEIALSYLDAEVSHTTVCKAMKGMIAEGEEIIKIHAPDDLKDAGLIGAAQKIEHYEIAGYGTAKAHAAWLSLDEVVNLLDETLQEEASTDKKLTKLAEGSMFTSGINKQASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXL9</accession>
    <name>A0A0C1JXL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HC00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000113">
        <property type="protein sequence ID" value="KIC75830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75830">
        <property type="protein sequence ID" value="KIC75830"/>
        <property type="gene ID" value="DB41_HC00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5310" checksum="2EE39C3CC69672F7" modified="2015-04-01" version="1" fragment="single">MKFDKIEKLNDERFRRLTGIKRSTFDKMVQILQQADAAKKIKGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXQ9</accession>
    <name>A0A0C1JXQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384970.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75860">
        <property type="protein sequence ID" value="KIC75860"/>
        <property type="gene ID" value="DB41_GZ00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="103" mass="11981" checksum="3E3278C680BDA495" modified="2015-04-01" version="1">MITDIESLNLLDLDQFSADLEELKQEIITEEAEGDEDDVILEVIKVIQEEIVKRKSNPEKKDLASNVKFLAYINLFNSLFGEVDFEELDEDELEDIEEDEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXT4</accession>
    <name>A0A0C1JXT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ParA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">parA</name>
        <name evidence="3" type="ORF">DB41_AA00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386553.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72022">
        <property type="protein sequence ID" value="KIC72022"/>
        <property type="gene ID" value="DB41_AA00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2075"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="2">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="250" mass="27680" checksum="60019907F5A871FC" modified="2015-04-01" version="1">MHCIAISSFKGGTAKTSSALHLGAALAKFHKKKVLLIDFDAQANLTTGLGFDPDENDSMATVLQGNKTLKEVIKKTSVGNLDLIPADTWLERVEVTGQLASDRYSHERLSDCIKDAPYDFTIIDTPPSLCWLTESALIAAQHALVCATPEFYSVKGLERLSQFMESIGQRHPLNLLGVILSFWNPRGKSNEAFLEVIDKTFPKKLLKTKIRRDICVSEASIFGKPIFDTVPNSRAAEDYIALTKELLKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ42</accession>
    <name>A0A0C1JZ42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384748.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76280">
        <property type="protein sequence ID" value="KIC76280"/>
        <property type="gene ID" value="DB41_GL00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="258" mass="30520" checksum="BB6291FB83F2A538" modified="2015-04-01" version="1">MFFALEVKAPWPEKLPKGRVLDPHTRHATLAFVGEISLSALFQHAFPHPSFRVGLVGAFNECLFLPFHHPNVVAWKFDWYDESKELIEYRQKLSNWLSMHHYPLRDNHKDWLWHVTLSRKPFDHKEWQAAFTPLPMLTQSLHLYASLGHLNYQPLWSYSFIPPFQEIKYPNQTVYLINGENLNQIYQHAFAALAFHYPPLTSYHHTKNYAHLKEIIADLNFLIVRVKADQDCPLKTLHVYKDIQTKDSIIQFEMIMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ46</accession>
    <name>A0A0C1JZ46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative rhamnosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rgpB</name>
        <name evidence="2" type="ORF">DB41_KK00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244056.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72492">
        <property type="protein sequence ID" value="KIC72492"/>
        <property type="gene ID" value="DB41_KK00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1954"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="315" mass="36896" checksum="12B5A02376CC3B09" modified="2015-04-01" version="1">MESKLSFSNPRKVDILLATYNGERYLAEQIESLLKQTHPDIHLLIRDDASIDNTPLIIESFLSKFPDRITFFQGRERQGVKANFSQLMQASTSSYLMFSDQDDVWKPNKVEKSLSCMIAMENKYGELPLLVHSDLTVVDESLNLLDPSFWHYTYLNPPHSSSLNRLLTQNVVTGCTIMINRLMNELARPIPHEAFMHDWWLALIASAFGQIGVINEATLYYRQHSTNTLGAQKFFNFCNIKKKLHKWRQTDEKKFQQAFIFFHRYQELLSLSQQKILKDFLMLAHLPWMKRKKTIYCHGFFKQGWVRNLADFFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ58</accession>
    <name>A0A0C1JZ58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="10">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="10">DXP synthase</shortName>
            <shortName evidence="10">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">dxs</name>
        <name evidence="12" type="ORF">DB41_HH00040</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385195.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75711">
        <property type="protein sequence ID" value="KIC75711"/>
        <property type="gene ID" value="DB41_HH00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1201"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="11">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="148"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC75711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="633" mass="70300" checksum="56E29B41DC950221" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ67</accession>
    <name>A0A0C1JZ67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HH00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75726">
        <property type="protein sequence ID" value="KIC75726"/>
        <property type="gene ID" value="DB41_HH00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6622" checksum="1BF840F346FA7B4D" modified="2015-04-01" version="1">MSSLSCKLIRHENHAFGQKANFARLNFLGSTDLASLKSMAYENKGLSLTFLFMVKAIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ71</accession>
    <name>A0A0C1JZ71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase H</fullName>
            <ecNumber evidence="1">2.1.1.177</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (pseudouridine1915-N3)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m3Psi1915 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (pseudouridine-N3-)-methyltransferase RlmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">rlmH</name>
        <name evidence="2" type="ORF">DB41_HH00290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10221"/>
            <dbReference type="Rhea" id="RHEA-COMP:10222"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:74486"/>
            <dbReference type="EC" id="2.1.1.177"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA methyltransferase RlmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.177" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385233.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75736">
        <property type="protein sequence ID" value="KIC75736"/>
        <property type="gene ID" value="DB41_HH00290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1227"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070038">
        <property type="term" value="F:rRNA (pseudouridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18081">
        <property type="entry name" value="RlmH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00658">
        <property type="entry name" value="23SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003742">
        <property type="entry name" value="RlmH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33603">
        <property type="entry name" value="PTHR33603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02590">
        <property type="entry name" value="SPOUT_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004505">
        <property type="entry name" value="MT_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="108"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="15821" checksum="7589FEE77C612A3A" modified="2015-04-01" version="1">MLRLKIISIGKTKEEWLNDAIQKYVKRLSPVLNFEFVEAKNNAQLQELISKEKRVICLDAAGQLLDSEKFSSFLQVQFIEGGSRLTLVIGGASGLPENIKLSYPCLSLSPLTMTHQIIRLVLIEQVYRAFEIAKGTPYHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ85</accession>
    <name>A0A0C1JZ85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KJ00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72532">
        <property type="protein sequence ID" value="KIC72532"/>
        <property type="gene ID" value="DB41_KJ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="5198" checksum="F028890DF5BEC48B" modified="2015-04-01" version="1">MKVNKKYFKPTELTFFQKENILTIRFASFSCNKEASEQEMENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZA6</accession>
    <name>A0A0C1JZA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HF00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75781">
        <property type="protein sequence ID" value="KIC75781"/>
        <property type="gene ID" value="DB41_HF00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4995" checksum="AABDA4C706B3BEE1" modified="2015-04-01" version="1">MLFFNYLNFFNLKRFNLTQLAPAFQEKAKLSSSYKTLQHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZP8</accession>
    <name>A0A0C1JZP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KD00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72717">
        <property type="protein sequence ID" value="KIC72717"/>
        <property type="gene ID" value="DB41_KD00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1875"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="37"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="28748" checksum="9FF0A9274A802E15" modified="2015-04-01" version="1">MKEVSKTHFRPSLNVLLLSQSTILEQLQLEEALLRADQRNWCLINPNPPEAIVMGISSSPEKVIDLDRLQKQPVPLIRRFSGGGTVFIDADSIIKTFIFNQADLGIPCYPHAVFQWSEIFYRLVFQEIELRLCENDYVIKGRKCGGNAQYMTKNRWLHHTSFLWDYQAENMAYLKMPPKMPGYREQRSHDNFLCKLGEYLPSKQEAVNRFLKTLEVYFKVEISSLSEAYKVTQIPHRRTSQRIDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZT7</accession>
    <name>A0A0C1JZT7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_GU00150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243912.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75966">
        <property type="protein sequence ID" value="KIC75966"/>
        <property type="gene ID" value="DB41_GU00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1035"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="189"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="361" mass="40750" checksum="CC0464A7358C40F3" modified="2015-04-01" version="1">MTLPRLLIISAIILFSIIGVAALFKNKSPHANFIIEPATSHPPIEIEIKSNSFSNSALPSLSQTPSSPLPIPSLKAKDKELSDKDSDDQLNSSEKVLELKAQLPEENRVVEFFNTTSPKFPIVETITYKSRVNWQKGRPAWLSDYANYYKTSRHFIARSLNGKPDYLKQDISEGARFNILHPHKMIHFHLLIDLSRCQMWFYYYDINAKEKVLVKTYQVGLGRLDPSTNSGLLTPLGIYSLGPRVAVYTPKIMGIHQGAKVEMIRIFGTRWIPFEKELHGTTAPAKGLGIHGMPWLIKNGTLVEDTNSLGKYESDGCIRMAAEDIEELYSIIISRPTTIELTKDFFKAENNMQTIIEIANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZV7</accession>
    <name>A0A0C1JZV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KC00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72817">
        <property type="protein sequence ID" value="KIC72817"/>
        <property type="gene ID" value="DB41_KC00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1857"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5307" checksum="DB69564BA5474033" modified="2015-04-01" version="1">MLIFFRAKQGALIIFFGIYSIKKRLIYGSRENGLKKLAKHKHCLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0R1</accession>
    <name>A0A0C1K0R1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">queD</name>
        <name evidence="11" type="ORF">DB41_EO00080</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76755">
        <property type="protein sequence ID" value="KIC76755"/>
        <property type="gene ID" value="DB41_EO00080"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="8083" checksum="7FCEC36B653362A4" modified="2015-04-01" version="1">MYELEKIFCFEAAHFLNHHDGKCKSMHGHSYSLHVIIRKESLQKEGPKKNMVIDFQDLADLVQPMLKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0R2</accession>
    <name>A0A0C1K0R2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GI00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000094">
        <property type="protein sequence ID" value="KIC76336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76336">
        <property type="protein sequence ID" value="KIC76336"/>
        <property type="gene ID" value="DB41_GI00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="111" mass="13047" checksum="504962653F681EDB" modified="2015-04-01" version="1" fragment="single">MPRKRNMIELQQVIFRLKLKQSIRSINRDTGIHRTIIRNLNKVANNSGWLSNDRSIPSENEIHQALVAFDLKKSSKPHDLDFFKPLIKDWLAKNHSFVVIHKLIQEYITCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K101</accession>
    <name>A0A0C1K101_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EH00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383786.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76825">
        <property type="protein sequence ID" value="KIC76825"/>
        <property type="gene ID" value="DB41_EH00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="427" mass="47574" checksum="A3F15C5645F73349" modified="2015-04-01" version="1">MNTLSSTQGVPPTEPYYGEEEDFIQGQLDGHTVTVEQAPASQHKPANNLASSSRNKITNCAKKVSENFSHAVRHIVAFYAYSFSTSESIQSVCKLAKSSIYFAKYAFKAQTPGFNNLYNHFDVVDTVLDVGGIFGDAKYWVTKGWHKDSSWKVASKAFGSVSRGIGTGQFLVNMGLLNLAKVSVQLNRLPFFRVLSLLSPLRVIKDTLGIISSSLSLVDTSLALQKKNSDVTSEIEKLRLNKWELKKRAIKFLNLNETQKAAKLKAKFGKEKFEKTSADALEQEYLNDLDKKFLSLREKLVSQYEQRLHSTHATLFDSIADKKLVDCKVRIVERDQLVKDYQASKTKDWLSIAFNVVKIAAIAMGLVGFALTLNTAAFFIALGAAWLATSAVGMARLYYSFRHETYKEEQEAKLTRLTTLGPVAFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1D4</accession>
    <name>A0A0C1K1D4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DS00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243789.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76920">
        <property type="protein sequence ID" value="KIC76920"/>
        <property type="gene ID" value="DB41_DS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="461" mass="53132" checksum="E1FD9B2312B25FFB" modified="2015-04-01" version="1">MHSLSFVPHIRIPEEVLLKILSLLDEKELPIVALVNKHWQRMAQDPSLWRPICQRRWKNLSRSSSPGKNWRKICKKRVQMSQTMRLTKGEYSKNKCKQTIYKLPNFSGKILALKREKQFAFIKATAGTAQIYHLGEKSCQLVYDNVKEESSRLIHYQEGHIIQVTQEGQLYRWKVNEAFPTTSLCYLENFEEAYFAQNHLFLVNSHHTQFKIVDVRTGLSCYKTTLAPINFILCRNNQALIHCLDGSLYFINNLESSFSSSLMALEGNLKSPLNQELCQFDEARVIVLCEDDLQRRCHIWDASNGKKKIEFTLAPRPVEKCWDKKSILTTSSYDGKRLAVGLSIGFVLIYDVDDGNFLTSSNIGDIDSVRFLALDENHFLASTFHPEFKSFELYQHTPAKKCGGIILPFLPNTYPWVNSNTIHASYDGHKLVFCDEHGWLHLWDFAHLQGKEPILVAPPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1I2</accession>
    <name>A0A0C1K1I2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76955">
        <property type="protein sequence ID" value="KIC76955"/>
        <property type="gene ID" value="DB41_DP00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4995" checksum="0CC5CBDE8971A697" modified="2015-04-01" version="1">MQAIKKATISSLRDSILFILYLNLSTDELEKPFKFIPIKKLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1K2</accession>
    <name>A0A0C1K1K2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76965">
        <property type="protein sequence ID" value="KIC76965"/>
        <property type="gene ID" value="DB41_DP00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="6433" checksum="CBF4F21091CF08C4" modified="2015-04-01" version="1">MGYADLALLKGMLTNLLKRLRRFLFFLKLLASFTSVKAQEVKNLNLTISFHDFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1R7</accession>
    <name>A0A0C1K1R7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FH00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384120.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76626">
        <property type="protein sequence ID" value="KIC76626"/>
        <property type="gene ID" value="DB41_FH00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="114" mass="13141" checksum="4A50ADAE492CB893" modified="2015-04-01" version="1">MGQIYKEQGNLEQALKHVKRALDIGLKLFGENHSSVIKNYYNLGQIYHDQGVLNKAILYTKKSIATSLRYHGADDLYVLKGYCTLMTIYRRQGKLEQATKCFLISRKIIQSRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K236</accession>
    <name>A0A0C1K236_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_ET00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76731">
        <property type="protein sequence ID" value="KIC76731"/>
        <property type="gene ID" value="DB41_ET00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7213" checksum="C863BC0F98D0A09B" modified="2015-04-01" version="1" fragment="single">MLYNNVEDEAHLFKTDSWRLFRIISEFVEGFENMTTLGPSVSIFGSARLQASHPYYKLGIDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2C3</accession>
    <name>A0A0C1K2C3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transposase for insertion sequence element IS702</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CX00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383307.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77150">
        <property type="protein sequence ID" value="KIC77150"/>
        <property type="gene ID" value="DB41_CX00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.170"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027805">
        <property type="entry name" value="Transposase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13613">
        <property type="entry name" value="HTH_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_4" evidence="2">
        <location>
            <begin position="47"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="152" mass="17895" checksum="45CC7DDED91914BF" modified="2015-04-01" version="1">MKFEIVKDLDDERFRRLAGVKRTTFNKMVGILDQSIKNRRVNSGRKKKLGLENMLLMTLEYIREYRTYFHVGQSYGVSESTAYKTIKWIEDTLIKHPDFALPGRKALLKRDVEYDVILIDATETPIERPKKGKNTFTRKKEKAYPKESSDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3B3</accession>
    <name>A0A0C1K3B3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77261">
        <property type="protein sequence ID" value="KIC77261"/>
        <property type="gene ID" value="DB41_CO00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="5107" checksum="546E00445BECA320" modified="2015-04-01" version="1">MAFIIEIFLFYPAAFYFLKTLLLHNFPSQFECFRLFIKLKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6T0</accession>
    <name>A0A0C1K6T0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74942">
        <property type="protein sequence ID" value="KIC74942"/>
        <property type="gene ID" value="DB41_IB00750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4803" checksum="E15C22262EFA903A" modified="2015-04-01" version="1">MNMASLLLMRIGLIKKFSYFLQFSIQRQQLKFFSEESAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6Y5</accession>
    <name>A0A0C1K6Y5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HY00180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385554.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74992">
        <property type="protein sequence ID" value="KIC74992"/>
        <property type="gene ID" value="DB41_HY00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1413"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="380"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="666" mass="76053" checksum="C75C929762D70CE3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7F2</accession>
    <name>A0A0C1K7F2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385472.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75092">
        <property type="protein sequence ID" value="KIC75092"/>
        <property type="gene ID" value="DB41_HW00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="386" mass="42210" checksum="83BBCBB9B6539114" modified="2015-04-01" version="1">MPLDKLNSSLERTWELNTSAETHDSSYLKKQGSAPAEVQPSLYASSITSLKPIEVATQAVQNEQLHGKKNKSAFAWMENLRNTLMSYLGAQQKKASVPALEAQQKMKILLESTTQVCALEELKNKSSAIHKQPETIKIEALGKQKKGFLYQLGDWIKGKWSFFSGSSKGSKPAEKIIEREYSSQAKPLAHRSPKEIDEDFKYLDITAMDPLKAMLAILVKQGELRQEQATLINQQILHRQQDLKALHAERMQIQAELALIGKRAGVLEKVSVGLTVTQALGGIASAAMVVAAAATIATGGAAAPLLIVTGVFNGMAGAGQTFNTWLKGDTKNKLNKLQGEMLAKSSQRDEYQFQLKVDVQEIKKALGSLISHAEMGSGLLYAQYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9F2</accession>
    <name>A0A0C1K9F2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75807">
        <property type="protein sequence ID" value="KIC75807"/>
        <property type="gene ID" value="DB41_HE00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4711" checksum="17AAE0A307CE722C" modified="2015-04-01" version="1" fragment="single">PLVHQIDLVTSRCPCCHLETRSELKENEQFLLGLKARRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9I6</accession>
    <name>A0A0C1K9I6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent RNA helicase RhlE</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rhlE</name>
        <name evidence="11" type="ORF">DB41_GZ00060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75842">
        <property type="protein sequence ID" value="KIC75842"/>
        <property type="gene ID" value="DB41_GZ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1071"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="235"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="374"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="405" mass="45191" checksum="78B0362F9DCF30D6" modified="2015-04-01" version="1">MTFSELNLHAGILKTLENEGLTTPTPIQLEAIPKVLAGYDLRASAQTGTGKTAAFLLPALNRLTTPSAVPGQGPRILILVPTRELAMQVAEEARRFSANLSRVKTVCIYGGAPYPLQNRELSRPFEILVATPGRLIDHMSRGRINFNRIEMLVLDEADRMLDMGFIEPVEKISAAIPKQRQTLLFSATLKGNVLNLSNRLMNNPIEISVISENSRHENIEQRLHFVDDMHHKSRLLDHLLNDPSVNQAIIFTATKRFADQLVDILYENGHPAAALHGDMNQRQRSKTIMRLRDGEIRVLVATDVAARGIDVQTISHVINFDLPTNAEDYVHRIGRTGRAGAKGIALSFAASKDMRLVRQIEQFTGYTITPSVIAGMEPKSKPSKPSSSFKQKRPFKPHFKRAQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBG8</accession>
    <name>A0A0C1KBG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_FX00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76492">
        <property type="protein sequence ID" value="KIC76492"/>
        <property type="gene ID" value="DB41_FX00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="120"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="246"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="290" mass="32762" checksum="3DC8A1F13419DB5A" modified="2015-04-01" version="1">MVIYKEQGNMQKAFEYAHQALAIDVKQFGENHSNTARDYHHFGQIYKAQGNLGKATEYAEKALAINHMLFGENYPEIASDYNDLGQIYKAQGKLEQAAEYTEKALAIDLKLFGENHSEVAILYNNLGMIYKEQGNLEKAAEYVNLALVIDHKLFGEEHPMVASRYANLGLIYQEQRDLEKAAKYTNKGLDINLKLFGENHPIVAIGYSNLGQIYKEQGDFKQAAKLTKKFIKISLKLHGADSRDVFKGFNDLGIIYHRQGKLEEAAKCIKQALKIGIKLWGENNLTVVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBM6</accession>
    <name>A0A0C1KBM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS4 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FR00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000079">
        <property type="protein sequence ID" value="KIC76537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76537">
        <property type="protein sequence ID" value="KIC76537"/>
        <property type="gene ID" value="DB41_FR00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.752"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039365">
        <property type="entry name" value="IS701-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33627">
        <property type="entry name" value="PTHR33627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_5" evidence="1">
        <location>
            <begin position="21"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="390" mass="45300" checksum="675D50A6FBE249EA" modified="2015-04-01" version="1">MELKAINQTIKQKKEELALFLRPFFSREEARQVALQYTWGLMSKAERKNTWQLAEEVGLQTPYAFQHLLRRGLWQADAIRDRLQMEVLKDKEGGILAIDETGFLKKGKHSAGVARQYSGTAGRIENCQVGVFLSYATSQGHVLIDRELYISEEWFLDEERRARAGIPKEVKFKTKIQLAMLMLQRAFGHGIRPSWVLGDEVYGVYPLRAYLEKECCPYILAVPSNYHVSVDFDRSPVSHFLAEIKPKDWQSLSAGKGAKGERYYHWYRLEVNSDSPEGWTRWLLLRRNMKEPRDVAYYIACCPNNVTLQDMAKAAGSRWTIEECFEASKGEIGLDHYEVRSYTGWYRHMTLCLLALTFLSGLRDAFNLLEKKKKARRLHMKKFLKVRNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBP3</accession>
    <name>A0A0C1KBP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FO00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000076">
        <property type="protein sequence ID" value="KIC76552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76552">
        <property type="protein sequence ID" value="KIC76552"/>
        <property type="gene ID" value="DB41_FO00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.739"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="10197" checksum="73CD9D4E2E176808" modified="2015-04-01" version="1">MGKFRRSTHQYHKSIKQNASLEKSPTKIARSQRNHIFSSLIAYCKLEFLKIKTLLNHFALKYKLILKANQMAYQELQNLQRNFMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBR0</accession>
    <name>A0A0C1KBR0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FN00140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384296.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000075.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76567">
        <property type="protein sequence ID" value="KIC76567"/>
        <property type="gene ID" value="DB41_FN00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="8719" checksum="060AC83D588E14BA" modified="2015-04-01" version="1" fragment="single">ELKAGQVLIMDNATFHKSQATHELIKKAGCEILFLPPYSPDLNPIETFWANFKKIVAANVSKFSTLAQTIDYSFLSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCE6</accession>
    <name>A0A0C1KCE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TPR repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_EN00020</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000053">
        <property type="protein sequence ID" value="KIC76767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76767">
        <property type="protein sequence ID" value="KIC76767"/>
        <property type="gene ID" value="DB41_EN00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.533"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="177"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="261"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="303"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="352" mass="38789" checksum="959A7B430330B28E" modified="2015-04-01" version="1" fragment="single">FGENHPTVAIDYSNLGAIYHEQGNLNKAAEYINKALAINLNLFGEYHPDGANCCNNLGTIYREQGNLNKAAEYSNKAFAIDLKLFGEYYPKVAIDYNNLGLIYQDQGNLSQAEECSSKALAINLKLFGEYHSSVATNYNRLGQIYEDQGNLDKAEEYTKKALAIELKLFGENHLEVAICYNNLGAIYLEQGNLSQAEECSSKALAINLKLFGENHPDVAIGYNNLGLIYKDQGKLGQAEECSSKALAINLKLFGENHPDVAIDYNNLGTLYQEHGNLGQAAEYVKKALAINLKLFGENHPDVAIDYNNLGQIYKEQGNLSQAEECSNKALAINLKLFGVYHSSVATNYNSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCJ9</accession>
    <name>A0A0C1KCJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76807">
        <property type="protein sequence ID" value="KIC76807"/>
        <property type="gene ID" value="DB41_EI00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="39"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="405" mass="46383" checksum="B35AF492B2856D5A" modified="2015-04-01" version="1">MDKIMHQLSSGTFHIHPLIFPAFENQEKQSKDSIRNTTVYAEIALKIFKELGLQDLCRTQLVCKEWKQLIESSFLAKEKAYTLALKHAIRKKDLIQEAFYIEKLGDVYVQKGTSEAFLQAAGLYNYALHRHFLSHPLEGKQKVLKEKLSKIQDLLVRECKGRSVGSATIEDQFESNRKTLKEFRTEIEAKIQELPETPSSQEVMELYHKIAQGIKTFFEHIVAQSLDTLGSPPCKYSMIGFGSLAREEMTPYSDLEFGILIQEDNPINRDYFRRLTTLLHLKVINLGETILPALNIPCLKAINFFDDITPRGFAFDGAGVEGKGCKTPLGNGKTFELIQTPEKMAQYISKDNENQWWHEREPHLPMELLNFAHLQGSRELTEQYNENVQKNLMLLAKKALLCVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCU5</accession>
    <name>A0A0C1KCU5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 8" type="primary">grpE</name>
        <name evidence="8" type="ORF">DB41_DW00040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76892">
        <property type="protein sequence ID" value="KIC76892"/>
        <property type="gene ID" value="DB41_DW00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.409"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="35"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="23815" checksum="079B37D503154CA7" modified="2015-04-01" version="1">MTIEDIPDKDESTQSLEKQAALEKESKHKREPKTVHISDLELEHLKREIHEYKDKYLRSIAEAENLRKRLNKERQEMMQVAIQSVIVDFLTPLDHMEKALSFTDQMSEEVNNWATGFKMILNQFKEALTNNDVHAFKSVGMPFDPHHHEAVEMIETTEFPEGTVVEENTKGYKMGGKIIRPARVKVAKKTNSEPHIEENLSSSTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDK4</accession>
    <name>A0A0C1KDK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DE00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000021">
        <property type="protein sequence ID" value="KIC77082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243762.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77082">
        <property type="protein sequence ID" value="KIC77082"/>
        <property type="gene ID" value="DB41_DE00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.225"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="400" mass="45693" checksum="EC49E50AB376E2D8" modified="2015-04-01" version="1">MHPISSTSIESLPNELLLPILEVCIVPSLFGVCKRWHHLLASEVMPSLYKQIGKVHVSQGDISKQALIVDRIYKLEEKLTEAAKVNAIFKQIFTLAKSLSLLKFKWKTEEKKYFTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEKKGELLRDWMEENCKNITSLDLSRAGLTYLPPEIGQLSQLQLLYLNQNQLTSLPAEIGQLSKLRELYLNQNQLTSLPAEIGQLSKLRELYLDQNQLTSLPAEIGQLSQLEWLYLNQNQFTSLPAGICQLSQLQELCLDQNQLTSLPGEIGRLSELQTLDLNQNQLTTLPAEIGQLSQLQWLYLNQNQLTALPAEIGQLSELQTLELNQNQLTALPTEIGQLFQLEELELAENPLKNISEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDQ0</accession>
    <name>A0A0C1KDQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DB00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383346.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77097">
        <property type="protein sequence ID" value="KIC77097"/>
        <property type="gene ID" value="DB41_DB00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="195" mass="22402" checksum="1CD0BC4E0CA86BCD" modified="2015-04-01" version="1">MNKIYIGIACLFLLSIGELHAFVDEQPMTLEIRSAAFIHANKRFKKLYGKIGTSYQIEASLPLPPFEYLRGWSNFDYFSKHSRAHRDRCCGKSKVEIPQISFGIKYIYPFREFLDGYVGIGPSFSRINVTNKSCCLHEKVSKFAVGGILKSGIYYSMSKRIFMDVFIDYLYQPVHFKKYRNVGGFKAGAGFGYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDS2</accession>
    <name>A0A0C1KDS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CZ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77122">
        <property type="protein sequence ID" value="KIC77122"/>
        <property type="gene ID" value="DB41_CZ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5874" checksum="C590DA006037EDE8" modified="2015-04-01" version="1">MLAVWRKNGRIFKVSSYLPFFLSYLLELLFSLTASVEGAQLKKFINRLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDU4</accession>
    <name>A0A0C1KDU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CX00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77147">
        <property type="protein sequence ID" value="KIC77147"/>
        <property type="gene ID" value="DB41_CX00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.167"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="80" mass="9027" checksum="8014BEDA2BE03E77" modified="2015-04-01" version="1">MILTEDQLKALEKAKEEKEAHGEIETANPGYLLSQDTYYVGTIKGVGRIYQQTVIDTYSKVAFVKLYDRKNALVAADMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE20</accession>
    <name>A0A0C1KE20_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PTS EIIA type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CP00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383165.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77222">
        <property type="protein sequence ID" value="KIC77222"/>
        <property type="gene ID" value="DB41_CP00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.82"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004715">
        <property type="entry name" value="PTS_IIA_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00848">
        <property type="entry name" value="fruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="149" mass="16862" checksum="F13F8243CF86B633" modified="2015-04-01" version="1">MIKISKYLDSRNILFMSAEDRDEALHTMVENLHQNRFLHDKEAFYQAILEREKVVSTGIGMGVAIPHAKLKGYESFFIAIGILQKGVDWNSLDGSPVRIIIMIGGPDDKQTEYLQILSALTTAVKDENRRKKMLTLNSAEAIMTLFKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE26</accession>
    <name>A0A0C1KE26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CP00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383171.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77227">
        <property type="protein sequence ID" value="KIC77227"/>
        <property type="gene ID" value="DB41_CP00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="184" mass="20848" checksum="8713C0372EBB740B" modified="2015-04-01" version="1">MIPSISTSNTHPNFRLAVSENIEDAVSGKLMTRAVTLFPCGHTFNEETVISCLARNKLCPLDSQLIERHTPNPTIRLQAQIAEADFLSEFFRERYIALLGHLLNAPSIKAIPSLASLLENQFKTLMSQFGEQLTNEERLNYNWTKNLLDKNEKVRLFAFKRLQQSYQRSTSPSMVSPPSVFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1R9</accession>
    <name>A0A0C1H1R9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AU00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386857.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000217.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71624">
        <property type="protein sequence ID" value="KIC71624"/>
        <property type="gene ID" value="DB41_AU00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="223" mass="25449" checksum="A261F47808CED5A5" modified="2015-04-01" version="1">MTDPNIVERDATSIKALHYFFSKNCKVEKECEGAHISIIPRFTVISSENRMQYEYKDNKLYQRLNTVDYVKAVINRIDDEIEKDGRLFAIQLLNKIIKGKENISSAVVEFRRYIGKVLERINQGIFRTSNYKGRQQEEARGIAGSLFGQYTTSITTTATSSTPSDATSTSSPSLSEAELPPTPQIRDVRGEEALPEKEKKQAKRKKRRNKYKETLMAFKITPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1Z5</accession>
    <name>A0A0C1H1Z5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AQ00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386778.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000213.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71714">
        <property type="protein sequence ID" value="KIC71714"/>
        <property type="gene ID" value="DB41_AQ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2191"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="133" mass="15051" checksum="07E6E9D90B38FCBB" modified="2015-04-01" version="1">MPIRIALNLFTLFPLVLISFCLRAEPWGKDADLAHLKPASLQDQPYCCTTPLMGPVAESLIGFHQTIITPIDGPRSNYLPSSSQYTLDAMRKYGFFVGFSMGCDRLMRENDDPWIYSKVTDQQGYLLKYNPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H230</accession>
    <name>A0A0C1H230_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2063 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AM00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244110.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000210.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71744">
        <property type="protein sequence ID" value="KIC71744"/>
        <property type="gene ID" value="DB41_AM00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2178"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018640">
        <property type="entry name" value="DUF2063"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09836">
        <property type="entry name" value="DUF2063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2063" evidence="1">
        <location>
            <begin position="19"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="299" mass="35830" checksum="DBB0AFE6FB161578" modified="2015-04-01" version="1">MKAMELAFDKQVPANLRKLQEWFASILVRPVDQDSRMNPISPSQESMEEEAFDYIVPSPTLRPAQRIELYNQQYWWRLLSILHDATPLVVRLFGHHDFNEKIGKPYLTHYPPDTWSLNFLSDRLPQWIDESYQEKDKQLVLDAARIDAALNYSFFAAHYSPVNAPTIAVGMDKTLKRRMRLQPHVSLFNLRYDMFTFRQEMIKQEVEYWENHDFPSLVQDRPYYFVVYRNGENNLQWDEIDFSAFRFLNLFSTGTSLEEACEWLEQQDEQLYAEAASKLHLWLQEWVFQQWLYFDDKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H288</accession>
    <name>A0A0C1H288_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AI00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244102.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71794">
        <property type="protein sequence ID" value="KIC71794"/>
        <property type="gene ID" value="DB41_AI00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2156"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="191" mass="21447" checksum="15842BEBEBB1EE59" modified="2015-04-01" version="1">MSQLQTLDLRENQLTSLPAEIGQLSNLRHLYLNQNQLTSLPAEIGQLSELQTLNLSQNQLTSLPAEIGQLSQLQQLHLSNNLPSIIPIEMSQLSQLQSFDLSINQLTIIPKEVGQLSKLQYLDLSKNQLTTFPTEIRQLSQLQELDLHDKQLTTLPAEIGQLLQLQVLDLKNNQLIFVPIEIGADIKGIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3K4</accession>
    <name>A0A0C1H3K4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386536.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72109">
        <property type="protein sequence ID" value="KIC72109"/>
        <property type="gene ID" value="DB41_KU00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="291" mass="33109" checksum="2FA2AF77A45C20B0" modified="2015-04-01" version="1">MSSPMRRVEEVKDFKMNKILGSLNSMPKQGVSWKGHTWNIIKDNLNSFIKSIRTRHWISGKQYRNDKLSETLKLLSATVITKLKGTMQESNLEIQLNSSDQEIDGYSLHQANYLLALAVKTHAMKINEILEKIDTPRFNAKNASYLNRIKATVRGLNNSCQIGLEAETDFINKAQEKKLKDFNREEEMKILPDKLHEELKALQEALGKYINPLSSEEEDRSSRMARDSLGLAIASIDTGIEAEELKKESKRAIKLTEGFLKEASISSEEIKTILGKLKATHERYANSLKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5T1</accession>
    <name>A0A0C1H5T1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KA00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000183">
        <property type="protein sequence ID" value="KIC72839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72839">
        <property type="protein sequence ID" value="KIC72839"/>
        <property type="gene ID" value="DB41_KA00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5211" checksum="47C7D848134A88D6" modified="2015-04-01" version="1">MQIKEAKELIFEVPYDKTAVIIQGYRAFKTISCYKGVEQRGVVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBS8</accession>
    <name>A0A0C1HBS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74879">
        <property type="protein sequence ID" value="KIC74879"/>
        <property type="gene ID" value="DB41_IB00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4610" checksum="D5B59274C916420B" modified="2015-04-01" version="1">MSTSTFLYTALAAYRPFKKLLALSINLAYYQAHKTKRTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBU3</accession>
    <name>A0A0C1HBU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KP00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72273">
        <property type="protein sequence ID" value="KIC72273"/>
        <property type="gene ID" value="DB41_KP00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="36637" checksum="1D1B8CC4CD1FCCE2" modified="2015-04-01" version="1">MILLPFSKQAPRQYNERLVVHTISLTPPKIQTKSSPLPSENKEKLALNSNILPGPKSPEEIAAKLIASPPPIPLNVEEAKPHTSSSAPTESTQKIETPSSTDKKNIKALNSTAIQQTPNKKAVPKKENAIPQSTHSKTGKPSIKKDNTKKSVSPASTAAKPAEKKPIKAPLKKTSAEAQHESPNSQASPEAKEKQKKLLAAAQASLAKLEQSRAHRNASSSQASQTALASAATIPALQTDTLPAAYTLPSSAVERSYRDELASRLKLLLKLPEHGEVQLKLTVDRLGRAIKVNIIKSPSHLNRLYIEKNLPTLKFPPLGKDFANMSEYTFIIQLSNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCI4</accession>
    <name>A0A0C1HCI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1</name>
        <name evidence="3" type="ORF">DB41_HW00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243953.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75099">
        <property type="protein sequence ID" value="KIC75099"/>
        <property type="gene ID" value="DB41_HW00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1367"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="560" mass="63272" checksum="B8185CF154DFDC33" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCJ6</accession>
    <name>A0A0C1HCJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75124">
        <property type="protein sequence ID" value="KIC75124"/>
        <property type="gene ID" value="DB41_HW00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5448" checksum="E6DA1C391AEE1726" modified="2015-04-01" version="1">MKPIKLDNQQGRLFKSRFSDELNPDHLLIQLSKLIGWKQLKEKKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCN2</accession>
    <name>A0A0C1HCN2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KI00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386335.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72558">
        <property type="protein sequence ID" value="KIC72558"/>
        <property type="gene ID" value="DB41_KI00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039588">
        <property type="entry name" value="FBXO4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16008">
        <property type="entry name" value="PTHR16008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="100" mass="11811" checksum="781AFF2454E84A50" modified="2015-04-01" version="1">MGVNFNLSFNHLPTELQVAIFSLLPEKDLGMAALVSKPWKQLAEDPFLWKKLFCRRWSNLTQIKTSRFGWKKIYKKSMFLESRAPLFLLNIFIIRCISFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDA9</accession>
    <name>A0A0C1HDA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HM00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000123">
        <property type="protein sequence ID" value="KIC75394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75394">
        <property type="protein sequence ID" value="KIC75394"/>
        <property type="gene ID" value="DB41_HM00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7367" checksum="A2BAC2CC0C76F3D8" modified="2015-04-01" version="1" fragment="single">MIASFSKILCLIMFIVILNLSLYAVEAYQVIFQGVSHPETLSLLQTISKTVELQNSPPSTNRGLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEV3</accession>
    <name>A0A0C1HEV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="1">6.3.4.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queC</name>
        <name evidence="1" type="ORF">DB41_GU00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384884.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75969">
        <property type="protein sequence ID" value="KIC75969"/>
        <property type="gene ID" value="DB41_GU00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="229" mass="25148" checksum="D4D825B2E8CA13C7" modified="2015-04-01" version="1">MRKKKAVVIHSGGMDSSICLALAMQELGKDAVTSLSFYYGQRHASEIIQAEKICKDWNVAHATLNLSCLSQVTANALINPAVAIEKDPPTTPNTLVVGRNGLMARLGAIYADYLGASFIYLGVIGVEGNYSGYRDCSREYFDLKQKILRIDLANPHFKILTPLVSLTKKETLEIAHRLGILEYLLNTTITCYEGISQAGCQQCPACRLRNKGLQEFKEANPGVLLNVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFD5</accession>
    <name>A0A0C1HFD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III subunit delta</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">holB</name>
        <name evidence="1" type="ORF">DB41_GN00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76099">
        <property type="protein sequence ID" value="KIC76099"/>
        <property type="gene ID" value="DB41_GN00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.970"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="334" mass="38300" checksum="8B7FFC634E97B451" modified="2015-04-01" version="1">MTSNMREVFDHILGNERVKDYLVNMVQKQAIGHSLLFAGPEEACKDQFAFSLAKLLMGENSYSKIDRKVHPDVHIYRPEGKIGMHSIASMRQFCEEVYLPPYESPWKIFMLYDAERMLNYSANALLKTFEEPALNSLIILLSSHAHALLPTILSRCRTIRFQSPNKNAAPRIKDPSRNQILSLLADGKMTSYTKLSSYASQIAHQIEEIQKAEEKAGITDIQKIPADQMNAYQKNLVEKETEGAIAMQVNQQATALLKNILSWYRDLHLLDVGGRLELLENPDFHKQLIQAYQRGEILPLEFVEEKIMNVQRSLERSTSLSYCLERLFLELQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFV5</accession>
    <name>A0A0C1HFV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JH00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386137.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73543">
        <property type="protein sequence ID" value="KIC73543"/>
        <property type="gene ID" value="DB41_JH00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1746"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="154"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="389" mass="44888" checksum="70CF1CEF5F1E7E14" modified="2015-04-01" version="1">MKLDKINSLIQELLQENSFLQAILSSPRDRILSQKITIRPFSIKNNWRLQFSHQQNQKVIHKNYSVEEGTEKILEALKHYKQALFCTVSKDYQILISKKGEATIIHKPASKKATPLLNHNRSKNYLLKENEPIPFLQELGVSSNLGKVLPGKRDKFCQINRFLEMVQDIVPYFAKDKTLQIVDFGCGKAYLTFALYYYLHFQLKYKVQITGLDLKADVVAQCQNLAKKLGFTHLHFIQGDINAYMGNEPIDLMVSLHACDTATDAALEKAVRWQAQVIMVVPCCQHELYKQVQCESLEPLLSHGILKERFSALVTEAARAKLLEILGYKTQVIEFIDMEHTPKNLLIRAIRQSSSETRHAELLKQYYQFKKTLEIKPFLEKCFIQELIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFW2</accession>
    <name>A0A0C1HFW2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">rho</name>
        <name evidence="12" type="ORF">DB41_JH00090</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386142.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73548">
        <property type="protein sequence ID" value="KIC73548"/>
        <property type="gene ID" value="DB41_JH00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1751"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="11">
        <location>
            <begin position="88"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="206"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="218"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC73548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="455" mass="50856" checksum="1C9D5591EC69A3D2" modified="2015-04-01" version="1">MDPENTHLETPYSTFEEGEENQQQHPSINTTAIVPPGETIKIAEIQRMDIDQLNAFSKKIGLKHLGSLTKSQMVFEIVKALSENPAEILYGEGVLEILPDGFGFLRSPNYNYLPSAEDIYVSPAQIRRFDLKKGDTLSGTIRPPKDKEKYFALLKVDKINGKTPEKARERILFENLTALYPSKRMVMETTKDKLSTRVLDLAAPIGKGQRGLIVAPPRTGKTIILQNIANAIAINNPEVIVIVLMIGERPEEVTDMQRIVKGEVVSSTFDEPPERHVQVAEMVIEKARRLVEHGNDVVVLLDSITRLARAYNTIEPHSGKILTGGVDANALHKPKRFFGAARNIEQGGSLTIIATALIDTGSRMDEVIFEEFKGTGNMELVLDRRLAERRIYPAIDIIKSGTRKEELLYHPNELEKVYLLRQAVADLAPNDAMNLVVGRLKKTNSNVEFLLSMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG13</accession>
    <name>A0A0C1HG13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GJ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000095">
        <property type="protein sequence ID" value="KIC76324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384650.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000095.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76324">
        <property type="protein sequence ID" value="KIC76324"/>
        <property type="gene ID" value="DB41_GJ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="112" mass="12615" checksum="68904564000BABCF" modified="2015-04-01" version="1">MMPPNSNSTNQITFRTTVSENIEDAVSGELMTRAVTLFPCGHTFNEDTVIQCLARNKLCPLDRTPIERHAPNYTVRHLAETAESHPLEEFKHEPSEEAVGHFLRGKKLVEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGM1</accession>
    <name>A0A0C1HGM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">M18 family aminopeptidase</fullName>
            <ecNumber evidence="10">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">apeB</name>
        <name evidence="11" type="ORF">DB41_IY00140</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386085.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73818">
        <property type="protein sequence ID" value="KIC73818"/>
        <property type="gene ID" value="DB41_IY00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1707"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="PTHR28570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC73818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="425" mass="47456" checksum="A4F95C511AE689D3" modified="2015-04-01" version="1">MSHSLIDDLMLLLDQAPTAWHAVDYIGRSLHAEGFTELEEAQEWELEKGKGYFLKRNGSSICAFITPQESFKKAHLIASHTDSPGFKLKPNPEFRRDNMTMLATEIYGAPLLTSWFNRDLGLAGRVFLAHSNNAIKQALVNIDSYPLIIPQLAIHLDREANEKGSYFNKQEHFSALAALDADPQQSYLLKILEDNIKDSFEYILSHDLFLYPLEKAKLIGPEMLSGYRLDSLASVHAGLTALKTSHPQKNILNLAVFWNNEEIGSKTAQGADSPFLLQVLERIAIALKLSREQFLALLPQSLCLSVDLAHALHPNYMEKHDPRHAPLMNKGPVIKYNANQRYASDAQSSASIVHLCEKHVIPYQFFSCRNDIPCGSTIGPLQASQTGITTVDIGSPQLSMHSARELIATQDHLEMCRLLAAFLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGQ6</accession>
    <name>A0A0C1HGQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FU00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384333.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76519">
        <property type="protein sequence ID" value="KIC76519"/>
        <property type="gene ID" value="DB41_FU00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="329" mass="35167" checksum="3B8D53BA1BBCA147" modified="2015-04-01" version="1">MAKKYAIGMDIGGTKIEIGLVDRYGTIHHKKRISTQANRKQEVIEQEIIQTIQEFHDLGKSFICGIGMGVPGQVSAKDGSLVFAPNLNWHNISLKKKIEDVTSLPVTITNDGRAATWGEWLNGAGKGSNNIVCVFVGTGIGGGIVNEGKVMSGYTNCAGELGHTIIQMNGPPCTCGSHGCFEAMASGWAIAKKAKEWVYKNPSQGKALLDLTEGDISATSAKLVIQAYKEGDIVAGQILNEVMEALTIGCSNMINVFNPERLILGGGVIHGLPEAVDYIKKRVKNYALKAATSTLKILPATFTEDAGTIGAGALAWHQYLTSYDKETLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH76</accession>
    <name>A0A0C1HH76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FD00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76649">
        <property type="protein sequence ID" value="KIC76649"/>
        <property type="gene ID" value="DB41_FD00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="76" mass="8743" checksum="1C149E067AC47FC5" modified="2015-04-01" version="1">MINKLILFNLSPAFRFPANPFVRVGMLLLKGKSSLSANLLVKRMLCVAGSRRKEPNHFSNFSYPKIKRTLYKKKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHA2</accession>
    <name>A0A0C1HHA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FB00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76679">
        <property type="protein sequence ID" value="KIC76679"/>
        <property type="gene ID" value="DB41_FB00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8474" checksum="B94D368993469BBC" modified="2015-04-01" version="1">MSIFYLPPRSRYFQPLLTYLKATFYLALSQWIKLYLKHFYNSSYPIFFLSIYNILLILLNHSPAQADLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHM2</accession>
    <name>A0A0C1HHM2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_EI00290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383835.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76814">
        <property type="protein sequence ID" value="KIC76814"/>
        <property type="gene ID" value="DB41_EI00290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.513"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NB-ARC" evidence="4">
        <location>
            <begin position="201"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="648"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="919" mass="104295" checksum="71F37BA7B3DEA49B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHS0</accession>
    <name>A0A0C1HHS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383722.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76854">
        <property type="protein sequence ID" value="KIC76854"/>
        <property type="gene ID" value="DB41_EC00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="7052" checksum="4FF9EDE5A7A874B8" modified="2015-04-01" version="1">MKKNETKDQLARKIAYLEFVEDQLSTELVYIDKLLKSVGFPRGLSSVKEVARDILQDHSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIG0</accession>
    <name>A0A0C1HIG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DI00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383444.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77049">
        <property type="protein sequence ID" value="KIC77049"/>
        <property type="gene ID" value="DB41_DI00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="81" mass="9523" checksum="BAF39CC69CD9F810" modified="2015-04-01" version="1">MANPHKARLTLDMDPNEHAYLKMACAKLGVTMRQFMLLATFEKMEKLEDEWLAEKAHQTLKRIESGEEKTSSWKKARERLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIT8</accession>
    <name>A0A0C1HIT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CV00170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77179">
        <property type="protein sequence ID" value="KIC77179"/>
        <property type="gene ID" value="DB41_CV00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.144"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="393" mass="44630" checksum="CC12233C7C341328" modified="2015-04-01" version="1">MEFKWKTEEKRGLTLANYSSYLLNINRLLIWKKLPGGKEYLSREEIKHLPLEKKGELLRDWIEENCKNITVLILSRAGLTYLPSEIGQLSQLRELYLNQNQLTALPAEIGQLPQLETLDLRKNQLISLPAEIGQLSQLRQLRLNQNQLTSLPVEIGRLSQLQGLDSSQNQLTSLPAEIGQLSQLQTLHLSQNQLTSLPAEIGQLSQLQTLHLSQNQLTSLPAEIGQLSQLQTLHLSQNQLTSLPAEIGQLPKLQRLELNQNQLTSLPEEIGQLSQLQELHLSENQLTSLPEEIGQLSQLQELHLSENQLTSLPEEIGQLSQLQLLYLDQNQLTSLPAEIGRLSRLRLLHLKQNQLTSLPAEIGQVPYLYMLVLAENPLKVKDIPGKIRQRFQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK81</accession>
    <name>A0A0C1HK81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74903">
        <property type="protein sequence ID" value="KIC74903"/>
        <property type="gene ID" value="DB41_IB00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8556" checksum="0678321A244A7B85" modified="2015-04-01" version="1">MDESGNNEYECSKLPALEKFKSAFLPFSSFLSFRKVPHLFLKDKKDKGGAFYLLFRVLLKFFSREFLLRRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKH4</accession>
    <name>A0A0C1HKH4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplJ</name>
        <name evidence="7" type="ORF">DB41_HY00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385537.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74978">
        <property type="protein sequence ID" value="KIC74978"/>
        <property type="gene ID" value="DB41_HY00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1399"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002363">
        <property type="entry name" value="Ribosomal_L10_eubac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01109">
        <property type="entry name" value="RIBOSOMAL_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="175" mass="19359" checksum="E75198C535FC8454" modified="2015-04-01" version="1">MREEKQLLLDEVQDHLQKNDSFLIMRYKGFTANKANEFRGDLAKQGGFIEVVRKRILVKAAKAAGLDIDVDSLEGHIGIVLAGHEPLDTAKYVYKFSQDNGKVVEVIGGRFEGQLYNAAEMEALAKLPNKDEMRAQLLGVLQAPMSETLAVMDAVLSSVVYCLDNKCKQAGEDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL46</accession>
    <name>A0A0C1HL46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75123">
        <property type="protein sequence ID" value="KIC75123"/>
        <property type="gene ID" value="DB41_HW00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="167" mass="18934" checksum="11C857FA7BEE66B8" modified="2015-04-01" version="1">MHEIIRPCKKITKKGARLALFLLVLLSSCSTSMRQWKLKCNKASSCEFTGSRLYLPPENEFSEVEVDIIKTSREKLIYLNAKGLEFQAEQKDSSGHAILPVAIHVDDQEHCYSAFLLQGNQRILLPEKACSLIISSLLDHKKVTIFVSNRSTVLTNEHFIAHYSKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL54</accession>
    <name>A0A0C1HL54_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Ribonuclease HIII</fullName>
            <shortName evidence="11">RNase HIII</shortName>
            <ecNumber evidence="5 11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">rnhC</name>
        <name evidence="14" type="ORF">DB41_HV00050</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the RNase HII family. RnhC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="5 11"/>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385453.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75133">
        <property type="protein sequence ID" value="KIC75133"/>
        <property type="gene ID" value="DB41_HV00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1348"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14796">
        <property type="entry name" value="RNAse_HIII_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00053">
        <property type="entry name" value="RNase_HIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004641">
        <property type="entry name" value="RNase_HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024568">
        <property type="entry name" value="RNase_HIII_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11858">
        <property type="entry name" value="DUF3378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037748">
        <property type="entry name" value="RnhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00716">
        <property type="entry name" value="rnhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3378" evidence="13">
        <location>
            <begin position="13"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_HII" evidence="12">
        <location>
            <begin position="99"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC75133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="304" mass="34129" checksum="2982A805B882F14E" modified="2015-04-01" version="1">MTDSSPSGKSTTFVTQLDIKIADKLMQDLINQGFEITKPLYTLFSAKKKGISCTLYQSGKLMVQGKEMASFMEFYLEPHILGNFKFSYAHLEIDITARIGIDESGKGDFFGPLCIAGVQAEGHAIHHLKTLGVKDSKSLSDQSIIKIGNKIRAEYAHHIVRINPAKYNELMIQFKNLNHLLAWGHATSIEQLANRTGCQNVIIDQFADERVVIRALQRKKMEINLTQRYRGEEDLVVAAASILARQTFVEALDQLSEKYKIEIPKGASMKTIEIGKKLVQTYGSEVLEHVAKLHFKTLDAIMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNF7</accession>
    <name>A0A0C1HNF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase, IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75848">
        <property type="protein sequence ID" value="KIC75848"/>
        <property type="gene ID" value="DB41_GZ00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="7811" checksum="114CF00EEB8BEE96" modified="2015-04-01" version="1">MDVGFSAGNMALIRRLATNIIRTFDSQRGRADARRSAAYAPNYLRGLLGKVFIKYSHQNILPRRKESLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQD8</accession>
    <name>A0A0C1HQD8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpmG</name>
        <name evidence="5" type="ORF">DB41_GG00160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76408">
        <property type="protein sequence ID" value="KIC76408"/>
        <property type="gene ID" value="DB41_GG00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="6242" checksum="5F9E85640422121D" modified="2015-04-01" version="1">MASRKREKIKLKSSASHYHYHTVKNKTNSPERMTLNKFDPVVRKHVEFKETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQW4</accession>
    <name>A0A0C1HQW4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_FO00020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000076">
        <property type="protein sequence ID" value="KIC76553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243849.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000076.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76553">
        <property type="protein sequence ID" value="KIC76553"/>
        <property type="gene ID" value="DB41_FO00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.740"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="212" mass="24078" checksum="2D1F9EA3D5A6A940" modified="2015-04-01" version="1">MSATMVSNITDKVIEVATDWQARPLQSVYPIVFFDAIHYKVKKEGKIVCKAAYTCLGIDNEGKKDVLGIWIGECEGAKFWLKVCTELQNRGVKDILIACIDGLKSLPEAIRAIFPEVKIQLCVIHMICNSIKYIPNKYAKEFAADLKGIYGAHTVEQAEQKLEKLGGKWNNKYPLAVKPWVVHWDNIKTFFEFSAPIRRMIYTTNAVEALHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR17</accession>
    <name>A0A0C1HR17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FJ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000071">
        <property type="protein sequence ID" value="KIC76588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76588">
        <property type="protein sequence ID" value="KIC76588"/>
        <property type="gene ID" value="DB41_FJ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="8395" checksum="04DB1A17C90BB72A" modified="2015-04-01" version="1" fragment="single">MKSDKIKKLDDERFRRLTGVKRGTFDKMVQILQQADAAKKIKGGRKYKLRLEDMLLMTLEYMREYRTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRB3</accession>
    <name>A0A0C1HRB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ptsI</name>
        <name evidence="20" type="ORF">DB41_FB00050</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243821.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76663">
        <property type="protein sequence ID" value="KIC76663"/>
        <property type="gene ID" value="DB41_FB00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.616"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="12"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="163"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="267"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="458"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KIC76663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="586" mass="65836" checksum="0A97C6674158A6C3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRC3</accession>
    <name>A0A0C1HRC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemin import ATP-binding protein HmuV</fullName>
            <ecNumber evidence="2">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hmuV</name>
        <name evidence="2" type="ORF">DB41_FB00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243824.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76673">
        <property type="protein sequence ID" value="KIC76673"/>
        <property type="gene ID" value="DB41_FB00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="18"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="118" mass="13359" checksum="6F2850D3A116010E" modified="2015-04-01" version="1">MLELKNLTYKVGHKTLIENISLNFIPGFIYGIIGPNGAGKSTLLKTLTGIWKATTGKVYWNHQELLSQDRTTISRTLSLVLQNPQPHFAFSVAEMVEMGTYPRHDLRKKKKKLKFSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS89</accession>
    <name>A0A0C1HS89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76958">
        <property type="protein sequence ID" value="KIC76958"/>
        <property type="gene ID" value="DB41_DP00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7175" checksum="F72189B0D605922D" modified="2015-04-01" version="1">MNELKNLVILCAQSLFETQGPWINNFFANSMGNKGSCFKEYICSPFKSSAHRENYNLFYSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSX9</accession>
    <name>A0A0C1HSX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CW00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77153">
        <property type="protein sequence ID" value="KIC77153"/>
        <property type="gene ID" value="DB41_CW00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7074" checksum="641DE84F0C1DCFF4" modified="2015-04-01" version="1">MAGRTTFLIGGNWRIVFHHTVKELKQGAKKSRFSQIRQRIHLILLAKPKLPHHLIAKTCGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JIG7</accession>
    <name>A0A0C1JIG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CA00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000246">
        <property type="protein sequence ID" value="KIC71185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71185">
        <property type="protein sequence ID" value="KIC71185"/>
        <property type="gene ID" value="DB41_CA00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="192" mass="21841" checksum="90995709715A87A7" modified="2015-04-01" version="1">MSQLTQTISGAPFTIPPQQFPPEVLTELADNCHAPLFLESELSEWADIFQAHEALVSSSQPTCDNLIFDGLTAHPITNPLLDGPLFCLQTRVKVVHTQTTPQVQRFNFAPGQWVAVWADADEDTQDFWICKIISVLHKRLHVHWWNLLMDAGLTMAQRALFQWGLFWLVALTLTPTLEFPQPPFKKYLDTCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK52</accession>
    <name>A0A0C1JK52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type III secretion integral inner membrane ring protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sctD</name>
        <name evidence="4" type="ORF">DB41_AS00190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386814.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71665">
        <property type="protein sequence ID" value="KIC71665"/>
        <property type="gene ID" value="DB41_AS00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012843">
        <property type="entry name" value="T3SS_YscD/HrpQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02500">
        <property type="entry name" value="type_III_yscD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="25"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="370"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="805" mass="89283" checksum="8166E463D8F5BC0F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JML0</accession>
    <name>A0A0C1JML0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease, major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_AI00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71801">
        <property type="protein sequence ID" value="KIC71801"/>
        <property type="gene ID" value="DB41_AI00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC71801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="394" mass="43418" checksum="549BB84A1E6E37B8" modified="2015-04-01" version="1">MTFFMIRPLIFIWLAHFLVDFMIGIWAMYKTLAHLDLFLAGTISAAGAFFGEGMQIFFGPLSDRGWRKQLICLGILFTAANTFLAYSTNYWILLLIYSITCVGSGAFHPAATSLAGTLTPHRKAMIIAIFASGGALGLASSQIIYTYFHSVLHGATAILILPAILLVLTSFYGLHGIQSFTPIHSAHEVNLKALFRMFKNRNLRLLYIAQVCNQTLFWATIFLLPDTLICKGYNAWICHGGGHLFLILGGAVMMIPAGYISDRYSPKRVILWATVAAMIAFYIFLLYPTFDNITFVALIFLLGAFFATVNSVLIAFGHLLVPESPGMVSAFLMGMAWCISEGLGQGGGGLMTRFFNEHAPVYALSILGIFFIIGIMATLWLPDLEKNEIKGQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMX6</accession>
    <name>A0A0C1JMX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_AE00010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71926">
        <property type="protein sequence ID" value="KIC71926"/>
        <property type="gene ID" value="DB41_AE00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2117"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="86"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="852"/>
            <end position="1091"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC71926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1151" mass="132962" checksum="24C214CDC944284D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP67</accession>
    <name>A0A0C1JP67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KO00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244065.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72326">
        <property type="protein sequence ID" value="KIC72326"/>
        <property type="gene ID" value="DB41_KO00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="888" mass="101082" checksum="750AC0AB3E70C879" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP73</accession>
    <name>A0A0C1JP73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JV00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73020">
        <property type="protein sequence ID" value="KIC73020"/>
        <property type="gene ID" value="DB41_JV00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="124" mass="13963" checksum="13841A0E9B2A2CCB" modified="2015-04-01" version="1">MPAEIGQLSQLQMLHLNQNQLTSLPAEIGQLSTLQWLDLNQNQLTSLPAEIGQLSQLQMLDLRENQLTALPAEIGQLSRLVRLHLNQNQLTALPAEIGQLPRLYTLELAGNPLKDIPEKIRQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQC8</accession>
    <name>A0A0C1JQC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sulfate transporter YvdB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yvdB</name>
        <name evidence="7" type="ORF">DB41_KD00210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386306.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72721">
        <property type="protein sequence ID" value="KIC72721"/>
        <property type="gene ID" value="DB41_KD00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1879"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="444"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="556" mass="60516" checksum="6E18E2A16DE57051" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVC4</accession>
    <name>A0A0C1JVC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BU00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000241">
        <property type="protein sequence ID" value="KIC71217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71217">
        <property type="protein sequence ID" value="KIC71217"/>
        <property type="gene ID" value="DB41_BU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="36" mass="4174" checksum="129DA3E739C0F6B4" modified="2015-04-01" version="1">MENAALFFLEYLPKDFPLIQACEAEKTIARSLQEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVJ5</accession>
    <name>A0A0C1JVJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HW00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385469.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75090">
        <property type="protein sequence ID" value="KIC75090"/>
        <property type="gene ID" value="DB41_HW00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="334" mass="37793" checksum="8346D45F3A61E812" modified="2015-04-01" version="1">MSIGNNVTCLEKRIDYERIYIPRICGAVGSEFIRVIPLVGGVLHYLKSRQLLSKIKRLDKNELNEKKKMKSAIRFHNLMAAAQFVPAVGSAVGFVEAAIFAVRGKPRKNKKKQLVINNLGLKINGPENGDSLALAQKELESTKQAKKKEKIKLNNNPSSAEYQASSIESAEQSKETKIKEKNSVEYTIVIIREKALHERVRKIEKEMKKQLGRVMIHKITPDQLNTDVPDHMLAFHIYFNSGQPDFPKLNRRQSEIAAKCKNNCVLVSLNRRDIAGYASKIIHSGYIKEGKLKKKSITQLCLQNPLQEKLKKSTVKALGKEMSGVFKKYIKVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWA9</accession>
    <name>A0A0C1JWA9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rplM</name>
        <name evidence="5" type="ORF">DB41_HN00120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042238997.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75380">
        <property type="protein sequence ID" value="KIC75380"/>
        <property type="gene ID" value="DB41_HN00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1289"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="148" mass="16897" checksum="135753BD27B93267" modified="2015-04-01" version="1">MTQYTNKTIMHRKEDSRPTWFILDATGKTLGRFAAEIAKILRGKHKPSFTTYSDAGDGVIVLNADKIRVTGNKEAQKEYISYTGYMSGLRRTPYRVMKARKPEYIIEHAVKGMMPHSRLANAQLKRLRVYATGKEHNLEAQKPIKANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWK6</accession>
    <name>A0A0C1JWK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proton/sodium-glutamate symport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gltP2</name>
        <name evidence="7" type="ORF">DB41_HL00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243944.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75475">
        <property type="protein sequence ID" value="KIC75475"/>
        <property type="gene ID" value="DB41_HL00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1267"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC75475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="420" mass="45938" checksum="7BCFF962EC95BDBA" modified="2015-04-01" version="1">MNALLNKSIRLNNTFLLFVAVCCGLITGYMNNEMVNTVAESFSAVFINLLKLVSLPIIFLSIVSTSSGMESARELKVLGQKVLKYTLLTTVIAASTALILFVVIDPVRTHLQEINFESVATMEKQGSYVQYLQQIIPSNVIRPFNDNNVIGVLFIALLFSLSIIALPTENRHILHAFFSSLYAAMMKMTTWIIKLMPLAIWAFITLFMRDLHEGLEIESLALYLAVVILANLVQGIIVLPLLLKFKKISPLRTVKGMLPALSIAFFTKSSNAALPMAMKCAEERVGVSRRVASFAFPLCTTINMNGCAAFILTTVLFVSMSNGMTYTPLEMILWVFLATIAAVGNAGVPMGCYFLSSAFLATLNVPLNILGVILPFYTLIDMVETALNVWSDSCVATIVDSEVSPHTASSSIVNESSLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWU4</accession>
    <name>A0A0C1JWU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">shoC2_3</name>
        <name evidence="9" type="ORF">DB41_IB00440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tonsoku family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243973.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74911">
        <property type="protein sequence ID" value="KIC74911"/>
        <property type="gene ID" value="DB41_IB00440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1476"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="189"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="791" mass="87740" checksum="9AB615006D14CE38" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWV5</accession>
    <name>A0A0C1JWV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385733.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74921">
        <property type="protein sequence ID" value="KIC74921"/>
        <property type="gene ID" value="DB41_IB00540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="441" mass="50622" checksum="398D0D75672CD135" modified="2015-04-01" version="1">MSFNVDKGAEKGRELLYSFYKDIRPNGGRAKLRNAIAIFNRLKIDKTLTLEGRLREAIQRLFDRNCSDRETKVEQAVAYLASKIDDKNQDTTKRLKKLFDKINHSEREAFISGEEKAFKKSPAYKKPWLQEKIAQSKNERFALLKANQAILEDIEGPSFIYLSPLIEKLDAFILKEENPLLWQHQAHIIKILRTLNDLNKKNLSKAEQASMREFLAGVDWGIFEPENISYLHQANIHNIEMLSDLPAGNQLLASEVKKTLNENAYKILALEEEIADKEREFDRLYGERHQLSIQSLLPPSNIHEGQATPPLQDGIHQKEEKDLADLLAVIAAMDAEEERAREEPSVERAPTREENHLTPESYDEEKALAEALAASLEEFEKLNPSKKNEGEQKAAKNFGRGPLSLLERMQLTEKKVKRGFSQLPLTFLFLPLALLKERKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXB5</accession>
    <name>A0A0C1JXB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">xseB</name>
        <name evidence="5" type="ORF">DB41_HH00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385194.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75710">
        <property type="protein sequence ID" value="KIC75710"/>
        <property type="gene ID" value="DB41_HH00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1200"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="9584" checksum="416E29A8DC0D05A8" modified="2015-04-01" version="1">MNEKELSFEAAFVRLEEILEKMNSGAISLDESLKLYEEADRLISSCQKRLLEAERKIEILVKNRNGEVVLDPDKKPLTQEFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXH7</accession>
    <name>A0A0C1JXH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lipA</name>
        <name evidence="8" type="ORF">DB41_AE00220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386667.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71947">
        <property type="protein sequence ID" value="KIC71947"/>
        <property type="gene ID" value="DB41_AE00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2139"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="81"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC71947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="326" mass="36606" checksum="A1B50CDCCB407124" modified="2015-04-01" version="1">MNPLELFDNTPRIKKKKLNILPINPDVAHQDKAVGLGRFPSWLHRKLPAGSNVWKTGNIFNQNRLHTVCEEAKCPNLMECWSKKTATFLVMGKECTRACGFCDIDFSKAPQALEADEPQRVAESVLALGLKHVVITMVARDDLLDGGAEHLSKVIEEIRRQAGEVTIEVLTSDFAGKHASLDVILKACPEIFNHNLETVRALTPRVRHRATYDNTLKVLSYVRKQGAQGLLLKSGIMVGLGESEAEVFETLKDLKTVGCDIITLGQYLQPQKNKLLVKEFITPQQFKKYEEYGYSLGIKNMYCGPFIRSSYNAEAVWKQTCKGEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXL2</accession>
    <name>A0A0C1JXL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243956.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75121">
        <property type="protein sequence ID" value="KIC75121"/>
        <property type="gene ID" value="DB41_HW00330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1389"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="273" mass="31001" checksum="4E4A0A7583A27462" modified="2015-04-01" version="1">MKKLYKFLHSISLIGLSLTLLSRLEAVEELVSSRIGRSSDSPSIAIFIPPKGWLAADQEALSSHIKYMVVGPKVQNEMPPTMNLMIEPYNGTLKDYLKSVKRINEAHGDSWKDLGMLKTKAGEASLSQVEMRSKWGGEKLMHAIIVRNKCAYVLTATAAKNEFGRFYQEFYKALRSLQIYDDILDVVKDPMKKAHLESTFAKIQKAFEAALAKAQATPSFLSQANWKEQIFHNPDFQSNHWSPFKTMLKSNYNELSNEEQNALIANYYTKLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXW5</accession>
    <name>A0A0C1JXW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72042">
        <property type="protein sequence ID" value="KIC72042"/>
        <property type="gene ID" value="DB41_AA00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7169" checksum="3809E5E9FF82017F" modified="2015-04-01" version="1">MSSYMLLSSTLSNFILNENLSLKRMQLPKGVISFLDYRDLLPLNRSISLPLMSLFRAARYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYI0</accession>
    <name>A0A0C1JYI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">frr</name>
        <name evidence="6" type="ORF">DB41_KQ00120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386483.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72247">
        <property type="protein sequence ID" value="KIC72247"/>
        <property type="gene ID" value="DB41_KQ00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2016"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="5">
        <location>
            <begin position="18"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="183" mass="20744" checksum="905E09A4B392CAA1" modified="2015-04-01" version="1">MNILEQAKSKMLVAIEHLKNDLKSIRTNRANAGMLDSIFVEIYGSSMRIKEVANVTAPEARTLLITPFDPSTTNAIGKSIEKANLGFMPIVDANSIRIKIPPMDENMRKEMVKQCHKKKEEAKISIRNIRREFNEAAKKQKTAGELTEDGLKKNEKNVQELTDKFCKEADELAEKKEKEIITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYK1</accession>
    <name>A0A0C1JYK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_KP00040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042239256.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000195.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72272">
        <property type="protein sequence ID" value="KIC72272"/>
        <property type="gene ID" value="DB41_KP00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="143" mass="16140" checksum="0A0B586A026AE231" modified="2015-04-01" version="1">MNRRFIQASIHKNIEEPTVNLTPLIDVVFVILIIFILIAPLLELDNVELAQAASGLHESSSNFVQASSPISIHVRKDNTIWFNKQMVTLEQLFTLLKDAKKRYPAAQPQLYHDRTAHFGTYQAVKNTAEKAGFTQLDVILKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ34</accession>
    <name>A0A0C1JZ34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72477">
        <property type="protein sequence ID" value="KIC72477"/>
        <property type="gene ID" value="DB41_KK00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4846" checksum="EF04A151FCA7AAC1" modified="2015-04-01" version="1">MHFISLGSDDFSAFLFFKGNIKKLKKQVKPIRILINGKATHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ35</accession>
    <name>A0A0C1JZ35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76270">
        <property type="protein sequence ID" value="KIC76270"/>
        <property type="gene ID" value="DB41_GL00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="322" mass="36842" checksum="6EEBAF5C32E4A9E7" modified="2015-04-01" version="1">MLVARLLVAMKIQHSFYELTSKQPIQSKILHSLRRGALLKVTFEEGIVGYADCHPWEELGDLPLQTQLDLLQKGKCTRLTAQSIYFAHADAKARANKRNLLEGVKIPMSHYLMAHLDASSIVNLQKAWKNGFTFFKVKLGHNLSLEKEIFAEMAHLFPNAKWRLDFNAKLNAEQFWSFMEHLPVPKTSIDYIEDPFPFIYRAWKKAFETFKVPLAADEFFKSAYGQPEAAQVLIMKPAIQRLKQVDIRQRLIVTSYLDHPLGQMSAAYIASLTTSESCGLLSHHIYQDNPFSERINNRGPFLQPVQGYGLGFDELLASQHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZC8</accession>
    <name>A0A0C1JZC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KI00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386342.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72567">
        <property type="protein sequence ID" value="KIC72567"/>
        <property type="gene ID" value="DB41_KI00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="859" mass="98312" checksum="31491BFF8B0E2191" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZJ6</accession>
    <name>A0A0C1JZJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GD00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243875.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000089.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76425">
        <property type="protein sequence ID" value="KIC76425"/>
        <property type="gene ID" value="DB41_GD00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022584">
        <property type="entry name" value="DUF2937"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11157">
        <property type="entry name" value="DUF2937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="175" mass="19784" checksum="348B8B1D17DF1250" modified="2015-04-01" version="1">MLKGLVGLIDRLFAVIGALAFSQFPLFIQQYQQNLLGHVEELKIQLQAMQSAASVTGKSLQQYIVKFLNSADTDFQLQGALMNNMVERYYTLNDSFQALQEASIYFKPFLFIKYGDWKIAKLTWQSYKIGISFTSEGAIYAGIGVIVGVAIYGLLSKLIKGLWEYYYQAEEKSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZM3</accession>
    <name>A0A0C1JZM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-amino-3-ketobutyrate coenzyme A ligase</fullName>
            <shortName evidence="1">AKB ligase</shortName>
            <ecNumber evidence="1">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">kbl</name>
        <name evidence="3" type="ORF">DB41_GC00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384514.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76445">
        <property type="protein sequence ID" value="KIC76445"/>
        <property type="gene ID" value="DB41_GC00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.841"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="111"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="208"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="239"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding; shared with dimeric partner" evidence="1">
        <location>
            <begin position="272"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="395" mass="43731" checksum="C7FD0735FF1BB655" modified="2015-04-01" version="1">MDQSFLKNLKQQIEQLKNTGLYKKESEIISPQQATITLANGNKVLNLCANNYLGLANNQQIIKAAQESYDKYGYGLSSVRFICGTQSVHHALENKISHFLKTEDTILYSSCFDANGGLFETLLGSEDAVISDALNHASIIDGIRLCKAKRLRYQNNDIEDLERQLIEAKECRFKMIATDGVFSMDGSIANLKAICDLADKYEAIVMVDDSHAVGFLGEKGGGTPEHCEVIGRVDIITGTLGKALGGASGGYTSGRKEIVEWLRQRSRPYLFSNTLAPAIAYASIKCLEIVENGQNLRKKLKDNSLYFREKMTQLGFKLLPGEHPIIPVMIGDAVLAQQMAARMLEHGVYVIGFCYPVVPQGQARIRTQMSAAHHKEELDMAIQAFENVGKEFKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZS3</accession>
    <name>A0A0C1JZS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GU00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384872.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75956">
        <property type="protein sequence ID" value="KIC75956"/>
        <property type="gene ID" value="DB41_GU00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="549" mass="61507" checksum="0F7DF4B69B4BCDC9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZS5</accession>
    <name>A0A0C1JZS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GB00100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243870.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000087.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76475">
        <property type="protein sequence ID" value="KIC76475"/>
        <property type="gene ID" value="DB41_GB00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.827"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="563" mass="63523" checksum="4F82E23BFE57651E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZW3</accession>
    <name>A0A0C1JZW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FX00190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76510">
        <property type="protein sequence ID" value="KIC76510"/>
        <property type="gene ID" value="DB41_FX00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="292" mass="33386" checksum="E4D3CC622ABEAFB1" modified="2015-04-01" version="1">MPTQGNKMHPISSATIESLPNELLLPILEACVVPSLFGVCKRWHHLLASEVMPSLYKQIGKVHVPQGNVKEQALIVDRIYKLKEKLSEAAKVNAIFRRIFTLAKSFSALEFKVQIEEKRYLTLANYSSYLVNINRLLFWKKLPGGEKYLSREEIKHVFLGKKGELFRDWIAENRENITALDLSGVGLTYLPPEICQLSKLQELDLSENQLTSLPAKIGQLLQLQELNLRENQLTSLPAEIGQLSQLQWFYLNQNQLTSLPAEIGQLSQLQTLELAENPLKDIAEKIRQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZZ1</accession>
    <name>A0A0C1JZZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FR00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000079">
        <property type="protein sequence ID" value="KIC76535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76535">
        <property type="protein sequence ID" value="KIC76535"/>
        <property type="gene ID" value="DB41_FR00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7159" checksum="AB7039262C5AFAE2" modified="2015-04-01" version="1">MLYLSGAALSEEDKQRGEEELKSLCLRCKNFTIYVSDDGQYLNTHLKETTAIMKASQAGKCILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K082</accession>
    <name>A0A0C1K082_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pkn1</name>
        <name evidence="7" type="ORF">DB41_GN00160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384792.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76106">
        <property type="protein sequence ID" value="KIC76106"/>
        <property type="gene ID" value="DB41_GN00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.977"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="14"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="633" mass="71692" checksum="596199EAC87AE3FF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0W2</accession>
    <name>A0A0C1K0W2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GG00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76406">
        <property type="protein sequence ID" value="KIC76406"/>
        <property type="gene ID" value="DB41_GG00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="7940" checksum="3FE1F4A80C75A94D" modified="2015-04-01" version="1">MKKLNLNFLMIFNTAGSMRGEGFGILLTQICLAKHSQAKTYTMIRTMLADLLRSTSSPFAFITFKYLKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Z0</accession>
    <name>A0A0C1K0Z0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384516.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76446">
        <property type="protein sequence ID" value="KIC76446"/>
        <property type="gene ID" value="DB41_GC00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="41"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="179" mass="19673" checksum="353225764AA97628" modified="2015-04-01" version="1">MLRVTPVLPEKAGPELKPLYEALEKKMGRVINIFQNMGNSPLTLKAFLALSEAAAHTHLSAKVREEIALTIGQANQCEYCVSAHTLSAKAHGIPEQEILLARKGEAQEPKTKAILKFVKIVVEKRGKVSEEDVVALKNEGVSDQELIEIVLNIAVNMFTNYFNNIIGTQVDFPEAPPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K167</accession>
    <name>A0A0C1K167_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FX00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384397.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76506">
        <property type="protein sequence ID" value="KIC76506"/>
        <property type="gene ID" value="DB41_FX00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="216" mass="24796" checksum="8DD2406B80A66400" modified="2015-04-01" version="1">MKIKNFTIILLAWVSWGCSTQDSFNPSLKYVEIAARGEGTSESKPIIYRLKVDANWIQHRPSPADPRADTRQAIIEFYIVHQDEKVSIAIHSFPSDNIYQRPSPFTYISRWKTQLHPLNPETVSLTSQAFGGYCGFLFEATGEIKGRQATIFAWILQLAPEHYHHLVAPNSPYLLKKYRQMRSDVTIKAIGPPTLMKKYRQSIIAFARSFHLIEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1C8</accession>
    <name>A0A0C1K1C8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 6">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">rpsL</name>
        <name evidence="8" type="ORF">DB41_DT00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 4 6">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 5">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383654.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76915">
        <property type="protein sequence ID" value="KIC76915"/>
        <property type="gene ID" value="DB41_DT00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.398"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 5 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="123" mass="13827" checksum="A17D7CCE7BA02431" modified="2015-04-01" version="1">MPTINQLVRQPRTPKKRRSKSPALLKCPQRRGVCLQVKTKTPKKPNSALRKVAWVRLSTGQEVIAYIGGEGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGTLDCAAVQNRKKSRSKYGAKRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1T3</accession>
    <name>A0A0C1K1T3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DUF294 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DB41_FE00010</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000067">
        <property type="protein sequence ID" value="KIC76641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76641">
        <property type="protein sequence ID" value="KIC76641"/>
        <property type="gene ID" value="DB41_FE00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF294" evidence="12">
        <location>
            <begin position="239"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="638"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="680"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="722"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="764"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="848"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="890"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="932"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="974"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1021" mass="116052" checksum="F928B3DFE745F91B" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K286</accession>
    <name>A0A0C1K286_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">rpsC</name>
        <name evidence="12" type="ORF">DB41_EI00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383805.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76786">
        <property type="protein sequence ID" value="KIC76786"/>
        <property type="gene ID" value="DB41_EI00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.484"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="155" mass="17240" checksum="E6E939C711C73A28" modified="2015-04-01" version="1">MSEKIEVTICTARPGMVIGKKGSEIEGLRGELFRLTGKEVWIEVEEIKRPDLDAKIVADAIAKQLERRIPFRRAMKKAMQSSIEAGALGIKVQCSGRIGGAEIARTEWYKEGSTPLHTLRADIDYAMGRAETTYGSIGVKVWIYRGEDNQVKEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K296</accession>
    <name>A0A0C1K296_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">rplR</name>
        <name evidence="8" type="ORF">DB41_EI00110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383819.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76796">
        <property type="protein sequence ID" value="KIC76796"/>
        <property type="gene ID" value="DB41_EI00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.494"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="123" mass="13902" checksum="F70A573845DEE7EF" modified="2015-04-01" version="1">MINITKKRHKLRIKRALRVRKKIHGTSEKPRLCVVKTNKHIQVQLIDDDNHVTIGSAATFSNEFKNTEFARKNKLSAAKLGEKIAQIAQKNNIKEIVFDRGPFKYHGILAALAEAARSAGLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2E0</accession>
    <name>A0A0C1K2E0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CV00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042243908.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77170">
        <property type="protein sequence ID" value="KIC77170"/>
        <property type="gene ID" value="DB41_CV00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="116" mass="13462" checksum="EA1E9E8F2F75F541" modified="2015-04-01" version="1">MRRVESNFQELIIKLFICVVLAGLALYSYIFKQNELTELRMAIPSLAKEVRTIHEENNRLKYEINQFESPIHLMEIMRMPEFSSLKFAYNSQVVVLPLTSPVPGKDFADLQEENGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2F0</accession>
    <name>A0A0C1K2F0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipase_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JH00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386135.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73542">
        <property type="protein sequence ID" value="KIC73542"/>
        <property type="gene ID" value="DB41_JH00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase_3" evidence="2">
        <location>
            <begin position="235"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="450" mass="51426" checksum="345D33A1A17D2D0B" modified="2015-04-01" version="1">MVSLFSWSQFSETCLKGELKSSVLDKKTLSKSLDAYLKTELKVELSPSAAKILKRYAFHKAGIKSGQQKNLSSIKACQVFENYNKLLGKIRFEFESLGFVKPIKPVGSKTMTWLSIFSSSIANKHWEPKIKANIQKLFDQAYKINLINKVVFKKDPHIELEKLISLELVGKQLAYFNPKEGERFQIPFEGRMVEYEASEIRLWMGMYAYGFKPVDENEKAPPILAFSGTRIGLSQRGFLATLAADFDPRGVGYIAYARGKKNITQWLEQNKNALVTGHSLGGALARYTAIDNPSLVHGVFSFNAPGISATYGKKWDELKTRLPHRRPHMYNFHHSEDKVPTFGQRYIGKNYQVICSVEKTVKQRFTAQYTIHNKMLFCRKIAILCKANPKPSLSLKMQRFVGIIPFIFFISLLFINRALFGLYDSRPYASVFGPLRWVWRQLITSQLAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Q3</accession>
    <name>A0A0C1K2Q3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CJ00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77295">
        <property type="protein sequence ID" value="KIC77295"/>
        <property type="gene ID" value="DB41_CJ00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4793" checksum="CC8B201201CCE7C5" modified="2015-04-01" version="1">MIFFQATLREILSIAAFYFILRKPTKQEEVSRLFKPFAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2R0</accession>
    <name>A0A0C1K2R0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cynT</name>
        <name evidence="6" type="ORF">DB41_CJ00150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383038.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77305">
        <property type="protein sequence ID" value="KIC77305"/>
        <property type="gene ID" value="DB41_CJ00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.15"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="220" mass="24526" checksum="E4CA5526CF8BEAC9" modified="2015-04-01" version="1">MKKLIQEIAHFKKNLSEEGRALFAQLALGQKPEALFIACSDSRLMPSLFASTHPGNIFVLRNIGNLIPPASSSPYDSSASAVLEFSTFSLNVSDIIVCGHSECGAMQALARGVDGHNCPHLGSWLKHGEESLNKVRKGLSINPSLSEHNQISQINVLQQMQHVISYPFIQERVEKKQLRVHGWWFDIAQADVYCYKQDLHQFVLIDEEEANLIANNLSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2S3</accession>
    <name>A0A0C1K2S3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383518.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77006">
        <property type="protein sequence ID" value="KIC77006"/>
        <property type="gene ID" value="DB41_DN00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="160" mass="18974" checksum="DD79ED1ECA751DFE" modified="2015-04-01" version="1">MFAIFQNISDNFNNYLSNLWVEKEDPIDTEARIECERLRPEIEELKQKTYLLDTFINERPELKNECLKYYHKYKHFFIKNIRGCGRTDFDLGNPVDQLNILAVEKLDLEYELNQRIDFLTSFKEVYALFEKHVLEAQKAAKGAGNTFPLLLTQVLENEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K327</accession>
    <name>A0A0C1K327_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DB00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77096">
        <property type="protein sequence ID" value="KIC77096"/>
        <property type="gene ID" value="DB41_DB00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8135" checksum="17FAAE6F768AF76A" modified="2015-04-01" version="1">MMIKFLKLRLSNNQLTLILIEIQRLSLRQYLWLCNKQLTTLPTSIGQLSKLQTLYLSDNELTALRAEIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K392</accession>
    <name>A0A0C1K392_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrogen regulatory protein</fullName>
            <ecNumber evidence="3">2.7.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ptsN</name>
        <name evidence="3" type="ORF">DB41_CP00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EUO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77221">
        <property type="protein sequence ID" value="KIC77221"/>
        <property type="gene ID" value="DB41_CP00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.81"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="2">
        <location>
            <begin position="83"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="231" mass="26466" checksum="8E85B7F946239DE3" modified="2015-04-01" version="1">MRVDLKIKDVADLLNVSEKTIRRWLTEGKIPSYQINQQHLFNRNEIEDWVLSQKIPEASFDHPTAIPDPSPIKGGIKQFSLYRALHKGDVLIDIMGDTKEEVIRQTMQRMAKSLNLDAEGISHLLLDREKLQPTALNNGIGIPHTRDFLLNAHYDVVVVAYSKNPIDYGALDGKPVHTLFFLFACDDKRHLHLLAKIAHLVNHPNTLEFLQSKPPKEEFLNYIKNFESSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3A1</accession>
    <name>A0A0C1K3A1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">nadE</name>
        <name evidence="9" type="ORF">DB41_CO00100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383101.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77241">
        <property type="protein sequence ID" value="KIC77241"/>
        <property type="gene ID" value="DB41_CO00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.44"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="293"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="516"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="545" mass="61024" checksum="B2F0DEA239C39C02" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5J2</accession>
    <name>A0A0C1K5J2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IJ00230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74552">
        <property type="protein sequence ID" value="KIC74552"/>
        <property type="gene ID" value="DB41_IJ00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="626" mass="71937" checksum="4F8FD7EC90A3AB3D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7H1</accession>
    <name>A0A0C1K7H1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0337 protein YjbJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yjbJ</name>
        <name evidence="3" type="ORF">DB41_HW00190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385490.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75107">
        <property type="protein sequence ID" value="KIC75107"/>
        <property type="gene ID" value="DB41_HW00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026042">
        <property type="entry name" value="YjbJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039008">
        <property type="entry name" value="YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="2">
        <location>
            <begin position="6"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8346" checksum="2478814743907E86" modified="2015-04-01" version="1">MNKEFFEGSWHELKGKIKEKWGKLTDDDLLRIDGSWEQMLGSLEKNYGYKKDQAEKELSKWKNESTHLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K837</accession>
    <name>A0A0C1K837_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">queE</name>
        <name evidence="7" type="ORF">DB41_HQ00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000127">
        <property type="protein sequence ID" value="KIC75342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385415.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000127.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75342">
        <property type="protein sequence ID" value="KIC75342"/>
        <property type="gene ID" value="DB41_HQ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1323"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="38"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC75342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="215" mass="24334" checksum="5176F99260733E6D" modified="2015-04-01" version="1">MNSLNIIEIFRSIQGETSLAGLPTTFIRLAACNLRCSWCDTTYSFGRGVSYTLENIFSKVASFGCQYVCVTGGEPLLQANVIPLMDQLCQAGYIVSLETGGSLSTQKVNANVRIILDIKCPGSQMSNKNLWDNLNHLRFHDQIKFVISNREDYDYAKMVCSQYQLFKKVSEILFSPVFEVLPSQTLVNWILEDQLAVRLNLQIHKFIWPPHTRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9A5</accession>
    <name>A0A0C1K9A5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HH00350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243938.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75742">
        <property type="protein sequence ID" value="KIC75742"/>
        <property type="gene ID" value="DB41_HH00350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1234"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="224" mass="25603" checksum="E408EB7328F06C77" modified="2015-04-01" version="1">MNPSSSITIEHLPNEILTPILKACASPSLFSVCGRWYHLLANEVMPSLYKQIGKVHVPQGDVNEQVLALDRIYKLEEELSKKAKVNAIFRQIFTLARSLSPLEFKEGLKENRYFTLANYSSYLLNINRLLMWKKLPRGEKYLNRETIKYLPLEKKGGLFSNWIKRHGKKLTKLDLQGIGLTFLPPEVGQLSNLRDLELSDNQLTTLPAEIGQLLQLQKIILSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9V9</accession>
    <name>A0A0C1K9V9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">priA</name>
        <name evidence="11" type="ORF">DB41_GW00090</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384922.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75937">
        <property type="protein sequence ID" value="KIC75937"/>
        <property type="gene ID" value="DB41_GW00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1051"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="217"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="742" mass="84500" checksum="1220A9FCA9F7AA76" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAI3</accession>
    <name>A0A0C1KAI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GN00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243899.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76097">
        <property type="protein sequence ID" value="KIC76097"/>
        <property type="gene ID" value="DB41_GN00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.968"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="102" mass="11697" checksum="13DA335C20BA063D" modified="2015-04-01" version="1">MDKKKVKSWLLAKKGELFKDPIKRHGNDIKRLILKGRVLTFLPPEIGQLSYLQELNLNSNQLTSFPAEIGQLSQLQELYLIDNTLSSYFLCNPVLCIIPLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBB3</accession>
    <name>A0A0C1KBB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GC00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384518.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76447">
        <property type="protein sequence ID" value="KIC76447"/>
        <property type="gene ID" value="DB41_GC00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="23528" checksum="D6F901CF22025837" modified="2015-04-01" version="1">MKSSLYKQVIFDLGGVLFYWNPKEVSRLLKEKDPDFPLHIEKIIYTQTWTDLDAGIISLEEAMQQLSTCYPRQYIERFVSLSLEKLVPLEKGISLLKQVQAQGKQTFILSNISGEFFKKISIYNGLLDSFDGAFFSYEIHTVKPHKKIYQFLLNKYFLKPEECLFIDDSLANVTTAQKMDIDAIVCQEHQHVHDELLRLKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBL0</accession>
    <name>A0A0C1KBL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine/putrescine-binding periplasmic protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">potD-A</name>
        <name evidence="2" type="ORF">DB41_FU00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384345.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76527">
        <property type="protein sequence ID" value="KIC76527"/>
        <property type="gene ID" value="DB41_FU00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.771"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Spermidine-binding" evidence="1">
        <location>
            <begin position="166"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR019574-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="345" mass="39430" checksum="2FCA6ABC2A93A5DC" modified="2015-04-01" version="1">MRKWLFFIIAFVYLAILVTTCSTPENELHLYIWADYIKPELIEKFEQEHNCRIVYDTFDSNESMYARLKLGVTGYDVIFPSGYTYELMLQQKMLNPIPISSLSYLKNLTPHYTPEKFEEGSVIYGVPFAMSYSGIAYRKDKIKVEDQSWGIFGRLDMRGRMTMLNDLRETLGAALKYLGFSANSTNREEINQAVDQLLVWKKNLAKFESEQNKHGIASAEYIVSQGYNGDMLQVMRENSHVGFFIPQEGSIISLDYAVVPQHAPNPSLAHAFINFLLEGAVAAENMQFTCFPSPNQAAYALLPKELQENPSLFPPQAILDKSEVLRYLGKDGELYNQAWDKVKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBS3</accession>
    <name>A0A0C1KBS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FL00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000073">
        <property type="protein sequence ID" value="KIC76577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76577">
        <property type="protein sequence ID" value="KIC76577"/>
        <property type="gene ID" value="DB41_FL00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="223" mass="25637" checksum="4D26E94B5379E1EC" modified="2015-04-01" version="1">MTFAPTGEKLSETTTHYNHFHKIAEVDAAGEFTHYQYDAAGRLASIVKNEAKTVYQYDACQRLAKTLEYFGPEEKDYIASVKEYDAKDRLIEERTEDAEGQVLTKIGYLYNEQDQPIQTISYHHSKPVITFTHYNAYGDVDTVIDPQGHKTRTLFYYLHLNQEGQYVYAKETIDAIGQFFFRNMIAAGMFALKFVATLWALSCKNVSFFMMQKGFAVNKLSMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCC1</accession>
    <name>A0A0C1KCC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_EP00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000055">
        <property type="protein sequence ID" value="KIC76747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76747">
        <property type="protein sequence ID" value="KIC76747"/>
        <property type="gene ID" value="DB41_EP00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.549"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="21"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="385"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="427"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="511"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="553"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="595"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="637"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="679"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="763"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="805"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="847"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="931"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="973"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1015"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1099"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1141"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1183"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1225"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1267"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1309"/>
            <end position="1342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1371" mass="155454" checksum="1FE5FCF7A210B732" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCK4</accession>
    <name>A0A0C1KCK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76812">
        <property type="protein sequence ID" value="KIC76812"/>
        <property type="gene ID" value="DB41_EI00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.510"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045468">
        <property type="entry name" value="DUF6496"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20106">
        <property type="entry name" value="DUF6496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="5734" checksum="C633D44127A4AEA5" modified="2015-04-01" version="1">MPLKKGTSRKTISENIRTEVHHGKPQKQAVAIALNEARRSGAKIPKKGKNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCV2</accession>
    <name>A0A0C1KCV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative cadmium/zinc-transporting ATPase HMA1</fullName>
            <ecNumber evidence="7">3.6.3.3</ecNumber>
            <ecNumber evidence="7">3.6.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hma1</name>
        <name evidence="7" type="ORF">DB41_DW00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.3" evidence="7"/>
    <dbReference type="EC" id="3.6.3.5" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383686.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76897">
        <property type="protein sequence ID" value="KIC76897"/>
        <property type="gene ID" value="DB41_DW00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.414"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="617"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="662" mass="70775" checksum="34108849B8412F47" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD01</accession>
    <name>A0A0C1KD01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iscS</name>
        <name evidence="3" type="ORF">DB41_DS00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383625.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76932">
        <property type="protein sequence ID" value="KIC76932"/>
        <property type="gene ID" value="DB41_DS00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.386"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="2">
        <location>
            <begin position="4"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="388" mass="42503" checksum="167ACFFBDAFE9BE0" modified="2015-04-01" version="1">MPSIYFDNSTTTRPSEKTVSKMLPFFYRQWGAPLAPHHLGQELLPAIEESLNYIYKLLNIKKTDAFVFTSSGAEAVNHVFYSVYHDVTRLTGKNQFITSNIEEAPATMLINRLEDWTCVGKILKANLSGYISPAAVADAITPRTALVSLAWANGLTGVINPVAEIAAVCQEKGVLLHIDATHVLGKLFFQLEDINPAFLTFNGDHLHAPKGTGGLYIKEGIKCSSFIVGGMDQGGRRAGTLNVPALVGLGEASCEVLEAQDLMCTEVARLRDLFETQITSSIPHTQVFFQDQNRLPHISAIAFAGINSEALLFALNRKGVYASMGGGNFQQLKLILMASAMDETLASSTLSFSFCKDNSEDEVMHAVEIIKECVLKLRKLSSHLYFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD57</accession>
    <name>A0A0C1KD57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383579.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76972">
        <property type="protein sequence ID" value="KIC76972"/>
        <property type="gene ID" value="DB41_DP00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="313" mass="36439" checksum="112D72A3758BBB0A" modified="2015-04-01" version="1">MNIEQRALFNSLRINWLLNPNTQVQPWQVEDYRLLSHEELFDRLRQKDMALDKISLLALAQDVDSPEELCEGLVADLNLEASEQDQIYLVVFELWRRFVNEKPCLSIFCDELDHQIFAYDQGKCAYPADIQDAMANLEMILGKHADEGADPLKIFESVSQGCAHDLETFLYDYIAEQIDGHHYPYAADLLESFGPYCKDVAWFDFLRARLFYHSDPENSDKMILHIIQSIKKAQDLDLSLEVLTFLSNGGNPELFRLLVRQTFPMLETEEDFQELLTICADYYHLLDQEQEEQKNSKNFKAKSFSCFRKSNPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDA0</accession>
    <name>A0A0C1KDA0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ppiB</name>
        <name evidence="7" type="ORF">DB41_DN00180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76997">
        <property type="protein sequence ID" value="KIC76997"/>
        <property type="gene ID" value="DB41_DN00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.308"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="29"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="185" mass="20908" checksum="39877834EE98B921" modified="2015-04-01" version="1">MQKWMLFLSLAFFQLFAHLAIYGESYQPKHPVVVFETTQGNFEVTLFPDLAPKAVENFLTHAKENYYNGTSFHRVIKGFMIQGGDPEGNGTGGQSIWGKPFADEFHPDRHFDHPGILAMANRGPHTNGSQFFITTAKTPWLDQKHTIFGEVTKGYEIVQKIEGAQTDAQNRPLVAQKIIKISLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDT0</accession>
    <name>A0A0C1KDT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CY00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000015">
        <property type="protein sequence ID" value="KIC77132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77132">
        <property type="protein sequence ID" value="KIC77132"/>
        <property type="gene ID" value="DB41_CY00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="10001" checksum="FBFA967B87C9D5DD" modified="2015-04-01" version="1">MRVGSFRRNFAAIIEDHLLKTAGDGFKKKLEGRVFSFRKVGYQRAGEQDRYSAMNKIAKLGNVSQGQWVLTQGIRSNIRLYLKQTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE34</accession>
    <name>A0A0C1KE34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable endonuclease 4</fullName>
            <ecNumber evidence="7">3.1.21.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Endodeoxyribonuclease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Endonuclease IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">nfo</name>
        <name evidence="9" type="ORF">DB41_CO00060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.</text>
            <dbReference type="EC" id="3.1.21.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 3 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.2" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383093.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77237">
        <property type="protein sequence ID" value="KIC77237"/>
        <property type="gene ID" value="DB41_CO00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.39"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="8">
        <location>
            <begin position="27"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="287" mass="32269" checksum="6713C77F9713B8CD" modified="2015-04-01" version="1">MTIKAENLLIGAHTSAAGGLHHALYEGREIGATTIQLFTTNQRQWRAKPLMPDIIDAWHAALKETHLQKIMSHASYMINLGAPDPENLRKSREAFGLEIERCLKLNISFLNFHPGAAIDKDPQECLDRIVESLLTYEPLLQGDGTRLLLENTAGQGSAVGWRFEELAYIIGKVENRLPIGVCLDTCHLFAAGYDLGSTLACEETLKKFDQLVGFKHLYAFHLNDSLKGLGSRVDRHQYLGKGLIGIDCFKFLMNHPQTQAMPKYLETPKDPLIWKVEIQMLRDFVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE40</accession>
    <name>A0A0C1KE40_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 25">Na(+)-translocating NADH-quinone reductase subunit F</fullName>
            <shortName evidence="25">Na(+)-NQR subunit F</shortName>
            <shortName evidence="25">Na(+)-translocating NQR subunit F</shortName>
            <ecNumber evidence="6 25">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="24 25">NQR complex subunit F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23 25">NQR-1 subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25 28" type="primary">nqrF</name>
        <name evidence="28" type="ORF">DB41_CO00110</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28 29">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 25">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 25">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="25">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="25">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 25">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 25">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="25">Cell membrane</location>
            <topology evidence="25">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 25">Belongs to the NqrF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="6 25"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383103.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77242">
        <property type="protein sequence ID" value="KIC77242"/>
        <property type="gene ID" value="DB41_CO00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.45"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00430">
        <property type="entry name" value="NqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010205">
        <property type="entry name" value="NqrF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000044">
        <property type="entry name" value="Cis_Diol_DH_RD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01941">
        <property type="entry name" value="nqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 25" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 25" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 25" id="KW-0274">FAD</keyword>
    <keyword evidence="10 25" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="19 25" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 25" id="KW-0408">Iron</keyword>
    <keyword evidence="16 25" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="21 25" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 25" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17 25" id="KW-0520">NAD</keyword>
    <keyword evidence="28" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18 25" id="KW-0915">Sodium</keyword>
    <keyword evidence="22 25" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="14 25" id="KW-1278">Translocase</keyword>
    <keyword evidence="25" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="25" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="25" id="KW-0813">Transport</keyword>
    <keyword evidence="20 25" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="26">
        <location>
            <begin position="49"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="27">
        <location>
            <begin position="146"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00030032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00030787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="KIC77242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="443" mass="49203" checksum="60FE204D9A8882D3" modified="2015-04-01" version="1">MDSLFNFTIASLGGIDIFLVAYAIVAFVMIGTGLAGIILFTRAKFVSSEACTIKVNEDPSLTKTVAGGSTLLLALSSNGIPIPSPCGGKATCKQCRVQILEGANQPLETDKGTFTKKQLKEGWRLSCQAKVKNDLHLHVEADALGVKEWSATVISNQNVATFIKELIVELPQGEEVPYRSGGYLQFHVPPFQANTESWKNTMHPQYHEDWEKFGLVGHSLDFSSLPTGSEEVIRAYSMASYPAEGRTLRFNIRIATPPFIAGKLAEKIPWGICSSYTFNLKAGDKIKLSGPYGESFMIQDSRELIFLIGGAGSSFGRSHIMHLFKTEQTHRKVTLWYGARSLKENIYQADYEQLEKEFSNFHYHLVLSEPLPSDLEAGWPANDPTKTNYLFKAFEMGQLKFMEAPEECLFYVCGPPLHNKSVLKLLEDYGVPRESIVLDDFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1J0</accession>
    <name>A0A0C1H1J0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71564">
        <property type="protein sequence ID" value="KIC71564"/>
        <property type="gene ID" value="DB41_AV00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5435" checksum="A230E5BC6591701E" modified="2015-04-01" version="1">MLNGPLLLKKQQALKAVLYFLRFKGAAKKLLLFLLNRLFILSFKIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1U8</accession>
    <name>A0A0C1H1U8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AS00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386812.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71664">
        <property type="protein sequence ID" value="KIC71664"/>
        <property type="gene ID" value="DB41_AS00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035336">
        <property type="entry name" value="DUF5398"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17376">
        <property type="entry name" value="DUF5398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="79" mass="9388" checksum="60E202059C01D339" modified="2015-04-01" version="1">MFGLEKQKKKKGEEFTFELEKELKAFNSHQDYKKKVEERIQDIRSLLRKGENKDEFDKLGVLLHGYTSLLKVMSRLSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3Y8</accession>
    <name>A0A0C1H3Y8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ATP:guanido phosphotransferase</fullName>
            <ecNumber evidence="7">2.7.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">karG</name>
        <name evidence="7" type="ORF">DB41_KQ00140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP:guanido phosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.-" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72249">
        <property type="protein sequence ID" value="KIC72249"/>
        <property type="gene ID" value="DB41_KQ00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004111">
        <property type="term" value="F:creatine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046314">
        <property type="term" value="P:phosphocreatine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000749">
        <property type="entry name" value="ATP-guanido_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022414">
        <property type="entry name" value="ATP-guanido_PTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11547">
        <property type="entry name" value="PTHR11547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00217">
        <property type="entry name" value="ATP-gua_Ptrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51510">
        <property type="entry name" value="PHOSPHAGEN_KINASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphagen kinase C-terminal" evidence="6">
        <location>
            <begin position="24"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="27"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="175"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="206"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="357" mass="40533" checksum="0C077BC8923C104B" modified="2015-04-01" version="1">MANNNKSNVIINQKKLWQNNDNDIWLASILHLHRNLEKFNFPGKLSTERRKQVVSVLSKEILSLGLLETATLIRAEEMEPFEKEFLGEHFWSNDNFIQAHLGEAFIIDASGQFLASFNIRNHLHLQLIECKGELEKAWNKLLKIETTIGQNISFAYNAKYGFLTADIGSCGTALLVSIYLQLPALVHTGKMEEIVEKNKEESIACFGLRGSPKEIIGDLLVVQNNYTLGVTEESIISNLNAFATKMVVEENTARNQIRASSDPYIKDKISRAFGILTHSYQIDAIEALNAISLLKLGIEMGWVEGISRQSINQLFFNCRRSHLLAEFHEKTHLPQEEIVHKRAEFIHKALLQAHLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4V0</accession>
    <name>A0A0C1H4V0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KJ00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244050.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72534">
        <property type="protein sequence ID" value="KIC72534"/>
        <property type="gene ID" value="DB41_KJ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1926"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070569">
        <property type="term" value="F:uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="PTHR11952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="736" mass="83189" checksum="6C1CAB3CD0BB83FC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5E1</accession>
    <name>A0A0C1H5E1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KE00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000186">
        <property type="protein sequence ID" value="KIC72684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72684">
        <property type="protein sequence ID" value="KIC72684"/>
        <property type="gene ID" value="DB41_KE00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1884"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="269" mass="30087" checksum="AEA48772390EE149" modified="2015-04-01" version="1">MDLSKAGLTYLPTEIGQLSQLQKLNLIENQLTTLPTEIRQLSQLQRIGLSQNQLTALPAEIGLLSQLQVLYLNQNQLTALPTEIRQLSQLQTFDLSQNQLTNLPAEIGQLSELQWLNLNQNQLSSLPGEIGQLSELQELYLNNNQLTSLPAEIGQLSQLRALNLNQNQLTSLPAEIGQLPQLQTLSLENNQLTSLPQEIGQLPQLQLLYLNNNQLTSLPTEIERLSQLRALYLNNNQLTSLPAEIGQLSKLQTLELAENPLKDIAEKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H7Q7</accession>
    <name>A0A0C1H7Q7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_JJ00060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000166">
        <property type="protein sequence ID" value="KIC73474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386154.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000166.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73474">
        <property type="protein sequence ID" value="KIC73474"/>
        <property type="gene ID" value="DB41_JJ00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC73474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="172" mass="19726" checksum="2D71B459672A4FE5" modified="2015-04-01" version="1">MPNYTIRHLAETATSHPLEKEPKQEPNEEAEKHFLRGKEYVEQEDHEAAIEALLQALHLSPNYEKAQTYLEFCLKRSSHSSSVHPSSSLSQPISRPLSEKPQKKILSSLGHSSEGYTELLFNLLEEPQIQGNPALKKMLENQLEELMSQESEELTKKEEISYKWTKNLLGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8X5</accession>
    <name>A0A0C1H8X5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IY00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244009.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73814">
        <property type="protein sequence ID" value="KIC73814"/>
        <property type="gene ID" value="DB41_IY00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1703"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102420">
        <property type="term" value="F:sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016222">
        <property type="entry name" value="G3P_O-acylTrfase_chlp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35695">
        <property type="entry name" value="PTHR35695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000431">
        <property type="entry name" value="Glycerol-3-P_O-acyltransfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="109"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="343" mass="39574" checksum="AE9C716838E00C08" modified="2015-04-01" version="1">MGYMKLLKSLKSEEALNSKQYEILEGFYLSFTQAVTENNKPMSAYEPIITQYLQFVIQENQQPYAFEPYHRAIRTPYDYYRLGLEMMRPLIAFAHSKIHHARYIEEIETHLANQENVILLANHQIEPDPQVICLMLEKDHTRLAEEMIFVAGHRVITDPLAIPFSKGCNLLCIFSKKHVENPPEKKQEKLLYNQRVMHQMSQLLAEGGKCIYVAPSGGRDRANINTGQVEIAPFDAHSIEMFWLMAQHSGKKAHFYPLSLSTYDLLPPPQSVEKELGERRQAKCAPVHLSFGQEIDMINFPGSQHLDKKTRRIARAQYIWELVMQQYCLTRSCAPLHPLQASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9M0</accession>
    <name>A0A0C1H9M0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386874.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71563">
        <property type="protein sequence ID" value="KIC71563"/>
        <property type="gene ID" value="DB41_AV00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="16274" checksum="DF252C5A4A3D98AC" modified="2015-04-01" version="1">MSNADIDEQLNKLLSIKEKSYTFTIGSNLHDKLEKHLFSLKAINKKCSKGKWVYEAIAEKLKLENVGDLSKQRRIQVFLDDNISNEIEKRIQIFKKVYSSYSKKQWILEAIHEKLDRELKLIKEEFKKTYATEMDSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9Z6</accession>
    <name>A0A0C1H9Z6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71658">
        <property type="protein sequence ID" value="KIC71658"/>
        <property type="gene ID" value="DB41_AS00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2215"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="334" mass="37465" checksum="823F86D0A1CB7A77" modified="2015-04-01" version="1">MKKTEKELANMYNFKITGDQNKDNVTISRASNSKPSGASSRDFQKVLSEKERRQKEEEEDSKKAKTVDPSFETEALLLAEEIPSPKQPSLFDLSKEVVKKKNESETSEVAKMVSSDELPMESPNGLYKNLALKEKASRSKTGEGMWEESQKDKLEAHEDKKPIRFSQEAGDLSHVNPLALNVSSSSQSHNQNLETNMPSQKLTTQQLIDAIVKAITTIDSQGKTDTIVTLKHPPMFAGANLVLTSYESAKGEFNIRFENLTQGAKSFMDMQQNQQSLLSSLNEKGYTVHMVVATTQIETPPFNPAAPQQPPRDGQQEEQQKRQDNRKQKEDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA09</accession>
    <name>A0A0C1HA09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AR00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000214">
        <property type="protein sequence ID" value="KIC71673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71673">
        <property type="protein sequence ID" value="KIC71673"/>
        <property type="gene ID" value="DB41_AR00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="5302" checksum="5AA17BDE3071E3DB" modified="2015-04-01" version="1">MIEKDIDLLISIFCDVEDFCKQFEPEWRKILVEPPKTFNWKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB62</accession>
    <name>A0A0C1HB62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_II00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74629">
        <property type="protein sequence ID" value="KIC74629"/>
        <property type="gene ID" value="DB41_II00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="77" mass="8967" checksum="3AE864A54151A64E" modified="2015-04-01" version="1" fragment="single">MLNNDYLTKLINLEGVKFKDIYIQEDTVRILITPINPTLLCPYCSQPTFKLVDIKSKAYRDVDLAGRACYIEIDLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBY5</accession>
    <name>A0A0C1HBY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">uvrC</name>
        <name evidence="10" type="ORF">DB41_IB00620</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385746.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74929">
        <property type="protein sequence ID" value="KIC74929"/>
        <property type="gene ID" value="DB41_IB00620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1498"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="8">
        <location>
            <begin position="13"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="7">
        <location>
            <begin position="204"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="9">
        <location>
            <begin position="270"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="609" mass="70096" checksum="F0676DEF5D334EE4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBY8</accession>
    <name>A0A0C1HBY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-glucuronate 4-epimerase 4</fullName>
            <ecNumber evidence="2">5.1.3.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gae4</name>
        <name evidence="2" type="ORF">DB41_KO00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.6" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386438.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72318">
        <property type="protein sequence ID" value="KIC72318"/>
        <property type="gene ID" value="DB41_KO00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1985"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050378">
        <property type="term" value="F:UDP-glucuronate 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="320" mass="36306" checksum="67C13590F22E0D9D" modified="2015-04-01" version="1">MKHVLITGAAGFIGFHLAKALKKRGDHVIGIDNFNDYYDPLLKRARAKELEKQGIALLEGDITDANFLYELIAHHQISHLIHLAAQAGVRYSLENPQAYVKANIEGFLNVLETCRQFPGLQLVYASSSSVYGLNQKIPFSIEDRTDHQASLYGVTKKANELMASTYYHLYRVPITGLRFFTVYGPWGRPDMAYFQFTKSILEGKPIHIFNHGKMRRDFTYIDDIVQGIKSSIDREGKNEIFNLGNHQPVDLLKMVEIIEETVGKKAEKIFVPMQPGDVLETYADIQASQQILGFLPKTTLEDGIPQFVKWYLNYCSTKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC55</accession>
    <name>A0A0C1HC55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">infA</name>
        <name evidence="5" type="ORF">DB41_HY00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385545.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74984">
        <property type="protein sequence ID" value="KIC74984"/>
        <property type="gene ID" value="DB41_HY00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1405"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8233" checksum="78158BC3200A5055" modified="2015-04-01" version="1">MAKEDTIKLDGTVEELLPNMTFRVSLQNGLKVIAHLCGKMRMKNIRVLVGDVVTVEMSPYDLTKARIIFRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC83</accession>
    <name>A0A0C1HC83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75009">
        <property type="protein sequence ID" value="KIC75009"/>
        <property type="gene ID" value="DB41_HY00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="9236" checksum="7B4BD3CEDAB48B24" modified="2015-04-01" version="1">MLEILMLRKQCKSGSVVNRKNSYLQAFFVLQMPVESRLKLGLSCDRLQKKPTDYLSRPWLMKLCKEGLRIVPWSFFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCK5</accession>
    <name>A0A0C1HCK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KJ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386363.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72528">
        <property type="protein sequence ID" value="KIC72528"/>
        <property type="gene ID" value="DB41_KJ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1920"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="26908" checksum="BC2237B5173BA44C" modified="2015-04-01" version="1">MTLTVFQQEVENLSGIKLKLKINDNRSTMLSVRWETDCTRVSLHRMFLEAPQNVLDSLACYIRQEHKMISSEIKIFMENSLKKLDYSHTLDRSKLSCQGKVYNLQHLYDELNDQYFEGKVKLFITWFGKHAQLNKRSVTFGLYHHPLKLIKINRLLDNTNIPKYVINYVIFHEILHHICPSYMDEKGLHRIHSKEFKAKEESYEHFDIAHQWIKKHRVHLFAHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCP4</accession>
    <name>A0A0C1HCP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KI00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386349.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72573">
        <property type="protein sequence ID" value="KIC72573"/>
        <property type="gene ID" value="DB41_KI00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="153" mass="17474" checksum="C750F92DB9BB7A59" modified="2015-04-01" version="1">MLNLIYFFPVCGAVIGIVSVLMTCFLLRRKLKRSQHDLVTQLGKTLNQTDLLPNAQELLEDNLQEIIEDLKNQIPMGAMLFTKAVSGKVQGLVKENLLKRMPALKEKAFIYLSSRIEVEKLLLPLVYSELYTLLFYGALMGFLVSLFTLMWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD07</accession>
    <name>A0A0C1HD07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KF00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000187">
        <property type="protein sequence ID" value="KIC72643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72643">
        <property type="protein sequence ID" value="KIC72643"/>
        <property type="gene ID" value="DB41_KF00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="192" mass="21918" checksum="4A0D5297B320981F" modified="2015-04-01" version="1" fragment="single">QVMMLWNNGSKREYHVWNAENGTKIYEGELEPLPSDKYLKKNQVKLTVCDYNQSQLVVGFSDGAIACYEPTSGKFIREKLMTFRAIRFLQVGKEYCITAANPPYFFEINSLSLTDLARKDLHFKRPGEAREIISAIRTFYSSKGSLASCDTEGWLEQWKFDGIISQKKGSISQSNDKNERPFAFGLPSFLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD80</accession>
    <name>A0A0C1HD80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Omp85 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HN00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385346.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75369">
        <property type="protein sequence ID" value="KIC75369"/>
        <property type="gene ID" value="DB41_HN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Omp85" evidence="2">
        <location>
            <begin position="243"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="535" mass="60735" checksum="CDAA11AD79F4B220" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDJ7</accession>
    <name>A0A0C1HDJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KA00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000183">
        <property type="protein sequence ID" value="KIC72838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72838">
        <property type="protein sequence ID" value="KIC72838"/>
        <property type="gene ID" value="DB41_KA00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5447" checksum="BC0669D51FA86972" modified="2015-04-01" version="1">MAYCKLEFLKIKTLLNHFALKYKLILKANQMAYQELQNLQRSSMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE85</accession>
    <name>A0A0C1HE85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">acpS</name>
        <name evidence="10" type="ORF">DB41_HH00320</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385238.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75739">
        <property type="protein sequence ID" value="KIC75739"/>
        <property type="gene ID" value="DB41_HH00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1231"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="13766" checksum="647CF00283DC65B8" modified="2015-04-01" version="1">MIRGIGIDIIEVARIEANIHKYGQKFLDKVFTEEEQKYCQSFRQSSKNFAGRFAAKEAVVKALGTGLTGGLSWTDLSILNNEQGKPYLALTDTFKKHFKNPLIHISISHCQEYATATAIWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HED1</accession>
    <name>A0A0C1HED1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">rnhB</name>
        <name evidence="14" type="ORF">DB41_HE00050</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243925.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75789">
        <property type="protein sequence ID" value="KIC75789"/>
        <property type="gene ID" value="DB41_HE00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1139"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="34"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC75789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="227" mass="25097" checksum="5EA70A865255D55B" modified="2015-04-01" version="1">MSELKKIGKRETKRLLSLTTFEEEARQQGYQIIAGIDEAGRGPLAGPVVAAACIIPVGLLIPEVNDSKQLSSDKRTELYNIITRHDDIHYGIGVIDSSTIDKINIYQATIAAMLMAVAQLSLEPHFLLVDGLKLPHPSIPTQKIIKGDTKSQSIAAASIIAKVTRDRLMIEYHQQWPLYGFDQHKGYGTAKHLEALNVHGVCPIHRQSFGPVRHQLGIKNAQFSLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEK6</accession>
    <name>A0A0C1HEK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">engD</name>
        <name evidence="4" type="synonym">ychF</name>
        <name evidence="7" type="ORF">DB41_GZ00380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384989.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75874">
        <property type="protein sequence ID" value="KIC75874"/>
        <property type="gene ID" value="DB41_GZ00380"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1103"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="6"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="282"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC75874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="366" mass="40378" checksum="74464E69313D174F" modified="2015-04-01" version="1">MAAGRLSCGIVGLPNVGKSTLFNALTSNQAPASNYPFCTIDPNVGVVEVQDTRLHVLSEISHSNKIICATMEFVDIAGLVAGASQGEGLGNKFLANIRETDAIVHVVRCFDSSDIVHVSGQTDPIRDIEVINLELCLADLQMIENAIPRVEKQLKGKKELALTLSVLNRVQEHLNASKPVRMLEFTPEEREVLQLYPLLTMKKVIYATNVSENDLPDMENPYVKRVRDYAAAEGNVVISICARIEEEIAQLNLSERQQFLDSLGLQESGLQRLIRASYEMLGLISYITTGEIETRAWTINRGTSAAEAAGKIHSDIQKGFIRAEVVSYEDMVTYKGRVAAREAGKARSEGREYVVKDGDVILFMHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFY9</accession>
    <name>A0A0C1HFY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384675.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76304">
        <property type="protein sequence ID" value="KIC76304"/>
        <property type="gene ID" value="DB41_GK00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="482" mass="55147" checksum="610AF172A7526492" modified="2015-04-01" version="1">MQASTSYHFSPVVPISFLEKINIYYQAEEAFKNSFNPINRGLNLEIIKKLFEEIVQDLSYPPEVILQSKLNLILMDMLRNELSDLALVDEIIDQLCPEQAILLIFCLAESLYSAKSEDDSRATSLLKLYYKLQSYPQCPPYLASVAAFHAGKIWAVGDNNKIEKNLLRANECYDKAIKYLSTDLEVYQVNDRTPLELYYSSLPTYEINHLLSRIYIDKAYLYSKESKNWSACLLNAAIIYNEIIENSLDRTSVEMARLSLKKMYEQQVVAPRLLIHTQTELANLIKIIRTYQETIRNSSSFLMDSPQPWLESFGTIPQFLTFLLEPLDKKTLGYANSIIINLVDAGYNLHEQIETNLSQEKKNKIASILGIACLTSAREDAAEKPELVYRRLQHISPKADCYFDALHDLIVKKYYEVAKQTSSKLAAYESIREHILDAIENLNDATLSPLSPQLLLINTALKLAQKWEIEAEAEKLLLDAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGE3</accession>
    <name>A0A0C1HGE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_GD00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76429">
        <property type="protein sequence ID" value="KIC76429"/>
        <property type="gene ID" value="DB41_GD00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="153" mass="16748" checksum="D41FE04507C1536F" modified="2015-04-01" version="1">MKNLIIRNFYLKFNKAAATLQSVFLLLVRIYFGWSFFWAGLGKLQNIYGTAEAFASLGILYPLFNAYAASLIELVGGACLFLGLGARLAAFALSIVMLVALYTAHYDALLNIYSAPEQLLTQLAFIYLVASMIILIFGPGKASGDSLIEKNCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGG2</accession>
    <name>A0A0C1HGG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243872.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76449">
        <property type="protein sequence ID" value="KIC76449"/>
        <property type="gene ID" value="DB41_GC00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005325">
        <property type="entry name" value="DUF308_memb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03729">
        <property type="entry name" value="DUF308"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="175" mass="18703" checksum="2D086394B96F20F9" modified="2015-04-01" version="1">MNILQKYRIAFIVESILLIILGGIAITAPFIATLSIELMIGSIILLGGGAQLYKSFKAMHEPGGALSLACALISMLVGACMLIYPMAGMQTLTLLTALFFLVEGIIKISISLEIKGTPNWGWLLSSGIIALLMSGIILSGWPETSRWIIGPLVGINMAWFGFSLLALAIHIPTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGS3</accession>
    <name>A0A0C1HGS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FT00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000080">
        <property type="protein sequence ID" value="KIC76534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76534">
        <property type="protein sequence ID" value="KIC76534"/>
        <property type="gene ID" value="DB41_FT00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="7140" checksum="3848D5E8A1DBDBE1" modified="2015-04-01" version="1" fragment="single">RYTLQEARRLVIYAHTSIKQCWSYWLEWSNWRRKHQASACYYHYQRQRKLCLHLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGY7</accession>
    <name>A0A0C1HGY7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tilS</name>
        <name evidence="8" type="ORF">DB41_FM00070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243848.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76574">
        <property type="protein sequence ID" value="KIC76574"/>
        <property type="gene ID" value="DB41_FM00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.723"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="21"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="26"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="441" mass="51260" checksum="AE0E7CE8379D8D71" modified="2015-04-01" version="1">MNLEETLFNFLNIHANHQQPVLLGLSGGSDSLALFYLLIKYRNLKALNFAAAHVDHGWRAESKEEARQLQHLAASMQVPIYLKNLNITQLFGNMEEACRHERLAFFKKLCHQHGYQAVILGHHLNDQAETVLKKVLEGGSLPYLGGMTPVTDYQTLKLWRPFLTCSKSQIKQWLACKNYKFFEDKTNEDERFLRARFRHTIIPHLASTFGKKIEESLCRLGYEAQELKKYLDNHLQGYLKDIIKGPFGSSLNFQLHGMCTDFEMRYLIRKVCESEGLKLSHHLIEQACKKIHSKAANCQFLAKDTWVYIDRERLFVMSKPLLDFREELSFDRVGKYSAGDWTIEVTESLDSPIPITGWQEAWRGRLSIQIPSGKYSFKRGNSSLDKWWTNAKIPAFMRYAFPTLWADDKIIYEFLATRRLVDVHLKSFKCWTVTLCYQPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH96</accession>
    <name>A0A0C1HH96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vitamin B12 import system permease protein BtuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">btuC</name>
        <name evidence="8" type="ORF">DB41_FB00160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243825.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76674">
        <property type="protein sequence ID" value="KIC76674"/>
        <property type="gene ID" value="DB41_FB00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.628"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="357" mass="39225" checksum="DF04A59D3980E12E" modified="2015-04-01" version="1">MNKHLLYIILYFILLLSVILTLTIGETEFIQVWKDALAQLAGSSFYWNPLLDERLPRLIVLLCTGASLAVAGTVTQALFQNPLASPGVLGIPAGGSLLVVIIFICELHYNYPYAIPIAAFIGCLGTLLVVYSLSRRKGYVELTHMVLTGIAVSTLIVTIQSSIIYAFRDRWHIIQTLTEWEAGSTSDRSWMHVHLQLPLTLFGLSSCWLYSKEINMMAFGEEEAKNLGVEVDKIRWRLFLSISLLISGAVAAVGNIAFFGLLLPHLIRRFAGPNNQQLIPLAILGGAAILTAMDVGLRFFSLQAFSIGNISGIMGGIFFLCILMGSRYRHALLGKGDYACMLLLAFILAANLQEINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHT3</accession>
    <name>A0A0C1HHT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="8">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">hisS</name>
        <name evidence="11" type="ORF">DB41_EC00220</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76874">
        <property type="protein sequence ID" value="KIC76874"/>
        <property type="gene ID" value="DB41_EC00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.449"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="58"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="514" mass="58958" checksum="D230959C3CCCA4A6" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHU8</accession>
    <name>A0A0C1HHU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DW00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383689.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76899">
        <property type="protein sequence ID" value="KIC76899"/>
        <property type="gene ID" value="DB41_DW00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="305" mass="33377" checksum="6A2CD4EB567AD398" modified="2015-04-01" version="1">MSQDFTNLNTGMGNQSGLPNAEALYPSKQTSALDSKVQETSLHSKDSIEKASAVVASLYLPPLSNPLLIPPDANNIIAISQLAMDKICLNILDSWSQSLKKIAEEKREAERRKELNPLWQDLNMAGGLVLAVATIFIRAIFGTQIAQALQKNPGLTDEKVIAHKFATQIAQWSLDGVLGGYLMTIVDKLPSAAPMNEGEKKVLAQQMQVMLLAAALGGIYKAKYEWITSKEFMDVLSDPFSLKDSNMAMLAMLLVNTLNELPEASKLRMMKTLNIYMDSNPDLPSLFDLGHTAGVQLSILKATRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIU2</accession>
    <name>A0A0C1HIU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Na(+)-translocating NADH-quinone reductase subunit E</fullName>
            <shortName evidence="12">Na(+)-NQR subunit E</shortName>
            <shortName evidence="12">Na(+)-translocating NQR subunit E</shortName>
            <ecNumber evidence="12">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">NQR complex subunit E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NQR-1 subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">nqrE</name>
        <name evidence="13" type="ORF">DB41_CT00010</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="12"/>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77184">
        <property type="protein sequence ID" value="KIC77184"/>
        <property type="gene ID" value="DB41_CT00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.115"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00429">
        <property type="entry name" value="NqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010967">
        <property type="entry name" value="NqrE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30335:SF1">
        <property type="entry name" value="PTHR30335:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01940">
        <property type="entry name" value="nqrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0915">Sodium</keyword>
    <keyword evidence="11 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <keyword evidence="9 12" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="245" mass="26741" checksum="718BE113BD9FEBE2" modified="2015-04-01" version="1">MWMGNYEPLNLLGLLLQAVFIENFLLANFLGMCTYLACSTKLKTANGLGLAVVFVLTVSGILNWFVHRFVTGAGALDWLSVFGLEASQINLNFLEFLLFISVIAGFVQILEIIIEKVAPALYMSLGLYLPLIAVNCAILGACLFAVTRDYPFWPNLVYVFGSGLGWWLAIALIAAIREKLATSKVIPALKGMGITFMMSGLMAMAFQGFTGIKLAIPTGKPSNADTQMMPFSQVEKIYSETPLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIX9</accession>
    <name>A0A0C1HIX9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="13">ACCase subunit beta</shortName>
            <shortName evidence="13">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="13">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">accD</name>
        <name evidence="15" type="ORF">DB41_CP00090</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="13"/>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77224">
        <property type="protein sequence ID" value="KIC77224"/>
        <property type="gene ID" value="DB41_CP00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.84"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041010">
        <property type="entry name" value="Znf-ACC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17848">
        <property type="entry name" value="zf-ACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="15" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="14">
        <location>
            <begin position="23"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC77224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="308" mass="34254" checksum="FAD001CD0960746C" modified="2015-04-01" version="1">MGLFSRNKPKIKIQTTKKDGYSGWLKCTHCHELIHANELQQNMNCCPKCEYHYRLTTEERIKNLSDENSFQEMYKDLEPVDALNFVDTETYPKRLASAREKSGHNEAAIVGTCRINGNPVALGILDFNFMAGSMGSVVGEKLTLLMEYALASRMPLLIVSTSGGARMQESILSLMQMAKTSAALAKLHEAKIPYISVLTNPTTGGVTASFASLGDIIMAEPNALICFAGPRVIEQVIGQQLPPGAQKSEFLLQHGMIDCIVNRQELKHKISEVLYFLTNNEENNPKDEHPLLAYLPLNNLTKADKPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ24</accession>
    <name>A0A0C1HJ24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Coproporphyrinogen III oxidase</fullName>
            <ecNumber evidence="6">1.3.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ppoX</name>
        <name evidence="8" type="ORF">DB41_CO00380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:43436"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="1.3.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.15" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77269">
        <property type="protein sequence ID" value="KIC77269"/>
        <property type="gene ID" value="DB41_CO00380"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="7">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC77269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="268" mass="29753" checksum="E54EA634354439B4" modified="2015-04-01" version="1">MALLQKELFYIFFKNRAPLPSPYIKKMCQESLFSFREGMQTLSNALVQNLHESILCEQEVTDLNFQEKGIELGLAQGKTLWADQVYSTLPPASLAALIRPHHLPLANLLSSIANASIAVVGLGYKQKLLTPKGFGYLIPSKEKEEMLGMVWDSCVFPQQSLHPSETRLTVMLGGTRMSDFSQKKESDFLNSALKAISNHLQIHAAPDVVDIHLAQNAIPQYLVGHEQKKVLIGKYLQELSPHLQLLGSAFNGVSVNDCIAHAYSMAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ49</accession>
    <name>A0A0C1HJ49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CJ00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77294">
        <property type="protein sequence ID" value="KIC77294"/>
        <property type="gene ID" value="DB41_CJ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7755" checksum="DF8A5BCD86FBF7E7" modified="2015-04-01" version="1">MPSFLCMCLVARFSPKSHYLCINDKLLSFSLLKIDKIRFTPQGSSLKSYPSTQLFSYPKNYIAGSSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ66</accession>
    <name>A0A0C1HJ66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IJ00340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243992.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74563">
        <property type="protein sequence ID" value="KIC74563"/>
        <property type="gene ID" value="DB41_IJ00340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1616"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="9"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="484" mass="55453" checksum="D736701640FAF158" modified="2015-04-01" version="1">MNPSSFISIEHLPNEILVPILKACASPSLSRVCTRWRHLLDTEIMPSLYKQIGQIHALQLDVTERAFIIDKIYKLEANLPEAIKITTIFRHLFILAKSFSPLELEDKPMETRYLTVDNYFSYLININRLLFWKNLPGGQHYLNQEEIEALPLASRGEIFKEWIEKYNKDIKCLGLISIGLTFLSKEIGQLSQLTRLHLINNQLTILPAEIGHLSQLKYFMLNDNYLTTLPAEIGQLSQLRWLELTDNHLTTLPAEIGQLSQLVRLHLDKNQLTALPPEIGQLSQLVRLHLDKNQLTALPSEIGQLSQLVRLHLDKNQLTTLPAEIGHLSQLGWLKLTDNHLTTLPAEIGQLSQLETLDLNDNQLTIFPLEITELFQLKNLELSNNLLAGLPPEIGHLFHLELLSLDDNHLTDLPPEIGHLFHLRALYLNDNQLTSLPAELGRLSSLRRLYVRFNQLTSLPSEIKPSYERLYIELEGNPLEYNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK43</accession>
    <name>A0A0C1HK43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74873">
        <property type="protein sequence ID" value="KIC74873"/>
        <property type="gene ID" value="DB41_IB00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6820" checksum="FB092BD470AB6060" modified="2015-04-01" version="1">MIHLKKSLKINLRVSRKNHLCIAEGFKKLGIIYYSLENFKQKDKCFELARRNELKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLT1</accession>
    <name>A0A0C1HLT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HO00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75358">
        <property type="protein sequence ID" value="KIC75358"/>
        <property type="gene ID" value="DB41_HO00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6014" checksum="188E6FCEDF4FE1DF" modified="2015-04-01" version="1">MLVLATDGTTEVLGSQEIIPLLQNEEEPVDKLVKEAIKRKSEDNNPVIVIKLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN64</accession>
    <name>A0A0C1HN64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="1">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yfhC</name>
        <name evidence="1" type="synonym">tadA</name>
        <name evidence="3" type="ORF">DB41_HF00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385122.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000116.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75773">
        <property type="protein sequence ID" value="KIC75773"/>
        <property type="gene ID" value="DB41_HF00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1158"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="167" mass="18918" checksum="15B1A792C1A1BE6F" modified="2015-04-01" version="1">MLFPFTFKPQSEDEKFMLEALKEAWKAFRQGEVPVGAVLVHEGQVISRGYNQVELLKDATAHAEMLCITAGEVAMENWRLTGTTLYTTIEPCCMCAGAMFLSRISTLVWGAPDLRHGANGSWMDVFEKVHPTHNLNIKRGVLEEYGAALMRDFFKKCRREKKSLTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNN5</accession>
    <name>A0A0C1HNN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GX00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000109">
        <property type="protein sequence ID" value="KIC75908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243915.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000109.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75908">
        <property type="protein sequence ID" value="KIC75908"/>
        <property type="gene ID" value="DB41_GX00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="12"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="126" mass="14075" checksum="EC00E42CC0B5F162" modified="2015-04-01" version="1">MGAIAGRSFARESFIAAKCKSKILAPFCYTGTCNSLLFNFWLEKILIPELETGQVLIMDNATFHKSQATHELIKKAGCEILFLPPYSPDLNPIETFWANFKKIVAANLSKFSTLAQTIDYSFLSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ31</accession>
    <name>A0A0C1HQ31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76308">
        <property type="protein sequence ID" value="KIC76308"/>
        <property type="gene ID" value="DB41_GK00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7278" checksum="9A1BFBE782898685" modified="2015-04-01" version="1">MGYLADTISVSCNSSNIFPGASVLHLRIFVKTSYQNNTFLYMFLRYFTPSSIYLHPLVILQHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQI0</accession>
    <name>A0A0C1HQI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 15">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="15">Kdo transferase</shortName>
            <ecNumber evidence="7 15">2.4.99.12</ecNumber>
            <ecNumber evidence="8 15">2.4.99.13</ecNumber>
            <ecNumber evidence="9 15">2.4.99.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15 17" type="primary">waaA</name>
        <name evidence="17" type="ORF">DB41_GC00100</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 15">
            <text>alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2-&gt;8)-alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28154"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:60365"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="ChEBI" id="CHEBI:86234"/>
            <dbReference type="EC" id="2.4.99.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>alpha-Kdo-(2-&gt;6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28062"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60365"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Single-pass membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="7 15"/>
    <dbReference type="EC" id="2.4.99.13" evidence="8 15"/>
    <dbReference type="EC" id="2.4.99.14" evidence="9 15"/>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76443">
        <property type="protein sequence ID" value="KIC76443"/>
        <property type="gene ID" value="DB41_GC00100"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="15" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="11 15 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Glycos_transf_N" evidence="16">
        <location>
            <begin position="35"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="14">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="14">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00012625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KIC76443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="430" mass="49589" checksum="60ABAB4D12174070" modified="2015-04-01" version="1">MILSFLYDSMLCLLALLSLPKVSYDYFIKKKYQQSLARRLGFNFPLITKGERRLVWIHAVSVGEAKAATSLVKTLRTQLHDPVIVISSVTEAGHAEAKRSIPQADYHIYLPVDLAFIIRPIMKRAAPDLVILVETDFWYNFLKAAKDLGSLIVVVNGKISERSFQRFLKIPYFTHKLFSFIDLFCLQSKHYYERFKALGVDPHKMQITGNLKFDDEYPRFTAEQHAAWKKRFQIEEINQIVVLGSSHDPEEKMILEQMKIVWEELPHVKLIIVPRHPERFNEVARLLEKEFISYVRFSQIDQPVNNAKVILIDAMGLLRKCYQLADLAIVAGSYTARVGGHNILEPSWYGVPVLYGPYMHSQPELVELMEDYKAGRQVDINHLSHEMIVLLKDSQLRQSIGANGVRMFKDIKGATQKTWNFIEPLIKKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQI6</accession>
    <name>A0A0C1HQI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Formamidopyrimidine-DNA glycosylase</fullName>
            <ecNumber evidence="19">3.2.2.23</ecNumber>
            <ecNumber evidence="19">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">mutM</name>
        <name evidence="19" type="ORF">DB41_GC00150</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="19"/>
    <dbReference type="EC" id="4.2.99.18" evidence="19"/>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384519.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76448">
        <property type="protein sequence ID" value="KIC76448"/>
        <property type="gene ID" value="DB41_GC00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.844"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 19" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 19" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="240"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KIC76448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="284" mass="32070" checksum="7EA142E4CEF0E65C" modified="2015-04-01" version="1">MPELPEVETIVRELIATGLVGKQIATAYVQWPKIIDTSDDQVFIHQIQGQSINNLARRGKYLVFTLSQSTLFVHLRMSGKFEWLANPLPIKKHEHVRLVFTDGTILRYEDPRKFGRWSLYSDPLEKLSRLGLEPLSSNFTCSALTSMLQRYASQIKPFLLNQKHIVGLGNIYVDEALWEAKINPQQLTNSLTKKEIKALHQAIQNVLNKGIENKGTSLGVGASNYYSVSGRRGGHQHHLKVFRQQGLACSRCSTLIIKIVVAQRGTHLCPTCQKSVIFNEIKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQN3</accession>
    <name>A0A0C1HQN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GA00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384447.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76488">
        <property type="protein sequence ID" value="KIC76488"/>
        <property type="gene ID" value="DB41_GA00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="148" mass="16166" checksum="93D046DD91C623CD" modified="2015-04-01" version="1">MRNTPGIVLGALVGAGLASACALLPFRQQGKKKLNHPKKEGNIKGKPYTKETFLNKVFPFTAVAIPSTVKTFAEGTVIGLVLGIGCAVLLTPQSGRQLRKELRNKYQRMLTKKPDLIPPSDLTPAPSKRAKRVNQVVENKKKKRSPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQR5</accession>
    <name>A0A0C1HQR5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protease HtpX homolog</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">htpX</name>
        <name evidence="14" type="ORF">DB41_FU00030</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M48B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384331.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="M48.002"/>
    <dbReference type="EnsemblBacteria" id="KIC76518">
        <property type="protein sequence ID" value="KIC76518"/>
        <property type="gene ID" value="DB41_FU00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.761"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00188">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022919">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="13">
        <location>
            <begin position="84"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="303" mass="33801" checksum="18B33120416553A3" modified="2015-04-01" version="1">MAFAKRIILFLVVNFLVVAFISFITYFFNLQPFLMKKGINLPSLAIFCLLWGMGGAVISLLLSKVMAKWMVGLEMIDPHTTDLQKRAVLETVYQLAKKAGLPKMPEVGIYYSPELNAFATGPSRSNSLVAVSSGLIERMEKNEVDAVIGHEITHIANGDMVTMTLLQGVINAFVMFLARIVAYGISKTFSKERDEEPSPFMYQMIVFGLEIVFMILGSLVVASFSRYREYRADAGSARLVGASSMIAALQALKSNFEVKDPNQNQEAINAFKISGTKKGLMQWFASHPPLDDRIARLQQLYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR11</accession>
    <name>A0A0C1HR11_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">alr</name>
        <name evidence="7" type="ORF">DB41_FK00050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384247.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000072.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76583">
        <property type="protein sequence ID" value="KIC76583"/>
        <property type="gene ID" value="DB41_FK00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.709"/>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="703"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="724"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="773"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="841" mass="93953" checksum="B91E91346F10F1E0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRD2</accession>
    <name>A0A0C1HRD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FB00250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243827.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76683">
        <property type="protein sequence ID" value="KIC76683"/>
        <property type="gene ID" value="DB41_FB00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.636"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="211" mass="23418" checksum="2F0351775C3A6ECE" modified="2015-04-01" version="1">MSQLQWLSLTSNQLTALPAEIGQLSQLKGFNLRGNQLTALPAEIGQLPQLKGLDLSQNQLTAISAETGQLSQLTKLDLSHNQLASLPAEIGQLSQLEYLHLEGNQLATLPAEIGQLSQLKELYLSNNRLTVIPEEIGRLLQLHFLDLNNNRLTVIPEEIGQLLQLYSLALNNNQLTSLPAEIGQLSQLRALQVKENPLKNIPDKIKQRFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRF5</accession>
    <name>A0A0C1HRF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383992.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76708">
        <property type="protein sequence ID" value="KIC76708"/>
        <property type="gene ID" value="DB41_EY00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="263" mass="28726" checksum="445B71362C5B4AAC" modified="2015-04-01" version="1">MKQDFKNQTVMITGASSGFGAAFAEAFAREGASLINIARRKDRLQALESSLQEKYGVEILSIELDVSDEKAVVEKLGLLAKDSIVPDLLINNAGMVRGLNKVWETPTQDWNEMIDINVKGLLNVSAQIIPHMVKKNAGHIINVGSISSHDTYPGGGIYCATKFAVKAITDTLRKELVNTPLRVSMISPGMAETEFSLVRFAGDKDKAHAVYENIQSLTAEDVAEIVLFMATRPPHVNLADVVVYPTHQASVSLIYRGERKAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRU6</accession>
    <name>A0A0C1HRU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EG00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243800.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000046.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76843">
        <property type="protein sequence ID" value="KIC76843"/>
        <property type="gene ID" value="DB41_EG00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002151245" evidence="1">
        <location>
            <begin position="28"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="360" mass="41047" checksum="D46357EE583A1CBE" modified="2015-04-01" version="1">MKKQKILFFSALIYGCLAALLQAEGNAAFLGKEDSSALVVNNRILAKVNGTAISVLDVMKKMDVLFYREFPDYTSSTQARYQFYKVNWKHVLDELVNKELVLADASENKLLVSNGDIRQEMESLFGPHIINNLDKIGLSYEEAQKIVQGDIIIRRMIYLRVNAKALKKVTPQAVRLAYEEFANDPANLKPNTWQYNVISIRDPDAARSAEAAHLTYQALNEHIALEKLSTYVKANSHFDNTQINVSEEYTLPEKDISEAYKAILTKLTPHSHSQPIAQKNRADKNSSFYRIFVLKNWIKGGTPTFKEVELKIKDRLIEEAIAQETEAYLKKIRKRFSVQDFYTPKTDQAAFEPFILGSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS35</accession>
    <name>A0A0C1HS35_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin--[biotin carboxyl-carrier protein] ligase</fullName>
            <ecNumber evidence="2">6.3.4.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">birA</name>
        <name evidence="4" type="ORF">DB41_DT00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.15" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383642.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76908">
        <property type="protein sequence ID" value="KIC76908"/>
        <property type="gene ID" value="DB41_DT00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="240" mass="27397" checksum="8DB43B6F6A1B5356" modified="2015-04-01" version="1">MKINCLYFNTLDSTNSWSKKNYKNFDPTCITLVFADHQTMGRGQYQRRWLSPAGQNIYATFTFFVDSRQTFVANIPQVLALAALKTLKELRLQPCLKWPNDILINKKKIAGILCETITDNYQSVIVTGIGMNVNMPLEITSQIGQPATSLFIETEQTFKTSQILDLLKNNFMPLLHLFLEKGFQPLLEDFKQGILHQPGDVIRINKHEGTFEEIDKQGALVLRLPNGRIQKFYAGELLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSR2</accession>
    <name>A0A0C1HSR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DD00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000020">
        <property type="protein sequence ID" value="KIC77083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77083">
        <property type="protein sequence ID" value="KIC77083"/>
        <property type="gene ID" value="DB41_DD00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="403" mass="45165" checksum="C8CE8DC948BBB4FE" modified="2015-04-01" version="1" fragment="single">AVPSLFSVCKRWHHLLASEAMPSLYKKIAQLHFPTKNASTPRTLMLAKVYQLNPGLTSTEKVYQVFKQVFTLAKSISPLEFKWKTEEKRGLTLANYSSYLLNINRLLLWRKLPGGEEYLKREEIKHLPLEKKGELFRDWIEENCKSITALKLSGAGLTYLPPEIGQLSQLQRLYLNQNQLTSLPGEIGQLSQLTQLFLNQNQLTSLPAEIGQLSQLQYLYLDQNQLTSLPAEIGQLSKLQTLDLNQNQLTALPIEIGQLSQLRALELNQNQLTSLPTEIGRLSQLEVLKLKQNQLTSLPAGIGQLSQLQLLELNQNQLTSLPAGIGQLSQLQELYLSQNQLTTLPVGIGQLSQLKGLDLSQNQLFSLPAEVGQLSELQGLYLNQNQLTSLPAEIGQLSELQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JIR0</accession>
    <name>A0A0C1JIR0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BR00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000238">
        <property type="protein sequence ID" value="KIC71275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71275">
        <property type="protein sequence ID" value="KIC71275"/>
        <property type="gene ID" value="DB41_BR00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="453" mass="51757" checksum="6199F4DDF46E2438" modified="2015-04-01" version="1" fragment="single">QISLKIFQELSQQDLTNARGVCKEWKQLIEQNNGWKRLHLKKIKSNLPTTNQLANKANSLDPFPPHWSPFQIAKSLWCNPATIISGSQKAKVNAVAAYLHKEGFELKGVASDGDCFFSAFLGSYKELSRKIPLLDEHPDKTSYLRQVLSDIIKHTNSKRAEEIIEKGSWISGLGEGDLLASALSIPIRLVTINEERLICGVNDMLIFSKVGLTSKKVRSREWETIPQEERPQEYILIVDLGGHFIYAQKPLKQDKTLLSKSNPPTNFLFSNSLSTNELKNTLKTLESEELLSGEKIKELEQTYTLALQIAVQWKDPIQESFCIEELGDIYLRKQTSETLLQAAGLYNYALRLAPPQRQKILRDRLSQVQNLLVKQCKGTPFDSVVIEKQFERNRSELKKFREEIEKKIQTLPENPSSQEVRELYGEIAHHIKIFFGQLVIQAVHQLDTEPCEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK93</accession>
    <name>A0A0C1JK93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AQ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71710">
        <property type="protein sequence ID" value="KIC71710"/>
        <property type="gene ID" value="DB41_AQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="13811" checksum="4DE8B1D8816504CD" modified="2015-04-01" version="1">MLIQPLCKKIKFLLRKNAEKVTTTQGNKMHPISSASIESLPNELLLPILEACVVPSLFSVYKRWHHLLASEAMPPLYKQIGKVHVPQGNAKEQALIVDRIYKLEEKLSEAAKVNAIFRQILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK98</accession>
    <name>A0A0C1JK98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AQ00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71715">
        <property type="protein sequence ID" value="KIC71715"/>
        <property type="gene ID" value="DB41_AQ00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="318" mass="35539" checksum="F024F3C20961B81C" modified="2015-04-01" version="1">MAVKIVTNLFLGSIGLCLVACSCKEAGQLEPNIQFAAPVHVIENLPSAFPDLTSEELQEDWAKELLIANKFARENDLYRAITSYKRALILIPSSQLYRKQQIEYDIILSYYLGEKYQEAVEAFEASSLTNISAQFLAFENLLQILYDAYSRAGQPAKAEKVFALLQKVRPKVAENLQHAEDVIHANFSALHSPCLGSNENLSYFLTTYNQHAKSVRHAKTLNALLPGAGYYYLGQKNTAITAFLVNSLFIATAYYFFDHGNWAAGAITTSLEMGWYIGGINGAGLGAKEFNEHLYKTLAKDYMIKNHLFPVLTFQTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKF7</accession>
    <name>A0A0C1JKF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase for insertion sequence element IS5376</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">istA</name>
        <name evidence="2" type="ORF">DB41_CI00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000254">
        <property type="protein sequence ID" value="KIC71071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039387100.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000254.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71071">
        <property type="protein sequence ID" value="KIC71071"/>
        <property type="gene ID" value="DB41_CI00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2323"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="20"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="324" mass="38092" checksum="7389829387575767" modified="2015-04-01" version="1" fragment="single">ERAVKPFRDELQVKAQATLRFETPPGKQLQIDFGSTRLYIQDKLTQVFLFVATLGFSRRIYVKPFLHQQQSSWFKGIEEAFFYFGGTTEEVLVDNAKSLIIKHHALTREVQFNERFTAFANYWKFCPKACAPYRARTKGKDERAIGYVKRNAIAGHKFASWESFESHLEHWMHNISDQRLHGTTRKVPLKVFEEMEKDALRPLKGKPPFLQIRELDRIVHKDACVEIDTNRYSVPWKIIKERVFVQLIENEVRIFYKQTEIARHVECKGKYQNILKPEHLKGIVGTFRPKEHEEIKCVENLNFMDAELSRPLAEYERLVGGSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKV1</accession>
    <name>A0A0C1JKV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BZ00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000245">
        <property type="protein sequence ID" value="KIC71191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71191">
        <property type="protein sequence ID" value="KIC71191"/>
        <property type="gene ID" value="DB41_BZ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6184" checksum="70B41CD4F9DF2764" modified="2015-04-01" version="1" fragment="single">MEAKQTMLSSSSSSSAPEQEPEELQDPITLTLLVTTPPHNRHFVFVRRDFKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNS5</accession>
    <name>A0A0C1JNS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KR00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386523.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72191">
        <property type="protein sequence ID" value="KIC72191"/>
        <property type="gene ID" value="DB41_KR00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133935" evidence="1">
        <location>
            <begin position="20"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="427" mass="49395" checksum="63FCC83E18E26FCA" modified="2015-04-01" version="1">MKQLKLLPLLIFLVCIAHGCIPTSLRDEQPALISINLIDRNGLNETITNKERLNQYENVNFLGAQPYQKVLRVYQKDSQGSSPAYITTYYENGQPRQYLEAVNNRAYGFYREWYKDGTLKLEVTLIGGIADLTSSAEKSWQFEGRARAWDENGNIQTEITYEKGLLEGDSIYYHPNGRIWKRIPFHKNQANGIAEYYLDNGQLLQTIIFCNGARHGEAIRYWPPKKIAAQEYFDQGLLVTGQYFDREGSLIAEIIEGEGYRAIFNKKNVQELQQFQGGVLQGKVKIFDESNRLQRLYHIENGLKNGEEYEYFLLKGLKEARPKLLINWYQGKINGYVKTWYENGTVESQREIVNNKRNGLATAWYQDGSLMLIEEYDRDLIMKGGYYKRGDKNPISEILNGQGVATLYDGDGRFIRKIHYYNGKPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQD2</accession>
    <name>A0A0C1JQD2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KD00260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72726">
        <property type="protein sequence ID" value="KIC72726"/>
        <property type="gene ID" value="DB41_KD00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="53"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="16712" checksum="D64A58D77AD6B6D3" modified="2015-04-01" version="1" fragment="single">MRSNKLADALLVIRIRIRLTCFFNFFILPLKIKMIKVITTPENKMHPLSSASIESLPNELLLPILEACAVSSLFSVCKRWHHLLASEVMPSLYKQIAQLHFPRGNATTQQTLMLAKVYQLNPILTSTEKAYQVFKQVFTLAKSISPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JR77</accession>
    <name>A0A0C1JR77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative dual-specificity RNA methyltransferase RlmN 1</fullName>
            <ecNumber evidence="13">2.1.1.-</ecNumber>
            <ecNumber evidence="13">2.1.1.192</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">rlmN1</name>
        <name evidence="13" type="ORF">DB41_JV00070</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="13"/>
    <dbReference type="EC" id="2.1.1.192" evidence="13"/>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386244.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000178.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73016">
        <property type="protein sequence ID" value="KIC73016"/>
        <property type="gene ID" value="DB41_JV00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1831"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="100"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC73016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="355" mass="40053" checksum="4BDBC577BF4E4A92" modified="2015-04-01" version="1">MNSTVNLLSYTHHSFCNFIAAELGKGYLHAGLIYEEFYRTGTVFGHHPAFHNASRLLREILLRVDLSLPLVPVEKDDGETKKFLLKTQDNLEVEAVLIPMQAGGTLCISSQVGCRRGCTFCETGRMGLLRNLKVEEIIGQVFVVRHVLRYPIRNIVFMGMGEPFDNYENVRQATHILMDPKGLGFGRNHLTISTSGVIEGIHKFTHSAGPKPHLAVSINAPTDEIRQRLMPINRKHDMQQLYKAMREYNEVTGLKILTAYVLIKDVNDSLEHAERLADYLKGLHVKINLIPYNPQTGDRFARPAEETVTAFRQHLRLQGYQTLLRATKGKDIMAACGQLGNIKLRAQLKKNLEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRK9</accession>
    <name>A0A0C1JRK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protease 3</fullName>
            <ecNumber evidence="3">3.4.24.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pitrilysin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Protease III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protease pi</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ide</name>
        <name evidence="17" type="ORF">DB41_IY00110</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.55" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73815">
        <property type="protein sequence ID" value="KIC73815"/>
        <property type="gene ID" value="DB41_IY00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="14">
        <location>
            <begin position="80"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="15">
        <location>
            <begin position="236"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_M" evidence="16">
        <location>
            <begin position="420"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="15">
        <location>
            <begin position="714"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KIC73815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1003" mass="115095" checksum="9DA32B8A941D4077" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JS01</accession>
    <name>A0A0C1JS01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JM00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386163.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73251">
        <property type="protein sequence ID" value="KIC73251"/>
        <property type="gene ID" value="DB41_JM00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="14594" checksum="5DFFF3EC4795C88F" modified="2015-04-01" version="1">MVNILANADNHKDGTAISPNDSTVTSIKQLPDELLVHIFSFLQALDLLEVELTCHRWKNLAEDKTLWKNLYQKHLKIYWREGKSNKKSYFITLHGEREYEKTMAFLGSLKKVERNFELAKYIGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTV5</accession>
    <name>A0A0C1JTV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385923.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74535">
        <property type="protein sequence ID" value="KIC74535"/>
        <property type="gene ID" value="DB41_IJ00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="236" mass="27302" checksum="F4C256111E423CFF" modified="2015-04-01" version="1">MLNVKSSPVPYQASKWLSLAMLIDEDEIQTLFQALGDFKIFSIGKVEKSGEGQISHEVFLANYTQYIQSLKSRRTYEMEYFRTFFTSVLTSSADHLYAWSIGNDRQLIRIAKPVVQLQLHTLDYSVADNKFRSMVLGKDPVSWGLQFSYPQLYQDPQTHAVYKVGEAYANTALFRLIQQWQRKYTVPTPFLIKDKLINVSMRLGKKCFSWINQHPQLENRGLQVQIPHPTNSSIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVG5</accession>
    <name>A0A0C1JVG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74401">
        <property type="protein sequence ID" value="KIC74401"/>
        <property type="gene ID" value="DB41_IP00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5108" checksum="E9203E583BAD6F85" modified="2015-04-01" version="1" fragment="single">YLYAGCHLGSKQVAPKFILEELLTPSFDIIFTLSTLGPIVHFRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVQ3</accession>
    <name>A0A0C1JVQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein ORF8 in nfe locus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HV00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243949.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75130">
        <property type="protein sequence ID" value="KIC75130"/>
        <property type="gene ID" value="DB41_HV00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="1">
        <location>
            <begin position="53"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="151" mass="17504" checksum="3B8CAC2273191475" modified="2015-04-01" version="1">MKPIKLDNQQGRLFKSRFSDELNPNHPLIQLSKLIEWKQLEEEFDKLFVEKIGQPAKPVKLVVGLFILQHMYGLSDKNVVHRWVENPYWQYFCGYEFWHHALPIHPTSLIKWRHRLGEDGLSKILQGTIAAAVLTGAVKKKALKKSSPIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVZ2</accession>
    <name>A0A0C1JVZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein in ycf23-apcF intergenic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_IJ00320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385946.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74561">
        <property type="protein sequence ID" value="KIC74561"/>
        <property type="gene ID" value="DB41_IJ00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1613"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="242" mass="26940" checksum="3111CD5427B0268A" modified="2015-04-01" version="1">MPPVIHIDHLNFAYAETPVLTDIHLTIESNDFIGIIGPNGGGKTTLLKLLMGFLKPSSGKIEILGSPPQSSRHQIAYVPQTHRYDREFPISVLEVVLAGRLSKLPWYGKFSSADKEAAKEALNRVKLPNFYNKPFGTLSGGQAQRALIARALISDPQLLLLDEPTAHVDSQAEADIYDILYSLRQKMAILMVTHDLNTAIEQVKQVLLVQNTALLLKPEEVCEHFAMGLYHSPLIQLKREIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVZ5</accession>
    <name>A0A0C1JVZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acetate kinase</fullName>
            <ecNumber evidence="3">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">ackA</name>
        <name evidence="5" type="ORF">DB41_IJ00370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74566">
        <property type="protein sequence ID" value="KIC74566"/>
        <property type="gene ID" value="DB41_IJ00370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1618"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="174"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="248"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="296"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="361" mass="40225" checksum="23D878878BA6B471" modified="2015-04-01" version="1">MGGQVLLNLLYLKQKTFFLRHLEPLWQKTVEFENSWEDRRAAIKKAFEEVPTPIDRVGHRIVHGGSLFQKPTFITPETIKLLQKLSHLAPLHNPINLEGIQEAERYFPSATQIGVFDTAFYTSMPEVAWTYPVPSEWTKEGIRRYGFHGISHQYCMETIQERLGSDNHKLITCHLGNGSSCTAILNGKGIDTTMGFTPLEGLMMGTRSGSIDPGIILYLQKQKNMSVEEVDHCLNKKSGLLGIGGSFDMRKILKAAERKDSRAILALELYVHCLKKAVGALAATLNGLDILCFTGGIGENAAPVRQKVIEGLEYLGVKVDSSLNGTWKNDGEISPAGSKVKVFVVHVREEWLIAKECFNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW82</accession>
    <name>A0A0C1JW82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HO00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385380.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000125.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75355">
        <property type="protein sequence ID" value="KIC75355"/>
        <property type="gene ID" value="DB41_HO00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="337" mass="38843" checksum="94B6B28472C114CB" modified="2015-04-01" version="1">MHITIAERLRPFSHTAGTYCVLPGSLLRFQIFPALLRVYDLSYAVPKLIQETPVPVKGPVKEFTVQLDLEKGAIDVWGFDLHAYFRYRILTTQQPKQFALYIDKGLTAWKPEQLILNHEVGSFFSAERLSLGNHKNQDWERVAIRENLTEIFPIWLRLGQLLTSPSKVAYVGTAALFKDCLSASKEDVYDAFINLFKVAFEGILSPRLNDEQYQGFALDAAPPTLSPLILLTEGARIIRSLFIRTQLNEIFVLPSLPAQFHCGRFLHIQCTSLGLLDLEWTKHFMRRMIFHAESDELVQFHFPKNVKRYRLNGQFQLVEKPIQISKGKVYTFDNFQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXJ4</accession>
    <name>A0A0C1JXJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243927.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75800">
        <property type="protein sequence ID" value="KIC75800"/>
        <property type="gene ID" value="DB41_HE00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="82" mass="9438" checksum="43FE73683E7EE9EE" modified="2015-04-01" version="1">MQQLFWQSRRRKSLKKVMATTTGMSKAIAFPTDVKLYFKSIQVLVKMADSCQVTLRQTYKKLAKKAFYIRARLSPCSSAIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY13</accession>
    <name>A0A0C1JY13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lysS</name>
        <name evidence="9" type="ORF">DB41_GW00120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75940">
        <property type="protein sequence ID" value="KIC75940"/>
        <property type="gene ID" value="DB41_GW00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1054"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="207"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="539" mass="61828" checksum="2CF95C2E54F06A0A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYB9</accession>
    <name>A0A0C1JYB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative addiction module killer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HL00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75471">
        <property type="protein sequence ID" value="KIC75471"/>
        <property type="gene ID" value="DB41_HL00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8252" checksum="3B6020CB86A1CC5C" modified="2015-04-01" version="1">METLAIAKPYKKGFASFKIHYGPEIRIYYGKIGNKVILLLCGGDKSSQERDIAKAKEYLKDYQSRELDHGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ63</accession>
    <name>A0A0C1JZ63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein YlbG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ylbG_3</name>
        <name evidence="1" type="ORF">DB41_GK00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76310">
        <property type="protein sequence ID" value="KIC76310"/>
        <property type="gene ID" value="DB41_GK00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="8490" checksum="126E60801928D8BB" modified="2015-04-01" version="1" fragment="single">ERGLFKELYETGGEAALQDLTHKKPCIISRLDEFIEKAVVNFALQRPAYGQLRVCNELEETRSSHFARGCAFCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ84</accession>
    <name>A0A0C1JZ84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75756">
        <property type="protein sequence ID" value="KIC75756"/>
        <property type="gene ID" value="DB41_HG00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1182"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026405">
        <property type="entry name" value="Chlam/Ver/Plancto_rRNA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04137">
        <property type="entry name" value="Chlam_Ver_rRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="5975" checksum="C96D7FA9F181EA29" modified="2015-04-01" version="1">MSRHPSFGKANKGATKRNVLKRFERIDVLKKLGRWDAEKKTRITGLPKTPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZA8</accession>
    <name>A0A0C1JZA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385066.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75786">
        <property type="protein sequence ID" value="KIC75786"/>
        <property type="gene ID" value="DB41_HE00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="323" mass="36407" checksum="EE2FC46524D4FF4F" modified="2015-04-01" version="1">MNYADFIPIISSTLTTFPLLDRIQSIQGIHSSTTITCKVDNACKERFINGQQLCTVEPLNISFTCKREADSIDIRVVEIYNKIFNDTIQEEFTRNQQCNHAQVAGPCGNQRQFLNECRCGPLDRVTKPSLRRQYEDQIIFTILNIKQKLPFQRTFNITIFASGGLHGELVLMVKLINRLKQEGFSGCINLFLIDQIYADNIKFASASTGNFSLNWEAAIGRNQALGQFLTEMALGLPQTIQVTSHVFGDIDDYIWRLEKDSNFDWHCDLLIGADTEDNGTNFAKLQSSASRTNIPGIALAKFHEKPQLCLVTPKGMEVCVPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K004</accession>
    <name>A0A0C1K004_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GP00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384829.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000101.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76036">
        <property type="protein sequence ID" value="KIC76036"/>
        <property type="gene ID" value="DB41_GP00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="57"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="260" mass="29999" checksum="D5103D6B36E53A5F" modified="2015-04-01" version="1">MKTPTKLPHPKAASWEPASQWYKNLVGEEGHYYHQQIIIPNLLRLLNLQACSSPAILDIACGSGVLARHLPTHTNYMGIDLSPTLIKEAKKLDTNLQHHYRVADVTKNLSLDDKKFTHATIILALQNISSPLQVFHNAYKHLEKQGVLIMVLNHPYFRLPRQTSWQIDKDKKLQYRRVDRYMSPLEIPICAHPSKGQQSAQLTSYHFPLCNYFHWLREAGFSVYDMEEWCSNKVSTGANAKMENRSRQEFPLFMTLCAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0D3</accession>
    <name>A0A0C1K0D3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_FH00010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76620">
        <property type="protein sequence ID" value="KIC76620"/>
        <property type="gene ID" value="DB41_FH00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="32"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="5">
        <location>
            <begin position="137"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="952"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="994"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1036"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1088" mass="124269" checksum="487BCB72B89F02C3" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0V1</accession>
    <name>A0A0C1K0V1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease Z</fullName>
            <shortName evidence="8">RNase Z</shortName>
            <ecNumber evidence="8">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">rnz</name>
        <name evidence="10" type="ORF">DB41_EJ00100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383859.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76780">
        <property type="protein sequence ID" value="KIC76780"/>
        <property type="gene ID" value="DB41_EJ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.525"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02651">
        <property type="entry name" value="RNase_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="9">
        <location>
            <begin position="34"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="303" mass="34545" checksum="EC34343FE80777A4" modified="2015-04-01" version="1">MTVRDIIILGCSSQQPTRMRNHGAYLVRWNDEGLLFDPGEGTQRQFIFANVAPTVVTRIFVSHFHGDHCLGLGSVLMRLNLDKVTHPIHCYYPASGKRFFDRLRYGTIYHELIHVVEHPVSKGGLVHDDGKFRIEAVELDHGVENLGWRITEPDTRKYDRNNLQALGVKGPLVRELEQKGFLVLDGKTVTLDQVSHIRKGDSLAVVIDTRYCQNAIDIARHAKVLICESTYLEEHQELARKHFHLTAKQAATIAKEAGVKQLILTHFSARYQNLRPFEEEARAVFPQTYIADDLLTFPFPKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Y4</accession>
    <name>A0A0C1K0Y4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EI00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76810">
        <property type="protein sequence ID" value="KIC76810"/>
        <property type="gene ID" value="DB41_EI00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4909" checksum="98FA35C857B6368E" modified="2015-04-01" version="1">MGVFFKSFVIDKERSFIVFYIGQRLLSWEESISSFISIKWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K103</accession>
    <name>A0A0C1K103_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GC00280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384542.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76461">
        <property type="protein sequence ID" value="KIC76461"/>
        <property type="gene ID" value="DB41_GC00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7302" checksum="9BFF15F19B6E9C87" modified="2015-04-01" version="1">MIICLCLLVYILTQRHLRQQLQRLSTSIVNQLGKPTKMPTLRWIFRVLEAVYLLIKCTLEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K192</accession>
    <name>A0A0C1K192_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_JO00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000171">
        <property type="protein sequence ID" value="KIC73187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73187">
        <property type="protein sequence ID" value="KIC73187"/>
        <property type="gene ID" value="DB41_JO00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="307"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="377" mass="41085" checksum="1704578E6708DBEB" modified="2015-04-01" version="1" fragment="single">NLKLFGENHPKVAICHSNLGQIYKDQGNLGKAAECSSKVLAIDLKLFGENHPMVAIDYSNLGQIYQAQGNLGKAAENSNKALAIDLEIFGENHPMAARDYNNLGQIYQDQGNLDKAAECNNKALIINLKLFGENHPDVAINYSNLGQIYKDQGNLGKAAECSNKALAINLNLFGENHPGVAIDHSNLGQIYKEQGNLEKAEEYSTKALAINLKLFGENHPKVAICHSNLGQIYKGRGNLDKAAEYSNKALTISVKLFGENHSAVATDYSNLGQIYQDQDNLGEAADYSNKALTISVKLFGENHTQVATNYSNLGAIYQAQSKLGKASEYFSKALAINLKLFGENHSTVAIHYSNLGVIYKEQGNLEKAEEYSTKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1F4</accession>
    <name>A0A0C1K1F4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_FN00130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384294.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000075.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76566">
        <property type="protein sequence ID" value="KIC76566"/>
        <property type="gene ID" value="DB41_FN00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="49"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="131" mass="14829" checksum="8AE079DB971CB3BB" modified="2015-04-01" version="1">MSIPEKFDLHSELAKCKTVDDLTGKNGLVQRLIGNMLEQMLQKEMDEHLGYEKHSSKGHLSGNSRNGHAKKTVKSNHGAINLQVPRDRKADFEPIAMKKPQRNISSFDDKIISMYAKGMTTRDIQSHVQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1J2</accession>
    <name>A0A0C1K1J2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76960">
        <property type="protein sequence ID" value="KIC76960"/>
        <property type="gene ID" value="DB41_DP00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7147" checksum="953FBB7CF8C46DA6" modified="2015-04-01" version="1">MVSVENSSFTFNDILEQTEEESFLPALNVIVNKRHTIINNTPPLSAASDLAMTAVEVKGMFTVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Q7</accession>
    <name>A0A0C1K1Q7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="10">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="10">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">gatB</name>
        <name evidence="12" type="ORF">DB41_FI00260</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384185.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76616">
        <property type="protein sequence ID" value="KIC76616"/>
        <property type="gene ID" value="DB41_FI00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.699"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="11">
        <location>
            <begin position="335"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="486" mass="54505" checksum="A46D6087CFB4B2B4" modified="2015-04-01" version="1">MTQHINWEAVIGLEIHAELNTKTKLFSVAPNHFGDEPNTNITEVCTGQPGALPVLNKEAVRKAVQFGCAINSTIAKFSKFDRKSYFYPDSPRNFQITQFEQPIVLGGTVVAEVNGIEKTFAVNRVHLEDDAGMLKHFTNFAGVDYNRAGVPLIEIVSEPCIHSADEAVAYASAIKAILQYIDVSDCNMEEGSLRVDANISVRLKGETGLRNKIEIKNMNSFSNMHVAIECEIKRQISAYMKHPNTPYHQIIQQSTYRWDPEKKETVIMRRKERADDYRYFPEPDLVPIVLTDSYIEEVRQSLPELPLQRERRYVAELGLSPHHAFVLTQDKPIADYFEEALKSCSNARNLCNWIIVEFAGRLKDSGKNLLTLGIPPIQLAKLVNMIDKGTITGRIAKTVADQMVAQPQMDCEKIVADNPDFKPVSDQGEIAAIVDRVLAQNPQSIADFKAGREKAFAFLVGQVMKETRGKAAPTVVNEMLKQRINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1R1</accession>
    <name>A0A0C1K1R1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">DB41_FH00020</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384112.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76621">
        <property type="protein sequence ID" value="KIC76621"/>
        <property type="gene ID" value="DB41_FH00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.657"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009740">
        <property type="term" value="P:gibberellic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0939">Gibberellin signaling pathway</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10 15" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF294" evidence="16">
        <location>
            <begin position="244"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="638"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="680"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="722"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="806"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="848"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="932"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="974"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="1058"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="1100"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="1142"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="1184"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="1268"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="1310"/>
            <end position="1343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KIC76621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1385" mass="156426" checksum="ABC81C25A53982C5" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1T0</accession>
    <name>A0A0C1K1T0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/alanine symporter AgcS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">agcS</name>
        <name evidence="9" type="ORF">DB41_DN00310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243779.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77010">
        <property type="protein sequence ID" value="KIC77010"/>
        <property type="gene ID" value="DB41_DN00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.323"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="465" mass="49124" checksum="A56C9D1C54796EAB" modified="2015-04-01" version="1">MATTHLELSSLLLHTLDNIYSWIWGAPLLILLVGVGLYLTIALKGLQFRYLPYALKIAFGRQKDVSGQGDISHFESLMTALAATIGIGNIAGVATAIAIGGLGALFWMWVTALIGMAIKYAEAILAVKYRKVDGRGEMCGGPMYFIEYGLGWKWLSVLFAIFGAIGTFGGGNMLQANSVADVMKNVFHIEPWVTGFIVALLTGATLLGGIKSIGKVAGLLVPFMAIIYIGGAGVILCKYYDRLPAALSHIFQYAFSGQAAFGGFAGSTMLMAIQVGVSRGLMTSEAGLGTASIAAAAAKTDLPGRQALVSMTGCFLATIVMCSATALVLGVTEVFGSLDAEGKLLNGASMTVAAFNQTFSGGAYVVTLGLVLFAFTTLLGWAYYGEKCVEYLLGSKSVPFYRAIFTLVVIPGAILELDVVWKISDICNGLMAFPNLIGLCALSKVVIAESRSFLKVLSHEQKGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Y2</accession>
    <name>A0A0C1K1Y2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DI00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383437.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77045">
        <property type="protein sequence ID" value="KIC77045"/>
        <property type="gene ID" value="DB41_DI00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043067">
        <property type="entry name" value="CcbP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020994">
        <property type="entry name" value="Uncharacterised_Ca-bd_CcbP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11535">
        <property type="entry name" value="Calci_bind_CcbP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7850" checksum="ADD573B9DE960B90" modified="2015-04-01" version="1">MTIPFKAKFIQSISTFPMEIDEIIEIVGVDDEESCEYDKFVQVKWKDKETLGVPLKQLKGINVDDKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K224</accession>
    <name>A0A0C1K224_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EU00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76721">
        <property type="protein sequence ID" value="KIC76721"/>
        <property type="gene ID" value="DB41_EU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="6204" checksum="96BB00432AF71D1B" modified="2015-04-01" version="1" fragment="single">TNKNLRLSEISFSYLLIKFPYAIWYFRLLAKLGVEGYERYTMQANKKFCFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K285</accession>
    <name>A0A0C1K285_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="13">2.7.8.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pgsA3</name>
        <name evidence="13" type="ORF">DB41_DB00120</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="13"/>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383354.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77105">
        <property type="protein sequence ID" value="KIC77105"/>
        <property type="gene ID" value="DB41_DB00120"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="169" mass="19196" checksum="C3C75323C3DB95EE" modified="2015-04-01" version="1">MLLSLPNLISFCRIPLAFLFLQENVFWRVIAILLAMLSDGLDGYLARRQKITTKFGTLLDPSTDKFFVIFVVIVLISEGRLMLWQAIALSCRDIAVLIFGVHLLLDKRLSHYQFRAIWCGKVTTCLQFIVLIGLTLQARIPDPFFITFILLGLLSLVELAIPRKKETVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2J2</accession>
    <name>A0A0C1K2J2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CP00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383173.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77230">
        <property type="protein sequence ID" value="KIC77230"/>
        <property type="gene ID" value="DB41_CP00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.90"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="10099" checksum="7DF1F2D93C0E82E6" modified="2015-04-01" version="1">MKELTFPVALIAKIFKNEDGSTGIQHRVTSNLDHDSDHIYEIYHQGWRIEEFHKSIKQNASLEKSPTKIARSQRDHIFSSPSRLLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2J4</accession>
    <name>A0A0C1K2J4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DW00080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383684.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76896">
        <property type="protein sequence ID" value="KIC76896"/>
        <property type="gene ID" value="DB41_DW00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="160"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="494"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="578" mass="65728" checksum="39EE2EC20D5BF55C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2K9</accession>
    <name>A0A0C1K2K9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77245">
        <property type="protein sequence ID" value="KIC77245"/>
        <property type="gene ID" value="DB41_CO00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="384" mass="45870" checksum="0399A24F6A6BB21C" modified="2015-04-01" version="1">MSPISLNSTYTSHEYYIDVNFLIRKSVRNIREGVGKGENLIELFHQTLDHLSLKCKELALKYGINKFDLQGVRRDQEECFTGVTYVTLMKKDLSHERLVTMIEELLQKIHYPTQSFKRYREEFPTEQGLKRHLSREITIYKEEELEIYSTPSFEECLRLCQLCSFSSPENPSQSLDLYQNLLTNKQAMLALKEKSFQDYQKLKLYSAILEIKHLYPRLVKVDWILVTQNLQVKGKRYELSEYLTWIFRDIENPIEKMKKEAMVTIIHQDPFLISPMLENIARIFKKAIRYNRYHLSLIKKQVALLRYELAHATPYKRGGNSISWWLERIIFNYHQYEPIYLNDPSINIEALTFPLKEFVEKYEEYMRVETMEANEEAKNRLNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2L7</accession>
    <name>A0A0C1K2L7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DS00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383630.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76936">
        <property type="protein sequence ID" value="KIC76936"/>
        <property type="gene ID" value="DB41_DS00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7285" checksum="5E8938FA7AE73501" modified="2015-04-01" version="1">MNSSHPITIEHLPNEILAPIIMAYASPSLFRVCTRWSHLLAKEIMPSLYKQISKMHVPQGNVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6Z8</accession>
    <name>A0A0C1K6Z8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75002">
        <property type="protein sequence ID" value="KIC75002"/>
        <property type="gene ID" value="DB41_HY00280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1422"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="557" mass="63765" checksum="20D56AB826BC999A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K980</accession>
    <name>A0A0C1K980_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppnK</name>
        <name evidence="5" type="synonym">nadK</name>
        <name evidence="6" type="ORF">DB41_HH00050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385197.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75712">
        <property type="protein sequence ID" value="KIC75712"/>
        <property type="gene ID" value="DB41_HH00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1202"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="283" mass="31499" checksum="F7109615EBCEF75D" modified="2015-04-01" version="1">MHIALFPNMIKKTSGEIAQQIAAFLKKRNAHVYAEDEVADEIDAAYLSSISPDKIDYIISLGGDGTILRVIQRHPELTAPLMAINFGGLGFMADIPIQETYKSLEDLLADKIVISERMMMAGKTEDNRTCYAVNDIIFHRAENPSLIEISIFVDDIYLNTYCADGIIVATPSGSTAYSMAAGGPILTPNLKAFVITPICPHTTSNRPIVLLPSHQIRIEYISKLKPIEVTYDGFSSFQMKTGEKFYLSSAQKKFRLVNMLHHDFYSTLRSKLGWSGKLKADEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9D7</accession>
    <name>A0A0C1K9D7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75787">
        <property type="protein sequence ID" value="KIC75787"/>
        <property type="gene ID" value="DB41_HE00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7997" checksum="ED37184FEBA91A2A" modified="2015-04-01" version="1">MIKKIPRPAIAKFFKRYYTLYKKIWQTRQEANPSKKANQAKLSLYKTLNLRPPRLKEAASSCKLKSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC01</accession>
    <name>A0A0C1KC01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_FH00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="KIC76627"/>
        <property type="gene ID" value="DB41_FH00080"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="DUF294" evidence="4">
        <location>
            <begin position="188"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="589"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="631"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="673"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="6">
        <location>
            <begin position="679"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="757"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="799"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="841"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="883"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="967"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1009"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1051"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1093" mass="124926" checksum="1B776722B74DCEE0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC94</accession>
    <name>A0A0C1KC94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative Na(+)/H(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">napA</name>
        <name evidence="6" type="ORF">DB41_EU00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383955.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000059.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76722">
        <property type="protein sequence ID" value="KIC76722"/>
        <property type="gene ID" value="DB41_EU00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.563"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="11"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="406" mass="44673" checksum="FF3F4322171538B1" modified="2015-04-01" version="1">MLIHNFFLQLVIILFMARVLGEFFARFNIPSVIGELFAGVLIGPSLFNLIEPNEMIKLLAEIGIILLLFEVGLETDMGRLAKTGSKPLIVAVGGVIIPFTLGFLVSYQLFDLSLIVSLFIASTLTATSIGITIRVLTDLKKQSSDEAQIVLGAAVIDDIIGIILLSILYEFSQGGGISFINIGKVLLFICLFLILAPIAAKFISNIIKHYEEKSEIPGLLPTTIVSLILLFAWLAHQMGAPALLGGFAAGLALSRQFFLPWGTYSPLNEEFSHKVETQMKPIVHLFTPLFFVTIGLSLNLSEINWGSTFIWLLSISILIVAIVGKLSSGFLLFKENKWIKWAVGIAMVPRGEVGLIFAEVGKDSKIFDNDLYASMIIVIAITTVFTPFFMRFFYNLQAQAENEVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCC8</accession>
    <name>A0A0C1KCC8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">infB</name>
        <name evidence="11" type="ORF">DB41_EO00050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383890.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76752">
        <property type="protein sequence ID" value="KIC76752"/>
        <property type="gene ID" value="DB41_EO00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.537"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
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        <location>
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            <end position="325"/>
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            <begin position="426"/>
            <end position="574"/>
        </location>
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            <begin position="31"/>
            <end position="46"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
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            <begin position="432"/>
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        </ligand>
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        <location>
            <begin position="478"/>
            <end position="482"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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        <location>
            <begin position="532"/>
            <end position="535"/>
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        <ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KIC76752.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="922" mass="101249" checksum="E0BA78CA4CDADB82" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE59</accession>
    <name>A0A0C1KE59_9BACT</name>
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        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
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            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="gene ID" value="DB41_CO00260"/>
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            <begin position="1"/>
            <end position="23"/>
        </location>
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            <begin position="590"/>
            <end position="642"/>
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            <begin position="80"/>
            <end position="145"/>
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            <end position="330"/>
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            <end position="436"/>
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            <begin position="479"/>
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            <dbReference type="EMBL" id="KIC77257.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="642" mass="74755" checksum="548AE6385D06B8A5" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
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                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
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            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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            <end position="141"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="359" mass="40178" checksum="3C1C2CB636F95FBF" modified="2015-04-01" version="1">MEALMKIHDLSQACCSIDNIADYIPLVSTVTNLVDIFQKCVLLHFNPEQSSSESPYYAHLRLKSFKRCIILLIPILGNISIGIYDFTCRKSKGKKTVTPNVELKSLALQNSNKEIKNNKRLILAIVKQNGWALEYVNEQFKDDKDIVLAAVKQKGMALQYASENLKNNKSVVLAAVQQDGWALEHASKELQNDKRVVLAAVRQDGSTLQEISQELRNTKEIVLAAVQQNGWALQYANEKLKNNKEIVLEAVRQNGWAIQYASEQLKNNEDVVLAALEQNGLALEYIGPALKDKKNVVLVALKQNGLALEYASQNFKNDENMVLTAVQQNGKALRHASYGLQKNKKLINLVKKQSSPLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KEA7</accession>
    <name>A0A0C1KEA7_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Parachlamydiaceae</taxon>
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        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
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            <authorList>
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                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77302">
        <property type="protein sequence ID" value="KIC77302"/>
        <property type="gene ID" value="DB41_CJ00120"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
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    </dbReference>
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        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
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        <property type="match status" value="3"/>
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        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
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        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="656" mass="73594" checksum="20F7469C21AFF337" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H199</accession>
    <name>A0A0C1H199_9BACT</name>
    <protein>
        <submittedName>
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            <taxon>Parachlamydiaceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
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                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000219">
        <property type="protein sequence ID" value="KIC71504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71504">
        <property type="protein sequence ID" value="KIC71504"/>
        <property type="gene ID" value="DB41_AX00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="193" mass="21787" checksum="F8645E21793EB6BF" modified="2015-04-01" version="1">MIHLGTIDSLQAEVILPEAYLHCSRQDLLDCHRLLPQPPWHQAHPPSSRVFPRPNLFMKRLSLSCTPNMKSKLCNKAARAYPPVLVRVVTPLYHKYPTHLIHSSSFDKSSSPTFIVTLPIIGVHSFISRTQDKLDKEELEQTQSQEIFSPPLQTRPPSPPKTTTPATTLSIVKLPPIPTPPEPTTRYPFPHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H299</accession>
    <name>A0A0C1H299_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AI00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71804">
        <property type="protein sequence ID" value="KIC71804"/>
        <property type="gene ID" value="DB41_AI00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="14284" checksum="4ED4A388111ED612" modified="2015-04-01" version="1">MIRCLMHPLTHSVVAELIPRKEVNILDQKMLEKLTITGTTVSSEFKNLHRVGWRVYPNENKEVFTKTFEQFYFMHGLQQQGYCWENKREVEVPTEKLAQSILSHYYASLQPPPDSDSLSNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3Y4</accession>
    <name>A0A0C1H3Y4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_KQ00090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386480.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72244">
        <property type="protein sequence ID" value="KIC72244"/>
        <property type="gene ID" value="DB41_KQ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2013"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="348" mass="41079" checksum="5B2D500A17AB02AF" modified="2015-04-01" version="1">MSSSRIEGETYFQANTFFYNDHINPIIASIIPQFEGMMRSYVILHLIFLILGGIECILMVTFFSLLTQSALLAMCLAGVFLTFFSYFILKVYYQTKKPEQHKEIIQRYLSACKSLLNYQEGCPEHHIALANACCKLANNLHGKEYNFYAFPQWLKSLHSFIEKFSCWWHWQDVHRFKELLLLTSVEENIKLVKCEPTSLEVHASLANAYVMLSGLYVDPRKLEGYDEERWMPVERYSFQMEEKFRAIAERAIEEFKVLNDYAPNDPWVHAQLAYSYRDLQMPKEEIKEYETILKLNPGDRETFYKLGLLYFQQGFNAQGLRVYEELKRTHYKKAESLMENYGLFKPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H447</accession>
    <name>A0A0C1H447_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein CicA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cicA</name>
        <name evidence="1" type="ORF">DB41_KO00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386440.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72319">
        <property type="protein sequence ID" value="KIC72319"/>
        <property type="gene ID" value="DB41_KO00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="203" mass="23480" checksum="1F2147E34B9B0C05" modified="2015-04-01" version="1">MANPSPSIIAAFDFDGTLTYRDSLLPFLNFVVGSALKRKNLCLESFHFFQYLLGYLSRQQLKEALLTRFLKGKERHEIKMYAERYAKEILPTLLRPQAIERIRWHKNQGHRCVLISANLDIYLKPWGQAVGFDNIIASRVAFSPQGYLTGYLQGLNCRGAEKVRRLIEEEGPTKNYILYAYGDSQGDQELLQCANFSFYRRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8G5</accession>
    <name>A0A0C1H8G5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CE00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000250">
        <property type="protein sequence ID" value="KIC71163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71163">
        <property type="protein sequence ID" value="KIC71163"/>
        <property type="gene ID" value="DB41_CE00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="185" mass="20105" checksum="C52F2A16439CA963" modified="2015-04-01" version="1">MFERVPCWYACTRVRGIYRIPSGVSLASVRAFVGAWAVRVAFVRVGDLRRLGVCACVCLRDAFVSAFARVAEGALARVSVRLCVGAIVRAWGRICCQNRKVIFRRLEGSNGHNGQGRGRGRARWIGQAAVHIGRQREGRTSQPLASKNQNTEMAGRSWPGGPDFGEASVQTEHGRTNAPIACGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9Z2</accession>
    <name>A0A0C1H9Z2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AS00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71653">
        <property type="protein sequence ID" value="KIC71653"/>
        <property type="gene ID" value="DB41_AS00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="6052" checksum="206003878C8B3584" modified="2015-04-01" version="1">MKRAKREEKRLPTRLGRVIRGFEGKTEEQAFKQKALFFRKYQAYLCSTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAK1</accession>
    <name>A0A0C1HAK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative RNA methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rumA</name>
        <name evidence="7" type="ORF">DB41_IP00140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386030.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74414">
        <property type="protein sequence ID" value="KIC74414"/>
        <property type="gene ID" value="DB41_IP00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1644"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="428" mass="48426" checksum="65992D001232D964" modified="2015-04-01" version="1">MSEILVGKVVALNSEGQGIVREDNLVIFIPFTTPGDTIRYHIVKRKKNFATGKLLAVLKPSLQRVKPLCRYYGECGGCQLQHLTYEAQLENKRQIIENALIRIGKFSKLAVLPVVAAQMNWMYRRHITLKIIPHQGFFRAGYIAIDNQTLLPIQHCPLFLAEDNVALAEVQTLLGKISSQQATEGRATLFKTEVNQLILSLNFEKLNKIEAEIIEEFLKQFPRWKGVIVKGGSKKWVWGDPTNFLEVGHLKFLCSPEVFIQNHAEQSLKIYQQIIDLFSKKKQATILDLYCGIGISSLLLSQQGHRVIGIEYNPLAIAMAKENACLNRLTTPQFIEGDVEKVLQKELHEQHADIIILNPPRQGITPAVGVEILRRCPQEIIYVSCMPSTLARDLSLICVQGYRISLIQPYDMFPQTSHVETLVHLIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAL6</accession>
    <name>A0A0C1HAL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IO00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000146">
        <property type="protein sequence ID" value="KIC74439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243996.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000146.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74439">
        <property type="protein sequence ID" value="KIC74439"/>
        <property type="gene ID" value="DB41_IO00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7447" checksum="57B4418B1AFB2FFF" modified="2015-04-01" version="1">MHLVKIGLTLLSTEIGQLVQLEGLFLNNNKLTTLPAEIGHLSHELDLDLGGNLLRSIPNEIKQCFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBM0</accession>
    <name>A0A0C1HBM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein YlmG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ylmG</name>
        <name evidence="3" type="ORF">DB41_KR00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386519.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72188">
        <property type="protein sequence ID" value="KIC72188"/>
        <property type="gene ID" value="DB41_KR00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2041"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="PTHR33219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="9997" checksum="D5F72D7861DC53DF" modified="2015-04-01" version="1">MWLIPIVDLLFQIYMLMLFGRIISSWAPQLMQYRFMQFIAFYTDPYLNLFRKIIPPFGMVDISPILAFFSLNLLKDLIIFLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBN8</accession>
    <name>A0A0C1HBN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IE00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000139">
        <property type="protein sequence ID" value="KIC74839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74839">
        <property type="protein sequence ID" value="KIC74839"/>
        <property type="gene ID" value="DB41_IE00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7472" checksum="A0C107D9CA899561" modified="2015-04-01" version="1">MAHHHASYYKLFLNKCFLENKLSVALFSFFPLTYKKLQVAKRINFSNKRKGFQSAYFFPYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBR2</accession>
    <name>A0A0C1HBR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KQ00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72238">
        <property type="protein sequence ID" value="KIC72238"/>
        <property type="gene ID" value="DB41_KQ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2006"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="584" mass="65354" checksum="9F77019D82022FE2" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBY1</accession>
    <name>A0A0C1HBY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KO00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72313">
        <property type="protein sequence ID" value="KIC72313"/>
        <property type="gene ID" value="DB41_KO00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1979"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="377" mass="41202" checksum="D92C5B8F699C4F13" modified="2015-04-01" version="1">MSKALQTNNSLTLLILNDNQIGYEGTSALGKALETNISLTVLNLKGNEIGFEGVSALAKALEINHSLSALDLYNSEIAYEVASPLAKAEAARALAKAEGASVLAKALETNNSLTALNLYNHEIGNEGASALGKALETNTSLTQLNLRSNRIGYDGFSALAKALETNISLTELNLSGKNFISYEAIKALAKALETNTSLTSLGLSWNINSKNPTLAFIRESLRKNQTQRQPLEGQKFQAASLAKKLNSSHDKKALKHEVNYLPQADHTLSTENFLPGERRVLDSLSADSVSLLALQLWNVLNGYFASSDFQEANDEIKRTTAHFQIQLLDLQHCDYSLFSQQKLQQAQSYLINISSYLAHKKIISPDYLLTGKKENKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC16</accession>
    <name>A0A0C1HC16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative D-alanine/glycine transport protein, sodium-dependent</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dagA</name>
        <name evidence="9" type="ORF">DB41_IB00920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243980.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74959">
        <property type="protein sequence ID" value="KIC74959"/>
        <property type="gene ID" value="DB41_IB00920"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1526"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="455" mass="50056" checksum="961D08C8BCA3521D" modified="2015-04-01" version="1">MLDNFFIHLEQVENILWGYVAVPTILLLGVFLSFQARWVQIVQFPRVVKTFFGFLFVPDKDKSGVHPLQAFFACVGGCVGIGNIVGITTAVQIGGPGALLWIWLTAIAGMMIKYSEVYLGIRYRVPNAHGGYNGGPMYFLQRVFKGSFVPTIVGGLLCIYGVEVYQFNVIVKSVTANVNLSPYLVLAILLALVIFAGQGGVRRVGNISGISIPLFVFVYLGMGCWVLIQNIDRIPEVLKAVFNTAFTGHAAVGGFIGSSAMGTISQGVRRGCYTGDLGVGYASVIHSESFVKIPEKQASLVIFDIFVDTFMICTTSILIILVTDLWHQPINSSLLIQTALAQYFPYMEWFMPLFLFLLGYSTINAYFCVGLKCAEYLHPRKGRKLYYIYAVITLGAFALVDTAQAQTVMTIAGGLLLVLNCYGIFKLRHEISYNFNFLQNEKTEGRSIAVSADLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE79</accession>
    <name>A0A0C1HE79_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8 10">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">apbE</name>
        <name evidence="12" type="ORF">DB41_HH00220</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the ApbE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="2 8 10"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75729">
        <property type="protein sequence ID" value="KIC75729"/>
        <property type="gene ID" value="DB41_HH00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1220"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC75729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="352" mass="39931" checksum="5DF0401D4C5EA3C1" modified="2015-04-01" version="1">MELWCYTKDKLKKYYTFSYFFILLFLLYSCSNSTHEKLTLFSGNEMTINYRILIGHPLSASEKALVSKIIRDTFEEVNHIYNKWNPFSELSCLNQLKAGTVVSISTELEQLLNLTDKIVLLSEGRFDPTIEPLQALWKKHLEQGQIPSEGAILSVAATIGWNKIHFGQGKFHKDLDDIQLDLGGIAKGYCVDLLTDRLYEAGYTNLFVEWGGEIKTMGEHPQGRPWNIFISRLGNINPENAIAKINLRNQAIATSGDYFQSWAIKAKKGDNAYHTTTYFHILDPVNLTPLIITRENVASASVLAPSCALADGLATTALMFRSKEEAHRWADKITHDYPEIAFWIVSREDLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEA3</accession>
    <name>A0A0C1HEA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HG00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385171.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75759">
        <property type="protein sequence ID" value="KIC75759"/>
        <property type="gene ID" value="DB41_HG00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1080" mass="123080" checksum="FC50DB36629A2D0F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HED9</accession>
    <name>A0A0C1HED9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385094.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75799">
        <property type="protein sequence ID" value="KIC75799"/>
        <property type="gene ID" value="DB41_HE00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1149"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="79" mass="8842" checksum="F517CAC95951197F" modified="2015-04-01" version="1">MYDVTSSYLEGEKNKLADWGYNRDKKKGKKQIVIGLLSSAEGAPVSAEVFKGHTQDTSTFHAQIKKAKERFNCEKVTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEG6</accession>
    <name>A0A0C1HEG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0701 protein YloC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yloC</name>
        <name evidence="3" type="ORF">DB41_HC00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000113">
        <property type="protein sequence ID" value="KIC75829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75829">
        <property type="protein sequence ID" value="KIC75829"/>
        <property type="gene ID" value="DB41_HC00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005229">
        <property type="entry name" value="CHP00255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013551">
        <property type="entry name" value="DUF1732"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013527">
        <property type="entry name" value="YicC-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30636">
        <property type="entry name" value="PTHR30636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08340">
        <property type="entry name" value="DUF1732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03755">
        <property type="entry name" value="YicC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00255">
        <property type="entry name" value="TIGR00255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YicC_N" evidence="1">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1732" evidence="2">
        <location>
            <begin position="211"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="295" mass="33916" checksum="E3B88CF5617910BE" modified="2015-04-01" version="1">MLRSMTAYGRGAIETALGRFTAEIQSVNRKHLEINVLLPKELMRFDAEIKKWISARIGRGQITVKFSVVFNQTTPLNVVANLPLALKIQKAAEDLAFTLKLPVTHELTLKMLAEQPSILLFDEQMDDEELYREALSTAFEKAMQSFVEMKLHGGCPIFIDISQGLETLHQDIEQIAYYAPQATKRYREKLAERLKEFSIGPREDEERLLREIGIYAERIDISEEITLFQAHLKQFKDVLSSQKEAVAKKLEFILQELNREINTIGAKSSELEVSRRVVEIKSLLERIREIIQNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEX1</accession>
    <name>A0A0C1HEX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JM00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73248">
        <property type="protein sequence ID" value="KIC73248"/>
        <property type="gene ID" value="DB41_JM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="5790" checksum="12DADF78F336EA29" modified="2015-04-01" version="1" fragment="single">MYQIMVGLGLLISFWLLTPPSVQTAELKFNILSELNGKGLEADQKILSRALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG94</accession>
    <name>A0A0C1HG94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GG00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384601.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76394">
        <property type="protein sequence ID" value="KIC76394"/>
        <property type="gene ID" value="DB41_GG00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8144" checksum="9E8E80DE4AF3E209" modified="2015-04-01" version="1">MELKQIAKAIKKVSNMSKLFKGLKKGLEEALAFSERKVTLKSELIEIPEPLNKYKAIDIKRIREKNHYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGP0</accession>
    <name>A0A0C1HGP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hemN</name>
        <name evidence="11" type="ORF">DB41_FX00080</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384389.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76499">
        <property type="protein sequence ID" value="KIC76499"/>
        <property type="gene ID" value="DB41_FX00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.788"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="2"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="381" mass="43613" checksum="EFE18A78D7EB0724" modified="2015-04-01" version="1">MPSPKEPISLYFHVPFCTHKCGYCHFYVLPNRQDLKNIFMQALAKEWSLRLPDLMDKEIVSIYFGGGTPSLLGVEYLGEIIEWIKRDVNFDPLTTEITLEANPETITFSLMQAYALAGVNRVSIGIQTLSNTLLEKLERQHSAEKAIEAVWASYEAGLKNLTVDLMYDLPNQTLAIWKETLLQVSKLPIKHLSLYNLTIEPHTTFFKYRDLLLKTLPDPDLSLQMYELAQAMLNSCDLKQYEISAFAQEGFQSKHNTGYWAGRSFLGLGPSAFSYWKGKRFRNIAHLNRYAYLLNNGNFPLDFEEQLDPEASQRELLAIRLRMREGIDLKTFQQAHGALSQETLQNLTCLEEQGFINKESSRISLSQQGVLFYDTVATELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGR0</accession>
    <name>A0A0C1HGR0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">potA</name>
        <name evidence="10" type="ORF">DB41_FU00090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384339.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76524">
        <property type="protein sequence ID" value="KIC76524"/>
        <property type="gene ID" value="DB41_FU00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.768"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015594">
        <property type="term" value="F:ABC-type putrescine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03300">
        <property type="entry name" value="ABC_PotA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017879">
        <property type="entry name" value="PotA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="376" mass="42944" checksum="F7FA8028BCD0DF1F" modified="2015-04-01" version="1">MADSLEFIGISKEFGNVKALQDVTFSIKKGEFFSLLGPSGCGKTSLLRIVAGFERPTQGKILLDGQDITHIPPHQRPVNTVFQNYALFPHLNIWENIAFGLRVAKRSQKEIDFEVDRMLHLIQLKELAYKMPDQISGGQKQRVAIARALINKPRVLLLDEPLAALDLKLRQKMLLELDLIHDEVGITFLFITHDQTEAMAVSDRIAVLRQGSLEQIGTPIELYEAPKSSFVAAFIGDTNFLDGHVAEKVSQDYSLLTLDNFPNVLCFNDKQLNVGDLVHLSVRPEKMHISREQPPHHPRHNQVPGVVEDVVYKGAHTNFWVRVEGHRIAVTQQHRRFLLDEHPIRWNDKVWIWWHADDGFILERYNPQVSIEKQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH00</accession>
    <name>A0A0C1HH00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_IS66 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FK00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76584">
        <property type="protein sequence ID" value="KIC76584"/>
        <property type="gene ID" value="DB41_FK00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="60" mass="6833" checksum="A865F9C77080B563" modified="2015-04-01" version="1">MGKAIFYLNIHGEAFTLFLRIPGIPLTNNIAEQIMKKAALNRKIAYFFRNETEAIIATSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHN4</accession>
    <name>A0A0C1HHN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EH00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383784.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76824">
        <property type="protein sequence ID" value="KIC76824"/>
        <property type="gene ID" value="DB41_EH00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="305" mass="33169" checksum="6789961E92C09A0C" modified="2015-04-01" version="1">MQAINSATLNLTFLPSPDSSVAKDTLLGYDIKSTWVELKAFFIDLFQVIAQVFAERSFFGKVFKLSIHLLTGLACIRGNTYQGARLLGALSATDSLLTLGDLAIDANDLVNKRYCEIEENSKNKKVFNKWSLFASIGSLLADIGGLFFWLDELALINLLKVKATIGKNFSRLVNSNTMLFTYLTNCLGRMSPMFAKISLVIGLQGIEAMAILCLSVNEVKHLANVVDTKQTYKIVLSIVNLASYIAEINLKILATTGYIAVPGIAAMGCAAAGCGLAAFLLEAIYNYRLVNLQSKRPAAGSWIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI15</accession>
    <name>A0A0C1HI15_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 15">3-dehydroquinate synthase</fullName>
            <shortName evidence="15">DHQS</shortName>
            <ecNumber evidence="7 15">4.2.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15 17" type="primary">aroB</name>
        <name evidence="17" type="ORF">DB41_DP00110</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 15">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 15">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 15">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="7 15"/>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76959">
        <property type="protein sequence ID" value="KIC76959"/>
        <property type="gene ID" value="DB41_DP00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.344"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="14 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 15 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0520">NAD</keyword>
    <keyword evidence="10 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="16">
        <location>
            <begin position="75"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="113"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00017684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KIC76959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="373" mass="41655" checksum="52A2DECFFB08B609" modified="2015-04-01" version="1">MRKLRDMDPLSFSQWTSINLASQDSSILINPVPLFTDLQLKKDYSQLVIISDANVYPLYGPFLIQQFPCRQINKIIIAPGERSKSLQTANYCWQELQRFEIDRHALIISLGGGVVTDLAGFVASCYMRGLDIIHVPTTLMGMVDAAIGGKTAVNFKGSKNLIGSIHPPRQVWIFSSYLQSLPAEEFSAGLAEIVKYGIIQGPQLFERLEKNTTAILAKDSQFMHLLIVECCKIKAFIVEKDERDYGIRATLNLGHTFAHAIEAAMDYQISHGHAVSIGLSCAFYTSKILGFIEQALIIRLHNLLKSLNLPLSLPEELSEETLISYMYKDKKTVKGKLNLILVKKIGSVESIEAVEPKVILTALKQKKAEKELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIP0</accession>
    <name>A0A0C1HIP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acidPPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DB00210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383366.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77114">
        <property type="protein sequence ID" value="KIC77114"/>
        <property type="gene ID" value="DB41_DB00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="85"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="232" mass="27047" checksum="DEA547FE7E839E45" modified="2015-04-01" version="1">MLHSSNRSLWLIPLISIFLLTPFSSTLDLAIARYFFDNGHFQSNSFLNFLYSYGMVPGWILTLFALLFLVLSYLHPFWKCWRPYALIPLLTMIVGAGIIVDLSLKGHWGRPRPKQLEEFGGIQHFRPFYQPNFFHQPEPSKSFPSGHCSMGFVFLSLTLIGRRLRQRWLYWCGTFTSAILGALLGYTRMAQGGHFFTDVIFAAAFMWWTALFFDWLIFEQRIADEKFDKETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIT3</accession>
    <name>A0A0C1HIT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="4 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pgd</name>
        <name evidence="10" type="ORF">DB41_CV00120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="4 8"/>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383261.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77174">
        <property type="protein sequence ID" value="KIC77174"/>
        <property type="gene ID" value="DB41_CV00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.139"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="9">
        <location>
            <begin position="180"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="187"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="33"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="75"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="483" mass="53147" checksum="3A44A2D6C7E43172" modified="2015-04-01" version="1">MGQADIGLIGLAVMGQNLALNMNDHGFIVTVYNRTRATIDSFLNGPAQGSKIISASTIEEFCQSLKRPRKVILMVKAGEPVDACIQQLIPYLEPGDVIIDGGNSLFSDTNRRTQALKEKGLLFIGSGISGGEEGARHGPSIMPGGNPEAWPLVKNIFQSISAKADNGEPCCDWVGDEGAGHYVKMVHNGIEYGDMQLICEAYSLLKHALKLNPQQIAQVFAQWNKTELDSYLIEITSAIFKQLDEDGQPLIDKILDVAGQKGTGKWTVINALEVGMPLTLIGEAVFARCLSAIKEERLEASRVLTGPSPLYEGDQEAFIESIRQALYASKIISYAQGFMLIQQAAKDYHWRINFGGVALMWRGGCIIRSKFLNNIKDAYEKQPALKTLLLDDFFKNALVKAQSDWRRVVAKAVELGIPTPCFSTALAFYDGYRSPNLPANLLQAQRDYFGAHTYERLDHPRGQYFHTNWTGTGGKVSSTSYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ00</accession>
    <name>A0A0C1HJ00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_CO00130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77244">
        <property type="protein sequence ID" value="KIC77244"/>
        <property type="gene ID" value="DB41_CO00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.47"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="Purple_acid_Pase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="SSF49363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002151171" evidence="2">
        <location>
            <begin position="23"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Pur_ac_phosph_N" evidence="4">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="3">
        <location>
            <begin position="123"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="404" mass="46752" checksum="9B2654C73CE24FB9" modified="2015-04-01" version="1">MQTFLFILSCCFIFLFPCSMWADEEILSIYLTWQHHPQSTMHVCWITPQTQTQDLIEYQREGEEVWHREESQHRPMPAQLPYLIHRVELVGLMPSTGYRFRLGADKHIYKFRTMPADSNLPIRFVVGGDMYNGSMEMMEKTNRAAAATNPLFVVIGGDIAYSAVGDRSIPENPQKWIDWLRIWKQTMVTSEGYLIPIIPCIGNHEVRGGNGKTPQEAEFFFALFPTPDLKSYKVLDFSSYMSLIILDSGHAYPVRGVQTLWLKQVLRQRRQVPHKFAVYHIPAYPSYRSYYNKTSRAVRRQWVPLFEQYGLHVAFENNDHAYKRTHPICKGRPQKQGVLYVGDGAWSVANIRTPKTPRQAWYIAKSSATQFFILVTIDGSHRRMQAFTPAGMIVDDVVQEGFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL29</accession>
    <name>A0A0C1HL29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75103">
        <property type="protein sequence ID" value="KIC75103"/>
        <property type="gene ID" value="DB41_HW00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8482" checksum="896CFEEF2F28B375" modified="2015-04-01" version="1">MQKDKGKASSYTILEVQINASEKEIKNAHKKIICIIIQIRIQRDPMKVSRITQLEKKRERKNLKKSRGHLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLR9</accession>
    <name>A0A0C1HLR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HP00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000126">
        <property type="protein sequence ID" value="KIC75348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385405.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000126.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75348">
        <property type="protein sequence ID" value="KIC75348"/>
        <property type="gene ID" value="DB41_HP00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="183" mass="21179" checksum="80D9ACDA0AB72D39" modified="2015-04-01" version="1">MNKTYFLFFFILMFTLSSCMLSVLDSYEEPEQAVFVSDILNKTSKKLQKKYSMRTIGTGIGMPDGVVTMLALSFEKTGPLSREEGRRIIVDCVQEMLQIINTHERIRPHLKNYPFTPSDIEIAIFLKDPLGYNIFYPHFGALSSTNAQIDYMFTASENPKRYLKIEEEKFEEALEMVQNESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNU8</accession>
    <name>A0A0C1HNU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipid A export ATP-binding/permease protein MsbA</fullName>
            <ecNumber evidence="11">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">msbA</name>
        <name evidence="11" type="ORF">DB41_GU00170</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243913.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75968">
        <property type="protein sequence ID" value="KIC75968"/>
        <property type="gene ID" value="DB41_GU00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1037"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="67"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="92"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="399"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="431"/>
            <end position="438"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="639" mass="72515" checksum="20F5C6D8B7937A71" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPZ4</accession>
    <name>A0A0C1HPZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acyl-CoA thioester hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GL00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243890.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76273">
        <property type="protein sequence ID" value="KIC76273"/>
        <property type="gene ID" value="DB41_GL00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.948"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="26"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="237" mass="27089" checksum="F2A55175857C02E8" modified="2015-04-01" version="1">MTKIHALHGFLGLPTDWQMFNLPNLHAYSLRRPSLAPAADGLWGWAKRFNRLTQPRHDDILMGYSLGGRLALHALLDNPNQWRAGIIISAHPGLTSKEEKIRRVQADKAWADRFGNDPWQDVIRDWNCQAVFGGKSFPVKRSEHQFLRKNLQDQLRFFSTGHQDDLSEALKDLPLPILWISGQLDIKFLAKAHELAFSHPLSRVESIAHAGHRAPWEQSILFLKIIQSFIQEVLSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQN8</accession>
    <name>A0A0C1HQN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA_pol_A_CTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FX00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243857.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76493">
        <property type="protein sequence ID" value="KIC76493"/>
        <property type="gene ID" value="DB41_FX00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_pol_A_CTD" evidence="2">
        <location>
            <begin position="103"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="399" mass="46288" checksum="A538C7BAAA501B5E" modified="2015-04-01" version="1">MAVLEFKQETNLSPSKGHRKRSTEPSSTTLLSFEETYKTSYSHGLENIYALENVDINSIRRIGTLSPTAPPPLKNKKELFTGEEDELDLGEEFRGWIPSFIPKVPIQVLELSKYIEKALLENGKKTIGDLTKASIDDFVFLRGIGQGHLEEINRKLNSYLESRSLGKCKKVDFLAWLQSLVATQERKKAYALLEPYNLTELFVLSPSEKVELRQLSLEKKQEWIQEVVNKMATPLQKQRVLEDMQLIFNVFFKPWIRRRGGIATRHELIERMQRISANKAMGISVVNFLQTHFFDSKDCLSLFLQEIEEEIYACDHHSIQEYGEIISKALSYFYKPSIYYRLTELITWVEKELAKAWIGYHEGYVEKIIRLSPTFDIVRGASGQLEVYCRKYFSITNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR73</accession>
    <name>A0A0C1HR73_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">gatC</name>
        <name evidence="2" type="ORF">DB41_FI00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384189.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76618">
        <property type="protein sequence ID" value="KIC76618"/>
        <property type="gene ID" value="DB41_FI00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15004">
        <property type="entry name" value="PTHR15004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="11216" checksum="FBDA6A6ECD65B8E5" modified="2015-04-01" version="1">MAHIDKDTIQNLMALSRIECTEEQKEVLLNNLKKIIGYFEQLNEINTDDVPPCDHVLADMYNVMREDVPGPTLPREKFLSNAPAHIGGMIKVPTVIKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRN4</accession>
    <name>A0A0C1HRN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpmC</name>
        <name evidence="6" type="ORF">DB41_EI00030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383808.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76788">
        <property type="protein sequence ID" value="KIC76788"/>
        <property type="gene ID" value="DB41_EI00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7859" checksum="E29C7CFF05C378EA" modified="2015-04-01" version="1">MKKAKDFRDQSLEDLEANCKDARRDLFNLINEMKQSNKVEKPHLVRHKKREIALLLTVINEKKRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRT4</accession>
    <name>A0A0C1HRT4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsS</name>
        <name evidence="8" type="ORF">DB41_EH00170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383797.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76833">
        <property type="protein sequence ID" value="KIC76833"/>
        <property type="gene ID" value="DB41_EH00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.482"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10593" checksum="17EAA30C8D8328AB" modified="2015-04-01" version="1">MARSLKKGPFIDHHLHKKVEDMNGKGGKTPIKTWSRRSMIIPEMIGHTFEVHNGKKFISVFVSENMVGHRLGEFSPTRNFKGHPIKKAEAQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSR7</accession>
    <name>A0A0C1HSR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative exopolysaccharide synthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">exoD</name>
        <name evidence="2" type="ORF">DB41_DC00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383379.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77088">
        <property type="protein sequence ID" value="KIC77088"/>
        <property type="gene ID" value="DB41_DC00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010331">
        <property type="entry name" value="ExoD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41795">
        <property type="entry name" value="PTHR41795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06055">
        <property type="entry name" value="ExoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033239">
        <property type="entry name" value="ExoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="23498" checksum="B1BFDB6A38C40764" modified="2015-04-01" version="1">MLKKCSSLAEKLENLLNQTHSEELSVQKIMDHLADQGYATLLIVLSLPFCSPMQIPGLSTLLGLLILLIGLKIAFGHKVWLPKRLLQKKIPFLFLKKVMFYVLKIDTKLGFLISTRWVGLVRNRYLHIIHGLTIAVLAFFLSLPLPIPFTNLLAALPLLAFGLAFLEDDGFFILIAYFFAFICLLSFAAIIWFGIDWLIVWKKYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT19</accession>
    <name>A0A0C1HT19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CR00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383194.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77213">
        <property type="protein sequence ID" value="KIC77213"/>
        <property type="gene ID" value="DB41_CR00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.99"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="797" mass="92045" checksum="0CBCA4B96AFB54BB" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT24</accession>
    <name>A0A0C1HT24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative ATP-dependent Clp protease ATP-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">clpC</name>
        <name evidence="10" type="ORF">DB41_CP00030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243741.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77218">
        <property type="protein sequence ID" value="KIC77218"/>
        <property type="gene ID" value="DB41_CP00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.78"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="9">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="8">
        <location>
            <begin position="447"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="152"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="443"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="855" mass="96045" checksum="2BE812D5E920D6D9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKC4</accession>
    <name>A0A0C1JKC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AM00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71740">
        <property type="protein sequence ID" value="KIC71740"/>
        <property type="gene ID" value="DB41_AM00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="53" mass="6212" checksum="6AC85FD7A507C877" modified="2015-04-01" version="1">MGFLQLLQIKYSFNIHFSQMQVFLLSFLFFREKFSVGSHFTLGKGGHSLLRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLU9</accession>
    <name>A0A0C1JLU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative acylase and diesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KQ00150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386488.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72250">
        <property type="protein sequence ID" value="KIC72250"/>
        <property type="gene ID" value="DB41_KQ00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2020"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002152231" evidence="1">
        <location>
            <begin position="20"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="292"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="544" mass="60564" checksum="572F0891893783BC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM13</accession>
    <name>A0A0C1JM13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_AV00210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386918.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71581">
        <property type="protein sequence ID" value="KIC71581"/>
        <property type="gene ID" value="DB41_AV00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="403"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="448" mass="50721" checksum="268D19658C30334D" modified="2015-04-01" version="1">MNLDNLHLKYIRRLILVLTASGALNIILLSLFFYWFIKDAPPPLYFEQKPALKQEQQVPLASTKGNIELIHYFRSLSFDELVARLSNHQLIENGYTQRDIALACLVAFHHFDLSRALLGQPPLAQQRSIIYGQLKSGQPAMITVYPGLSDENFQAVIQFANTERWPLTSKGLFLQLKKFKEREDASLSDAFFMTSEFLAVEWLFNRAEMPVSKIELQNMLLDGTWGMLSGFAEQQKIVQDLSAARRQRFLLEYVDGQSKHAAYLLLKVDGEFALNKLDDYHVLALLALLEDKTSESEKYALDLLDRPRSDNVWKAAGAKLYQYAGELIPENNLPHGAMKRFILGASSAEVPLKKPIIRENPSKPLVPLSPPPPTPFNSSPKKPASQTLAPKAPKSPTSFPSDRLYIVQEGDSLWKISRRFKVDIEVLRDYNKLKTDALKPGTPLRIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM17</accession>
    <name>A0A0C1JM17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D</fullName>
            <ecNumber evidence="3">3.1.4.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">napEpld</name>
        <name evidence="3" type="ORF">DB41_KO00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.54" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72320">
        <property type="protein sequence ID" value="KIC72320"/>
        <property type="gene ID" value="DB41_KO00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102200">
        <property type="term" value="F:N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="374"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="612" mass="71762" checksum="0C0D8BCC858FFBEB" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMD5</accession>
    <name>A0A0C1JMD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Type III secretion outer membrane ring component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sctC-B</name>
        <name evidence="6" type="ORF">DB41_AQ00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial secretin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71716">
        <property type="protein sequence ID" value="KIC71716"/>
        <property type="gene ID" value="DB41_AQ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Secretin_N" evidence="5">
        <location>
            <begin position="614"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC71716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1005" mass="109285" checksum="20FC7308931B7FDE" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMY6</accession>
    <name>A0A0C1JMY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386655.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71936">
        <property type="protein sequence ID" value="KIC71936"/>
        <property type="gene ID" value="DB41_AE00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="129" mass="15048" checksum="479055D80CFF8AD0" modified="2015-04-01" version="1">MNYILFLIAILSCLSRLVAAEPLYNLKETEPTVVVKNELKRLDQLIFVTEMNLEQQKALRELFLYYQDRQSSYLQSPQDKESTLHMVRAAYQLLEAIKANHLLQTFDTEFISQLTFFSQFATKQGIPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNW7</accession>
    <name>A0A0C1JNW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_JZ00020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000182">
        <property type="protein sequence ID" value="KIC72930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72930">
        <property type="protein sequence ID" value="KIC72930"/>
        <property type="gene ID" value="DB41_JZ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="16841" checksum="6FD3DD07A5617B05" modified="2015-04-01" version="1" fragment="single">MEGLIKGGTDNFAPIIEKLLNELMKIERKKCIGAESYERTEERKGYSNGFKDETLNTRSGSLKLKIPQVRGLKFYPSCLEKGCRSERALKLAIAEMYVKGVSTRRIKQITEELCGFDISATQVSRLTSLLDEELKAFRERPLERIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNZ6</accession>
    <name>A0A0C1JNZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JY00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000181">
        <property type="protein sequence ID" value="KIC72955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72955">
        <property type="protein sequence ID" value="KIC72955"/>
        <property type="gene ID" value="DB41_JY00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4850" checksum="1212154EADA1B092" modified="2015-04-01" version="1" fragment="single">EKEAKAFTKLMQQEFSCPNVTKRQLDKFVKKLKYIQIIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPC1</accession>
    <name>A0A0C1JPC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JT00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000176">
        <property type="protein sequence ID" value="KIC73065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386216.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000176.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73065">
        <property type="protein sequence ID" value="KIC73065"/>
        <property type="gene ID" value="DB41_JT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="443" mass="49461" checksum="DE606200D0A87D0E" modified="2015-04-01" version="1">MNCFPLNPFNGSKFDKILPSSTEWQPSYPENQTILPANDTDLLAKKARIHRGKSTLQETTSVYFDYLGCLQLGDEEFIKAVNKVNLLAKVVCKSADSLTDKSLLKLQQHAKVLRKLQLSSAKQMTEEGISLLVEQCHSLKMLALNAGPTLEIRFAQALSSCAQLKKLDLSFIPSITDKAIQIIAQGCRGLEKLKLRDCKKISDSSLVSISQNTRQLVKLNLSGCSHITGEELGSSDHCFFPYLAKIDLSYCSSLTNLGFQAIMGQTPQLRSLKLNFCQQLAPAVLAQEIGKLSLEKLNLTACHIEDSFFKHSFFSLLSLNITSCQGFTNEAFQKLAQTAPVLEKLNVGFCTQLKGKSVKALASKLARLKHLNLSFTKINSSCFSHLAALLELESLNIRYMKENFYLYDLALLLNTSSSLKHLVIDPSLKERIKKHLKYFHLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPP6</accession>
    <name>A0A0C1JPP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KK00270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244061.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72501">
        <property type="protein sequence ID" value="KIC72501"/>
        <property type="gene ID" value="DB41_KK00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="82"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="28216" checksum="FF9C84FC66CF174F" modified="2015-04-01" version="1">MQHVKWIVFLVAVCWFTFFVGLRSNTIRSLLVLPSKESVRAGGFNHTFHSRNAFQESALAHKLLDGLRGIEIGGSAHNPFGLKTLNVDYCDELSTPFKRAEEKTAGHALKVDIVASGDNLPFKDNAFDFVINSHVIEHFFDPIKAIKEWLRVVKPGGYVYMIIPHKERTFDKNRPRTSLEEIIYRHEHLTAPEDDDHHHWSVWVTQDMLDICKHYGWEVVAVQDIDDKVGNGFTVVVRKGEEIRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPX9</accession>
    <name>A0A0C1JPX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_KI00100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386341.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72566">
        <property type="protein sequence ID" value="KIC72566"/>
        <property type="gene ID" value="DB41_KI00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1902"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021030">
        <property type="entry name" value="DUF3731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12531">
        <property type="entry name" value="DUF3731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="921" mass="103765" checksum="DB8CB5A75878859D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQL6</accession>
    <name>A0A0C1JQL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aminopeptidase PepS</fullName>
            <ecNumber evidence="10">3.4.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pepS</name>
        <name evidence="10" type="ORF">DB41_KC00010</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386267.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000184.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72811">
        <property type="protein sequence ID" value="KIC72811"/>
        <property type="gene ID" value="DB41_KC00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1849"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035097">
        <property type="entry name" value="M29_N-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00919">
        <property type="entry name" value="THERMOPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC72811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="414" mass="46554" checksum="2944943A1CB77DD1" modified="2015-04-01" version="1">MMDFKQKLYTYAQLLIEHGLNVQKGQIVNITAEICHRELTHLLCQIAYRRGAKHVNVDFIEPRLIRTRLLDSIEDDDLAYVPHYLSQKYEEFVKEGAAVLRLIGSELPDNLTDLNPQKINTLSNSNFKALKKYYTEGVSKSKVQWTVAAAATPQWGKKVFPELEEAKACEALWEQIFKICRADQPNCLELWKKHNSVLQARAKHLTKMKIRELHFTGPDTDLKVFLSPQALFVGGGSQGPGGEFEPNIPTEECFTTPDYRLTAGKVKVTRPVLVNGKIVKDLHLEFKEGKLVHFEASEGEENFARYIDNDAGSRFLGEVALVGTDSPIFQTGKIFEEILYDENAACHIAVGFAYSMCIDGGPLMSPEQLANIGCNVSTVHVDMMISDEHVDVEATTYEGKKVKLICKGQWMQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQR6</accession>
    <name>A0A0C1JQR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JH00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73540">
        <property type="protein sequence ID" value="KIC73540"/>
        <property type="gene ID" value="DB41_JH00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1743"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="204" mass="23663" checksum="B60E9EC29DAC118F" modified="2015-04-01" version="1">MSAFCRIASMKKYEDKLEKLLNMPFFTLKEAENQGIPRWSVIYLTKNGILEKLCPGVYRSSTYEPKVDFDLENLAFTAASIPEGVICLISALCYYDLTDQIMREAWIAIPNQRRSPKRPNAHIVRMRNTDLGKETLTMGEYAVHIFDRERTIVDAFRYLSKEIALKALRQYFTLADIKPDSKKLIEYANILRVNINPYILSYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSV8</accession>
    <name>A0A0C1JSV8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC2_membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_JG00060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386125.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73566">
        <property type="protein sequence ID" value="KIC73566"/>
        <property type="gene ID" value="DB41_JG00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="28"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC73566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="260" mass="30513" checksum="8DF9E54B2734391D" modified="2015-04-01" version="1">MNFSRIKGVFFRYYYNAIKGPNQLSDIFYWPLVDILLWGLTSRWIQHQNHVANLPLVLMTALIFWQVTWRGSVDISINILQEFWNRNLVNLFSTPLKICEWIIGTILLCLCKLILTVAFGAVTVYLLYTLNVFTVGWPFIPFAILLLMFGWTLGFVAASIIIYWGHQVEMLAWMIGFLFAPFSAVFYPVNILPAWAQKISWLLPSTYIFEGMRSILDEKPFPYIYLFYSLTLNAIYLTFSIFLFKWMFEKSRQKGLGRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTR2</accession>
    <name>A0A0C1JTR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IM00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000144">
        <property type="protein sequence ID" value="KIC74500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74500">
        <property type="protein sequence ID" value="KIC74500"/>
        <property type="gene ID" value="DB41_IM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="60" mass="6964" checksum="8E639ECDEEADA066" modified="2015-04-01" version="1">MHKLPPTEAIETLELKFIKDVALLKWQYEPYKLNRDVSEMSSCMILFLFVSLSSKIAICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWH2</accession>
    <name>A0A0C1JWH2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trigger factor</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">tig</name>
        <name evidence="12" type="ORF">DB41_AV00170</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386909.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71577">
        <property type="protein sequence ID" value="KIC71577"/>
        <property type="gene ID" value="DB41_AV00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2253"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00115">
        <property type="entry name" value="tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="Trigger_N" evidence="10">
        <location>
            <begin position="21"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Trigger_C" evidence="11">
        <location>
            <begin position="283"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC71577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="444" mass="51313" checksum="45E27B97D5708227" modified="2015-04-01" version="1">MSAQQNEYKNDNLHVIFSRAPGCKIKLEITVSPLATQAAYKKAIKNVNKEVTLPGFRKGKAPENFVVQNYKAPVHQEWKDLLVNTAFQEALELTQAYPFSRNTIQRPQIKEISLEEGAHLVIEYEADPRVPKVKPDELTVKKAQKEPISPAQVQEILQQIQLSHATWEDKVDHPIIEGDYVDLTIENMDENFEICKDSRFQVEKGKLGAWLYNLLIGKNVNDVVEGMSEQDSTHAETCEDPTHDHSEHANFKPTRCKITITAHQQALLPEINDELAAKAGAPTVEELKARIEKNLEKRADEYAQMEQRRQIEKQLAEKYPFDIPYSLTKEDKELQIMQALKNIRKANLSPEEREKKSEEARQQITQSIENAYRLFYLLREIADDHQIEVSQEEIIQEFMKQMLSQETAVIDESMKAEDMRERLYSFLITQKTKDFLVEQAQHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWI4</accession>
    <name>A0A0C1JWI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386926.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71587">
        <property type="protein sequence ID" value="KIC71587"/>
        <property type="gene ID" value="DB41_AV00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="10143" checksum="50DF468A1EFB4A32" modified="2015-04-01" version="1">MAKKLNIPLVCGRIAEVPFEGIPQDYPHPIESLAANRAPSEKCDPLDQQFHASESYDKADIRYAKRTKEETESGHYSLMKSRVLWRPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWK7</accession>
    <name>A0A0C1JWK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tyrosine-specific transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tyrP_5</name>
        <name evidence="9" type="ORF">DB41_AV00320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71592">
        <property type="protein sequence ID" value="KIC71592"/>
        <property type="gene ID" value="DB41_AV00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2270"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="385" mass="42492" checksum="6A841E81297787BC" modified="2015-04-01" version="1">MLALPVITGFAGFFPSIFLLALFWMYMTYTALLLLEVNLAMGSQVNIISMAKQTLGRPGEWIGWVTYLFLLYSLTTAYLAGSGPIIMDCIKLLTGYSLPVWLGAVCLLIIFSCFLHRGTRSVDYLNRLLMAGLALAYVMMVLFLAPYVDISLLKHVDPKYLLTSVAIVATSFGFHIIIPSLIHYLERNTTHVKVAIWVGGLIPFIVYLLWELLTLGIIPLKGAYGLKDGYENGFNGAYLLSIVLGNPHLALLARCFSFFAIVTSFLGVSLSLFDCLKDSLRIEKTKKGQAVLFACTFIPPLVFALSGPRIFLVALEYAGAFGVVILLGLFPPLMAWSKRYRLLWPSSYQVGGGKEGLIGAIIFSLLVILVELANQLGLIKIEMNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWV9</accession>
    <name>A0A0C1JWV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmI</name>
        <name evidence="6" type="ORF">DB41_IB00590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385743.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74926">
        <property type="protein sequence ID" value="KIC74926"/>
        <property type="gene ID" value="DB41_IB00590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7368" checksum="31F0EBFB66BF9D90" modified="2015-04-01" version="1">MPKMKTKKAVAARFKLTATGKLKRGRPGKRHILNKKTPKRKRQLSKPALVNDAHLKTYKRLMCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWW3</accession>
    <name>A0A0C1JWW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein YciF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yciF_2</name>
        <name evidence="2" type="ORF">DB41_AM00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386736.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000210.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71737">
        <property type="protein sequence ID" value="KIC71737"/>
        <property type="gene ID" value="DB41_AM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010287">
        <property type="entry name" value="DUF892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05974">
        <property type="entry name" value="DUF892"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF892" evidence="1">
        <location>
            <begin position="11"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="DUF892" evidence="1">
        <location>
            <begin position="100"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="192" mass="21999" checksum="EDF8117D42BF10AC" modified="2015-04-01" version="1">MEKNSALDLFLETGLRHLYTAERETHDNLKTLASQSSNQALKDAFSSHILETENQIRRLQQSFGMLNIDPTSSKIQGISNFADKGRELMKTLLDLNFTDRSKGMDGILNEGKELIRHFADTDSNDIALISAAHKVEHYEIACYDLICFLCEHYKQKEIVNLMKLSLEEEKRMGEKLLEIARRDIKLPLFPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWX1</accession>
    <name>A0A0C1JWX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome bo(3) ubiquinol oxidase subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Cytochrome o ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Oxidase bo(3) subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquinol oxidase polypeptide IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">cyoD</name>
        <name evidence="15" type="ORF">DB41_IB00690</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243976.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74936">
        <property type="protein sequence ID" value="KIC74936"/>
        <property type="gene ID" value="DB41_IB00690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1504"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014210">
        <property type="entry name" value="Cyt_o_ubiqinol_oxidase_su4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02847">
        <property type="entry name" value="CyoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC74936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="121" mass="13626" checksum="B08E1CA828871A53" modified="2015-04-01" version="1">MKDNLYPIKTPQASRHGSFKSYGLGFAISIVLTLAAYIIVQEHLLTGKVLVAALVSLGVMQALIQLLFFLHLKEEDKPRWNLVALIFMIAVIAILVVGSLWIMNDLDERLMSMQEMFHPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX28</accession>
    <name>A0A0C1JX28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative outer membrane protein Omp85</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">omp85</name>
        <name evidence="6" type="ORF">DB41_HJ00100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75610">
        <property type="protein sequence ID" value="KIC75610"/>
        <property type="gene ID" value="DB41_HJ00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071709">
        <property type="term" value="P:membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03303">
        <property type="entry name" value="OM_YaeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="POTRA" evidence="5">
        <location>
            <begin position="274"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="5">
        <location>
            <begin position="356"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="739" mass="85048" checksum="F2FFA3181B13530E" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX33</accession>
    <name>A0A0C1JX33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AF00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71817">
        <property type="protein sequence ID" value="KIC71817"/>
        <property type="gene ID" value="DB41_AF00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8066" checksum="1AAA0C6C9858C17A" modified="2015-04-01" version="1">MTSVANRCLHLVQTLNNEGLAQTFKIGANISLGKWSMVIEELGFMVWSLLSFMPIFSSFWSRYLYMKKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXF2</accession>
    <name>A0A0C1JXF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75750">
        <property type="protein sequence ID" value="KIC75750"/>
        <property type="gene ID" value="DB41_HG00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4833" checksum="A0B2CA0510BC7267" modified="2015-04-01" version="1">MNNHNKDKNGYGKVAFWQEAFINIFSLTCRAQEKMLDKDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXI9</accession>
    <name>A0A0C1JXI9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">prfA</name>
        <name evidence="8" type="ORF">DB41_HE00110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75795">
        <property type="protein sequence ID" value="KIC75795"/>
        <property type="gene ID" value="DB41_HE00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1146"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="7">
        <location>
            <begin position="228"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="355" mass="40550" checksum="79C6E3538654F3C9" modified="2015-04-01" version="1">MIEKKVQQLLLRLAEVEAILGHPEIFNDQKKYKELTREHSYLAEIKVTWDDLKKAEQELSDNRELLKAESDPEFSHVLQEDIQLLESKLPELQKHLETLLVPPDPNDNRPTILELRAGTGGDEAALFVGDCVRMYKMYADNKQWNYELLSCTPSDMGGFKEYVMVLSGPNVYRNLRYEGGTHRVQRVPATEAQGRVHTSAITVAVLLEPDEDSDVQIDEKDLRVDTYRSSGAGGQHVNTTDSAVRLTHMPTGLVVYCQEERSQHKNKEKALRLLKAKITEIEQQKKAQELASNRAAQVGSGDRSERIRTYNFSQNRLTDHRINLTKYNLDKIMEGDMEDITSALVAHYYKEMFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXJ7</accession>
    <name>A0A0C1JXJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HW00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243954.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75101">
        <property type="protein sequence ID" value="KIC75101"/>
        <property type="gene ID" value="DB41_HW00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1369"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="488" mass="56350" checksum="44503E9A12713C17" modified="2015-04-01" version="1">MNSIFSSPIERLPNEVLIPILEHCATPSLFSVCRRWQHLLTTEVMPSLYRGIIKLHFPSSSRYDSIPTCILNKLYQIEENLPIVKKVSSIFHQIFILATSLSPFEFKEKTEEKRTFTLSNYFSYLLNINRLLIWKEIPDGEEFLSQEKIKQLPLKEKGELFRKWIENHKKDIKYLDLNLSGLTYLPPEIGQLSQLRILYLSENQLTTLPVEISKLFKLQNLNLSSNHLNTLPTALGQLSHLKWLNLNNNKLTSLPPEITQLSCLQWLCLNSNQLTSLSIKIEQLPQLHTLYLMDNQLNTLPRSVGQLSQLQWLDLEKNDFAFLPPEIGQLSNLQDLNISNNKLTFLSSTIGQLTQLRWLRLNNNQLTFLPSAVGHLSQLYTLYLSHNQLTFLPEEIGQLSRLQELYLDNNQLTRLPISIGSLPQLQILYLNDNQLKVLPEEIGQLPQLQELYLDNNPLTLLPASISSLLPQLRNFEISENLLKCIPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXP5</accession>
    <name>A0A0C1JXP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75850">
        <property type="protein sequence ID" value="KIC75850"/>
        <property type="gene ID" value="DB41_GZ00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="8753" checksum="AFF12438099C3A36" modified="2015-04-01" version="1">MAKIAYFAEIRASWFADLIGLKVAAPSYDTLWWFLARVHPQAFKELINRWLQGLPQEMKDQLLGMDGKRLKGVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXX6</accession>
    <name>A0A0C1JXX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isoamylase 1</fullName>
            <ecNumber evidence="2">3.2.1.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">isa1</name>
        <name evidence="2" type="ORF">DB41_HS00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.68" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385436.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000129.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75311">
        <property type="protein sequence ID" value="KIC75311"/>
        <property type="gene ID" value="DB41_HS00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1335"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004133">
        <property type="term" value="F:glycogen debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019156">
        <property type="term" value="F:isoamylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02856">
        <property type="entry name" value="E_set_GDE_Isoamylase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044505">
        <property type="entry name" value="GlgX_Isoamylase_N_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="154"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="681" mass="78575" checksum="318DF9DA90904E2D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY51</accession>
    <name>A0A0C1JY51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HM00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000123">
        <property type="protein sequence ID" value="KIC75391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385339.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000123.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75391">
        <property type="protein sequence ID" value="KIC75391"/>
        <property type="gene ID" value="DB41_HM00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1275"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="199"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="522" mass="56089" checksum="8620A580D5DBD3B9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY52</accession>
    <name>A0A0C1JY52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KU00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244073.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72107">
        <property type="protein sequence ID" value="KIC72107"/>
        <property type="gene ID" value="DB41_KU00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="10830" checksum="92207D361CA07DDE" modified="2015-04-01" version="1">MFNFWLEKILIPELKARQVLIRDNATFYKLQTTHELIKKAGCEILFLPPYSSDLNPIETFWANFKKIVAANLNKFLLLLKPLITLFKVYVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYB7</accession>
    <name>A0A0C1JYB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GP00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76030">
        <property type="protein sequence ID" value="KIC76030"/>
        <property type="gene ID" value="DB41_GP00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6736" checksum="85A7C95B736930ED" modified="2015-04-01" version="1" fragment="single">MLNNDYLTKLINLEGVKFKDIYIQEDTVRVLITPINPIRLCPYCGQPTFKLVDIKPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYQ5</accession>
    <name>A0A0C1JYQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative low molecular weight protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GN00150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76105">
        <property type="protein sequence ID" value="KIC76105"/>
        <property type="gene ID" value="DB41_GN00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.976"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="163" mass="18543" checksum="A4664850A57F552E" modified="2015-04-01" version="1">MITILFVCLGNICRSPAAEGILRHLINQEVALKNVKVQSCGLGSWHVGQLPDACMRQVASKRGIYLTSPAQAFHPKFLEDFDYIFAADQEILHHLYLRAKTVKQKVKIHLLTAFSQIYHHQNIPAPFYKRETAFDEVLDMIEEACKGFIEHLKTRNKHAEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYQ9</accession>
    <name>A0A0C1JYQ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">lgt</name>
        <name evidence="3" type="ORF">DB41_GN00200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384797.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76110">
        <property type="protein sequence ID" value="KIC76110"/>
        <property type="gene ID" value="DB41_GN00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.981"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="298" mass="34110" checksum="0128D8B15BEEEC78" modified="2015-04-01" version="1">MHLLIAWLYWNPSKDIFTLPLVNRPIAWYGLFFVLGLILSYSIVLHLMRTMLLERCCPQKNSKDISPIALVLTDRLTWYVVTGIIIGARLGHVFFYDWPYYQHYPLDILKVWEGGLASHGGAVGILLALAIYRLSIRKKFPELTFLTIADMIAVPTALAGACIRVGNFFNQEILGTPSQAPWAIIFGNPADHSLPLPRHPVQLYEAFAYLIIFALLLLIWQRALVRKKSGFMTGLFLILLFSTRFFLEFFKSSQSAVIDESKMQMGQYLSLPFILSGFFLIIYTNKAYRAFTRENENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZB3</accession>
    <name>A0A0C1JZB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">trmD</name>
        <name evidence="17" type="ORF">DB41_HE00070</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385076.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75791">
        <property type="protein sequence ID" value="KIC75791"/>
        <property type="gene ID" value="DB41_HE00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1141"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="24"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="129"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KIC75791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="229" mass="25774" checksum="420656D9BDA6FFC1" modified="2015-04-01" version="1">MLIDILSLFPNYFKGPFDESIIMQARKKGLLDINLIDIRTFADNRYHKVDDRPYGGGPGMVMMPQPVLSAIHSVKKPGAKVIYMSPQGPLLKAGKCRELAQHDHLILLCGHYEGIDERILDEVDEEISIGDYVLTNGCLSAIVLVDALVRFVPGVLGHESAAAEDSFENGLLECPHYTRPESYEGKAVPEILLSGDHKKIAEWRRKKSLEKTQRVRPDLWQKLNINLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZC3</accession>
    <name>A0A0C1JZC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385105.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75806">
        <property type="protein sequence ID" value="KIC75806"/>
        <property type="gene ID" value="DB41_HE00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="10066" checksum="409F746203F498D7" modified="2015-04-01" version="1">MRTIIIALFPSIALSQGLNSKVKARTAALLFSSYETLVKAVITTHQPLHLDAMSWRHAATNEHLLVLRVGNVIAYALRPYQNGATLKALVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZF8</accession>
    <name>A0A0C1JZF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GG00080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384610.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76400">
        <property type="protein sequence ID" value="KIC76400"/>
        <property type="gene ID" value="DB41_GG00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.892"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="12"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="163" mass="18269" checksum="8F034EFACFEAEEDD" modified="2015-04-01" version="1">MSDVQVEKPSITRIAALDYGLARIGIAVSDESKTIALPFMTLGCEKKTSDTAKKLVLLLEEHQKANHYTLLELVIGLPLLMNGKRGYLADETQYFISLLKNLLSIPVVSWDERLTSVQAERTMKEGKLNRKKRAKSVDNVAAIIILQNYLDHLKLRHGGTYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZG3</accession>
    <name>A0A0C1JZG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384979.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75866">
        <property type="protein sequence ID" value="KIC75866"/>
        <property type="gene ID" value="DB41_GZ00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="9953" checksum="8460186FCEA9F6B0" modified="2015-04-01" version="1">MLNEEEVNNVFNRLKEHPSLLESIRDLLDITEGVKGIEVADDAEFALIPEVRGLGKKCLEDWAKHQVNEQEAKTREMKLRQHSKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0E7</accession>
    <name>A0A0C1K0E7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FH00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243836.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76635">
        <property type="protein sequence ID" value="KIC76635"/>
        <property type="gene ID" value="DB41_FH00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="151" mass="17103" checksum="A38D741C0AC7CC4F" modified="2015-04-01" version="1">MLFYGLSVSLVNEHATKFLSQQLEKLIYHPVFSKLLEAKNEGSYTAIFSSSPNFLVEKVALRLGVDRWGSTIYQKNEEGDFTHITQVMEGPQKAQALELLLKELQIVKANVTAYTDSYLDLPLLYAVGNPVGVNPDRRLKAMCRQNQWPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0N3</accession>
    <name>A0A0C1K0N3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GK00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76306">
        <property type="protein sequence ID" value="KIC76306"/>
        <property type="gene ID" value="DB41_GK00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6764" checksum="F027C3C67208C886" modified="2015-04-01" version="1">MHASLKALLPDSLSKIKIERLSPFSIFIALRLLCLLEEDNFLYMFFGLVTYFLLLKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K113</accession>
    <name>A0A0C1K113_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EH00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76835">
        <property type="protein sequence ID" value="KIC76835"/>
        <property type="gene ID" value="DB41_EH00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7887" checksum="9CEAE10CC947012E" modified="2015-04-01" version="1" fragment="single">MGQKTNPIGFRLIRNKKWRSKWYANKQEFGTLLVEDKKIREYLMKKPQCQGTSQIKIRRMSEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K190</accession>
    <name>A0A0C1K190_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Shikimate kinase</fullName>
            <shortName evidence="10">SK</shortName>
            <ecNumber evidence="3 10">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">aroK</name>
        <name evidence="11" type="ORF">DB41_FU00060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="3 10"/>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384336.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76521">
        <property type="protein sequence ID" value="KIC76521"/>
        <property type="gene ID" value="DB41_FU00060"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="175" mass="19907" checksum="99B51AA39B436F5E" modified="2015-04-01" version="1">MNIILAGPPLTGKTTLGKQVACKFGWPFIDTDRLVEKCYKNEKNIQASCREIFKKEGESQFRVYEHQAILSLQGYTHSVISLGGGALEKLDNVRILKKTGQIIYIKTSLALLEKRLLDHSLPSYLENEEKPLEAFQKLVRRRSPFYELYADQIIETGSLSPSQIVAIIYESYHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1A0</accession>
    <name>A0A0C1K1A0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine/putrescine transport system permease protein PotC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">potC</name>
        <name evidence="6" type="ORF">DB41_FU00110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384343.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76526">
        <property type="protein sequence ID" value="KIC76526"/>
        <property type="gene ID" value="DB41_FU00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.770"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="60"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="254" mass="28758" checksum="81777B193178EC63" modified="2015-04-01" version="1">MKKSRFPFIITIIVLIFLYLPIIVLFINSFNDSRFGGEWAGFTWKWYERLLRERALWQSFRNSLIVALSATFASSILGTTAALALYRYKTRFQKAHYGLVYVPLVIPDILTGMSLLLLFMALNIKLGLFTVFITHTTFCLSYVTMVILARLQNFDFSIIEAAQDLGASSWTVFRKVLIPLLAPGIAAGAMLAFTLSIDDFVITFFVVGQGTTTLPIYIYSMIKYGSTPVINALSVILLIFTFIIIWLTQHLSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1A1</accession>
    <name>A0A0C1K1A1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DW00070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383683.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76895">
        <property type="protein sequence ID" value="KIC76895"/>
        <property type="gene ID" value="DB41_DW00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="380"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="455" mass="51092" checksum="A9016A0CEFDCEE02" modified="2015-04-01" version="1">MTQEVINNALQALYLGDEQPSLKRKESPGNMQGRRVATICFGSLAIIASTAAAVAAFIFASPMIAGACATTALTGTFISTILASSLKVPFSLINLVKRLTEKVKTLFQANNALNQQIEELRNQPINHEDEVAKQKIAQLNQQIEALKVEIRTSYEETHHSKETLQHARETIAKAEEQIGELTQQINELNARMGIKIEETQALQQQLEETKKIVADKENEIQEVKNSSNSESNIKVAHTALNELHTTQIAKAEIEKKLSETQKEIEKMKKKLTKVDYEKRAVEVRLKETRSKLDIAQDSLVKKEQEIGLLRKNLDNTMELSKHQVEEIKDLKARQERLEKRLSESPSSDENVPSTLTSSASAAEHLSADTSIENPVHAAKIEKLTEELQALKAAIQDKEREAEEIRSKAKAYVHEVKEGTKDFIDKLRNKIYSLMERNSSKEEILVAIDKMVNAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K222</accession>
    <name>A0A0C1K222_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DH00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77070">
        <property type="protein sequence ID" value="KIC77070"/>
        <property type="gene ID" value="DB41_DH00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="5033" checksum="E7E97880EB849D77" modified="2015-04-01" version="1">MLPFQQALDNIEQSNQVKFLVHYISQFYHVTKQDAAAYFERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K249</accession>
    <name>A0A0C1K249_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DC00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77090">
        <property type="protein sequence ID" value="KIC77090"/>
        <property type="gene ID" value="DB41_DC00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7512" checksum="A2BC0D9FCA4A0745" modified="2015-04-01" version="1">MALYFFYCFSKEWFLIGFQPIVSTIQSQIVYKNHLIAKNGDESVDIFFNHFGLLALSLFGEKHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K280</accession>
    <name>A0A0C1K280_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_EJ00110</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383860.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76781">
        <property type="protein sequence ID" value="KIC76781"/>
        <property type="gene ID" value="DB41_EJ00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.526"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038236">
        <property type="entry name" value="GlpG_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="235"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="392" mass="45078" checksum="54930A6E5E7398C8" modified="2015-04-01" version="1">MRLIGTFKNQKQAQDLSAFLECYGIKHQLEIEKNTDWGSQNYGDMIYKLWVIEEEDLEKALEKVQVFVNNPQAAMAVAPASKSWLKEPLKEKIKEAPLKMIRQKKLQYAKTNGWGTITTTLLILCTLLLFLSTFTTPSLNHITNKLPSSVLLNSPIHKALMYDYPYAYTIMDKIISAYGIESLQDPTEMTFQEQILLNTFNHTPYWKGLYAKLSNRFFTGKAFGESNPPLFEKIREGQIWRLLTPILLHDDIFHLFFNMIWLLVLGKQMEERLRPSRYILFILLAGIFTNTLQYLMGGPNFLGFSGVLCAMLTFVWRRQKKAAWEGYQLQTSTFTFIMVFIIAMFGIQLVSFLMEIYTKSPFSPGIANTAHLSGAIVGLLLGSLDFFAYKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2F3</accession>
    <name>A0A0C1K2F3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Na(+)-translocating NADH-quinone reductase subunit D</fullName>
            <ecNumber evidence="15">1.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">nqrD</name>
        <name evidence="15" type="ORF">DB41_CT00020</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="15"/>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77185">
        <property type="protein sequence ID" value="KIC77185"/>
        <property type="gene ID" value="DB41_CT00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.116"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011292">
        <property type="entry name" value="NqrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30586:SF1">
        <property type="entry name" value="PTHR30586:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01939">
        <property type="entry name" value="nqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0915">Sodium</keyword>
    <keyword evidence="13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC77185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="226" mass="24698" checksum="570ECA4E361FA85C" modified="2015-04-01" version="1">MKKKRCLLLKEEDRMVSTNVSARSYLTSQLWGGNQILVAVLGICSALGVTNRLSVSLTMGLSVAFVTAFSSLFVSLLRKVTPDSVRMITQLAIISVFVIIIDQFLQAYFFSISKVLSVFVGLIITNCIVMGRTEGMAKNVGPLCAFMDGLGAGLGYAWVLMVVGGIRELFGFGQLFGYQIIPYSWYATATHPNGYDNFALMVSPPAAFFIIGGMIWVFNTLNRNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2L5</accession>
    <name>A0A0C1K2L5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="4">BPG-dependent PGAM</shortName>
            <shortName evidence="4">PGAM</shortName>
            <shortName evidence="4">Phosphoglyceromutase</shortName>
            <shortName evidence="4">dPGM</shortName>
            <ecNumber evidence="4">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">gpmA</name>
        <name evidence="5" type="ORF">DB41_DS00120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383624.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76931">
        <property type="protein sequence ID" value="KIC76931"/>
        <property type="gene ID" value="DB41_DS00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.385"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="28"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="119"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="4">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="231" mass="26265" checksum="3D2E9D6CA8C1AA3D" modified="2015-04-01" version="1">MNVGYLRVGKLILMRHGQSCWNELNLFTGWVNVPLSSRGMQEAVEGGKLISQLPIDAIFVSSLMRAQQTAMLAMLQHSSGKVPAIQPSSQEHLEEWFQIHSEETRKKIVPVYCAWQLNERMYGELQGLNKTETVKKYGKEQVQIWRRSFEVAPPGGESLEMTSARAVPYFKNYILPALKNGMNIFIAAHGNSLRAIIMFLSHLSKEEVVQLELTTGTPIIYDYQDPHFIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2N2</accession>
    <name>A0A0C1K2N2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CN00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000004">
        <property type="protein sequence ID" value="KIC77270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77270">
        <property type="protein sequence ID" value="KIC77270"/>
        <property type="gene ID" value="DB41_CN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="38060" checksum="64EC31A1EA50CCB5" modified="2015-04-01" version="1" fragment="single">TQGNKMHPISLASIESLPNELLLPILEACVVPSLFSVCKRWHHLLGSEVMPSLYKKIAQLHFPKGNAGTQRTLMLAKVYQLEPGLTSTEKVYQVFKQVFTLAKSISPLEFKEKIEEKRGLTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEKKGGLLRDWIEENCKNITVLALSNAGLTYLPPEIGQLSQLQKLFLTQNQLTALPTEIGQLSQLQVLNLNQNQLIVLPAEIRQLSQLQVLYLNQNQLIVLPAEIGQLSQLTRLFLNQNQLTALPTEIGQLSQLQVLYLNQNQLTALPVEIGQLSQLLQLSLNQNQLTSLPAEIGQLSRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2N5</accession>
    <name>A0A0C1K2N5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DP00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76966">
        <property type="protein sequence ID" value="KIC76966"/>
        <property type="gene ID" value="DB41_DP00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.351"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="104"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="377" mass="42117" checksum="CAF0240AE291A07A" modified="2015-04-01" version="1">MQNISFEIDPWGSILALVLLSLCYGLARKKEHMRKSSLLFSHLHPSFLNAGWKTTFSQLPLWLHGGGLILFLVALTDPHLFVRRPPLAVAEKGDKNFLPTEGIAIYLLLDQSGSMAEEVTATLDSKRQNISKEALLKQVTKEFIQGNPSAGLKGRANDLIGLITFARVPHILSPLTLDHQQILKALAHIQVVKKQEDNGTAMGYAIYKTVSMIAATKYYANHLAQKNQPAYNIKNSIIILVTDGLQDPNILDKNSLWRNLGLKEAAVFAKEKGVRLYFINIDPRIYADQLSSQRRQMEEITQLTGGRLFILNDPGEMKTVYATIDRLEKSILLSQEFAGGKPPIYQQISFSPYLIAGGMLMVWLAIVLQTTLLRKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Q1</accession>
    <name>A0A0C1K2Q1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JE00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000162">
        <property type="protein sequence ID" value="KIC73602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73602">
        <property type="protein sequence ID" value="KIC73602"/>
        <property type="gene ID" value="DB41_JE00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4851" checksum="7CE642B602233E55" modified="2015-04-01" version="1">MEAYWEIWRIEDLSKKEEKNVGGKKRRAAAAIVDSQSVKITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Q6</accession>
    <name>A0A0C1K2Q6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="2">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pcm2</name>
        <name evidence="2" type="synonym">pcm</name>
        <name evidence="3" type="ORF">DB41_CJ00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383031.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77300">
        <property type="protein sequence ID" value="KIC77300"/>
        <property type="gene ID" value="DB41_CJ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.10"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="218" mass="24053" checksum="48093CD19A539816" modified="2015-04-01" version="1">MPLDDDYSHKRQEMVRTQLLARGITDLATLEAMRHVPRHLFVPASMQEDAYEDRPLPIGEGQTISQPFIVALMNQLAEIIPSSIVLDIGTGSGYAAAVAAYTAQEVYTVEFLPSLAYAAQQCFKQQAYHSIHCKVADGSLGWPEHAPYDAIIVAAGAPAIPQTLIKQLKIGGRLIIPVGDSFSQLLLRLRKTSEETYTQETFEPVRFVPLIGKEGWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K368</accession>
    <name>A0A0C1K368_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.51</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">plsC</name>
        <name evidence="2" type="ORF">DB41_CV00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383264.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77176">
        <property type="protein sequence ID" value="KIC77176"/>
        <property type="gene ID" value="DB41_CV00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="35"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="24200" checksum="1A19ED0DBDA36C02" modified="2015-04-01" version="1">MKFFYRSIYICTKKFFSLLFRHQVYGKHHLPAGPCILAPNHASFLDPPLVAISCDEEVNFLARGSLFNNTIFKKLISHLNSYPVGGISQDITSLKLILQLLKDSKKVVIFPEGKRTPTGHLLPIKPGIGMLISKSQCPIIPVYIHGTYEAWPKKKWIPRLEGQTACIFGKPIYWEAYKDLPKKKAQEEISNAIQKSLKMLNFWYLNGAQGEPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5V2</accession>
    <name>A0A0C1K5V2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IH00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000141">
        <property type="protein sequence ID" value="KIC74642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74642">
        <property type="protein sequence ID" value="KIC74642"/>
        <property type="gene ID" value="DB41_IH00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8446" checksum="8380E3110329617A" modified="2015-04-01" version="1">MAERTIFLDGKKLVYWIPSFGRRIKTRHQKEPFFSNKAKNQSHSFSQTKIAASLNPQNLWLLLNAWKVSPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9L7</accession>
    <name>A0A0C1K9L7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endopeptidase La</fullName>
            <ecNumber evidence="3">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lon</name>
        <name evidence="5" type="ORF">DB41_GZ00360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75872">
        <property type="protein sequence ID" value="KIC75872"/>
        <property type="gene ID" value="DB41_GZ00360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1101"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="PTHR43718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="4">
        <location>
            <begin position="337"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="530" mass="59121" checksum="AA9299076C30EC07" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBD7</accession>
    <name>A0A0C1KBD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GB00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243865.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000087.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76467">
        <property type="protein sequence ID" value="KIC76467"/>
        <property type="gene ID" value="DB41_GB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="8"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="129" mass="14931" checksum="54FBB06FF5E37C98" modified="2015-04-01" version="1">MVAPFCYTSTCNCLLFNFWLEKTLIPELKAGQVLIRDKATFHKLRTTHEPIKKAGCEILFLSPYSPDLNPIETFWANFKKIVASNFSKFLLLLKPLIIRFQATSYVIPYFIKFLSLSREVTFRGLGMQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBF5</accession>
    <name>A0A0C1KBF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UPF0382 membrane protein YwdK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ywdK</name>
        <name evidence="7" type="ORF">DB41_GA00060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0382 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76482">
        <property type="protein sequence ID" value="KIC76482"/>
        <property type="gene ID" value="DB41_GA00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.808"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="PTHR43461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="107" mass="11600" checksum="8A5535E533A3D5FB" modified="2015-04-01" version="1">MTAVILGAFGAHALKQKISKERLVTFEVGVRYQMYHALGLILLALAPQHLSGILLETAGWLFTAGIIVFSGSLYYVALSGNAFAGRITPLGGLLWIIAWLFVCYAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBZ7</accession>
    <name>A0A0C1KBZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FH00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76622">
        <property type="protein sequence ID" value="KIC76622"/>
        <property type="gene ID" value="DB41_FH00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6583" checksum="001CF310F0C7C90D" modified="2015-04-01" version="1">MTKHSLTSLKLKKFNEKQDCKRFMPRNKSFILNSICLKIMQKNYNSCFFKFIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCT6</accession>
    <name>A0A0C1KCT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DZ00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243793.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76882">
        <property type="protein sequence ID" value="KIC76882"/>
        <property type="gene ID" value="DB41_DZ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002148245" evidence="1">
        <location>
            <begin position="18"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="332" mass="37470" checksum="1425D34DDDA4128D" modified="2015-04-01" version="1">MCSKYVSLLGLSWVAIALSGCHQVEKSSFSPDVVNETYVHRYGVPVSPKDWSDSGHHGQILSSLANGVVVTKTYNSGVLDGDTTYSYPHSSAIEKVETYANGVLQKTSIFYLSGAPQEEIFYHTPQNRTVLTWYESGDPKSKEEFQGNLLFQGSYYGPDNQLESQVVNYHGKRIRRDNYGLLVSVDTIEKGQQTLRTTYHQNGTPKEVIPYVNGRIHGQLRTYMPAGEPCTKEEWNNGVQSGITIEYANGEKIAEVPYAEGRKHGVERRYRDGKTVVQETNWVKGQKHGPCTSYIGNTTKTDWYWQDKQVTKSHYEILNGQGSKKAIWRNVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD64</accession>
    <name>A0A0C1KD64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DO00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000031">
        <property type="protein sequence ID" value="KIC76977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76977">
        <property type="protein sequence ID" value="KIC76977"/>
        <property type="gene ID" value="DB41_DO00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="11382" checksum="E0A90CDE16FCAAF3" modified="2015-04-01" version="1">MLNYKVEEFAKAGHIQLLTDLKAVNPANSYGHRHDVFGSRTARRVSLKDLTFNMESSTLDDHPGRSNEVMIRDYIAPHFIKKLLRKPKKLKKILSISFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE76</accession>
    <name>A0A0C1KE76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CL00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000003">
        <property type="protein sequence ID" value="KIC77272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77272">
        <property type="protein sequence ID" value="KIC77272"/>
        <property type="gene ID" value="DB41_CL00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="19320" checksum="48B388C45988166E" modified="2015-04-01" version="1" fragment="single">MHPISSTSIESLPNELLLPILEACAVPSLFSVCKRWHHLLASEVMPSLYKKIAKLHFPRKNATTQRTLMLAKVYQLNPRLTSTEKVYQVFREVFTLAKSISPLEFKEKTEEKRGLTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEKKGELLRDWIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE90</accession>
    <name>A0A0C1KE90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CK00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383064.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77287">
        <property type="protein sequence ID" value="KIC77287"/>
        <property type="gene ID" value="DB41_CK00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.29"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="78"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="295" mass="33648" checksum="6333EC3639216BF6" modified="2015-04-01" version="1">MVEFNVALYKKIHRLQIQTTQLANDLLAGAYRSAFKGQGMEFEEVREYQAEDDVRSIDWNVTARMNRPFVKSFREERELTVMLLVDISASTRYGSTSSFKSDLIAEISALLAFSAIKNNDKIGLILFSNGVEKYLPPAKGTRHVLRLIREILAFKPTEHETDLAAALAYLGKIQRRPAVCFLLTDFICSKPYAHELALAAKRHDLIALALIDAYEISFPHFGLIHLTDLETGASFTIDSSSELFQRQFAYQAKARVESYRALLIKNGVGLVELYTDQPYAPLLRKFFRMRARKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H0B8</accession>
    <name>A0A0C1H0B8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BW00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000243">
        <property type="protein sequence ID" value="KIC71209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71209">
        <property type="protein sequence ID" value="KIC71209"/>
        <property type="gene ID" value="DB41_BW00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5211" checksum="4BFD947D3BAD748C" modified="2015-04-01" version="1" fragment="single">YLYAGRHLGSKQVSPKFILEEFAAPSFDIIFTLSTLEPIVHFRSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1L1</accession>
    <name>A0A0C1H1L1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="6">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">mnmE</name>
        <name evidence="6" type="synonym">trmE</name>
        <name evidence="9" type="ORF">DB41_AV00240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386948.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71584">
        <property type="protein sequence ID" value="KIC71584"/>
        <property type="gene ID" value="DB41_AV00240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2261"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="8">
        <location>
            <begin position="225"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="235"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="254"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="279"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="459" mass="50295" checksum="C5AC4092CD7FD023" modified="2015-04-01" version="1">MDFIHQPYVPGETIAAIATPPGEGGVAIVRISGNQAFDVAKKVFSGPVHSYKSHTAHYGQIRDLNNQPIDDVLLLVMRGRRSYTGEDTVEVQCHGGSLITRHVLEVILKAGARAARPGEFTFKAFMNGKLDLAQAEAVQSLIGARNEYALQAAESQLKGSLSAKVLGFQERLTLIAAILEAWVDFPDEGLEFTTLEEICQDLEAILIDMQSLFNTFRDGKILQEGISLCLVGCPNVGKSSLMNALLDKERAIVSHFPGTTRDIVEDEIRLNGLNLRLLDTAGIRVTDELVEQEGIRRSKEAMGQADLILLVLDATKGIEEQDHFLLKEVPAAKTIVIWNKIDLPHVSLPAIAHLPYVVPLSAKQKIGLDRLRQVIDSVIWKEGPPSKEEVLITNVRHREALQLSIQAGQNVLSGLKGNISPEFLSMDMRQCLAELGKIIGTNISEDILSAIFSTFCIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H201</accession>
    <name>A0A0C1H201_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_13</name>
        <name evidence="3" type="ORF">DB41_AQ00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71719">
        <property type="protein sequence ID" value="KIC71719"/>
        <property type="gene ID" value="DB41_AQ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2199"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="503" mass="57150" checksum="E6FCDE70EA258209" modified="2015-04-01" version="1">MIRIRIRLTCFFNFFILSLNNKNAEKVIITQENKMHPISSTSIESLPNELLLPILEACVVPSLFSVCKRWHHLLVSEVMPSLYKQIGKVHVPQGNVNEQALTVNRIYKLEEKLSEAAKVNAIFRQIFTLAKSLSTLEFKWKTEEKKGLTLANYFSYLLNINRLLLWKKLPGGEEYLNQEEIKHLPLEKKGELLRDWIEENCKNITALDLSKAGLAYLPPEIGQLSQLQELKLSQNQLASLPAEIGRLSKLQGLHLNQNQLTSLLTEIGQLSQLAWLYLEENQLTALPTEIGQLSKLIGLDLNQNQLTSLPAEIGRLSKLKELYLNQNQLSSLPAEIGQLSRLQRLELNQNQLSSLPEEIGQLFKLRTLYLNQNQLSSLPAEIGKLSELQRLELNRNQLTSLPAEIGQLSQLQYFCLNQNQLASLPAEIGQLSRLEALDLNQNQLTSLPAEIGQLSQLAWLYLSQNQLASLPAEIEQLSQLQTLELAENPLKNIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2U4</accession>
    <name>A0A0C1H2U4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386664.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71944">
        <property type="protein sequence ID" value="KIC71944"/>
        <property type="gene ID" value="DB41_AE00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="8786" checksum="A2986527227CD4E9" modified="2015-04-01" version="1">MACSEIYIYTQEAEEFGIKVEKLSFDHARMVKRGDLGKMMKNLEGLIASQLIKLIGGFGKFISLKNPKQCEKTNECLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3Z2</accession>
    <name>A0A0C1H3Z2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_KQ00190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72254">
        <property type="protein sequence ID" value="KIC72254"/>
        <property type="gene ID" value="DB41_KQ00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7303" checksum="00E4FC2831673758" modified="2015-04-01" version="1">MFKSQVRTAVRALEENLSKKDAALNHKHLSEIYSLMDKGVKKGVYKVNKANRTKARFAARAAKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6Y6</accession>
    <name>A0A0C1H6Y6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73249">
        <property type="protein sequence ID" value="KIC73249"/>
        <property type="gene ID" value="DB41_JM00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1779"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010344">
        <property type="entry name" value="YbjH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06082">
        <property type="entry name" value="YjbH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="739" mass="84519" checksum="CE6B46138A33275A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H749</accession>
    <name>A0A0C1H749_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_3</name>
        <name evidence="3" type="ORF">DB41_JK00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000167">
        <property type="protein sequence ID" value="KIC73309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244024.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000167.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73309">
        <property type="protein sequence ID" value="KIC73309"/>
        <property type="gene ID" value="DB41_JK00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1767"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="539" mass="61680" checksum="14B93C23ECF51D2D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H862</accession>
    <name>A0A0C1H862_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JG00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386128.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73569">
        <property type="protein sequence ID" value="KIC73569"/>
        <property type="gene ID" value="DB41_JG00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1739"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="9755" checksum="039944BFD26E90CD" modified="2015-04-01" version="1">MKGLLQDPARKKRINEEYQELLLSELIIALIEEDHISVRKLAKVAGLSPSIIQDIRSGKKDHLTLKSFANIISILGYSIVLEKSQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8C6</accession>
    <name>A0A0C1H8C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JE00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000162">
        <property type="protein sequence ID" value="KIC73604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73604">
        <property type="protein sequence ID" value="KIC73604"/>
        <property type="gene ID" value="DB41_JE00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5658" checksum="065E3BB4749E4486" modified="2015-04-01" version="1">MGDEVYGAYPLRAYLGHECCPYILAVLSNFLIIFFAEEGRKNDALKFIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8R8</accession>
    <name>A0A0C1H8R8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BS00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000239">
        <property type="protein sequence ID" value="KIC71273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71273">
        <property type="protein sequence ID" value="KIC71273"/>
        <property type="gene ID" value="DB41_BS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="133" mass="15158" checksum="3119A500C35F5F13" modified="2015-04-01" version="1" fragment="single">TTSSYDGKRLAVGLSIGFVLTYNVNDGAFLTESNIGGVAPVRFLILDESYFLASRFHPEFKKFNLCQHTPDTKYCGALWPWTPREYPVVDSHHIHASYDGRKLVFCDEHGWLHLWDFAHLQGKERILVAPPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9A6</accession>
    <name>A0A0C1H9A6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase, IS4 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BC00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000223">
        <property type="protein sequence ID" value="KIC71463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386971.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000223.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71463">
        <property type="protein sequence ID" value="KIC71463"/>
        <property type="gene ID" value="DB41_BC00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="558" mass="64362" checksum="E3E01E84CF7DDCDA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA69</accession>
    <name>A0A0C1HA69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AN00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000211">
        <property type="protein sequence ID" value="KIC71728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71728">
        <property type="protein sequence ID" value="KIC71728"/>
        <property type="gene ID" value="DB41_AN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4575" checksum="2A6A9A61C7396FA4" modified="2015-04-01" version="1" fragment="single">MSGPIERPHQDLAARAAFLKTFTLTFSSHLKLNIDTYNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAX7</accession>
    <name>A0A0C1HAX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71943">
        <property type="protein sequence ID" value="KIC71943"/>
        <property type="gene ID" value="DB41_AE00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4074" checksum="4F32FD6592D63924" modified="2015-04-01" version="1">MENSPNHPDGVAIEEGSACDPAAIHTTQGGKSIALINAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB68</accession>
    <name>A0A0C1HB68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72038">
        <property type="protein sequence ID" value="KIC72038"/>
        <property type="gene ID" value="DB41_AA00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="161" mass="18655" checksum="F718D05239DE613C" modified="2015-04-01" version="1">MYVKNLIGFENLLLSRKSNREFPFNFNTKEEYMASKLQSFSESADLPVDYEGTLTSSLNIPLDEVVLRHFGSDSIICMTLLSGRTIELPLHLNLKESGQAMLAIPEKYYKQSEHCRELEHLLSHLFNNQRSLLMEIDAQAQQLIITPLQSKKNKFKFTFYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBT4</accession>
    <name>A0A0C1HBT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74884">
        <property type="protein sequence ID" value="KIC74884"/>
        <property type="gene ID" value="DB41_IB00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="16910" checksum="EAFC78779B135196" modified="2015-04-01" version="1">MAIRTMGTCLKKPLRKLKHNSGKNIEIAFVDKGYRGHTVEGKTIFISGQRKGLNYWIKTQIKRRQAIEPHIGHMKNDGKLGRNYLKSRLGDCFKPILCGIGHNMRLIYNWLVAQNFPKRLYSGYKSSFSLLIALKPYLEGYPLLQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBV4</accession>
    <name>A0A0C1HBV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385719.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74904">
        <property type="protein sequence ID" value="KIC74904"/>
        <property type="gene ID" value="DB41_IB00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036502">
        <property type="entry name" value="NiSOD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014123">
        <property type="entry name" value="Superoxide_dismutase_Ni-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09055">
        <property type="entry name" value="Sod_Ni"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002146530" evidence="2">
        <location>
            <begin position="23"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="198" mass="23289" checksum="A3D24A96C054EB4B" modified="2015-04-01" version="1">MKKTILVQGIIVLLCHTGSLMAHCQMPCGIYHDELVFNQIDQYIETMYKGITELNNSKFSTPFERNNFIRWVKLKDSASDEIANLITEYFLQQKIKPAEADTPKRLISAHKMLFELTAIKQNVNIKMIEAFADEWENFKQMFHVINYECQIDLIKRRKRERDFQLKDQRELNDKHSSAGNPPSDKQHEHSSAEHEHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC30</accession>
    <name>A0A0C1HC30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB01020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385798.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74969">
        <property type="protein sequence ID" value="KIC74969"/>
        <property type="gene ID" value="DB41_IB01020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="170" mass="19706" checksum="9443781403B28F02" modified="2015-04-01" version="1">MNQFFYPLLTFVISLFFVVLGLLSILVQASPHVRAEFVAFIEKDQLFLSLFGIGCLAIGVAIIFYLRTNLKKSYLKINSKDNHAYFLDENIFQEYMHDYWKQLFPKEEVPNSILIKKNKIVITADLPYIPSAKQKALLARINDDVKKMLARLLGYQQEYVLALSFQKETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCN5</accession>
    <name>A0A0C1HCN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribosomal protein L11 methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">prmA</name>
        <name evidence="1" type="ORF">DB41_KI00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244047.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72563">
        <property type="protein sequence ID" value="KIC72563"/>
        <property type="gene ID" value="DB41_KI00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="279" mass="31457" checksum="BBB48E145BFB9685" modified="2015-04-01" version="1">MDDIKPFSCFALHVKNETPLDEAWESLQEAGLNPLYMEEDFKAFPRIYILAENELTVKSLLNLFPFIQFAELSELGEIDWQSQWEAHGLNFYDGCVHIDLPYACSSYGKQLKLMPGAGFGDLSHPTTRLIVDMLNDNVWGKEVVDIGCGSGVLALCSVALGAKHVYALDIDPEALKHSRENALLNKMQDKVTISLPQDFIISSLSAPPVILMNMIMAEQQNAWEALKCLHGHHDICLVSGILSEQKQDYLHLAQAWGWKVLKEQEEQGWVSLQFEIRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD06</accession>
    <name>A0A0C1HD06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Octanoyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.181</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lipB</name>
        <name evidence="2" type="ORF">DB41_HS00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385429.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000129.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75304">
        <property type="protein sequence ID" value="KIC75304"/>
        <property type="gene ID" value="DB41_HS00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1329"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="50"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="268" mass="30231" checksum="418821C22A17759F" modified="2015-04-01" version="1">MKIAGKFLFFGTGSSLGVPVIGCECAVCRSESPYNKRLRSSGLIKIHDKQIVIDCGPDFRTQMLHHHIKQIDGLILTHAHYDHTGGFDELRILNARSKQPIPCLLAEATAEELKMRFPYAFDKTSSTEKLTTRSVLHYLKSERGKVNFLGLPIHYVTYQQGGMLVNGFKVGNFAYISDIRHYPQTIFEDLQGVETLVVSCLRQQSSPLHFNVQEAIDFASKVGADQAWFTHIAHELEHDYTNSKLPPNYQLAYDGLEIDFEIPLTSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD48</accession>
    <name>A0A0C1HD48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HQ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000127">
        <property type="protein sequence ID" value="KIC75339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75339">
        <property type="protein sequence ID" value="KIC75339"/>
        <property type="gene ID" value="DB41_HQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6659" checksum="BF97963ED26EE930" modified="2015-04-01" version="1" fragment="single">EAWRDPIPYIDVGGLIRSKRDTVTLNSCPGAAFHGHSFQSPTYEEAIDDHISTFLKNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDX0</accession>
    <name>A0A0C1HDX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JY00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000181">
        <property type="protein sequence ID" value="KIC72953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244036.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000181.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72953">
        <property type="protein sequence ID" value="KIC72953"/>
        <property type="gene ID" value="DB41_JY00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1839"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="526" mass="59922" checksum="83FD685D737D8E19" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDY2</accession>
    <name>A0A0C1HDY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HJ00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75604">
        <property type="protein sequence ID" value="KIC75604"/>
        <property type="gene ID" value="DB41_HJ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7613" checksum="D74FF3AF2E151D8D" modified="2015-04-01" version="1">MPLFLSILSIFQSKAQAFKLERGKPFFKPQTSGHIFRNEACIKSDIMDTAFLEDDQRTSFSLINKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEM4</accession>
    <name>A0A0C1HEM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JQ00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386196.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73158">
        <property type="protein sequence ID" value="KIC73158"/>
        <property type="gene ID" value="DB41_JQ00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036679">
        <property type="entry name" value="FlgN-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140566">
        <property type="entry name" value="SSF140566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15609" checksum="3A26B577E99C27C9" modified="2015-04-01" version="1">MAKNFSSLCSLSNDEALYHLLKKEHDYYKDILTLTHYEHEKLISKHPPQEMHSLLSKKKALVACIRDIEKTLTPLKKYWINKSSHDPSSLQINELLTSLCDILKEILQLDLVNQKLLKNLLSQLPQVEMDNKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGX9</accession>
    <name>A0A0C1HGX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384264.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76569">
        <property type="protein sequence ID" value="KIC76569"/>
        <property type="gene ID" value="DB41_FM00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="183" mass="21146" checksum="65B14F40AAA82A46" modified="2015-04-01" version="1">MNKIYMPIFIILMFILSGCALSLLNSYEEPKQAKFVSEILDKASKKLRSKYDMRTIGTGIGMPDGVVTMLALSFEKTGPLSREEGRRIIVDCVQEMLQIINTHERIRPYLKNYPFTPNDIEIAIFLNGPSAHPIYYPDFDVISSTNEQINYMFTASENPKRYMKVEKEKFEEALKMVQNENKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH61</accession>
    <name>A0A0C1HH61_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">D-alanine--D-alanine ligase</fullName>
                <ecNumber evidence="14">6.3.2.4</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="14">D-Ala-D-Ala ligase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="14">D-alanylalanine synthetase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="13">UDP-N-acetylmuramate--L-alanine ligase</fullName>
                <ecNumber evidence="13">6.3.2.8</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="14 17" type="primary">ddl</name>
        <name evidence="13 17" type="synonym">murC</name>
        <name evidence="17" type="ORF">DB41_FH00050</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="14"/>
    <dbReference type="EC" id="6.3.2.8" evidence="13"/>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384117.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76624">
        <property type="protein sequence ID" value="KIC76624"/>
        <property type="gene ID" value="DB41_FH00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.659"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 13" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="586"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="112"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KIC76624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="808" mass="89837" checksum="B3C34A3210B92AFD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHN7</accession>
    <name>A0A0C1HHN7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplC</name>
        <name evidence="7" type="ORF">DB41_EH00130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383790.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76829">
        <property type="protein sequence ID" value="KIC76829"/>
        <property type="gene ID" value="DB41_EH00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.478"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="223" mass="24120" checksum="C9C94251A8E83AEC" modified="2015-04-01" version="1">MAPKLMGKKRGMIQLFDENGNSIVGTVIEVQPNAVVQIKKKEIDGYNAIQIGFDKIHVKDQRTLANRLSKPLRGHYSKAAVSPRKNLSEAKVDNIEQYQVGQELAIDLFAEVKFVDATAVSKGKGYQGTMKKYNYSGGPASHGSGFHRHAGSTGMRSTPGRSLPNSPRPSHMGCETVTIQNLEVVMVKPAEQVIIVKGAVPGPTHGLVYIAPSVKKTSLKKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI04</accession>
    <name>A0A0C1HI04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1,4-dihydroxy-2-naphthoyl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IR00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.28" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386046.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74233">
        <property type="protein sequence ID" value="KIC74233"/>
        <property type="gene ID" value="DB41_IR00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003230">
        <property type="entry name" value="YbgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="16208" checksum="4AAD76DD03165EE9" modified="2015-04-01" version="1">MFISYNKVRMHDTDMAGILYFAKQFRFVHDALEDLMDQEGITLDHLFHHSSFAFVVVHAEADYLKPVKVGDALEVHVEVIHLGTTSFSFAYKIFRKVDHLLIGKAKTVHVCLDTQTRSKITLPDELKNIFKKYQPIQQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI39</accession>
    <name>A0A0C1HI39_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">valS</name>
        <name evidence="13" type="ORF">DB41_DO00030</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000031">
        <property type="protein sequence ID" value="KIC76979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243782.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76979">
        <property type="protein sequence ID" value="KIC76979"/>
        <property type="gene ID" value="DB41_DO00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.333"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="24"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="568"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="658"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="892"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="887"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="569"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="954" mass="110504" checksum="870D48B52336A545" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI91</accession>
    <name>A0A0C1HI91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383514.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77004">
        <property type="protein sequence ID" value="KIC77004"/>
        <property type="gene ID" value="DB41_DN00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="25184" checksum="1183AB9688AF0B68" modified="2015-04-01" version="1">MAITSSVTSSFILPIKTCPQKTAHASQLFADMRKRCSYLLARIKEIALGIFYYFQEFFKDLKDDLSIWWFEKEDPLDTEARIECERLRPEIEELKRKTFLLDTFINERPELKNKCLEYYHKYKHFFIKNQRGSPRTRLAIDLDLNNPVDQLNILEVEKIDLEYELDQRIDFITSFKEVHALFEKHVLEAEKAAKGAGNVFPLLLTQALENKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIX1</accession>
    <name>A0A0C1HIX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CR00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383195.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77214">
        <property type="protein sequence ID" value="KIC77214"/>
        <property type="gene ID" value="DB41_CR00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.100"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="209" mass="23970" checksum="8535BB73013DB5A2" modified="2015-04-01" version="1">MFEEESFSLSPVNFFQLKGDCHYAPKGISGQKYLLADTSYLCGEEHFSKVSLGWNEQGLECLVAVSQPFKQAYHPDVSRGDSVELMIDTRDVKTSGFNTRFCHHFFFLPEAVDGIQAGEMTRFRTEDKHELCDANELKVNSQLSSQSYTLKIFIPSHCLVGYDPEQFDRLGFTYRVNRKNESPQHFSVVTRDFQIEQQPSLWSSLSLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMY0</accession>
    <name>A0A0C1HMY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HH00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75708">
        <property type="protein sequence ID" value="KIC75708"/>
        <property type="gene ID" value="DB41_HH00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1198"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="146" mass="16465" checksum="43F7BD80B85E6F9A" modified="2015-04-01" version="1" fragment="single">EIGQLSKLQWFNLSQNQLTSLPAGIGQLSQLRGLDLNQNQFTALPAEIGQLSDLQRLELNQNQLTALPAEIGQLSQLRVLYLNQNQLTSLPIEIGQLSNLLQLYLNQNQLTSLPIEIGQLSDLQRLELAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN95</accession>
    <name>A0A0C1HN95_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_HE00140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243926.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75798">
        <property type="protein sequence ID" value="KIC75798"/>
        <property type="gene ID" value="DB41_HE00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="7">
        <location>
            <begin position="38"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="283" mass="32048" checksum="5CFC08193B2AEF41" modified="2015-04-01" version="1">MTAIVTICSAALEPLFIAIFKIYGPQEILGLSPWGIANSYYWQLITSLFIQKHANGINSFLLINLTFNMYILWLFGSQLAEYYGDKSFLVLYFMSGILANLAALAAVSLLSPYKMFIIAGLTPSLLAIFVAWAMLHRETTLLLFFLIPIQAKSLLAVVIAFSLLIPLSALDFVNLFYHMVGIASGYLYSVVVWQQPTPYLYMQNIDKIFMGWGHHLHTKIRRYFFSTPQKSKIVDIKTGKATLGDDAFIDEMLAKISRSGEQSLTRQEKDRLRKISEEKMKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNL8</accession>
    <name>A0A0C1HNL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative soluble pyridine nucleotide transhydrogenase</fullName>
            <ecNumber evidence="5">1.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sthA</name>
        <name evidence="5" type="ORF">DB41_GZ00570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385018.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75893">
        <property type="protein sequence ID" value="KIC75893"/>
        <property type="gene ID" value="DB41_GZ00570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1124"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003957">
        <property type="term" value="F:NAD(P)+ transhydrogenase (B-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="7"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="3">
        <location>
            <begin position="345"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="471" mass="52223" checksum="B36EF2CEA8359EE7" modified="2015-04-01" version="1">MEEMTVDLVVIGAGPAGQKAAIQGAKLGKKVIVIDKLPEPGGNCLYSGTIPSKSLREAIIDLTRFYERGFNSGEFALQEVSIPQLNQRLHKVIEEERSTVYRQLRKNGIRLIYGTARFENPRMLIVMDDDYRLLHQINTEFVVIATGSKPRNPNNIPFDNDVIFDSTRLLGIEKVPSSLIVLGGGIIGSEYASFFAALGTEVTVIDKKDHILPSLDPEIGIILQTSLKDLGLRFLGNKEAAQIARINDKAYVKCKDGTEISADALLFALGRSAYVDGLHIENAGLSVNNKGYIPVNALFQTERPNIYAVGDVIGGPCLASTSMEQGRLAARHAFGVHHRLFPNLYPIGIYTIPEISSCGYNEDELREMGFRYEVGRAYYYEIARSHIVGSNTGMFKILFHAETLEILGVHIIGRSATEVIHIGQVAMSFNAKIDYFIDQVFNYPTYAEGYRIAALNGFNKISYKKYVDVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNR6</accession>
    <name>A0A0C1HNR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GW00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384928.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75938">
        <property type="protein sequence ID" value="KIC75938"/>
        <property type="gene ID" value="DB41_GW00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="511" mass="59052" checksum="4D2BBD769C8321FC" modified="2015-04-01" version="1">MNIFTIATVEDHYSISHLHFPPLSSKTHRFSQKLMSFYLKSRSLNLIALGSITCSVATSLLALAETVAALAYTVFLTSLNFLSFCRSELLQNHTVQAWGFCIQSFLMVQSPWLLISQLNHLSKYDRIRHEHFHKIKSAQIAQSLRVAFDFIGEDFKMSEDFSPSEAYGFAVAVEAMPDLINEAKKYMPILRDADQNEFDPQKLADIDRFEFIEFLEDKKGLINSLQHLKLLANIPEDKNEQKELLELITLQLCKHQQYASLLLANPIAKLGQMQGLTSHLPTRLKEREIFFKLKSFEKASYSPAYQMQPLEDANDEIYQIFNFNEIPLPSTEKSETAYEKNLEIYIKYSIKYVMSSERYINIFGVEQEDSYSKKEAVKACIQDLEAVIQINLLAILLELITLQKCRYKCPSPGRQQIIELALIAYESIKDNNKAKNLLIRMILQDKEFEIEKDSFIDKYTGIKYEIDSTTRQQVQKVFRYITVLADHLQYRKDLNKVTLKALEEVEGCSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ15</accession>
    <name>A0A0C1HQ15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76293">
        <property type="protein sequence ID" value="KIC76293"/>
        <property type="gene ID" value="DB41_GK00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5677" checksum="3D0C028E04E07DF3" modified="2015-04-01" version="1">MLKRRLKKGIKNFVSFYKDIQAGNKESLLANAFYQLKFLLYYILFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQG2</accession>
    <name>A0A0C1HQG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GD00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384571.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000089.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76428">
        <property type="protein sequence ID" value="KIC76428"/>
        <property type="gene ID" value="DB41_GD00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7307" checksum="746F62598114266C" modified="2015-04-01" version="1">MYPSKIIDKISLVIALTALFFSFILFYRETFEARQSFAAALMLAALVWLSYIMLRCLLLALRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQT4</accession>
    <name>A0A0C1HQT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FT00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000080">
        <property type="protein sequence ID" value="KIC76533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76533">
        <property type="protein sequence ID" value="KIC76533"/>
        <property type="gene ID" value="DB41_FT00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="74" mass="8496" checksum="68DD741120DB56AC" modified="2015-04-01" version="1">MCTMLFKFLIEKLFGDKRYTWSSFLRKKKRMPMGRKEEPSAAIVDSQSVKTTRGRGLKGYDGGKKSKEGKGIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR78</accession>
    <name>A0A0C1HR78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">murG</name>
        <name evidence="13" type="ORF">DB41_FH00040</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384114.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76623">
        <property type="protein sequence ID" value="KIC76623"/>
        <property type="gene ID" value="DB41_FH00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.658"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="190"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="367" mass="40755" checksum="B3EBD0CAC63A4658" modified="2015-04-01" version="1">MGKRIIITAGGTGGHIYPAIALGKQLMVADGSLELLYVGGNLDINPYFDKDLFRYQAISCATFINKSPWETLKASYKILKGIKQSCKIINEYRPDMVAGFGSYYTLPMLLAAKAKEIPFILHEANSVPGKVNRCLAKYASFVGIHFPDTAGFLGGKTYEVGMPLRPEYYKGGSSSSKAREFFGLEKERDTILAFGGSQGALNLNNLVSEALVQHLKHAKEQWQIIHLTGDASTSQFLREEYQKAGIKACVKPFENHMELAWQAADISITRAGAGSIAEQMEFEVPGILIPYPYATDNHQEKNAAFLVEKVGGALRCQEKELNAFDLAGEIESLTLEKRKKMSQAMQNYKINHRPKEFYTLILEALHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRT9</accession>
    <name>A0A0C1HRT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-alanyl-D-alanine carboxypeptidase DacB</fullName>
            <ecNumber evidence="5">3.4.16.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dacB</name>
        <name evidence="5" type="ORF">DB41_EG00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243799.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000046.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76838">
        <property type="protein sequence ID" value="KIC76838"/>
        <property type="gene ID" value="DB41_EG00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.460"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S11" evidence="3">
        <location>
            <begin position="27"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="PBP5_C" evidence="4">
        <location>
            <begin position="347"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="399" mass="44962" checksum="E132BA3776FA50D0" modified="2015-04-01" version="1">MFLQRLCLGLLLFLGIGSLSAEKLEVSVESEAAILIDVTSGAILYEKNAHTLNYPASITKIATTLYALDQKGHQLSEIVTADTEAIASISEQAKKKSNYTTPSHWIEYASTHIGIKKDEKFTLKELLYGIMVASANDAANVVAQHVAGNIPLFMHGLNGFIKSLGCQNTYFTNPHGLHHPKHQTTPYDMALLTREAMKNSIFRELAAAPKFIRPKTNKQEPVVILQKNRLLRRGDYYYPQAIGVKTGYTSIARHTLVAAAKKDGRELLAVLMKCNEGGQIYRDAIHLFEAAFNEEQEEMIILEKGLQKYIYSLKGADRPLKTFIKSPLSFKYYPSEEPVVKCYLQWHSLKLPIVKGQQVGEVYLQVNGQQVEKVALYAEHEVQQTWMEWLKSIFKITKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRV7</accession>
    <name>A0A0C1HRV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76853">
        <property type="protein sequence ID" value="KIC76853"/>
        <property type="gene ID" value="DB41_EC00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5035" checksum="28754348E3DFC02F" modified="2015-04-01" version="1" fragment="single">TQNASLEKSPTKIARSQRNHIFVSLIAYCKLEFLKLKPFSITVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS10</accession>
    <name>A0A0C1HS10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">hrcA</name>
        <name evidence="7" type="ORF">DB41_DW00050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HrcA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76893">
        <property type="protein sequence ID" value="KIC76893"/>
        <property type="gene ID" value="DB41_DW00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.410"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HrcA" evidence="6">
        <location>
            <begin position="118"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="397" mass="45877" checksum="91875F134599936A" modified="2015-04-01" version="1">MKALKLITVKKSAKHNRERQVLMGLIELYLKTGKPIGSHTLKEFRFEELSSATIRNYFSNLEKEGYLSQQHSSGGRIPTTQAFRLYAQEHSTTLQTSEAYQHELQKLRDKETHELASYLQEAAETLSHLAECAVFLSAPRFDQDYINQIKIVEIDHTRCLCIILTSIGLIQTEIMPLDKRMSTFSLKRMERYFQWRLNRIHQSPSSIDINTPDNLTEEEKNLAQLFYNEIMVRYIVSYSNFTDEDIYRTGFSKLLAYPEMQDVSKLTHCLSLFENVPSMRLLLKECSKKETLKFWIGEDLDFLSVGPQECSVVTVPYYANKQCVGAIGLLGPIRLPYRHLFGLLHNFSENISEAITRSIYKFKITFRQPQRGTISTQPDKPCFLGESSLMLIEHNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSE8</accession>
    <name>A0A0C1HSE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383513.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77003">
        <property type="protein sequence ID" value="KIC77003"/>
        <property type="gene ID" value="DB41_DN00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="209" mass="24612" checksum="FBA155A0BB575023" modified="2015-04-01" version="1">MAITSSVTSSCILPIKTCPQKTGHASQLFADMRRRCSYLLARIKEIALGIFYYFQEFFKDLKDDLSIWWFEKEDPIDTEARIECEKLKPKIEELKRKTYLLDTFINERPELKNKCLEYYHKYKHLLIKNIRGCGRTDFDLDNPVDQLNILAVEKLDLEFELNQRINFITRFKEVHALFEKHVLEAEKATKGAGNVFPLLLTQALENKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSH0</accession>
    <name>A0A0C1HSH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YyaL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yyaL</name>
        <name evidence="2" type="ORF">DB41_DM00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000029">
        <property type="protein sequence ID" value="KIC77018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383487.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77018">
        <property type="protein sequence ID" value="KIC77018"/>
        <property type="gene ID" value="DB41_DM00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.286"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="PTHR42899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredox_DsbH" evidence="1">
        <location>
            <begin position="6"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="675" mass="77807" checksum="2A81EFEC31FE6A2A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSL3</accession>
    <name>A0A0C1HSL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Addiction module toxin, RelE/StbE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DI00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383442.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77048">
        <property type="protein sequence ID" value="KIC77048"/>
        <property type="gene ID" value="DB41_DI00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="10168" checksum="45A7B7167591B22F" modified="2015-04-01" version="1">MRYEVEISESAEKFLKKVPKKDRLRILEKIDILVDDPMPSGSIKLHGQKTPLYRIRSGDYRVVYSIKKDVLIILVVELGHRREVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJS9</accession>
    <name>A0A0C1JJS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endonuclease III</fullName>
            <ecNumber evidence="5">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">nth</name>
        <name evidence="7" type="ORF">DB41_AV00250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386923.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71585">
        <property type="protein sequence ID" value="KIC71585"/>
        <property type="gene ID" value="DB41_AV00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2262"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01083">
        <property type="entry name" value="nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="6">
        <location>
            <begin position="39"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC71585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="207" mass="23237" checksum="ED9B0139F968CE49" modified="2015-04-01" version="1">MNRKEKAAKIFAILNKLYPNPPIPLLHKDPYTLLVAVLLSAQCTDKCVNQVTPKLFAKADTPEKMAQLDIEDIQKIVRPCGLSARKAAAIHRLSEILAEKYQGKVPDTFEELEALPGIGHKSASVVLSQSFGKPAFPVDTHIYRCALRWGLSKGKTVAAVEKDLKLLFPQETWNKLHLQIIYFAREYCSARHPHVDRCPICRIITPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKW3</accession>
    <name>A0A0C1JKW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BW00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000243">
        <property type="protein sequence ID" value="KIC71206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71206">
        <property type="protein sequence ID" value="KIC71206"/>
        <property type="gene ID" value="DB41_BW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5701" checksum="B067FA0811AA71A9" modified="2015-04-01" version="1">MKNDGKLGRNYLKSRLGDCFNAILCGIGHNMRLIYNWLVAQNSPKRLYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLN6</accession>
    <name>A0A0C1JLN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copper-sensing transcriptional repressor CsoR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">csoR</name>
        <name evidence="2" type="ORF">DB41_KR00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386511.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72180">
        <property type="protein sequence ID" value="KIC72180"/>
        <property type="gene ID" value="DB41_KR00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="100" mass="11680" checksum="0862898175E566A1" modified="2015-04-01" version="1">MKNSKGEHTQAKPPSYHDQLSHLNRISGQLEGIKKMIKEERYCPEILTQLRAIRSAVKSVERRILDNHLSSCVTEACLSHNQEEQKKKIEEIRILIKRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLZ3</accession>
    <name>A0A0C1JLZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AV00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386880.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71566">
        <property type="protein sequence ID" value="KIC71566"/>
        <property type="gene ID" value="DB41_AV00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="46407" checksum="801D3BCC7A750DB9" modified="2015-04-01" version="1">MTSGNITGQSQGGGVYLPSSDSGAVPAAGANSAAKAVAQPNQAYYTDSTSTGKEAVSAKHTRNLLAHIPPPNAQAAGVSESSGTGNPFLRPNPLVAFFMNFTEISNVLRQMTMAQEEITLSQMSMINELAKGQAQQILQAAEKESKMYMASAIACFMEAGVSLGQAAMQFRVNRNVDKDMEKQKGTYKDESTRLKGHKANAKQHYDEVSGQHTANEMKVQQMRNADKNVAEAKKNLESAKQGGSREGITASEQKLKDAKDQRDIAYGEELDKDTRKGRLKEAEARSLRSSEESLSAKRDLNRANHESETANYELEKFNTSYAMTHANSVTNKMMIFNMTSTMLNKSTEGMMNLWKSELVVEKAQAEALKAMMDAYIQNSFKTVDLMNNAKSENSKLIADLMQQLRKFSEDERKLGSSVGVQSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM00</accession>
    <name>A0A0C1JM00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386893.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71571">
        <property type="protein sequence ID" value="KIC71571"/>
        <property type="gene ID" value="DB41_AV00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2247"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="442" mass="47623" checksum="816D311784BC6DF6" modified="2015-04-01" version="1">MTSSTNSQNFLEDLNSIAGSYVLDTSLSYVSGQLAVIPTQKLYNTSTTSAATLNSNLTPTNFNSVDTTDITSFINQFYTKVLGYPSTSSIPSAAYDPSNSASPLNGLYNIYTASVGANPDIGNTDLSSIIDVSNLPGQFKAAFSDFIKNFNFSILSSSSTSETLTLNGTTYTATLSNNYGNFTKAFLNYLSTTTVIQTSNKSSVLSLLNSQNSTGVTYVQSYQAIYESFNGPVGTLSQNSANWTVAQRVFVQRLSAFYTSELAKTATSSQPSGSFEASQDLGDWYSYTQNLYYNPQFSPTALTRDSNSTYILNEVLLALISMLGTIQNVAASQSQTLSFLSQWQAAYSDKLRQMRTFTQGDGTVLGGTNGWDKDAAQATRNALNNVNQNYISKLQASQQTLSDQAKSLQANVNQSNDAASQQGSVADSILQQLSTILSAIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNA9</accession>
    <name>A0A0C1JNA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AA00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386557.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72026">
        <property type="protein sequence ID" value="KIC72026"/>
        <property type="gene ID" value="DB41_AA00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002152241" evidence="1">
        <location>
            <begin position="23"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="481" mass="55329" checksum="EB6807B6BF037B05" modified="2015-04-01" version="1">MKHYKLLFSLLALMGITSIISAQEIENNRLSQEGRLNERDFNALQEYISTKRNVDLAEKANNLKVSGDVRSEWRHVNEKGVLPKTEGGKSVFSQAHYVSDGDYKKLRGGKATDPYTIKDKVTPRGLPLSRNDFNVEFNVFFKYEYDRAYAVAHLQYDNACGVSDNGWLDFSQDPAGYHGSGAGKDFSLKRAYWGYNIYEGGGTRFDIEVGRRKLYDVFESEVQFGSRMDGIALYYSGSTEAIGEWYWTVAGFVVDERVNHLAYATEIGLMNIKDYGLDVQYSFINWNKYGRNRFLVRNPNGFRFKTSQLTLTYHLNPDWFWGKPTQIFGAVLYNGEGRHRSGAYEGRRDELNPTQWYVHHHQNHHHRSDNRQKWGWYLGFLIGQVEKEGDWSFEAQYQCVQAYAMPDNDTNGIGRGNILEESITYQGRGNTNYKGWKFEGLYALTDNLSLDVKLELTRAAKKSIGGKHHYSNFVAEAIYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNB6</accession>
    <name>A0A0C1JNB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AA00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386560.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72031">
        <property type="protein sequence ID" value="KIC72031"/>
        <property type="gene ID" value="DB41_AA00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="326" mass="36836" checksum="1F070295141BD57B" modified="2015-04-01" version="1">MSSVASTSQNAYQSPMFAKDFYKEKLLYPSTNKHTITYTHKEIKPLSLLLTHDSQDDNKKMGKIIKSVASLAECIIHILIQQAEENKQTALYYQFQLAINKEISTLVTIYSLLEARKVNPRALALMHVINTLMQSLFFNEQIKNSWNTLLGNKKNTCRSSLNSSSTKQEPAASTPLKQVKASSSAATLEGPFINNEYVIYAHPKVCIDTTDLEFSDDNEKDEKKMRNIQTAVAAIAISILCFDDYQKAHAQEGKMIAKIATLLNKELAWLAVIYGLLERQENHSLLIEQKVQAMKDVVETTIASLSTIEYVNKWWKAYLEKSNSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNK1</accession>
    <name>A0A0C1JNK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KC00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386275.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000184.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72815">
        <property type="protein sequence ID" value="KIC72815"/>
        <property type="gene ID" value="DB41_KC00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="261" mass="30169" checksum="1AF3CEEA2674413C" modified="2015-04-01" version="1">MVKKHSFSPFAFSPKCQRVSLLSPQFALIILLMIALLSGIVWQIGHVNEKDELEYRKLLAASQSSKSAMQLNSYTARQEREGVQKDIYFYKRGERLHMRLIADAAQLLLKQQDSHPQVVEHLQNVKCLMQEELYYLLPDGREAVLQPDGQLRLRSAHTASLSSSWSPESRLEWRPMQLLRFIEAETAEYHYKKDLLVANKVKMKRYAIAGHQLKEVVEQEKILMQGTADKVEFSLKGEEEAFHLKAYHFKAKLFGPEGRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNX9</accession>
    <name>A0A0C1JNX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate regulon transcriptional regulatory protein PhoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phoB</name>
        <name evidence="6" type="ORF">DB41_KQ00060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386475.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72241">
        <property type="protein sequence ID" value="KIC72241"/>
        <property type="gene ID" value="DB41_KQ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2010"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="132"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="231" mass="26104" checksum="D36400E21E0C3868" modified="2015-04-01" version="1">MQKSKIVLLEDEEDIAALIKLQADISGYKLHTETDGLNGLRAIEKEKPDLVILDIMLPGLSGLDVCRKMKTHPELKDIPVIMISAKSEELDVVLGLELGADDYVAKPFSPKVLFSRVRAVLRRGKDLPEKALKTIAFGNFTMEVERYLVRKNDKSISLTLSEFGILKRLVTNMGKVLTRNQLLDDIQNSDAFVVDRNIDVHIASLRKKLGPNFQWIETVRGVGYRFLEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPL3</accession>
    <name>A0A0C1JPL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386379.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72476">
        <property type="protein sequence ID" value="KIC72476"/>
        <property type="gene ID" value="DB41_KK00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="172" mass="19747" checksum="F80FD81064BBBCD0" modified="2015-04-01" version="1">MHPISSASIESLPNELLLPILEACVAPPLFSVCKRWSHLLATEVMPSLYKQIGKVHAPQGNVKEQALIVDKIYKLEEKLSETAKVNAIFRQIFTLAKSFSTLEFKAQIEEKRYLTLANYSSYLLNINRLLLWKRLPGGEEYLSREEIKHLPLEKKESFLEIGLKKIVKTLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQM0</accession>
    <name>A0A0C1JQM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-dehydro-3-deoxyphosphooctonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-deoxy-D-manno-octulosonic acid 8-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">KDO-8-phosphate synthase</fullName>
            <shortName evidence="6">KDO 8-P synthase</shortName>
            <shortName evidence="6">KDOPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyoctonate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">kdsA</name>
        <name evidence="8" type="ORF">DB41_KC00060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the KdsA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386276.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000184.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72816">
        <property type="protein sequence ID" value="KIC72816"/>
        <property type="gene ID" value="DB41_KC00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1855"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019294">
        <property type="term" value="P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00056">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01362">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="7">
        <location>
            <begin position="8"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="273" mass="29621" checksum="21160C407C0C844F" modified="2015-04-01" version="1">MQTVPFRKFSIGKGQPLAILSGPCVIESEEHCLATAEALKNLFSKHNINLIYKSSYDKANRSSYQSFRGPGLEEGLRILEKVKKELDLPIVTDVHSPQEAQAAGQVCDLIQIPAFLCRQTDLINAAAQTGIPVTVKKGQFMAPWDMLNVVEKFRAAGNENIILTERGATFGYNNLVCDMRAIPIMQGFGVPVCFDATHAVQLPGGLGNSSGGQREFIPILAKAAISAGANCLFMESHPHPAEAKSDASSVLDFKDLPALLTILEKLYDLIQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JR23</accession>
    <name>A0A0C1JR23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JD00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000161">
        <property type="protein sequence ID" value="KIC73610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73610">
        <property type="protein sequence ID" value="KIC73610"/>
        <property type="gene ID" value="DB41_JD00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5695" checksum="BB1CC7952801DAE2" modified="2015-04-01" version="1">MFLLKPHFRNYRSMEINLRNVGYKMRGLLAAIAHAMQPPYKNQIYNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUT4</accession>
    <name>A0A0C1JUT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IT00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74146">
        <property type="protein sequence ID" value="KIC74146"/>
        <property type="gene ID" value="DB41_IT00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="10788" checksum="9A82E79267F49FEC" modified="2015-04-01" version="1" fragment="single">PVRFLALEDNHYIASMFHPEFKNFKLYQHTPAIKGCGIILPFLPDTYPGVNSHHIHASYDGRKLVFCDEHGWLHLWDFAHLQGKEPILVAPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV06</accession>
    <name>A0A0C1JV06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IR00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74231">
        <property type="protein sequence ID" value="KIC74231"/>
        <property type="gene ID" value="DB41_IR00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6353" checksum="E111E318710A166E" modified="2015-04-01" version="1">MAFKDAAIFQGANYFSKPTQMVPLKGMMNINIQGIPHLERIDLIGQVAGNWAINKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV59</accession>
    <name>A0A0C1JV59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpsR</name>
        <name evidence="6" type="ORF">DB41_IB00830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74950">
        <property type="protein sequence ID" value="KIC74950"/>
        <property type="gene ID" value="DB41_IB00830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="9921" checksum="54A261555A53108F" modified="2015-04-01" version="1">MRNMGQRYSEPGDFRSKKRKRCPFIAAGVKHIDYKDINTLSRFITERGKILPRRITGVSAYYQKHLTNAIKRARHMALLPFVAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVN5</accession>
    <name>A0A0C1JVN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent DNA ligase</fullName>
            <ecNumber evidence="2">6.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HW00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385487.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75105">
        <property type="protein sequence ID" value="KIC75105"/>
        <property type="gene ID" value="DB41_HW00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1372"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014144">
        <property type="entry name" value="LigD_PE_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13298">
        <property type="entry name" value="LigD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02777">
        <property type="entry name" value="LigD_PE_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigD_N" evidence="1">
        <location>
            <begin position="36"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="190" mass="21724" checksum="8BCA0391A833F1FA" modified="2015-04-01" version="1">MILKAYQQKKTFKTPAIPVPELSLDPCCSLPIFCIQKHAASHLHYDFRIECQGVLISWALPKGPSLNPYNKRLAIRVEDHPLAYRHFEGVIPPGNYGAGEVVLWDEGIYTLAGMKAKKDIENACLKGLEKGHLEIELHGHKLKGGFVLQQWKKEKNRNWLLIKRKDQYVDLKIDVLEHTQSVRTCFPTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW61</accession>
    <name>A0A0C1JW61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_II00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74621">
        <property type="protein sequence ID" value="KIC74621"/>
        <property type="gene ID" value="DB41_II00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="60" mass="6980" checksum="2A56CC47A3EA13CA" modified="2015-04-01" version="1">MQLYNQSVGLFTDLYQLSMSYGYWKAGLEYKEAVFQLFFAVLLFRGDLLLQQGLKPPLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWG7</accession>
    <name>A0A0C1JWG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386895.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71572">
        <property type="protein sequence ID" value="KIC71572"/>
        <property type="gene ID" value="DB41_AV00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="444" mass="47564" checksum="9A44E3C6125DA902" modified="2015-04-01" version="1">MTFTTPYVNISGMPSAIPTRLEYTNAKVASAYYNAIMAFVRVLQLQGSTTSSNAYPASLISALNVSEVNAALNQLTNLAKYGVIVTSSGQIIYPSSIVSAGFLAAHGLSAKVPPSAGKSSYNQHLMTMSMAQDYDAILRSLAAIGVNTNAAGSNIPQLSANQLKQWLDLAIQVSAVANAVQAAQLEGYGGARGLQSIIEIDYVQTGNQIISKNMAQLKSALNMTQQILDNLAELQNLHNQITTKSSAFNFNYGDGRGKDGPSAWSPGYQQAASAFYNKPITPVILPSIAPGSSGFVSAYKKLVNIRTQLTEQLKTLSAITSASDRSNVTSLYSRLTQVLTDLNTSFSVNGQPVLSTTPPGLASAGFRKWMLDNYSAFNSSDANAAGKFQQNITFAITASENLNDTQKETVRNYLYIFEEYYKSASAALQAISQIIQKMAQNIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWK2</accession>
    <name>A0A0C1JWK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HL00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385321.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75470">
        <property type="protein sequence ID" value="KIC75470"/>
        <property type="gene ID" value="DB41_HL00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1259"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014057">
        <property type="entry name" value="HI1420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40275">
        <property type="entry name" value="PTHR40275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02684">
        <property type="entry name" value="dnstrm_HI1420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="100" mass="10976" checksum="E3E4BD01085F4CEB" modified="2015-04-01" version="1">MARSKKYQEFLLKHLKDHDEAVAYLNAALEESLKGDEESQHLFLMALRNVAEAQGGVGALAKKAHVGRESLYKTLSGAGNPKWHTLVSLCVAMGLNLRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX31</accession>
    <name>A0A0C1JX31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HY00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385548.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74986">
        <property type="protein sequence ID" value="KIC74986"/>
        <property type="gene ID" value="DB41_HY00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1407"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="607" mass="67017" checksum="BF6112CF64909514" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY39</accession>
    <name>A0A0C1JY39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GU00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75970">
        <property type="protein sequence ID" value="KIC75970"/>
        <property type="gene ID" value="DB41_GU00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="106" mass="12253" checksum="3AF6BA91681C0A75" modified="2015-04-01" version="1">MAKSTLKTRPIFHWAPLRIKAHLLLCFINLFLERFLESLLRQNNVYLTLDRIRHALAQVHTTIFEDRSAKREGSMQSLLCQDAQAILQVLGIPTQRNTTFQSQCCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYC8</accession>
    <name>A0A0C1JYC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KR00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72182">
        <property type="protein sequence ID" value="KIC72182"/>
        <property type="gene ID" value="DB41_KR00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4985" checksum="CF0824733FF6D45F" modified="2015-04-01" version="1">MLYGARKANKRKDPQRALNPALQINLFLKLILLIPISLTFYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYP8</accession>
    <name>A0A0C1JYP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">tmk</name>
        <name evidence="5" type="ORF">DB41_GN00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384783.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76100">
        <property type="protein sequence ID" value="KIC76100"/>
        <property type="gene ID" value="DB41_GN00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.971"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="7"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="214" mass="24075" checksum="AFD42E535D15F4E1" modified="2015-04-01" version="1">MTLFITIEGGEGAGKTTLIEKLAAVLTSFGYAVVKTREPGGSRLSTHIREWLLNRNADLPIGYKAELLLFLAARAQHLEELIKPALEKGKVVLCDRFNDSTIVYQGIGRGLGMDYVKQICECVSENLNPDLTLFLDVDPQIGLMRTRKASKENAGRGEVDRIEAERLDFHKRVRQGFLSLARQSPERIRVIDANQAEDAVFRQAKQWLEEKVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZC1</accession>
    <name>A0A0C1JZC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GH00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000093">
        <property type="protein sequence ID" value="KIC76365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76365">
        <property type="protein sequence ID" value="KIC76365"/>
        <property type="gene ID" value="DB41_GH00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="192" mass="21445" checksum="FDC87858C83BE3F7" modified="2015-04-01" version="1" fragment="single">MMPPNSTPSTQVAFRATVSENIEDAVSGELMTRAVTLFPCGHTFNEDTVIQCLARNKLCPLDRKLIERHAPNYTVRQLAETADSHPLEELKHEPSEEAVGHFLWGKRLAEKGEHATAIEALLQALQLTPTYEKAQAYLEFCLKRSSEASSSSQQVTPLFSSKVKDKEKSLPSTDSPKERYTELLLDLLEESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZE8</accession>
    <name>A0A0C1JZE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75841">
        <property type="protein sequence ID" value="KIC75841"/>
        <property type="gene ID" value="DB41_GZ00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="240" mass="27797" checksum="19B2C849766CEE7D" modified="2015-04-01" version="1">MKVRFDKTLAAKSCKVQPKRKDYYSFTERINSVDVNIQKCSEDYNMKKLLLTGLVMCGLFVASHSYAQETSGAASAGAAFAQSQASSSQKGQEWNQNNQNTTEEHYWSHDGRRWHPGSCSIEGEDHPCADRAADAPTGECWCKYVHYEPCYYYTKRCVTENKYRTKKCTRQVPKYTEVQKCRMVPQYYTETVCKYETECYDVQECIPSKKWVSDRHVKYVPKYYYKHICGKSGCPTPCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZG8</accession>
    <name>A0A0C1JZG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lon N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75871">
        <property type="protein sequence ID" value="KIC75871"/>
        <property type="gene ID" value="DB41_GZ00350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1100"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="PTHR43718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="39"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="279" mass="31933" checksum="713B70AD5C191A3A" modified="2015-04-01" version="1">MNLEDIEDSSFTQQLENAVIKTLENQQKTEKRNSFPNELCIFPLLKRPFFPGMAAPIVIEPGPFFETLKLVAKTDHKSIGLILTRQEDVDIYKASFGDLYQVGVIARLLRIIPLEQGGAQVILNMERRLRVLRPLSNSKVLKAKVSYFEDSPTLTSELKAYAISIISTIKELLKLNPLFKEELQIFLSHSDFTEPGKLADFAVALTTASREELQEVLETFDIQKRIDRALLLLKKELDLSVLQNNINQKIESTISKSQKDFFLREQLKTIKKELGIRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZQ6</accession>
    <name>A0A0C1JZQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GW00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75941">
        <property type="protein sequence ID" value="KIC75941"/>
        <property type="gene ID" value="DB41_GW00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="8054" checksum="90CFD9DCFFB08094" modified="2015-04-01" version="1">MSLLYFVKNKFIFLKVIAKFILYFGNINPQMLKKRKFLIFLINRCAGFKGARQREDGLELGFFTNRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K077</accession>
    <name>A0A0C1K077_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GN00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76096">
        <property type="protein sequence ID" value="KIC76096"/>
        <property type="gene ID" value="DB41_GN00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="210" mass="24204" checksum="2CEC140B4E312C7D" modified="2015-04-01" version="1">MSPYQETLTSEVFFAKTREESLAAYYLPLFLNLKAKNLFLKFSCMFYIFLYIYIVLKTTKTPITFKDNHTMNPSSSITIEHLPNEILTPILKACASPSLFSVCRRWQQLLANEVMPSLYKQIGKMHVPQGDVNEQASILDKLYKLEEGLSKTTKVNTILKQIFTLAKSLSPLEFKGQIEEKRYLTLANYSSYLVNINRLLIWKKLPGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K085</accession>
    <name>A0A0C1K085_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferredoxin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fdxC</name>
        <name evidence="2" type="ORF">DB41_GN00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384800.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76111">
        <property type="protein sequence ID" value="KIC76111"/>
        <property type="gene ID" value="DB41_GN00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.982"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="9566" checksum="E59C032C8B199970" modified="2015-04-01" version="1">MAKLIFDHNGEEIELPDDSPIAEVCEEAGVPFACTEGVCGTCVILVKEGKENLSSPTQEEEDFLGEGTCDERLACQCRIKKGNVKISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0P5</accession>
    <name>A0A0C1K0P5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_ET00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383941.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76735">
        <property type="protein sequence ID" value="KIC76735"/>
        <property type="gene ID" value="DB41_ET00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="340" mass="40055" checksum="764496094610E25F" modified="2015-04-01" version="1">MAPKKPKSSPAQDSFIKEPAKKRLTILARFVDRIRSTFQRFQSKPLQEHPLVGRIQDLQSKASAVLIQLQSIKNELHKEIDAEAFVYIEEVIDPLIKEVSRLHKSIEQPRSVLHQAKTYQRYSQWVEKAKLWIQICSKTTDKEALFKAVIRYTIDEFLEVIDRDVQVITDYQEHMLEALSIDEEEKIDLAQRLEVRLQSYLHALNALRVKPENLPLKEIAVWKAQVDKRREKYFDAALHAIDKIVNQSLPDSRDEEENEDLKDALIQIAYLEKHIPPWYDEINLAETLTFTQKADFKSQLELWEQKIHRLNLDLRLTPELIERLKTLNEIIHYAQHKLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Y0</accession>
    <name>A0A0C1K0Y0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0158 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243803.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76805">
        <property type="protein sequence ID" value="KIC76805"/>
        <property type="gene ID" value="DB41_EI00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.503"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005361">
        <property type="entry name" value="UPF0158"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03682">
        <property type="entry name" value="UPF0158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="414" mass="48098" checksum="827017F3CB3701D5" modified="2015-04-01" version="1">MRSKTLKEAQNPLILRCHRLIEGFTKSDDERDFYLDRQEGFIIYVDLDKPQEEIEALEQELRQNSERYFLIPKLTFYETKKIMEGFVNEKVYDIDTKEKLLEIIQSKEARENFLEFIYDHLSELEKWQQFYQERSRIRIIEWLRNNQFHFVFEEDLDLPKSLLEKVKRHLFDTKVGKDILQARKALLAKAKTYYSNEALNPRPKRGRPPKQAVKQEFEPQIATDVYTTVPPSMRLFLFTPDLTASAVTFSSKFENEGQLLASRRHLHDGMDQNLQSINQKLAALRNLSTKWLDQDKSKPESKRFIEIADKVTINHFDGEEELEGEDFAFSADNNQAISKAIDVNGTPSTSSKPAKKPTQKSKDNSSSRKAKAVKASPKENKPKPLAKNSKIKLMDSKTAKGKPKQKIKANKPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K117</accession>
    <name>A0A0C1K117_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GB00110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76476">
        <property type="protein sequence ID" value="KIC76476"/>
        <property type="gene ID" value="DB41_GB00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="271" mass="31373" checksum="C321498DB8F441A3" modified="2015-04-01" version="1" fragment="single">MNPSSSFTIENLPNEVLTSILEYCPTPALLRVCTRWRHLLATEVMPSLYKQIGKMHVPQGDVSEQALILDKLYKLEAELPEIEKVNAIFKRIFSLGKSLSPVELEFQWKTAEKRYFTFSNYSLYFVNINRLLIWKKIPEGEEYLNQEEIKYLPLEKKGELFRDWIERHGKDITSLDLTEIGLTSLSPEIGQLPHLQTLNLENNQLTFLPAEIGQLPHLQTLNLENNQLTFLPAEIGQLFQLQWLHLNNNQLTTLPAEIGQLPHLQTLNLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K126</accession>
    <name>A0A0C1K126_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_EF00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000045">
        <property type="protein sequence ID" value="KIC76845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76845">
        <property type="protein sequence ID" value="KIC76845"/>
        <property type="gene ID" value="DB41_EF00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YfiO" evidence="3">
        <location>
            <begin position="44"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="YfiO" evidence="3">
        <location>
            <begin position="241"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="341" mass="39372" checksum="0B66C4AE9AC888AA" modified="2015-04-01" version="1">MRHLSIYIRLVFFTFCYLSSPYLEAAYTIKNGRIVDVDKLATLQPDQHFSLGQTAMNNGDWQEASRQFAIVSNNFPNNPYGQQSLYYLGIAEFNLKEYDFANKAFSAYLKCQNNPPYFLEAIEYKYAIAEQLRGGAKRRLLGTKQLPKWSTGKSLALAIYDEVITAMPSHEMAAQALYAKGCLLWEKREYRLSIESFQLLCSRFPKNELTPTSYVNISCIYYDLCQNEPQNPDVLAFAELNAKKFIHEFPKDERIDEVRQNVQQIKECYATALYETARYYEKIKQPRASLIYYSNAIKNFPDTLVAQRCRDRLEQMGFSHDARALAPLVFPVPSGKKDKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1F2</accession>
    <name>A0A0C1K1F2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JM00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386164.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73252">
        <property type="protein sequence ID" value="KIC73252"/>
        <property type="gene ID" value="DB41_JM00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="127" mass="14854" checksum="FBB5EEF7AB75D80D" modified="2015-04-01" version="1">MVNTLTNADNHKDGTTISPNDSTVTSIKQLPDELLVHIFSFLQAFDLLEVELTCHQWKNLANDETLWKDLCRKHFEKCWVDEKPYKESYFAAHRTKRRYEKTMAFLGSLKKVERNFELGIYMGIGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1P1</accession>
    <name>A0A0C1K1P1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_DN00060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243776.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76985">
        <property type="protein sequence ID" value="KIC76985"/>
        <property type="gene ID" value="DB41_DN00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="131"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="419" mass="47424" checksum="EFC126779E514781" modified="2015-04-01" version="1">MMKGTDGQAKPEGFFFEMAMNLSDPIISTSANDSKESLLQAQSFQKEKKVIKRALEVKEKELGKQNLKRKKYAIWKPRNLKIDTAMQKMLRNSRKAIEEHKEEDFLAYASYQSCLPILEDNLPTAPALSLEYVSAEAQGRRPRMEDVHLFQEILQGALVGVFDGHGGQQVAEQAKEEFEKIFSETLALNKGNVHLTFEQLIDEIHQNIIQHTYYDMIGTTLAISFIDKNTHLIYTATLGDTEANIYRNKESIALSCVRNWTHAKEAARAAIALEDPTLAETWPLAKNPKTLRYPNSRIGLNVSRAIGDKYASGKPDKPAVIHKPKITINRLRKGDILIIACDGLKDYVLENEIIAHVISEPQEKEEEPLVDLENTEEEEIEEEKTSWNNSPKNLAQRLVDYALEKNSADNVTVVVVKIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1X5</accession>
    <name>A0A0C1K1X5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76681">
        <property type="protein sequence ID" value="KIC76681"/>
        <property type="gene ID" value="DB41_FB00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5265" checksum="C78D3CB373050030" modified="2015-04-01" version="1">MPEEVNNVVNRLKKYPNLLESIRNLLNIAARVKGIEGADDAEFALIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K200</accession>
    <name>A0A0C1K200_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsmE</name>
        <name evidence="7" type="ORF">DB41_DH00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383418.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77055">
        <property type="protein sequence ID" value="KIC77055"/>
        <property type="gene ID" value="DB41_DH00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="232" mass="26055" checksum="992D1EF593E4A3ED" modified="2015-04-01" version="1">MPSTRFYLCSRLQAGQEVILEGNEFHHLAHVMRLEEGEQAEFVNGAGTLAIGVLKQREKKQATFIIESFTQQEKTSSELILAQGLPRLNRLDFIIEKSTELGATQIWLFPGQNSERKSLNEHQLKRMESLMIAAMKQCGRLYLPSLVIKPALHQWDLLKIPAFFGDVRETAPFFWHIHSPGKEALFFIGPEAGFTAAETERLGQMGAQGVKLHPNILRTDTAALVALSIMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K208</accession>
    <name>A0A0C1K208_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76706">
        <property type="protein sequence ID" value="KIC76706"/>
        <property type="gene ID" value="DB41_EY00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4254" checksum="41925B50B8D247C4" modified="2015-04-01" version="1">MQSSMHNACQHEANLEDESGMQLQIIPPFAKGSGIIKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2D1</accession>
    <name>A0A0C1K2D1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">uppS</name>
        <name evidence="3" type="ORF">DB41_CW00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383284.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77160">
        <property type="protein sequence ID" value="KIC77160"/>
        <property type="gene ID" value="DB41_CW00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.151"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="206"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="252" mass="29313" checksum="30BB0D92F6B69B5D" modified="2015-04-01" version="1">MNISVKNNYYTLEQKASLDPKRIPHHVAFIPDGNRRWAKRQQMRSIEGHQEGSDNLIEIVKAGKELGIKIFTFYLFSTENWSRPQEEIDALMWLLHTYLLEQQSSFVEEGTRLCTIGNIAALPEYVQKTIEETRQVTAHCQEADLIFALNYGSRDEIKRAVQSIAQDIIHKKIIPEQISEEIISQYLDTAPWSDPDLLIRTSGELRLSNYLLWQLSYTEIFSSNVLWPDFTPYHLLEALLNYQKRERRLGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2D6</accession>
    <name>A0A0C1K2D6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rplW</name>
        <name evidence="6" type="ORF">DB41_EH00150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383793.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76831">
        <property type="protein sequence ID" value="KIC76831"/>
        <property type="gene ID" value="DB41_EH00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.480"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="111" mass="12481" checksum="8EDD72FACEF40973" modified="2015-04-01" version="1">MSKKNPYQVVKHQHVTEKALVLKELKNASSNPSLKRCESPKYVFVVDRKANKTDIANAIEEIYSDRNVKVVAVNTINVKPKARRVRGRSGMKPGFKKAMVTLEKGDSLDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2H8</accession>
    <name>A0A0C1K2H8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CQ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000007">
        <property type="protein sequence ID" value="KIC77215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243743.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77215">
        <property type="protein sequence ID" value="KIC77215"/>
        <property type="gene ID" value="DB41_CQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="465" mass="52859" checksum="4D69EC6699241E11" modified="2015-04-01" version="1" fragment="single">MMPSTSTSNTHPNFPLAVSENIEDAVSGKLMTRAVTLLPCGHTFNEETVISCLARNKLCPLDSQLIVRHTPNPTIRLQSKIAEADFLSEFFRERYTALLGHLLNEPSIKGIPSLANLLENQFKILMSQFGEPLTEEEKISYYWTRDLLDENKKIRQFVFSRLQQTHPSAPLPVGVSLSPLSTSSSSGVPKEIGCYSHRFVPPPPISTVSLYNMILQVHFPEGNGELIEQTRIIDKIYKIDSHLSTEEKVLYIFQKLFTLASSLSPLGFEENIIGNKASNLSNYSSYLLNISCLLLWHRLPEGTEYLSRPYIYPLPLKRKAELLIPWMKEYCTQLNYLNLSYLNFIFLPPAIGQLSQLQRLYSHNNQLTTLPASIGQLSQLQRLYLHNNQLTSLPETIGQLSQLQRLYLYTNNLNTLPESIGQLSQLKELFLFNNRLSALPETIGRLCQLQYLFLSNNHLSALPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2K8</accession>
    <name>A0A0C1K2K8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DS00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383610.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76921">
        <property type="protein sequence ID" value="KIC76921"/>
        <property type="gene ID" value="DB41_DS00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002148061" evidence="1">
        <location>
            <begin position="21"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="175" mass="20163" checksum="AE1E33D2DF78CFB2" modified="2015-04-01" version="1">MNKILLFILYSLFIQSGMYAEAPRPKAILQAHLHAASTNPSDIKTMKIHPGSTVTLQAEIKNVGNLPSAPGKVYIRFVLIEPLEDLLQSRTFHTESILLPSLYPGQVTVVKFMKEHQWPSLQDFIKQNWNMRHYQAVVKIDGEKEEKVIGYLPIFFSAYYYEGHHREVPREVKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2L9</accession>
    <name>A0A0C1K2L9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DQ00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383595.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76941">
        <property type="protein sequence ID" value="KIC76941"/>
        <property type="gene ID" value="DB41_DQ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.367"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014578">
        <property type="entry name" value="Pesterase_CT488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033094">
        <property type="entry name" value="Pesterase_CT488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="2"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="250" mass="28953" checksum="1C74B17E82D3E478" modified="2015-04-01" version="1">MAVWALADLHLAFGTPEKKMDVFGEPWINYTEKIKKNWLNCIQPSDLVLLPGDISWAIQLEDAVIDLKWIHELPGTKVMIKGNHDYWWRSLTKIEKILPPSIHLIQNNAFHWEGYSIGGSRLWDSSAYDFNAYIEFKENPYAKILLEKSDKVAEAEKIFQRELQRLESSLKNLNPQASIRIAMTHYPPISADLKDSAVSQLLEKYHVNTCLFGHLHNVKKHLSLFGEKNQIRYILTSGDYLDFIPKLIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K361</accession>
    <name>A0A0C1K361_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylosuccinate synthetase</fullName>
            <shortName evidence="7">AMPSase</shortName>
            <shortName evidence="7">AdSS</shortName>
            <ecNumber evidence="7">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">purA</name>
        <name evidence="9" type="ORF">DB41_CW00100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383285.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77161">
        <property type="protein sequence ID" value="KIC77161"/>
        <property type="gene ID" value="DB41_CW00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.152"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="413"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="439" mass="48832" checksum="CE83C3E60A92D54B" modified="2015-04-01" version="1">MPQVILIGAQWGDEDKSKIIDILTAQAKHVIRSQGGNNAGHTAVLDKQEYKFHLISSAILHSHTHCYIGAGTVIDPEVLIQEMEDLESKGVHIKGRLLISPSAHIIFPYHRMLDYLLEQKKGERAIGTTGRGIGPCYADKAQRLGIRMGELVRPDIFGKLLKSILQLKNEELTKLFGAEKLNEEEIYKKYSRYAELLKPFVAEVEELIHQAIDNKENILFEGAQGTFLDTSLGTYPYVTSSSTIAGGICAGAGVGPTCIDHTLGVVKAYTTRVGNGPFPTEFQENESFLNHPITSEYSNTVGRRRRLGWFDAVLARTAVHINGIDSLAVTQLNSLDYLDPIKVCVGYQIHGVRINHLPYISEDLDKIVPIYETIPGWNASTSQITNYKELPQNAQKYLSKIEQLCRVPINIISLGPQREKTLILKDLFSTKEKAACKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K564</accession>
    <name>A0A0C1K564_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IO00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000146">
        <property type="protein sequence ID" value="KIC74437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74437">
        <property type="protein sequence ID" value="KIC74437"/>
        <property type="gene ID" value="DB41_IO00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="236" mass="27284" checksum="AE66FBF5A96BFAB9" modified="2015-04-01" version="1" fragment="single">MHPISSASIESLPNELLLPILEACVVPSLFGVCKRWHHLLASEVMPSLYKQIGKVHVPQGNVKEQALIVDRIYKLEEKLSEAAKVNAIFKQIFTLAKSFSTLESKEKTEEKRGLRLANYASYLLNINRFLLWKKLPGREKYLSREEIKHLPLVEFKEKTEEKRGLRLANYASYLLNINRLLLWKKLPSGEEYLSGEEIKHLPLEKKGELLRDWIEENCKDLTFLNLSKAGLIYLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5D7</accession>
    <name>A0A0C1K5D7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tail-specific protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsp-B</name>
        <name evidence="5" type="ORF">DB41_IM00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000144">
        <property type="protein sequence ID" value="KIC74502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385992.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000144.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74502">
        <property type="protein sequence ID" value="KIC74502"/>
        <property type="gene ID" value="DB41_IM00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1626"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040573">
        <property type="entry name" value="TSP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17804">
        <property type="entry name" value="TSP_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="258"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="698" mass="79001" checksum="88D81BC4ED7544FC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6L4</accession>
    <name>A0A0C1K6L4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385701.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74887">
        <property type="protein sequence ID" value="KIC74887"/>
        <property type="gene ID" value="DB41_IB00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="96" mass="10783" checksum="16277E7F5FB28E08" modified="2015-04-01" version="1">MELIDQIQFYSTRLINGDCLNNFRFNNTSEIREILIARIASVALIAGIITAFFTITWAPMVFIVAGVAAFAYYTAEGLEPPSKEYVTNVIEKIRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6T5</accession>
    <name>A0A0C1K6T5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADP-L-glycero-D-manno-heptose-6-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">ADP-L-glycero-beta-D-manno-heptose-6-epimerase</fullName>
            <shortName evidence="3">ADP-glyceromanno-heptose 6-epimerase</shortName>
            <shortName evidence="3">ADP-hep 6-epimerase</shortName>
            <shortName evidence="3">AGME</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">hldD</name>
        <name evidence="5" type="ORF">DB41_IB00800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ADP-D-glycero-beta-D-manno-heptose = ADP-L-glycero-beta-D-manno-heptose</text>
            <dbReference type="Rhea" id="RHEA:17577"/>
            <dbReference type="ChEBI" id="CHEBI:59967"/>
            <dbReference type="ChEBI" id="CHEBI:61506"/>
            <dbReference type="EC" id="5.1.3.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
        <text evidence="3">Binds 1 NADP(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; ADP-L-glycero-beta-D-manno-heptose biosynthesis; ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homopentamer.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.20" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385766.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74947">
        <property type="protein sequence ID" value="KIC74947"/>
        <property type="gene ID" value="DB41_IB00800"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1516"/>
    <dbReference type="UniPathway" id="UPA00356">
        <property type="reaction ID" value="UER00440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008712">
        <property type="term" value="F:ADP-glyceromanno-heptose 6-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097171">
        <property type="term" value="P:ADP-L-glycero-beta-D-manno-heptose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05248">
        <property type="entry name" value="ADP_GME_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01601">
        <property type="entry name" value="Heptose_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011912">
        <property type="entry name" value="Heptose_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02197">
        <property type="entry name" value="heptose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="4">
        <location>
            <begin position="9"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="207"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="17"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="80"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="328" mass="36906" checksum="81FE0641513399D1" modified="2015-04-01" version="1">MKAFSDQYIIITGGAGFIGSGVVRYLNDRGISNLILVDDLGASEKWKNLVGKCFIDILDKSQLLTWMVGREDAIKAFIHLGACSSTLERNASYLLENNYRYSVKLAEYAFTHGQRFIYASSAATYGDGTQGFLDNENQLESLQPLNMYGYSKHLFDLWLKNQRVLNKVVGLKYFNVFGPNENHKGQMASAIVRMLPAAQHENVVRLFKSSEPSKYPDGGQKRDFVYIKDVARMTCAFLFNKVNGIYNIGSGNASTWNDLASSVFKAIHKPVKIDYVNMPDELIGKYQNYTCADMTKTRHALQEQATSLPLEAAVEDYICNYLIPGKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K863</accession>
    <name>A0A0C1K863_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA ligase</fullName>
            <ecNumber evidence="10">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">ligA</name>
        <name evidence="12" type="ORF">DB41_HN00140</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385359.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75382">
        <property type="protein sequence ID" value="KIC75382"/>
        <property type="gene ID" value="DB41_HN00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1292"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="587"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="10">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="30"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="79"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC75382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="663" mass="74563" checksum="39EE6BB8CCC7F1F8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K8D5</accession>
    <name>A0A0C1K8D5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HL00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385323.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75472">
        <property type="protein sequence ID" value="KIC75472"/>
        <property type="gene ID" value="DB41_HL00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="308" mass="35139" checksum="662AA376BB4D52C3" modified="2015-04-01" version="1">MILTTLLASLALLTSSNCSETKEDDNLLIRALQKQQIDARSVIWDDPQNNWKDYQAVLVFSTWDYHTDKFNFFLQTLSDIEKQGIPLFNPLSTIRWNASKVYLKKLAEKGVKVIDSIYLSSKDLKNLPNLLEKYGWEECVIKPSISASGDHTFRFNSSTVQKMQDHFKDYPYDLIVQPFMKEIMTEGEWSFIFFEKEFIHCVLKKPADGQFLVQSAHGGSVQPITPPNWMINEVKKILLATEQPYLHARVDVIKKGSALAVVEVEMIEPSLFLSYFPGSADKLAQKIKERLSASLTPLEPRAKGRASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA21</accession>
    <name>A0A0C1KA21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GS00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000104">
        <property type="protein sequence ID" value="KIC75982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384863.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000104.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75982">
        <property type="protein sequence ID" value="KIC75982"/>
        <property type="gene ID" value="DB41_GS00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="10127" checksum="646E2A623155FD89" modified="2015-04-01" version="1">MTKFKRTPREYNPMKDLLDEELIAKAVWECLKENDPDGVIEILEAHISAKNKSQLAREHDLPRTTLYHAFKSKNPTLHTLAKLVNATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA38</accession>
    <name>A0A0C1KA38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GR00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75992">
        <property type="protein sequence ID" value="KIC75992"/>
        <property type="gene ID" value="DB41_GR00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="6267" checksum="C8971F6F47CE220B" modified="2015-04-01" version="1">MDLKSNKILFQIILLIKVLEKVVEKKLWRYNFSFSTINFDQFLFLIEKRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBQ4</accession>
    <name>A0A0C1KBQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76562">
        <property type="protein sequence ID" value="KIC76562"/>
        <property type="gene ID" value="DB41_FN00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7324" checksum="7BA31E353FA833B9" modified="2015-04-01" version="1">MDESIEKSVVNFSLQKPAYGQLKICNKLEEIRSFYFDGRWAFCLVKDTIFKTFQKRLKALEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCJ3</accession>
    <name>A0A0C1KCJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">rpsK</name>
        <name evidence="10" type="ORF">DB41_EI00170</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383825.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76802">
        <property type="protein sequence ID" value="KIC76802"/>
        <property type="gene ID" value="DB41_EI00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.500"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="137" mass="14433" checksum="14E35D5098D3ABC5" modified="2015-04-01" version="1">MSKQSATTTTKKPVKAKKRSHQNVPSGIAFVKATFNNTIIAITDPSGRVISWSSAGKVNFSGSRKSSAFAATVAAQDAGKAAMSLGMKEIEVNLKGPGAGRESAVRGLQSTGLLITAIRDTTPVPHNGCRPRKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDR4</accession>
    <name>A0A0C1KDR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DB00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77112">
        <property type="protein sequence ID" value="KIC77112"/>
        <property type="gene ID" value="DB41_DB00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6170" checksum="B212937F60DA2141" modified="2015-04-01" version="1">MKNKLMDEQIEAQTAIKESIKLLDSLNILIQLRLVSEKIFANPINKLYLSLKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1J6</accession>
    <name>A0A0C1H1J6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III secretion specific chlamydia chaperone 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">scc2-A</name>
        <name evidence="3" type="ORF">DB41_AV00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71569">
        <property type="protein sequence ID" value="KIC71569"/>
        <property type="gene ID" value="DB41_AV00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011716">
        <property type="entry name" value="TPR-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07720">
        <property type="entry name" value="TPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="214" mass="24952" checksum="02BB37676981B7DB" modified="2015-04-01" version="1">MKENLSMAEETQDFNPEEFRKAIKKTVDAHRGKLSEEEVKLQEQALIDIFENGMLPAQALGFDVNFMDYVYKFAYTLYQKNEIEEASQLYRWLKVMVPIDQKYTIALAHCYIQQKNWLAAVAMLMELGVLNPEDPLPFEKMCDCLIEAKDYASALMAIEQAIKRAADKQEYMLDKEKWLMTYDYLLSQLEIDPAIIEKVKAENESITHVKNSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1L7</accession>
    <name>A0A0C1H1L7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 5">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rmlA</name>
        <name evidence="7" type="ORF">DB41_AV00290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 5"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386931.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71589">
        <property type="protein sequence ID" value="KIC71589"/>
        <property type="gene ID" value="DB41_AV00290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2267"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC71589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="297" mass="32751" checksum="65F07D94CF4408E3" modified="2015-04-01" version="1">MKGIILAGGSGTRLHPLTLGVSKQLLPVYNKPMIYYPLSILMLAHIQDILIITTAEEQFLFKRLLGDGSQYGLSLSYAVQAKPNGLAEAFIIGQDFIGNDAVCLILGDNIFYGNHLGPLLEKALSKTLGATLFGYEVKSPERYGVAEINEKGLVISLEEKPTQPKSNIAVTGLYFYDNQVVKIAQTLKPSARGELEITDINRVYMEKGQVSLNVMGRGFAWLDAGTYESLMQASQFVQVIEERQGYCIAALEEIAYHQKFISLEQLYALGEKLGKSGYGQYLLDIAEKENNILKGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H376</accession>
    <name>A0A0C1H376_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription elongation factor GreA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">greA</name>
        <name evidence="5" type="ORF">DB41_AA00150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386562.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72034">
        <property type="protein sequence ID" value="KIC72034"/>
        <property type="gene ID" value="DB41_AA00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2087"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="4">
        <location>
            <begin position="570"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="3">
        <location>
            <begin position="649"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="721" mass="83605" checksum="B435F9D4ABCB161D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3L4</accession>
    <name>A0A0C1H3L4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72119">
        <property type="protein sequence ID" value="KIC72119"/>
        <property type="gene ID" value="DB41_KU00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="101" mass="11598" checksum="7C1470BDC5B3538C" modified="2015-04-01" version="1">MDEKRNDALKVIQSLGADNEARQLWKKLCGYHRRSLAETAMYRFKRSFGGDFRSRKLAYQQAELYAKSLAMNKTTKLGMPQRALGANLGIVLNRRAIRSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H7Q0</accession>
    <name>A0A0C1H7Q0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptide chain release factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfC</name>
        <name evidence="5" type="ORF">DB41_JJ00010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000166">
        <property type="protein sequence ID" value="KIC73469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73469">
        <property type="protein sequence ID" value="KIC73469"/>
        <property type="gene ID" value="DB41_JJ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1759"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04169">
        <property type="entry name" value="RF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041732">
        <property type="entry name" value="RF3_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="15"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC73469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="466" mass="52028" checksum="264D1E9CE49F67D5" modified="2015-04-01" version="1">MSPLENKVDLQAEIFKRRTFAIISHPDAGKTTLTEKLLLYSGMLHTAGIVRGRKGRKAAASDWMAMEQERGISITSSAMQFPYKETLINILDTPGHEDFSEDTYRTLTAADCAIMVIDAAKGVEKQTRKLFEVCRLRKIPVLTFINKMDMPGRDPLDLMNEVENVLGIQSTAFNWPIGCGASFKGVYDRLEKQVLLFAKTSVGGAQKAEITRYPLNSPEIVLLMGEEAHHHLMQELELLEMAGNPFDYKHFLAGNVTPVFFASALTNFGVEPFFDAFIHLAPPPQPRLVNLNNGEEKTLDPVEAPFSAYVFKIQANMDKKHRDSMAFLRICSGRFERDMLVKHHRTAKEVRLSRPHGMLAGERTIVDTGYAGDVIGVINPGVFSVGDTISTKGGFNFKPIPHFQPEIFAHVSPKDVGKRKSFDKGVYQLTEEGAIQLLKPYEYGAELIFCCCRAATVRSDAIPLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H815</accession>
    <name>A0A0C1H815_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PqqC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JH00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386138.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73544">
        <property type="protein sequence ID" value="KIC73544"/>
        <property type="gene ID" value="DB41_JH00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034641">
        <property type="term" value="P:cellular nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046483">
        <property type="term" value="P:heterocycle metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901360">
        <property type="term" value="P:organic cyclic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027572">
        <property type="entry name" value="Fol-rel_CADD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039068">
        <property type="entry name" value="PqqC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40279">
        <property type="entry name" value="PTHR40279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04305">
        <property type="entry name" value="fol_rel_CADD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="1">
        <location>
            <begin position="17"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="230" mass="26488" checksum="79A63D2A01D8A3FB" modified="2015-04-01" version="1">MTQEFLNKIDSQIQDKHLLNHPFYQAWSRGELSKECLVEYAKEYYQHVKAFPRYLSALHSHTEDADTRRHLLNNLIEEEAGLPNHPDLWKNFTQQLGASTEEIEAHRPSPSMQAIIHTFMESCKNSSTAEGIASLYAYESQIPSICISKIKGLKEHYGMQEPSHWKYFSVHIEADKEHAAVERKLLERYANKSNEALIAASVERTLLVLWNFLSSLCTRYQLACSTSESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8E4</accession>
    <name>A0A0C1H8E4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CH00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000253">
        <property type="protein sequence ID" value="KIC71133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71133">
        <property type="protein sequence ID" value="KIC71133"/>
        <property type="gene ID" value="DB41_CH00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4779" checksum="03868D3457C56099" modified="2015-04-01" version="1">MVLVWVKGKVNLVHKELVVEVINCAIWVVCVGVVLEALVHIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9N1</accession>
    <name>A0A0C1H9N1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ATP-dependent helicase</fullName>
            <ecNumber evidence="5">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_AV00180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386911.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71578">
        <property type="protein sequence ID" value="KIC71578"/>
        <property type="gene ID" value="DB41_AV00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2254"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="55"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="711"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="1001"/>
            <end position="1147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC71578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1161" mass="133503" checksum="F5653F859B6A6802" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9X4</accession>
    <name>A0A0C1H9X4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">ftsY</name>
        <name evidence="7" type="ORF">DB41_IT00020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386057.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000151.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74139">
        <property type="protein sequence ID" value="KIC74139"/>
        <property type="gene ID" value="DB41_IT00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1676"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="6">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="114"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="196"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="260"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="309" mass="33785" checksum="2D90AB11D2952897" modified="2015-04-01" version="1">MILDFLKGSYTRLKKALSKTSAVLGHKLKALFTKPLNEETLEQIERTLYEADLGVKMSATLTEKIRQLHISHPLLKPEDLVKEIQQEIIQSLKSPSLSVPAMDSSIPHVILVVGVNGNGKTTSAAKLAKFYHSQGKKVLLAAADTFRAAAVEQLERWAQLLNIHIVKGAAKSDPASVAFDAVTAAKAREADILIIDTAGRLHTKANLMQELEKIKRSCHKVQNSTPQEILLVLDATTGQNAIDQATIFHKHTPITGLILTKVDGTARGGIAISIQQQLGIPIKYIGFGEGVEDFEPFNAERFVKALFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA53</accession>
    <name>A0A0C1HA53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AQ00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71718">
        <property type="protein sequence ID" value="KIC71718"/>
        <property type="gene ID" value="DB41_AQ00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4576" checksum="D468E4EF26646997" modified="2015-04-01" version="1">MIATQKHATSGRPKAEQKPSISSYHLQGTVTCSLLNKLANAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA64</accession>
    <name>A0A0C1HA64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosolic non-specific dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cndP2</name>
        <name evidence="2" type="ORF">DB41_IR00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.18" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244003.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74239">
        <property type="protein sequence ID" value="KIC74239"/>
        <property type="gene ID" value="DB41_IR00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1670"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103046">
        <property type="term" value="F:alanylglutamate dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="201"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="461" mass="51324" checksum="EC2325F353AC821F" modified="2015-04-01" version="1">MPNSFPSLHVLQDYYKKQEKNALEEYFTFLRFQSISSEIGYKSQMEACAQWVMSYLKRMGFEAEIWPTKGHPVIFASYMRAGPSQPTLLIYNHYDVQPVDPLEAWHTPPFDPTIRHGEVYARGAQDNKGQCFYTLFALKALMNIDGKLPINVKFCIEGEEECGSLGLSELLAHKKKELEADYLAIVDLGLRHPTAPAVTLGVRGIVTMDVEVKGTKTDLHSGSYGGIAYNPLHALVDILSQLRDSTGCIRIPDFYKDVQELSPEEKQRITFDFDEQEYFSTFGAKPTGGEKNYTPLERSWLRPTIEINGISGGYAGEGFKTVIPSQAIAKLSCRLVPHQSPEEAAKKIANFIEQKAPEGVEVKVHIHAGGGKAVRVEPSSKCVQAFAKAYEEVYKTSCAFTYSGGSIPIIQQLSEASQSEVVLMGLGLPDDQIHAPNEHFGIDRLEKGYLIIARTLEFLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC81</accession>
    <name>A0A0C1HC81_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HY00300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243963.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75004">
        <property type="protein sequence ID" value="KIC75004"/>
        <property type="gene ID" value="DB41_HY00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="215"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="412" mass="46524" checksum="21096693AF9E9A94" modified="2015-04-01" version="1">MNSPIHLQSDASTIPQVELPHSSLVVQNVAEESSLTDSLAKKSEADELLDSRLVVNTEVLIDDAPIPLFDLCIFEQTQGEKKRELIKQFGDGLKNIGFVAVKVEALQPLIEAAYLEMEKYFNQPLEEKMRDCQEDPSIGFSPQGRETAAGAYHPDLKETFSIPPNFKEWPANRLKFQEIMSLYHQQFTKLAALFMGYLAEYLNEPPENILIPAMSGNHLLRLAHYPAPKAEDDPQAVWASAHEDLNLLTLLPSAKVPGLQVMTKEGEWKHVNIPKGYILINTGEQLYYKSAGLIRAPRHQVINPGGLYARQRRFASLFFFSWPANFSLIPFAGCLNQVMADMPEGEKEEYIKNFPEMTVQECLEARLIEMRIILEPSEELVKTLSQKGLLKMPPHELIALYPSIFSDEQKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE18</accession>
    <name>A0A0C1HE18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative bumetanide-sensitive Na-K-Cl</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_HI00080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385282.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000119.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75654">
        <property type="protein sequence ID" value="KIC75654"/>
        <property type="gene ID" value="DB41_HI00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1242"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015377">
        <property type="term" value="F:cation:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="PTHR11827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="6">
        <location>
            <begin position="29"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12" evidence="7">
        <location>
            <begin position="481"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="751" mass="83212" checksum="4A59CDEC4338DB34" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE37</accession>
    <name>A0A0C1HE37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JV00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386233.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000178.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73013">
        <property type="protein sequence ID" value="KIC73013"/>
        <property type="gene ID" value="DB41_JV00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="497" mass="56868" checksum="5C47CA2F21BB0881" modified="2015-04-01" version="1">MAIDKTQFSDAIDHANKNVFDSYFHLKNVSRKEGGHRFKKLESQESGYSWGASHLNMKELLKNTAKIISYFTVIIPLIMLIGKAIHDYRHQYKIIKELPSDKIKNVSTKILNKTLGDEDKKEIMAFPEVSKLSESSRDGKAREKDEEDLPAAEAALILNIIKDLKEKLQAEEPALIDAQTEEHGIKIQKGELEGIEFEINSYGNYGITGWKIIREGQAYEVNEYAPQAYHGPKTEGFIERQRLLIDAAKWHVKNLPIGDSLEGQKAQEKLLETLDYLQRNFMQEIRSEKFQIDPQYIQHPDKKVGEDHYMQVHKIAQELLAQLAKDIQFTINQLNQVEEFTIDKLAQAEKDFIVAVGRPTIINTYFLGDSNQQFFHMQKPSSIINEKGERMARAMLPSTVRDREGLANYVATSFGEIHYREGEDFLETLFDAIRHSSYPPIAIKDTLQRQAIGCRNCKQNLIDLAAVRIQADPSLVTTPNRPLVLPLRTMMLLSPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE67</accession>
    <name>A0A0C1HE67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HH00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385199.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75714">
        <property type="protein sequence ID" value="KIC75714"/>
        <property type="gene ID" value="DB41_HH00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002151132" evidence="1">
        <location>
            <begin position="19"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="6639" checksum="10AA751DAFD71850" modified="2015-04-01" version="1">MKKTFNLLSLAIVATALTGCGCGWWSNSETGTSCAPRACEPRQAPSPYIWENTTSSDTTYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEA8</accession>
    <name>A0A0C1HEA8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">def</name>
        <name evidence="3" type="ORF">DB41_HG00190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385178.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75764">
        <property type="protein sequence ID" value="KIC75764"/>
        <property type="gene ID" value="DB41_HG00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1190"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="178" mass="20188" checksum="D2CFBB6DF535F137" modified="2015-04-01" version="1">MILQLAYYGDPILRKKTETIKEFDSDLRQLAANMLETMYAEKGIGLAGPQVHQSIAIFVTCVPTYINDETTLPGVERIFINPKILSYSEESDTLPEGCLSIPKVSGLVTRPLKIVVQAMDLDAKTFTEEFVGYEARCILHENDHLNGKLFIDRIASRSDRQNLESKLREIKKKYSFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEL6</accession>
    <name>A0A0C1HEL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mmaB</name>
        <name evidence="6" type="ORF">DB41_GZ00480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75884">
        <property type="protein sequence ID" value="KIC75884"/>
        <property type="gene ID" value="DB41_GZ00480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1115"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="6"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="199" mass="22339" checksum="520B7010BBC0652D" modified="2015-04-01" version="1">MAKIKIYTKTGDKGETSLFSGQRVLKDDPFIGALGSVDECNSAIGAALSLLPNDPQLQLTRKQLETIQHTLFDLGAAIATPLSQASASKVERTRFDQEGIEFLEKWIDLMEEQLPQLHTFILPGGHPAGAFLHLARSICRRAERDVIPLSRKADISKNVTIYLNRLSDYLFVCSRYVNHLCKQPETFWTMHKHSSLIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEU8</accession>
    <name>A0A0C1HEU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="7">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">tyrS</name>
        <name evidence="10" type="ORF">DB41_GU00130</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384881.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75964">
        <property type="protein sequence ID" value="KIC75964"/>
        <property type="gene ID" value="DB41_GU00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1033"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="9">
        <location>
            <begin position="357"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="230"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="47699" checksum="45D3F6AB26DA3815" modified="2015-04-01" version="1">MPSLIETLAERGFIEACTSDELKDILTQPTKVYCGFDPTADSLHLGHLICMMGLAWFQRFGHTPYVILGGATGMIGDPSGKISERQILDEETLLKNLIGIRKNFEKILDTHGRPNATVFLNNYDWFKNFSFVSFLRQIGKYFRMGPMLSKDSVKGRMTSEEGMSFTEFAYQALQGYDFLHLFQNYGVKVQIGGSDQWGNITAGTELIRKALGQSSYGLTFPLLTRSDGQKFGKSEKGAIWLSADKLSPYEFYQYLVRVSDVDVIKMMRMLTFMDMEEIRKYQAQMQQPDYVPNTAQKRLAKEVTRIVHGEENLKIALGVTEAAAPGAKANLDATTLELMAQNMPSRILNNKTVINAKLLELICQVGLLPSKSEARRLARNGGIYLNNNKVEDENYIIQPDDLIANRLMLLAVGKKNKILISIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEW0</accession>
    <name>A0A0C1HEW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GT00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000105">
        <property type="protein sequence ID" value="KIC75974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384865.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000105.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75974">
        <property type="protein sequence ID" value="KIC75974"/>
        <property type="gene ID" value="DB41_GT00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="332" mass="39919" checksum="4FAB93D5DBC5078B" modified="2015-04-01" version="1">MEINSIKLPSFNILIFSQTKREKFLDFITWIFFRLSLLWDERQREEYHQFFEIKRLSVAENTPEMTKLFKEKVLALCQKISDESITQHMKRLNGGKLGYQLYFNAIGDNKAFIKAHEVFEMLSMKWESGVPFNRDRFSAFWPAHKQAIRIENIFLQALAFEKEIPLSTDALEYCRIYDDMSLSFPISVYRSSFDLESTEKNLTKNIEAMPNDPNEIDNFCDFFSQLLTQWSPRYKIGLCQRYLFSQLSKNYPDKKLYLITLLRALEKDEIYHKYSLETILTKLKVHLQNFNLLEYWREESIIEDDEFFIRDPIYIPFEIHEHYDHLKDSFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG83</accession>
    <name>A0A0C1HG83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_8</name>
        <name evidence="3" type="ORF">DB41_JB00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000159">
        <property type="protein sequence ID" value="KIC73678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73678">
        <property type="protein sequence ID" value="KIC73678"/>
        <property type="gene ID" value="DB41_JB00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1715"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="410" mass="46883" checksum="9C269FDED928FE1B" modified="2015-04-01" version="1">MLATEVMPSLYKQISKMHAPHRDVNEQTLILGRIYRLEEELSETAKVNAIFKQIFALASSLSPMELEFKCKAEKKRYFTLTNYTSYLVNINRLLMWKNLPSGRKYLEQEKIKYLPLTKKGELFREWIENHAKDIKELDLQGVGLTFLPTEIGQLSQLAILNLDRNQLTSLPAQIGQLSQLQELKLNCNELIILPVEIRQLWELNKLYLNNNQFTNLPAEIWQLVGLQHLYLENNQLTSLPAQIGQLSRLSQLCLSSNELTSFPAEIGQLSQLQTLELSSNQLATLPAEIGQLSQLTWLSLSNNQLTTLPTEIGQLSQLQRLHLNNNQLTTLPAEIGQLSWLLELYLSNNQLTSLRAEIGQLSQLRVLNLCNNQLSSFPAEIAYLAEGLNLNLKENPLESIPEEIKQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGD5</accession>
    <name>A0A0C1HGD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ZT_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_GD00020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384566.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000089.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76424">
        <property type="protein sequence ID" value="KIC76424"/>
        <property type="gene ID" value="DB41_GD00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.864"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="234"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="314" mass="35130" checksum="7F5219FE8D719DEB" modified="2015-04-01" version="1">MSHYPDPVKLPSYVSIARRERNRQLILSAKRGVYIRLLIIWAESMGAWAFASSALTLDAISSFVDVFFSISLIYFIKFAERPPDKNHPFGHGRFEPLVGMQIGIVIVLIGLLAFFQQLFHLFADNNELRAAAAYAWIIPALAVFLLEICYRLVIKTARKQNSPALAADALHYRLDSITSAIAALALILGSYFPVLSALIDHLGAQAIACFMIGIGVYAAKNNLYQLIDKIPAKEYFDKVRSAALSVEGVEETEKIRIQQYGPDAHINIDVEVDPHMSVMLAHQITQNVRVEIQKAWPAVRDVIVHVEPYYPGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGF4</accession>
    <name>A0A0C1HGF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_GC00060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384500.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76439">
        <property type="protein sequence ID" value="KIC76439"/>
        <property type="gene ID" value="DB41_GC00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.833"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="109" mass="12085" checksum="FB4390772CFD2888" modified="2015-04-01" version="1">MKWSAWITLTYALIVMSGGMVGFIQAHSYPSLIAATLSATLLFIGAIGMFRKSILAYTLVVFIHLLLTLFFTYRYAITTKFMPAGLMIILSASSLIFILTKGKKKARLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGL7</accession>
    <name>A0A0C1HGL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UPF0118 membrane protein YueF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yueF</name>
        <name evidence="7" type="ORF">DB41_GA00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76484">
        <property type="protein sequence ID" value="KIC76484"/>
        <property type="gene ID" value="DB41_GA00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="356" mass="40909" checksum="4AAB8D7DB0EEA898" modified="2015-04-01" version="1">MWYNQKIFSNALLSLVILLTLFIGFQLFPFFKLVFQFVTTLLLPVIIAGLFYYIFRPIVRYLDQTKIPRYLVIIFIYLFVMVAGSLLISIVWPYIERQITAFRSFPQQKLKEVENKTVDLMNVFNFYSLSPEQLRNLFYHYLQEITQWASGGIVSSISSLTTVASYFFITPFILYYFLKDDQHAFEKFINHVPFIYRERATKALNDIDEILSSYISGQIIIAFIVGVLVFIGYWGIGLDYAFLLALIAGLFNLIPFFGTLISTLPALLVGLTSTPFMGLKVLAIVLIVHLIDLNFISPRIVGKRLNIHPITIIILLATSASLFGFWSLFFIVPLYAILKTLSIDLWERNVAEKMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH73</accession>
    <name>A0A0C1HH73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative acyl-CoA desaturase</fullName>
            <ecNumber evidence="9">1.14.19.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_FD00030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384077.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000066.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76644">
        <property type="protein sequence ID" value="KIC76644"/>
        <property type="gene ID" value="DB41_FD00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.643"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="45"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="374" mass="44556" checksum="0BC6A16DBCC53D25" modified="2015-04-01" version="1">MINLKKGVNWSPTIFLIIFQVALIIWLPFYFYYNRPTLSMVAASVVLLYATGLSITGGYHRFYSHRSYKTNFFLEWLLLFFGSMAGQGSALRWSYDHRLHHAFVDTDKDPYSIQKGFWYAHFLWIIEKPQPINPKVVSDLISNPVVVFQHRFYVFLFILTNSLVFLSLGWFLNDYTGALTFAVGVRLFCLYHSTWFINSLAHTWGDQPFSQEHSAVNNYIISFLTFGEGYHNYHHTYANDYRNGIYWYQFDPTKWLIWLLSKLGLAYHLRTTDKYTIKKRMVTEHAYLLREKLVKSWESKRIEWEPIINELSSNLVRKMTDFSQLKSRYRELKTQCTEAPLLKEIKKEMKALQKSLRQDWKKWWQLSKTIMSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH83</accession>
    <name>A0A0C1HH83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384026.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76659">
        <property type="protein sequence ID" value="KIC76659"/>
        <property type="gene ID" value="DB41_FB00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7580" checksum="8EF6B8BC6A658BD9" modified="2015-04-01" version="1">MNLSVKDYHPQLSVPSVQESFPQAFFLEKNLSFFWKILGASLLKFSKFCYELSYYLLTGHLKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH86</accession>
    <name>A0A0C1HH86_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein DB41_FB00060</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FB00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384029.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76664">
        <property type="protein sequence ID" value="KIC76664"/>
        <property type="gene ID" value="DB41_FB00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="104" mass="11292" checksum="4C368FB06B122CDB" modified="2015-04-01" version="1">MGSGFSKQKKQAKMLQDQFSKLQTQLQATEVVGSAGNGLVSITLSGEHELKQIKIKPECVDPEDIEGLEDLIKAAYKDAFTKLKEQNPKLPSLPGMPNLGGFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHC5</accession>
    <name>A0A0C1HHC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EY00150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383987.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76704">
        <property type="protein sequence ID" value="KIC76704"/>
        <property type="gene ID" value="DB41_EY00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="610"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="649" mass="71579" checksum="AA084F6789C9D830" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHD3</accession>
    <name>A0A0C1HHD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EV00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000060">
        <property type="protein sequence ID" value="KIC76719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76719">
        <property type="protein sequence ID" value="KIC76719"/>
        <property type="gene ID" value="DB41_EV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="245" mass="28859" checksum="C457905AEC5024FD" modified="2015-04-01" version="1">MTCFFNYYIVLENKNTEKLSLPQRNKMHPISSTSIESLPNELLLPILEACVVPSLFSVCKRWHHLLASEVMPSLYKQIGKVHVSQGDINKQAFILDRIYKLESRLSETAKVNAIFRQIFTSASSLSPLEFKWRTKEKKYFTLANYSSYLLNINRLLLWKKLPSGEEYLSREESKHSPLEFKWKTEEKKYFTLTNYFSYLLDINRLLLWKKLPGGEEYLGREEIKHLPLEKKESFLNIGLKEIVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIZ0</accession>
    <name>A0A0C1HIZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77234">
        <property type="protein sequence ID" value="KIC77234"/>
        <property type="gene ID" value="DB41_CO00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="5199" checksum="E3D5A2FE96CA5B56" modified="2015-04-01" version="1">MSAIQKWIRRYNQHQVEGLKDRRPVIAGRKRALTFEQEKAFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ09</accession>
    <name>A0A0C1HJ09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77254">
        <property type="protein sequence ID" value="KIC77254"/>
        <property type="gene ID" value="DB41_CO00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5495" checksum="5B78AFBB313E4D27" modified="2015-04-01" version="1">MLGYLMPSFHFTHPFKRLVSAGFYNQSQLEETGFFKFFASVGISADDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ19</accession>
    <name>A0A0C1HJ19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CO00330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383132.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77264">
        <property type="protein sequence ID" value="KIC77264"/>
        <property type="gene ID" value="DB41_CO00330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.67"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="571" mass="67908" checksum="A6B536D74359D092" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJS2</accession>
    <name>A0A0C1HJS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IF00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74758">
        <property type="protein sequence ID" value="KIC74758"/>
        <property type="gene ID" value="DB41_IF00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6577" checksum="A6E69F3B42AD1F78" modified="2015-04-01" version="1">MHTELEIFFSGIHLYFSCPQKVFENHEALQEMVFDLKLIGETFEIDQLDIQLTSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK98</accession>
    <name>A0A0C1HK98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphohydrolase</fullName>
            <ecNumber evidence="2">3.6.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mazG</name>
        <name evidence="2" type="ORF">DB41_IB00510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74918">
        <property type="protein sequence ID" value="KIC74918"/>
        <property type="gene ID" value="DB41_IB00510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1484"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047693">
        <property type="term" value="F:ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="26"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="221" mass="25293" checksum="FB4A0BF36EDF35FD" modified="2015-04-01" version="1">MQEFNQLIEIIERLLAPEGCPWDQAQTLHSLRPSVLEESCEVIEAIDLGNNSHIQEELGDLFFNAVFLCKIAEKEKRFTFGAVLNELNEKLIRRHPHVFGEGKKINTSQELSHQWEEIKKREKGKDTRKSVLDGISKCLPALSRAQKVLKKIKNFGYLKDLPAGDLSCIHNENELGKHLLFLVGVAQKQGLDAEHALRKTLAHLEKDFQLFEKKAFINNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN48</accession>
    <name>A0A0C1HN48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75763">
        <property type="protein sequence ID" value="KIC75763"/>
        <property type="gene ID" value="DB41_HG00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4516" checksum="6336744312CB33D5" modified="2015-04-01" version="1">MDFLASPHNALKHFIKKKPDKADRLKVFLIAGHSYYALM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNL2</accession>
    <name>A0A0C1HNL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GZ00520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385008.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75888">
        <property type="protein sequence ID" value="KIC75888"/>
        <property type="gene ID" value="DB41_GZ00520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="223"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="227"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="259"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="485"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="614" mass="69555" checksum="7DC8EB8EC73D80D3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPE0</accession>
    <name>A0A0C1HPE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GN00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384787.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76103">
        <property type="protein sequence ID" value="KIC76103"/>
        <property type="gene ID" value="DB41_GN00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007922">
        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05258">
        <property type="entry name" value="DciA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="112" mass="12742" checksum="8434E943ACE6B880" modified="2015-04-01" version="1">MQKAIRRTPKNYDGTAITTHKISDVLSQLVFQIRENYRHRPDLVLAAWPEVIGAKLASMTQAMSFIDGVLHVKVKNSTLHSLLSQNDKNRIIASLKTKFPHIHLKNIVFRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQK7</accession>
    <name>A0A0C1HQK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GB00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76468">
        <property type="protein sequence ID" value="KIC76468"/>
        <property type="gene ID" value="DB41_GB00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4356" checksum="865C86FFD883B6F0" modified="2015-04-01" version="1">MNAYLQRQHARSPLGEKIYGALAGRSFATESFIAAKWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQQ4</accession>
    <name>A0A0C1HQQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FX00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243859.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76508">
        <property type="protein sequence ID" value="KIC76508"/>
        <property type="gene ID" value="DB41_FX00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="103" mass="11770" checksum="A49F498B198F91A8" modified="2015-04-01" version="1">MHQHGKAKRRICRKIYLAICPDSHEIILRELIKSNKVDDSVASQMIFKLPKSVQTAYRDGAYDRQASCRSSYVRGIDPLVSPSRGGRLSQEADKPWIKKRKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQV0</accession>
    <name>A0A0C1HQV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FQ00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384307.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000078.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76543">
        <property type="protein sequence ID" value="KIC76543"/>
        <property type="gene ID" value="DB41_FQ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="553" mass="63600" checksum="A39527B60C7691A6" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQX9</accession>
    <name>A0A0C1HQX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76563">
        <property type="protein sequence ID" value="KIC76563"/>
        <property type="gene ID" value="DB41_FN00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6991" checksum="CDC695D2D6897EF6" modified="2015-04-01" version="1">MILTEDQLKALEKAREENEAHGEIVTEHLGYLLFQNNYYVGTIKVFRRIYQHTVIGHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRA5</accession>
    <name>A0A0C1HRA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_FD00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384086.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000066.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76653">
        <property type="protein sequence ID" value="KIC76653"/>
        <property type="gene ID" value="DB41_FD00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.653"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="128"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="202"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="249" mass="27520" checksum="6BEE7CB9882EC39E" modified="2015-04-01" version="1">MNRRDTIIIAVLLNAALLAILFMMAVRHEDPTDEFHNAPQIIMDANKQLTPSSQELINSPSDASISSTPTGDEIDNVLKHYADSPHLILVEEEGELGDKELSASLPTDRSESRQISPLEASTQPSQLVTITVKKGDALEKIARANNTSVEAIKKANHLTSNRLNIGQLLKIPVGTKKNHLDHGQQKPLAVKQTTPITSAGPELYTIKSGDNPWKIAKQFNVKFDDLLKMNNLDEEKARNLQVGDRIRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSJ1</accession>
    <name>A0A0C1HSJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein YuzA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yuzA</name>
        <name evidence="2" type="ORF">DB41_DL00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383478.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77033">
        <property type="protein sequence ID" value="KIC77033"/>
        <property type="gene ID" value="DB41_DL00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.280"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007211">
        <property type="entry name" value="DUF378"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37304">
        <property type="entry name" value="PTHR37304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04070">
        <property type="entry name" value="DUF378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7409" checksum="1FCDB02AB9A01167" modified="2015-04-01" version="1">MKTLDIVTAILLAVGGLNWGLVGLFDFNLVEFIFGQFPAIARLIYALVGGAAVYQLFQWKTLKQCCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT33</accession>
    <name>A0A0C1HT33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CP00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77228">
        <property type="protein sequence ID" value="KIC77228"/>
        <property type="gene ID" value="DB41_CP00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="5018" checksum="02C7F4D9659E06A3" modified="2015-04-01" version="1">MKMPLTSLSDLKSYPLSTEIDLKKFVLRFNLITAIYNWELKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JIY6</accession>
    <name>A0A0C1JIY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000233">
        <property type="protein sequence ID" value="KIC71340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71340">
        <property type="protein sequence ID" value="KIC71340"/>
        <property type="gene ID" value="DB41_BM00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="110" mass="12392" checksum="E4293105B9C92F53" modified="2015-04-01" version="1" fragment="single">MYPISSTSIESLPNELLLPILEACAVPSLFSVCKRWHHLLASEVMPSLYKQIGKVHVSQGDINKQAFILDRIYKLESRLSETAKVNAIFRQIFTLASSLSPLEFKGKTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJT5</accession>
    <name>A0A0C1JJT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UPF0159 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386934.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71590">
        <property type="protein sequence ID" value="KIC71590"/>
        <property type="gene ID" value="DB41_AV00300"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2268"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050797">
        <property type="term" value="F:thymidylate synthase (FAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003669">
        <property type="entry name" value="Thymidylate_synthase_ThyX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036098">
        <property type="entry name" value="Thymidylate_synthase_ThyX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34934">
        <property type="entry name" value="PTHR34934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02511">
        <property type="entry name" value="Thy1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69796">
        <property type="entry name" value="SSF69796"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51331">
        <property type="entry name" value="THYX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="548" mass="63133" checksum="ED81310A4BE7E0B4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKI4</accession>
    <name>A0A0C1JKI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AI00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386723.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71800">
        <property type="protein sequence ID" value="KIC71800"/>
        <property type="gene ID" value="DB41_AI00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="854" mass="99287" checksum="EFB2AE13B2065492" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL33</accession>
    <name>A0A0C1JL33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AB00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000202">
        <property type="protein sequence ID" value="KIC71995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71995">
        <property type="protein sequence ID" value="KIC71995"/>
        <property type="gene ID" value="DB41_AB00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2099"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="126" mass="14467" checksum="3437D427050463A0" modified="2015-04-01" version="1">MPAEIGRLSRLYTLELNQNQLASLPVEIGRLSQLQRLYLNQNQLTALPAEIGQLPQLEWLYLNQNQLTALPTEIGQLSQLTELELNQNQLTNLPKEIERLLDLRTLELAENPLKDIAEKISQRFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL68</accession>
    <name>A0A0C1JL68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72030">
        <property type="protein sequence ID" value="KIC72030"/>
        <property type="gene ID" value="DB41_AA00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="389" mass="45126" checksum="85DE76CAFEFEF18C" modified="2015-04-01" version="1">MKRKGLGKSLKINGRNLIKEGWMAEKFFSRLSYSFGNEDWRSEQEALKIKTGDRVLSITASGDRPLHLLLDDCEEIVSIDANPIQNHLLNLKCVAMQHLSYKEYIEFLGAVPARKQRLHTFQKLLPHFEEKSRHYWINKKKMIEKGVLYQGVVEKKCQSIVAPLLRILRGKKVDKLFEFSDLKEQQEFVKKAWDKVYWRKLFDLSLNSALARLLLRCIVSDPGLYNHLNGATRVGSYLYRRMHNSLMHNLAKESLLFSLIFKGKVAPEAFPPYLTQEGVSIIKKRTHRLKVKNIDVVTFLETSPANSFDCFSLSDVASYLSPKNFAKMMQEVLRVAKPQARFSIRQFLSNHQLPENLVSSFARDGELEDRLEKKDRCFVYRYMAGTISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLI2</accession>
    <name>A0A0C1JLI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KU00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72120">
        <property type="protein sequence ID" value="KIC72120"/>
        <property type="gene ID" value="DB41_KU00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="76" mass="8545" checksum="D36DB2C991A638E4" modified="2015-04-01" version="1">MSELTSSNEADDLIASQMCSKLPKSVKIVCGDGAYDRQAFYRSSYVRGIDPVVPTRRGGRPSQETDKPWMKKEMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLM1</accession>
    <name>A0A0C1JLM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_Tnp_IS630 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BB00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000222">
        <property type="protein sequence ID" value="KIC71471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71471">
        <property type="protein sequence ID" value="KIC71471"/>
        <property type="gene ID" value="DB41_BB00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002622">
        <property type="entry name" value="Transposase_14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01710">
        <property type="entry name" value="HTH_Tnp_IS630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_IS630" evidence="1">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6734" checksum="066C67AB5CF485C9" modified="2015-04-01" version="1">MATASHVFGVTVRTLTNWIKRKERGYLAPKKRRQSPSKIDSEKLKLYISQAPDAYLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMF0</accession>
    <name>A0A0C1JMF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AM00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244108.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000210.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71741">
        <property type="protein sequence ID" value="KIC71741"/>
        <property type="gene ID" value="DB41_AM00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="178" mass="18508" checksum="FB634D9FC2988459" modified="2015-04-01" version="1">MNKKDLKKLALLGITGGVMMASQGSVYADTSNHLATPGVLMASGCGAGTCGNQGKPSSGLNRESRIIAEADESLKSSSSTQLMTEDQLKSQLNEQGKENYNSLNAEGKALAQKLASRTCKGNNDCKGLNSCKTEEHSCAGKGSCAGSSACNFKDKNLAIKVAAQKQAEKRAQTNQGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNA4</accession>
    <name>A0A0C1JNA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Virulence plasmid protein pGP6-D-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AA00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0137 (pGP6-D) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386552.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72021">
        <property type="protein sequence ID" value="KIC72021"/>
        <property type="gene ID" value="DB41_AA00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2074"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005350">
        <property type="entry name" value="UPF0137"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03677">
        <property type="entry name" value="UPF0137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="248" mass="28235" checksum="DAD1A1B8B919BF07" modified="2015-04-01" version="1">MSHVNSLISERLKKNSQTSKMSALAKQSASGNLTSFSGIFSLSELNDKEKEFLLNLLRQYAVGKEDLEQDFTSLTSITSEVKAINNQAAILHGERIKKAQSILTRYKDGAFTAWLLAAYGNRQTPYNFLQYYEFYEQLPKKLRPQIEAMPRQAVYTLASREAPLEKKQNFVESYQGETKAELLIKIRELFPLEDKDKRGPNWGENTIQQLKKLTAILDQKNVSISKVHQSLICELLDNLKVVVSGRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNM3</accession>
    <name>A0A0C1JNM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KA00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000183">
        <property type="protein sequence ID" value="KIC72840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386261.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000183.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72840">
        <property type="protein sequence ID" value="KIC72840"/>
        <property type="gene ID" value="DB41_KA00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1845"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002147925" evidence="1">
        <location>
            <begin position="19"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="507" mass="55891" checksum="22AEF6ED0E635301" modified="2015-04-01" version="1">MKKILMFLLVIMAAYSHGYSQSCDHARGRTHNALIPTFKLALAPRPATEETAIAFFGEVGRRNYRANGTVGWLYSHEDRFKLSAEYLTQRLGYRFSTGKKERWMHQYALGAKYQHDFYHQFFNKVEATAYYSYAASHNLKPKRCKDFLYWRRIAGSSSYGGSLGITITPWYSSRFQVDADFDSVSYRRKYRSRKHLSGLGASFGYQQQIASHFLLDLLAEFKRHYNYGKVRLSWSQPEWTGLTVGLFGAHTRGKSHLPNLTTAGIELTYAFGTQKQMDNNACNPCYCDPALAGWVSAPAVYMPEVLAITEEKRKKMIVPPSCHELKYSPIPNFSFSGNEPYSFDISPYFSNPSGGALTYSASGLPAEASINPTTGLISGIGLQDNQIYNIVIMATASDACASVSQSFTISFPCAPPTSTPLENPINLAMLGGQPYTLDQVTGHFFSPNGEPFTFTATGLPSGSSINPTTGVITGISRGSGPVFAVTITGTTPCGSTSQSFVLTFYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPT3</accession>
    <name>A0A0C1JPT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KJ00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386371.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72531">
        <property type="protein sequence ID" value="KIC72531"/>
        <property type="gene ID" value="DB41_KJ00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021272">
        <property type="entry name" value="DUF2851"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11013">
        <property type="entry name" value="DUF2851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="435" mass="51074" checksum="6D1C479C95C2BDED" modified="2015-04-01" version="1">MHVSLYEEENDWYSNLLAINSYNVAETKYPYLYWTENHLQAMWWEQKYFKNLKTSDQLPITVISPGIWNHEAGPVFLNAHLKIGDQELRGDIEVHLEDEAWTNLQHDSDNRYKEVILHVCLWPPLSAAPTPIKNAKGEKVYQTYLAPYLTISQTRILQLIDIEQYPYRKFLGNNPSCFSPSSSFVEEKIFNLLPSSVSWGLAQKVQYLKGHMEDARLLLPTGIAMALGGKQNAEAFFELFVRLLKYKDKTENELLSIALGMSGFFAEKYKLKWKDSFFYQELLQIYTQFSTLIPHSIRLLLNQIRPLNHPIRGIAYLVKLIQDPLMPSLFTEIYACWHQGWPEAYLKKDWKLLLNRIKDRLPSYSDEYWRHHYTFESQKQALPIPLLKKSWKDKVILNTVLPLLSSEIIQKNNPSEIKAFHNFYSFLNRVKDDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JR89</accession>
    <name>A0A0C1JR89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JU00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000177">
        <property type="protein sequence ID" value="KIC73026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73026">
        <property type="protein sequence ID" value="KIC73026"/>
        <property type="gene ID" value="DB41_JU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="16667" checksum="EAEA77B9077184E5" modified="2015-04-01" version="1">MAIMKPISFLEQILSQVTFLYQYLLSNQHKEMDSRPEIKEAIQRLSRQIQEISHMTDTEASRMGISQEELRKTILESKDHLPPDIQNFLEKTQYLKSQLEGCRNVLKAATEKQKEERKNKQLGDKRKEKFNHVGGKKGWIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JST0</accession>
    <name>A0A0C1JST0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA polymerase I</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">polA</name>
        <name evidence="15" type="ORF">DB41_JH00070</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73546">
        <property type="protein sequence ID" value="KIC73546"/>
        <property type="gene ID" value="DB41_JH00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1749"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 11 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="13">
        <location>
            <begin position="2"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="12">
        <location>
            <begin position="305"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="14">
        <location>
            <begin position="652"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC73546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="894" mass="101615" checksum="7663D87995E61D25" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTM3</accession>
    <name>A0A0C1JTM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmF</name>
        <name evidence="6" type="ORF">DB41_IY00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386081.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73811">
        <property type="protein sequence ID" value="KIC73811"/>
        <property type="gene ID" value="DB41_IY00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1700"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC73811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6563" checksum="88285A1093CB2405" modified="2015-04-01" version="1">MAVPRNRHSNARKNSKRAHHAKKPKQLANCSNCQSPKLPHVVCPSCGQYNGRVVMARKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWG4</accession>
    <name>A0A0C1JWG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">LPG_synthase_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_IF00080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385887.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74761">
        <property type="protein sequence ID" value="KIC74761"/>
        <property type="gene ID" value="DB41_IF00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016732">
        <property type="entry name" value="UCP018688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41373">
        <property type="entry name" value="PTHR41373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="LPG_synthase_C" evidence="8">
        <location>
            <begin position="31"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="140"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="285" mass="33035" checksum="09E174953CBD96AE" modified="2015-04-01" version="1">MIIKPLTLEHQPLLSPAWRDLCVTYDLRFAEYSFANAFLFRKKYAYQFVECSTPCLQGRWQNNDCFVIPSVPPKQIKFKLSELLPGCTCCFFPLPDAWVEECQKMNMSLISCRADTDYLFRKSKLQTLQGRELSSRRNLLNQLERKYSLESKEIKEENIQEAFKLLERWQSQKEDSKETTDYYSCLEALTYISQLHLFGRIAYADGQAFGFTLGELLTPKTALLHFTKALTSIKGATPFLYRDFALSLPDSVQWINLEQDLGIPALRQAKNAYNPDLLLTKWKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWL1</accession>
    <name>A0A0C1JWL1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inorganic diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppa</name>
        <name evidence="6" type="ORF">DB41_HL00130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385332.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75480">
        <property type="protein sequence ID" value="KIC75480"/>
        <property type="gene ID" value="DB41_HL00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1272"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="24098" checksum="9BA3C2C12F2A3408" modified="2015-04-01" version="1">MANMIYRSHPWHGLSLGPLMPQIVNCYIEIVPTDTIKYELDKETGILKVDRPQKYSSVCPSLYGLLPKTYCGHHLASYCMQKTGLKNIQGDGDPLDICVFTEKVIPRGDIILKAIPIGGFRLIDGNEADDKIIAVMADDLVYGSLQNIDECPQSLIERLRHYFLTYKDFPEKTNGTVQITHLYDVKEAHQVIGLALQDYEDKYGSASKPENFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWQ7</accession>
    <name>A0A0C1JWQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-splicing ligase RtcB</fullName>
            <ecNumber evidence="4">6.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rtcB</name>
        <name evidence="4" type="ORF">DB41_AS00210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244123.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71667">
        <property type="protein sequence ID" value="KIC71667"/>
        <property type="gene ID" value="DB41_AS00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2224"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="206"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="319"/>
            <end position="320"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="355"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="379"/>
            <end position="382"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="469" mass="51211" checksum="4FD9D82476EE8381" modified="2015-04-01" version="1">MNPKEFQALLDQKIFTSSEKDKAWTLYKKESPQKALAFLKTIENKFGSIRRSLLLQPLPVPYKVWGENYIEAETIAQMDKAARLPVALAGALMPDAHLGYGLPIGGVLATENSVIPYAVGVDIACRMKLTIYPLPAHVLENPTSVEYKNLYSALLNNTVFGAGAAGIHKGKIDHPILEKSHWELSPLTRSLRQTAIYQIGTSGGGNHFVEWGELKIFETENPFKLAAGTYLALLSHSGSRGVGFKIADYYTKMAMAQLRELDHSVKHLAWLPLDHDLGREYWEAMQLAGQFASANHHVIHQRIAEAVGIAPIATVENHHNFAWREKIHVQGKEKEAIVHRKGSTPSGKGVLGIIPGTMADAGYVVVGKGNLDSLSSASHGSGRQMARTKAKKTISLEQHLNSLLKQGIDLIGGGLDESPQAYKPIEAVMKEQKDLVDVIGKFQPKIVRMAAEGSLSSLSSLPQGIVKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXJ9</accession>
    <name>A0A0C1JXJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="3">1.7.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">queF</name>
        <name evidence="3" type="ORF">DB41_AD00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000204">
        <property type="protein sequence ID" value="KIC71967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386632.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000204.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71967">
        <property type="protein sequence ID" value="KIC71967"/>
        <property type="gene ID" value="DB41_AD00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00817">
        <property type="entry name" value="QueF_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029139">
        <property type="entry name" value="QueF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016428">
        <property type="entry name" value="QueF_type2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14819">
        <property type="entry name" value="QueF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004750">
        <property type="entry name" value="Nitrile_oxidored_YqcD_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03138">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="QueF_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="275" mass="31920" checksum="F1F4810961F1F87D" modified="2015-04-01" version="1">MKDETLINSPLGKQTFYDTVYDPSLLCPLPRDKQRQAIGIADVNLPFQGYDVWNAYELSWLNVKGKPLLAIGEFFFPCQSPYIVESKSFKLYLNSFHQTTFANLEDVQAILEKDLAKCVGQPVKVNLIQSKDYASLCLKNLPGFCLDNLDIETNLYAVDPSILGHAAELVEEEFYSNLLKSNCPVTKQPDWASLYIHYIGPKINKESLLKYIISFRSHYEFGEHCIERIFMDLQKYCRCHKLTIYGRYTRRGGIDLNPFRSNFESFMRNIRDYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXR6</accession>
    <name>A0A0C1JXR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243920.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75865">
        <property type="protein sequence ID" value="KIC75865"/>
        <property type="gene ID" value="DB41_GZ00290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1094"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="38038" checksum="844ADAF3035039B4" modified="2015-04-01" version="1">MEERCFLQAGKLIRPFSLSSKVRCRGYSLPLERAITDFGADIAFGKVGEKMKEHYGIEASSSMVRLITQKHASKIAKLKKETSTQEAIIISETDGSMVPIVEINEADKQAKKDARKARKVCWKEAKLSLARGKDKANRFYAGSIGTAEQAGQQMLECALIAGLKEGSYVHAISDGAPWIAEQIKLKFCNRSGHLIDFYHLCGYLSEAAIWCNIFEPKKWLEESKEKLKAGKSREVFKEIENKFKALDHPEQENGLVRCYRYMEKRLDMMNYKSALDKGLPIGSGEIESSHRHVVQKRLKIAGAWWKTENANAMLSLRIGRLNGYWEAYWNSYKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXU8</accession>
    <name>A0A0C1JXU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein YacP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yacP</name>
        <name evidence="1" type="ORF">DB41_AA00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72032">
        <property type="protein sequence ID" value="KIC72032"/>
        <property type="gene ID" value="DB41_AA00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010298">
        <property type="entry name" value="DUF901"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34547">
        <property type="entry name" value="PTHR34547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05991">
        <property type="entry name" value="NYN_YacP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="207" mass="24152" checksum="F0D42B2D823EC72A" modified="2015-04-01" version="1">MHYFIDGYNLMFRVLKADNELQAQREAIIQDLNKKIHLLGLQATIIFDAHHQAGESSRTHLQQLEIIFTSAGETADERILQELIHSKNPRQETIITSDKKLAWLARRRNARTETVEDFLVWLNARYQKRLKYSTQQASPLEVKQKSILRFSSKKTLLSKPLTSVEGCFEFYHQQFEISFQSMVNAHSIKKKKGPIKQKEILKTLIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY66</accession>
    <name>A0A0C1JY66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386542.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72117">
        <property type="protein sequence ID" value="KIC72117"/>
        <property type="gene ID" value="DB41_KU00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="132" mass="15503" checksum="32053F25EBE148E4" modified="2015-04-01" version="1">MIIEQDLKKLFQKLDHDQVLHLEVNENELEIKVFDGASKIFLTTRIYNGDNFIPKSVRNGIARKAPWSRASIKTFLSVNENQYRVDLNYLGLLQQMNAQSFALLMEDFARLAYGWRVYLDEQDQNDLIHVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYS7</accession>
    <name>A0A0C1JYS7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sodium/proline symporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Proline permease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ycgO</name>
        <name evidence="9" type="ORF">DB41_HJ00010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the sodium-dependent uptake of extracellular L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28967"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75601">
        <property type="protein sequence ID" value="KIC75601"/>
        <property type="gene ID" value="DB41_HJ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1244"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005298">
        <property type="term" value="F:proline:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031402">
        <property type="term" value="F:sodium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015824">
        <property type="term" value="P:proline transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11475">
        <property type="entry name" value="SLC5sbd_PutP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011851">
        <property type="entry name" value="Na/Pro_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="499" mass="55262" checksum="3043B29A703F4DA5" modified="2015-04-01" version="1">MPILKAESIILKPTVERMHYFLVISFFAYFFMLLCMGLYFHKKQTSAADFIIGNRSLNFWLTALSAHASDMSAWLFMAFPAAVFSSGLPKIWIAWGLIGGMFVNWQFIATRLRRATEKYNAHTLSTFFERRFNDTSGTIRFLTAAIALFFLASYIAAGLIAMGLLFESVFGINYYVGLSVAMLVVVIYTLIGGFVTVAWTDLFQSLFLMAMIIFVPAYAFMHLPNGWQSITEAAKNQNASLFFFKDLSSSSILEAIFMATWGLGYFGQPHIVTKFMGIKNVEEMHKSKYVGMSWLILTLLGATAVGLIGLPFFDGQLRDPQLVFIDMVPLLFHPLVTGFILCAILAANMSTMDSQLLVCASIISEDFYKGIFKKEASAQKLLLISRLGLVFTALSSLILAYNKSTTVLEAVRYAWAGLGCSFGPLMLMSLYSQSINKYGAIAGILTGGMIAGTWEAYSKQLLGHNIPAEIPAFAVSLISIYLVSKWTARITVECNSKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ59</accession>
    <name>A0A0C1JZ59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76305">
        <property type="protein sequence ID" value="KIC76305"/>
        <property type="gene ID" value="DB41_GK00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="5856" checksum="58891F5317BE09D7" modified="2015-04-01" version="1">MQAAFRTKWLASFFIISIFFPSKPPHGGTIVYKRELSLKGTLNRSDQNGNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZR9</accession>
    <name>A0A0C1JZR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GB00050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243867.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000087.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76470">
        <property type="protein sequence ID" value="KIC76470"/>
        <property type="gene ID" value="DB41_GB00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.820"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="310" mass="35480" checksum="FBA4011546DA3F83" modified="2015-04-01" version="1">MNPNSSISIEHLPNEVLSSILEYCPTPALLRVCTRWRHLLATEVMPSLYKQIGKMHVPQGNVSEQAFILDRIYKLESGLPEIAKVNAIFKQIFTLASSLSPLELEFKWKTEEKRYLTLANYSSYLVNINRLLIWKEIPGGKEYLDQEEIKYLPLAKKGELFRDWIERHGKVITSLNLTEIGLTFLPAEIGQLSQLEVLHLNDSQLSSLPAEIGQLSLLQYLYLNNNPLTSLPAEIGQLSQLQYLFIQKNQLTTLPAEIGQLSQLQRLSLSNNRLTTLPAELEQLPEHLDINLKENPLESIPDEIKQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K010</accession>
    <name>A0A0C1K010_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FQ00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384308.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000078.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76545">
        <property type="protein sequence ID" value="KIC76545"/>
        <property type="gene ID" value="DB41_FQ00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="18461" checksum="3C2FB0DA1D9CAABA" modified="2015-04-01" version="1">MTASSLNGGSLVGLPDYKVNDLIREKIPENTFTSINVQTVTHPFIGNDAKINARKITLTRSNLSVGWEVARAIFLQLFNSGKARLRYRDDPRAVNGNLVASFLGRDPSLEDKDIARAEEELKVIYARCMTITLYISDDCNYLEADSLTEHRAVVNARNAAQKCILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K058</accession>
    <name>A0A0C1K058_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FK00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76585">
        <property type="protein sequence ID" value="KIC76585"/>
        <property type="gene ID" value="DB41_FK00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="146" mass="17049" checksum="D815C81026DD19CA" modified="2015-04-01" version="1">MGYYVSMDMLEKIKKIEALIASSKSEGEKHAATLAKNRILERHKQEPVEKPLEYTIHLGNEWKKKLFVALCNKFQIQTYRYKRQKRTTAMLRANPTFVNNTLWPEFNKYAALLEDLVQDIINDLINKIHDVKEEEVVIAGELTETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0H9</accession>
    <name>A0A0C1K0H9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384726.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76261">
        <property type="protein sequence ID" value="KIC76261"/>
        <property type="gene ID" value="DB41_GL00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025159">
        <property type="entry name" value="AbiEi_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13338">
        <property type="entry name" value="AbiEi_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="204" mass="23554" checksum="855E3D3E18420E6E" modified="2015-04-01" version="1">MKKKSKLELALAAFRKQGGILTMSEAIAIGIHRRELYTLRDRGDLEIVSRGLYRLVEMHAPSLPDFIPVAKKIPRGVICLISALAFHEITTQIPHFVYVALPSQTHKPAISYPPMRYFWYTEELLKTGVQEHAIDGCIFKIFDIEKTLVDCVKFRNKIGMYVVLEALKMYWHSRKTNLDKLFEYAKLFRVKKILKPIMETIVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K148</accession>
    <name>A0A0C1K148_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EC00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76860">
        <property type="protein sequence ID" value="KIC76860"/>
        <property type="gene ID" value="DB41_EC00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6836" checksum="7AD76FF4E9EAE67A" modified="2015-04-01" version="1">MTGAFSCHIERRALLKLKKRKEPYKAHASKLICNLSIGTMLAAILPSLYGRIRQRLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K172</accession>
    <name>A0A0C1K172_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76875">
        <property type="protein sequence ID" value="KIC76875"/>
        <property type="gene ID" value="DB41_EC00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="100" mass="11123" checksum="F333B48EBC82C8BF" modified="2015-04-01" version="1" fragment="single">MNDFRIPSFDPKAALLPQGKASFEQKKDPTVHIPSHRQAAMKGKESNFIKQMNNRAIKIINFVKSTFTRAEGQGGIKNSSVIKGGSRNIEKLARPWISGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1A9</accession>
    <name>A0A0C1K1A9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DW00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383690.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76900">
        <property type="protein sequence ID" value="KIC76900"/>
        <property type="gene ID" value="DB41_DW00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.417"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="422"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="674"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="758"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="800"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="842"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="884"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="943" mass="105583" checksum="93837E8BBCC3EA0A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1C1</accession>
    <name>A0A0C1K1C1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DT00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383646.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76910">
        <property type="protein sequence ID" value="KIC76910"/>
        <property type="gene ID" value="DB41_DT00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="149" mass="17318" checksum="8F9B68A35D5922D9" modified="2015-04-01" version="1">MTNYQTHHFIFHPGVWIGEGKITFSTSPESLHFYTKWVVDKQKENIGYICQQSVEIHGVDEQVSNQLTFFEMAPASFSVRLENELIGSVNGKGVIDAKIIAWEYPLSNDFEGFEVYELQENGDYFLRAEYNSSDQYRTIIEGKIWKKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1F9</accession>
    <name>A0A0C1K1F9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein YbeQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ybeQ</name>
        <name evidence="3" type="ORF">DB41_DQ00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76940">
        <property type="protein sequence ID" value="KIC76940"/>
        <property type="gene ID" value="DB41_DQ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="286" mass="33172" checksum="12B213FA4FC52745" modified="2015-04-01" version="1">MTFFSSIERSSAAPRASYFAKASFLMHPNVFLRPPHFGIQKISLDQPEFFHSILSLKDLVIKNHAMNLDYFIVLSQDEFQNIQVYDANLFLKYVWNDQLSSLTSPPKHFDRNFVIYRTNCAEENNELHYFCSREDLLDPRYIQYIKGHDIEANEEERQEAFISIAQGYAKGTGLFGQDYTQAFAWYERAAQFQHPLALCCLAIMKEDGQGTTLSLEQAFSYMHEAAKHNKRMQDPRINYMLARYYEKGIGTEKNPQKALKFYLKAAEKGFLDASQKVESLQTTNCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1J8</accession>
    <name>A0A0C1K1J8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hemB</name>
        <name evidence="13" type="ORF">DB41_JL00030</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="JRXI01000168">
        <property type="protein sequence ID" value="KIC73287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73287">
        <property type="protein sequence ID" value="KIC73287"/>
        <property type="gene ID" value="DB41_JL00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1775"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC73287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="341" mass="37948" checksum="3566650C002FAC01" modified="2015-04-01" version="1">MRPLLPDSLISSHHVDLAIRPRRNRKSPAIRSLIQENHLLPHQLVAPLFIIEGHQRQEMIASMPGICRISVDLLVKEATELYQLGIRAIDLFPVILEEKKDNLGKEAINPHNLLSRAIQALKQAIPEMCIIVDIALDPYTSHGHDGIVNESGHILNDPTLYMLGEMSILAAQAGADIVAPSDMMDGRVRYIRENLDKAGFKEVNILSYAAKYASSFYGPFREALHSAPKFGDKKTYQMDPANSREAILESILDEAEGADMLLIKPALAYLDIISIIREKTLLPLAAYHVSGEYAMIMAAAEKGWLDADKAFMESLLSIKRAGADFILTYASKRIARLIKMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Q0</accession>
    <name>A0A0C1K1Q0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_DN00110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76990">
        <property type="protein sequence ID" value="KIC76990"/>
        <property type="gene ID" value="DB41_DN00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="8">
        <location>
            <begin position="233"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="383" mass="44173" checksum="738E458120AAAF2E" modified="2015-04-01" version="1">MLLLILPNMPFSVFLKTSVNEYLKCLSLPDNLTVIHYVLGNESADLDSVISSLMYAYLLYENHSRQELYLPLINIKREEVNTRKDLLYLLQLAKISTNHLLFLEEAPFSYLFSRRQLRLNLVDHHILRMDQQIFSAAVESIIDHHFPEPINYPLLSPASLLIEPVGSTATLIAEKLFAHPTINITPKIATLLLAPILVDTHNLKSIDKTTWRDIKIAEKLLQVAAGALPSNFYDILQVEKNNISLLSPLQLLNKDFKSYLAGNFFYGISSLPQGVDWWQQERQSLLPLLNTYVQEKKLSLLILFMSPINPIGPKRRIIVYTPSPLILESFKFYVEKDVILKKLLMPSSLRHQCLAYYEIESFIARKHLQPYFHFLKNLANLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1W3</accession>
    <name>A0A0C1K1W3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384039.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76671">
        <property type="protein sequence ID" value="KIC76671"/>
        <property type="gene ID" value="DB41_FB00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="632" mass="71939" checksum="E791C6E4DA074D92" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1W5</accession>
    <name>A0A0C1K1W5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4277 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DL00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77035">
        <property type="protein sequence ID" value="KIC77035"/>
        <property type="gene ID" value="DB41_DL00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="1">
        <location>
            <begin position="2"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="21338" checksum="125D6319604D3A59" modified="2015-04-01" version="1" fragment="single">MTTGECIKLMVINELGFTSRPLYLEAQLYASKPVERLLGRACKSENISDDRLGRDLDRCYEYGCDAIFSAIALQACSKFNVNKKFQHLDTTSMSVQGQYFSEEQVPIITFGHSKDYRPDLKQFMISLICSQDGDVPLLAQALAGNTSDKSHFRKTLKELKSQIKDRSKPHYFVVDSAMYTAGTLKDPML</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K229</accession>
    <name>A0A0C1K229_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DF00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383399.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77075">
        <property type="protein sequence ID" value="KIC77075"/>
        <property type="gene ID" value="DB41_DF00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045738">
        <property type="entry name" value="DUF6088"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19570">
        <property type="entry name" value="DUF6088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="22641" checksum="58879259EB8622AF" modified="2015-04-01" version="1">MRQSIEIAVKNRIVEQGRGWCFTPMHFSDLGRDTSIRKALSQLQKQNIIRRLAQGVYDYPKIHDLLGTIPPDLNEVAKAIAEKNGVQIQPAGAHAANLVGLSLQVPGRVMFLTEGPSRKVKIGNQEIIFKKTTKKIMSSAGTREGLLIQALKNLGKDHIDQVARAQVSKFLKDSKENEIRQNMKFAPAWIRSLFFEIMGLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K266</accession>
    <name>A0A0C1K266_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EN00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000053">
        <property type="protein sequence ID" value="KIC76766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76766">
        <property type="protein sequence ID" value="KIC76766"/>
        <property type="gene ID" value="DB41_EN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="96" mass="10807" checksum="703323F3E16538B2" modified="2015-04-01" version="1">MAIGYNNLGQINKDQGNLVQAEEYSNKALAIDLELFGKYSPLVAFDYHDLGGIYKEQGYLEKAKEYINKTLAINLKLFGENHPIVTMLANKLKTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K275</accession>
    <name>A0A0C1K275_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">folE</name>
        <name evidence="7" type="ORF">DB41_EJ00060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383852.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76776">
        <property type="protein sequence ID" value="KIC76776"/>
        <property type="gene ID" value="DB41_EJ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.521"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="44"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="234" mass="26960" checksum="F880ACEA8A5AD881" modified="2015-04-01" version="1">MAKKAPKKQLSLRASAPLHIRTCYPSPILESIDDKTDEEKIKLIAEKYTEILQILGLDLSDDSLQDTPQRIARMYVKEIFSGLKDDNFPEVSFFENKYKPSKSENANIILVKVNFTSFCEHHFVPMRGYAYVAYIPHKKLIGLSKIPRIVRFFAKRPQVQERLAAQIVDSLAHLLETENVAISIIAEHYCVIARGIENEHSHTVTNILRGNFQNNEVVRREFFESIRIYNNTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2H7</accession>
    <name>A0A0C1K2H7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (cytidine/uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmL</name>
        <name evidence="4" type="ORF">DB41_EC00190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could methylate the ribose at the nucleotide 34 wobble position in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383740.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76871">
        <property type="protein sequence ID" value="KIC76871"/>
        <property type="gene ID" value="DB41_EC00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.446"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="151" mass="17358" checksum="37C37C454744A978" modified="2015-04-01" version="1">MKIVLYQPCIPQNTGNIVRTCAVTGNDLVLIPPLGFSISDRWLKRSALDYWEGVNVQLIENLEELLENSCYSFTFFSSKATRLHTEVNYQANDYLIFGSETKGLPPFFFQKWPERFVRIPMIEGVRCLNLATSVGIAVYEAWRQNHFKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2I7</accession>
    <name>A0A0C1K2I7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DZ00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383711.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76886">
        <property type="protein sequence ID" value="KIC76886"/>
        <property type="gene ID" value="DB41_DZ00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="150" mass="18023" checksum="8B0E3C3476A9284F" modified="2015-04-01" version="1">MGCFFFNFNPFNCIDLRPWRLITEAPPSIKTIPEEVIVHIFSFLSPKELVNAQQVCKHWKRIGNEETLWKRHHQQHFKDKPLHISFCLKKPRSFRNSYLFYNHRKSIRREVKLETASVRAHPDYNGRSFSELLLLMNQSQSFNHQKSLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2P3</accession>
    <name>A0A0C1K2P3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76976">
        <property type="protein sequence ID" value="KIC76976"/>
        <property type="gene ID" value="DB41_DP00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="9680" checksum="3E382E6999FE7894" modified="2015-04-01" version="1" fragment="single">KLKDDPVTAENYQKSLKKEDKIRFFLQEGFRKGAHSLLQACEDSEALPALLNVSSSNDLSSQEAVLSDRVETFKKLLKIVQKEFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2W7</accession>
    <name>A0A0C1K2W7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JB00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000159">
        <property type="protein sequence ID" value="KIC73677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73677">
        <property type="protein sequence ID" value="KIC73677"/>
        <property type="gene ID" value="DB41_JB00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1714"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="423" mass="48237" checksum="885C2603981E1CE1" modified="2015-04-01" version="1">MYINTSKKQLKIDIKLQRGYTMNPSSSLTIEHLPNEILTPILKACAAPSLYSVCTKWRHLLATEVMPSLYKQIGKMHVPHDDVYKQALIIDRIYKLEEDLSVAEKVNAIFKQIFALASPLSPLDLELKDKPKEKRYITLTNYCSYLVNINRLLMWEKLAGGEEYLGREEIKPLPLKEKGRLFKEWIENHGKDITRLDLRGISLKFLPTEIRCLSQLRMLYLNNNQLTALPGEIGQLSQLQELDLANNQLTTLPIEIGQLSQLQSLNLGGNQLTSLPGEIGQLLQLRELNLYNNQLTTLPIEIGQLLQLRDLNLNNNRLTTLPVEIGQLLQLRELNLNNNQLTNLPAEIGQLSQLQMLNLEYNQLTSLPAQIGQLSQLQWLDLPHNRLTTLPIEIGQLSQELGLDLNGNPLESIPEDIKQRFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K352</accession>
    <name>A0A0C1K352_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH_Tnp_IS630 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CX00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77141">
        <property type="protein sequence ID" value="KIC77141"/>
        <property type="gene ID" value="DB41_CX00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002622">
        <property type="entry name" value="Transposase_14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01710">
        <property type="entry name" value="HTH_Tnp_IS630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_IS630" evidence="2">
        <location>
            <begin position="4"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5789" checksum="0A59AC4ABBFDA9FD" modified="2015-04-01" version="1">MAPASHVFGVTVRTLTNWIKRKKQGYLAPKKRRQSPSKIDSEKLKWNLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K365</accession>
    <name>A0A0C1K365_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_CV00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383249.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77166">
        <property type="protein sequence ID" value="KIC77166"/>
        <property type="gene ID" value="DB41_CV00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.131"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020026">
        <property type="entry name" value="PseC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03588">
        <property type="entry name" value="PseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="392" mass="44205" checksum="84AB85E6A36808CB" modified="2015-04-01" version="1">MTKENFLPYTKPSINQIDIHEVTKALNSNHLTRGPLVEAFESAVAHYCQVKYAVAFSSGTSALMGAYFAANLRQQDSLLTTPNSFVATAGAAVQRGTTPVFLDIDCSSGNIDLQQLKYNLARPSSRGRICVAPVHFAGIPVDMQKIDQAIQNPETVVIEDAAHALGSTYFTGEKVGSCRWSDMTIFSFHAAKTITTGEGGMVTTNSEDFYRRLKLFRNNGIEREAPYLQGETAPWYYEVQHLSGNYNFTELQAALGLSQMARLDTFVEKRRQLMKAYRALLKEIPHLHLFAENFDAYTAYHLCVVQINFNAYKTTRTQVMNRLRERMIGTQVHYIPIYKHPYFINLCGDISDYFPKMEAYYSQALSLPLYYDLQLEEVEKVVNTLKTALQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5T0</accession>
    <name>A0A0C1K5T0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_II00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74617">
        <property type="protein sequence ID" value="KIC74617"/>
        <property type="gene ID" value="DB41_II00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1568"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="PTHR11802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="531" mass="60166" checksum="E3BC1B2277830F47" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6M0</accession>
    <name>A0A0C1K6M0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Virulence-associated protein I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">vapI</name>
        <name evidence="2" type="ORF">DB41_IB00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385706.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74892">
        <property type="protein sequence ID" value="KIC74892"/>
        <property type="gene ID" value="DB41_IB00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1457"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="16"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="102" mass="11465" checksum="06B833D62C71E67C" modified="2015-04-01" version="1">MLPKNRSPIHPGEVLLEEFLKPFKISQAQFASYLGGTWTQPKISEIISKKRGVTEAIALDFADALGTSPEFWLNLQNGYDLWFARQNHQPIPRIPALKAAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6N6</accession>
    <name>A0A0C1K6N6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Conserved membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_IB00400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385723.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74907">
        <property type="protein sequence ID" value="KIC74907"/>
        <property type="gene ID" value="DB41_IB00400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="7">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC74907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="414" mass="46938" checksum="A02BB4543F46FB3E" modified="2015-04-01" version="1">MNLSAGWWLFFNIFSIFVLAFFSMAEMACVSFNKIRLQYYYSKGHTRAIWLNDLLHNPSRLFGTTLIIVNLAMVIGSECARVFHQSIGLDPDLAPLSQVILVVIFGELAPILAARRYPEHIAMMGVPIVYFTAKLMTPILWVISGLSKLANYLIGGRESNANFYLSQKELQKLLEEQDDIKLHSSENKEFETITANIFKMNNKEARQLMIPIGQIPTIGATATILDAKRLMAKTKERFLTVHLGEMHHIIGIAFPRLLIRAADNKRLRDYCLPPWFITQNTNIMQILKQFKSNNQSVAVVLDVNGQASGILSLDCIMQAIFGPHHHPIHKQDALPNQLIIDRTLPGDMTIEEFYKQFDVKLADEKKLKLSELVLSKLGHMPEEGESIYIEPFVITVNEATLLEIKSVMITTLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6U0</accession>
    <name>A0A0C1K6U0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">pth</name>
        <name evidence="2" type="ORF">DB41_IB00850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385773.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74952">
        <property type="protein sequence ID" value="KIC74952"/>
        <property type="gene ID" value="DB41_IB00850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1520"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="190" mass="21405" checksum="139F9B6E5D496B7E" modified="2015-04-01" version="1">MHRLFVGLGNPGKKYELTRHNIGFMVLQELALNLGVQFKEKPQVQGWIAKTAWKETTIHLLMPTTYMNGSGQAVRRYMDYVKLVPDNLVVIVDDVALPYGHMRLRTEGGAGGHNGLKSIEAYLGTQRYARLRMGIGYHGMGSLADYVLDNFTPEEQKVLPTYVKQAVDVLKQLVNESITEVMKTVNKQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7H7</accession>
    <name>A0A0C1K7H7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385495.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75112">
        <property type="protein sequence ID" value="KIC75112"/>
        <property type="gene ID" value="DB41_HW00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="96" mass="10690" checksum="76D50033BC33FCC2" modified="2015-04-01" version="1">MTSITGSVFRSTAIESRGAASRVVERYAPLAVTNRKVNNLQALKLVLQESSSQTTRKLTQNYSKYVTDVNYDEFPTDVDYLNPSVEEAPKGKKTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K993</accession>
    <name>A0A0C1K993_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HH00200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243936.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75727">
        <property type="protein sequence ID" value="KIC75727"/>
        <property type="gene ID" value="DB41_HH00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134179" evidence="2">
        <location>
            <begin position="27"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="182" mass="20309" checksum="BA7D490D00199BCD" modified="2015-04-01" version="1">MYKSVLKTWIAPFLGVGALLSTHAFAQNAPLQTPPSTPVGLNDECSKELLISYFPKVFVLETLKKYNVPQDKWEAIASELAQKDKQVIKTVEEKAAKLDPNPLKDPQQRQAAVRLFRETLTDLFALTMKAHGIKDGKQITDMLNDIQQQKAKRFAMCMQKVSSEDSKGESKAENSATLGEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9C1</accession>
    <name>A0A0C1K9C1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ORF">DB41_HG00120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75757">
        <property type="protein sequence ID" value="KIC75757"/>
        <property type="gene ID" value="DB41_HG00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1183"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="173" mass="20009" checksum="9E76B55636419595" modified="2015-04-01" version="1">MHSLGLCVNKVAFNPLITFVQIHVYNKQKNLSFPLRLVKKIADAVIKLENQSCDELSIYFVTPLVISQLHQQYFNDPSTTDCISFPMDTNKHGEGPEKYRILGEIFVCPQTAFEYAKKHSGDPYEECTLYIVHGLLHLMGYEDTERKKKLIMRKAEKKHMVNLKKLNLLLLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9E3</accession>
    <name>A0A0C1K9E3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75797">
        <property type="protein sequence ID" value="KIC75797"/>
        <property type="gene ID" value="DB41_HE00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="11073" checksum="5E71CB37FBF2D1A9" modified="2015-04-01" version="1">MIKHNKKLGVKVCKYECLDILELRSKNFNQLPIIKYKTCLASPRFSTLKINVLKNSEEKACFFIEHILSFFRNLRKLNLLTFLGVNSDEERYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9Z1</accession>
    <name>A0A0C1K9Z1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GU00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384874.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75957">
        <property type="protein sequence ID" value="KIC75957"/>
        <property type="gene ID" value="DB41_GU00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="535" mass="59190" checksum="B405289436ABD977" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBI1</accession>
    <name>A0A0C1KBI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FX00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76502">
        <property type="protein sequence ID" value="KIC76502"/>
        <property type="gene ID" value="DB41_FX00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="401" mass="44298" checksum="EC977148813602C1" modified="2015-04-01" version="1">MCYCVGLNFGHNMAVRNISKLGSRAFHIYEGPAHQADKREKIGNFFYFFANVAFGKKIIFQKDGYSVKVRSLALRILAGMAAILCFKLTLIGRILIESSASHRLAFNTLVNMHISSANNLLPPKHNSSVDSYLSRSCANTVTQARSQKGLEGLKLEGLKKVNRLTLKKCRSLKPKSAVLNAPFVVTPQILSSVKLKPIQPGLSHASAKLSVNASLIPAQAPAKQITKSSCPISSLSVPYRETLKRTHSAVADSELSQKDLVAHKSVSMSDLLLNMSGAFWCKLSQLTEKNASSAGEEKSPIEESEWELSDDDQNGQFDYTELDREFINKNRSYNSSCSSKSSTSKNFHDALRKEEKTSNEDKLEKTSCQELLTSSLNSLRLAVAQDESESEEEEESLDFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC10</accession>
    <name>A0A0C1KC10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">rsfS</name>
        <name evidence="3" type="ORF">DB41_FH00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384129.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76637">
        <property type="protein sequence ID" value="KIC76637"/>
        <property type="gene ID" value="DB41_FH00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="121" mass="14051" checksum="98CD37FF270A55D3" modified="2015-04-01" version="1">MSKTVLKNLDLIAQTIYDKKGFNILALDVRDLSTMTDFYVIAEGNIDRHVRSIAKTIEEVMIQEGDELLHIEGIKAPDWLVMDYGEIIIHLFIPELREKYALEQLWQQAKIVDLHIDVKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDC9</accession>
    <name>A0A0C1KDC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000029">
        <property type="protein sequence ID" value="KIC77017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243773.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77017">
        <property type="protein sequence ID" value="KIC77017"/>
        <property type="gene ID" value="DB41_DM00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.285"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="16826" checksum="F34322C4741A6621" modified="2015-04-01" version="1">MQISPDSPSTPQSKKEQIIALFLKGVTEVDEIARLTGARPTYIGSLLQKEGLIKGYFDLYTSSQFFMNAYSKNFANRLGFKDSLSVQKSLRVLTRNYNKFKKSGDRAGQHHTLIMALTMFNRARWMGKNQEAKAFSQWLIEHLSLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H404</accession>
    <name>A0A0C1H404_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KP00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244066.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000195.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72269">
        <property type="protein sequence ID" value="KIC72269"/>
        <property type="gene ID" value="DB41_KP00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1994"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="391" mass="43527" checksum="4B3EAC98B3D63C25" modified="2015-04-01" version="1">MIPSSMNLELLPDEIQVHILKDCASPSLFGVCTRWQHLLANEVIPSLYKQIGKMRFPQRKATEQTNLLDKLYKLPAGLSTLAKVKEIFRQTYALAKSLAPSEFRGQIEEKKYFTLDNYTSLLLSINRLLIESRLPGYKKYLDRPDIKSLPLEKKEKLFAGWIKRYGKNIKKFELTGSELTALPPEIGGLSQLHELKLNDNHLFTLTAKIGKLFNLKELCLNGNHLTSLPAKIGQLSQLQELFLGSNKLTTLPAAIGQLSKLRGLYLNDNQLTILPAEIGNLSHLQELFLGGNKLATLPSTIGQLSKLQALYLNDNQLTMLPEEIGQLSQLQELFLGGNKLATLPSGIGLLSQLRLLYLSNNQLTVLPASLKQLPAGIDLNLDGNLLESISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA93</accession>
    <name>A0A0C1HA93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UPF0276 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AM00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71743">
        <property type="protein sequence ID" value="KIC71743"/>
        <property type="gene ID" value="DB41_AM00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2177"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007801">
        <property type="entry name" value="UPF0276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42194">
        <property type="entry name" value="PTHR42194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05114">
        <property type="entry name" value="DUF692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="294" mass="34220" checksum="A99A74B8E67165C9" modified="2015-04-01" version="1">MAMKNANIPNLGIGIGLRHVHYEDIFRLQPEIDWFEIISENFMVEGGKPLENLEKILAKYQVVQHGVALGIGSADPLDYNYLKKLKALTRLTKTPWLSDHLCWGHLPGAHYHDLLPLPYTQEVINYVAERARIVQDYLEIPFALENLSSYVAFQEDEMPEWEFYTAVVEKANIFMMLDVNNIYVSSRNHGFDAQKYIQNLPYDRVLQIHLAGHSDHGDYVLDTHDNYVRDEVWDLYADIYPRTGGVSTLLEWDDNFLSFQETWDEALKAKKFQKYLHDKASLERPMRQLQGVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAF4</accession>
    <name>A0A0C1HAF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein soc-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">soc-2_3</name>
        <name evidence="3" type="ORF">DB41_AF00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71818">
        <property type="protein sequence ID" value="KIC71818"/>
        <property type="gene ID" value="DB41_AF00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2146"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="611" mass="68510" checksum="3DF4908CA32414B9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC63</accession>
    <name>A0A0C1HC63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KN00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000193">
        <property type="protein sequence ID" value="KIC72383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72383">
        <property type="protein sequence ID" value="KIC72383"/>
        <property type="gene ID" value="DB41_KN00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="81" mass="9145" checksum="F2C73DCEB63ECAE7" modified="2015-04-01" version="1">MIRPFSLTSKVRCRGCFLPLERAITDFGADIAFRKLGEKMKEHYGIEASSSMVRLITQKHASKIAKLKKEASSQEAIIFPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCH3</accession>
    <name>A0A0C1HCH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KK00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244054.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72478">
        <property type="protein sequence ID" value="KIC72478"/>
        <property type="gene ID" value="DB41_KK00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1938"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="400" mass="45278" checksum="03DB53E0700EF2D0" modified="2015-04-01" version="1">MHPISSASIESLPNELLLPILEACVVPSLFSVCKRWHHLLASEVMLPLYKQIGKVHVPQGNVKEQALIVDRIYKLEEKLSETAKVNAIFRQIFTLAKSLSTLEFKVQIEEKRYLTLANYSSYLVNINRLLLWKNLRGGEEYLSREEIKHLPLEKKGELLREWIEENCKNITSLDLSRSGLIYLSSEIGQLSQLKTLELNESQLTALPAEIGQLSQLQMLDLRENQLTSLPVEIGQLSNLRHLYLNQNQLSSLPTELGQLTQLRELCLSQNQLTALPVGIGQLSELQGLDLNQNQLTSLPTEIGQLSQLQTLNLSQNQLTALPAEIGQLPQLQWLDLIQNQLTSLPVEIGQLSELQWLYLNQNQLTSLPAEIGQLSQLTKLGLAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD11</accession>
    <name>A0A0C1HD11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HS00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75309">
        <property type="protein sequence ID" value="KIC75309"/>
        <property type="gene ID" value="DB41_HS00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="6135" checksum="375C360A28436F08" modified="2015-04-01" version="1">MKNYLRGHLTEKLFLICNSSDQKKSFTLYCESLEQSLIFALIFARLILYCID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDH2</accession>
    <name>A0A0C1HDH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">lrrC1_9</name>
        <name evidence="4" type="ORF">DB41_KC00080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72818">
        <property type="protein sequence ID" value="KIC72818"/>
        <property type="gene ID" value="DB41_KC00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1858"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="12"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="447" mass="50042" checksum="C6E1428E85A30A5F" modified="2015-04-01" version="1">MYKGHTVNASSSITLEQLPNEILVPILKHCTSPALFSVCRRWHHLLANEVMPSLYRQIGSIHVPQGDISKQSLIVDKIYKLEGGLSETEKVKEIFKQTFALASSLSPMELEFKWVTEEKRYFTLANYSSYLININRLLIWRSLPGGKEYLEQEKIKYLPLANKGKLFKDWIENHGKGITEANLEGSGLTLLPPEIRQFSQLGRLSLGSNQLTTLPAEIGQLSHLQCLGLQHNQLTALPAEIGQLPQLKDIFLSGNQLTSLPAEIGQLSQLENFYLDNNQLTSLPIEIGRLSQLQYLGLQQNRLAALPAEIGGLSQLCTLHLDYNQLTTLPAEIGQLSKLEMLYLSENQLAFLPPEIWQLSSLYHLAISSNQLTTLPAEIGRLSQLEGLQLDDNQLTTLPAEIGQLSQLKVLLIGNNPLTSLPAEIAQLPEYLYLALEQTLRQILQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDL4</accession>
    <name>A0A0C1HDL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Skp-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HK00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000121">
        <property type="protein sequence ID" value="KIC75509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385310.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000121.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75509">
        <property type="protein sequence ID" value="KIC75509"/>
        <property type="gene ID" value="DB41_HK00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1253"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133194" evidence="3">
        <location>
            <begin position="27"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="198" mass="22229" checksum="8E36A87C42024765" modified="2015-04-01" version="1">MKKLSKKILQAASVSFALVALCPAAAEASAAKADQGIKMRLVNFKTCVEKSKLGKQEQASFESLKKQMETMLGEKEKTLNEMADKLNDPDYLDSLSPEAETELKRKFRTLSQEASQQQSQYYQAIQQANYKILDKLADVITQASETVAKKYGYHMVMNEEGAYYYDKELDISDDIVSVMDELFDKEAKEPKTPTGSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEM6</accession>
    <name>A0A0C1HEM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75894">
        <property type="protein sequence ID" value="KIC75894"/>
        <property type="gene ID" value="DB41_GZ00580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="149" mass="17706" checksum="D86A83635F1A91EE" modified="2015-04-01" version="1">MGGLMPKTNFTKVEESLIQGLDKLNIKKIIDSTSKDINEKRALDETRINKRKTAIYMISELKRLHKNDERIYLKLGTNLSHIKKMLEHPLKLNAEEWRNVLKLLDKIEAYKRAFAQTIKEVNNEEMVEKERKKQSDKRFNIQEKWLPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HER8</accession>
    <name>A0A0C1HER8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_GW00060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384919.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75934">
        <property type="protein sequence ID" value="KIC75934"/>
        <property type="gene ID" value="DB41_GW00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022781">
        <property type="entry name" value="Flagellar_biosynth_FliO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04347">
        <property type="entry name" value="FliO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="207" mass="23471" checksum="8E8A7C752261AC2C" modified="2015-04-01" version="1">MQKYIEMLELQLLISNPSDLMKNNFLCFVIVCTAYILCKQGYSEQAFDHPQTLAHFSPTLEEDHSDTLEKNQSENFETPIHSAHPTSKVEFSPKIDDNEGARFFHELINMLTTLGLIVAVVLIASWIIKRLLRGKIHQLNATSLIKVIEYRSLTPKTAVYLLEIKGKGIIIAESVNGVTHLGAFENNESEESLPLSFKERIENKDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFE4</accession>
    <name>A0A0C1HFE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">dnaA1</name>
        <name evidence="9" type="synonym">dnaA</name>
        <name evidence="14" type="ORF">DB41_GN00190</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9 10">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384795.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76109">
        <property type="protein sequence ID" value="KIC76109"/>
        <property type="gene ID" value="DB41_GN00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.980"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="143"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="360"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="151"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="457" mass="51815" checksum="9B5D119480476A63" modified="2015-04-01" version="1">MHAWNEFLALQEIELGSETVHKWLKSLKIIRFDAANLYLEAKDSFQALWFEEHMRQKILTKFVNNNNKKIKVHLSVANSLPRKAKSSSLKSAALSSHAPFTLCFDELDPYCTFEHYVSSEKNILVEKLLLSLAHSGPSKGLGTFNPIFIHGSSGVGKTHLLMATAQALRSQGLHVLYSRAETFTEHVVSAIRVGEMSIFRQAYRNSDVLIIDGVQEFSKKGATQEEFFHTFNTLHLDNKQIILSANCSPAELTYIEPRLVSRFEWGVVLNLFPLSREELALAIRKKAQFFNFPLHAKIIEFLLDNFPSSSKALIRALEALVLRSHLNEQMAKHSTVGITVPIAKQILSDLLIEEKQYVLTPDKIIKSIAEIFGIKSEDILGKAQSRDCVFPRQLAMYLCRQTLQMPFTKIGDIFSKDHSTVMSSVRLIKKGMEMNDKDIISAYQSIQKKIDFNEPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFE8</accession>
    <name>A0A0C1HFE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GN00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384803.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76114">
        <property type="protein sequence ID" value="KIC76114"/>
        <property type="gene ID" value="DB41_GN00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="488" mass="54934" checksum="EB7F11DE7DCBD2A3" modified="2015-04-01" version="1">MNFQAINAADINLVLRQLRYPEASNKNVLHPKPLSHQMCRGITYVGTAMQQHANSRRWHGKIIVVLSKSFVATGYLLNTPMAIIEGLVTAALAAIALAGHILLNARSPLFQKITLKLCAHSLNSALITDLQVTCLKQGFFSKYHSLNAAASHAIHGISALIPQLIGHTFDRQAGRLPTDGSLAPSVVKAIRIALEIAPAALQDISRGLARDFSSSIRNNLYDNITLEIFLRQNPDCIDMLNRLNFESLRDIHYRLRLLNLVGSYLMQASLLEGYQNTPHIYRYNVNTHAKDIKYQTHILYLIKAAFIDLYDNKELVCLLSKEKDKVKAIEDGRELLETLYNINLQLANYAQLQELHGEIVCPLQFRAVDLKPYNARYQRLVHAKNCLNQLSSEEQAILMKKLLQLGSYDIEKQGLSKKRAKFVQQLFNEIGTLSGELHQGNLLSRTFVDVNILNQGDVYRAFGAENLFVQACQKAIQEIQERTQKNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG56</accession>
    <name>A0A0C1HG56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lolD</name>
        <name evidence="5" type="ORF">DB41_GH00020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000093">
        <property type="protein sequence ID" value="KIC76364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384634.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000093.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76364">
        <property type="protein sequence ID" value="KIC76364"/>
        <property type="gene ID" value="DB41_GH00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.901"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="230" mass="25545" checksum="593A498717E72FB0" modified="2015-04-01" version="1">MEEIILQACEISKAYHYPAKVSILNNINLVVKRGETVAITGRSGEGKSTLLQILGTLEKPSSGQLAIAGQTINPFNCRKIRNQHIAFIFQSFHLLEDYTALENILMPARIARKSIAQGSKAYQRACSLLERVGLEDRAYFDTKLLSGGEKQRIAIARALCNDPDIIFADEPSGNLDKQTAQDIHQLLLDFASEKDKAIIIVTHDDKLSNLCNKKYLLEEGVLKLNSSSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGH8</accession>
    <name>A0A0C1HGH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GC00310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243874.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76464">
        <property type="protein sequence ID" value="KIC76464"/>
        <property type="gene ID" value="DB41_GC00310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="97" mass="11187" checksum="1F7213B42205B4E4" modified="2015-04-01" version="1">MKLDLLDIYTDYLISQNQQATVTGLSNLLDGQISHDKIIRFLNNNPGGSKEFWQYVKKQVRHLEQDKVGKLFPTACKSGANTKEKWWRKNLGNTYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGQ2</accession>
    <name>A0A0C1HGQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DB41_FW00020</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000083">
        <property type="protein sequence ID" value="KIC76514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76514">
        <property type="protein sequence ID" value="KIC76514"/>
        <property type="gene ID" value="DB41_FW00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="12">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="DUF294" evidence="13">
        <location>
            <begin position="191"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="590"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="632"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="674"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="716"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="758"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="800"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="842"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="884" mass="101647" checksum="2E3310C327987911" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHB7</accession>
    <name>A0A0C1HHB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383972.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76694">
        <property type="protein sequence ID" value="KIC76694"/>
        <property type="gene ID" value="DB41_EY00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="260" mass="30578" checksum="4A1BF2F77843A51B" modified="2015-04-01" version="1">MPITKPEDGVIVGTCHRLEWMLPWWWTHFRQHNEHPVLFVDYGDMSLQAKNWCQQRGELIKLELTDNFMAKKEQIDPMQACLWEKMQPQVWDLRFTWYKKPFALLLSPFERSLWLDLDCQVRGSLQPLFEWCVNEAGFAVAAEHALSQELNLHRKIITPGQIMYNAGVIAFAKHSKIIKEWVALAVEQNHLFCSDQQLMAHILNSHQGSFTTLPAIYNWTADQKFFSEVVILHRWGDEGKRNIAKIMELLTQEMNFNFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHQ7</accession>
    <name>A0A0C1HHQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative 16S rRNA m5C967 SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmB</name>
        <name evidence="6" type="ORF">DB41_EG00090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383768.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000046.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76844">
        <property type="protein sequence ID" value="KIC76844"/>
        <property type="gene ID" value="DB41_EG00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.466"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="119"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="375" mass="42740" checksum="D5D8862646F5F515" modified="2015-04-01" version="1">MKQSFRAYHLLQLLSAYDEQNLPLDAFINSYFRSHKALGSKDRAFIAENAYFLIRWIRLIDYLIQESPDWNKRVALLPYFDWQSHQNNPSIPAAIRVSFPDSLYNILVESYGALRASELCLISNTPAPTTIRANTLKATRDKLLELLQDKYEVSSCLASSHAINFLQRINFLAIPEFQAGLFEVQDEGSQLLANLVQCQPGQLVMDFCAGSGGKTLALAPSMQNKGQIFLHDIRSYALQQAKKRLKRAGIHNGQIMQANDPKLKKLKKKMDWVLVDAPCSGTGTLRRNPDMKWRFEIEGLKMLIGQQRTIFEKALSFMKPDGRIIYGTCSLLSQENEYQLKHFIKSYHLKVENQIFQSFPSLGGMDGFFGVVLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI07</accession>
    <name>A0A0C1HI07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase_M48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_IR00080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74238">
        <property type="protein sequence ID" value="KIC74238"/>
        <property type="gene ID" value="DB41_IR00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1669"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="208"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="449" mass="52039" checksum="9CE45799263BD64D" modified="2015-04-01" version="1">MFTHIFFLILALLLMNSLPETSAPAVHSAWSAFGISLLLYIGLCSTFFFQYPFLKKLFKRKPSFILFIINIELLAYLSVYQYLLDAGRLFHRIPFMQNMHFPNILWELSLYLGGLGLFYALSFVKFYSYSISETRFYYAQRQLQLLIPFFLPFVIITLVLDIFNALVSSQVTAKTLEWMSASFSLFIAILLFIFLPYFLQIIWKCKPLPAGTLNNRLTMICQKSGFKHAGMKTWTVMHDQLTAGIMGVISPFRYVMFTERLLKELSTESIEAILAHEIGHNTHRHLLFYPFILGGIIPLTGLFFYFFSAPLSYILAQEKAWPLSVAGNFFHTLKIFSFYALITLSYFRGVFGFFSRLFERQADLHVFKVGLPLESMIKALEAVAYANGDYATPNWHHYSIKERVEFLKSCLLNPLLIEQHHRKVKKALLIYFALFATALTFLLYLMINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI82</accession>
    <name>A0A0C1HI82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76999">
        <property type="protein sequence ID" value="KIC76999"/>
        <property type="gene ID" value="DB41_DN00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4955" checksum="B1D45124319E4125" modified="2015-04-01" version="1">MKERLSKYRKLTGGDQESCLLIFSSQIKTFLLYLKKAKDFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIE1</accession>
    <name>A0A0C1HIE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase, PAP2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DL00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77034">
        <property type="protein sequence ID" value="KIC77034"/>
        <property type="gene ID" value="DB41_DL00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="64"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="168" mass="18125" checksum="3275C1CB2C76741E" modified="2015-04-01" version="1">MDVYSNVGYFKSTNGVQPTMISSYLPTITPCQRSWIAAYTDIGQVALPVISGGYALFKKDYKGFGWLALSTLITQICLEILKRIVPEKRPTGSSRSFPSGNTAAAFLGPAFLVIRYGHSILSPAVAFSYLATIGVAIGRVLIKVHWPHDVLAGAALASTISYLTIPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIH7</accession>
    <name>A0A0C1HIH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="16">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16 18" type="primary">murB</name>
        <name evidence="18" type="ORF">DB41_DH00120</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the MurB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="16"/>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383430.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77064">
        <property type="protein sequence ID" value="KIC77064"/>
        <property type="gene ID" value="DB41_DH00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.247"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 16" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 16" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15 16" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0274">FAD</keyword>
    <keyword evidence="8 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 16" id="KW-0521">NADP</keyword>
    <keyword evidence="13 16 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="17">
        <location>
            <begin position="23"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KIC77064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="296" mass="32880" checksum="E1750DA3B08B1083" modified="2015-04-01" version="1">MNDDKLSSKLQNNKLLKSVCTFGIGGAAQYYREVHTIEEMQATLIYCHTRRLPFFILGKGSNCLFDDRGFAGLVIHNKIDFKHQQPEGIFHVGAGYNFSLLGSQTAREGWSGLEFASGIPGSVGGAVYMNAGANGKETHDSLKSVDFINQQGELKTFCKEELTYAYRTSIFQSMRGAIVGATFQLNPSAQARQKQIEIISYRKQTQPYSNKSAGCIFRNPDCHYAGALIEKAGLKGIQLGGAKVSEIHANFIVNTDNATSQEVLKLIEHIKEQVKIHCKIELESEVRYIPYEVERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIW6</accession>
    <name>A0A0C1HIW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">radA</name>
        <name evidence="8" type="ORF">DB41_CR00030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383186.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77209">
        <property type="protein sequence ID" value="KIC77209"/>
        <property type="gene ID" value="DB41_CR00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.95"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01121">
        <property type="entry name" value="Sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="68"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="353"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="254"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="97"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC77209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="458" mass="50563" checksum="6CA6F0EAC31EFAFB" modified="2015-04-01" version="1">MAAKQKSAWYCSECGHKQYKWTGQCPQCTSWNSMHEEVEVVGAKTRFEAQQPIRTSKPVRLKEVSHKGTPRIRTLLHEFDRLIGGGLVPGSLSLVGGDPGIGKSTLLLQISQALAMQGSIILYVCGEESVEQTSMRAQRLGIDSENLFLLSETNFSAIKAHIDQVKPDILIIDSIQIVYKGEISSAPGSVSQVRETTTEFMHIAKGHQIATFLIGHVTKSGEIAGPRVLEHLVDTVLYFEGDKQNNYRMIRVVKNRFGPTDEIAVFQMQQAGLVEVPNPSQVFLEERRKEAIGSVIIPTIEGTRAILIETQALVTETFFSTPSRRCTGIDQNRLALLLAVLEKRMGYQLHRCDVFVSIAGGMRITEPGIDLGVLLSVASSMRNLQVDAETTVVGEVGLGGEIRSVTRIESRLKEAIHMGFQHCLIPKRNIKGIPPEISQKIGIIGVEFVEEAVQQLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ41</accession>
    <name>A0A0C1HJ41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein YtfP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ytfP</name>
        <name evidence="1" type="ORF">DB41_IJ00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243989.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74543">
        <property type="protein sequence ID" value="KIC74543"/>
        <property type="gene ID" value="DB41_IJ00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1595"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="414" mass="45338" checksum="41DC9B5978858C56" modified="2015-04-01" version="1">MPKNLNTNHIKDYLVVVGGGAAGFFGAIACAQACIAKKVILLEKNRQLLSKVRISGGGRCNVTHACFDPVALVKNYPRGSQALLGPFTRFQPRDTIQWFKDRHVELKVEEDGRLFPLTDDSATIIDCLMRAAKAAHVEIRTESGIEKIEVQSAGFVIHLTNGLVVECKKLLFATGSNSKMYELLAALGHQIVPPVPSLFTFNVPNSPLLDLVGMSISNVGLRIQHTDLKQTGPLLLTHWGFSGPAVLKLSAWGARILHGMNYQATLVVNWLPEMNKETLAACLGNYKVKNPAKLISSDSPVALPKNLWKKLTIMAGIPYDMRCSYLSKVHLNALLELLQNSTFNIQGKTIFKEEFVTCGGVHLDDVNFKTMESKKCPGLFFAGEVLDIDGVTGGFNFQNAWTTGWIAGQAMAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK54</accession>
    <name>A0A0C1HK54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385696.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74883">
        <property type="protein sequence ID" value="KIC74883"/>
        <property type="gene ID" value="DB41_IB00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="10295" checksum="D0F05E983ABE97C1" modified="2015-04-01" version="1">MDLDQLNSIREQLNEWINVFKVYLGRSERVYWCRLYISGLILDGERKSIEPMAKRLPYCIHFRKKNCELFVSADLKKQKFKKFCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKD0</accession>
    <name>A0A0C1HKD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved putative membrane-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385760.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74943">
        <property type="protein sequence ID" value="KIC74943"/>
        <property type="gene ID" value="DB41_IB00760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="136" mass="15847" checksum="0C6B234BE50CC0CD" modified="2015-04-01" version="1">MDKHLIFYDGTCGLCSHVVYFLIKHDTKQQLLFAPLQGLTAKKLLGTLPRKVQTANSLILLKNYTSSQKEVYSLGQAALQVLWLLGGRWRLIGWISFLPSFLYNWVYRLIAQNRQRFFLQNSCLIPKEQDKNRFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKD6</accession>
    <name>A0A0C1HKD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="8">CMK</shortName>
            <ecNumber evidence="2 8">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">ispE</name>
        <name evidence="10" type="ORF">DB41_IB00810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 8"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243979.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74948">
        <property type="protein sequence ID" value="KIC74948"/>
        <property type="gene ID" value="DB41_IB00810"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1517"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="9">
        <location>
            <begin position="84"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="281" mass="31275" checksum="671ADB819B855DA8" modified="2015-04-01" version="1">MLTLLAPAKINLFLGVLNRRSDGYHNLASLIQTISLHDTLHFALGSQDVLMCEHPSLPKDSSNLITAATHLFRKKTGLNFGLKVVLEKNIPMQSGLGGGSSNAATTLWALNQLHGFPVPLEQLIEWSSEIGSDVPFFLSQGTAYCTGRGEVVRCLNPLPIQRLWIAKPYEGLSTPLVFKQLDLTKISSYDPELALQSFFSNQPFYFNDLEEPAFELKPYLKTVKEELLKSGYETVSMTGSGTAFYCLGRVAPPIIPQVIFYPATFINRPAERWYPFDSARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKF5</accession>
    <name>A0A0C1HKF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease P protein component</fullName>
            <shortName evidence="6">RNase P protein</shortName>
            <shortName evidence="6">RNaseP protein</shortName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">rnpA</name>
        <name evidence="7" type="ORF">DB41_IB00960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74963">
        <property type="protein sequence ID" value="KIC74963"/>
        <property type="gene ID" value="DB41_IB00960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="117" mass="13961" checksum="4912FAAEA3B69F45" modified="2015-04-01" version="1">MKYSFSKLFRLRKRYQFQKFTHSSKRLIGRWITIEILPSPLQMTRLGITVTKRYGKAHDRNRFKRITREAFRYCQSSLPLGQDLNVKPRVNAKQATSLDIYMDLMKLLSTNHHERGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLV7</accession>
    <name>A0A0C1HLV7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="9">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycogen branching enzyme</fullName>
            <shortName evidence="9">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">glgB</name>
        <name evidence="12" type="ORF">DB41_HN00150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75383">
        <property type="protein sequence ID" value="KIC75383"/>
        <property type="gene ID" value="DB41_HN00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1293"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="248"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC75383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="723" mass="84388" checksum="D3DB7697FF18757D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMU3</accession>
    <name>A0A0C1HMU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_HI00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75653">
        <property type="protein sequence ID" value="KIC75653"/>
        <property type="gene ID" value="DB41_HI00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="228"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="127"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="649" mass="73051" checksum="E19F2EFB280093E9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN24</accession>
    <name>A0A0C1HN24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_3</name>
        <name evidence="3" type="ORF">DB41_HH00360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243939.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75743">
        <property type="protein sequence ID" value="KIC75743"/>
        <property type="gene ID" value="DB41_HH00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="32"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="27"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="754" mass="84210" checksum="DA8BB966B8CB7561" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPG0</accession>
    <name>A0A0C1HPG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GM00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000098">
        <property type="protein sequence ID" value="KIC76123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76123">
        <property type="protein sequence ID" value="KIC76123"/>
        <property type="gene ID" value="DB41_GM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_5" evidence="1">
        <location>
            <begin position="7"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="273" mass="31759" checksum="98B767627148554B" modified="2015-04-01" version="1" fragment="single">MKLDLLDIYTDYLISQNQQATATGLSNLLDGQISHDKITRFLNNNSGGSKELWQYVKKQVRHLEQDKGGVLIIDDTIEEKPYTDENEIVCWHFSHTQGRCVKGINLLSCLISYGDYTFPIGFEVIKKDMHFCDVKTKKEKRQSSITKNQHFRALIQQAVTNQVKFEYVLADNWFGAKDNMEFIHYELKKKFIFGIKSNRLIAFSEEQRKKGQYQNLNTFNFKDGDKRIVWLKELAFPVALITKIFKNEDGSTGILHIVTNDLNHDSDPIYEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQC5</accession>
    <name>A0A0C1HQC5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">kdsB</name>
        <name evidence="3" type="ORF">DB41_GG00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384606.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76398">
        <property type="protein sequence ID" value="KIC76398"/>
        <property type="gene ID" value="DB41_GG00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.890"/>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="259" mass="28702" checksum="389D54D3C1681644" modified="2015-04-01" version="1">MSETKLPKIIGIIPARYGSTRFPGKPLATILGKSLIQRTYENTKKCLSLDEVFVATDDRRIFEHVESFGGKVIMTSSGCPTGSDRLIEAVQNTPIFKEAAIVVNIQGDEPCLEPSIIHEVVQLLLQDSNNVMSTAVTKIHSEAEALNPFVVKCCLDRQGNALYFSRSLIPSNPSAKFDPRTVYFKHIGIYGFRREFLFTYGKLGTTPLQLAEDLEQLKVLEHGYKIKAAIVGSASLSVDHPEDIKKIESLLLCKQNICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQD1</accession>
    <name>A0A0C1HQD1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgl</name>
        <name evidence="9" type="ORF">DB41_GG00110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384616.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76403">
        <property type="protein sequence ID" value="KIC76403"/>
        <property type="gene ID" value="DB41_GG00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.895"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="33"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="255" mass="28845" checksum="8D1289FA2DEC8D81" modified="2015-04-01" version="1">MLNSSWKTKIQVFDDRRDVVAAGNYREALLYSVEQFIELANACIENQGYFAVALSGGSTPKAIFQLLTSLENRGRIDWSKVLLFWSDERSVPPTHPESNYLNAMEAGFNALPLKADNIFRMQAENNIEENAWHYQDLIQTKIPKKNFDAVLLGMGEDGHTASLFPQTSGLHVRDRLVIGNFIPQKNTWRMTLTYDCINAASYILLYVFGKGKEDMVFQALKGPYNPELIPVQKVGTPTHKALWVLDDNSRSLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQF0</accession>
    <name>A0A0C1HQF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GE00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000090">
        <property type="protein sequence ID" value="KIC76418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384580.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000090.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76418">
        <property type="protein sequence ID" value="KIC76418"/>
        <property type="gene ID" value="DB41_GE00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002146753" evidence="2">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="9243" checksum="1579701052249DC5" modified="2015-04-01" version="1">MKKLNLILTALGVICFTCLSASAFCATPGKKIDDALDKGKVKYKKFKNIVKDKYSDAVEKSKDKLDEAKEKVKDKINSTKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQK2</accession>
    <name>A0A0C1HQK2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384546.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76463">
        <property type="protein sequence ID" value="KIC76463"/>
        <property type="gene ID" value="DB41_GC00300"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.860"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="144"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1142" mass="127146" checksum="18EBEED0AADAE43A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQY6</accession>
    <name>A0A0C1HQY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FM00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76568">
        <property type="protein sequence ID" value="KIC76568"/>
        <property type="gene ID" value="DB41_FM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="60" mass="6837" checksum="6A8E1FE864699069" modified="2015-04-01" version="1" fragment="single">QAWRDPIPYIDVGGLIRSKRDTVTLNSCPGAAFHDHSFQSPTYEKVFKYHFEKVKGLGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRL2</accession>
    <name>A0A0C1HRL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TPR repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_EM00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000052">
        <property type="protein sequence ID" value="KIC76768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76768">
        <property type="protein sequence ID" value="KIC76768"/>
        <property type="gene ID" value="DB41_EM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="344"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="428"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="470"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="512"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="596"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="680"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="737" mass="83737" checksum="8F6551F662352DE8" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRM7</accession>
    <name>A0A0C1HRM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YbiT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ybiT</name>
        <name evidence="5" type="ORF">DB41_EJ00080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76778">
        <property type="protein sequence ID" value="KIC76778"/>
        <property type="gene ID" value="DB41_EJ00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.523"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="22"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="337"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="369"/>
            <end position="376"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="551" mass="61703" checksum="1F15E0DBA50CA6B3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSN5</accession>
    <name>A0A0C1HSN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein TrpH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trpH</name>
        <name evidence="2" type="ORF">DB41_DH00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383428.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77063">
        <property type="protein sequence ID" value="KIC77063"/>
        <property type="gene ID" value="DB41_DH00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.246"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="284" mass="31899" checksum="ED75FE2E46ED8415" modified="2015-04-01" version="1">MKEFRADLHCHTTCSDGTSSPEDVIRMAAELGLSGLSITDHDTIDAYSQVLPLAQQLGMEIIPGVEFSSFQGEVSVHVLAYSFPIDSPIIKDFCKKHVERRLHRNREILKKLAAHGFPLEEEDVLAAIAGKVLNASRTIGRPHIALAMLKKGYIHSIPEAFNKYLGEGKSCYAPGEYFTLEDTINIIHQAKGLAIIAHPHLVDHPPTLKKLLEMNFDGIECYYAKFHQEAHKRWLKIAKHRKWLITGGSDYHGALKPHIPLGSSWVAKDHFDILKEHFDKVSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSQ0</accession>
    <name>A0A0C1HSQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DF00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383393.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77073">
        <property type="protein sequence ID" value="KIC77073"/>
        <property type="gene ID" value="DB41_DF00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="6933" checksum="CC2F1E667FE3D79A" modified="2015-04-01" version="1">MHPISSASIESLPNELLLPILEACAVPSLFSVCKRWHYLLASEVMPSLSMLDSEAHTLTCFCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSY5</accession>
    <name>A0A0C1HSY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CV00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77163">
        <property type="protein sequence ID" value="KIC77163"/>
        <property type="gene ID" value="DB41_CV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="133" mass="15141" checksum="580D9C05A4D6387F" modified="2015-04-01" version="1" fragment="single">MNPSSSITIEHLPNEILLSILKKCASPSLFSVCGRWHYLLANEVMPSLYKQISKVHVPNGDVNKQALILDKIYRLGGKLSETVKVNAIFKQTFALASFLSPLELEFKWITEEKRYFTLANYSSYLVNINCLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT70</accession>
    <name>A0A0C1HT70_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">hemE</name>
        <name evidence="13" type="ORF">DB41_CO00370</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77268">
        <property type="protein sequence ID" value="KIC77268"/>
        <property type="gene ID" value="DB41_CO00370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.71"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="12">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="346" mass="38930" checksum="35DAE148C5D3B0DF" modified="2015-04-01" version="1">MMRTVDPAIINSKFLLALQGHNQGRPPIWLMRQAGRYMPEYRALRQKYSFLEMCHHPELIVKVTNLPLQAFGMDAAILFSDILVVAEAFEIGLSFEEGKGPVIARPLQTEKDVADLSAGAVAEKLAYVAEGIKLLLKELKVPLIGFCGAPFTLASYMIEGGSSRDLLKTKKWMLNHPTSFHLLLDKILQATIQYIEMQVQAGVHAFQIFDSWANHLSWGQFQEFSYEYMKKLVKVLQKYSVPAILYCRGSSVFAPKLAEASPQGIGLDWNCNLAYMRKYVPFHIALQGNLDPDILYAPPAKIEQEARQLVDTMHGDRAFIFNLGHGVKPDTPYDSVRLLVETVQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKY3</accession>
    <name>A0A0C1JKY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71945">
        <property type="protein sequence ID" value="KIC71945"/>
        <property type="gene ID" value="DB41_AE00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5495" checksum="4EE4CB4A2D88AF8E" modified="2015-04-01" version="1">MPFLKPPVRTLQLEQCPGMQKPHKGFPHKTYRLLFQPHGDQLRNLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL20</accession>
    <name>A0A0C1JL20_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_AC00060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MreC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244088.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000203.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71985">
        <property type="protein sequence ID" value="KIC71985"/>
        <property type="gene ID" value="DB41_AC00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2105"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC71985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="37552" checksum="A3C0C241F6D28666" modified="2015-04-01" version="1">MRKTSKPLLILFVLLLLTMSLPLTTSEWMRGSALAILSPIWESLSHLKGQKKQELKNLGPIDLHKNSMPEIPEPSYDAVAARIIFRSLGTWNSSLWINVGEETNEVYESPLVAKNSPVLVGDSVVGVIDYMGKRQSRVRLITDSGLVPSVRVARGYEQGKAIAEYIPDLLAYIHAHGEVFDNGREKMLAENVLRHLRLKLLEKKHTWYLAKGEIRGQSRPIWRTDGHLLRGSGFNYDFEDEQGPARDLRSGEPIGSSQEKAMPLIKVNDLLVTTGMDGVFPAGLKVAIVTKVDLLREGDFAFELEAKPTIGNLDDLTWVYVIAPSEFNGKDQPNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL51</accession>
    <name>A0A0C1JL51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BO00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000235">
        <property type="protein sequence ID" value="KIC71311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71311">
        <property type="protein sequence ID" value="KIC71311"/>
        <property type="gene ID" value="DB41_BO00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="9837" checksum="4E6C76A9028DF56F" modified="2015-04-01" version="1">MEWKDRVLYLAFMKCVVYQRGVVPLCCTPPAVLVWMLGMLAEMTVEAARYYSTSPRRVMSSPISCTLVMSTTAVAFYGEEKSQSKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLN8</accession>
    <name>A0A0C1JLN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Acylphosphatase</fullName>
            <ecNumber evidence="3 4">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">acyP</name>
        <name evidence="7" type="ORF">DB41_KR00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 4"/>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386517.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72185">
        <property type="protein sequence ID" value="KIC72185"/>
        <property type="gene ID" value="DB41_KR00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="6">
        <location>
            <begin position="12"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="10992" checksum="864768867A5C7340" modified="2015-04-01" version="1">MNRLNPFHELLELHALVSGHVQGVGFRSTTLHYASQLGLTGTVRNLKDGRVEIIAQGPKEKLEKLLSLIQAHFGSSYIACLEVNYSQPSNSYPQFQIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLV9</accession>
    <name>A0A0C1JLV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2431 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KQ00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386498.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72260">
        <property type="protein sequence ID" value="KIC72260"/>
        <property type="gene ID" value="DB41_KQ00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="DUF2431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2431" evidence="1">
        <location>
            <begin position="401"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="869" mass="99313" checksum="DABF2E6323131F90" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM91</accession>
    <name>A0A0C1JM91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative flagellar motor switch protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sctQ</name>
        <name evidence="4" type="ORF">DB41_AS00100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71656">
        <property type="protein sequence ID" value="KIC71656"/>
        <property type="gene ID" value="DB41_AS00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013385">
        <property type="entry name" value="T3SS_SpaO/YscQ/SpaO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02551">
        <property type="entry name" value="SpaO_YscQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="3">
        <location>
            <begin position="397"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="466" mass="52976" checksum="62F1BB48C3ACEE53" modified="2015-04-01" version="1">MYFCIDNLGSFYFIIKRSITFYEGVRVTSPKASMPYDWLKHIPTALLQLDEIPLIGSSPPFPWEDLSKGLEEIFQIPDFKIEPTPFQWRTKDELGAGMGPVIPLSCSIPSLEGQLTWIMAAEDIYRLISLLLNEDCHEHDVLEDEFLQGFYYFAAYEVIHLINKLPFDQSLSPQILQESSMPIEDSLCMDIKIQLQGKTLIGRMIVSPTFRRSWKEKYAERSLELPLHASLAEQLTIPVHIEAGRTSIHPSEWKTVRKGDFILLDSCTVKPYDDKGGRITLTVNGIPFFIGKIKDGNIKILDHPLYYQEEETFMSKIPSEEQDDSSLDFESELEFDSEMESDMESDFDSEMEAEDESEEASNLASNEKLKDREIEEELTSSEEQSSAVIPTETSVKIDEIPLSIIIEVGRLQMSVKKMLELQPGNLLELDVHPENGVDLVVNGRRIAKGELIRLGEALGVRILDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMZ0</accession>
    <name>A0A0C1JMZ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AE00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386662.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71941">
        <property type="protein sequence ID" value="KIC71941"/>
        <property type="gene ID" value="DB41_AE00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="150" mass="16880" checksum="8201234041E744DB" modified="2015-04-01" version="1">MSALPKKKLCWNCEGRVAFSDENCPYCGVYLSSSSLLTQHDKSLTHIAPFPSYRQDSSATYDINKVDEESSEEEEDSEAATSSANYPTSFLLPFVLLLTGSVFLIFGIILFSFSQEGILTLQWNANYWFLYLGTAGLLIFLSWRAMRSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNZ2</accession>
    <name>A0A0C1JNZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative rRNA methyltransferase YlbH</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ylbH</name>
        <name evidence="3" type="ORF">DB41_KQ00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386489.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72251">
        <property type="protein sequence ID" value="KIC72251"/>
        <property type="gene ID" value="DB41_KQ00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2022"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="194" mass="21918" checksum="0408896D739A395B" modified="2015-04-01" version="1">MLYIIAGRYKNRKIQFPKHTLTRPTTNKLRGALFNICQTYIEDASFLDLFCGSGAMGLEAISRGAAQATFVDEAKASLQCVRENIQSLGVEKQARPLWGEARTVLKKLAKQGEQFDIIYIDPPYETKGLSEEVISMIDESNLLKVEGMLFIEESKALLIDKEKWLTLQLESARKMGRTQLLQFKKISCPQSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP16</accession>
    <name>A0A0C1JP16_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidoglycan-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">omp16</name>
        <name evidence="5" type="synonym">pal</name>
        <name evidence="10" type="ORF">DB41_KP00080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386459.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000195.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72276">
        <property type="protein sequence ID" value="KIC72276"/>
        <property type="gene ID" value="DB41_KP00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2001"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039001">
        <property type="entry name" value="Pal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002152248" description="Peptidoglycan-associated protein" evidence="8">
        <location>
            <begin position="24"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="9">
        <location>
            <begin position="125"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC72276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="242" mass="27246" checksum="7365F447711D474F" modified="2015-04-01" version="1">MKLAPYCLLLNIFLISLSFTSCRRTSDDVWEDTKTAGRHIGRGVKSLGGKHGDSRQVYSPDEFYTMGKQSNSANIYANEDFIPLQDQPHDAELAMAESVSQQPRENPGDPGSTIPNIQFFKDPSTIQGLSGIFQSIKFDYNSNLIKGQENMTILRKVVDYLQRNPNTYIFIEGHTDERGAEAYNLALGSRRANAVRNALIAEGASPDNIFTISYGKERPAVMESHEEAWAQNRRAEFKIYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP63</accession>
    <name>A0A0C1JP63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JV00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73010">
        <property type="protein sequence ID" value="KIC73010"/>
        <property type="gene ID" value="DB41_JV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="126" mass="14428" checksum="353AD06E6207C138" modified="2015-04-01" version="1" fragment="single">CNICTNLQPFNPALENKPTSFRWAPILADREKSTVWLINSSSHVDYTRSAQIDLTFFREKDTQTLKRTIILPPHGFRIIYAQEDQELCQFLENTIGWFTAVSPNPYTSTYYFTEDSSGVVGGDHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP68</accession>
    <name>A0A0C1JP68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome hibernation promoting factor</fullName>
            <shortName evidence="2">HPF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpf</name>
        <name evidence="5" type="ORF">DB41_JV00060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with 100S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73015">
        <property type="protein sequence ID" value="KIC73015"/>
        <property type="gene ID" value="DB41_JV00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00839">
        <property type="entry name" value="HPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034694">
        <property type="entry name" value="HPF_long/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032528">
        <property type="entry name" value="Ribosom_S30AE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038416">
        <property type="entry name" value="Ribosom_S30AE_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16321">
        <property type="entry name" value="Ribosom_S30AE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Ribosom_S30AE_C" evidence="4">
        <location>
            <begin position="185"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="116"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC73015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="243" mass="28294" checksum="2C31EFB8FF240DB0" modified="2015-04-01" version="1">MFSLPITRFFCIIGANRNLKFLSQLHKIEVSMSRKSKAAEFVDEDYSLTINGRNVQVTEAMEGYIKDKLSKIEKYDIPIIDITITMDIQRFEHHVNLLVKLNHILIKSSAVTDDMYASIDKAVDKIQTQLKKYKQKIKDHHAKPLEMVDMAVNVLRPLKEVEAAEINEEIEAENASQRDKEYRPHHIVKQEKKPLKYLTLDEALMKMELSGDVFLLFRNEVDRKLNVIYRRENGDYGLLMPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPM0</accession>
    <name>A0A0C1JPM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386384.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72481">
        <property type="protein sequence ID" value="KIC72481"/>
        <property type="gene ID" value="DB41_KK00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="8147" checksum="50A50BFCB62C90CB" modified="2015-04-01" version="1">MDWRYYVTPAFIARTTEGTVEIRRLDTDQWEDKSFNQDIFHLIEQDGYSVPEAEALTIHEKYKTLLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRQ7</accession>
    <name>A0A0C1JRQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_JQ00020</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386189.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73151">
        <property type="protein sequence ID" value="KIC73151"/>
        <property type="gene ID" value="DB41_JQ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1799"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="202"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC73151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="270" mass="30669" checksum="0FDE689D9D97CB36" modified="2015-04-01" version="1">MYQDQGKLKQAEEYLHKALNITYELFDENRPLIANYCNTLALIYQSQGKLEEAAEQSKKSLNLTHELFGDNHPSVARYYATLALIYQSQGKLEHAVEYSTKALAIDCKLFGDNHPEAARSYRDLGAIYLDQGKLGQAAKYSIRALTIYHKFYGKNNPRAAITCNNLGQIYQNYGNLAKAVEYSTRALAINLKLFGKNHPQVAVCCNNLGRIYQQQGNFDKAFEHMSKALKLSYRLYGENHHKVIKSCNDLMALFLEVYSKQSGQKNNFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVA9</accession>
    <name>A0A0C1JVA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74995">
        <property type="protein sequence ID" value="KIC74995"/>
        <property type="gene ID" value="DB41_HY00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4776" checksum="F3FB79BFA6C7E2BE" modified="2015-04-01" version="1">MKREAKLRDGQAREKMSTLKAIPSFGKRIPARQLWKNFEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVW9</accession>
    <name>A0A0C1JVW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lspA</name>
        <name evidence="8" type="ORF">DB41_IJ00070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74536">
        <property type="protein sequence ID" value="KIC74536"/>
        <property type="gene ID" value="DB41_IJ00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1586"/>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC74536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="175" mass="20015" checksum="A6E627269B365FFA" modified="2015-04-01" version="1">MMKCFTLCLSCQMLAFIGCSALMVDIVTKYLTHYYLPISNHLFLWYPYGGIGLFKNFLGVEFSINHAINHGAAWGMFAELKDFLLVLRLFMMGGLIGYFLFYNRNKSWRLPLLLIMVGAAGNIIDTFVYGHVIDMFHFVLWGYDFPVFNVADSCITLGVAWLLISSLFEKEKSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWB4</accession>
    <name>A0A0C1JWB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HN00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75385">
        <property type="protein sequence ID" value="KIC75385"/>
        <property type="gene ID" value="DB41_HN00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4657" checksum="67C688E49CE2EB12" modified="2015-04-01" version="1">MIFVFQKPAPEQLRVSKELKKQGCFISPGDVCVVGKSAKKMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWS1</accession>
    <name>A0A0C1JWS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74886">
        <property type="protein sequence ID" value="KIC74886"/>
        <property type="gene ID" value="DB41_IB00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="126" mass="15080" checksum="900D878A34B3EB6F" modified="2015-04-01" version="1">MSQGENALNYVELNIVKIISLKLNFMKLFPLDLFTHYRGRSMSRESEVEVESFYVGEDNYFLPLNAKNYSKIIKRRGFKSFHVNIFRINFYSPNKQLFNWIEIVLLATSYFLTFLLKILKKVYPFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXE2</accession>
    <name>A0A0C1JXE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HH00330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75740">
        <property type="protein sequence ID" value="KIC75740"/>
        <property type="gene ID" value="DB41_HH00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6509" checksum="8166F3192CEF378C" modified="2015-04-01" version="1">MVIAKLTEIPIKLQLKKIAYLIGYTYLMAYFQYFLACFISFIYFLEIIKNMRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXM7</accession>
    <name>A0A0C1JXM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AC00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71987">
        <property type="protein sequence ID" value="KIC71987"/>
        <property type="gene ID" value="DB41_AC00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="73" mass="8670" checksum="DFF4907A4CC1973D" modified="2015-04-01" version="1">MYTIEYKAKIDVLLRQNFTKKKIYNRNCKRATKKHFLHCLYTQIKKRSKFSSQYAGRSSSLLPPAKKALIKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYD1</accession>
    <name>A0A0C1JYD1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dus</name>
        <name evidence="13" type="ORF">DB41_KR00100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72187">
        <property type="protein sequence ID" value="KIC72187"/>
        <property type="gene ID" value="DB41_KR00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2040"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="12">
        <location>
            <begin position="26"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC72187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="347" mass="38757" checksum="F44EB97AE8BD7C9B" modified="2015-04-01" version="1">MKDRTSFLQMPFQLGAIQLPNNIFYAPLAGCSDYPFRQMSANYHPGLIYCEMVKMDALVRFDQGTFHILDYARRMHPIGGQICGSKPEIAGQAAKIIEDLGFDVVDLNCGCPVDKVTKDGSGSGMMKNPALIGEVLEKMVAAVKIPVTVKIRAGWDENLINAPLITQIAEQAGAKAICIHGRTRQQGYRGAANWDWIKACKEVAKSIKIIGNGDIFDALAAEKMFEHTGCDAILVSRGTLGQPWIVEDIIRKLQGEEPRSRTLEDCRQALLEHFNYTINYQQTRRAVVDMRRVGCWYLKKSAGTRAFREQISRAESIEQVQDLILNFPLGEMNENEINDHSEGEISC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYI3</accession>
    <name>A0A0C1JYI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_KQ00170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72252">
        <property type="protein sequence ID" value="KIC72252"/>
        <property type="gene ID" value="DB41_KQ00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009623">
        <property type="entry name" value="UPF0242_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040578">
        <property type="entry name" value="UPF0242_PAS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18095">
        <property type="entry name" value="PAS_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06785">
        <property type="entry name" value="UPF0242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="275"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="377" mass="42838" checksum="8CB4E4DF2B509055" modified="2015-04-01" version="1">MPVQKGWNLLAFGIFCSSIGLLGIFWMMCRLSHKAEHGTRDNQPSVLEASEFSPKQSNIVELDMTQAKALEDLQEQYNELHAQVLAAQKDLEAKTKELLEREQNNQHLQEKLSASAAEYEMSKQAYESALDQQKLLLDESQKTITEQRECIDKKLQQIAQLEIKVSDLTYEIKTLIQLAEIENQSMPIYSSLPLESASSIYPPLSDIFEEEISCLPEKKVRNSMQANIQLKRCIDIAQKITGASHYYNTSSRFKDLAVDNYTLDLRRLFDSLRAENASAIIFYSQKENKILFVNNQSRSLLGWSPDKFVQSFNEIVEPSKDIWRQGIASLAIKNDNHISLKMKSKAGAQVEVHALLGIIPTGIFRYHVLGILYSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ41</accession>
    <name>A0A0C1JZ41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase, IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KK00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386391.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72487">
        <property type="protein sequence ID" value="KIC72487"/>
        <property type="gene ID" value="DB41_KK00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1948"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="2">
        <location>
            <begin position="4"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="128"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="541" mass="61938" checksum="13D8EDC41D1608DE" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ55</accession>
    <name>A0A0C1JZ55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_Tnp_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KK00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72502">
        <property type="protein sequence ID" value="KIC72502"/>
        <property type="gene ID" value="DB41_KK00280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1966"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027805">
        <property type="entry name" value="Transposase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13613">
        <property type="entry name" value="HTH_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_4" evidence="1">
        <location>
            <begin position="45"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="14373" checksum="94A89E4CBCF2B16C" modified="2015-04-01" version="1">MLNHILTSFEIRRLTGVKRTTFDKMVQILQQADKAKKIKGGRKYKLSLEDMLLMALEYMREYRTYFHISQSYGVSESSAYKAVKWIEDTLIKHPEETGKIIAGYFTMRDFMSSTYQSNIIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ61</accession>
    <name>A0A0C1JZ61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HH00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385202.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75716">
        <property type="protein sequence ID" value="KIC75716"/>
        <property type="gene ID" value="DB41_HH00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="106" mass="12333" checksum="D0400574848B72CC" modified="2015-04-01" version="1">MPMPDLKDGVNLKIFIGCLITSELRMHLNQSLLWKQNKITPELNSALREIHFQDKDYIGIYPTTNKISLMDLKKIEKEILQLLTTYCPLLPTEKIKILIFSQVFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ75</accession>
    <name>A0A0C1JZ75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HH00340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243937.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75741">
        <property type="protein sequence ID" value="KIC75741"/>
        <property type="gene ID" value="DB41_HH00340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1233"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="700" mass="78892" checksum="260D027C2DDDAF4E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZB6</accession>
    <name>A0A0C1JZB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KI00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72557">
        <property type="protein sequence ID" value="KIC72557"/>
        <property type="gene ID" value="DB41_KI00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="104" mass="12221" checksum="DB47FA0004A02262" modified="2015-04-01" version="1" fragment="single">MHKLPLTGSPEILELKVKKDLAFLKMTPGTAQLYKLNRKTGRLIFDNLKDKHAHLIHWKSNHLHLLTTDGYLYRWKDNEPRAKQAVCFLGAFEQAYFEQNFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZI8</accession>
    <name>A0A0C1JZI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KH00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000188">
        <property type="protein sequence ID" value="KIC72617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244046.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000188.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72617">
        <property type="protein sequence ID" value="KIC72617"/>
        <property type="gene ID" value="DB41_KH00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="34"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="10342" checksum="0D009A0C7A785914" modified="2015-04-01" version="1">MAKKIFAATGYSGEERRVEAALHGIDLIAIKRSKLKGFHLQAKRWIVERTFAWFGKCRRLSKDYEALPNTSQAFLHLAMIRLIVRRRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZP6</accession>
    <name>A0A0C1JZP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GW00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384921.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75936">
        <property type="protein sequence ID" value="KIC75936"/>
        <property type="gene ID" value="DB41_GW00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="256" mass="28837" checksum="896B593E0472626D" modified="2015-04-01" version="1">MSSLKSEYLSLIAQVQSYLIQEFSSKAFLEVNRSSYADYRLFAASCLPQAIKKALPPQFPEASKVEASPVVAAPLSSTVITHEKHPKDTLEVLPADSKSNLTSEQPLPSSSSPNSTEFVPKAINLEFLAPALTSPDFSDFHKIFAERFPEQMILTDIPNDEAAKIVKQMWKNDNQRDCLLLVLESASSDPRHALFLANLRKAIQIVYRVPIEIIEKNCLDSSQKNFIIELAPLDIYFQEPHRKVELWNFISSQLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZP9</accession>
    <name>A0A0C1JZP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KD00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72722">
        <property type="protein sequence ID" value="KIC72722"/>
        <property type="gene ID" value="DB41_KD00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="8"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="5969" checksum="429D9414A16F4768" modified="2015-04-01" version="1">MGVKSACSTHLSHQLFIKLYGRGLEIINRLRKNMKNKLMSLADKILLKKRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K062</accession>
    <name>A0A0C1K062_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GN00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76091">
        <property type="protein sequence ID" value="KIC76091"/>
        <property type="gene ID" value="DB41_GN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4805" checksum="D3D2A6591B862410" modified="2015-04-01" version="1" fragment="single">TAKKRCFKPQGEDLQRLRLTPFDEAQIVAYLKKICGRTPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0G6</accession>
    <name>A0A0C1K0G6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76660">
        <property type="protein sequence ID" value="KIC76660"/>
        <property type="gene ID" value="DB41_FB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5122" checksum="416BB8887B251A78" modified="2015-04-01" version="1">MGNLYPSIQLKKIKKLLNFKDFSSFNLAITPFVEDLTFYHGRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0J1</accession>
    <name>A0A0C1K0J1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein lap1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">let-413_2</name>
        <name evidence="3" type="ORF">DB41_FB00270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243828.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76685">
        <property type="protein sequence ID" value="KIC76685"/>
        <property type="gene ID" value="DB41_FB00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.638"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="448" mass="50525" checksum="DE83908589388717" modified="2015-04-01" version="1">MNPSSSVTIEHLPNEILVPILKACASPSLFSVCGRWRHLLANEVMPSLYKRIGKVHVPQGDVNKQALVLDRIYKLEEELSKAAKVNAIFKQIFTLASSLSPLELELKDKLKEKRYFTLTNYSSYLVNINRLLLWKKLPGGKEYLEQEEIKCLPLQRKGELFKEWIEENCKNITALDLSRVGLTYLPPEIGQLSQLQKLRLNQNQLTALPAEIGQLSQLQTLDLGQNQLTDLPAEIGQLSQLQELNLNQNQLTTLPAEIGQLSQLQVLDVNINQLNFLPTEIGQLSQLQGLYLNQNQLIILPAEIGQLSQLKALDLRINQLTAISAEAGQLSQLAKLNLDSNQLASLPAEIGQLSRLKELYLNNNQLAFLPAEIGQLSQLQELYLSNNQLTVIPEEIGQLSQLQRLYLNNNHLTSLPDEIGELPALQNLRVKENPLEYIPDKIKQPFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K130</accession>
    <name>A0A0C1K130_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GA00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384443.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76486">
        <property type="protein sequence ID" value="KIC76486"/>
        <property type="gene ID" value="DB41_GA00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009293">
        <property type="entry name" value="UPF0478"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06103">
        <property type="entry name" value="DUF948"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="144" mass="16284" checksum="7740858B7A330071" modified="2015-04-01" version="1">MDNHVIYAVCAVSATLIFSIIAFFLVKTLKAVLESVQHVNSSLFRMENKIEPLVQETLRLLENSNKIAIATQDKLSDLNPILDSINHVSAAVNKVTQSFNDNEDENPCNFYHVEKKNDWNEIVGDLIKLSTIGVKTWQKIKKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1C3</accession>
    <name>A0A0C1K1C3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FQ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76541">
        <property type="protein sequence ID" value="KIC76541"/>
        <property type="gene ID" value="DB41_FQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="8210" checksum="6D45A878DF8B86FC" modified="2015-04-01" version="1" fragment="single">MIRKPYPSDLNNQEWQVLEPIICKKKAGKPPKHARREMLNAIFYVLRTGCQWTDLPHDLPPWKSVYSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1F8</accession>
    <name>A0A0C1K1F8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JM00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73257">
        <property type="protein sequence ID" value="KIC73257"/>
        <property type="gene ID" value="DB41_JM00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="513" mass="57765" checksum="A1BA06BD681D4E98" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1G2</accession>
    <name>A0A0C1K1G2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease, YjgP/YjgQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_FM00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384269.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76571">
        <property type="protein sequence ID" value="KIC76571"/>
        <property type="gene ID" value="DB41_FM00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.720"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="358" mass="42186" checksum="0A0814BB3ADDD2B8" modified="2015-04-01" version="1">MIKIWPRYFLKETIKSFFLFILTFYGLYVLIDYSSHASNFHYHHFYFQVYEIALYYVCEFAPRMEVFIPFGLLLATIRTLTNLNIHNELVALMASGIPLRTLIRPFIFLGMAMVLLIYINTQFWIPLALQKIKQIEQTHRIHKHKGLLQLAVKNLNLKDNSHIIFHDYNSNEKKLVDAYWIRDINDIYRIKYLYPYGQPPVGHFIDHFKRQPTGELVIIESFDLLSFPEMRFHKRDLFQGITNPEDESLSELWKKLPPSFSIQSQKESQRASVFYHKMIIPWLCLLAVIGIAPFCVRYSRTLSPFFIYTLGIFGLVAIYLLLNAALVLGKRQVVEPWLATLFPFFICASLASYKYLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1G6</accession>
    <name>A0A0C1K1G6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-secreting ATPase</fullName>
            <ecNumber evidence="3">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">epsE</name>
        <name evidence="6" type="ORF">DB41_JM00150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73262">
        <property type="protein sequence ID" value="KIC73262"/>
        <property type="gene ID" value="DB41_JM00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1792"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013369">
        <property type="entry name" value="T2SS_GspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02533">
        <property type="entry name" value="type_II_gspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T2SP_E" evidence="5">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC73262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="542" mass="60511" checksum="1B19DE15656B485B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2B0</accession>
    <name>A0A0C1K2B0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiamine diphosphokinase</fullName>
            <ecNumber evidence="1">2.7.6.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">thiN</name>
        <name evidence="7" type="ORF">DB41_CX00010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.2" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383291.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77135">
        <property type="protein sequence ID" value="KIC77135"/>
        <property type="gene ID" value="DB41_CX00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00983">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="SSF63862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="SSF63999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPK_B1_binding" evidence="6">
        <location>
            <begin position="141"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="211" mass="23625" checksum="384E6E1911FC55E7" modified="2015-04-01" version="1">MDYPLSPQVAIVANGEISSYSQTKHLLSSFSKIIAVDGGLKHCQKMGVTPCLLIGDLDSLEKEVLEQYADLPLLKYPEDKNESDLELAIHKLLMEKVESIALFGVLGKRSDHLLYTLYLLSRHPSQLMIESEKETIFCLQGHNRIKTFIGQTISLIPLSPVYGIQTQGLKWELQNADFDKKFMSLSNVCNSNAVEINIISGDLICFLHKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2C7</accession>
    <name>A0A0C1K2C7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CW00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77155">
        <property type="protein sequence ID" value="KIC77155"/>
        <property type="gene ID" value="DB41_CW00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="9741" checksum="1EEE20BAA2E73DDB" modified="2015-04-01" version="1">MSADCYAGRTTFLDSKKLAHCIPPFGRRIKTRHQKEPFFSNKAKNQSHSFSPTKIAVSLNPQNLWLLANAWKVSPLSVNLSEKKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2I1</accession>
    <name>A0A0C1K2I1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EB00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000041">
        <property type="protein sequence ID" value="KIC76876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383717.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76876">
        <property type="protein sequence ID" value="KIC76876"/>
        <property type="gene ID" value="DB41_EB00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="141" mass="16929" checksum="095F1DC57335CB96" modified="2015-04-01" version="1">MLFFNFNPFNCIDLRSWRLITEAPPSIKTIPEELIVHIFSFLSPKELVNAQQVCKHWKKIGDEETLWKRHYQQHFKDEPLNISFSLKTPRSFRNSYLFYSLYESIDRKVKLEIASLRASPSYNPIFSERLLWMNQSQSFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2L4</accession>
    <name>A0A0C1K2L4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383114.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77250">
        <property type="protein sequence ID" value="KIC77250"/>
        <property type="gene ID" value="DB41_CO00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="178" mass="20970" checksum="B1753D78B8CD4F44" modified="2015-04-01" version="1">MTEEKFLKQFQQALRDEKFDCSYIEATDQTFYSRLLLFLGVDDKEREKILEVTAIKQELMQGLDSSDNPFYRIQFQAVFPFTVHPQASTQVSSLICYLNRLIELPGFEMDEINLTLNYRYILLYGERDFNKNLYFSIVGLIMLTLELFSSTLERIARGETTFNQILEEIIKIAQQFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2P4</accession>
    <name>A0A0C1K2P4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkaline phosphatase synthesis sensor protein PhoR</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">phoR</name>
        <name evidence="4" type="ORF">DB41_CK00130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383062.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77285">
        <property type="protein sequence ID" value="KIC77285"/>
        <property type="gene ID" value="DB41_CK00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.27"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="371"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="596" mass="67678" checksum="4B52F3B679AD3047" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2R3</accession>
    <name>A0A0C1K2R3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative esterase YheT</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yheT</name>
        <name evidence="3" type="ORF">DB41_DN00170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383507.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76996">
        <property type="protein sequence ID" value="KIC76996"/>
        <property type="gene ID" value="DB41_DN00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="63"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="314" mass="35494" checksum="5635F3516F2E0687" modified="2015-04-01" version="1">MLNKLNFQPLFGLSSPHVQTTLPTFLVNGKAPPSYEILVSLEDGDQLSCYLSNPYPGKPPTKIVVMVHGLGGSHQSGYLLRLSRKIYQAGHCAVRVNLRSGGVSKAKRPYHGGTSQDILSVLKWLKIHFPTSSLVLVGFSLGGNIVLKLAGELGEEAVQYMDHLIAVCPPVDLHHAVQYIEKEAYWIYHKYYLARVLKQSQKWLKDLSIQSMYEFDDKVTAPLWGFKDAIDYYQHCSSIKFIHSIAISTHILFAEDDPFIDCYRIDYNHIPSNVNVYMTTYGGHMGFLGWAGKEHGCHWMDKTLMDWIFSSSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3B4</accession>
    <name>A0A0C1K3B4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383136.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77266">
        <property type="protein sequence ID" value="KIC77266"/>
        <property type="gene ID" value="DB41_CO00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="319" mass="36841" checksum="9C9EEFCD92C323AB" modified="2015-04-01" version="1">MNPIAAYQSLQDDLMHDKVLGQFNLSLPVRATLKICTTVHWVWWLHRKKKLCTQQTIVPAALGTLTDFALKFTPTFIENTIRGIAKLILLATRIDECFQRIRALSNAFTELKEAIKGNYSPLIEPQWAKNPDSMFFSLKARNQAKSRIKNLEAYWRRLYYCTLNVLAKTFNLSMQLWDTYHAFIYSHDDVPEMYVNGIAWFKKLRKNKTYLCAKLEQYQPVIQKIFDLVKADITAEDLIKSTKNIGVKVIDTVDKLDQTATLVGEAIVTASKKTANTVIEIKSKLLCQGLVKPSIHTPFILNKRPRLFWPDKMLLKRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5I2</accession>
    <name>A0A0C1K5I2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coproporphyrinogen-III oxidase, aerobic</fullName>
            <ecNumber evidence="5">1.3.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hemF</name>
        <name evidence="5" type="ORF">DB41_IJ00130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385929.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74542">
        <property type="protein sequence ID" value="KIC74542"/>
        <property type="gene ID" value="DB41_IJ00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1594"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="PTHR10755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="SSF102886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="268" mass="30814" checksum="2351769AD01A6A33" modified="2015-04-01" version="1">MHNEYSSNKHSSLIHFLKNLRDEIIIAFEKFENSNRFTRKPWQHPTGGGGEISILRGEVFEKAAVNWSGVYGPHFPMSESSGPFFATGVSLITHMVSPHAPTVHMNIRYIETQERSWFGGGFDLTPMGFSYAEDTAHFHQTTQEFLNSIDPTLYPNFSQNAREYFYIPHRHKERGVGGIFFDHYNSGDYEKDLHLWQMVGKQFLAAILPIYIKRVPLPYSAQEKEKQLEARAHYVEFNLMYDRGTKFGFQSGGNPEAILCSLPPLAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6Q9</accession>
    <name>A0A0C1K6Q9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">infC</name>
        <name evidence="9" type="ORF">DB41_IB00600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74927">
        <property type="protein sequence ID" value="KIC74927"/>
        <property type="gene ID" value="DB41_IB00600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1496"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="7">
        <location>
            <begin position="83"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="192" mass="21718" checksum="A840BADEF9333FCF" modified="2015-04-01" version="1">MEFRLKVNREIRAPRVRLITQTGEQIGVVPLHEALARAEENGLDLVEISAGSNPPVCKIINYGKFRYDQTKKEKESKKAQHQVKIKEIKVKPNIDIHDLETKIRHARDFIAKGNKVKLTCMFRGREMAHPEIGEKVLRKVCEDLEEIATVESPSKLFGRMLIVILAPGGKKKKEGAKGLSNESQPTREEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAW4</accession>
    <name>A0A0C1KAW4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <shortName evidence="3">DHNA-CoA synthase</shortName>
            <ecNumber evidence="3">4.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">menB</name>
        <name evidence="4" type="ORF">DB41_GL00130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384743.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76272">
        <property type="protein sequence ID" value="KIC76272"/>
        <property type="gene ID" value="DB41_GL00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.947"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01929">
        <property type="entry name" value="menB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="76"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="120"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="276" mass="30597" checksum="18528AE9DF929DE6" modified="2015-04-01" version="1">MSVTSFLWTSIKQYVDIKLERTEEGIAKITINRPEVRNAFRPETVIEMQDAFEVCRNESSIGVIILTGEGKEAFCAGGDQRVRGDEGYIGVDGVARLNVLDLQKQIRSLPKPVVAMVAGYAIGGGHVLHIVCDLTIASDNARFGQVGPRVGSFDGGLGCSYLARIVGQKKAREIWYLCRQYSAQQALEMGLVNCVVPYEELEQETIRWCREMLQHSPLALRCLKSALNADCDGQVGLLELAGNATMLYYMTEEAQEGKKAFLEKRPPDFSTFPRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAY1</accession>
    <name>A0A0C1KAY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_4</name>
        <name evidence="3" type="ORF">DB41_GK00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76287">
        <property type="protein sequence ID" value="KIC76287"/>
        <property type="gene ID" value="DB41_GK00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.908"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="392" mass="44155" checksum="29639257ADD3DFE8" modified="2015-04-01" version="1">MFSTTKGIQPLSPSSTTPISMTSLYNAILQVHFPNGNRDLITQARILNKIYKIKPNLPIEEKVPYIFQKLFTLAASLSPTEFEENTKESKDFILSNYSSYLLDINRLLLWQKLPGGTKYLNQAQIKILPLKEKGKLLAPWTKASSKNITKLNLNRSSLNFLPAEIGQLSKLQRLDLRGNQLTVIPTEIGQLSQLQELDLSGNELNAIPTTIGQLSQLQRLWLSKNHLIGLPKEIGQLSQLKWLHLNKNNLTSFPAAIGRLANLIKLKLSDNQLTVIPTEIGQLSQLQELWLNKNQLTAIPAEIGQLSLLIRLWLNKNQLIVLPEEIGQLSLLIRLSLRDNRLNSLPATIGQLSQLQWLDLTNNQLIVIPAAIEHLPKQTRLLLKGNFLPDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBA7</accession>
    <name>A0A0C1KBA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ppiB_2</name>
        <name evidence="7" type="ORF">DB41_GC00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76437">
        <property type="protein sequence ID" value="KIC76437"/>
        <property type="gene ID" value="DB41_GC00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.831"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="171" mass="18853" checksum="5840F03F978A6386" modified="2015-04-01" version="1">MNAKKNPIVLLTTSMGNIKLELYPEKAPLTVKNFLDYAESGHFSQTIFHRVIDGFMIQGGGFNQAFDQKPTNAAIKNEAHNGLKNIRGSIAMARTNEIHSASSQFFINLVDNDFLNFKSPAAHEYGYCVFGQVIEGLEVVDKIGKVKTGSKGPHRDVPLETVEILSATQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBE5</accession>
    <name>A0A0C1KBE5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_IS66 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GB00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76472">
        <property type="protein sequence ID" value="KIC76472"/>
        <property type="gene ID" value="DB41_GB00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="2"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="74" mass="8505" checksum="5D5A68498E9109B8" modified="2015-04-01" version="1">MYDFAVPFTNNQGEQDIRMVKLKQKISGCFRKPKGGRIFCRIRSYISTARKQGWNVWDALADAIRGSPRLLAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBR6</accession>
    <name>A0A0C1KBR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_FM00050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384274.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76572">
        <property type="protein sequence ID" value="KIC76572"/>
        <property type="gene ID" value="DB41_FM00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.721"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="382" mass="43327" checksum="1FBD3D0282B24516" modified="2015-04-01" version="1">MPIIWRYLLKQYIKVFFLCLLSFIFILLITRLDEIAHFAALGSEGWIILWFVLHQIPYLLPVAIPISCLISAIILMQRLSQSHEMTAFRACGLSLREVLAPLLIASFFIAALNFYIVSELATQSHLQTGLTKMELRTINPLLLLHNKHLMRLRGIFSDTLGQSRTGEYAGDSILAIPDKHNASIHLILAKNLQASSVTFQGSQMTLISPTHGNHLPRHEALLVENIREMKTSIKDFAQLLQKKVWTLNNDHLRLALLRARIQDLKKEKALREHSDDNRVGLDLASRNLNRSYAELIRRFSISLAAFTFTLMGASFGMSISRNHHNRGLFYVIGLAALYIVAFFFAKGAEHQLVLSTLFYLFPQLIIILAALNMLSRLSKGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBZ2</accession>
    <name>A0A0C1KBZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gatA</name>
        <name evidence="9" type="ORF">DB41_FI00270</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76617">
        <property type="protein sequence ID" value="KIC76617"/>
        <property type="gene ID" value="DB41_FI00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.700"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="485" mass="52936" checksum="F1FEF84B7A6A73F7" modified="2015-04-01" version="1">MIHTLTACEIKDKFLKGDLTALAVTEAFLKRIDQYDNQIGAFLTVFKERAIEKAKQLDKKKALGEKLGKLAAVPIAIKDNIHIKEEISTCASKFLVNYRAPFDATVVRLLEEEDAILLGKTNMDEFAMGSSNESSALQKTYNPWNLKCTPGGSSGGSAAAVAGRLCPLALGSDTGGSIRLPASFCGVVGFKPTYGRVSRYGLVAYASSLDQIGPFATNTRDAALVMEVIGKHCEKDSTSLPAGADDYLTKMNSDIKGKKIGVPWHFLDTLAAEPKEVFNNSLEVLKSLGAEIVEIDLSILKYSLPVYYILATAEASTNLARFDGVRYGHRSSRAQTLEEIYDFSKSEGFGEEVKQRILLGTFVLSSGYQQAYYKKAQKIRTLIIQSYQEAFKRCDLVASPVSPFAAFEIGSIKDPIQMYLEDIYTIGINLAGLPAISIPAGFSTEGKPMGLQLIGPQKDEVGVFQVSHAFEKATAYHMHMPELVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC68</accession>
    <name>A0A0C1KC68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2147 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384006.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76697">
        <property type="protein sequence ID" value="KIC76697"/>
        <property type="gene ID" value="DB41_EY00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019223">
        <property type="entry name" value="DUF2147"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09917">
        <property type="entry name" value="DUF2147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2147" evidence="1">
        <location>
            <begin position="26"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="169" mass="19160" checksum="6CFB00DF07274375" modified="2015-04-01" version="1">MKNFLLFTSLFLLILCQGFAGEEIIGFWKTINEKTGRAESTIAIYEYQGKCYGRIVATFDEQGAIADTIDHPHDRAPGVLGNPYYAGLDIIWNLQQKGNKYTNGKILDPEKGRVYGAELWRQDDNLVVRGKLLCFGRNQIWLPLNEDELRGLFPQPGLPTFIPNIPKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCI7</accession>
    <name>A0A0C1KCI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rpsE</name>
        <name evidence="11" type="ORF">DB41_EI00120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383820.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76797">
        <property type="protein sequence ID" value="KIC76797"/>
        <property type="gene ID" value="DB41_EI00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.495"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="10">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="17833" checksum="BCAA494CFF7C897B" modified="2015-04-01" version="1">MAKSNDNPKKERTNSEFNEKVLYINRCSKVVKGGRKFSFSALILVGDGKGRIGYGFAKANELTDAIRKGGESARKNMITFASEGTSVPHEVLVNWDGAAILLKPAPAGSGVIAGSKVRAVLELAGLKDVMAKSVGSNNPINQVRATFKALSQLKKREQIKQMRGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCW6</accession>
    <name>A0A0C1KCW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DT00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76907">
        <property type="protein sequence ID" value="KIC76907"/>
        <property type="gene ID" value="DB41_DT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5797" checksum="01F2E908BB2A4DB7" modified="2015-04-01" version="1" fragment="single">NKRSCDAFKTFGNANFLFLTNWVVKTSIFILQKMLTYFYLVHRKGMTVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD14</accession>
    <name>A0A0C1KD14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgC</name>
        <name evidence="7" type="ORF">DB41_DQ00060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243787.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76942">
        <property type="protein sequence ID" value="KIC76942"/>
        <property type="gene ID" value="DB41_DQ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.368"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="31"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="448" mass="50538" checksum="3B770C0464A9C6A7" modified="2015-04-01" version="1">MATLQANHLGQHPKTHHTPAELSCDMSRVATIILGGGQGSRLYPLTRSDCKPAVTFGGKYRLIDVPMSNSIHSGCHKIFIVTQFLSKTLHDHIFKTYRPGTFTAGFVEVLSVEEKPHTKAWFQGTADAIRQNLEYLTDVPIDYFLILSGDQLYQMDYKKMMQVAQRTNADVVIATLPIEESQASRFGILKIDHNERITEFVEKPTDKEQIKTFKVSESTLKKFHLKNNKDGACLGSMGIYLFKRKALLKLLLTDMREDFGKHLIPNIIKNGNAAAYLYDGYWEDIGTIESYYHANLALTEDKPEFNWYDEKHLLVTNSLNLPAAKIYNTKVQQSIICEGSVIEAKEVFHSILGPRTQVGTGTVIKDCYILGNDHYRSPMQDNQTSKNYQIGQNCLIERAIIDKHACIGNNVCLNNADKLTHYNSNEIFIRDGIIIVPRGACIPDGFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDZ5</accession>
    <name>A0A0C1KDZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CS00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383211.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77197">
        <property type="protein sequence ID" value="KIC77197"/>
        <property type="gene ID" value="DB41_CS00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.104"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="333" mass="36475" checksum="2103FB0D64C480B0" modified="2015-04-01" version="1">MTYPSKDLPTAYLSAVATINQSQNEGNRAIESTSDKIGQFFRQQQQQIEADAAQQHHCQEQEKEAFARQKALHDLALQNQHQQFQVQLEERRSRDRQEDEAHYERLATNKAKFEAELKNRQEEFEKMQEVLSSTSPASTSGPYSVSDQPDYNAYPNLFRSFMTTVPSARLPLHLNPIITSGDQPQFAQASQTFPSAPAETWGTKPFPPLAHRDQYQATQPIQTHASASVGTSGLAPLPSLAPLGQSQSTQPSQTHTFASAGASELVALPSLPPPGQRQATQPTHPHASASVGTLELPSLPGLPSLGQPRLKQSNQAHTQASSSDWGLPPFSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE29</accession>
    <name>A0A0C1KE29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CO00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77232">
        <property type="protein sequence ID" value="KIC77232"/>
        <property type="gene ID" value="DB41_CO00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.34"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="13921" checksum="DB058870907BB7FF" modified="2015-04-01" version="1" fragment="single">SLPAEIGQLSQLQWLYLDQNHLTALPIEIGRLSQLEWLQLNQNQLTSLPAEIGQLSQLTRFFLNQNQLTALPAEIGQLSQLRWLYLNNNRLSSLPVEIAYLSEWLDLNLDGNPLESSPDEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H046</accession>
    <name>A0A0C1H046_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CH00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000253">
        <property type="protein sequence ID" value="KIC71134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71134">
        <property type="protein sequence ID" value="KIC71134"/>
        <property type="gene ID" value="DB41_CH00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4466" checksum="98A7AD6163E3B939" modified="2015-04-01" version="1">MEHKACVEGEEEPHTPIKGEDITEAASLLMISSSLLQFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1V2</accession>
    <name>A0A0C1H1V2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71669">
        <property type="protein sequence ID" value="KIC71669"/>
        <property type="gene ID" value="DB41_AS00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039365">
        <property type="entry name" value="IS701-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33627">
        <property type="entry name" value="PTHR33627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_5" evidence="1">
        <location>
            <begin position="20"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="155" mass="17534" checksum="599FB4CDA0A9BAA9" modified="2015-04-01" version="1" fragment="single">MDLEQLNSIREQLNEWINVFKANLGRSERVHWCRLYISGLILDGERKSIEPMAKRLPGGNEQAIQQFVNQSPWDHAAMQQQLAQHMAQSMGVKKGVLVLDDTSLPKKGKFSVGVARQYCGALGKIANCQSIVTWHYCEKGKEHFPILGELFLPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2S4</accession>
    <name>A0A0C1H2S4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386650.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71934">
        <property type="protein sequence ID" value="KIC71934"/>
        <property type="gene ID" value="DB41_AE00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="286" mass="33682" checksum="AF59E26303069975" modified="2015-04-01" version="1">MANNIMRICSLGDHFWYPEINKQINLLIKHPRHHIEVDCRTLYKKHSKTLSARMTVIASKIFHSLKLFFLSQYRLAFDRAVKTLIYSEEIKTKVVSKPSIASEPEPLKPLSEDDSFKPLTDVLTAEKIAKREQLALFNKKNQAAIAIQRFYRKMKFIDKKIEEEKASRIHVLNAFYALIQYSVHKENLKRLDENLNSQWRIVRFFKSENDLDQHIRLTALEQMKTLREKLVENTRISSTLKIKIDDENLAPEIVLKEINREISIQETNLAKIDKRIIELRSQKIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6A6</accession>
    <name>A0A0C1H6A6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JW00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000179">
        <property type="protein sequence ID" value="KIC73004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73004">
        <property type="protein sequence ID" value="KIC73004"/>
        <property type="gene ID" value="DB41_JW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="368" mass="41992" checksum="F9FFC27868116247" modified="2015-04-01" version="1" fragment="single">MHPISSASIESLPNELLLPILEACVVPSLFSVCKRWHNLLATEVMPPLYKQIAQLHFPGGNSTIQQTLMLAKFYQLNPGLTSTEKVYQVFKQVFTLAKSISTLEFKEKTEEKRGLTLVNYSSYLLNINRLLLWKKLRGGEEYLSREEIKHLPLEKKGALLRDWIAENRKNITALDLSRIDLTYLPPEICQLSQLQTLDLRENQLTALPTEIGQLSELQYLYLNQNQLTSLPAEISQLSQLQELHLSQNQLTALPAEIGQLSELQTLDLRENELNNLPAEIGRLPQLQWLGLSQNQLTSLPEEIGRLSQLQELYLNQNQLTSLPAEIGQLSQLEWLDLNQNQLTSLPEEIGQLSQLEWLDLNQNQLTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6S8</accession>
    <name>A0A0C1H6S8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetoacetate metabolism regulatory protein AtoC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atoC</name>
        <name evidence="8" type="ORF">DB41_JQ00100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386197.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73159">
        <property type="protein sequence ID" value="KIC73159"/>
        <property type="gene ID" value="DB41_JQ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1808"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="144"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC73159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="458" mass="51668" checksum="861B1F5199141A66" modified="2015-04-01" version="1">MPIEKVLIVDDEALIRDFLAETLKRKSLDVTTAEDGLKALALIKEHLFDIVITDMKMPDLTGIDLLQKIKEISPQTIIIVITAYGSIENAVEAMRLGAYNYLIKPFSPDTLEAVLEKAREHLTLIHENHYLRQQGPGSASQSLVIGDSVAIKKIMEDVIQIAKSNASVFINGESGTGKEVIAQAIHFHSQRSHKSFIKVNCAAIPETLVEAEFFGHEKGAFTGANAKRLGRFELANSGTLLLDEVTEIPIILQAKLLRAIQEQEFERIGGTKAVKVDVRIISTSNRDIKEAIFHKHLREDLYYRLNVIPIHLPPLRERREDIIPLARHFLEKFCNENHKENKQLSLEAEKKLLAYPWPGNVRELANIIERAVVMDSTSKVSPDHLFIDPQTSFKSEKLPAENGEFPTGLSLQELEKRLIIETFHQQDNNQTKTAKILGISTRKLRNKLQEYSLLKSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H732</accession>
    <name>A0A0C1H732_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JL00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000168">
        <property type="protein sequence ID" value="KIC73289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73289">
        <property type="protein sequence ID" value="KIC73289"/>
        <property type="gene ID" value="DB41_JL00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1778"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="129"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="255" mass="29656" checksum="0DFB3CB283FBE5C6" modified="2015-04-01" version="1">MNIFFQSINPSWLPYASLNWFIPNAEWYTQDLELLDLIDLVLCRTQETQRIFENLKLKCFFLGFTSHDCYLSHIKKDFSLFFHLAGGSEQKGTQPIVDSWLRNSSFPLLIILKHFCTVRPRQANLHWITHRVEEPTLRDLQNSCGIHLCLSETEGFGHYIMEALSTRAVVVTVDAPPMNEFIKDPRCLVPFKACSPQLLGTNYYVDPVQLEVVINNLKELPIKELRRIGLENRAMYLKKTYQFTNSLKKLIDSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAG4</accession>
    <name>A0A0C1HAG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative type III secretion protein SctL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sctL</name>
        <name evidence="4" type="ORF">DB41_AF00090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386687.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000206.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71823">
        <property type="protein sequence ID" value="KIC71823"/>
        <property type="gene ID" value="DB41_AF00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="3">
        <location>
            <begin position="78"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="42"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="218" mass="24746" checksum="572458C9592A6831" modified="2015-04-01" version="1">MKKKFFSLIHGNGVHVAPETRVIPAEEFSQALEAYQLMEEVKKDALKYKQGVAEEIEKLKEQAQKEGFEEGFKKWVEQIAKVEEEIINVRHETEKVALPIALKAAKKIVGRELELSETAVVDIVSNSLKAVVTHKKITIYVNKKDLEALEKNRQQVKDLFESLETLIIRERADIESGGCIIETEGGIINAQLENQWRIIENAFDRMMKQHGKAAQGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB02</accession>
    <name>A0A0C1HB02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tyrosine-specific transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tyrP_3</name>
        <name evidence="9" type="ORF">DB41_AD00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000204">
        <property type="protein sequence ID" value="KIC71963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71963">
        <property type="protein sequence ID" value="KIC71963"/>
        <property type="gene ID" value="DB41_AD00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="399" mass="43697" checksum="B9489FA010CBA2BD" modified="2015-04-01" version="1">MPTINNKFSTLSGILLVSGTCIGAGMLALPVVTGFSGFLPAMAVNLICWIFMLITGLLFLEATLWMKEEANVLSMAARFFGPCGKWIAGAAFLFLYYSLEVSYIAGGTPLFISQVESLGFHLTGYKGYIAFASLFGFIVFLGSQVIDRVNLILMIALVFSYFLLIGLGSTEVQMSFLTRRNWNAFLLAMPTLFSAYGYHNIIPSLTTLMHRNVQQLRTAIVIGTSLPFIIYTLWQWMIIGTIPESQIAKAVAEGIPVTQLLHTITGHPWIGFLATYFGYFALITSFLGVSLSMVDFLADGISAKSQGWTRILLCLIVFIPPAIFAGSYPGIFLEALGIAGGFGEAILNGLLPIGMVWLGRYRFYLPPQEQVRGGKPLLLALLAFTLLIIALETYHLVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBG1</accession>
    <name>A0A0C1HBG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72113">
        <property type="protein sequence ID" value="KIC72113"/>
        <property type="gene ID" value="DB41_KU00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5105" checksum="AFD704D25EBCE6A3" modified="2015-04-01" version="1">MTKLFDHFNVQSSFLSSHKLVLKAYKARLYEEVLTYPHCFAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC11</accession>
    <name>A0A0C1HC11_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prs</name>
        <name evidence="4" type="ORF">DB41_IB00870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385777.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74954">
        <property type="protein sequence ID" value="KIC74954"/>
        <property type="gene ID" value="DB41_IB00870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1522"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="3">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="308" mass="33574" checksum="F2072AF6E370BD44" modified="2015-04-01" version="1">MIPTAPNFVVFAGTSHPELSKEVAKDLKVKLGKISIQRFPDQEIFLEVLEDVSNKDVYVIQSLAFAPNEYLMELLIMVDALKRASARRITAVIPYYGYCRQDRQDKPQVPITAKLVADLLQKAGVACIIAADLHAGQVQGFFDIPVINLQCMPLLAKVFRKFETDKLVVVTPDVGSIKLGRDYANHLNVGFAVVNKQRLKAGEVEALQVIGDVKGKDVLLADDMCSTGETLTSAAKACREKGAKRIWASMTHGLFVGEALPLINQSCIEALITTNTVPFKGLAEKTTKNVHVASAAPLFARAILNLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC23</accession>
    <name>A0A0C1HC23_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmH</name>
        <name evidence="7" type="ORF">DB41_IB00970</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042242994.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74964">
        <property type="protein sequence ID" value="KIC74964"/>
        <property type="gene ID" value="DB41_IB00970"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1531"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5528" checksum="D9CF088C8CF151B6" modified="2015-04-01" version="1">MKRTYQPSKRRRKSEHGFRKRMKTADGRKIINSRRRRGRKALTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE46</accession>
    <name>A0A0C1HE46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sporulation protein RMD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rmd1</name>
        <name evidence="2" type="ORF">DB41_JV00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386241.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000178.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73018">
        <property type="protein sequence ID" value="KIC73018"/>
        <property type="gene ID" value="DB41_JV00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1833"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="1">
        <location>
            <begin position="48"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="30754" checksum="A55B933706E3BFFC" modified="2015-04-01" version="1">MDCRAYCTAASYKIKLFYEILRQRFPAASYRDAVHCSIPLPNLPPGDVFFFSYGAMVCWGLPKEIEREMLKLVQPYEEKHSDEIETDEFTYLYGEAPRILEDEIILPNQEMLTKLAISHGLAQSVKLGTFENAIQTTFNQSKHIPEELASKGKISYSKKAIRKKMGELFLARNSINLHADVLDTPEFFWEYPELEPLYTMVANYLDIESRVEVLNQRLDVVHELFQMLGSELNHQHSSRLEWTIIWLIIIEVMLNLLKDVFRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE70</accession>
    <name>A0A0C1HE70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HH00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243935.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75719">
        <property type="protein sequence ID" value="KIC75719"/>
        <property type="gene ID" value="DB41_HH00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="728" mass="85919" checksum="40E89D3E8084CE21" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEH1</accession>
    <name>A0A0C1HEH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HB00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000112">
        <property type="protein sequence ID" value="KIC75834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75834">
        <property type="protein sequence ID" value="KIC75834"/>
        <property type="gene ID" value="DB41_HB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7520" checksum="0DD470ED6EA7E40E" modified="2015-04-01" version="1">MMLRENHISEEHKVGNIEACMRGRSTHSSEEAFVMKGGAKGLNCSIQLNKSSRSTRNLWGWGKGWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEJ3</accession>
    <name>A0A0C1HEJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="6">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dusC</name>
        <name evidence="9" type="ORF">DB41_GZ00230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384966.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75859">
        <property type="protein sequence ID" value="KIC75859"/>
        <property type="gene ID" value="DB41_GZ00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1088"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0288">FMN</keyword>
    <keyword evidence="5 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="8">
        <location>
            <begin position="16"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="324" mass="35939" checksum="1DA87E399F046D46" modified="2015-04-01" version="1">MHLLSKDAFGCPYLFLAPMEGVGDRCFRKAMATIGGFDEGVTEFIRVPSNAHVSSLAKVYDSHEISPIPLAAQLMGSEPNLMAEMALEIARRGAPRIDLNCGCPSNKVTGRGAGSSLLKEPGHLYEVARALVKAVKVPVTVKMRSGYEDTSLFKENLLAAQESGACFITLHPRTKVEGYGPPARWDLIAEAKSILKIPVVGNGDILCVEDAVRMLRTTQCDALMVGRGSVINPFIFHHIRAYFSGKAFIPPWDSLDTYLKTYLSEIPLTTPVRNKINKMKQLLSFLYKANPQLLSYRQQMLTSQFNHLDAFMEDAMHHLKSFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HER3</accession>
    <name>A0A0C1HER3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ISRin1, transposase orfA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GW00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75929">
        <property type="protein sequence ID" value="KIC75929"/>
        <property type="gene ID" value="DB41_GW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027805">
        <property type="entry name" value="Transposase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13613">
        <property type="entry name" value="HTH_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_4" evidence="1">
        <location>
            <begin position="50"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="10773" checksum="DC3A6E3049975ECF" modified="2015-04-01" version="1" fragment="single">MGKYEELKVLSAEQFKRVTGVKRETFERMVEILVEAQNRRYRRAGRKGGLTIQNKLLMALEYLRGYRTYFHLGRSYRLSESGCYRACRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG21</accession>
    <name>A0A0C1HG21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_3</name>
        <name evidence="3" type="ORF">DB41_GI00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000094">
        <property type="protein sequence ID" value="KIC76334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76334">
        <property type="protein sequence ID" value="KIC76334"/>
        <property type="gene ID" value="DB41_GI00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.902"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="411" mass="46070" checksum="D5218E14C716B46C" modified="2015-04-01" version="1">MASLYKAILQVYFPDENGDLEKQASILDKIYKIESNLSIEEKVPYIFQKLFAIAASLSPLEFERNTKESKVWTLSNYSSYLLNINRLLLWQRIPGGTAYLNQPQIKALPLKKKGELLTLWIEEYGKTITYLSLDSSGLTFLPPEIGQIIKLEMLYLSNNQLTAIPAEIGQLSQLEILQLSNNQLTAIPAEIGQLSQLEGLHLSNNRLNTIPAEIGQLSQLQMLDLSNNQLTVIPAEIGQFFKLVGLDLINNRLNTIPAEIGQLSQLEALDLSNNRLNTIPAEIGQLSQLEALNLSNNRLNTIPAEIGQLSQLQMLDLSNNRLTTIPAEIGQLSQLIRLWLNKNQLITIPKEIGKLSLLVRLSLRDNYLNTLPATIGELTRLHCLDVANNPIERLPKPTRLLLKGSFLPDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH67</accession>
    <name>A0A0C1HH67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FH00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76634">
        <property type="protein sequence ID" value="KIC76634"/>
        <property type="gene ID" value="DB41_FH00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.669"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="330"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="433"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="506" mass="59259" checksum="36EF388DF9084763" modified="2015-04-01" version="1">MENLLQVDAKVKYALDFMESSLAQSGAPHFKAFWEVRNICLQLFKENLSPLVRTQLWTKYSELSKEARRLKEMLDEQSSFAAEQIEIAIVALENDIKLFEEQVTKIANPDLGPIPTRLSVKALFYQDTQKRLNLLNVQASRVNALRKELIKTDMRVRQKNKFFQRLSEIGDQVFPLRKELIKEVSQTFSDDVEAFIEDSFKGNFDDSLFALREEIKDLQGIAKVLTLNTHAFTHTRMRLSECWDKIKLAEKERKKERAQLKATFKQNFYLVQAKIHELKKQYESSELSDDQAYKHLDEISKFMRNVELGRDEIKALRSEMFAVKDQILEKQKAQEQVRLQHEQEKEKQRKAKIEEVKNEIEQLGNNARSLEAQELATARDELAQKIQNSSFNKFEKQEVERLYKSLRSLITDVLSDKEEQALLSLSEDDRQSIEQLREVLKQRKERRQAIKAQLESLRKAGGVSGLDFEKAMNNNELIKSEKERLEKINQGIQEIENKIVQFQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHA8</accession>
    <name>A0A0C1HHA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FB00260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76684">
        <property type="protein sequence ID" value="KIC76684"/>
        <property type="gene ID" value="DB41_FB00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6586" checksum="0F8223F5CBF1D1B2" modified="2015-04-01" version="1">MLKRFQECREPSDSSKATNIFSAICFQTLLVRFGLFMYILPRKRLKICMALKEAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI92</accession>
    <name>A0A0C1HI92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IQ00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74303">
        <property type="protein sequence ID" value="KIC74303"/>
        <property type="gene ID" value="DB41_IQ00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5421" checksum="2C7D2D69276ECA17" modified="2015-04-01" version="1">MLILSKIQLLYCKNSYPKFNKKLRMAFFLDNFSIAILLILFVNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIH9</accession>
    <name>A0A0C1HIH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_DH00170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383431.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77069">
        <property type="protein sequence ID" value="KIC77069"/>
        <property type="gene ID" value="DB41_DH00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.252"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="105"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="194"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="345" mass="39960" checksum="922220E276C97D0A" modified="2015-04-01" version="1">MSFTPKFNITNNITAALVKIERTRGFLEAARLSDEWIAKMQAKTLILEAHYTTHIEGTHLTLDQSEQLLTGHKIENADPEDVRELLNYRKAFDLVADYLGSGEPIREGLIREIHKKLVEGVRGNSATPGEYRKIQNYVANSKTKEIIYTPPPAFQVPLMMSELVKWLKIEQEINPVLVAGIAQFQLVHIHPFLDGNGRSARLLSTLYLYKTGYDFKRLFTISEYYDRDRSNYYKAIQSVRENNMDMTMWLEYFVNGLATQLQEVQNRGQEVMKLDILSIQHNLSKREKEAIERALDQKGLSIKEFQLLFPETSKRTLQRELKHLLELGLLKVEGATNDRRYRVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ33</accession>
    <name>A0A0C1HJ33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">nrdR</name>
        <name evidence="11" type="ORF">DB41_IJ00090</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385926.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74538">
        <property type="protein sequence ID" value="KIC74538"/>
        <property type="gene ID" value="DB41_IJ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1588"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="10">
        <location>
            <begin position="48"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC74538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="171" mass="19782" checksum="9FE301D4A5D48AF5" modified="2015-04-01" version="1">MKCPFCHHRELKVIDSRDAAELNAIRRRRECLGCLRRFTTFETVELTVQVHKRDGHYEDFQQQKLVNGLEAACRHTTISHDHVIALAAEISEELLQRQVHVVSTKELGEIAMKHLQALDEIAYIRFACVYKRFKDIEELMQAIKTIQPKESLNKSSQACPTEKPLAESLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ39</accession>
    <name>A0A0C1HJ39_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ras-GEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_CK00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383060.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77284">
        <property type="protein sequence ID" value="KIC77284"/>
        <property type="gene ID" value="DB41_CK00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="PTHR23113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="SSF48366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="257"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="627"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="672" mass="75925" checksum="F7C4DEE20E5A5ECC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJF5</accession>
    <name>A0A0C1HJF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_II00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385908.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000142.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74628">
        <property type="protein sequence ID" value="KIC74628"/>
        <property type="gene ID" value="DB41_II00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="229" mass="25665" checksum="AB940F204D45C013" modified="2015-04-01" version="1">MSIFSTQPIFQTLPMAQPMVQTLSNTPLVFQTFPKTELIFQSLPNAELISRLLPKAEPISQSLWKAELISQPLLEAGPISQLFSEIKPMPLTSEMECPFAWKSESYSLNKLIQLFPSGAKLTISFTTTRSSKVLGYLPLIGTAMGIFRIYKGIQEYRFFNSIHLHSLTTRSFKWMARGVFESIPVLGGLICLIMDIISTILSKESSGILSNFEEETPCGYCHQCGYCNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN30</accession>
    <name>A0A0C1HN30_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="9">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">hppA</name>
        <name evidence="10" type="ORF">DB41_HG00030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385147.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75748">
        <property type="protein sequence ID" value="KIC75748"/>
        <property type="gene ID" value="DB41_HG00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1171"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="604"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="676"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="9">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="695" mass="72989" checksum="05261BC850CAF387" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HP38</accession>
    <name>A0A0C1HP38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug resistance protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">emrB</name>
        <name evidence="7" type="ORF">DB41_GP00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384825.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000101.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76033">
        <property type="protein sequence ID" value="KIC76033"/>
        <property type="gene ID" value="DB41_GP00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.992"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="516" mass="57720" checksum="DB324C8A2EAFDBFD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPD5</accession>
    <name>A0A0C1HPD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GN00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76098">
        <property type="protein sequence ID" value="KIC76098"/>
        <property type="gene ID" value="DB41_GN00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7343" checksum="A58586CDE49113C2" modified="2015-04-01" version="1">MQRLYLNKNRLTSLLAEIRQLSRLEALYLKDTQLTTLPAEIVQLSNWLDLKLEGNSLQSISRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRA1</accession>
    <name>A0A0C1HRA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane protein OprM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">oprM</name>
        <name evidence="5" type="ORF">DB41_FD00070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76648">
        <property type="protein sequence ID" value="KIC76648"/>
        <property type="gene ID" value="DB41_FD00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="481" mass="53088" checksum="A1545507A5491AF9" modified="2015-04-01" version="1">MYNLKTKVYEGGRFFLACIGLFMVSSCVFRPNYTRPPVNVPENWRLPVHEACGLANIYWWQQLGDPVLEALIIEALKNNYTLQAAMASVEAYYSQFRATNSQLFPQITGDGSALRQGLSAQSNLGLAQNLRLINSFSALLSCAYELDIWGRLGSASDVALAQYLGEIQARRTVILTLVSALANSYITLRQYDEQLQVAQQTLNSFQESLELMTDQWEQGESSELPITQASAERDTAASLVKQLEVNVAQQENLLCILLGRNPGNIRRGKILEELAQPPSIPAGLPSDVLEQRPDVMQAELNLIAAHANVGVAKANLFPRISLTGYYGNQSFALNTLFKGAACAWQVGTTFSEQIFNGGLYIAQLDQAHAQEKQALFSYYNTIQTAFKEVENALISHSKSLEVLEIQKDQVQALQKSLALASLAYDNGQVDYLNVLDAQRNLFSAQLNLVQARSVTYTTFIEVYKALGGGWVQEADTVATEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRG0</accession>
    <name>A0A0C1HRG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76713">
        <property type="protein sequence ID" value="KIC76713"/>
        <property type="gene ID" value="DB41_EY00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="6004" checksum="5D3951EA36CA11C1" modified="2015-04-01" version="1">MSAFFLGPLKEETLKVGAITSYILTFSLKNMEKPVDLNSYFKLNNLFVMRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRK0</accession>
    <name>A0A0C1HRK0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 15" type="primary">rpe</name>
        <name evidence="15" type="ORF">DB41_EO00110</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76758">
        <property type="protein sequence ID" value="KIC76758"/>
        <property type="gene ID" value="DB41_EO00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.543"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="195"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="14">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC76758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="236" mass="25918" checksum="3706BCF5983FDDF2" modified="2015-04-01" version="1">MIKTNSIKVATSILAGDFGYLADTAKKIEDSGADSLHIDIMDGNFVPNLTMGPQAVAAINRATNMFLDVHLMVYHPFDYIERFVEAGADNITIHFEATEDVDETLEYIRKCNIKAGLAFCPETSASMIPKYLNKCDLILLMTVHPGFGGQTFMPEVLEKISFTRECLTKLDICQGGMTAKEDFPEKLPPFDIQVDGGITPETARLCVKAGANILVAGTFLFKSPNMHEGVESLRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRX8</accession>
    <name>A0A0C1HRX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">aspS</name>
        <name evidence="9" type="ORF">DB41_EC00210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383741.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76873">
        <property type="protein sequence ID" value="KIC76873"/>
        <property type="gene ID" value="DB41_EC00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.448"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="155"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="203"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="225"/>
            <end position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="538"/>
            <end position="541"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="595" mass="67885" checksum="5B97B95E80C32CD2" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS27</accession>
    <name>A0A0C1HS27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DW00150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383694.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76903">
        <property type="protein sequence ID" value="KIC76903"/>
        <property type="gene ID" value="DB41_DW00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="11098" checksum="95A131E58ED7E9DF" modified="2015-04-01" version="1">MAIRYSNLGAIYQEQGTLNKAVEYSHKALAINLTLFGENNSKIATNYNNLGEIYQLQGNMEKALECVNHALRIAINIYGNNHSTVDALVTRQQTLKKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSC7</accession>
    <name>A0A0C1HSC7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ogt</name>
        <name evidence="10" type="ORF">DB41_DN00090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383499.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76988">
        <property type="protein sequence ID" value="KIC76988"/>
        <property type="gene ID" value="DB41_DN00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.299"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008332">
        <property type="entry name" value="MethylG_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02870">
        <property type="entry name" value="Methyltransf_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_1N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="79"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="162" mass="18520" checksum="8FA1E6046FADCA46" modified="2015-04-01" version="1">MKIFYKYMDSIVGKLKLVAQNHVLIAILWEHEKLNRVKLNELIEDISHPLLVEAEKQLLEYFNKKRKFFELPLEHHGTPFQSKVWEALKHIPYGTTLSYGQLAKEINHPRAVRALGAAIGRNPLSIVIPCHRVIGTNGKLTGFAGGLEAKRTLLKIEDFPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSV1</accession>
    <name>A0A0C1HSV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_DB00200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383364.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77113">
        <property type="protein sequence ID" value="KIC77113"/>
        <property type="gene ID" value="DB41_DB00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0742">SOS response</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="11">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="10">
        <location>
            <begin position="84"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC77113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="23556" checksum="A6664B27F1C442E0" modified="2015-04-01" version="1">MKSLTKKQYELLSYIKTYLQTHHYAPSYREIMQHFSFSSLGTVYKYITILKSKGLLESKKKSSRSLSLLHDYPTKKNFSSLSLPFIGYISAGEPIETFPRSLSFEVPSSLVTMPEATYILKVRGDSLVEELLADGDYLVVEARQEVQAGETVLALLNQNDVIIKKYFLEDVYVRLVSRSLHNHPVILREEDIMVQGVVVAVIRKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSW5</accession>
    <name>A0A0C1HSW5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CY00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000015">
        <property type="protein sequence ID" value="KIC77133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77133">
        <property type="protein sequence ID" value="KIC77133"/>
        <property type="gene ID" value="DB41_CY00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.173"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="60"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="249" mass="28822" checksum="72EC3951B7EC3F7F" modified="2015-04-01" version="1">MMTIVILFHQSNYRNFKHFYHHVNTHMRQEFPKLVSYSRFVYLKKIIFVPLYAYLYSLRGIPTGIAFIDSTSIDVCHNKRITRNKVFKGLAKRGKTTSGWFYGFKLHLIINEKGEVLSFQLPPGNVSDVSIVDILSKDLMGKLFGDKGYLSSQLRQKLINRGLELLTSIRSNMKQKLMSFQDKILLRKRSIIETVNDQLKNIYQIEHTRHRSIGNFLVNMLAGIAAYCHPPKKPSMRFSGQETSFLIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT09</accession>
    <name>A0A0C1HT09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CS00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383213.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77198">
        <property type="protein sequence ID" value="KIC77198"/>
        <property type="gene ID" value="DB41_CS00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="434" mass="48500" checksum="4A215968AEFDCB59" modified="2015-04-01" version="1">MNPTLRSEGSIDPFDWSSLLNSSSSYVTGQATTGNSNQRDNSSLALQNAQSTAVGSQTSLPRTAPDTINTLSDFDWAALGQLTFTDSHLATQLTQQSHNYLGEVAHGKGALSIETHREQMQVVEDMLNDLVQNTKNTTNIIIRAIGDFAQKVQVANHQISNYCLNILKRGMDDPTLTTNDIIKAKLIIEFSATSVGVMKNSSEAAIDLAGKGGGIINQQTLATLKAIFEVRGNQVALLSQKLQVFQQQEQHNLDLILKIQDIKLKEQAQLFNQLKEIIHLREEEKDGNTRRELEVRKAALEAQIQIRGQWLKEEEANNKYQLEAATISNKYQIDKEALRNAREIEEQLTAIKAAEQKDAAANQKLEIQKKAENEGKRIKYERDTNFHQTNIQGRVASQKNELDAEVQRNQIAASERNEHFKTFASIVKPPCVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT37</accession>
    <name>A0A0C1HT37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77233">
        <property type="protein sequence ID" value="KIC77233"/>
        <property type="gene ID" value="DB41_CO00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6827" checksum="D7EF34FD8B543710" modified="2015-04-01" version="1">MLAKPLTFHLTFTFSSCLLIALKLNPVENLWHYLRGHFWSKRIYRGYKKLEKMAINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JIU8</accession>
    <name>A0A0C1JIU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BO00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000235">
        <property type="protein sequence ID" value="KIC71310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039387019.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000235.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71310">
        <property type="protein sequence ID" value="KIC71310"/>
        <property type="gene ID" value="DB41_BO00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8105" checksum="FBCE5ABC19DED2A1" modified="2015-04-01" version="1">MLFIRHANKSYTFNPDLMQLMPNDHQDSQAPALQEDNHHQKVELQVDTDSPTTASTEYGLQIFGFYIYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJY0</accession>
    <name>A0A0C1JJY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386943.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71595">
        <property type="protein sequence ID" value="KIC71595"/>
        <property type="gene ID" value="DB41_AV00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5583" checksum="F93BF49C07A1B158" modified="2015-04-01" version="1">MNEYNNERTYTGKHCFGKTPLQAFLDAKHLAQEKMLDKLQLTEIVSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLG9</accession>
    <name>A0A0C1JLG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72105">
        <property type="protein sequence ID" value="KIC72105"/>
        <property type="gene ID" value="DB41_KU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="6240" checksum="DD94314E06A0BB94" modified="2015-04-01" version="1" fragment="single">KLSIEAEEIGCILFPWVGMTFQHFYFFKNNIKKIKKASQANWYPYQGKIARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM12</accession>
    <name>A0A0C1JM12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_KO00030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386434.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72315">
        <property type="protein sequence ID" value="KIC72315"/>
        <property type="gene ID" value="DB41_KO00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1981"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC72315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="254" mass="29297" checksum="63455575368F5BB2" modified="2015-04-01" version="1">MQRRECHGISWLEFELLAPFKNLTHGILLRHGGYSTDLFASLNMGFSLQNLLENKNVKLNREKVKKIFAFKNLYDCQLEHADKIVEITHKNKGLRPTCDALSTVLHDTVLMITHADCQATIFYDPVQQAIANVHAGWKGNVQNIYGKTVNFMKHHYGSFPDNLHVCISPSLGPYDAEFIHYRQELPPAFWEFQMSPCYFDLWTIAKNQLMQAGVLEHHIQIAQISNFSHPEDYFSYRREKITGRHGTFVAIKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM88</accession>
    <name>A0A0C1JM88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF2 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71651">
        <property type="protein sequence ID" value="KIC71651"/>
        <property type="gene ID" value="DB41_AS00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2208"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="294" mass="33915" checksum="45B2B2EE8BBD4A6C" modified="2015-04-01" version="1">MLDAFKIILQIFPIKRKVWLIIDRTNWQVGSKNINILTLAMAYEGTAIPLAWFVMNKAGNSSTDERIELLEKVIRQLGPSKIAGLIGDREFIGSQWFDYLIKSEIPFYMRIREDTLVEGARNGYAVSLRDVFRHLKEGKKKVLVQPLQMLGHSFYVAASRLKDELLLVVTNKNPKKAISIYKTRWEIETLFACLKTRGFCLEDTHLTYTDRIEKLIFALSIAFCWAYKLGNIAANVVPISIKKHGRKAKSLFRYGLDKIRKILLGTPRCFNLFLWLLKLFDPLLSSSIPKRVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JME3</accession>
    <name>A0A0C1JME3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AN00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000211">
        <property type="protein sequence ID" value="KIC71731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71731">
        <property type="protein sequence ID" value="KIC71731"/>
        <property type="gene ID" value="DB41_AN00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2183"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="550" mass="62247" checksum="27C9B4A32FA4CEFF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMP9</accession>
    <name>A0A0C1JMP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KJ00150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244052.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72540">
        <property type="protein sequence ID" value="KIC72540"/>
        <property type="gene ID" value="DB41_KJ00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1934"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="332" mass="37787" checksum="8426F50B8CBB1D4C" modified="2015-04-01" version="1">MHSISSASIESLPNELLLPILEACVVPSLFSVCKRWHHLLASEVMPPLYKKIAQLHFPTKNTSTQRTLMLAKVYQLNPGLTSTEKVYQVFKQVFTLAKSISPLEFKEKTEEKKGLTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEKKGELLREWIEENCKNITALGLYRVGLTYLPPEIGQLSQLQRLDLSDNQLTALPAEIGQLFQLQWLELNQNQLTSLPAETGQLSQLQWLYLNQNQLTSLPAEIGQLSQLQWLNLSQNQLTNLSAEIGQLSQLQGLKLSQNQLTSLPAEIGQLSQLIMLELAENPLKDIPEKVRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMS8</accession>
    <name>A0A0C1JMS8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_KI00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72565">
        <property type="protein sequence ID" value="KIC72565"/>
        <property type="gene ID" value="DB41_KI00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1901"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="443"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="496"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="645" mass="70361" checksum="6A1CA6EC44258803" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN51</accession>
    <name>A0A0C1JN51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AC00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386603.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000203.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71986">
        <property type="protein sequence ID" value="KIC71986"/>
        <property type="gene ID" value="DB41_AC00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2106"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="184"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="207"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="232"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="282"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="310"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="333"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="357"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="428" mass="47954" checksum="340DD0BC7E05C3E5" modified="2015-04-01" version="1">MQINLSSKACRFIDHKADYVPIISTVTNLVCIFQKVFIIPFKQEKNISKCPYYSYLNGKSFGRCIILLIPVLGNILVGIGDFACKRESDKDALPKPAKYYGGISKHEGQPSRDDKKIFPLTLKKEGVELKNFKEKLQISAQQKVNTLRDASKDHQNDREGVLAAIQYDDLALQQTCQDFQDAKKVVFAAVQHDGLALQYANHALQNNKEVVLAAVQHAGLALQYASPELRNNKEIVLAAVRHAGLALQYASPELRNDKEVVLAAVRHAGLALQYASQELQNDEEVVLVAVQQDCLALRYASQELQNNRVIILAAVQQAPWGLKYVSKELQNEREIVLAAVQKFGLSFRYASQELQNDREILLAAVRRRGSVLMYASKTLKNDREIVLAAIQQDGLALRYASEELQNNPELVDLSFELFRQQSKGSFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JND3</accession>
    <name>A0A0C1JND3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_AA00270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244085.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72046">
        <property type="protein sequence ID" value="KIC72046"/>
        <property type="gene ID" value="DB41_AA00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2098"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="11"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="598" mass="67117" checksum="DC92277B3C85C075" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNZ7</accession>
    <name>A0A0C1JNZ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpoD</name>
        <name evidence="6" type="synonym">sigA</name>
        <name evidence="10" type="ORF">DB41_KQ00210</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386496.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72256">
        <property type="protein sequence ID" value="KIC72256"/>
        <property type="gene ID" value="DB41_KQ00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2028"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="340"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="509"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="316"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="395"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="484"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="340"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC72256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="554" mass="64481" checksum="411BAA108A73A993" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVP0</accession>
    <name>A0A0C1JVP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75110">
        <property type="protein sequence ID" value="KIC75110"/>
        <property type="gene ID" value="DB41_HW00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6439" checksum="8F1C47E0ACF135F0" modified="2015-04-01" version="1">MKKITPSFILTTYKACSLAPLQLIWPLNPPLIGCLNDVFKLHAKTEVFLTASLPKQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVR4</accession>
    <name>A0A0C1JVR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HU00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000131">
        <property type="protein sequence ID" value="KIC75145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75145">
        <property type="protein sequence ID" value="KIC75145"/>
        <property type="gene ID" value="DB41_HU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="3"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="152" mass="17206" checksum="47813209C24E2B3D" modified="2015-04-01" version="1" fragment="single">KVEKKYEFGCKASLVITHQEGLTLDLRAIHGNPYDGHTLEEAIKNAQNNSGKNIEVAFVDKGYRGHTVEGKTIFISGQRKGLTKWIKTQIKRRQAIEPHIGHMKNDGKLGRNHLKGLWGDRYNAILCGIGHNMRLIYNWLVAQTSPKRLYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW09</accession>
    <name>A0A0C1JW09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BH00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000228">
        <property type="protein sequence ID" value="KIC71427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71427">
        <property type="protein sequence ID" value="KIC71427"/>
        <property type="gene ID" value="DB41_BH00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="272" mass="30972" checksum="296EB05073D717DE" modified="2015-04-01" version="1" fragment="single">MPSLCKKIAQLHFPRGDVPTQQTLMLAKVYQLNHVPTSTEKVYLSFKEVFTLAKSISPLEFKEKTEEKRGLTLTNYSSYLLNVNRLLLWKKLPDGEEYLSREEIKHLPLEKKGELLRDWIEENCKNITALDLSRTGLTYLPSEISQLSQLQTLDLRENQLTALPTEIGQLSQLKGLYLNQNQLTSLPAEIGQVSQLQGLYLTQNQLTSLPAEIGLLSKLQKLYLDQNQLTSLPAEIGQLSQLQLLNLNQNQLTSLPAEIGQLSQLKWLYLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW33</accession>
    <name>A0A0C1JW33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BE00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000225">
        <property type="protein sequence ID" value="KIC71452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244126.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000225.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71452">
        <property type="protein sequence ID" value="KIC71452"/>
        <property type="gene ID" value="DB41_BE00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2285"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="314" mass="35886" checksum="D0601F8645447A02" modified="2015-04-01" version="1">MHPISSTSIESLPNELLLPILEACVVPSLFSVCKRWHHLMASEVMPSLYKQIGKVHVPQGNVKEQALIVDRIYKLEEKLSEAEKVNAIFRQIFTLAKSFSPLEFKWKTEEKRGLTLANYSSYLVNMNRLLLWKKLPGGEEYLSREEIKHLPLEKKGELLRDWIEENCKNLTSLNLSGAGFTYLPPEICQLSRLQTLDLSENQLTSLPAEIGQLSQLQMLKLNQNQLTTLPAEIGQLSELTRLYLNQNQLTALPAEIGQLSKLQRLYLNQNQLTSLSVEAVEELKHCAKKSCFSQIRQRIHLILLAKPKLPRHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWQ8</accession>
    <name>A0A0C1JWQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385602.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74871">
        <property type="protein sequence ID" value="KIC74871"/>
        <property type="gene ID" value="DB41_IB00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="138"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="789" mass="90605" checksum="3DF7B34A12284243" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWR2</accession>
    <name>A0A0C1JWR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase (ATP)</fullName>
            <ecNumber evidence="1">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lig</name>
        <name evidence="7" type="ORF">DB41_IB00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385609.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74876">
        <property type="protein sequence ID" value="KIC74876"/>
        <property type="gene ID" value="DB41_IB00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1441"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026333">
        <property type="entry name" value="ATP_dep_DNA_lig_pp_1105_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="SSF117018"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04120">
        <property type="entry name" value="DNA_lig_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="6">
        <location>
            <begin position="306"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="530" mass="61330" checksum="BC36032DC79FE553" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX45</accession>
    <name>A0A0C1JX45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74996">
        <property type="protein sequence ID" value="KIC74996"/>
        <property type="gene ID" value="DB41_HY00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6623" checksum="157A6BEC1B01B6F9" modified="2015-04-01" version="1">MSKMIWLHFFILFSKIVGLPNNFSNASARQLSDSVANPMIIELTKSVKTAYRDGVYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXF5</accession>
    <name>A0A0C1JXF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsB</name>
        <name evidence="8" type="ORF">DB41_AE00020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386639.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71927">
        <property type="protein sequence ID" value="KIC71927"/>
        <property type="gene ID" value="DB41_AE00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2118"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="236"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC71927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="271" mass="30243" checksum="1DE146212EBFCB5B" modified="2015-04-01" version="1">MATQQQVNVTIKDLLEAGAHFGHQTRRWNPKMKRFIFEARNGLYIIDLAKTLQQIRLATEVVKEVVAKHRSILFVGTKKQAKVVVRELAEQAGEFYVCERWLGGMLTNMSTIRQSIKKLERIEKRITSGGEGLTKKELSLLNKDYTKLNSNLSGIRGMRKLPGLVIVVDPSKEHIAVAEANKLGIPVMGLVDTNCNPDPIEYVIACNDDALKSVKLIIQALAHAIIEKKNEMQIAFGKGDVKEDEENEEGVSGKYDEKDEADEKASAISEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXG5</accession>
    <name>A0A0C1JXG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HG00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385179.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75765">
        <property type="protein sequence ID" value="KIC75765"/>
        <property type="gene ID" value="DB41_HG00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="149" mass="16713" checksum="433774438DBDFC01" modified="2015-04-01" version="1">MFPSPTIHGGMNTTHHPALLDNKPPFQAQLNFKILSLTPIIGKFVTKYILKTIDKELQEVNLDNNLRRNSLYDLRVYYSKIEQYHDSSLLSNLVSLVAIVALVTLVASKIIFIAATCLVAGTVFGVLMAATLRQVKWIDQSIKQINQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXX3</accession>
    <name>A0A0C1JXX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HS00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75306">
        <property type="protein sequence ID" value="KIC75306"/>
        <property type="gene ID" value="DB41_HS00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4663" checksum="A17B98FE457D6036" modified="2015-04-01" version="1">MRLSIKFSSPSFSEKLVSIFLCKLFFHPFLSHKFFCKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY20</accession>
    <name>A0A0C1JY20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB</fullName>
            <ecNumber evidence="11">2.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mtaB</name>
        <name evidence="11" type="ORF">DB41_HO00040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75356">
        <property type="protein sequence ID" value="KIC75356"/>
        <property type="gene ID" value="DB41_HO00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1305"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006467">
        <property type="entry name" value="MiaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01579">
        <property type="entry name" value="MiaB-like-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="37"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="158"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="463" mass="52209" checksum="39FAA308CCBCCC75" modified="2015-04-01" version="1">MKNSIVSSFFFRGSNFSLLSALFYIYFSFIILCMVEKKFKIVTLGCRTNQYESQAYHDQLQAMGYSEAAKHEQAEICIINTCTVTESADSSSRHEIRQVARDNPGSKLIITGCFAERQPELVGSLQGVTHVVPNKDKEKLLESVFPAAELPEFSIKRFEAHTRAFVKVQDGCNSFCTYCIIPYVRGRSRSRSLDEIVKEAKGLIANGYKEIVLTGINIGDFDGAKPENEKPDRLADLVRAVDRLPGLERLRVSSIDPDEVDDDLADAILNGMHTCHSMHIVLQAGSNVILKRMNRKYTRQIFLNTVERLKSASADFTFTTDVIVGFPGETDSDFAETLEVMKQVKFAKVHMFPYSERARTRAALMPNKIPQEIIKKRKHEVLRTAEQISFELREQFIGRRMKILTENIDPSRPGEICGHTENFLMVWVPRSDHAPNAILEVELIANTPDGLIGRLSCRQASCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZD4</accession>
    <name>A0A0C1JZD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HD00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000114">
        <property type="protein sequence ID" value="KIC75821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385063.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000114.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75821">
        <property type="protein sequence ID" value="KIC75821"/>
        <property type="gene ID" value="DB41_HD00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="3">
        <location>
            <begin position="34"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="2">
        <location>
            <begin position="191"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="434" mass="49307" checksum="E44AF736F4D587C8" modified="2015-04-01" version="1" fragment="single">MQPSYEQLFKENAELRAEIIQLRAENAQPKALVNRLEKIITKLEARIAQLEAQLNQNSKNSSKPPSTDQKTNRSSSPKAENRPYHPGASRQLLPASVVTSHEVRNVEVCPHCHSAMQATDKVLSWQQIELPEIKPLVHQIDLVTSRCPCCHLETRPELKEKEQFLLGPRLEGFINLLMGQYRQGHRAVRTMISALLPNVALSQGLISKVKARTAALLVSSYETLVKAAITTQQPLHLDATSWRHAATNEHLLVLRVGNVIAYALRPYQNGATLKALVGQQIHCLVSDRGLAIHQIKVKIKQYCLAHLIRNIQGQAEQPNISLEDTQRLGNLYNTLQELFKDKHRLEKGQISQSTWQQYGYLNWRYIQEELQELGCWSSTKKLRKFCHKLLKQIKHFRAYLTDPAIPMTNNAAEESLRNLVIVRKLCLGSQSIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZG5</accession>
    <name>A0A0C1JZG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_2</name>
        <name evidence="3" type="ORF">DB41_GG00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76405">
        <property type="protein sequence ID" value="KIC76405"/>
        <property type="gene ID" value="DB41_GG00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.897"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="842" mass="93485" checksum="4E2CA968529DD5AE" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZI5</accession>
    <name>A0A0C1JZI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GZ00550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385012.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75891">
        <property type="protein sequence ID" value="KIC75891"/>
        <property type="gene ID" value="DB41_GZ00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="146"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="167"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="226" mass="25640" checksum="F7FDF577ADA5AB38" modified="2015-04-01" version="1">MRTNFLSNTCRFIVNKSDYLPFVSTLTNLAYIFQKAVVLPIKQKESMPKSSYYSHLSQKSFGRCIILLLPVLGNIIVGIYDFAHRKSYNKNTGIEPTQYNNGPSIPANQLLKNDIKIDLTTKEQNDSDLEHTNEAPLFEKVFYQACLELVQKDGLVLKYTPTFRNHKEFVLTAVRQNGLALDYASQELQNDREVVLTAVQQNASAVRYASQELQNDPIIISLATSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZP1</accession>
    <name>A0A0C1JZP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oligopeptide-binding protein OppA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">oppA</name>
        <name evidence="2" type="ORF">DB41_GC00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384527.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76455">
        <property type="protein sequence ID" value="KIC76455"/>
        <property type="gene ID" value="DB41_GC00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="72"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="531" mass="59511" checksum="B650B7DBD78CFC71" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZU2</accession>
    <name>A0A0C1JZU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FZ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000085">
        <property type="protein sequence ID" value="KIC76490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384424.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000085.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76490">
        <property type="protein sequence ID" value="KIC76490"/>
        <property type="gene ID" value="DB41_FZ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7202" checksum="617D8E75F72C001D" modified="2015-04-01" version="1">MVELQQVIFRLKFKQSIRSINRDTGIHRTIIRNLNKVANSSGWLSKDSSIPSENEIHQALVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZX3</accession>
    <name>A0A0C1JZX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GR00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC76001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042240849.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76001">
        <property type="protein sequence ID" value="KIC76001"/>
        <property type="gene ID" value="DB41_GR00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007459">
        <property type="entry name" value="DNA_pol3_chi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036768">
        <property type="entry name" value="PolIII_chi_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04364">
        <property type="entry name" value="DNA_pol3_chi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102400">
        <property type="entry name" value="SSF102400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="16171" checksum="27DD548E7C170CEA" modified="2015-04-01" version="1">MQKPNIIFIPVFSNQQKLGSICHYIQHHFEVGDNVLVVAPNEQATRYIDELLWKFSPESFLPHIASNTPSSEKVVITSVAQNLNQALVLINLCAEVSPIAEHFNVVYELYDQTHPEKLAQSQRRQQIYTSKQFTIVHSAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K064</accession>
    <name>A0A0C1K064_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_FJ00030</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000071">
        <property type="protein sequence ID" value="KIC76590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243846.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000071.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76590">
        <property type="protein sequence ID" value="KIC76590"/>
        <property type="gene ID" value="DB41_FJ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.704"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="18"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="225"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="267"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="309"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="351"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="393"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="435"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="477"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="519"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="645"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="687"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="729"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="771"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="813"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="855"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KIC76590.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="918" mass="102620" checksum="125269FA36FE2AA4" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
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    <name>A0A0C1K0J6_9BACT</name>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="DB41_EY00010"/>
    </dbReference>
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            <dbReference type="EMBL" id="KIC76690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="15933" checksum="B66A324D5A3DF4A5" modified="2015-04-01" version="1">MNTNTLNKSEIDKALKGNWKVIGCQLNGLWLPSAIFENFIYSFPDVEHFKLAWGELTFPNYVGGFPKSDKGRISINIDFLPYQIDLIPHSGPFAEKAFKGIFELDHDILKANFAFPEIERPHFFSAKQGHVYEIWQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
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            </authorList>
            <dbReference type="PubMed" id="25069652"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
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    <name>A0A0C1K0X1_9BACT</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
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                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000090">
        <property type="protein sequence ID" value="KIC76421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76421">
        <property type="protein sequence ID" value="KIC76421"/>
        <property type="gene ID" value="DB41_GE00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="KIC76421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5906" checksum="135F1B368B907880" modified="2015-04-01" version="1">MCKLAAYIHQKMGGVQYICIKILYHQGDRYKFSGRRYIHAARRQPILPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K132</accession>
    <name>A0A0C1K132_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">DB41_ED00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76850">
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        <property type="gene ID" value="DB41_ED00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
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    </dbReference>
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            <begin position="1"/>
            <end position="36"/>
        </location>
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        <location>
            <begin position="76"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="203" mass="22454" checksum="36592476E9CEB46F" modified="2015-04-01" version="1">MAGKIPSAPPPPLLKEAPLQTSMAIPVAPPPPPFLKTTDTTQLVAYKKLASPELSKETVKRPDHDIAEQLMKRRLAMHDPDEEEEGVEEDMESLKDSSQPINLEDNQSLSAVKKEKNYPHEATQVKKGIGSQGQPLDRSALMQQIIEGKKLTSIKPNEKLTKPQPSSPLMEALFKKVEQAKSSSPHSSSSENMAEQEDEEWNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K195</accession>
    <name>A0A0C1K195_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DW00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76890">
        <property type="protein sequence ID" value="KIC76890"/>
        <property type="gene ID" value="DB41_DW00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6674" checksum="8E8BA6B8FDB5599D" modified="2015-04-01" version="1">MQRANDFESMKICIKECLDKNPAFCKILQENSDLQGSNQKLTHTVKMESFFLNFMQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1E6</accession>
    <name>A0A0C1K1E6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluB</name>
        <name evidence="5" type="ORF">DB41_DS00110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383622.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76930">
        <property type="protein sequence ID" value="KIC76930"/>
        <property type="gene ID" value="DB41_DS00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.384"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="236" mass="26543" checksum="13FC56D6DC6FAB67" modified="2015-04-01" version="1">MEKIKNRLSKFLAAAGVASRRGCEEIIFAGRVKVNGDICIIPQTMVGAKDSITVDDEKIKQAEAKVYYLLNKPTGYECTNARHRDTKIVIDLFENIEQRLFTVGRLDKETAGLLLVTNDGHFANQVIHPSQNIQKEYLVKTDQDITDEHLKAIASGTLIEGSFVKPVRVIKVRKGTLKVIIMEGKKREVRHLLEAVGLKVYSLTRIRLGGLILGQLPVGSWRPLTDREKKLIFETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1H1</accession>
    <name>A0A0C1K1H1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Adenylate kinase</fullName>
            <shortName evidence="4">AK</shortName>
            <ecNumber evidence="4 6">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">adk</name>
        <name evidence="8" type="ORF">DB41_FM00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="4 6"/>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76576">
        <property type="protein sequence ID" value="KIC76576"/>
        <property type="gene ID" value="DB41_FM00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.725"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADK_lid" evidence="7">
        <location>
            <begin position="129"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="4">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="61"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="138"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="25155" checksum="65B9D46D776BEA31" modified="2015-04-01" version="1">MEKKLIVILLGPPGSGKGTQTKLLSQTLSLPQISTGDLFREHIKKNTLLGLKAKEYINAGHLVPDDLVLEMVNDRVGLPDCNRGYLLDGVPRTLAQAEKVSTTLLKDVHVIVFKLAVDQEVITKRAVGRLICKQCGAIYNSFFSAPLRAGICDKCGQEALYQREDDRLEVVKERLKVYNEQTMPLEEFYSQRYGVISINGADLPEKVFAELKSHIEAFSPYTKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1M4</accession>
    <name>A0A0C1K1M4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383580.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76975">
        <property type="protein sequence ID" value="KIC76975"/>
        <property type="gene ID" value="DB41_DP00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="221" mass="26293" checksum="0E1206D322BF002E" modified="2015-04-01" version="1">MSVPVRGEYHDLAARADFLKKFTLTFSNPLKLNKDTYNRIKYYAPKALKTHFLFNLEKLYYQLIKKSHPVNYEKYKLMVKDVEKYLKIKQQHLTLLSNNLLVDVQDPWLLAYTQTKNMSLQEASEHLQDLLFSWEELAKYELEDFIPLDLKDLDDYIQKLEEIYRPLLEKSCPVEDKPLENQKLNELADRISTLRDKIEHHNFSEISQLCQNIRATIHVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1P6</accession>
    <name>A0A0C1K1P6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384164.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76606">
        <property type="protein sequence ID" value="KIC76606"/>
        <property type="gene ID" value="DB41_FI00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7607" checksum="F6525CFABFE112F6" modified="2015-04-01" version="1">MKSNKQKQLYDTLAKNHACYVLITCDKPVEDGNMQVQMTYEGDASLVAYLLQGAQSFIDEKEEEAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1V3</accession>
    <name>A0A0C1K1V3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HPr kinase/phosphorylase</fullName>
            <shortName evidence="10">HPrK/P</shortName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
            <ecNumber evidence="10">2.7.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">HPr(Ser) kinase/phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">hprK</name>
        <name evidence="13" type="ORF">DB41_FB00030</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[HPr protein]-L-serine + ATP = [HPr protein]-O-phospho-L-serine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46600"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>[HPr protein]-O-phospho-L-serine + H(+) + phosphate = [HPr protein]-L-serine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:46604"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The Walker A ATP-binding motif also binds Pi and PPi.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the HPrK/P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EC" id="2.7.4.-" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76661">
        <property type="protein sequence ID" value="KIC76661"/>
        <property type="gene ID" value="DB41_FB00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.614"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01918">
        <property type="entry name" value="HprK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01249">
        <property type="entry name" value="HPr_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003755">
        <property type="entry name" value="HPr(Ser)_kin/Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011104">
        <property type="entry name" value="Hpr_kin/Pase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011126">
        <property type="entry name" value="Hpr_kin/Pase_Hpr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF1">
        <property type="entry name" value="PTHR30305:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07475">
        <property type="entry name" value="Hpr_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02603">
        <property type="entry name" value="Hpr_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00679">
        <property type="entry name" value="hpr-ser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hpr_kinase_N" evidence="11">
        <location>
            <begin position="4"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Hpr_kinase_C" evidence="12">
        <location>
            <begin position="133"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of both phosphorylation and dephosphorylation" evidence="10">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of dephosphorylation" evidence="10">
        <location>
            <begin position="267"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity" evidence="10">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="325" mass="36451" checksum="2B713A7B43744BB7" modified="2015-04-01" version="1">MIYKVEELFQKHGHDLGLVLVAGHKGLKRSIKVPESHRPGLSLCGFMKNHAYKRILVFGRVEMEYLRDLDPEIRVNRLKEILTTATPAVIVARRLLPLKELVSLCQNKGISLFRSSMSTMSLLSKLTLLLSEEFSPSMTCHGTLVEVFGVGVLIKGDSSVGKSEAALGLIERGHRLISDDVVKVKKREDSYVEGFGAELTRHHMEIRGIGIINVAHLYGAVCVRDNKSIDIVVKLEAWDDQHFYDRVGLVENYCDLLGLNIPYHVLPVKPGRDVVLLLETIALNHRLKAMGYNSAKEFNNKLLDMISSKNQTRKRIREAVESSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1V8</accession>
    <name>A0A0C1K1V8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76666">
        <property type="protein sequence ID" value="KIC76666"/>
        <property type="gene ID" value="DB41_FB00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4619" checksum="419E9F3DB9CC8486" modified="2015-04-01" version="1">MNVFLSILLALSNFKEGGICAKQKKFLLTFSGWALNLIKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K202</accession>
    <name>A0A0C1K202_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76701">
        <property type="protein sequence ID" value="KIC76701"/>
        <property type="gene ID" value="DB41_EY00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="180" mass="20945" checksum="39C746B057890169" modified="2015-04-01" version="1">MFGKEETMFVASYHTIEELNALSKKKASASYSLKLRAVAMAMEGESASQIGKTLGYCTSAIQKWIRRYNHHGLEGLIDRRPIITGRKRALTPEQEKAFLTRVEKGPEPCELLKVYHLSDLQFILKEEFGKKLTLPGVWGILRRFSYPPLILRLQRYKANPKEQKKLKKFEIHQWIKESFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K272</accession>
    <name>A0A0C1K272_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DB00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77095">
        <property type="protein sequence ID" value="KIC77095"/>
        <property type="gene ID" value="DB41_DB00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.192"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="154" mass="18212" checksum="B3760C9C58B4D7C5" modified="2015-04-01" version="1">MDTQGFLLTCYVGTADENKRAGLIKLLDKCKSLFSTITKVWADIGYQGTLLKQTCHNKYDIGVEIVRRSPRRYWMHKDKIAEFSKTTDLSFKVLPKRWIVERTFAWIGRNRRTSKEYEYLTVKRHDKLTPWRHELLTPTSGRRHQQLTPSHSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2I8</accession>
    <name>A0A0C1K2I8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sod2</name>
        <name evidence="9" type="ORF">DB41_CP00100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383169.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77225">
        <property type="protein sequence ID" value="KIC77225"/>
        <property type="gene ID" value="DB41_CP00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.86"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="99"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="211" mass="24127" checksum="1B7D308B5111457A" modified="2015-04-01" version="1">MAFKYQLPPLPYDFGDLEPVISAEIMNLHYTKHHQTYVNNLNKALEQYEEAQGKAEKSNDPTDLIALQSAIKFNGGGHINHSIFWTNLAPKSQGGGTAPNDDLQNAIKKDFDSWEKFIEEFSARTVAIQGSGWGWLGYCKQHHRLQITTCENQDPLSPKGLIPLLGIDVWEHAYYLQYKNVRAEYVKNIWEIVNWKNVEERYKLASAAKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Y4</accession>
    <name>A0A0C1K2Y4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase subunit 2</fullName>
            <ecNumber evidence="8">1.10.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cydB</name>
        <name evidence="8" type="ORF">DB41_DH00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.-" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383425.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77061">
        <property type="protein sequence ID" value="KIC77061"/>
        <property type="gene ID" value="DB41_DH00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.244"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC77061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="343" mass="38025" checksum="080CC355EA36BD13" modified="2015-04-01" version="1">MIALENLQVIWFMVFVILLTGYAILDGFDLGVGMMHLWGANDYERRIILNSIAPVWDGNGVWLVTAGGALFAGFPQVYATLCSAFYTPIMILLTGLIFRAVAIEFRSKQPMAWWRWTWDSMFTLASVIISLTLGITIGNLIVGIPLDENGEFIGTFQTLLHPYALLVGMMTLALFMMHGAIYLVMKTEGSLHDRLRQKVNPAIIFFIILYAIATVATLIYFPHMAESVKNRKDLFIIAVINMLLIANIPREISKGRDGWAFLSSCGNIICLMGLYGAGTYPAVVRAVNDPQALSLTIYNSSSSAKTLEILLLIAVIGVPLVIAYTIVIYKVFYGKVKLDPTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K333</accession>
    <name>A0A0C1K333_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">pgk</name>
        <name evidence="12" type="ORF">DB41_DB00080</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383349.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77101">
        <property type="protein sequence ID" value="KIC77101"/>
        <property type="gene ID" value="DB41_DB00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.199"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="22"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="61"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="356"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC77101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="410" mass="44532" checksum="0C6BA9ED572459D6" modified="2015-04-01" version="1">MLTKLSLKNLQVAGKKILMRVDFNVPLDPLGQIIDDTRIQASLPSIEYILKQGGSVILMSHLGRPKGQKVPNFSLLPCAKHLSMLIERPVHMALDCVGKSVEEQVQKLGACQVMLLENLRFHHAEEYPEHNFSFAQQLSKLGDAYVDDAFGTAHRKHTSTYYLPKLFPQEAAMGFLMEKEILSLEKFIGDSKKPFCAIIGGAKISTKIGLLKTLLNKVDILLIGGAMAFTFMKAHGYTIGDSLYEPEFLPMAKDILDESRIKGVQVVLPVDHIIAQRLENPANVSIILSKAGIPEGYQGFDIGPLTIQQFSEFIQEAATVFWNGPLGAIEAIKFANGTLAIAEKVAHSAATTVVGGGDSITALQKAGLMEKITHISTGGGASLKFLESGTLPGIEALSSAYRLAKKLSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K386</accession>
    <name>A0A0C1K386_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CR00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383190.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77211">
        <property type="protein sequence ID" value="KIC77211"/>
        <property type="gene ID" value="DB41_CR00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="232" mass="26193" checksum="4A3A3710C1658FC2" modified="2015-04-01" version="1">MKLATDKSHRDYFYKHGTIEFDGLFPLEQIQQLNTAIDGLLSLTFKNIAPQSQNTENVFLCGRDLYRKDERIKKQVLNRRLAEIAQELMEARGLRIGYDQLLVGQSGQANVNTDALYNQFLQSVGSLQDKSCVQPLVCGLVICLQPSSSLEIPPVILPQTLGNGVFFKPDLPLDLSYLSHAQGGRYLMIAYAKPRSIYVLNDKDPHTHSLKHRGYVFGDRLSDKLNSLIIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3A0</accession>
    <name>A0A0C1K3A0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipid II flippase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">murJ</name>
        <name evidence="10" type="ORF">DB41_CO00050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MurJ/MviN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77236">
        <property type="protein sequence ID" value="KIC77236"/>
        <property type="gene ID" value="DB41_CO00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.38"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002869">
        <property type="entry name" value="MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="536" mass="58601" checksum="092B79FBD09E5B4D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3B9</accession>
    <name>A0A0C1K3B9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CL00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000003">
        <property type="protein sequence ID" value="KIC77271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77271">
        <property type="protein sequence ID" value="KIC77271"/>
        <property type="gene ID" value="DB41_CL00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7213" checksum="883A30EC16645B71" modified="2015-04-01" version="1">MHFISLGRDDLLLIFIFKGNIKKLKKQVKRIRILINEKQLTNDLTALFFQIDSRKGGDLPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K4A5</accession>
    <name>A0A0C1K4A5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IT00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386060.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000151.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74142">
        <property type="protein sequence ID" value="KIC74142"/>
        <property type="gene ID" value="DB41_IT00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="10045" checksum="A6CEFDF4E94F1EDB" modified="2015-04-01" version="1">MKHRRLIYLLSLFSFFIPYTLEAYDRIGKNLKIYSYTQPRRPRRHGRQPTSRANSPYPSKFTPHPQRSYRYPPQGFHPSSKYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K4I3</accession>
    <name>A0A0C1K4I3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IR00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386045.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74232">
        <property type="protein sequence ID" value="KIC74232"/>
        <property type="gene ID" value="DB41_IR00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="143" mass="17325" checksum="A941584CCE05A9B9" modified="2015-04-01" version="1">MGCFFFNFNPFNCIDLHPWRLITEAPPSIKTIPEELIVHIFSFLSPQELVDAQQVCKRWRRIGDEETLWKRHHHQHFKDKPLYISLFLRKARTFRNSYLFYSRWELIDRKAKLEAAALRDSPAYNPIFSERLLWMNQSQSFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5L4</accession>
    <name>A0A0C1K5L4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplU</name>
        <name evidence="6" type="ORF">DB41_IJ00430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74572">
        <property type="protein sequence ID" value="KIC74572"/>
        <property type="gene ID" value="DB41_IJ00430"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1623"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15158" checksum="87649605D049FA9F" modified="2015-04-01" version="1">MRYTAYSLLISLKKLYRFTMPKGARMSSNKSYAIIKTGGKQYRVAKDDIIQVEMLDAEPGEKVEFAEVLFVGEENSSHVSAQALEGFKVMGELLDIVAGPKVVSLKYKPSHNNYRKFGHRQHYARVKITEIAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7G1</accession>
    <name>A0A0C1K7G1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">queA</name>
        <name evidence="6" type="ORF">DB41_HW00090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385479.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75097">
        <property type="protein sequence ID" value="KIC75097"/>
        <property type="gene ID" value="DB41_HW00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1365"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="345" mass="38786" checksum="E15B7CB0A46902AD" modified="2015-04-01" version="1">MKDWHSLNNYLYDLPEELIAQYPCEPRDATRLLVVDRASGNMHEMVFHELADFLGKGDSLVFNNTKVLPSRLIGSRSSGGKAEIFLIKRLPTGDWEALVKPGKKLGKGSNVTFNEGFSCKIIDVLADGKRVVNFDYEGDITQALEKFGHVPLPPYMRRAAIPELDKERYQTVYAQHPGSVAAPTAGLHFTDKLLQRLEEKSVQVDKLTLHIGLGTFLPVKVEDIREHQMHDESFEISQETAERLNKRPINKRQICVGTTSCRALEAAASASGMITGGKYNTNIFIHPGYQFKYVQHLLTNFHQPGSSLLMLVSAFASPELIKEAYNKAIKERYRFLSYGDAMLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9C4</accession>
    <name>A0A0C1K9C4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">tpiA</name>
        <name evidence="5" type="ORF">DB41_HG00220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75767">
        <property type="protein sequence ID" value="KIC75767"/>
        <property type="gene ID" value="DB41_HG00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1194"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="32"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="256"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="282" mass="31045" checksum="F4B8B8686ED34FA5" modified="2015-04-01" version="1">MACFLGRKNDNITFKKGIFMTSASRPVVIAGNWKMYKTIEEATAFVPELVSLINTPQAHIYLAVPFTAIKATSEAAKDTVVVVGAQNINDASEGAFTGEIAGKMLKDAGAEFVIIGHSERRRLFYETDDLINKKVKRALQDNLQVIFCVGESKKEREAQQTHEVLARQLKEGLADISVEQLRHIIIAYEPIWAIGMPQPAGAETAQDAHAFCRQLINEGWDEKAAEQIIIQYGGAVKPENAKKFLEQPDIDGLLVGGASLSAKDFAQIINCYNSIYEEGITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9S2</accession>
    <name>A0A0C1K9S2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Biotin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GX00050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BioY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000109">
        <property type="protein sequence ID" value="KIC75907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042240939.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000109.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75907">
        <property type="protein sequence ID" value="KIC75907"/>
        <property type="gene ID" value="DB41_GX00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34295">
        <property type="entry name" value="PTHR34295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02632">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016661">
        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="181" mass="19241" checksum="D3627BC3938A806F" modified="2015-04-01" version="1">MQLAIPSSFTLTDSWPCRLLISLAGSFLIALGAKVSLTLPFSPVPFTCQTLAVLFLGITLGSRQAAAATLLYLLEGTCGLPVFSPLIAQPLILIGPKAGYLLAMPLQAYLAGKASSQKSMQDNLVILTLACLLVLALGASILAIFVGGKNAIYMGLYPFLFSEVLKIFIAMGYLNSRKIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAY5</accession>
    <name>A0A0C1KAY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_GK00060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384665.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76292">
        <property type="protein sequence ID" value="KIC76292"/>
        <property type="gene ID" value="DB41_GK00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.914"/>
    <dbReference type="UniPathway" id="UPA00997"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="300" mass="31964" checksum="0F795FFE6B35C209" modified="2015-04-01" version="1">MLKIDLRGKKAFIAGIGDDQGYGWAIAKSLAEAGAEILIGTWTPMMRMFCNNLASGKFDESRVLSDGSLMQIAKIYSLDASFDSMDDVPEEIKENKRYKEATEYTISDVAESIRKDYGKIDIFVHSLANGPEVQKSLLDTSRKGYLAAISASSYSFVSLLAHLGPLINAGGATLSLTYIASEKAIPGYGGGMSSAKAALESDTRTLAWEAGRKWNIRVNTISAGPLRSRAAKAIGFIERMIDYSEANAPLAKSLQATEVGNVGAFLLSPLASAITGSLIYVDNGLHSMGVAVDSPTLSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB83</accession>
    <name>A0A0C1KB83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">zwf</name>
        <name evidence="9" type="ORF">DB41_GG00100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384613.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76402">
        <property type="protein sequence ID" value="KIC76402"/>
        <property type="gene ID" value="DB41_GG00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.894"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="32"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="221"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="521" mass="59661" checksum="6804D5157DF4EA64" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB96</accession>
    <name>A0A0C1KB96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GE00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000090">
        <property type="protein sequence ID" value="KIC76422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384583.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000090.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76422">
        <property type="protein sequence ID" value="KIC76422"/>
        <property type="gene ID" value="DB41_GE00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="15936" checksum="EF1AB48BD3371A79" modified="2015-04-01" version="1">MGVDVLKGEVFYKIVAPSLEEEMVKQKATSLGISEIKTLEEKNLLINSLLHDIQSKISDYINKEEVLNKNKHLKHYKSPSLYKWSVLEQAEKAVETIYPYATDENLTLSGKSSKQPADKSLPITPLLLLCSVVAMTILGKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBX1</accession>
    <name>A0A0C1KBX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76597">
        <property type="protein sequence ID" value="KIC76597"/>
        <property type="gene ID" value="DB41_FI00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="19505" checksum="D1CAE221C4F4AB6B" modified="2015-04-01" version="1">MRDEGLLEQLAKGVYRLTEIPDFSEPDLVLIYKKIPQGIICLISALAYYEITTQIPHFVYVALPPKSRKSRLDYPPIRYFYYSEKAYNEGLETTLIGGYPIKIYNIEKTLADCIKFRNKIGRGVVIEALKMYWQRKNTQIDRLYEYAKLNRVEKILHPMMETIVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC39</accession>
    <name>A0A0C1KC39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphocarrier protein HPr</fullName>
            <ecNumber evidence="2">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ptsH</name>
        <name evidence="2" type="ORF">DB41_FB00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384027.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76662">
        <property type="protein sequence ID" value="KIC76662"/>
        <property type="gene ID" value="DB41_FB00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.615"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="10009" checksum="06C62DE72736FD40" modified="2015-04-01" version="1">MKLSSQVQVKNKMGLHTRPATVIVKLLQNSKSDVTFKHKKEEINAKSILSILMLAARRNSKITIEVVGEDAKETLERLVQAFENQFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC49</accession>
    <name>A0A0C1KC49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphoglucomutase</fullName>
            <ecNumber evidence="10">5.4.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pgcA</name>
        <name evidence="10" type="ORF">DB41_FB00140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243823.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76672">
        <property type="protein sequence ID" value="KIC76672"/>
        <property type="gene ID" value="DB41_FB00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.626"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="7">
        <location>
            <begin position="54"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="8">
        <location>
            <begin position="232"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="9">
        <location>
            <begin position="333"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="6">
        <location>
            <begin position="529"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="601" mass="67705" checksum="F487C95093359BAF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCM0</accession>
    <name>A0A0C1KCM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EH00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76827">
        <property type="protein sequence ID" value="KIC76827"/>
        <property type="gene ID" value="DB41_EH00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="10273" checksum="BA1C6B5ED1BEE055" modified="2015-04-01" version="1">MPSILYPGIGKEVKLSKTFAISRIQKSIYLIPTAYLHSWKVKKRKALFFNRHNDKYFMSRLAPPWQLFLRVLACYPSCKKFRFLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDC4</accession>
    <name>A0A0C1KDC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383525.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77012">
        <property type="protein sequence ID" value="KIC77012"/>
        <property type="gene ID" value="DB41_DN00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="517" mass="59578" checksum="4C676B973473788C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDS7</accession>
    <name>A0A0C1KDS7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">engB</name>
        <name evidence="10" type="ORF">DB41_CZ00080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77127">
        <property type="protein sequence ID" value="KIC77127"/>
        <property type="gene ID" value="DB41_CZ00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.182"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="9">
        <location>
            <begin position="31"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="163" mass="18555" checksum="C6A82D45CB1E3557" modified="2015-04-01" version="1">MNAYAFAKARFIKTAMGPKDYPILKDDGGNLLPEVAVAGRSNVGKSSLLNHLFGSKGLVKTSSVPGKTQALNFFVIDEKLVFVDLPGYGYAQVPLSTRKLWGPMVERYLKEREPLKLILFLFDIRRMPNEDDRRFLEWVIHYQKAMILVFTKVDKISTNEKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1U1</accession>
    <name>A0A0C1H1U1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AS00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71654">
        <property type="protein sequence ID" value="KIC71654"/>
        <property type="gene ID" value="DB41_AS00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7189" checksum="A6586CCF13B9386E" modified="2015-04-01" version="1">MRLINNWLIAQNSPKRLYSGYKSSLSFLIDCFIILSGRLPAALKLLNFSQFSSSSTKILGFAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H208</accession>
    <name>A0A0C1H208_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AP00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000212">
        <property type="protein sequence ID" value="KIC71724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71724">
        <property type="protein sequence ID" value="KIC71724"/>
        <property type="gene ID" value="DB41_AP00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6846" checksum="041B83C90BBD7A0A" modified="2015-04-01" version="1">MHQKKPFFSNKAKNQSHSFSRTKIAASLNRKNLWLLLNTWKVSPLSVNLSEKKALLDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H214</accession>
    <name>A0A0C1H214_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AN00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000211">
        <property type="protein sequence ID" value="KIC71729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71729">
        <property type="protein sequence ID" value="KIC71729"/>
        <property type="gene ID" value="DB41_AN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="196" mass="22654" checksum="AB62113FC364D43B" modified="2015-04-01" version="1">MVTYLTFFLVQVFSHLKMFVKTPCQSNTLLYWSKFLELPSSLLLFSHLNPNASNEERSIALIDHDFKVNRRNWKTIATSLMKLAKGELTEQIIKNLKTSINIRLNNDPAAAETYQEQLNQQGKTIKKCLEQGFHRGAQNLLQACREPEALSSLLEVSSSSNLSFPKEEFSDRVQIFTELLKIVKNIIARRKNEWTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3Z6</accession>
    <name>A0A0C1H3Z6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KQ00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72259">
        <property type="protein sequence ID" value="KIC72259"/>
        <property type="gene ID" value="DB41_KQ00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5676" checksum="B349C960A8C5C422" modified="2015-04-01" version="1">MSRCSFFPSFLPYSKVRKRFLSQKLVSKGRKIEAFLYYSWDRRGPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4W2</accession>
    <name>A0A0C1H4W2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KJ00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72539">
        <property type="protein sequence ID" value="KIC72539"/>
        <property type="gene ID" value="DB41_KJ00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7756" checksum="9AF626D90881281E" modified="2015-04-01" version="1">MFADKSYISHQLFIKLDDKGLEIITKLSRLMSLVGKILSRKRGIIERLNNKLKNSCQIEHHRHRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4Z5</accession>
    <name>A0A0C1H4Z5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YbbC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ybbC</name>
        <name evidence="2" type="ORF">DB41_KI00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386336.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72559">
        <property type="protein sequence ID" value="KIC72559"/>
        <property type="gene ID" value="DB41_KI00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1895"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033922">
        <property type="term" value="F:peptidoglycan beta-N-acetylmuramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008302">
        <property type="entry name" value="NamZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42915">
        <property type="entry name" value="PTHR42915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07075">
        <property type="entry name" value="DUF1343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016719">
        <property type="entry name" value="UCP016719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002150989" evidence="1">
        <location>
            <begin position="21"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="419" mass="47911" checksum="4163BC96C44EC6FE" modified="2015-04-01" version="1">MRYFLSLTILVNFLVNYLQAAPTPQVQVGADLLFTKEYVHLLKNKRIGLITNHTAVNSQMKSTASLLQSHAKQYDFTLAALFAPEHGITGSAHAAEFIKDEKDSAGIPIFSLHGATRRPTDKMLAQLDLLLYDIQDIGSRSYTYITTLFYVMEEAAKRQIPVIVLDRPNPINGRVIDGPLLEEKWRSIVGYINVPYCHGMTVGELARYFNDQSKVGCQLEVIPMRGWHRNMTFQDTGLPWIPTSPYIPEATTAYYYPVTGILGELQIVNTGIGYTLPFKVLGAPWIDAKIFAHHLNSQKFPGVYFEPFYYRPFYGRFANEECKGVIIIITNHLIYKPVSTQYLLIGILKSLYPKEFKEALANSQDRKAMFCKVNGTDKVYQIIKEEKNIVWKLRSFHEKERKAFAHQRKKYLISSYAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H589</accession>
    <name>A0A0C1H589_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KH00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000188">
        <property type="protein sequence ID" value="KIC72619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72619">
        <property type="protein sequence ID" value="KIC72619"/>
        <property type="gene ID" value="DB41_KH00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="192" mass="22124" checksum="A036945F7CD65351" modified="2015-04-01" version="1" fragment="single">QVMMLWNNGSKREYRVWNAKNGTKIYEGELEPLPSDKYLKKKQVKLTVCDYNQSQLVVGFSDGTIACYESANGKFIREKLMTFRAIRFLQVGKEYCITAANLDFFFEVHPLSFTDLDGKHLYVKRPGKAKEVIAKLRSFYSNKRSLASCDTDGWLEQWDFDGIISQKKGSISQDKDKNERPFSFGLPSFLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5Q7</accession>
    <name>A0A0C1H5Q7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KC00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386278.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000184.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72819">
        <property type="protein sequence ID" value="KIC72819"/>
        <property type="gene ID" value="DB41_KC00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012872">
        <property type="entry name" value="DUF1670"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07900">
        <property type="entry name" value="DUF1670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="293" mass="34009" checksum="8C48798327287EEE" modified="2015-04-01" version="1">MKNVTINSREDQERRLQIKNIHQQMKNLAVQGTGISPWEAQILVGLIEEVYFSELNQNHLKPGQIKYHCVAAEEGAGKSLKECKMLPVVLTLFDQRDKGNFSQDNNKDKSVELRRRRLVRIAEEAKEQGGYLTQEDLAELLMCDIRTIRRDIKELRTIGILLPTRGQQKDIGPGVSHRAIAIRLWLEGKEPVAIAQHIKHSIEAVENYLQKFKRVAFLKSKHFNEFEIALTVGISIYATKTFSLLYEEFKDKAFFEQRLEEVYIVGAQYYHAQDEKKRMMPSNDSIRNERRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6H3</accession>
    <name>A0A0C1H6H3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JT00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000176">
        <property type="protein sequence ID" value="KIC73069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73069">
        <property type="protein sequence ID" value="KIC73069"/>
        <property type="gene ID" value="DB41_JT00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8198" checksum="8FDE684DD895E97C" modified="2015-04-01" version="1" fragment="single">NRYSHEMLRISGTEGKAPKEAVWKTPEAERLVKAQLEGLTKNLSELTIETQASLKGLFEKLNLQKEVELYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H968</accession>
    <name>A0A0C1H968_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BH00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000228">
        <property type="protein sequence ID" value="KIC71428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71428">
        <property type="protein sequence ID" value="KIC71428"/>
        <property type="gene ID" value="DB41_BH00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7711" checksum="266EBFAE8CD6FD46" modified="2015-04-01" version="1" fragment="single">GLYLNQNQLTALPAEIGQLSRLLWLELNQNQLTALPAEIGQLSDLQTLELAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9P9</accession>
    <name>A0A0C1H9P9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IU00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000152">
        <property type="protein sequence ID" value="KIC74069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386065.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000152.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74069">
        <property type="protein sequence ID" value="KIC74069"/>
        <property type="gene ID" value="DB41_IU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="3">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="2">
        <location>
            <begin position="166"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="444" mass="50643" checksum="9F727CD4BCE3086B" modified="2015-04-01" version="1">MNRLEKIITKLEARIAQLEAQLNQNSKNSSKPPSTDQKANRSSLPKAENRPYHPGASRQLLPASAVPSHEVRCLKVCPHCHSAMHATDKVLSWQQIELPEIRPLVHQIDLVTSRCPCCHLETRPELKENEQFLLGPRLEGFINLLMGQYRQGHRAVRPMISALLPNVTLSQGFISKVKARTAALLFSSYETLVKAVITTKQPLQLDATSWRHAATNEHLLVLRVGNVIAYALRPYQNGATLKALVGQEIHCLVSDRGLAIHQIKVKIKQYYLAHLPRNIQGQAEQPNISLEDTQRLGHLYDTLQELFKDKHRLEKALISQSTWQQYGYLNWRYIQEELQELQCWSSTKKLRKFCYKLLKQIKHFRAYLKDPAIPMTNNAAEESLRNLVIARKLCLGSQSTYGKRWREALHSCIETLYRQGKSILDFLAAAILAARTKQPIPSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAW2</accession>
    <name>A0A0C1HAW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative deoxyribonuclease YabD</fullName>
            <ecNumber evidence="1">3.1.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yabD</name>
        <name evidence="1" type="ORF">DB41_AE00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.-" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386648.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71933">
        <property type="protein sequence ID" value="KIC71933"/>
        <property type="gene ID" value="DB41_AE00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2125"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="29731" checksum="A2EC73DF84287585" modified="2015-04-01" version="1">MANALQWIDSHAHLTDSTFTAVDSLLQRAQHAGVRSVINICTSISTLNAGLELAKNYPWIYNAAATPPHDVEKEGENVFAVIARHARKGHLVAIGETGLDYHYYASSSAIQKDFLRRYFHLALECKLPVVIHCRNAFKDFFEILDKEYMSSNGKHHPGVLHCFTGTIEEAEQVIERGWYLSISGILTFKNSEELRQIVKRIPLEKLLIETDAPYLAPQTQRGKINEPAYIVETAQTIAQLKAISLKELADQTVRNACELFKIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAW9</accession>
    <name>A0A0C1HAW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71938">
        <property type="protein sequence ID" value="KIC71938"/>
        <property type="gene ID" value="DB41_AE00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6463" checksum="71CF2AB70A62F093" modified="2015-04-01" version="1">MIKSQMALSPQFLMNFLKAYRAYTLLKHFLCSSVLYKSPFLKERDSLQRVKYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB55</accession>
    <name>A0A0C1HB55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyrazinamidase/nicotinamidase</fullName>
            <ecNumber evidence="2">3.5.1.-</ecNumber>
            <ecNumber evidence="2">3.5.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pncA</name>
        <name evidence="2" type="ORF">DB41_II00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.-" evidence="2"/>
    <dbReference type="EC" id="3.5.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385903.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000142.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74619">
        <property type="protein sequence ID" value="KIC74619"/>
        <property type="gene ID" value="DB41_II00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1570"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="23743" checksum="FCE7ECFDE3614892" modified="2015-04-01" version="1">MTALLIIDVQNDFFPPGALAIKDAEKILPNLNKIIRHPFEIIVATKDWHPLGHVSFASSHGKEVGEVIHLDGLEQVLWPIHCVQDSVGAQFSAGWDSHRVQKVIYKGTDKRMDSYSAFFDNGRSKATDLHNFLQSKGIKKIFLVGLATEYCVKYSALDALNLNYQVYVIIDACKAVNPLPAAEEKHLNEILQVGGSLIETKEVIKSLTLSYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBE2</accession>
    <name>A0A0C1HBE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KV00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72093">
        <property type="protein sequence ID" value="KIC72093"/>
        <property type="gene ID" value="DB41_KV00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2069"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="60"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="163" mass="19083" checksum="D0173CB87C415C8C" modified="2015-04-01" version="1">MTIVIMFHRSGYRTFKDYYIRQVIPSLKKYFPNILSYHKFITLMKTCLFPIFVYSQACLGECTGISFVDSTLLTVCHTRRIHSHRVFKKIAIRGKTSTGYFYGFKLHLVINDRREILAYMLTPGNVDDRIPVPNLSKNIFGKMFADKGYISRQLFIKLYDKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBV9</accession>
    <name>A0A0C1HBV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74909">
        <property type="protein sequence ID" value="KIC74909"/>
        <property type="gene ID" value="DB41_IB00420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5665" checksum="C6CFD07ED47AFCB8" modified="2015-04-01" version="1">MSGTYSFSSLLINFYFKRKERKTLLVLYKRFSCFPYSSINYLLIPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC07</accession>
    <name>A0A0C1HC07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">rplI</name>
        <name evidence="10" type="ORF">DB41_IB00820</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385768.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74949">
        <property type="protein sequence ID" value="KIC74949"/>
        <property type="gene ID" value="DB41_IB00820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1518"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="8">
        <location>
            <begin position="4"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L9_C" evidence="9">
        <location>
            <begin position="66"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="165" mass="18155" checksum="E2B4A200D03D9C6F" modified="2015-04-01" version="1">MANKLLLLKDIETLGRSGDIVGVKPGYARNFLLPQGMAVVADKKALRMQARLQEERQKKAALDRQESDELAAKLEGQNITTIVKVDHEGHMYGSVSTGDIAELLEQQMSITLDKRTLQLKHAIKVIGVHKISVKLKEGVQASFSLTIEPEGKAVLPKEESVTKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC47</accession>
    <name>A0A0C1HC47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">rplA</name>
        <name evidence="10" type="ORF">DB41_HY00050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385539.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74979">
        <property type="protein sequence ID" value="KIC74979"/>
        <property type="gene ID" value="DB41_HY00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1400"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="232" mass="25054" checksum="99A6ED809C6F100F" modified="2015-04-01" version="1">MGRQSKRIREAAKQVDVTKTYTVKEAVEILKKCPPVKFDQTLDVALKMGVDPRRTDQHVRGTVSLPNGTGKTISILVFARGEKVKEALAAGADYAGDDELLEKVSGGWSGFDAVIATPDMMREVGKLGKVLGPRGLMPTPKAGTVTTDIVKAIHELKAGKIEFKVDRHGMINNGLGKLSFAHDKLEENIMAFLHAVQKSKPAAAKGQFMKSAYLSSTMGPGLKIDLRAIEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD86</accession>
    <name>A0A0C1HD86_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0301 protein DB41_HN00060</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HN00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385351.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75374">
        <property type="protein sequence ID" value="KIC75374"/>
        <property type="gene ID" value="DB41_HN00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1283"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00758">
        <property type="entry name" value="UPF0301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="21111" checksum="12593250AC8B4EDF" modified="2015-04-01" version="1">MEAIPYTQIQKGHFLIASPDIDKGIFFRAVVLICEHNPSGSFGLVINKPLDLELPEEIISVQHLANPRVGIRGGGPVQTNQMMLLHTGKDISHQALQITKDIYLGGDLQFLQDSLNDENGPYIHLCFGYAGWGAGQLERELLDETWFIYPATTKHIFHTPPDKLWQSLLREMGGKYASLSMIPDDLSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE61</accession>
    <name>A0A0C1HE61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JU00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000177">
        <property type="protein sequence ID" value="KIC73028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386226.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000177.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73028">
        <property type="protein sequence ID" value="KIC73028"/>
        <property type="gene ID" value="DB41_JU00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="406" mass="46210" checksum="EBD0A1AFC16926CC" modified="2015-04-01" version="1" fragment="single">MRSYYAHLANASPHSTLKNFSPSIFRSSAIFPVISLPGISARLLFMGYWMLKSHVQEIAAQISLRSSEGELLYRTSLHIREAKTYRIELIDQLIAIGIPLDQPFIGSLEVEFFSTRHLVFPYPAVAINYYGSAFSTVVHSAQRVYNNFEDMRNNSHSHVPEAGFNIYADEDHEPFISIINGPEALHQAPLLMEFYNSKNEKLTHEISYPTLQAYQTCLIYPSREVELQKFLDGQPGTAKITCKVSWIFPRLLVGNIQRSLPAMTITHTYYDCSKATLESDYWRPAEPQWLPATLMIPLTLQRNLFTKAYFYPIYPPNTLIIDLEIYNQEGRLLGKKDQCLALHSPQSGYQFLSFKDICKKLALDTEQNLAARLIARTEDGSRIPARIKLGLDLGVEGQQMPCNICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGN3</accession>
    <name>A0A0C1HGN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UPF0066 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rcsF</name>
        <name evidence="4" type="ORF">DB41_FX00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384379.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76494">
        <property type="protein sequence ID" value="KIC76494"/>
        <property type="gene ID" value="DB41_FX00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.783"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00104">
        <property type="entry name" value="tRNA_TsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="8"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="265" mass="30935" checksum="2F554940299374E2" modified="2015-04-01" version="1">MQSPSLSCSPIGYFYTSEKERYSLPKQAGLFKNNKGKIILNRHQNFEQALHDLAGFNKIWVIFWFHRNHHWKPKVLTPHGPPKRGLFATRSPHRPNPLGLSCLEITGVSQLEIDVINHDLLDGTPILDIKPYIEYVDAWTDTQQGWLESCKKKSSYPIIWEEEALAQVSYLNNLCSFNFQEEINFRLATHPYPSSNNRILHCKDNDYLLAYKAWRFFFKITLPSIHVIKISTGYDRETIKGEKKSVWNDVDIHREFLKKFNLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHI3</accession>
    <name>A0A0C1HHI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IU00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000152">
        <property type="protein sequence ID" value="KIC74068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74068">
        <property type="protein sequence ID" value="KIC74068"/>
        <property type="gene ID" value="DB41_IU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="276" mass="31909" checksum="F0F8FC867FA64AC6" modified="2015-04-01" version="1" fragment="single">MVNNMTPFSLIPSIRIPEEVQLKILSLLDEKELPIAGLVNKHWQRMAQDPSLWRPICQRRWKNLSHSSSPGKNWRKICKKQVQMSKTMRLTKGEYSKNKCKQTIYKLPNFSGKILALKREKQFAFIKATAGTAQIYHLGEKSCQLVYDNVKEESSRLIHYQEGHIIQVTQEGYLYRWKVNEALPQTSLCYLGNFENAYLAQNHLFLVNPHRTQFKIVDVRTGLSCYKTTSAAINFILCRNNQALIHCLDGSLYFINDIENSFSMNLIALEGILKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHV1</accession>
    <name>A0A0C1HHV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DV00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000037">
        <property type="protein sequence ID" value="KIC76904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76904">
        <property type="protein sequence ID" value="KIC76904"/>
        <property type="gene ID" value="DB41_DV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="389" mass="44098" checksum="023194F7DA3C3CC2" modified="2015-04-01" version="1">MIVFIQEKLLKDGRPTKHKAGTSPSGHAIANTLAISHLASTSSPPHQTSILGLLDHGQYSLQDKQSRETYDRKEPQELQVLLKRSVENIASTYEASRKLMKPSKSKQYSLLVSEVEEEVAKIKILGKVLTEKDQMVESKQIEDQEKILKQMYKDMPLGESVLLRWDIEMMKGMSRRPAEKIYTTSCGTFENPNASHLELSRWFSSYIYEGNYECFSCMYRLHDLAEGKDYNRMFTCIGLDKKEGQRKIERKLYNGKPSFWGNIQSSLFSIGRTLLSKDQSSGEAEEKKETQALSLPSTEASTAGFISLPTKPVSNYQIKQQKVLAKLAQDLPAMMEVWNVDSFQILTSEQMLAEGYEYEGAYSGDRILLFHKRVENQEAASSAMDPLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI21</accession>
    <name>A0A0C1HI21_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DP00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76964">
        <property type="protein sequence ID" value="KIC76964"/>
        <property type="gene ID" value="DB41_DP00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="161"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="369" mass="41422" checksum="737B0760719C2080" modified="2015-04-01" version="1">MSSGSNMISSLESTLDAYYDLYSKTQENKNDRSQRPILLLRTANGEKTLEVLSDRSQLPFLQKILAYLGKGEASLSKVANFLREKNQEIKTPTARKALQHLDEKIVNLNMRRWLCSIDPIFTTKTMGIQSWGCGASATYHSENGEEGVLDFVHIFPECATAYIADGTGHGNPTVRANKLEPIWDKFNRDFVSRFKSEMLGTHDKAQVLHFMKSILLDINTSFEIAGTASTFSMAIIVEINQKKYVCSAHVGDSSLWHETKGEIHRLTPESPLELSSLSKNSSIHLRIKEVQTGDKIYGFTDGVTDFLPAEVLHSILCHQPIDPLNLLEEIKTAIVHPTFQRDNYVNVKKLDPTNKNYSDDIAAFVMVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI75</accession>
    <name>A0A0C1HI75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DN00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76994">
        <property type="protein sequence ID" value="KIC76994"/>
        <property type="gene ID" value="DB41_DN00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="137" mass="16141" checksum="26296C736FCF91F3" modified="2015-04-01" version="1">MHYTTVQFLLLLFFLGFLSLTFLLGVYIIKQWGSPIPRLCHEFDKKIWMTLGLGIIFFGFYFIFITFLGWSLKGQSLRKVFIFLYNHTASCIYIGLSIFSFFSLSIYLARILIKHLYKKAAKKTLEKEKERASNKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIJ9</accession>
    <name>A0A0C1HIJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DC00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77089">
        <property type="protein sequence ID" value="KIC77089"/>
        <property type="gene ID" value="DB41_DC00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="60" mass="6810" checksum="47F596D65B78F7D1" modified="2015-04-01" version="1">MKSKLMSLVDKILLRKRGIIESVNNKLEKLLSNRTSSTSQPVEFFCQSNQRNSGLCLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIQ6</accession>
    <name>A0A0C1HIQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-lysine 2,3-aminomutase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">EF-P post-translational modification enzyme B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">epmB</name>
        <name evidence="14" type="ORF">DB41_CY00030</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysine = D-beta-lysine</text>
            <dbReference type="Rhea" id="RHEA:44148"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:84138"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. KamA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000015">
        <property type="protein sequence ID" value="KIC77134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383315.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77134">
        <property type="protein sequence ID" value="KIC77134"/>
        <property type="gene ID" value="DB41_CY00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.174"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022462">
        <property type="entry name" value="EpmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="PTHR30538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004911">
        <property type="entry name" value="DUF160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00314">
        <property type="entry name" value="L-lysine_2_3-aminomutase_(yjeK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00238">
        <property type="entry name" value="TIGR00238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="98"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR004911-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR603739-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC77134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="325" mass="37794" checksum="5651FCF7267BBF46" modified="2015-04-01" version="1">MQNSPALWRQIQRSNFTNWNQLVDFLELSPEQGEQILKNPSFKLNLPLRLAQKITKESLDDPILKQFLPVLDEKLEATGFQIDPVQDQLFRKETKLLQKYKGRALLVCTSACAMHCRYCFRQNFEYDSKKTSFANELELIRADLSLKEIILSGGDPLSLENRTLSNLLDQLDSISHLRRVRFHTRFPIGIPERIDQEFLDILRVRRVQIWFVVHVNHPRELDEEVLLKLKNVQCLGIPVLNQCVLLKGVNDDKETQKLLCEKLVDHGILPYYMHQLDRVKGTAHFEVEREQGCEFIRYLTANLSGYAVPKYVQEVPGESSKTSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIS1</accession>
    <name>A0A0C1HIS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cdsA</name>
        <name evidence="2" type="ORF">DB41_CW00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383282.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77159">
        <property type="protein sequence ID" value="KIC77159"/>
        <property type="gene ID" value="DB41_CW00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.150"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="284" mass="31596" checksum="EF3D24E0F449351A" modified="2015-04-01" version="1">MSNLQHRLLLGSMTTLFAILLLWLSPYLFFRPIFALILAAFVTLAAAELFHLAKSKNYQPLTKIGLTGCFLYTLSVYVSTQYGQAQILPYIVLILIVWMCFFYFFKTGDKPLLNISITLLALMYVAIPLASWLNIAYFFPEHSPQEGRWWLLYLLAVTKTTDIGAYFVGSILGKHKMAPYLSPKKSNEGAVGGLCCGLGASFTFYWISAHIPFQITLFQCLTLGILLSTLGQIGDLAESLLKRDADIKNSNQIPGLGGILDMLDSLVFTSPIVYIFLEIQSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIU7</accession>
    <name>A0A0C1HIU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CT00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77189">
        <property type="protein sequence ID" value="KIC77189"/>
        <property type="gene ID" value="DB41_CT00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4782" checksum="57CD079EC6682AB1" modified="2015-04-01" version="1">MSHHYAYLLIKALLLYSKKANPSLAGIKHPIELFLFAKQGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK92</accession>
    <name>A0A0C1HK92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nifS</name>
        <name evidence="3" type="ORF">DB41_IB00460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385822.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74913">
        <property type="protein sequence ID" value="KIC74913"/>
        <property type="gene ID" value="DB41_IB00460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1478"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="2">
        <location>
            <begin position="7"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="380" mass="40684" checksum="7E04FE970096629D" modified="2015-04-01" version="1">MKRVNRIYLDNNASTCVDPHVIHVMTEVLRTYPGNPSSPHSFGREARQVLSQARQTIASYLKVRPQEIVFTSGGTEGANMAIRGILGALTQGHIVTSNVEHACVHSVMDLLHHQGIEVTSLAAGLHGAVLPKAVAAAICPHTRLIALIGANNETGVKTDIKAIAKIAEEANIPFFVDGVALLGKEPLEIPAGVSAMSFSGHKIHAPKGCGFIYLKSSQKLLPLLHGGLQEYNRRGGTENLADIAGMAAAIQILAQTLPEASEKMLKLRIYFEESLKRHLGEAVHVNGEGDRVCNTVNLAFDGIDGETLLAALDMAGIAASHGSACASGAMEPSRILLNMGIPLKRVRESIRFSLSRYVTQEEIDRAINIIVNLVAKLKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKF0</accession>
    <name>A0A0C1HKF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74958">
        <property type="protein sequence ID" value="KIC74958"/>
        <property type="gene ID" value="DB41_IB00910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7170" checksum="D77326776054110C" modified="2015-04-01" version="1">MLLLVILIGATTHLDIRFSEFICLPLPSGSSAINIPIRVCRKWERADHKPYTPDHQFLGLVGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL24</accession>
    <name>A0A0C1HL24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HW00100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385480.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75098">
        <property type="protein sequence ID" value="KIC75098"/>
        <property type="gene ID" value="DB41_HW00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="330"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="534"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="688" mass="78967" checksum="0396A7918C2EF321" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL37</accession>
    <name>A0A0C1HL37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75113">
        <property type="protein sequence ID" value="KIC75113"/>
        <property type="gene ID" value="DB41_HW00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="416" mass="47968" checksum="6277F24A57262CA4" modified="2015-04-01" version="1">MNTVSFPSHYPIRSLSSRALPLSLIKPDSLKKGNITVSSSYLKIIGPSSTSLLSDFSYSSFLRRKISMSYSCTRSFTTRLPGRWQERLINYYKEDKKPENYYEDLTKILLKNLEDKERLDFFEKKGLPIFKNSQEDVEYVLELLKYFFPEPMQPQAGEKNRWANYKIVKFEALTGSSHTYSSPSAAYIADQLSKAILHMKYPMPPSIIEVGGMCHNDAFLFNLHLAKEGVNIHDYTGIDIHPGIQLANLFNRYVVQADHIKFMHEKADLALKKLFECSHERNKAIIAIRFLSAIEPQDMLAFFKSTSRLMKENDLFIFNYTTYDENIKRMAGSKSFSLAKEKVGDMFLTVVKRKEGHHVQTAFTSVQIDNLMSMHGLKRMDVIQVDKNIAGVRREFDPYARIVVASVKHYKELKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL41</accession>
    <name>A0A0C1HL41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">V-type ATP synthase alpha chain</fullName>
            <ecNumber evidence="7">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">V-ATPase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">atpA</name>
        <name evidence="11" type="ORF">DB41_HW00300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385506.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75118">
        <property type="protein sequence ID" value="KIC75118"/>
        <property type="gene ID" value="DB41_HW00300"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1386"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00309">
        <property type="entry name" value="ATP_synth_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="PTHR43607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="9">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_Xtn" evidence="10">
        <location>
            <begin position="100"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="8">
        <location>
            <begin position="229"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="249"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="594" mass="66534" checksum="1E17D28063691F7A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN00</accession>
    <name>A0A0C1HN00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreD</name>
        <name evidence="2" type="ORF">DB41_HH00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75723">
        <property type="protein sequence ID" value="KIC75723"/>
        <property type="gene ID" value="DB41_HH00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="167" mass="19239" checksum="238B1180A46008D9" modified="2015-04-01" version="1">MHLSRKNLFLTFFSGLLLTLGMPAIAPSIRLMFLVPFLIVSFYQKSFSRCLWYAFFCGFLLDLLSVQPPFGFYAGNYTLGAAVIYPQKRHFFADHLSTLPIMTFLFSFTITFFQVIFLYILGSPLSVGIRWIVSDLFVMPLGDALFAFLYFILLPLSLQKKSRHRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN07</accession>
    <name>A0A0C1HN07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="8">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">folD</name>
        <name evidence="11" type="ORF">DB41_HH00210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385223.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75728">
        <property type="protein sequence ID" value="KIC75728"/>
        <property type="gene ID" value="DB41_HH00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1219"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="1 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="9">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="10">
        <location>
            <begin position="118"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="161"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="296" mass="32048" checksum="8DAA8719E2B28185" modified="2015-04-01" version="1">MIINGKKIAQEIEEEIKATLLNMHGRPPCLAVIIVGDHPASQIYVQRKTQACKNVGILSLKIHLPSSLSEKELLDKIHALNLNSTVDGILVQLPLPPHINPSLVNLAILPEKDVDGFHPFNVGKMLMGETDGFFPCTPLGIRALLARSQIEVAGRHVLIAGRSNIVGKPMAAMLMQNNPEGNATVTIAHSKTKKIDSLTSQADIIILAMGQPLFLKADMIKEGVTVIDVGINKINDLSRPAGYRLVGDADFDHIKDKCAYITPVPGGVGPMTIAMLLSNTLKSYSKRLDLNLQKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ01</accession>
    <name>A0A0C1HQ01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GL00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384745.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76278">
        <property type="protein sequence ID" value="KIC76278"/>
        <property type="gene ID" value="DB41_GL00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="332" mass="36421" checksum="8CCA2936E0E5A6E5" modified="2015-04-01" version="1">MASILNVPREPYHLNFARKQLQSPIQRNYNPCQALKTALIKEIVKKSLLELAIALSFTGLACLFVATPLGMATLLLSTIASLAITTLLRLARAYCIFRVFQLKHSTSRKAVEKKTQFTSWVGFINALIPTTFRQLVDANTREVIVHEGGHALAAKILIKNPLVNVSITPFNGGQTTYYVRSLTMIGQYIGRANSELLIVAAGPALAVLAATTGYSASLALSKSHPELSRYLKTATLSTISQHFLYALSALWTTTSIQKHDFVNLMAAGLSPIVAAISIVALPILIRVGFYIYHRNKGSQKEKTNEKEKIALNNNVRFQGPLYNSLTLEAPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ21</accession>
    <name>A0A0C1HQ21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nudC</name>
        <name evidence="4" type="ORF">DB41_GK00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384672.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76298">
        <property type="protein sequence ID" value="KIC76298"/>
        <property type="gene ID" value="DB41_GK00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000210">
        <property type="term" value="F:NAD+ diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="149" mass="17011" checksum="E9A2F10FA15AD967" modified="2015-04-01" version="1">MKVSKSTNLYPLVTVGALIVADDGDILLVHSFKWKVDFTIPGGKVELGESREKAVTREVLEETGLFIEDLRFALVHDSIYSSEFINPNHFVMNDYVARLSPNSSKNHVILNAEADHYIWISPEKALGLSLNQELYSLIEWYIQHPYQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ46</accession>
    <name>A0A0C1HQ46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein lap1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">let-413_3</name>
        <name evidence="4" type="ORF">DB41_GJ00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000095">
        <property type="protein sequence ID" value="KIC76323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76323">
        <property type="protein sequence ID" value="KIC76323"/>
        <property type="gene ID" value="DB41_GJ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.905"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="630" mass="70586" checksum="4C06663F5A4CED86" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRL9</accession>
    <name>A0A0C1HRL9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">clpP1</name>
        <name evidence="5" type="synonym">clpP</name>
        <name evidence="8" type="ORF">DB41_EJ00030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042241773.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76773">
        <property type="protein sequence ID" value="KIC76773"/>
        <property type="gene ID" value="DB41_EJ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.518"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="203" mass="22603" checksum="F149B19610C0922B" modified="2015-04-01" version="1">MAKADKEKDNYSSIPFIRLEDRIDSVILESRRIFLSDAVDSNSAESIIRKLWYLELTAPGKPILFVINSPGGSVDSGFAIWDQIQLMKSPVTTLVCGLAASMGSVLSLSAAPKRRFATPQSRIMIHQPLIGGVIKGQATDLEIQAKEMLKTHEALIRLYMHQTGKDYETIQKAMDRDNWLSPQEALEFGLLDGIVHSIDDLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRS8</accession>
    <name>A0A0C1HRS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EH00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383789.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76828">
        <property type="protein sequence ID" value="KIC76828"/>
        <property type="gene ID" value="DB41_EH00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="2">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="179" mass="20651" checksum="415AF6D2CADB50D0" modified="2015-04-01" version="1">MAPKENLPKREWVVIICLILFMIVLTCLTHKHRFLSSRKYSEPHHLYNRHQTVRVEGAVEYPGLYNVEKTATLANVLEQAKVLLEADLSKISLNKKVNNSQLIKVPYKEYITVRVEGAVKKRGSLTVPRGTLMEDLIKLIEPLEKADVGRLKRKRKLRDGEIIKVLIKEKLLRDNCKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSE2</accession>
    <name>A0A0C1HSE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DN00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383508.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76998">
        <property type="protein sequence ID" value="KIC76998"/>
        <property type="gene ID" value="DB41_DN00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="932"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="993" mass="114930" checksum="BF9BB7F0983A68CF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSM9</accession>
    <name>A0A0C1HSM9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Diadenylate cyclase</fullName>
            <shortName evidence="10">DAC</shortName>
            <ecNumber evidence="10">2.7.7.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cyclic-di-AMP synthase</fullName>
            <shortName evidence="10">c-di-AMP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ybbP</name>
        <name evidence="10" type="synonym">dacA</name>
        <name evidence="12" type="ORF">DB41_DH00060</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably a homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate cyclase family. DacA/CdaA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383420.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77058">
        <property type="protein sequence ID" value="KIC77058"/>
        <property type="gene ID" value="DB41_DH00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.241"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019932">
        <property type="term" value="P:second-messenger-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01499">
        <property type="entry name" value="DacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014046">
        <property type="entry name" value="C-di-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034701">
        <property type="entry name" value="CdaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045585">
        <property type="entry name" value="CdaA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19293">
        <property type="entry name" value="CdaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004793">
        <property type="entry name" value="UCP004793"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00159">
        <property type="entry name" value="TIGR00159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="DAC" evidence="11">
        <location>
            <begin position="77"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC77058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="267" mass="29850" checksum="1C4130D73E4D95D4" modified="2015-04-01" version="1">MHILSWFIPAIEIAVIAVVVYYLLSFFWNTRTMDLLFGLLAVACIYALSIWLHLPVIEKLIHYFVSVAVVALLIIFQPELRLALSMLSVKGKKYREVTEFDKFLDSMAQSIYRLSEKRVGALLVLENQDSLDEYANKAVIMNANFSSELLESIFIKTTPLHDGAVIIRGTTILSAATILPLADDSSQLSKSMGTRHRAGLGTSQHTDALIIVISEETGKVAIARDGIMTRGVKIDRFKGIMRSIFTPPKTTIQSSFDAIGRLKTWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT94</accession>
    <name>A0A0C1HT94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CJ00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243726.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77293">
        <property type="protein sequence ID" value="KIC77293"/>
        <property type="gene ID" value="DB41_CJ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.3"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="485" mass="55032" checksum="81BD67C0F2720DBA" modified="2015-04-01" version="1">MNPSSSITIEHLPDEILVPILKECASPSLFSVCGRWYHLLANEVMPPLYKQIGKVHVPQGNVKEQALIVDKIYKLEEKLSGTAKVNAIFRQIFTLAKSFSPWEFKWKTEEKTGLTLANYSSYLLNINRLLLLERLPGGKEYLRREEIKHLPLGKKGELLRDWIEENCKDLTLLNLSGAGLIYLPPEICQLSKLGVLDLNQNQLTSLPAEIGQLSQLQYISLNQNQLISLPAEIGQLFQLQYISLNQNQLTSLPAEIERLSQLQMLDLRENQITALPAEIGQLSQLQWLYLNQNQLTALPTEIGRLSKLQTLDLNENQLTALPAEIGQLTQLQTLELNQNQLTALPTEIRQLSQLQTLYLNQNQLTALPTEIRQLSQLQTLYLNQNQLTALPTEIVQLSQLQTLKLNQNQLTALPKGVGQLSQLRVLDLSQNQLTSLPANIGRLSRLRWLYLNQNQLTRLPAEIRRLSQLITLELADNPLKNIAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JIW6</accession>
    <name>A0A0C1JIW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BN00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000234">
        <property type="protein sequence ID" value="KIC71325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71325">
        <property type="protein sequence ID" value="KIC71325"/>
        <property type="gene ID" value="DB41_BN00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2293"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="190" mass="21662" checksum="0058C2CEF5AB9799" modified="2015-04-01" version="1">MSREEIKYLPLEKKGELLRDWIAENCGNIVDLGLSRVGLTCLPAEICQLSRLQWLNLNQNQLTSLPTEIGQLPELRTLYLNQNQLTALPEEIGQLSRLLELYLDGNQLTSLPREIGQLSHLQELHLNNNQLTFLPAEIGQLSKLRVLDLNQNQLTSLPVEIGQLSQLLILELAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJI1</accession>
    <name>A0A0C1JJI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AX00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000219">
        <property type="protein sequence ID" value="KIC71505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71505">
        <property type="protein sequence ID" value="KIC71505"/>
        <property type="gene ID" value="DB41_AX00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="167" mass="19229" checksum="A3AD09EB0B9375CD" modified="2015-04-01" version="1">MPESLRRVYTIFNDLIKHPEVIRYVPQTIIIMFQLCTCHLSNVHQIALMHVGDQNLPLSTYRYIQSTNLDLSAQKQISPSNLYTATFCHMDTTERLTLLEFWSQHCEASGKKFSMLFQNKFAIMVTMLTQLTQASISRSSSRTGALFRISLTQLNVLFLKGKHRAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJR7</accession>
    <name>A0A0C1JJR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">clpX</name>
        <name evidence="9" type="ORF">DB41_AV00150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386903.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71575">
        <property type="protein sequence ID" value="KIC71575"/>
        <property type="gene ID" value="DB41_AV00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2251"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="8">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="120"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="418" mass="46231" checksum="4A8849E35DAE196A" modified="2015-04-01" version="1">MSKKPTPLKEVVACSFCGRSEEAVEKLISGPNVYICDKCVRLCAGIVDKKKTPNHELKLLKPKEIKERLDEYIIGQESAKRTISVAVYNHYKRLQALNKNKEDGENKIDFSKSNVLLFGPTGSGKTLIAKTLATILDVPFTIADATTLTEAGYVGEDVENIILRLLQAADYDVAKAEQGIIYVDEIDKINRTTANVSITRDVSGEGVQQALLKIVEGTIANVPPKGGRKHPNQEYIKVNTENILFIVGGAFVNLEKMVAKRLGRSTIGFTNESKESIDPNQKSMLLSKAEPEDFVQFGMIPEFIGRFNSIANCNELKLEDLKDILIKPKNAVAKQFAAMFELEGVKLTFTDEALHAIAHKAMEAGTGARALRMILESSMKELMYEVPSDSTIEEIIIDKETITDLKAPLIKRNTEKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK10</accession>
    <name>A0A0C1JK10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AU00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386847.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000217.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71620">
        <property type="protein sequence ID" value="KIC71620"/>
        <property type="gene ID" value="DB41_AU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="197" mass="23213" checksum="75B1BB34C96C7EE3" modified="2015-04-01" version="1">MGIKKILESVSSFAELKPLACKAKVHVSFWGTRYITVLGYEGTLPIDALAGKVLELVKKNPHFDETEREYGKAIVYPIDMLYRNSDKKAKIRNCFTRLLLFLRLLPIKIKPRRTDIPWRWRECDSPWETFDYTDGYYKVFYYYTQKQYEIAYREPLGWSEGPKELNGLDDDYWSGKGYKYSWPESLGIGLEKINDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKB3</accession>
    <name>A0A0C1JKB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rhs37</name>
        <name evidence="1" type="ORF">DB41_AN00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000211">
        <property type="protein sequence ID" value="KIC71730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386756.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000211.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71730">
        <property type="protein sequence ID" value="KIC71730"/>
        <property type="gene ID" value="DB41_AN00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2182"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1669" mass="191380" checksum="5F8E5482CB2D6B14" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL86</accession>
    <name>A0A0C1JL86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_BK00010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000231">
        <property type="protein sequence ID" value="KIC71351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386996.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000231.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71351">
        <property type="protein sequence ID" value="KIC71351"/>
        <property type="gene ID" value="DB41_BK00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024474">
        <property type="entry name" value="Znf_dom_IS66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13005">
        <property type="entry name" value="zf-IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="4">
        <location>
            <begin position="34"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="zf-IS66" evidence="3">
        <location>
            <begin position="107"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="2">
        <location>
            <begin position="191"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC71351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="476" mass="54464" checksum="E92A6A4E0F25DCF8" modified="2015-04-01" version="1">MQPSYEQLFKENAELRVENAQLRAENVQLKALVNRLEKVITKLEARIAQLEVQLNQNSKNSSKPPSTDQKANRSTTPKTEKRPYHPGASRQLLPASVVTSHEVRSVKACPHCHSAMHATDKVFSWQQIELPEIKPLVHQIDLVTSRCPCCHLETRPELKENEQFLLGPRLEGFINLLMGQYRQGHRAVRTMISALLPHVTLSQGFISKVKARTAALLVSSYETLVKAATTTQQPLHIDATSWRHAATNEHLLVLRVGNVIAYALRPYQNGATLKALVGQKIYCLVSDRGLAIHQIKVKIKQYCLAHLLRNIQGQAEQPNISLEDTQRLGHLYDTLQELFKDKHRLEKGQISQSTWQQYGYLNWRYIQEELQELQCWSSTKKLRKFCHKLLKQIKHFRAYLKDPAIPMTNNAAEESLRNLVIVRKLCLGSQSIYGKRWREVLHSCIETLYRQGKSILDFLTDAIHAARTKQPIPSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLV4</accession>
    <name>A0A0C1JLV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KQ00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72255">
        <property type="protein sequence ID" value="KIC72255"/>
        <property type="gene ID" value="DB41_KQ00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010330">
        <property type="entry name" value="CoiA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06054">
        <property type="entry name" value="CoiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="290" mass="34255" checksum="862121AC2ECF4765" modified="2015-04-01" version="1">MHFYALDEKENLVSAHQADKRLHYYCRECLGLVKSQGGLLRQMHFYHLEPNRSCRQNGKSLVHLQVQHYLQNCLPDCELEKEFPLIKRIADVYWEKEGLIIEIQCLSISAHEIEERNQDYARIGYQVLWILHDRLFNRHRLTAAEYFLQDSLHYFTNIDSEGVGYIYDQWDRIEKGKRVLTLGFRKVNFFSYHSHLKESLALGSYPPWIKKRLESWRGYFTGDYLDYFLTMQESEKAALLSALSVDEQSGLMHVGENLQPGVKRALKKIIRLISFSYRLGLNFILEKLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM99</accession>
    <name>A0A0C1JM99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative type III secretion chaperone SycE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sycE</name>
        <name evidence="1" type="ORF">DB41_AS00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386817.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71666">
        <property type="protein sequence ID" value="KIC71666"/>
        <property type="gene ID" value="DB41_AS00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010261">
        <property type="entry name" value="Tir_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05932">
        <property type="entry name" value="CesT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="130" mass="14840" checksum="D7C8E01264855899" modified="2015-04-01" version="1">MVDLKQFCSQLSKDLGLNEDLLQEEAPGIFSLPIEEEVSIKLGTLAEGFSLQCILCECPKENPEAFLAEIMDANLFGQTTRNCVLGLTEDGNRLTLSRIIDYNLDYKSFNEFLQDFYNVALFWREQALHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMH7</accession>
    <name>A0A0C1JMH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386383.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72480">
        <property type="protein sequence ID" value="KIC72480"/>
        <property type="gene ID" value="DB41_KK00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="10001" checksum="C40B5D0B49FC1C36" modified="2015-04-01" version="1">MTIHSTSTAMPLYRHPTGRLFRSHPQGGYEEQTPDGWIPVTNSHLIRSIQEDSFSISPTPPALACRSLTIYSQPTTIPSHLFLNLLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPB9</accession>
    <name>A0A0C1JPB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KN00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000193">
        <property type="protein sequence ID" value="KIC72381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72381">
        <property type="protein sequence ID" value="KIC72381"/>
        <property type="gene ID" value="DB41_KN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7654" checksum="6F63F49B38262E9F" modified="2015-04-01" version="1" fragment="single">PWVVMTFLAFLFFKGNIKKLKKQVKPIRILINEKQLTNDPSALLFQIDSRKGRRPSRHLGAATGFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPM8</accession>
    <name>A0A0C1JPM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M15_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KK00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386389.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72486">
        <property type="protein sequence ID" value="KIC72486"/>
        <property type="gene ID" value="DB41_KK00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1947"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013230">
        <property type="entry name" value="Peptidase_M15A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08291">
        <property type="entry name" value="Peptidase_M15_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M15_3" evidence="1">
        <location>
            <begin position="120"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="277" mass="33026" checksum="7582835F4784B0B4" modified="2015-04-01" version="1">MKYFSVVLTFLLAFFLSGCFFSEEAESERARLQNAIGEYIYRRHNEYLFKPEPATQSAPILYSWENNSFHSITKEYFRCKGSSLNPPHVVQRKQETLRFFDCGGAERHSLPLHNDKEFVYPILINLLNYLQHKSGKKIVITSGHRCPQHNIYVDDSIENQSSKHMIGAEVSFYVQGWEDKPAEIIKLIHHYYSETPKYKGLKDFQEFSRYEKQDTNVSTLPWMNKEVFVKLFKKKEGRNFDNRHPYPYISIQVRYDMETQTKVFYSWEKAHRNFLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPX4</accession>
    <name>A0A0C1JPX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JM00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244028.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73260">
        <property type="protein sequence ID" value="KIC73260"/>
        <property type="gene ID" value="DB41_JM00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="468" mass="53476" checksum="E9470D4C627591D0" modified="2015-04-01" version="1">MEKKWLFGVNLAMTFTVIALLISALAYRWTRPLEIPVNTLTDIKRNLPRSCYSQTQEAYDAIRHSILQLKHFPITLQLPDLRKHLIYYGTNDRPDAKEALPLLHFAFNGNPSVSSISPAEKMYISYNRQANPSQYVFNPDNLPTPLWLQATANDQDASIKVNMIDDKGQIIQEPCSYAEFTLPKKEYVRTHVPWEIGKWRVDGSLLARQKARWYGTDRFLEDHGGSEHSLNMGKQRLDFGEGEGVYSLFVGLGDTLIWKEEQWKLVKPGMDSLGYPLLIIKKIDDRLMQLELWDIEGRSKIALNLLKSSEPWMPQNALQNFKFLGSHTHSQFVFEISKKRILLKPKDWLILTSSGWKKLSKPQEVDDYVSRKLVGILFIFGGIERKNEQQLLVGTLYNSSRSEAKPLELPITSAFLGRRKAEGKEKDLPSNNSLPPTSSPADLNAPPPLPIISKRFETEKTLEPLNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQA7</accession>
    <name>A0A0C1JQA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KD00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386285.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72701">
        <property type="protein sequence ID" value="KIC72701"/>
        <property type="gene ID" value="DB41_KD00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011579">
        <property type="entry name" value="ATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004256">
        <property type="entry name" value="DUF234_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01637">
        <property type="entry name" value="ATPase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03008">
        <property type="entry name" value="DUF234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="DUF234" evidence="2">
        <location>
            <begin position="313"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="466" mass="53281" checksum="211A36BF5779167D" modified="2015-04-01" version="1">MKFINRQQELSRLDRLANSEEAAMAVIWGRRRVGKTRLLLEWAHKYQGIYYTADESAPAIQRKYFALALQQALPDFAAVEYSDWHSLFMRLAKEAMYTGWRGPLIIDELPYLISSSPELASVLQKFIDHEGKKAKMIVALSGSSQRMMQGAVLDASAPLFGRANEIIKLGPITAGYMAEGLNIKSSREVVETYSIWGGIPRYWELVNNNRGSFFENIDQLVLDPLGALNDEPNHLLLEEAAISLRPILDAIGLGAHRLSEIAARIGQPVTSFMRQIQRLLELDLIEREISFGSTEYNSKRTLYKIKDPFMRFWFEIVAPQRSYFTQISSAQRQAYLKNSFQHIFSVTWEDLSRAAVPRFPYQLSNIAFGRASRYWHKQDSEWDILANSVEGKALFIGEAKWIAKPPSAQWIYKTIEELKYKGLPPTARQSNKQVVYGLFIPEKPKDLDLPENIQVIDANEVLQVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQB1</accession>
    <name>A0A0C1JQB1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">khpA</name>
        <name evidence="2" type="ORF">DB41_KD00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A probable RNA-binding protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386287.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72706">
        <property type="protein sequence ID" value="KIC72706"/>
        <property type="gene ID" value="DB41_KD00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1863"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="9343" checksum="C21459602205AF17" modified="2015-04-01" version="1">MKEFVAYIVKNLVDHPDKVKINEIGGTQTLIIELSVEKSDIGKIIGKKGKTINAIRTLLMSVASRNGIRVNLEILEDGNPVKQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JST7</accession>
    <name>A0A0C1JST7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JH00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73551">
        <property type="protein sequence ID" value="KIC73551"/>
        <property type="gene ID" value="DB41_JH00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4539" checksum="88824441E8E8FAD7" modified="2015-04-01" version="1">MSPLNVGFYLEAKHFNRMQSYPSKKPSHSHSKYLIKCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSV3</accession>
    <name>A0A0C1JSV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux pump, RND family, outer membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_JG00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73561">
        <property type="protein sequence ID" value="KIC73561"/>
        <property type="gene ID" value="DB41_JG00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="496" mass="57007" checksum="051620BDE7B23191" modified="2015-04-01" version="1" fragment="single">MFLYQILEMTPTMNKFFYLSLALIAMSGIYTSCQRIGPAYKNPQIRLPDQWEIGQDQTLLKQVPSVVQEEDELPNWWAAFHDAVLERLINRALENNPEVHIAYQRLQEYQALLLESRANYFPMVHMGMGHTNAVSPADGILFQQPSLINYLKTQNVKNQRRYDFFHLGPMVSWEIDLFGRIRSENLARKAELGASHENLMAIQLSITAEISKAYLRLRSIQHQLLAEETYQQILQARANLLKERLVLNHSTLDSIAQVEIKICESKNAILQFKKYFEQYKHRLLTLMGETLWPLEENLLCYAPMPQPKVPLALGVPSDLLHQRPDIRQADRELAAATYRIGRVMAEALPHFALIGSIGGMSKQLADILSFKNLYWLYEPLTSFPLFDAGKNKASVNVYKARAKVAFSHYHQKLLNAVEEVQLALHSLQSEEKRLAENKNIYSYAASSLKRAHLLYQQGIGDLVAFNLAEDEAHRRKMQWLVAEEEYALSYVTLCKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUY7</accession>
    <name>A0A0C1JUY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385691.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74880">
        <property type="protein sequence ID" value="KIC74880"/>
        <property type="gene ID" value="DB41_IB00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1445"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="91"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="160"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="195"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="458" mass="49832" checksum="DC1942CA2F7EB729" modified="2015-04-01" version="1">MGDLSLVNYLIEQGANVNTVDQSNQSPLYHACNEAQIHFDIIHSLISAGANLHQTTDDNQTCLHTASEKGNVEVVNLLIQQGIDVHVLDKTGRAALHYACCVNGNQSLKIIEYLVNAGADPNQKDNANKTPLMFAYKHSNFAAVHYLIPITKDLDTYDEEGYSILHKACILRQESIVRLLLEYGADVNLVALNEGGSTPLMEACFLHKTERNANIVDLLIDAGADINIANEVNSDTALIFACRGRGNVDMKIVHRLVEAGANLNHVNREGVTALGVAKSCKVSACVAYLSSNPQPVHTSHNRPAFVRKAYNEATKECATQVASRSVRMLITTGKNISSQERKEIFTIIIDQLGSSDFFASLVGDDYEKTNSRNKLAEEIKKELDLLFSSGFELSEVKQSIKYAIAQWKALQAPRPSAYLPQEGSTTTTQATDSHGNLSDTASIISGAAQIAGTVFSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVW4</accession>
    <name>A0A0C1JVW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385916.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74531">
        <property type="protein sequence ID" value="KIC74531"/>
        <property type="gene ID" value="DB41_IJ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="316" mass="35875" checksum="A01F7D3ED0A477F8" modified="2015-04-01" version="1">MLALDTLWLNYLQKSHRLALWVFSIGITLDIYYTLLKRLITYLNPLDQVLLFTQIAKESIQNDKKSELCEAVEALTETALISTHHMNPTLCNQALQAMPNIIRNFLSSSKRIAQIATDARDKNSDIHDHTSYILYYIYERISLINEKALAKKLEQVAATLVAVWGKIVLHCAKFDLTLVNYPLRLLSCHAKAAINQGLPDIGVKASLTLLEISRTILEEIDYTSLNLKDPFFSLINGLEEITQSTFLQDKSINLKILMQPFQDLKGLFNDPKVAAHRDTSLIIKNIDRVLGEYEALELVMKTIPPLPDIPEEKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW89</accession>
    <name>A0A0C1JW89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AX00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000219">
        <property type="protein sequence ID" value="KIC71502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71502">
        <property type="protein sequence ID" value="KIC71502"/>
        <property type="gene ID" value="DB41_AX00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="28126" checksum="9A464E83E8C5B7F1" modified="2015-04-01" version="1">MSFQGLQHWDLSHQLSSTAHHHNQQPQLPFPACLQHHNHLLLHQGCLLLCQTSASSHQWILHHPLHPCQLPLLLHLEAHCRQKTSPAPFPTPTCYLSHIPLPPITREDSQAIPASLNILSESKVLLHSSFYHYLTTSINLPPLTKEHIHTIYTHPTYSMMLPTALTQSYWYLLPFAHKPLSHKYPAKDYATLAMHFLAQSVDDAALKQIMTFYNKLQHPLLTPYVYPTPTSTSHLTPQKVHVSYNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWQ0</accession>
    <name>A0A0C1JWQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AS00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71657">
        <property type="protein sequence ID" value="KIC71657"/>
        <property type="gene ID" value="DB41_AS00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5250" checksum="1C7E2DEFAE6CB8B6" modified="2015-04-01" version="1">MRILTRAKKINCLGQLLLTRIKPFSSKSLLVEKLVKVDAPILDKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWR0</accession>
    <name>A0A0C1JWR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AR00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000214">
        <property type="protein sequence ID" value="KIC71672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71672">
        <property type="protein sequence ID" value="KIC71672"/>
        <property type="gene ID" value="DB41_AR00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2200"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="148" mass="16941" checksum="5243B28D48986888" modified="2015-04-01" version="1">MSREEIKHLPLEKKGELFRDWIGENCDKIPALNLSLDLSRIGLTYLPPEIFQLSQLQALDLSQNQLTALPIEIGQLSQLQWLNLSQNQLTSLPAEIGQLSQLAWLYLSQNQLVSLPAEIEQLSQLQTLELTENPLKNIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWR6</accession>
    <name>A0A0C1JWR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385693.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74881">
        <property type="protein sequence ID" value="KIC74881"/>
        <property type="gene ID" value="DB41_IB00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="19260" checksum="1F8938F9540BCA4E" modified="2015-04-01" version="1">MEPIVNHFLNNFFYEKDQLEACKNRMSFVEKRQDRRPYENPLLVEFGPKHLCQTGIEEKNRISKIQIFAERKIFLIKSEGEQVELSSYFSNIPSLMATNGAKSYVENHFFKLHQLSSGDYKLESYARGLGGGKARAIHKAVKKGNVKQLKKIIEIEIKKRIVIPLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWS8</accession>
    <name>A0A0C1JWS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74896">
        <property type="protein sequence ID" value="KIC74896"/>
        <property type="gene ID" value="DB41_IB00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5200" checksum="AAD6080DDAD44478" modified="2015-04-01" version="1">MLYFWGAAYYSVMIGMQTSLGLIRAPSKQTSPFDYPKTVNEAYNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX15</accession>
    <name>A0A0C1JX15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0051 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufD</name>
        <name evidence="3" type="ORF">DB41_AI00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386717.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71797">
        <property type="protein sequence ID" value="KIC71797"/>
        <property type="gene ID" value="DB41_AI00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2159"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="28"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="448" mass="51115" checksum="52A61118FD29388C" modified="2015-04-01" version="1">MITENYTDQQAFQQMLQKMYTEAIEEKDPTRKLKEKAWLRFLEIGLPTRQSEVFQYLRLRNLYIQAFEPAHVIPLSADSIAPHILPECSGSVLVMINGNYYPELSNLSALPKRMVILPLKEAWRTYGSFLNNQWNKLLIEEKDPFAILNAALHRQGIFIYAPPKTLAEVPLQLLHFNSHEPNLSLWTNPRIQGFMGAHSQLDLIATHVDGPGKQFLSNISIELAMDEESHLRYFQVPFEILNKHWYFEAFRASLKKGSTFKSILASKGSTSLRNDYRIVLAGENAEASLNGLWMLSDQAEAHANILVEHQAPYCRSMQLFKSVLNDASHSSFEGKILVHQAAQKTQAFQLNSNLLLSDKAKADSKPNLEIFADDVKASHGATMGQLDQEQLFYLRTRGYSEKAAKNLLVYGFCKEIIEMIPYPSLMNAINKQAYRYLMQEPGDETSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX38</accession>
    <name>A0A0C1JX38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AF00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386686.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000206.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71822">
        <property type="protein sequence ID" value="KIC71822"/>
        <property type="gene ID" value="DB41_AF00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="287" mass="33390" checksum="F6D237578A1503D1" modified="2015-04-01" version="1">MHTKTQILIRILLNRFHPKTSQEFLKGLPENEAKQIIEHQIITADVDPIFVKPHEFLKEIHYSWVAPYVQKFPTHLQNLMVSALPNPLAASLKKYLNISDPSVSMPKPVRAFFIRKLYDQVKQTEILSPAFLPKQDLSILLALSRREIIYLIDFLGLYDLAEELRHVVDKKSLQKVYACLDSKKIQFVRLCLHQKSRFIAAKMDLQKWKGESTELQRKIHQRGLYRLGKALSGTHSHFMWYLLRKLDIGRSAIIEKHYKLPSSPAVTSVLIQQVINVMNFLKPKSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXG6</accession>
    <name>A0A0C1JXG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HW00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385471.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75091">
        <property type="protein sequence ID" value="KIC75091"/>
        <property type="gene ID" value="DB41_HW00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="342" mass="38391" checksum="CFF3121224886A96" modified="2015-04-01" version="1">MREDAIKENYSSYAPRGPLSEDYPLDFKASDAIQATERYSSSVASCKDFPLPIYAAKDFFIESEQEANPKIAEMQKAKQKEAILKRNKKSFWQLFNKETLVSWKDKAFNFFGKNKLANIKNASITAPLTIEPTSELAPAKINKKEDIEAQRIKEIEDTLVAYELELQNANGGNMKAMMEMMCKISILLGSLGHRYNKKEIDDLFKHLEVNVKKRVKTFEGGRAWTYVSVFLQGTGAALSFAPLGGQMLGDTSLFGKVLTNLGQTSQGISGFGHATSKIGDIESEKKMAARTEHDHEGEKLKQTRHDRDRSIEKIHQSSQQLFAIMNELARTHTESVKRAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXI5</accession>
    <name>A0A0C1JXI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplS</name>
        <name evidence="7" type="ORF">DB41_HE00060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385073.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75790">
        <property type="protein sequence ID" value="KIC75790"/>
        <property type="gene ID" value="DB41_HE00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1140"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC75790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="15527" checksum="971E38AC086E4758" modified="2015-04-01" version="1">MRKHALVEMIQNEQLKKDIPNFRIGDTIRVHTRIIEGQKERIQVFTGTVIARKGSGLSETFSLHRVAYGEGMERLFPLHSPRIAKIEVIKEGQVRRAKLYYLRGTSGKASKVKGRVGFNRKSAAVEKEPVAANVANES</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXQ2</accession>
    <name>A0A0C1JXQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75855">
        <property type="protein sequence ID" value="KIC75855"/>
        <property type="gene ID" value="DB41_GZ00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5885" checksum="6B8FFA623F4074D3" modified="2015-04-01" version="1">MNFKHRVSIKLDKNLTLKLSRKMRPFKLLASFLRIIDLKKLDFKVKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY02</accession>
    <name>A0A0C1JY02_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GW00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384915.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75930">
        <property type="protein sequence ID" value="KIC75930"/>
        <property type="gene ID" value="DB41_GW00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1044"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="273" mass="30810" checksum="1FE30FD179107226" modified="2015-04-01" version="1">MKICIIGCGYVGRSAAIKWKNEGHEITVTTRCLKKASELRQWIDHVYILGEDWQKLLEKQDVVILAVAPDSPADYRPTYLGTAEKLVKALENTHVSQVIYTGSSSVYGEQGGLWVDEETKPHPTQTNSKILLSTEEILFQAATSYRQICVFRLGEIYGPGRSIVERVKRMLSTGCAGSGDNFTNLIYLDEIVSAMAYAQQNKLAGIYNLCDDFHILRKELYKKISKFYGWPDVQWNPSLQSSFQGNKKVSNEKIKTAGWQINKENSGLRSILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY58</accession>
    <name>A0A0C1JY58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_KU00080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386539.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72112">
        <property type="protein sequence ID" value="KIC72112"/>
        <property type="gene ID" value="DB41_KU00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="5">
        <location>
            <begin position="206"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="374" mass="42710" checksum="FF53D2AA48C7F777" modified="2015-04-01" version="1">MNTYKDIHCPHFAICSGCTINKDVDNPPLLKEVQNFFSEQNVPFNYYSEQAVKWRYRAKLAVRGSAENPLIGLYENGTHQVVDIPLCRVHHPSINQAVEKLKTWIKAYKIKPYNEITQEGLLRYVQCVVNRSSGRVQLSLVLNASGGREELLAAKLLWELDPHGWHSIWINWNQQRTNVIFGKEWVLVKGEEDLWETLAGAKVCFHPANFAQANLAVFERLLNDLKSSLIAKEKIVEYYAGVGVIGFSLAKKAEKIECCEINPWARISFEKARQHQGFSHISLVSGSSSSHTELLNHANVVIIDPPRKGLDRSLLSALLENEFPQELHYISCGWNSFKQDWKELTKSWQLICAQAYLFFPGTNQLEVVAKFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ49</accession>
    <name>A0A0C1JZ49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243884.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76290">
        <property type="protein sequence ID" value="KIC76290"/>
        <property type="gene ID" value="DB41_GK00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.912"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="190" mass="22102" checksum="075D15E6B7ED2344" modified="2015-04-01" version="1">MLFTSWKIAYEYLKPETGLVYVHLNKSHDLKKSLTIYDKLGFAHQLNMDEMEFLLQKRATMLCSTINNFVTNNQVGEAKKLIDNLLKMILSEYQRGYADNDHALMQNTGAIGTLPFHIDVGQFVVNLNISDPTVYKQELFSKTFKFRLWLAKHHPELKTYLDKHLLEIIGPEMHQLIPRLKNPHAWSVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ77</accession>
    <name>A0A0C1JZ77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_GJ00040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000095">
        <property type="protein sequence ID" value="KIC76325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243881.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000095.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76325">
        <property type="protein sequence ID" value="KIC76325"/>
        <property type="gene ID" value="DB41_GJ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.907"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="475" mass="53619" checksum="322DF260EBB42301" modified="2015-04-01" version="1">MQLSPAYEKAKAYLEFCLKLSSEVSSSSQPVTPHFSSKGKDKEKSLPSTDSPKERYTELLFDLLEEPSIQENLILKKILENQVEELMNHENEELTEKEKVSYKWTKKLLGENKKVRQFVIEKLKQIYQGSPSLPTVAPQNPISTSSLFSSTSQPATTDSSLFSTTKGIQPLSPPSTTPISMASLYKAILQVHFPNGNRDLIKQAGILDKIYKIKPDIPIEEKVPYIFQKLFTLAASLSHIEFEGNTKESKAITLFNYSSYLLNINRLLIWQKLPGGTKYLNQVHIKALPLKKKGELLTQWIEEHDKNITYLDLEALGLTFLPPEIAQLSHLQTLRLDYNQLTSIPAAIAQLSHLHTLRLDYNQLTAIPAEIRQLSQLQNLYLSNNQLSAIPAEIRQLPQLQYLLLNNNQLTALPAAIGQLSQLQYLDLSNNQLTALPVEIGQLANLQWLYLSNNKLTSLPPLSQLRTLEIDGNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZF0</accession>
    <name>A0A0C1JZF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GG00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76395">
        <property type="protein sequence ID" value="KIC76395"/>
        <property type="gene ID" value="DB41_GG00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5196" checksum="EB9B48256374E72C" modified="2015-04-01" version="1">MSKWIRALIHMCQAIKLSIDQMKNEGNLGKSHFKDHLGGVFKAILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZL5</accession>
    <name>A0A0C1JZL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative carboxymethylenebutenolidase</fullName>
            <ecNumber evidence="2">3.1.1.45</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.45" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76440">
        <property type="protein sequence ID" value="KIC76440"/>
        <property type="gene ID" value="DB41_GC00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.834"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008806">
        <property type="term" value="F:carboxymethylenebutenolidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="13"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="238" mass="26564" checksum="3492F3183E5B5C44" modified="2015-04-01" version="1">MNVSYQADGLCCEGYLVNPKEMRHAQPAVLIAHAWYGQDEFARKKAHELADLGYIALAIDMFGHRKNATCDEEASSLIKPLYLDRKLLQVRISAAFETLLKQPGVDGTRVGAIGFCFGGLAVIELLRSGAPIKSVVSFHAVINYSGVNSFPIAKNIKGSILLLHGYEDPLCPSKEIQYLQRELNDARVDWQMDIYGMTSHAFTNPLVNDKKKGLIYNEKASTRAWLAMKNFFHETLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0L6</accession>
    <name>A0A0C1K0L6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243885.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76291">
        <property type="protein sequence ID" value="KIC76291"/>
        <property type="gene ID" value="DB41_GK00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.913"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="135" mass="15829" checksum="4F238E05FD99E172" modified="2015-04-01" version="1">MKKYLKFFILFSLFIICAYSAGRLYYALTGGFTIDNISSSLSYNEKWAMPTLSSSEKEDLHQILSQKFRYLGKGCQSYVFASEDGLYVLKFIKYQRFRPQAWLDYFASIPFVNRYRLAKIEKNIISLICYLQAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0U3</accession>
    <name>A0A0C1K0U3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-RING_7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EJ00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383851.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76775">
        <property type="protein sequence ID" value="KIC76775"/>
        <property type="gene ID" value="DB41_EJ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.520"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003743">
        <property type="entry name" value="Zf-RING_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02591">
        <property type="entry name" value="zf-RING_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-RING_7" evidence="2">
        <location>
            <begin position="199"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="257" mass="30088" checksum="96913B10EBF5C101" modified="2015-04-01" version="1">MQEALNIILEIQEFDMQLIQLMRLKKERQDELHNINSVKSDLQHQSLVKESEIAELKKHIRLVEGEHHDIVAKLKKLEAQQNHVKKVEEFNALSQEMSAVDRERIAKELRLSDLYDKLAIEEDHLKNLTQSLESTSESSKALEAEIMESIREINAEGRQLKQKRDELVLKADPETFRIYERLLRNKKDRVVVPIENRCCSGCHIMLTAQDENLVRKGERLVFCEHCARIHYWQESEALEGTSVATKTRRRRSTKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1U5</accession>
    <name>A0A0C1K1U5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">mraY</name>
        <name evidence="8" type="ORF">DB41_FD00100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384080.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000066.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76651">
        <property type="protein sequence ID" value="KIC76651"/>
        <property type="gene ID" value="DB41_FD00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.651"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="416" mass="46102" checksum="26F3751EE7E3787A" modified="2015-04-01" version="1">MIIFLVDWLKYTLNIKVPMVFTYYSTRMILAAITSLIISIFLGPYFIKKLYELKIGQTIRVEDCPLLGQLHEKKKDTPTMGGVLILFSMLISMLLWMDITHVFTLILFITTVWLGVVGGYDDYLKLKHKNPKGLSGKKKLFYQFTLSAFIALYLLCPSVSSSIQMKNWFAPPIVKEQTATKTKWGPLVMKQEATHSSGPTAISLKDYATRIYLPFIKNHWLVLKGALTLVAALFIMFVITGSSNAANLTDGLDGLAAGCLIIVAGCLALIAFVSNHIQIAGYLNILYIEGSGEIAIYLSALIGACLGFLWYNSHPAQVFMGDTGSLALGGIIGVSAVLLKRELLLGLVGGIFVAEALSVILQVLSYKYRNKKRIFLCAPLHHHFEYMGWAETKVVTRFWIIGLLLGILGIASLKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K247</accession>
    <name>A0A0C1K247_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_ET00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76741">
        <property type="protein sequence ID" value="KIC76741"/>
        <property type="gene ID" value="DB41_ET00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5674" checksum="C507BE4643B6CCA4" modified="2015-04-01" version="1">MIRNQGDTSIAWDIKQFLGFSFSHPLLAYKVFLYKHFYIKMLHRPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2I0</accession>
    <name>A0A0C1K2I0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein YciH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yciH</name>
        <name evidence="6" type="ORF">DB41_JG00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244020.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73567">
        <property type="protein sequence ID" value="KIC73567"/>
        <property type="gene ID" value="DB41_JG00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="5">
        <location>
            <begin position="29"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC73567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="10124" checksum="77E7A4C423A15BFA" modified="2015-04-01" version="1">MPFTIEGQWVPSKPTSSKPPKGVKIRLVKRGKNIITTILNLNMLSNELVHLASHLKKKLGCGGAVKDTDIEIQGDNVSKVRKILEEYGIKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K336</accession>
    <name>A0A0C1K336_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MscS family inner membrane protein YnaI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ynaI</name>
        <name evidence="8" type="ORF">DB41_DB00130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77106">
        <property type="protein sequence ID" value="KIC77106"/>
        <property type="gene ID" value="DB41_DB00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC77106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="368" mass="42586" checksum="0EAAEF0BCBD625A8" modified="2015-04-01" version="1">MRETMLLEFMNMFHSILSFTMDGTYKWILEAIGIVLLVLIINFFAKRGLEKLHLYFERTNQIWKDSFVQSFYRPLSAYIWFYAFFQLIDLISHRVFEGTIFSNLPKVLSIGLVSAIAWFLMRWKKAIIFNMHLQSLKHDQPIDSGKIDVINKMWTIIILFLTALSVLEITGQNINTLIAFGGVGGLAIAFASQEMIANFFGGLMVYVTQPFTVGDWINLPERKVEGNVEEIGWYMTRVRTFEKRPIYIPNSMFSKVVVMNPARMSHRKFDETIGIRYSDMPVARHIISDITTMLIDHFHVDRRLGPTVNLEGFGSYAVNIHISAYLLDIDHRSYIQAKQEILFSIYNILNKHGAEIALPTSLQLYKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K355</accession>
    <name>A0A0C1K355_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CX00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77146">
        <property type="protein sequence ID" value="KIC77146"/>
        <property type="gene ID" value="DB41_CX00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5636" checksum="0D766DDEB611AA42" modified="2015-04-01" version="1">MNEYNNERTHTGKYCFGKTPLQIFLDAKHLAQEKMLDKLQLTEIVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K384</accession>
    <name>A0A0C1K384_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CS00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77206">
        <property type="protein sequence ID" value="KIC77206"/>
        <property type="gene ID" value="DB41_CS00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="6147" checksum="60C5E03B751F692A" modified="2015-04-01" version="1">MKETHKVASSLLSYFNENSSSLQDEKVEKDKNWLVFRFSLRTKKRIRLTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3A5</accession>
    <name>A0A0C1K3A5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77246">
        <property type="protein sequence ID" value="KIC77246"/>
        <property type="gene ID" value="DB41_CO00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="261" mass="30031" checksum="76FAAEB3AE5503B3" modified="2015-04-01" version="1">MKNLFFLGWSKALKNINKSCKSLDFKINKTFFIKKKIYRKKTSTVRLAILLFFLGWASLLNLQGTEQIAVKKGTLIVDYKTDLEGDRLDRIRFWLKDGNHSQKMYPKGHAFVEDRKNRSRIVVLEDVTPGEYTLEFLIPNKDAFFEESSLRHIHLQAGEVVKVDKTFKRRQVNYYSAKQLHEWKIWWSFLSNLSLKSITPMYPAYNPSQEVGGRGSLLDANATLNRRNSFYAKKARALLNPSSISLPVLPGKAKSAAGLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K4J2</accession>
    <name>A0A0C1K4J2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IR00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386052.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74242">
        <property type="protein sequence ID" value="KIC74242"/>
        <property type="gene ID" value="DB41_IR00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="143" mass="15548" checksum="886AD3B79F807A4D" modified="2015-04-01" version="1">MIHPSVRTTSRVPPSIKIEEQENPTVRAIQICKEKYLTDFKQKKIIALAIVIGTLSLTLLSVVGSIVAGLTLASPLAVALLVATPLAIVGIGFLIKKIDDKTLYWSGGVANLLIEKKAKEEKEAREKEKNNACKVTVSENNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K4Q9</accession>
    <name>A0A0C1K4Q9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Potassium-transporting ATPase potassium-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP phosphohydrolase [potassium-transporting] A chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-binding and translocating subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-translocating ATPase A chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">kdpA</name>
        <name evidence="10" type="ORF">DB41_IQ00050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KdpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386038.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000148.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74302">
        <property type="protein sequence ID" value="KIC74302"/>
        <property type="gene ID" value="DB41_IQ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1656"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00275">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004623">
        <property type="entry name" value="KdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30607">
        <property type="entry name" value="PTHR30607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03814">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001294">
        <property type="entry name" value="K_ATPaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00680">
        <property type="entry name" value="kdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="563" mass="60664" checksum="29168B31542CB18C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6F1</accession>
    <name>A0A0C1K6F1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IE00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000139">
        <property type="protein sequence ID" value="KIC74837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385875.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000139.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74837">
        <property type="protein sequence ID" value="KIC74837"/>
        <property type="gene ID" value="DB41_IE00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1055" mass="121852" checksum="CE1EA10ED704AC3E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6X3</accession>
    <name>A0A0C1K6X3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_HY00080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243957.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74982">
        <property type="protein sequence ID" value="KIC74982"/>
        <property type="gene ID" value="DB41_HY00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="97" mass="11065" checksum="ED184D32BB4ADB7A" modified="2015-04-01" version="1">MVVEVKSMEAKKKQQPALNTSKNKETLAAHKKIQVADFISEIKAELKRINWTNPEELKTYTLIVVGATFFCGMGIYFMDLLIQACLWFLESALRLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K841</accession>
    <name>A0A0C1K841_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HP00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000126">
        <property type="protein sequence ID" value="KIC75347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75347">
        <property type="protein sequence ID" value="KIC75347"/>
        <property type="gene ID" value="DB41_HP00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007787">
        <property type="entry name" value="DUF687"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05095">
        <property type="entry name" value="DUF687"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="946" mass="109192" checksum="44AC2472F3EA9A31" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K860</accession>
    <name>A0A0C1K860_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HN00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243945.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75377">
        <property type="protein sequence ID" value="KIC75377"/>
        <property type="gene ID" value="DB41_HN00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1286"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="612"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="2263" mass="250904" checksum="DBFF9DD20757A2FB" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9A3</accession>
    <name>A0A0C1K9A3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HH00300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385235.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75737">
        <property type="protein sequence ID" value="KIC75737"/>
        <property type="gene ID" value="DB41_HH00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="18455" checksum="FEE7330F78A7B6D7" modified="2015-04-01" version="1">MLKLSHKTLIIFSGVIWLAVGSFLLSLGLNFLLHAVQDMRFLEKNNYPLLNLFSSVFSNAENTMVFLIAVGLIIGYSKGRYVLGKAAVKGVERIYTLPNPTYLQNIYDSKYYILLAGMMGLGFSMKYLGIPADIRGLIDVAIGSALINGAMIYFRLAFTKPLEDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9C2</accession>
    <name>A0A0C1K9C2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385176.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75762">
        <property type="protein sequence ID" value="KIC75762"/>
        <property type="gene ID" value="DB41_HG00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7516" checksum="3A5895766F9EDA55" modified="2015-04-01" version="1">MHATDKFFAWQQIGLPEIKPLVHQIDLVTSRCPCCHLQIRAELKENEPFLLGPRLESFINLLMGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9P1</accession>
    <name>A0A0C1K9P1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75887">
        <property type="protein sequence ID" value="KIC75887"/>
        <property type="gene ID" value="DB41_GZ00510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7316" checksum="B56FB0415B56182D" modified="2015-04-01" version="1">MEGTQHLGNLYATLQELFKDKPRIGKGVISSLLGSSMDILTGVIYKKNCKRCSAGVAPKSYGSFATSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA50</accession>
    <name>A0A0C1KA50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GR00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC76002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384853.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76002">
        <property type="protein sequence ID" value="KIC76002"/>
        <property type="gene ID" value="DB41_GR00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="158" mass="17874" checksum="13F51E895E68F2F2" modified="2015-04-01" version="1">MQYAYVYRQSRANFEIFGYKFRLNLIDTLQQKLKIVVDRPVTKSLAVRTLKNIERESSIKAFLTKRVVVITATSAVVVSGLFLPHAVASLAVLTSAYVRSVIAAVGTIVIAYVMANNNLPKLSQAYQDQARQARYLMEEIRNKEDNVAFIFPNNERIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBB0</accession>
    <name>A0A0C1KBB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GC00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384507.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76442">
        <property type="protein sequence ID" value="KIC76442"/>
        <property type="gene ID" value="DB41_GC00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.837"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="644"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="742" mass="82982" checksum="68D5EB6CAAEBAD63" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC07</accession>
    <name>A0A0C1KC07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">miaA</name>
        <name evidence="9" type="ORF">DB41_FH00130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76632">
        <property type="protein sequence ID" value="KIC76632"/>
        <property type="gene ID" value="DB41_FH00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.667"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="67"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="343" mass="39215" checksum="BEF5CD8F533BB2EF" modified="2015-04-01" version="1">MACGTLEKEEIEQIFINFAIEAQKQLPTALPQNKKRVIIIAGPTGCGKSHFALQLARKIQGEIVSADSMQVYKGMDIGTAKPTIEERQQISHHLIDICHLTDSFNVVDFCYEARQAFQRIHNRDKVPIVVGGAGFYIHSLLYGPPLGPPSIPEIRQALEEEYDRLGPDALYARLQQLDLHYASGITKNDKQKIVRALEIITLTGEKVSKLSWKGRHKLQNYDFRCWFLFRPRPHLYHRIENRCDQMIEGGLLEEVQGLLKKGLLANSSAAQAIGYKQAIAYLASAKRPDDYLQFVETFKRASRNYAKRQHTWFGKEPLFNWIDMDLYDTKMIADLISKDFESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4T9</accession>
    <name>A0A0C1H4T9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KJ00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386369.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72529">
        <property type="protein sequence ID" value="KIC72529"/>
        <property type="gene ID" value="DB41_KJ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="170" mass="19828" checksum="ACEC091A5F104AB1" modified="2015-04-01" version="1">MTEKKNSPEGIELRYSDLSDGKYLKQWLLDPSVARWFPMFDEVEIDDAVARWIGFSRYKCSLTATKEGVPCGITTLYLQPYRKLAHQCEFGIIVAPEMRGQGVGTLLISNLSHMAKENFKIEVLHLQVYAENPAIHLYTRMGFREFGRQTHWIKEKDGFYVGRVFMERWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA86</accession>
    <name>A0A0C1HA86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71738">
        <property type="protein sequence ID" value="KIC71738"/>
        <property type="gene ID" value="DB41_AM00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="5463" checksum="59DDF4289CCE3AF6" modified="2015-04-01" version="1">MHAENNFFPFSIYPEQKVSEKLLFWIERKPIKFYYYYLQAINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAM0</accession>
    <name>A0A0C1HAM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IN00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000145">
        <property type="protein sequence ID" value="KIC74449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243994.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000145.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74449">
        <property type="protein sequence ID" value="KIC74449"/>
        <property type="gene ID" value="DB41_IN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="452" mass="51566" checksum="C4C85AED24A10546" modified="2015-04-01" version="1">MHSISSASIESLPNELLLPILEACTVPSLFSVCKRWHHLLATEVMPSLYKQIGKMHFPQGDVDERAFLIDKIYKLDDGLPEVAKVAAIFKQVFSLATALSPLELEFKWRTEEKKYLTLANYSSYMVNINRLLMWKKLPGGEEFLEQEEIKYLPLERKGELFGGWIEEHGKEITCLNLTEKGLTFLPLEIGLLPQLQALYLSNNHLTILPREIGQLSHLKCLNLNDNQLNTLPAELGQLSNLRRLLLEGNQLNTLPVEIGRLSQLRELSLEVNQLISLPAEIGQLAQLKILNLNYNQLSTLPAEIGQLSKLQKFSLEGNYLITLPAEIGQLSQLQTLSLESNQLAFLPIEMGQLAKLKDLDLKDNQLTHLPKEMGQLTYLESLVVRCNRLTSLPKEICQLLQLRRLDIRYNQLTFLPVEIEQLDNNGNVILDLIGNPFESIPHVLKERFHLWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBF1</accession>
    <name>A0A0C1HBF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IF00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385883.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74759">
        <property type="protein sequence ID" value="KIC74759"/>
        <property type="gene ID" value="DB41_IF00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="552" mass="62920" checksum="3E8A4B1B8081B689" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBH0</accession>
    <name>A0A0C1HBH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KT00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000198">
        <property type="protein sequence ID" value="KIC72128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72128">
        <property type="protein sequence ID" value="KIC72128"/>
        <property type="gene ID" value="DB41_KT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4408" checksum="05A638E72CA9BE89" modified="2015-04-01" version="1" fragment="single">PDLNPIETFWANFKKIVAANLSKFSTLAQTIDYSFLSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBY0</accession>
    <name>A0A0C1HBY0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">pheS</name>
        <name evidence="16" type="ORF">DB41_IB00570</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74924">
        <property type="protein sequence ID" value="KIC74924"/>
        <property type="gene ID" value="DB41_IB00570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1492"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="15">
        <location>
            <begin position="124"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KIC74924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="356" mass="40940" checksum="E1AE36518BE35348" modified="2015-04-01" version="1">MTLLFFLFYFLRKIVHSSIQAIHSDFTADIAAVKTTAEIENLKIKYLGKKGFIQNLMKFLKEVNPEQRPAFGKEINELKEDVLHQIEEHEKQLIAKEEDQQLAQEKIDITLPGRRPPLGRKHIITQALDSILDILVGMGFSVQYGPDIDTDYYNFEALNFSSDHPARDMQDTFYITPDVLLRTHTSNVQVRVMEAHQPPIRIITPGKAYRNETITARSHVFFHQVEGLYIDKGVTFADLLATMQEFFKQLFRREIETRYRPSYFPFVEPGLEVDISCLSCKGKGCQLCKHSGWLEVAGAGMVHPEVLKNGGIDPEVYSGYAWGIGVERMVLLKHGVKDIRLFTENDLRFLEQFTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC75</accession>
    <name>A0A0C1HC75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HY00250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385556.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74999">
        <property type="protein sequence ID" value="KIC74999"/>
        <property type="gene ID" value="DB41_HY00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1419"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="578" mass="65244" checksum="72476F7AA65AB63A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCI9</accession>
    <name>A0A0C1HCI9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HPt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HW00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385493.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75109">
        <property type="protein sequence ID" value="KIC75109"/>
        <property type="gene ID" value="DB41_HW00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="1">
        <location>
            <begin position="130"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="212" mass="24548" checksum="4BF72F2A5D676B8D" modified="2015-04-01" version="1">MQVLCVDQDKNFCNFIKREGEALGVRVNGVMTFDQAQERMRDQSSYACIFNSSHCEQLATVDQLSFSLAYDDLPSVSLLQELKATQKVRYIAGKMMSSEEARYLLAQLCQLEAYEKLKGDWVAEIPEQLMKAYEISSYEKLGIIEKLIKNNSHQPAWEELQFIVHKIAGSAGFYGRFMACEICKKMETHIKQKEYALIDLNSFYRQLYLYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCJ1</accession>
    <name>A0A0C1HCJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75114">
        <property type="protein sequence ID" value="KIC75114"/>
        <property type="gene ID" value="DB41_HW00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7647" checksum="10A396CD0D2B84CC" modified="2015-04-01" version="1">MRDDDSPYGLFKSQSDYDQRKSVKLMIINGLAFTLDFLYKNIQELILSLNPTMRHVLLVLVPFGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCL1</accession>
    <name>A0A0C1HCL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase, IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HU00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000131">
        <property type="protein sequence ID" value="KIC75144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75144">
        <property type="protein sequence ID" value="KIC75144"/>
        <property type="gene ID" value="DB41_HU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="132" mass="15063" checksum="2BE15B5ED8BE40B1" modified="2015-04-01" version="1">MCVVNALQWLPQREKWHLQSIIEVRSERKVADKVEQAIRYYGSSRKAGAKEFAKWIQAHWAIENSLHHVMDVVFKEDASLSDVGFSAENMALIRRLATNIIRTMDSGRGITDARQNATYAPNYLRELLGSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD63</accession>
    <name>A0A0C1HD63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KD00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72703">
        <property type="protein sequence ID" value="KIC72703"/>
        <property type="gene ID" value="DB41_KD00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6772" checksum="91621EA577B825EC" modified="2015-04-01" version="1">MIFYDIFMTLFTTKNLKISHIKNDREDNPSLFWLLYNFFFTLQRMLKTHIYTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD92</accession>
    <name>A0A0C1HD92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsI</name>
        <name evidence="8" type="ORF">DB41_HN00110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385358.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75379">
        <property type="protein sequence ID" value="KIC75379"/>
        <property type="gene ID" value="DB41_HN00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1288"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="14598" checksum="531EC84E397FDDFC" modified="2015-04-01" version="1">MEEFVATGRRKTAVSSVRIRPGSGNIDINGRTFEEYFPLEIQRRTILAPFEKLNGNGRHDMIIRVKGGGVEGQVIASRLGVARALLLIEEGLHQDFKSQGFLTRDARKKERKKYGHAKARKRFQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE13</accession>
    <name>A0A0C1HE13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HI00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385273.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000119.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75649">
        <property type="protein sequence ID" value="KIC75649"/>
        <property type="gene ID" value="DB41_HI00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="286" mass="32241" checksum="41CDAE9083BA4B9B" modified="2015-04-01" version="1">MKNCLAYLLLVLPSLLSGVEFKPWYPNPLQVHGELAYHFQSYASVDAVSGHYSSKDQLINGSLLVAYDPYCLQLETAFADTKKCSFNCTHIALTARYLFLDDNLGDPVSLSMGLSVKRAWKKAVKDISLFYHGRNEAFLHAAIGKQNIEGLAWYSRWWGVVGIGTADCWTPWVVANAAYEWNRSYLHRICVYINCLWGLGKQKLTAGSFGGYGRIDHRSIDLGLRYCYEFAYSGLLSIDYARRVYAHNFPKAVNLLTISYIYPFGPKGTAYVLKAYSLLTDKAPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEI3</accession>
    <name>A0A0C1HEI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative outer membrane protein TolC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tolC</name>
        <name evidence="2" type="ORF">DB41_GZ00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75844">
        <property type="protein sequence ID" value="KIC75844"/>
        <property type="gene ID" value="DB41_GZ00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="416" mass="47457" checksum="21BC3E66A46C8DC1" modified="2015-04-01" version="1">MLIFKVLVCYLLAASSFLYGILTLEKCYDLALNYSETLTVAELKALIEQDRTREVYGLHLPQMTAQIDFLTKGNLKRVRHQERTKNARVSLVIPLYNFGHSTHTINAQKSREESSFIKMTTARQKILHATNHAYFTLAEAQKIILIIKESIRSLKGQLRISKDFAEQGLIHENEILVVELELALKQQDLLQAQSNVSIAATQLNRLIGYPLDRQTVVIDLLEPIPYHANLNQLLEEARSNHPHLKALQADIKAARFTLTAEKGKLYPSIYGYTNYSTSDNYALPYRHGLDAGIGIQLSLYDGGSTWAKLRRLRKEMCELEQQYIAAEKDMELYIRTAFSTVENTIQKIPLALKAIQVAEHNLTLVKNHFAEGLITNEDLMIDEEKLLHARHNYYQTLCQYYKAKADLAYAAGLNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEY2</accession>
    <name>A0A0C1HEY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Type II secretion system protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xpsF</name>
        <name evidence="11" type="ORF">DB41_JM00160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73263">
        <property type="protein sequence ID" value="KIC73263"/>
        <property type="gene ID" value="DB41_JM00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1793"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001992">
        <property type="entry name" value="T2SS_GspF/T4SS_PilC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00874">
        <property type="entry name" value="T2SP_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="10">
        <location>
            <begin position="70"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="10">
        <location>
            <begin position="271"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC73263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="402" mass="44715" checksum="4A7EB1AC00D3B42B" modified="2015-04-01" version="1">MALRRANFMPLYSYEALDSLGKKRAGLIEAQTEKEAKEKLRSQGTMLKKLALRTTISKKQNLKGDTLLAFTLQLSQLVSAGVPLYESLLALEEQYRTDSCHRVVLSLCEQIKAGQSLSQSMGNFPDSFDKLYCSMITAGEAVGALDIVLDKLSQLLQKQNKLKKQIITAMVYPAILAAFSFLIILMLLGFVVPSIEGIFVDRQLNGFTEFVLGMSRGFRSYWWVALPSALAGIIYLVHFLRSLQGRLWLERNMIKVPLLKTLIIQTCVARFCRTMGTLQQGGLPVINSLRISREVMHNIVLEEEVKKAEGKIIEGSSLSAELMHSRYIPKLVPRMLAVGEESGNAIAMFNKVADIYENEIEKSLERVMALAQPVILIVMGTIIGVVLLAILLPLTDVSSLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HF31</accession>
    <name>A0A0C1HF31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GP00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76034">
        <property type="protein sequence ID" value="KIC76034"/>
        <property type="gene ID" value="DB41_GP00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="572" mass="66289" checksum="410570C1789B7256" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFW7</accession>
    <name>A0A0C1HFW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SEPHCHC synthase</shortName>
            <ecNumber evidence="3">2.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthesis protein MenD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">menD</name>
        <name evidence="5" type="ORF">DB41_GL00150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="2.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="3">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPP enzyme family. MenD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243891.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76274">
        <property type="protein sequence ID" value="KIC76274"/>
        <property type="gene ID" value="DB41_GL00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.949"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="PTHR42916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004983">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="4">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="532" mass="60262" checksum="7DACB5A3EDFFCA32" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGV7</accession>
    <name>A0A0C1HGV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76554">
        <property type="protein sequence ID" value="KIC76554"/>
        <property type="gene ID" value="DB41_FN00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="84" mass="10027" checksum="94BBF3754D98CE94" modified="2015-04-01" version="1">MANDPLVQKKVVYQDIAFSNKKWAICFGKKENERRRSYRRIFFLYPHDTFKILKNPCLAFPGKRVIDTHMLVRIPRTLVSNFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHE8</accession>
    <name>A0A0C1HHE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_ET00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383948.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76739">
        <property type="protein sequence ID" value="KIC76739"/>
        <property type="gene ID" value="DB41_ET00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.561"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="84" mass="9560" checksum="C7617CD3F9FF77CC" modified="2015-04-01" version="1">MTEKVSRNDPCPCGSGKKYKNCCWGKKYTKKKLTAKWLNQPAMPNLMERTFGDSIAKTFKQQPPLLHVEKEVSTVEAPSLEKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHP9</accession>
    <name>A0A0C1HHP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EG00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76839">
        <property type="protein sequence ID" value="KIC76839"/>
        <property type="gene ID" value="DB41_EG00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6653" checksum="4C27125593969AF0" modified="2015-04-01" version="1">MEQITLLLSLFLTYLVGKALAELMIPANYHILRGYPIIYWTKNQSKKIAWKYEHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI26</accession>
    <name>A0A0C1HI26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DP00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383574.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76969">
        <property type="protein sequence ID" value="KIC76969"/>
        <property type="gene ID" value="DB41_DP00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="153" mass="17958" checksum="389AD1B06762C3ED" modified="2015-04-01" version="1">MVNKTVYLYVLVSLAAGYALLNFFIFPFSNPSVPLLEQARAAYQEAAQSNNFFHRRQALNRLLMIYHSLDKLYCPLQGNGVLYSNLAETYYNLEQYPWAAFYFYQSKRLRPRDLEVEFKLKETLAKLKIPPTQSPSSFKKFFSFTFIFLYPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIV7</accession>
    <name>A0A0C1HIV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CS00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77199">
        <property type="protein sequence ID" value="KIC77199"/>
        <property type="gene ID" value="DB41_CS00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5669" checksum="D05E2F1D95E51737" modified="2015-04-01" version="1">MFYPYPFAHYQRNSKVRSLISIRGNWIYLSMIKLMLSRINKAKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ70</accession>
    <name>A0A0C1HJ70_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rmlC</name>
        <name evidence="4" type="ORF">DB41_IJ00390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385951.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74568">
        <property type="protein sequence ID" value="KIC74568"/>
        <property type="gene ID" value="DB41_IJ00390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1619"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="182" mass="20829" checksum="20FBAAD28023FBC4" modified="2015-04-01" version="1">MQVLGTSIPEVKIIEPQVFGDARGFFFESFNLTMFREKAHIRDTFVQDNHSHSPKHVLRGLHYQIHQPQGKLVRVVSGEVYDVAVDLRKHSPTFGQWVGLILSAQNKRMLWIPKGFAHGFLVLSDQADFLYKASDFYDPASERTIIWNDPDLAIEWPLQGDVPILSAKDQKGNLFKHAEVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLV3</accession>
    <name>A0A0C1HLV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HN00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385356.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75378">
        <property type="protein sequence ID" value="KIC75378"/>
        <property type="gene ID" value="DB41_HN00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="7664" checksum="44B40686AFD31CA7" modified="2015-04-01" version="1">MQLSPPLGRSSRIYHQSLHTEAEGSVSVVSACSNIEENRTEPSLDPFSPPISSAKKSAQEENLLTQRLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMY8</accession>
    <name>A0A0C1HMY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HH00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75713">
        <property type="protein sequence ID" value="KIC75713"/>
        <property type="gene ID" value="DB41_HH00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002146696" evidence="1">
        <location>
            <begin position="22"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7119" checksum="77939D4C3B2AB6C7" modified="2015-04-01" version="1">MKQAIKFFSSVALFVSVIALTGCCGNRAGYEPCAKPCSPQPYYTKPYVKNAPRPCAPAPVCDPVCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNE4</accession>
    <name>A0A0C1HNE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384949.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75838">
        <property type="protein sequence ID" value="KIC75838"/>
        <property type="gene ID" value="DB41_GZ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7637" checksum="DA363B85687750AE" modified="2015-04-01" version="1">MKKNIGTADRILRFTLAFLLGGLAFQFKSWLLGVMALFTLYEALASWCILYHLIGKNSCSLPTKPKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPE4</accession>
    <name>A0A0C1HPE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 14" type="primary">yidC</name>
        <name evidence="14" type="ORF">DB41_GN00180</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384794.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76108">
        <property type="protein sequence ID" value="KIC76108"/>
        <property type="gene ID" value="DB41_GN00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.979"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01900">
        <property type="entry name" value="YIDCPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="678"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="733"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="774"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="838" mass="95373" checksum="E74FDAB99B1EA9AA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPF1</accession>
    <name>A0A0C1HPF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GN00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384801.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76113">
        <property type="protein sequence ID" value="KIC76113"/>
        <property type="gene ID" value="DB41_GN00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.985"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021266">
        <property type="entry name" value="Kdo_hydroxlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11004">
        <property type="entry name" value="Kdo_hydroxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="296" mass="34296" checksum="D53363BE0D9E5483" modified="2015-04-01" version="1">MQEVIKTFDITSFENPLAEEIKKDAIQTLEQGKVVYFPHLTFNLHEDELQFLSPQVVAPKSKNISYDVIRDRLGGTICRGEEEQKLKNMMQRYALQSRLFIEKLFPHYKGHLNQARTSFRPAEIAGRSSSWRKDDTLLHVDAFPSSPVKGKRIMRFFSNINPAQQPRVWKLGEPFSEVVQKFGVKLKKPFPGLAWLLKVVGITKDYRTLYDHYMMSLHDLMKGDKEYQKNAKQQEVLFPPGSSWIVYTDQASHAALSGQYVMEQTFYLPVESLQDPETSPLRVLERFYGQELIESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQF7</accession>
    <name>A0A0C1HQF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GD00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0236 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76423">
        <property type="protein sequence ID" value="KIC76423"/>
        <property type="gene ID" value="DB41_GD00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.863"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009620">
        <property type="entry name" value="UPF0236"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06782">
        <property type="entry name" value="UPF0236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="208" mass="23809" checksum="89BDBE378126C0A2" modified="2015-04-01" version="1">MARGKDRANRFYAGSIGTAEQAGQQMLECALIAGLKEGSYVHAISDGAPWIAEQIKLKFCNRSGHLIDFYHLCEYLSEAAIWCNIFAPIKWLEESKEKLKAGKSREVFKEIEIKFKALDHPEQENGLVRCYRYMEKRLDMMNYKSALDKGLPIGSGEIESSHRHVVQKRLKIAGAWWKKENANAMLSLRIGRLNGYWEAYWNSYKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR96</accession>
    <name>A0A0C1HR96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FD00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384075.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000066.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76643">
        <property type="protein sequence ID" value="KIC76643"/>
        <property type="gene ID" value="DB41_FD00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="472" mass="53805" checksum="0713D6E505607A16" modified="2015-04-01" version="1">MNISLNDPYLKNLSPPREPKQPPPTPSRNSASRGKHPRNEEKDLLLPPFKLPKLEQEDTPLPKTRLGIKLGFGASSNEPENLPFTRCTKRSRVIEELNDDEKDGDSANCKQRKLNLDETALPQNKPALKIGFGTSSSLPPSPFAGTKSAMFSKSSVLARKLFSIPSAGKASEEPQRLQFSLPPKEEKKQNVLAQSALLPLSYYKQELVKPSLELLPDDKKGLLYEGPDLEDKLGKILIKKGERLILTYLGHGDFHHVWKVENVDLVIKILRDDTLSEMKRKQSIITTERAYKKLLNLTPQMKGISVAHIYNIEDIWERGYYIYEYIAGETAFKDIKDVFSQIFANPDYYIADLSPGNVRTKEDHSVIIDPYDEGEIPLQHQAIDLARVIIQWIKHEIKVAPSFAPNIAESETQEDHQQFYCELNKFYKETEAYLNEMSAKNDALWQETKNKIQDKLEAGIKKENFIIESIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRZ4</accession>
    <name>A0A0C1HRZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DZ00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383705.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76883">
        <property type="protein sequence ID" value="KIC76883"/>
        <property type="gene ID" value="DB41_DZ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.424"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="244" mass="28197" checksum="D97BCB20EEA5A4A1" modified="2015-04-01" version="1">MNEQALKNRLKIISIEKGIHFNECWKKLLLERFLVRLSHSTHARNFIFKGGSLLAYFLHIGRETTDLDFLLTNMKAGQEETKQAIAQIAAIELKDGFSFKYAGIDILEQPHMDYSGYRVHLKATFGRMKDKIHIDVGVGDIVKPFSQDIYLSQYKGHPLFEEEVSLMVYPPETIFAEKLETVISKGTANSRMKDYHDLLLLIRDAKLINFKILKDALTDTFKNRKKRLELLSFDEPGLKSLQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSK6</accession>
    <name>A0A0C1HSK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DI00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243768.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77043">
        <property type="protein sequence ID" value="KIC77043"/>
        <property type="gene ID" value="DB41_DI00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="9973" checksum="BAEAA5E978EC22B8" modified="2015-04-01" version="1">MLVCEVLNDDGVLKGWCPIGGGIEFSESAGEALKREIYEELGCNLVITGEPIVCKNIFEHHGIKGHEIIFAFLIKLSDKTIYTKKSFSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HST5</accession>
    <name>A0A0C1HST5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_1</name>
        <name evidence="3" type="ORF">DB41_DC00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243761.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77093">
        <property type="protein sequence ID" value="KIC77093"/>
        <property type="gene ID" value="DB41_DC00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.224"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="394" mass="44597" checksum="E57B4F453DD00B75" modified="2015-04-01" version="1">MHPITSASIESLPNELLFPILEACVVPSLFSVCKRWSHLLATEVMPSLYKQIGKMHFSQGDINKQALIVDKIYKLEDRPSEIEKVKAIFKQAFALSKSLAPAELEFKWKTQEKRYYTLANYSSYLININRLLMWKRLPGGGEFLDQEKIKYLPLEKQGELLRGWIKENCENLTLLDLFSEGLTYLPPEIGQLSQLTRLRSDYSQLTILPAEIGKLSQLQKLELNQSQLASLPAEIGQLSQLRGLYLDQNQLTALPVEIGQLSQLQTLELNESQLASLPAEIGQLSKLQCLILDQNQLTALPIEIGQLSQLQWFYLNQSQLIALPTEIGQLSQLQTLELNQNQLTALPTEIGQLSKLQKLELKQNQLTSLPTEIGQLSQLQRLFIGHNQLTTIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT42</accession>
    <name>A0A0C1HT42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">asnS</name>
        <name evidence="7" type="ORF">DB41_CO00070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383095.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77238">
        <property type="protein sequence ID" value="KIC77238"/>
        <property type="gene ID" value="DB41_CO00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.40"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="152"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="467" mass="53079" checksum="F20574D99E4737BB" modified="2015-04-01" version="1">MRVKIKQLKYPAPGVPSLLGQEVTIKGWVRTVRNQKTFSFAEVNDGSTLSNFQVILNPDLPDYEKILSHLSTGVSVAVVGKIVENPGKDQAWEMQAKSLTIIGTCDPEVYPLQKKRHSFEFLRSIAHLRPRTNTLGAITRLRNSLAFATHLFYQQKGFLYLHTPVITASDCEGAGKMFRVTTLDPSATPHLPNGQVDYSQDFFGKPAYLTVSGQLNGEIYASALSDVYTFGPTFRAENSNTSRHLAEFWMIEPEMAFADINDNMDNAEEYLKFVLKYALNNCAEDMEFFDKHVSTGLIERMQHVINTPFERATYSYAVRILEKSGKNFEYPVKWGLDLQSEHERYLAEEFFAKPVILTDYPKQIKAFYMRDNSDNKTVAAMDVLVPKIGEIIGGSQREERLDVLEHKLKAGGLSPDDYWWYLELRKYGTVPHAGYGVGFERLIQFVSGMENIRDVIPFPRYPGKAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JID9</accession>
    <name>A0A0C1JID9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CF00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000251">
        <property type="protein sequence ID" value="KIC71150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71150">
        <property type="protein sequence ID" value="KIC71150"/>
        <property type="gene ID" value="DB41_CF00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="333" mass="36320" checksum="2E4DE047CCE7C90D" modified="2015-04-01" version="1" fragment="single">MVHWLNRLFGCFRHMAGARLYEIKVEGLEGRFFGGVSKAHEGDSESNTSEEPRSGSSGEGSEVQTVVGDGMAFKEDNFLTSANLCRWIIDYNEIQVGKQIGLGSYGVVYPGQVEGRRRGGEAVHQAEARRAAHARVPRRDGLPLGAAPPQHRALHRRVREEAQPVHRDRVHEAGLAQGHPGQQPDQARVEAEDAHAAIGGAGHQLPPLAPPGHRAPRPQALQPARGRELEREGGRLRVRAHQGGERHHDPLRHALLDGAGDHPRGEVRRAGRRVLVRRGHVAGGDAQGALCRAQLHGRVARRARGQAAADPQRLSARVQEGDEEVLARQCRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL78</accession>
    <name>A0A0C1JL78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_AA00210</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386566.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72040">
        <property type="protein sequence ID" value="KIC72040"/>
        <property type="gene ID" value="DB41_AA00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2094"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01485">
        <property type="entry name" value="RecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004586">
        <property type="entry name" value="RecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF23">
        <property type="entry name" value="PTHR11070:SF23"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="10">
        <location>
            <begin position="1"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="11">
        <location>
            <begin position="482"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="21"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC72040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1168" mass="135516" checksum="299D81C3CECDB116" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLF6</accession>
    <name>A0A0C1JLF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KV00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386548.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000200.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72095">
        <property type="protein sequence ID" value="KIC72095"/>
        <property type="gene ID" value="DB41_KV00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="23650" checksum="98CA5605EB40BE21" modified="2015-04-01" version="1">MHPISPASIESLPNELLLPILEACAVPSLFSVCKRWHHLLASEVMPSLYKKIAQLHFPKGNANTQRTLMLTKVYQLNPALTSTEKVYQVFKQVLTLAKSISPLEFKEKTEEKRGLTLANYSSYLLNISRLLLWKKLPGGEEYLSREEIKHLPLEKKGELFRDWIEENCKNITALDLSKVSLTYLPPEICQHAFKLLLTQLDIRYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMM4</accession>
    <name>A0A0C1JMM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein soc-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">soc-2_2</name>
        <name evidence="3" type="ORF">DB41_AF00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244097.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000206.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71816">
        <property type="protein sequence ID" value="KIC71816"/>
        <property type="gene ID" value="DB41_AF00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2145"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="632" mass="71118" checksum="6A56EEFE16A0A0F8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMN5</accession>
    <name>A0A0C1JMN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">prfB</name>
        <name evidence="6" type="ORF">DB41_KJ00050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72530">
        <property type="protein sequence ID" value="KIC72530"/>
        <property type="gene ID" value="DB41_KJ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1922"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="5">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="326" mass="36990" checksum="BB4E68BC513711EA" modified="2015-04-01" version="1">MEKPSFWENHEKAQLVIEEANSLKAWIVPYQNCKQLFCDLKELLPEAYASGDEALVNELVQELDGVEKKLNDLEIRKMLAGELDNKNCYLSINSGAGGTEACDWALMLSRMYQRWAVKRGWKVELIDRVEGDVAGIKSITFKFDGEFAYGYAKAEKGVHRLVRISPFDANAKRHTSFASVDVTPEITDDIVIDIKPEEIRVDTYRASGAGGQHVNKTDSAVRMTHLPTGIVVSSQTQRSQVQNRESCHKMLRSKLYEKEVTERENALKALSGEKKEIAWGSQIRNYVFQPYTLVKDTRTKHESGDIQAVMNGELDDFVNAYLKEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMT4</accession>
    <name>A0A0C1JMT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">shoC2_3</name>
        <name evidence="4" type="ORF">DB41_KI00140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244048.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72570">
        <property type="protein sequence ID" value="KIC72570"/>
        <property type="gene ID" value="DB41_KI00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1907"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="10"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="647" mass="72079" checksum="EDFD2DBAB5308A5F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNC8</accession>
    <name>A0A0C1JNC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72041">
        <property type="protein sequence ID" value="KIC72041"/>
        <property type="gene ID" value="DB41_AA00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5150" checksum="C957C235D458BB03" modified="2015-04-01" version="1">MEAKTNKLEKMKHSKIRGLIGSKRFALEELSEGFFIFFLVFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP11</accession>
    <name>A0A0C1JP11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative TolQ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tolQ</name>
        <name evidence="9" type="ORF">DB41_KP00030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386455.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000195.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72271">
        <property type="protein sequence ID" value="KIC72271"/>
        <property type="gene ID" value="DB41_KP00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1996"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="121"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC72271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="249" mass="28281" checksum="74EF81E27F5398FD" modified="2015-04-01" version="1">MNVNIFIATNPFYEAYIHSDFLGKLIFIGLLLLSMITWIILLHKIWQTYQARKQAARFYDIFQLQKQNPLNLDCEAASRVKNSNPYMDLYSLLKKQTMEIFNKNKYVMQKNREAEQSVPFLSLTDIDFIQSSLATQIAHQTKNLEKNLFILSTVVSLAPFLGLLGTVWGILTSFSDFQVQASGSTPQMVLGGLSLALATTVLGLIDAIPALIGYNYLKHAIRDFEIEMESFANEMLGAVELQYRKVDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPN4</accession>
    <name>A0A0C1JPN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KK00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386398.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72491">
        <property type="protein sequence ID" value="KIC72491"/>
        <property type="gene ID" value="DB41_KK00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1952"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="48754" checksum="EE05E6D52A2D4020" modified="2015-04-01" version="1">MLANANLLKFSFWVWPYFAMLVIGLTFPSDGNHGMMTPKSGLFLGCFCLMIFYSFFRVRLTMHQLRLICFACISLSFLLIWMFIGHWHKNEWLNSGFDQFKIFSITIATVIMTLNLVHEDLTTKEKILKVIIYSNFAYSTIKVTVVVLHLLKIIDMFHLLDLLGVRYMSMAMLQGNLSRLQTSVDIITPFLLLFVLQGNRLNLGLSKNFKWLFLLITLPAIFLSFSRFLYGVVGISIILYAFTLNFKGFFRMAILTTLVAILGLSWIGIEKVQILIYERFFSHDNQMSDQVRVDQINALMEELDIYPLLGKGLGGYVEKLVRGGDLHHSYEVQWIAFLMQFGILGFIILMIPVAIIAYKLFAPPFNRLKLAFLGLFGVWLLSGFTNPFLISLTSGIVYSMFLLVSDILKTLSQQERVLVSWYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPP2</accession>
    <name>A0A0C1JPP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JQ00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386198.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73160">
        <property type="protein sequence ID" value="KIC73160"/>
        <property type="gene ID" value="DB41_JQ00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="301" mass="32412" checksum="2CAE758E64A95F5B" modified="2015-04-01" version="1">MRAILLSLLAAGGSASSNLFFRKNSQNSSASNPTTYLLAFYLTSFLFSFILYPTIFFESLNLKMLGIGALVGLLNIALMFFTSCALHKGPAGLTFAFQNTSAVFPGMILFALFGSENGFSYSYQKLLGILLVIGGLFLGAKGEAKGSLKSLYPWLKYALACLAVQVLALTFMQARCVICPTVETAAPSYALVSKEDVSFMLGQFGVACLIQAIYFLRQMNTWTTTTTMYGVLAGLANFASTALLLLATKWALPIEKGVLFPCFAVGTIIACNIWANRLYGEKFNYTSNAICAAGIILSLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPS2</accession>
    <name>A0A0C1JPS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_JN00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000170">
        <property type="protein sequence ID" value="KIC73195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73195">
        <property type="protein sequence ID" value="KIC73195"/>
        <property type="gene ID" value="DB41_JN00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="217" mass="23499" checksum="061416B7B08E6CFE" modified="2015-04-01" version="1" fragment="single">HSNLGQIYKGRGNLDKAAEYSNKALTISVKLFGENHPQVATNYSNLGAVYKERGNLGKAAEYSNKALTISVKLFGENHSSVATHYNSLGQIYRAQGNLGKAVEYSNKALATNLKLFGENHPSVASCYSSLGAIYQAQGNLKQAKKSTNLKQAEEYAKKALVINLKSLGENHPNVAICYKNLGQIYKAQGNSDKAAKCDNKARASGHCSRQFRQGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQU8</accession>
    <name>A0A0C1JQU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_JG00050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244019.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73565">
        <property type="protein sequence ID" value="KIC73565"/>
        <property type="gene ID" value="DB41_JG00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC73565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="311" mass="34639" checksum="37863881C0B2AEDC" modified="2015-04-01" version="1">MINVLSVQNLTKIYPGKIPFTAIDKISFDLKKGEILGLLGPNGSGKTTTIQMLLGTLAYTSGAIFYFQQDFAQTRSEILEKVSFASTYTSLPWILTVKENLEVFGLLYGLTRKESAIKFDPLLERFGILGKRNQRVASLSAGQVTRLMLVKAFFTDPQVVLLDEPTASLDPDIASDICSFLLEQRDKKGLSILFSSHKMEEVMEVCDRTIFLKEGKIIADDLPEKLAKSISAVHVKLCVHAGLNRTIAVAANAGFKYSVDHRNIEILIEEDKIPAFLHTLSKEGVNYATIKIKEPSLDDFFHHIAKKNNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTL4</accession>
    <name>A0A0C1JTL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IN00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000145">
        <property type="protein sequence ID" value="KIC74450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74450">
        <property type="protein sequence ID" value="KIC74450"/>
        <property type="gene ID" value="DB41_IN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6597" checksum="7B52B127F80F2E22" modified="2015-04-01" version="1">MRQKEPFFSNKAKNQSHSFSHTKIAASLNPQNLLLLLNAWKAPALSLNLSGKKSVVDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTY1</accession>
    <name>A0A0C1JTY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative periplasmic metal-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_IJ00310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74560">
        <property type="protein sequence ID" value="KIC74560"/>
        <property type="gene ID" value="DB41_IJ00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1612"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="235" mass="26894" checksum="16C76DC05E220891" modified="2015-04-01" version="1">MPAGASAHTYEPTPKQMLEATQADLWFYVGEGFEPKVKSALKSYNPRMQLIDLRQNLDLISYESKHPHHCCHSQENSYDLHYWLSPIQAKIQATTIAEALIKTYPENALLYQSNLAHFHQELDHLHEEIHTLLSKPHNPVLMVSHPAYAYFCREYNCRQLSIEFEGKDPTPQQLTRLIKEAQSNHIKTIFVQVQYSSKGAKLIAAQLGARLVNLNPYAENYLESMREIAKAFGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTY9</accession>
    <name>A0A0C1JTY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74565">
        <property type="protein sequence ID" value="KIC74565"/>
        <property type="gene ID" value="DB41_IJ00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4640" checksum="7F5BBB9762D1FBDD" modified="2015-04-01" version="1">MQLSISAGIDGEIQDDIYHLKNLTSRLYAFELVFMPFHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUI5</accession>
    <name>A0A0C1JUI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inner membrane protein YbaL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ybaL_2</name>
        <name evidence="6" type="ORF">DB41_IF00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385881.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74755">
        <property type="protein sequence ID" value="KIC74755"/>
        <property type="gene ID" value="DB41_IF00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1551"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="492"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="562"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="648"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="725" mass="81096" checksum="33757D0F2167FDBC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUS3</accession>
    <name>A0A0C1JUS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
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            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000139">
        <property type="protein sequence ID" value="KIC74835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385871.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000139.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74835">
        <property type="protein sequence ID" value="KIC74835"/>
        <property type="gene ID" value="DB41_IE00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1544"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="777" mass="88630" checksum="D42421EF4E71217C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV09</accession>
    <name>A0A0C1JV09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042240136.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74905">
        <property type="protein sequence ID" value="KIC74905"/>
        <property type="gene ID" value="DB41_IB00380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="109" mass="13011" checksum="1EBCAFE41791EAC8" modified="2015-04-01" version="1">MQLFLLKINRYVEQFFFQAWWVILFGLFIYMLLEQGMKVRDKEYATLQEHYQELEKQKKEAYALQEKLLIEINSQSDPAWVEQVLMKGLGLVPEGQIKVFFDKSMASKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV25</accession>
    <name>A0A0C1JV25_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplT</name>
        <name evidence="7" type="ORF">DB41_IB00580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385742.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74925">
        <property type="protein sequence ID" value="KIC74925"/>
        <property type="gene ID" value="DB41_IB00580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1494"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="118" mass="13613" checksum="4EAF24F8EBC3E750" modified="2015-04-01" version="1">MVRVTNAVASHRRKKRLLKRAKGFFGDRKNHLRLTSDAVNKALAYNYRHRKEKKREFRSLWIMRIGAAAKIHGISYSKFIHGLQKARCDLDRKMLADMAIRDPQGFAAVVSHAKQALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW41</accession>
    <name>A0A0C1JW41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HS00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385434.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000129.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75310">
        <property type="protein sequence ID" value="KIC75310"/>
        <property type="gene ID" value="DB41_HS00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1333"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010261">
        <property type="entry name" value="Tir_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05932">
        <property type="entry name" value="CesT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="173" mass="19175" checksum="EEEA4643FAA0ED0B" modified="2015-04-01" version="1">MSFENAKENLKEFGKELGLEGLEFDENNTCILGIDDEFSLHLTYEPNSKRLYLYSPLLDGLPKDNKTKLRLYERLLEGSMLGGQMAGGGVGVAVKEELILIHCTIEMEHAEGNRLRAFAPLYVETVEKWRKTCQEVCDGRDEAHQPDSPSLLGDLSDGPSMGPGGKTPGFIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW63</accession>
    <name>A0A0C1JW63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 9" type="primary">mdh</name>
        <name evidence="9" type="ORF">DB41_HR00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000128">
        <property type="protein sequence ID" value="KIC75335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385420.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000128.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75335">
        <property type="protein sequence ID" value="KIC75335"/>
        <property type="gene ID" value="DB41_HR00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1326"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01517">
        <property type="entry name" value="Malate_dehydrog_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="PTHR23382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="8">
        <location>
            <begin position="158"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="37116" checksum="006240CD858CFEAE" modified="2015-04-01" version="1">MPQPLKRIAVTGGAGQIAYSLLFRLANGDLLGATQPIGLHLLEIPEAMPILQSVAMELEDCAFPLLREIIIGSNADEVFKEIDYAFLVGAKPRGPAMERKDLLNENGKIFVEQGQALNKSANPHVIVLVVGNPCNTNCLITLSHAPRIPQQNFHAMMRLDQNRAVSLLAKKANVNSNEVTRAVIWGNHSSTQVPDFTHVHIKNKPLIDFPISQHWLENDFMSGVRERGSEIIAARGKSSAASAASAAIDAMKAIINPTPLGEWYSSGVISNNNPYGIQENLVFSFPCRTKEDKTYEIVKDLPWHAWIRNKIMASESELIEERTFVKDTLGARLHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXC3</accession>
    <name>A0A0C1JXC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">udg</name>
        <name evidence="12" type="ORF">DB41_HH00130</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385209.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75720">
        <property type="protein sequence ID" value="KIC75720"/>
        <property type="gene ID" value="DB41_HH00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1210"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="322"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="155"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="255"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC75720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="452" mass="50495" checksum="A5AA9621DF366A3A" modified="2015-04-01" version="1">MELLIIGTGYVGLVSGTCLAEMGHHVTCLDINEKKIHQLKQGYIPIYEPGLEEMVKRNVKASRLKFSTSYAEALAKSQVCFICVDTPHQENGEADLRFVHNVAAAIAEHMTDYQVIVNKSTVPVGTANLVSSVIAAGLQRRGVSIDFDVASNPEFLKEGCAIQDFMKPDRVIIGTNKAKVAQIMQEIYSPFMLSHERLMIMDIASAEMTKYAANAMLATRISFMNELAGLCEHLGADINKVRRGIGADNRIGYKFLYPGPGYGGSCLPKDISALRKQADQVSYDTPLIDAVAYVNEQQKQLMGYKIIEYFAKYSGLANKTIAILGLSFKPDTDDMREAPSLVLIQQLLQQQAHLRLFDPVAMENAKKILYAHPAITWCNDEIEAAEGVDAIVLMTEWKQFRFLDFDALLKQMKGRVFFDGRNQYNPLEVVKKGLDYLSIGQKPYYREEVEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXV5</accession>
    <name>A0A0C1JXV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpmB</name>
        <name evidence="5" type="ORF">DB41_GZ00590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385022.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75895">
        <property type="protein sequence ID" value="KIC75895"/>
        <property type="gene ID" value="DB41_GZ00590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1126"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="91" mass="10343" checksum="5733B6BEDCDBF508" modified="2015-04-01" version="1">MSKICTVTGKKPARGYKYTIRGIAKKKKGIGLKVTGKTKRRFQPNLVSKRIWFGDEKRFVTLRLSTQALRTIDKVGVSTIIRRLRAQGHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYV5</accession>
    <name>A0A0C1JYV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KN00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000193">
        <property type="protein sequence ID" value="KIC72382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72382">
        <property type="protein sequence ID" value="KIC72382"/>
        <property type="gene ID" value="DB41_KN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7726" checksum="FBEAC99DFD7F268C" modified="2015-04-01" version="1">MKLILSNEDKKANQSLSRERVANENVIGLLKRFKNIADRYRNRRKRFALRFDLIAAIYNWELNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ50</accession>
    <name>A0A0C1JZ50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dTDP-glucose 4,6-dehydratase, rfbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbB_2</name>
        <name evidence="2" type="ORF">DB41_KK00230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244060.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72497">
        <property type="protein sequence ID" value="KIC72497"/>
        <property type="gene ID" value="DB41_KK00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="304" mass="33812" checksum="F7188440AC8EECA5" modified="2015-04-01" version="1">MIAITGSTGFIGNHLCNSLPFPHKRLVRQPISTIPSQQQFIGNLNNPVDINNFVQQADVLIHLAWVNNPWTSDEDIFSDISHNLLSSLTLFEAYAQANPQGHIIFASSGGNMYQKSSLVSHQESDPPHPWSSYSINKLAVENYLALFCRKYGIRGTVLRISNPYGALLPSTRTNGLIGVIFSKLIDNSTLNIIDSLYSIRDYIHLDDLSHAFHLIIKNPPEKALVQVFNVGSGQGTSLKEVLDTIEAISKRKINVNLLNDSCKPTFSVLSPKLISQTLNWHPKIELKEGLEKMWASIHSALALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ93</accession>
    <name>A0A0C1JZ93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">secG</name>
        <name evidence="10" type="ORF">DB41_HG00210</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385181.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75766">
        <property type="protein sequence ID" value="KIC75766"/>
        <property type="gene ID" value="DB41_HG00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1193"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="98" mass="10715" checksum="2698CA172C584CD6" modified="2015-04-01" version="1">MTFLYYTTMVFFMMLCALLCFVILIQESKSSGLGASFGGEASESLFGTSTADVLKKFTAWLAVIFFAACIILSLWTNAIGRANQAQSMPFTLENTESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZD8</accession>
    <name>A0A0C1JZD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HC00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000113">
        <property type="protein sequence ID" value="KIC75826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385051.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000113.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75826">
        <property type="protein sequence ID" value="KIC75826"/>
        <property type="gene ID" value="DB41_HC00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="203" mass="23321" checksum="17D49D8743F7BF63" modified="2015-04-01" version="1">MLETYPTADYAYIVYLCVAILLTLMFAAITGIIGYKVINQAPSQSPYGKMPLRRASDLSYESKERVLRFLFEMHQYDNRMFNLEKAALCRETRRVFSNAITWYGAIKVDWSFLNKRYPGHYVSWGSLSIYQQEVIRSAHSSLEGFQTEYSSPEAAPSKAEKFYTQAVPGPLYVDMEKKILLGWKIVPLTNLEVLVVQKPKSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZN5</accession>
    <name>A0A0C1JZN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase III subunit epsilon</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaQ</name>
        <name evidence="4" type="ORF">DB41_GW00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exonuclease superfamily. TREX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384918.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75931">
        <property type="protein sequence ID" value="KIC75931"/>
        <property type="gene ID" value="DB41_GW00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1045"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024530">
        <property type="entry name" value="QSregVF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040393">
        <property type="entry name" value="TREX1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13058">
        <property type="entry name" value="PTHR13058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12843">
        <property type="entry name" value="QSregVF_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Exonuclease" evidence="3">
        <location>
            <begin position="4"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="230" mass="26575" checksum="8235CA864A70B517" modified="2015-04-01" version="1">MPRRAIFYDTETTGIKADRDRIIEIAAFDPVNNTSFEKLINPGCPIPAEATAVHNITDEMVAKCASFAQVGQEFIDFCEGDVVLIAHNNDAFDLHFLRQEFGRHQIQMPSWSFLDSLKWARRYRPDLPKHTLQFLREIYQIEANKAHRALDDVIVLHQVFSLMTDDLDMETIFKLINKPRELHHMPFGKHQGVPLKDVPRDYIKWLASSGAFDKAENTELKNCFEKLGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZR4</accession>
    <name>A0A0C1JZR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GV00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000107">
        <property type="protein sequence ID" value="KIC75946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384904.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000107.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75946">
        <property type="protein sequence ID" value="KIC75946"/>
        <property type="gene ID" value="DB41_GV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="249" mass="29206" checksum="1578F145E794DABF" modified="2015-04-01" version="1">MKINEAYRAVYKARNYCDHNQKKSLTQQERKLLWICCTTLQNPTKSTLTLQQSHQLKYLLKRLDALPTKPCDTMHPLCRVFLILLKKIANLCHLRISLSRLENKLEDTFSTYMKIEPNLLEKFIHIKAELDANEDELQAHKILKSIESFCLLSAYSSHINKAFLQGESPQALRRLIYDKTGLKLNKQPLHAKTIEAISKAPQILYKKYCYAHQRGITDLFFKKAFNKKDKNFQTKLNRLHAFKVKKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZZ2</accession>
    <name>A0A0C1JZZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KA00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000183">
        <property type="protein sequence ID" value="KIC72842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386265.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000183.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72842">
        <property type="protein sequence ID" value="KIC72842"/>
        <property type="gene ID" value="DB41_KA00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="199" mass="21228" checksum="12171FA778CF2994" modified="2015-04-01" version="1">MVVNINMTAFTDAAGQTSNVLNTGDITSVISHIDASNATLTNKFIACMQCLSQTLNSDGPFQGKCESYLKEKIFDLAKKKPAEAQEAIKDTTIRYDEKLSSTIKKVKYLSAGVWGLPGGNYVRKLGHHIFETYGNNRNLGTTYLLAGATVTFTRGVSSIFALNATDGGQGAGSANMFIGASLMAFPLLNSIIKATGDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K039</accession>
    <name>A0A0C1K039_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FM00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384266.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76570">
        <property type="protein sequence ID" value="KIC76570"/>
        <property type="gene ID" value="DB41_FM00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="6880" checksum="74CF52DF23BADBDF" modified="2015-04-01" version="1">MELSQTLQANYNLRTRGTGINMPGGVVTILIQILYSLLYASKKPTYLALWKMSLYSTGGILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0M8</accession>
    <name>A0A0C1K0M8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GK00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76301">
        <property type="protein sequence ID" value="KIC76301"/>
        <property type="gene ID" value="DB41_GK00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4689" checksum="D0AA3A9903A722EA" modified="2015-04-01" version="1">MDTKKQHQQKNSSQQSNAKTNSSSQKQESHQQNKNNSTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0T3</accession>
    <name>A0A0C1K0T3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_EK00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000050">
        <property type="protein sequence ID" value="KIC76770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243806.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000050.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76770">
        <property type="protein sequence ID" value="KIC76770"/>
        <property type="gene ID" value="DB41_EK00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="269"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="353"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="395"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="479"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="521"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="563"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="605"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="647"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="689"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="756" mass="85199" checksum="B9DE863060C7323F" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0X5</accession>
    <name>A0A0C1K0X5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">secY</name>
        <name evidence="13" type="ORF">DB41_EI00150</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76800">
        <property type="protein sequence ID" value="KIC76800"/>
        <property type="gene ID" value="DB41_EI00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.498"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="385" mass="42366" checksum="287AC318CA70518F" modified="2015-04-01" version="1">MTVIALGVMPYISASIIMQLVVALWPSLQREIKENAEQGRRKINKYTRGLTIILSILQSAMFAKYAIQMNYSRPGIITGELLDAQIWGMPILFYLLFIFTMTAGTVLLMWIGEQITERGIGNGMSLIITVGIVSQLPTAIGLIIQQLNLNSQEPGAMNFTTVLVLIAIFVVVALGTILVIQGHRRIPLQYARRVVGRKEVQGGNSYIPLKVNYAGVIPVIFASSLLMFPAIIATFAGAGNRLSEIAQWLSPGSTLYILLFVGLIIFFTYFWTATQFRPDQIASDMKKNGAFIPGIRQGKPTQDYLESTMNKITLIGAISLAMIAVLPTIIGRLLGVPATISYFFGGTALLILVGVVLDTMKQIESHLLMKRYEGFMKKGRVRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0X6</accession>
    <name>A0A0C1K0X6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GD00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384567.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000089.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76426">
        <property type="protein sequence ID" value="KIC76426"/>
        <property type="gene ID" value="DB41_GD00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="314" mass="36409" checksum="719A02C84C4638C7" modified="2015-04-01" version="1">MNSLSSPCLTSSSAQSSTPEAHSPGLLPISSISASGRDAINQKIINLVREFNELNMANKKLNKKYCDLEQEKEKYKSKNKKLENKYKTLKIENDKYRTQNAQLSQECTTINTLYHLLLSSPVTNRFKKEHETSGGDLLLHFNNKISTLCNRIELEEIGNKELSLSSQQEKLNIYIHIFNEIKKEIIESLLMDTLIDINTRNEKEPIRDMDRNVYIDKFNFMLRNFRKMGKLLQSLTVKLYPHDPRLQALTRFYYWGSAEPQVIYLAPGDTEKEIFVASSSTTERPIHWKFQEVDTPENIIKKKENSDHSFSQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Z5</accession>
    <name>A0A0C1K0Z5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <shortName evidence="6">UDP-N-acetylglucosamine acyltransferase</shortName>
            <ecNumber evidence="6">2.3.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lpxA</name>
        <name evidence="8" type="ORF">DB41_EH00040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:67812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="2.3.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transferase hexapeptide repeat family. LpxA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383781.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76820">
        <property type="protein sequence ID" value="KIC76820"/>
        <property type="gene ID" value="DB41_EH00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.471"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00387">
        <property type="entry name" value="LpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="7">
        <location>
            <begin position="177"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="287" mass="31390" checksum="FC23A9A948B79967" modified="2015-04-01" version="1">MKKSNIHPTAVIEPGAIIGDKVTVEPFAIIKAHVKLEDGVTIKSHAYIDGHTTIGAGTTIYPFASIGTQTQDLKYKGETTFVKIGKNCQIREFVTINSSCGENTSVEVGDDCLIMAYCHIAHNCLVGNRVIMSNNATLAGHVIVEDCAIISGFVPVHQFSRIGKYAMVGGMSRITRDVPPYTIGAGIPYKFGGINIVGLKRHGFSLKIRQELGKAFKIVYRSKACLEEALLQIERELEPLPEILHFVEFCRSSKRGLLGLEGITNFDDEVAQAEKEAEAEIVAKIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K107</accession>
    <name>A0A0C1K107_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS4 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GB00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243864.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000087.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76466">
        <property type="protein sequence ID" value="KIC76466"/>
        <property type="gene ID" value="DB41_GB00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039365">
        <property type="entry name" value="IS701-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33627">
        <property type="entry name" value="PTHR33627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_5" evidence="1">
        <location>
            <begin position="20"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="98" mass="11525" checksum="FA719F06577FC44B" modified="2015-04-01" version="1">MDLEQLNSIREQLNEWINVFKANLGRSERVHWCRLYISGLILDGERKSIEPMAKRLPGGNEQAIQQFVNQSPWDHAAMQQQLAKHMAQSMRVKKEYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K122</accession>
    <name>A0A0C1K122_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">dld1</name>
        <name evidence="16" type="ORF">DB41_GA00050</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384434.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76481">
        <property type="protein sequence ID" value="KIC76481"/>
        <property type="gene ID" value="DB41_GA00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.807"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="4"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="346"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="180"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="317"/>
            <end position="320"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KIC76481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="463" mass="50243" checksum="49E48C386E10723C" modified="2015-04-01" version="1">MKQFDVVVIGAGPGGYVAAIRAAQLGMKVACIEKAQTLGGTCLNVGCIPSKTLLQSTRYWEWLEKESKGLGIEYNEIKVNFETMMQRKAKVVFSLTEGITGLFKKNKVESIRGTAKFVDSHLVEVTDNGRIEKIKGNYFILATGSEAVALPFLAFDEKKIISSTGALSLEKVPKQMAVIGAGAIGVEMASIYRRLGTQVHIIERAEEICLAMDPTIRKLLLRGLKQQGIKFHLSAHLHSAKYEREGVTIEFEEGGERKNLHTDLLLVAVGRKPHTEGLGLEQIGIKKSSRGTLNIDNFFRTSLPHIFAIGDIVDGPMLAHKASDEGMAVAESIAGKAAYVNYMALPQVVYTHPEAAAVGLNEPEAREAGLEVMVGTAFFKGNARARCMGESEGIVKIIGDKKSERVVGLHILGSHASEMIEEGALALQKKVTLEDIARLPHSHPTLTEAIKEAAMDALGYAMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K157</accession>
    <name>A0A0C1K157_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrom_C_asm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_FX00100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243858.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76501">
        <property type="protein sequence ID" value="KIC76501"/>
        <property type="gene ID" value="DB41_FX00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.790"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="529"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="611"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="634"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="674"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="6">
        <location>
            <begin position="463"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="706" mass="82072" checksum="C48C302C2E754B76" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K165</accession>
    <name>A0A0C1K165_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EC00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76870">
        <property type="protein sequence ID" value="KIC76870"/>
        <property type="gene ID" value="DB41_EC00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4956" checksum="C186AC0C131D6BC3" modified="2015-04-01" version="1">MWPFCPARQEGLRSNPFNFFCLLLVYTLLSNSLYILLVKSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1L0</accession>
    <name>A0A0C1K1L0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383575.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76970">
        <property type="protein sequence ID" value="KIC76970"/>
        <property type="gene ID" value="DB41_DP00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7067" checksum="B23107F6BAD3CAE8" modified="2015-04-01" version="1">MIHATHLYGEKNLNSALVTLQPLRGGCKVEVLESGKQGRVLKIRTPDHLIGFISQESIRFLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1M8</accession>
    <name>A0A0C1K1M8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243839.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76596">
        <property type="protein sequence ID" value="KIC76596"/>
        <property type="gene ID" value="DB41_FI00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.679"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="272" mass="31489" checksum="0FDBB15632762A61" modified="2015-04-01" version="1">MEKLKKNLDESIYSRLKNVAKQRKRPVQEILKYYAIERFLFRLSVSSHQNSFYLKGGLMLMVWNPMNHRPTVDIDLLAKTSNTISHLQKIIQEICSTEVIPDGLLFAVESLRLSEAQLEAEYHGISASFSAKLFTAKLPMRIDFGFSDTILPQPAIIKYPTLLDLPAPTLKGYTPQTSIAEKFESIIRLGFANTRMKDFYDIWLLIQQFDFDRDELQVIIQQIIKNRGTIVKSSPIAFEETFYNHSLKQDQWKAFLKDISHGVIFLEHVMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1U9</accession>
    <name>A0A0C1K1U9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FC00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000065">
        <property type="protein sequence ID" value="KIC76656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76656">
        <property type="protein sequence ID" value="KIC76656"/>
        <property type="gene ID" value="DB41_FC00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="9133" checksum="E63F4C5852483FBB" modified="2015-04-01" version="1" fragment="single">SMQLKVVCNLCLNHRLLGAFPNLLYSIFNPRLACQSSWRTIIRIAFTHYAPPFFEFAFILSKRGVWGHLLRDDRKLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2E1</accession>
    <name>A0A0C1K2E1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EG00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76836">
        <property type="protein sequence ID" value="KIC76836"/>
        <property type="gene ID" value="DB41_EG00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="16344" checksum="667D05BCAD754507" modified="2015-04-01" version="1">MNEDKQWDGFYGIQISKQSMKKEESLSSYHRLRKMEESFRVMKHSLEIRSIYLSSPEKVRGHIVLCFLAFVMHRNLEITLIRKGTDHTAEKIREAIGELEASLLEVNGKPILLRTPAKGLSKEILQSLKLKHPGEMVIDGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2E8</accession>
    <name>A0A0C1K2E8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CU00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000011">
        <property type="protein sequence ID" value="KIC77180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77180">
        <property type="protein sequence ID" value="KIC77180"/>
        <property type="gene ID" value="DB41_CU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="117" mass="13760" checksum="2577B0A263A84ADE" modified="2015-04-01" version="1" fragment="single">MPSLYKQIGKVHVPQGNIKEQSLILEKIYKLEEELSETAKVDAIFKQTFALASSLSPLELEFKWITEEKRYFTLANYSSYLVNINRLLMWNQIPGGKKFLDREEIKYLPLEKKESFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2R8</accession>
    <name>A0A0C1K2R8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Protein translocase subunit SecA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">secA</name>
        <name evidence="13" type="ORF">DB41_DN00220</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383510.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77001">
        <property type="protein sequence ID" value="KIC77001"/>
        <property type="gene ID" value="DB41_DN00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.313"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="12">
        <location>
            <begin position="375"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="461"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="797"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1169" mass="134610" checksum="5620560BAC408C45" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K379</accession>
    <name>A0A0C1K379_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CS00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383209.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77196">
        <property type="protein sequence ID" value="KIC77196"/>
        <property type="gene ID" value="DB41_CS00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="724" mass="81235" checksum="CAF69FEE7B792F58" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K394</accession>
    <name>A0A0C1K394_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CP00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243742.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77226">
        <property type="protein sequence ID" value="KIC77226"/>
        <property type="gene ID" value="DB41_CP00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.87"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="110" mass="12478" checksum="1A73355A71D529B9" modified="2015-04-01" version="1">MKEHCAQLNRLSLSHLNFIFLPPAIGQLSQLQRLYLHNNQLTSLPETIGQLSQLQQLYLDNNQLTSLPEATAQLSQLKKLNLSNNRLTTIPQLLTGVEILMRRNPLPTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K396</accession>
    <name>A0A0C1K396_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CP00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
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            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77231">
        <property type="protein sequence ID" value="KIC77231"/>
        <property type="gene ID" value="DB41_CP00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="10075" checksum="6C342C4596FB6901" modified="2015-04-01" version="1">MKTKSSAGIFFLLKEDQVKGINLLSSLISYRDYTFPIGFEVIKKDMHFCDVKTKKKGSHPLLKAHILEHFCNRQLCLSVKFENGLANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3D0</accession>
    <name>A0A0C1K3D0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CJ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77291">
        <property type="protein sequence ID" value="KIC77291"/>
        <property type="gene ID" value="DB41_CJ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="10533" checksum="C17F936B0123A646" modified="2015-04-01" version="1">MFDHCFLFHLSQTNFIKNKLPLATLGSLVEKSRVDALCQVIREIVEHENSKELFRDFEKTLDEIFVLRPSRKHLNAVQENVTFESSRKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3D2</accession>
    <name>A0A0C1K3D2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histone H1-like protein HC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hctA</name>
        <name evidence="6" type="ORF">DB41_CJ00060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Might have a role analogous to that of eukaryotic histone proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H1/H5 family. HCT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383022.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77296">
        <property type="protein sequence ID" value="KIC77296"/>
        <property type="gene ID" value="DB41_CJ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.6"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010886">
        <property type="entry name" value="Hc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07432">
        <property type="entry name" value="Hc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="13660" checksum="489440AF2ED2BB36" modified="2015-04-01" version="1">MALKDTVKNLRDLLQNITNDLEKAEKGNKAASQRVRTGTVKLEKVSKLYRKESIKSEKTTKGTKKTAKKVTAPKKASKPAAKPIATKPAAKPAAKPKAKAHKAKARPLSLKRPTAKLPTKQVGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3J8</accession>
    <name>A0A0C1K3J8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IX00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000155">
        <property type="protein sequence ID" value="KIC73877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73877">
        <property type="protein sequence ID" value="KIC73877"/>
        <property type="gene ID" value="DB41_IX00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="276" mass="32161" checksum="A8D0E3E8998FECB5" modified="2015-04-01" version="1" fragment="single">MVNSMTPLSLIPHIRIPEEVQLKILSFLDEKDLPIAALVNKHWQRMAQDPSLWRPICQRRWKNLSHSSSPGKNWRKICKKRVQMSQTMRLTKGEYSKNECKETIYKLPYFSGKILALKREKQFAFIKATAGTAQIYHLGEKSCQLVYDNVKEESSRLIHYQEGHIIQVTQEGQLYRWKVNEAFPQASLCYLGNFENAYWAQNHLFLVNPHQTQFKIVDVRTGLSYHKNTCAPINFILCRNNQALIHCLDGSLYFINDIENSFSMDLMVLEGILKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K668</accession>
    <name>A0A0C1K668_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IF00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74757">
        <property type="protein sequence ID" value="KIC74757"/>
        <property type="gene ID" value="DB41_IF00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4750" checksum="1668ECF365938408" modified="2015-04-01" version="1">MTAYKKEGFLPLPATKKVFLNILLSGSGVYRFKKSYKAIVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6V0</accession>
    <name>A0A0C1K6V0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pcrA</name>
        <name evidence="9" type="ORF">DB41_IB00950</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385791.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74962">
        <property type="protein sequence ID" value="KIC74962"/>
        <property type="gene ID" value="DB41_IB00950"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1529"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="3"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="281"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="668" mass="77418" checksum="42214F423F6E93B4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6W7</accession>
    <name>A0A0C1K6W7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplL</name>
        <name evidence="7" type="ORF">DB41_HY00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74977">
        <property type="protein sequence ID" value="KIC74977"/>
        <property type="gene ID" value="DB41_HY00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1398"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="58"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="127" mass="13222" checksum="05F99BCD83C61C14" modified="2015-04-01" version="1">MSKKTEDLVNTLSELSVLEMSELKTMLEDKWGVKAAAAAVAVAAPAAAAPAAPEATDFQVTLVESPADKKIGVIKVVREITGLGLKEAKELVDGAPKVVKETAPKAEAEDIKKKLETAGAKVTLKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K984</accession>
    <name>A0A0C1K984_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="2">dTTPase/UTPase</shortName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="2">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HH00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385206.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75717">
        <property type="protein sequence ID" value="KIC75717"/>
        <property type="gene ID" value="DB41_HH00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1207"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036221">
        <property type="term" value="F:UTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="194" mass="22372" checksum="EC15574544257595" modified="2015-04-01" version="1">MVRLILASQSARRKEILSYFNLPFKQVSPSFDEHSVIYKRDPIKYVSLIAEGKAKAVKDIGNHEAILAADTIVYRSGKIYHKPQTEQEAFSMLWDLAGKWHSVFTGVVLLYKANLYTGWEETRVLFNHLTKEDIYRYHQKIHWADKAGGYAIQRAGSLIVNKIDGCYYNVMGLPLNTLRSLLKNCEIDLWDYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9B1</accession>
    <name>A0A0C1K9B1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">A_deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HG00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385145.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75747">
        <property type="protein sequence ID" value="KIC75747"/>
        <property type="gene ID" value="DB41_HG00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="413"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="707" mass="81879" checksum="6BE70E646AF444AF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAK3</accession>
    <name>A0A0C1KAK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GM00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000098">
        <property type="protein sequence ID" value="KIC76127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76127">
        <property type="protein sequence ID" value="KIC76127"/>
        <property type="gene ID" value="DB41_GM00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5139" checksum="83B86CAB61657C6F" modified="2015-04-01" version="1">MAVEEGSKILFLKVRDWGAIRESYKHEGRPSPFHYSADLIKASMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAV9</accession>
    <name>A0A0C1KAV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative o-succinylbenzoate-CoA ligase, menE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">menE</name>
        <name evidence="2" type="ORF">DB41_GL00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384732.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76267">
        <property type="protein sequence ID" value="KIC76267"/>
        <property type="gene ID" value="DB41_GL00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.941"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="45"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="372" mass="41212" checksum="2E760596B1B617BA" modified="2015-04-01" version="1">MIKINWQSAESHLLLNPRLPVIKPSLWETGKMLINKFERHIWLNTSGSSQQKMVALSKDALLASAQAVNHHLQATSMDIWINPLPLFHVGGLAIQARGYLSGAAVSTFAAKWSVRHFYEMLLAKKGTLTALVPTQVYDLVVNKLPAPKSLRAVIVGGGALQGSLYTQARELGWPLLPSYGLTECSSQVATASLHSLSTSQFPPLEILPHVQVKTNEKGCFCLSSPALLTAYASFKAEEWQLIYPVAEGWLVTEDVGTLHHNLLKLKGRKGDFIKIGGENVEVGRLEEILEGIKLEQGIHTDMVLGAIPDERLGYAIHLFSTTPLVQSVQTLYDQRVLPFERIRKVHILQIIPRSPLKKLLRGELIRLASQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB86</accession>
    <name>A0A0C1KB86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GG00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76407">
        <property type="protein sequence ID" value="KIC76407"/>
        <property type="gene ID" value="DB41_GG00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5149" checksum="C328A64B24DC08C3" modified="2015-04-01" version="1">MLKQALPVKRNSLAVNPIKRFLINELEEGMGRSLIVGPLSLTPKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBD0</accession>
    <name>A0A0C1KBD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384545.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76462">
        <property type="protein sequence ID" value="KIC76462"/>
        <property type="gene ID" value="DB41_GC00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="374"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="756" mass="86027" checksum="5ED8D8E8F7D3F027" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC75</accession>
    <name>A0A0C1KC75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Quaternary ammonium compound-resistance protein QacF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">qacF</name>
        <name evidence="6" type="ORF">DB41_EY00180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383991.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76707">
        <property type="protein sequence ID" value="KIC76707"/>
        <property type="gene ID" value="DB41_EY00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.595"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="110" mass="11666" checksum="17BBE22C57FBF197" modified="2015-04-01" version="1">MEAYLYLLMAIAGEVVGTSALKASYGMTKLFPSLVVLVGYGLTFWSLSIALKTLPVGVVYAIWSGLGIVSIILIGVYFFNEAFSLMHLLGTALILAGVAVLMLFTGPVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCK9</accession>
    <name>A0A0C1KCK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="8">ALP N-acyltransferase</shortName>
            <ecNumber evidence="8">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">lnt</name>
        <name evidence="10" type="ORF">DB41_EH00010</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383777.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76817">
        <property type="protein sequence ID" value="KIC76817"/>
        <property type="gene ID" value="DB41_EH00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.468"/>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="529"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="217"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="554" mass="63087" checksum="0D4B1BA4F9E21261" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD08</accession>
    <name>A0A0C1KD08_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Act-Frag_cataly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DQ00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76937">
        <property type="protein sequence ID" value="KIC76937"/>
        <property type="gene ID" value="DB41_DQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015275">
        <property type="entry name" value="Actin-fragmin_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09192">
        <property type="entry name" value="Act-Frag_cataly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Act-Frag_cataly" evidence="1">
        <location>
            <begin position="236"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="377" mass="43038" checksum="CD669C2BA121C960" modified="2015-04-01" version="1" fragment="single">MDDSSRSPFVRANLDTLSLEGWNTLVGQMLDSQQEAVKKDGRKYIYLKPRDNEIALGREKEVSSSFKKLTHEKIIRIFISKLPPYLSEDQVIETQKNINRIFSTKETTILSKKFFSIFSSSSIGSKLPIEIAMNHRAVLGELARTLPETVQILRSTAGQTGIYFLHHTDYSEAPLALKLMPHPTTHLIADHFYRRLNFSTPLYTAFPRESELGQLALKKLEDLALNDLREKHDLAEDSQEAEIYGERIRQLEYQLESTQHIMVMKYVPGTTFAELPVDELMKALTQEKILLDIGAMIFLDVLLHNTDRMHPERSNNLDNLLLQPEASEEGRSIALIDHDFKVDSKNWTTVAKTLVKLAKGELTEKIIDNLCTSINIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD30</accession>
    <name>A0A0C1KD30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76952">
        <property type="protein sequence ID" value="KIC76952"/>
        <property type="gene ID" value="DB41_DP00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5850" checksum="37C865B35D93DD7A" modified="2015-04-01" version="1">MFIYFYVRAKFISLNLRGEIFSINKKLIDRLCQRKKHFFILFLSFFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDF0</accession>
    <name>A0A0C1KDF0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DL00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383476.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77032">
        <property type="protein sequence ID" value="KIC77032"/>
        <property type="gene ID" value="DB41_DL00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.278"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="196" mass="22904" checksum="0F5F001F4DBE449A" modified="2015-04-01" version="1">MANKIVIQTKRLILRSWIENDLEPFAQLNADERVMKYFPYRLNKEESDQMAKRMQAKIETEGWGCWAVSRLDTQKFIGFIGLNTVDKPTFPLHFAPCTEVGWRLAYESWGRGYATEGAEACLKYAFEILKLAEIVSFTAAQNCRSMAVMKKIGMHYHPAEDFNHPRISEGHWLRRHVLYRLKASEWQKMIIGKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1K1</accession>
    <name>A0A0C1H1K1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386900.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71574">
        <property type="protein sequence ID" value="KIC71574"/>
        <property type="gene ID" value="DB41_AV00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="306" mass="35763" checksum="D314EE3EF63D174A" modified="2015-04-01" version="1">MKVAPLTFPLQEASLRESYAQLLPSSLHSCLNGLDPFEIQSPVYGIGLVEQEQPVGIILATAHLQIHTAHIHSLNLDKHHANPRLARLLLEEMSRLLASLSTTLATFSYIQESPMASLLEKVFLEQKWQGPRPLIIECLFKRSDFNLQWWQSKNVTLAEGFEELLFKKITHKERQDLMHRQEQMSIPDYIFPLGREKNLIEYENSLALRYKQRIVGWMITHRTAPEVIRYSALYLEDDFSHTGYWLKLLIDALNIHSTMANAHYGLLEINLDQISKSWRKFIERRLFPQTSQISHHHSFWKDFNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2R2</accession>
    <name>A0A0C1H2R2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AE00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386644.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71929">
        <property type="protein sequence ID" value="KIC71929"/>
        <property type="gene ID" value="DB41_AE00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="267" mass="29452" checksum="B94D02AC3F6E02AA" modified="2015-04-01" version="1">MTPIKRSLLILALTLMWSPCFLLIKLALVDFNPATIVFLRVSLASLIFWIALRLQGGSLPKSFTFWKHSAFMAIFSSGLPSFLFCYAETSIESALAAILNGCSPMFTAILAHLFLPNDRMSIHKLIGILISFFGILLLFSPNIAQGMDGDFIGMSAALVGAFCYAISHVYAKKFIAGQARFVAPTAQLFMTALMMLPFVLGSLETKSSFTFPSLTSMLAILGLTLLGTYLAFFDLLLSFRALRSYSSINGFLFFSCGRYVIRLFISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3F6</accession>
    <name>A0A0C1H3F6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KV00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72089">
        <property type="protein sequence ID" value="KIC72089"/>
        <property type="gene ID" value="DB41_KV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="2">
        <location>
            <begin position="5"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="23969" checksum="0488008A20088EBE" modified="2015-04-01" version="1">MAACDEEFKEGIKYVAIDLWAPYRAVVEEMLPKAQAIADRFHVMQNLNQALDRFRKRVKQESADQEIWKNTKYILLKNHENLTKQQEDVLDKILNLNLELKVYYKLKESFRSLFNDLNDNRQTGSEKLSAWVLNTLRHKAIGYYEFIKTLLNWEDNILNYFDKRVSSGFAEGVNNKIKLIKRKAYGFINFENFRIKIIDSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H453</accession>
    <name>A0A0C1H453_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalt-zinc-cadmium resistance protein CzcB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">czcB</name>
        <name evidence="3" type="ORF">DB41_KO00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386445.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72324">
        <property type="protein sequence ID" value="KIC72324"/>
        <property type="gene ID" value="DB41_KO00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="53"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="378" mass="41863" checksum="472E3F3CFEBDE31A" modified="2015-04-01" version="1">MSKRIFLYIGLVFQQYLAASQEFKPELSNFVSLNNEQMIEAEIEILKASPSILRKTFGAPAQIVINEQQQAIIVARVSGVVSHISKNVGDYVSKGETLAVLQSRPMANFKAAYLTLLKRSSLAQQAFKAEAILKEKNVTSEQAYLQAFLTAEDACVKQELAEQQLYLLGMSKKDVKQLAQEESCDLFSYQIKSSLNGMVTSKIINLGSSLNAGQEAFKIADLDTVWVQIGVYAQDLPYLKLGDKVQVALLKEEKFSDLAEIIYLSPILDKQTRSGTAIALLANQSRKWYPGSYARVEVIAEEVEVPIAVLKEAIQVIEGKTVLFIAHSQGFEKREVKIGRSDPTYVEILSGIKQGTPYAATHTFILKAEDGKKAIKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H509</accession>
    <name>A0A0C1H509_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KI00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72569">
        <property type="protein sequence ID" value="KIC72569"/>
        <property type="gene ID" value="DB41_KI00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="6417" checksum="9AF6963545ECB4A0" modified="2015-04-01" version="1">MLKNISGEIWQHFHLWLKNFVFYYLLHLRKRQVLRFKEEAKPSLTIFLNLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H514</accession>
    <name>A0A0C1H514_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ankyrin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KI00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386350.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72574">
        <property type="protein sequence ID" value="KIC72574"/>
        <property type="gene ID" value="DB41_KI00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="105" mass="12706" checksum="F296E8788405554B" modified="2015-04-01" version="1">MFSPDILEEKLNINERKMRELAIRLEKLDEDTHAFLEELEISPEQLTTFISQKENFTDDNWQELQQQKKQMDDKLETELNNIRNPLQSKQIFSSLNVARHWLYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6Q5</accession>
    <name>A0A0C1H6Q5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Insertion element IS402 uncharacterized 16.2 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JR00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000174">
        <property type="protein sequence ID" value="KIC73129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73129">
        <property type="protein sequence ID" value="KIC73129"/>
        <property type="gene ID" value="DB41_JR00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1812"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15878" checksum="4B856BB08674DC74" modified="2015-04-01" version="1">MSNTYPSHLSDREWEAIKIYFEVDYSKGGRPIKHTKRELLEAIFYVLRTGCQWHYLPKDFPHWKTVYTYFKKWKDAHLFEKINHHLRKKLRVIMGRNLDPSAAIVDSQSVKTVERGGSQVMMVLKRLRGVKGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8H1</accession>
    <name>A0A0C1H8H1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Elongation factor P--(R)-beta-lysine ligase</fullName>
            <ecNumber evidence="3">6.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">epmA</name>
        <name evidence="3" type="ORF">DB41_JC00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000160">
        <property type="protein sequence ID" value="KIC73664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386111.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000160.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73664">
        <property type="protein sequence ID" value="KIC73664"/>
        <property type="gene ID" value="DB41_JC00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1719"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004525">
        <property type="entry name" value="EpmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00462">
        <property type="entry name" value="genX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="2">
        <location>
            <begin position="17"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="317" mass="36154" checksum="033CDCCF33CB2F72" modified="2015-04-01" version="1">MAAQLNRVKILRDRAYMLAQAREFFAKQQILEVDCPILTQGASVDANIDLIPARYANLEIRYMHSSPEYGMKRLLAEGMSDIYQLSHVFRDAEFSCKHNPEFMMAEWYRLGVSYEFMIAEALDFVRLFLGPLPAYTISYREALQEYANLDYVKASIPDLIEYLQNRGIQPYVQIEKEGKDALLNLILAMVVEPQLGKDKLCVLTDYPATQAALAQTKWQNDEQIAERFEIYYAGLELANGYHELGDVGEQRKRLMEANQIRDSLGKNQLPIDEAFLEALKKGFPDACGVAIGFDRLMMLRHQASTIAEVIPFAWATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9F7</accession>
    <name>A0A0C1H9F7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AX00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000219">
        <property type="protein sequence ID" value="KIC71503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71503">
        <property type="protein sequence ID" value="KIC71503"/>
        <property type="gene ID" value="DB41_AX00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="7574" checksum="991F85328700EE7F" modified="2015-04-01" version="1">MDVDGDLSEVTGVVVCVNLVHFAVVINPTVQIEEVYKNEESIPVASQSPSGILPCRKPLEANLHCGSQLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAD7</accession>
    <name>A0A0C1HAD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ATP-dependent transporter ycf16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ycf16</name>
        <name evidence="6" type="ORF">DB41_AI00050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386719.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71798">
        <property type="protein sequence ID" value="KIC71798"/>
        <property type="gene ID" value="DB41_AI00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2160"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC71798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="261" mass="28872" checksum="7386C6632A09EE36" modified="2015-04-01" version="1">MTHLPQALIEIKNLHANVENKPILKGLNLTVQAGEIHAIMGPNGAGKSTLAKILAGHPAYEITSGEILFKGQNIVELAPEERAHAGIFMSFQYPLEIPGVSNLQFLYASYNSVLKAKGSPEMPLVEFEKSLDEIMKRMEIKTEFKERSLNEGFSGGEKKRNEILQMAVLQPALAILDETDSGLDIDAMRIVARGVNQLMNPQMGLILITHYQRLLDYIKPNVVHVMVEGKIVQSGGPELAHQLEDKGYDWLVPAPQSEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAZ5</accession>
    <name>A0A0C1HAZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfbD</name>
        <name evidence="4" type="ORF">DB41_IJ00400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385953.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74569">
        <property type="protein sequence ID" value="KIC74569"/>
        <property type="gene ID" value="DB41_IJ00400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1620"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="3"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="286" mass="31751" checksum="B1BD228DE4F29AAD" modified="2015-04-01" version="1">MKKILILGKQGQVGWELCRTLSPLGQLITYDRKALDLASPLSIRELLRGLKPHMIVNAAAYTAVDKAEAEKEACMAINARAPQILAEEAKKLNALLVHYSSDYVFDGCSPSPSTEDTVPNPQNFYGYSKLEGDRAIQALGCAHLILRTSWVYGNRGHNFLLTMLKLGLEKDTLKIVDDQMGAPTWSRLIAEATAQVMARYEGQDGIYNLTCRGKTSWFGFAKAIFEGYSLKRGVKMPTLVNVPSSAYPVAAQRPHNSLLSHEKTEKTFGIQLPDWNETLQMCLEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB24</accession>
    <name>A0A0C1HB24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AC00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71988">
        <property type="protein sequence ID" value="KIC71988"/>
        <property type="gene ID" value="DB41_AC00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6454" checksum="239A61FC5436B208" modified="2015-04-01" version="1">MTLPLLPLVINKELQEIRFLKGELKEEKPLQDDFQSLKHHLIINGNGQILTFSAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBU0</accession>
    <name>A0A0C1HBU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74889">
        <property type="protein sequence ID" value="KIC74889"/>
        <property type="gene ID" value="DB41_IB00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="107" mass="12364" checksum="B727B1541D74F7E2" modified="2015-04-01" version="1">MRYIQYTVILRSRIAVETSPKVSLPAMTANRFVIHYPRGCRREVSALEINDKLDIYLKGLCPNPEDVELYLVMMEATFKAKEGDRELQLSKFKSQLTNHEASVPKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC01</accession>
    <name>A0A0C1HC01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Autotransporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IB00770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385762.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74944">
        <property type="protein sequence ID" value="KIC74944"/>
        <property type="gene ID" value="DB41_IB00770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0964">Secreted</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133795" description="Autotransporter domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="3">
        <location>
            <begin position="114"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="394" mass="44405" checksum="440E5AF4DFD1E978" modified="2015-04-01" version="1">MKNNLKTLLTLCLSSCTLICPLGNLMSASFSTSTYNERHVAQQWSSTSIVSADEALVIDNLSALSSKEQREALNDLSGEQYANLIQPNQTASQTFIRRMYQPIINDSLGLHCGENCDEYRAWGAVGGGQSRLRNSHGAKGYRMDNFNITFGAQKPLNLNFLNSWLTVGIAGSYEKDHIHFKQNGHGKGNNWQGAIYYMWNNPHFYSFSGTILGADCVRVKRSIDVGNLTRKAKGKARVSEWTSFTELGLNLGYENFYVQPFARLEHASYRRHALSEHGAQSLNLHVRGKNISASVGYLGTHLSTNLPWWELHLNADAAWKYRFNLLQERFQAHFKNLGSQFRIKGVHQKTSGFEGSVNIAKTFYNCWQGYVEFSGEVWDRFSAWNLAGGVTVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEG4</accession>
    <name>A0A0C1HEG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">mRNA interferase YafQ</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yafQ_3</name>
        <name evidence="2" type="ORF">DB41_HC00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000113">
        <property type="protein sequence ID" value="KIC75824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75824">
        <property type="protein sequence ID" value="KIC75824"/>
        <property type="gene ID" value="DB41_HC00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="5079" checksum="4E8B0F0AD9570445" modified="2015-04-01" version="1" fragment="single">RLVGNFKGRWECHIEPDWLLVYLKTDEDIIFERTGTHSDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFY2</accession>
    <name>A0A0C1HFY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243886.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76294">
        <property type="protein sequence ID" value="KIC76294"/>
        <property type="gene ID" value="DB41_GK00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="294" mass="34122" checksum="FF227AEA01AC4C28" modified="2015-04-01" version="1">MCRLKLLLLVFLCACTYKPQSENYRLFYHHLEQACPRKVCEEKSPYFLVILVEARHLDYSCPRSFFKTLAKHPSDGTKNGDVGHAWIYLQGVLEEDSQEKSSYVFLEGGHSGELGYMQPRYMEGVFLQAEQGEKNPIAYLWQTQHDGFFQHGPGRHYPTFAAKINLTASQFHLILKFIKNYSFSNYAIIGNQCCSFATQVAALAGLILESKISLKIDPFFHIGNHTICLWKDPLYSQITFFSPDVLERSLMQAVAEGRAEEALTWYKKKYPSPRRWKKEDFFLFPKRYLRLKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH80</accession>
    <name>A0A0C1HH80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipid II flippase FtsW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsW</name>
        <name evidence="7" type="ORF">DB41_FD00130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76654">
        <property type="protein sequence ID" value="KIC76654"/>
        <property type="gene ID" value="DB41_FD00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.654"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="393" mass="42925" checksum="6ED9A1D3B864D3F7" modified="2015-04-01" version="1">MRILPLMNAHKKVMGKKSTLSFPPIFCLLFLCVSIIYVLGLIMVYSTTSAEVMDMELNKSTHQALIKQLMYAGIGLSLAGGIAKIGYRTLITLSPWLLGIFSFLLFITLIPGIGREVNGSRRWLAILGLSLQPSEFVKYIIPAYFIHHYLKFSGKAFTFYAFLKLVGTIAIPMLLILVEPNNGTTAVIAMSVLVLCILMKISWRYWALPLLACLCVGGAFAYHLSYVSARLKVYLNPELDLKGKGHQPYQAKIAAGSGRLLGRGPGNSMQKLSYLPEAQNDYIAAIYAEEFGFIGVCILITLYLSIACLGFYIANASSSLEGFYFCAVITFLVTFQAFLNLGVVSGLLPSTGLNLPWFSQGGSSLVANILGLGIILNISQHVKGHLSDFSTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHC7</accession>
    <name>A0A0C1HHC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metallo-hydrolase YycJ</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yycJ</name>
        <name evidence="2" type="ORF">DB41_EY00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76709">
        <property type="protein sequence ID" value="KIC76709"/>
        <property type="gene ID" value="DB41_EY00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.597"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="15"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="260" mass="28684" checksum="8B62B2C7EA4425BB" modified="2015-04-01" version="1">MLQMIGFCPLASGSKGNCVYLGTPQLKLLIDAGLSARATKEKLAEIGVDFRELDAILITHEHSDHIQGLKVLALKMGIPVFANHETAKGIVEQLHECPKFKIFSTGESFEFGDLEIHPFNIQHDTLDPVAFTLKLDGLKLGFCTDLGFVSTLVLHQLQACDYLYVEANHQPSMVHASSRPMVYKQRVLSRNGHLSNEACAELLSKIAHPNLKHVYLAHLSSECNTPETALGVVKDKLQSYGITLEMCVAPQAMVSQPIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHK6</accession>
    <name>A0A0C1HHK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsH</name>
        <name evidence="7" type="ORF">DB41_EI00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383816.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76794">
        <property type="protein sequence ID" value="KIC76794"/>
        <property type="gene ID" value="DB41_EI00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.492"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15188" checksum="A956FC40046D1057" modified="2015-04-01" version="1">MAIPSDPVADFLTRIRNAAKAEHRYVDVSWSKLKENLAEILKLYGFIENYLVNKDQNHRGTIRLFLKYVEGRQPVIQGLKRVSKPGLRKYVGHEDIPHFYGGLGLSIVSTSQGLMAGNEARKRHIGGELLCLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI84</accession>
    <name>A0A0C1HI84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IQ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74298">
        <property type="protein sequence ID" value="KIC74298"/>
        <property type="gene ID" value="DB41_IQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="147"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="189"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="239"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="297"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="314"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="339"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="364"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="414"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="464"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="501" mass="56073" checksum="3B968DA040D4C3C9" modified="2015-04-01" version="1" fragment="single">MKLSGFPQLCIWIDRKADYVPLISTVTNLVNIFQKCVYIPTLQEKNLSVSKSYYRYLNKKSFGRCIVLLIPILGNIWVGVWDIHRYRLKNKNPKPLRADQTINSPQDAVKEINNESAPLVIVQKGELTLDNLSEEFKKDKATALAEMQKNGWELSQAREDFKKDQDIVLAAVKQSGLVLKYAHPELQNNKNIVLAAVSQDGLALKYASQELRNDKEVVLAAVQQDSLGLEYASQELKNNKEVVLAAVKQNGASLKYASQALKNDREVVLAAIHHQDPALQYLDKTVIDNERFVLVDFKHPCLTIQYGGKKIKNDEEVMLAAVQQDGLALKYASEEIKDNRKVVLAAIQQNVWALEYASRSLRDDKYLLLIAVRQAGSLLFYASPWIKSNKDIVLAAVQQDGLALRHAGEDLKNDKEVVLAAVQQNGQALQYASQELRNDKDIVLAAVQQDVRALEYAGEDLNNDKEVVLAAVQQNGKALQYASQALKNDKDIVLAAVRQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI99</accession>
    <name>A0A0C1HI99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383523.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77009">
        <property type="protein sequence ID" value="KIC77009"/>
        <property type="gene ID" value="DB41_DN00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="212" mass="25074" checksum="6FD50EBF9085013F" modified="2015-04-01" version="1">MSKKMRRASDLSHEAKWGKLTPEEIAYVEQKLQDKEADEDEDLDTWIFIVGRLGLTRHRPLLEKFLYYQTEPWVCMQALKALCTYWEYTKDYLKELKMFIRGVEWDPHDDIRLWALSIAGDFLKENDDPELLQLVLDVFENLEKLNSFHEHSTYAREFIRSCAFNALAIASGKKYQDLTDTDDIENCLLNGQMELLDLSVLKKARQRLQQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJE9</accession>
    <name>A0A0C1HJE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_II00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74623">
        <property type="protein sequence ID" value="KIC74623"/>
        <property type="gene ID" value="DB41_II00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7394" checksum="6690E24A14E554F3" modified="2015-04-01" version="1">MQTASKPPFFVRFLYALCPKNGELGGLILWKFCLEGVCKKFLITKNETKFWKKYQAKKYKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKE4</accession>
    <name>A0A0C1HKE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="9" type="ORF">DB41_IB00860</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385775.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74953">
        <property type="protein sequence ID" value="KIC74953"/>
        <property type="gene ID" value="DB41_IB00860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1521"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="8">
        <location>
            <begin position="104"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="187" mass="21100" checksum="2C3EA8F98AB09511" modified="2015-04-01" version="1">MKLNVTKRTAGKKSSSKQLRRAGQVPAIIYKRGNEQADNIALNISEFNALGRQVQPGRLSTNVFTLVDENGQERRALLKEIQYHVTRYDVLHLDFEELVDDVQVNVKVPIECTGVVDCVGIKLGGVLRQVIRYLKVRCLPKDIPSAFVLDIKNMNQRETRRLADLNIPESIRPLADLNEVAVAIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLT7</accession>
    <name>A0A0C1HLT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphorylated carbohydrates phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HO00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75363">
        <property type="protein sequence ID" value="KIC75363"/>
        <property type="gene ID" value="DB41_HO00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="229" mass="25797" checksum="B8B78958C7D7B25F" modified="2015-04-01" version="1">MGRLGMSLSMDFQHLKGVLIDFDGTLVDTIPFLFKHYLSFLKTFGQEGSLEEFKTLMGPSLEEFVPILIERYRLPEKKHALISLYHHGLADVYKREGKLIPGAREFLDFCQHKKIKMGLVTSSAYPLIASCVEALEIKDYFAFIVTKENVKKTKPDPEIYLHALKTSSLLADQVLAIEDSRAGILAALNAHIPTIAIRNPYLISIPSGAMTTDSWKDLTLCFEEAYARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN83</accession>
    <name>A0A0C1HN83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HE00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385071.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75788">
        <property type="protein sequence ID" value="KIC75788"/>
        <property type="gene ID" value="DB41_HE00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="250" mass="28630" checksum="49D69396705053F0" modified="2015-04-01" version="1">MKINTQDLFNDINALRLYEVAVSISRENGKKSYTIKRVKLNQHDSIERIEALITKLNEGKIWLKVGKRREGTVKYVGKGLKPSEIASIILKKQDKTDITPIEISIDITKENLEDQVEEMSHQDISLLERIAKSLQTTFKLDIQKKVNSQAHIINHHVANSSVKSKHASAAKATMPEERKVTYRSRSQESKKEKKVEEEKAIEKQRGQKRKALTLAKELDEKSDKRRLRAVKSTEKQKEILKAVPSPRKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNK1</accession>
    <name>A0A0C1HNK1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TyeA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384997.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75878">
        <property type="protein sequence ID" value="KIC75878"/>
        <property type="gene ID" value="DB41_GZ00420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015144">
        <property type="entry name" value="T3SS_TyeA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013351">
        <property type="entry name" value="T3SS_TyeA-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038347">
        <property type="entry name" value="TyeA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09059">
        <property type="entry name" value="TyeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02511">
        <property type="entry name" value="type_III_tyeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TyeA" evidence="1">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="106" mass="12289" checksum="DCFE16774274D3EF" modified="2015-04-01" version="1">MAKFTAHEVSRQFLYLAAERFLSSDKIIQAAVKAGAQTIEDKITLINQMRDAVRQVSIHHIFRSVQHRDEMFSAILEALSDLEDQLEEELIKQEEEQQLHINPNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQJ3</accession>
    <name>A0A0C1HQJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384524.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76453">
        <property type="protein sequence ID" value="KIC76453"/>
        <property type="gene ID" value="DB41_GC00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="35"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="29454" checksum="756DAA2C78567DEC" modified="2015-04-01" version="1">MERVEEKEAIVLEVEGYKLFGVLHLPLKGEKVPGILMCHGLAGNKIGRFRTAVTLAKELAKRGIASLRIDFRGCGDSDGDFCEASVKGLLKDAGASLNYLQKHARIDPYRLGVLGRSFGAAIALMAAHSHKNIKSLALWAPLYNTEQWQEAWRIFHDVHTPAKVREQLLSIEGQQGSPIFFEEFFNVDLAPTLEALADVPLLHIHGLKDSVVKVDHANLYENKRSTARATSKFIKIPKGDHHFTHKNDQELVIAETVNWFKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRE1</accession>
    <name>A0A0C1HRE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YusI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yusI</name>
        <name evidence="2" type="ORF">DB41_EY00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383971.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76693">
        <property type="protein sequence ID" value="KIC76693"/>
        <property type="gene ID" value="DB41_EY00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006504">
        <property type="entry name" value="Tscrpt_reg_Spx/MgsR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01617">
        <property type="entry name" value="arsC_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="119" mass="13587" checksum="0844B217A0A613C6" modified="2015-04-01" version="1">MSVLVYLHTKCSTCQKALQFLDKANISYTAIDIVKSPPSLEELNKMLSYYKGDTKKLFNSSGRLYKELQLSQKLPYMSQNEALSLLHAQGMLVKRPFLLGDDIGLVGFREEHWQPVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRH6</accession>
    <name>A0A0C1HRH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UPF0750 membrane protein YqfU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">yqfU</name>
        <name evidence="9" type="ORF">DB41_ET00030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383938.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76733">
        <property type="protein sequence ID" value="KIC76733"/>
        <property type="gene ID" value="DB41_ET00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.555"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006483">
        <property type="entry name" value="Membrane_protein_YitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="233"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="310" mass="34185" checksum="26D8F705AFC1B6C7" modified="2015-04-01" version="1">MHHPTSASAKSIGSELIIYLFLITGAFLAAFAIQVFLIPNRLIDGGIVGIAMVCANIFGTQYLGYFTFALNLPFVFLAYRYIGKVFVLHMFFALLFFTGFIFFIEHYMPWAEFKGETLEVVVIGGALLGIGIGLIIRYGGCLDGTEILGIISNRLTGFTVGQVVLVINIFVFSAAGIAFKDWHPPLLSLITYMVVSKIMDTVIVGLDETKSVIIISSKSEIIANAIVHELGLGLTIMYGRGGFSGDEREILYVIAERLQLADLKELIYREDPAAFIAIENLHEVANGNQTGKYKKTSLKELFSRMLSIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRQ6</accession>
    <name>A0A0C1HRQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gap</name>
        <name evidence="10" type="ORF">DB41_EI00230</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383833.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76808">
        <property type="protein sequence ID" value="KIC76808"/>
        <property type="gene ID" value="DB41_EI00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.507"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="PTHR10836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="212"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="36637" checksum="B4A691F73BB7C1C4" modified="2015-04-01" version="1">MSLKIAINGFGRIGRLVFRLISERNDMQVVAINDVVSPSNLAYLLKYDTVHGKFKGEIKEEGEYLLFNGKKIRVIAEKDPQKLPWKDLQVDYVLESTGLFTSFDEAGKHLKSGAKRVLISAPAKGEGIATIVLGVNEEKYNPANDKIVSNASCTTNCLAPITKVLLENFGIEEGLMTTVHAMTATQPTVDGPSHKDLRGGRAASQNIIPSSTGAAKAVALCLPQVKGKLTGMALRVPVVDVSIVDLTVRLSKPTSYESICQEMQKASEGYMKGILGYCDEPVVSSDFIGSRYSSIFDKDAGIALNDTFYKIVAWYDNEMGYACRCVELLAYMASKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRW4</accession>
    <name>A0A0C1HRW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76858">
        <property type="protein sequence ID" value="KIC76858"/>
        <property type="gene ID" value="DB41_EC00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7232" checksum="47B84A65E4ADB72D" modified="2015-04-01" version="1">MTKAELIKKIAVLESVNDQMYSELCEVDRLMRLVGFEGGLETVKLTAQELYQSEHIGEEGEEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRY5</accession>
    <name>A0A0C1HRY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EB00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000041">
        <property type="protein sequence ID" value="KIC76878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76878">
        <property type="protein sequence ID" value="KIC76878"/>
        <property type="gene ID" value="DB41_EB00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5478" checksum="0559732F1F418095" modified="2015-04-01" version="1">MKLDLFDIYTDYLISHNQQAIATALSKLLDGQISHDKITRFLNNNRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSD5</accession>
    <name>A0A0C1HSD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76993">
        <property type="protein sequence ID" value="KIC76993"/>
        <property type="gene ID" value="DB41_DN00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5310" checksum="6A900523A58C5444" modified="2015-04-01" version="1">MLILINQGDHNDIPTLYSKNLRKPNFLIDKFLTNGLNKKTLQGIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSP2</accession>
    <name>A0A0C1HSP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DH00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77068">
        <property type="protein sequence ID" value="KIC77068"/>
        <property type="gene ID" value="DB41_DH00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133294" evidence="1">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8330" checksum="35782E3DCB10D4DC" modified="2015-04-01" version="1">MKQIATKIIFSFFILTTVFADAVENSVIPAMERFGCIENLPSQKFTKQQFSEIDNALEKRRNDQTCYLQCAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJS3</accession>
    <name>A0A0C1JJS3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoenolpyruvate carboxykinase [GTP]</fullName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="8">4.1.1.32</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GTP-dependent phosphoenolpyruvate carboxykinase</fullName>
            <shortName evidence="8">GTP-PEPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">pckG</name>
        <name evidence="11" type="ORF">DB41_AV00200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10388"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.32" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386916.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71580">
        <property type="protein sequence ID" value="KIC71580"/>
        <property type="gene ID" value="DB41_AV00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2256"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004613">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00819">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00452">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018091">
        <property type="entry name" value="PEP_carboxykin_GTP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008209">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035077">
        <property type="entry name" value="PEP_carboxykinase_GTP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035078">
        <property type="entry name" value="PEP_carboxykinase_GTP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11561">
        <property type="entry name" value="PTHR11561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00821">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17297">
        <property type="entry name" value="PEPCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001348">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00505">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEPCK_N" evidence="10">
        <location>
            <begin position="10"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="PEPCK_GTP" evidence="9">
        <location>
            <begin position="235"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="210"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="376"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="262"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="504"/>
            <end position="507"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC71580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="595" mass="67054" checksum="769F2A90539B67AE" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKY8</accession>
    <name>A0A0C1JKY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_3</name>
        <name evidence="3" type="ORF">DB41_AE00250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71950">
        <property type="protein sequence ID" value="KIC71950"/>
        <property type="gene ID" value="DB41_AE00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2142"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="392" mass="44843" checksum="011EA029777D9E56" modified="2015-04-01" version="1">MKWLYLDDNRFTTFPIEIRHLSQMQKLDLSYNQLTTLPAEIGQLSQLKELYLNDNHLTALPTEIGQFSQLKALNLSDNQLTSVPAGIGQLSQLQSLCLDHNHLTSLPAELGQLSQLRDLNLGNNQLAFLLIEIGQLLQLRWLYLNNNQLTSVPAEIRQLSQLRRLYLKNNHLTSLPTEIWLLSQLEWLGLENNQLTFVPDEIKQLSQLQSLRLGDNHLVTLPAGTWQLSKLQQLHLNNNQLTSLPAEIGQLSQLHYLNLKNNQLTTVPAEIWLLSRLKWLDLENNQLTFIPAEIEQLSQLQILHLGDNHLATLPVEIGQLSQLEKLHLNNNYLTVLPAEMGQLSRLQELDLCDNQLASLPAAIEQLPKRLNLRLDGNPLKNIPNELKKRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL83</accession>
    <name>A0A0C1JL83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72045">
        <property type="protein sequence ID" value="KIC72045"/>
        <property type="gene ID" value="DB41_AA00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="10924" checksum="BED06A4F3A91EE71" modified="2015-04-01" version="1">MLPILYCQIALPSSLLRRYRPYKYLNYKERFYSLRLLVFLKDKGTDQKFEVVRLIKKRGGEYMVQKKSYFIFKLCSCRKLLCFSLLCSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLH3</accession>
    <name>A0A0C1JLH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Geranylgeranyl pyrophosphate synthase 4</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
            <ecNumber evidence="3">2.5.1.1</ecNumber>
            <ecNumber evidence="3">2.5.1.10</ecNumber>
            <ecNumber evidence="3">2.5.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ggpP4</name>
        <name evidence="3" type="ORF">DB41_KU00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EC" id="2.5.1.1" evidence="3"/>
    <dbReference type="EC" id="2.5.1.10" evidence="3"/>
    <dbReference type="EC" id="2.5.1.29" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244074.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72110">
        <property type="protein sequence ID" value="KIC72110"/>
        <property type="gene ID" value="DB41_KU00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2052"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:geranyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="299" mass="32757" checksum="F894D007D7ED7A9E" modified="2015-04-01" version="1">MIKNDPFSYILAPYQLAFESSLRQAIALLGPKTNLRDVCEYALMNGGKRFRPFLVLVIAKALKAPVDVSFAALAVEFFHTASLLADDLPCMDNDDVRRDKPSAHKVYGESLALLASYALIASGYEFLAKNAKVLSLSGALHAAQSDRICLLALENCTFNTGLLGATGGQFLDIYPPDLSINTLKEIIRMKTGSLFEISFVLGWLYGGGALDKLADIKKAAYHFGMAFQIADDFGDVEQDAHQGKLVNLVAKCGREDAFKMFLEEIEAFKVISQQLNLDVPELSTLCDLLTSQINSEKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLP5</accession>
    <name>A0A0C1JLP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KR00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386522.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72190">
        <property type="protein sequence ID" value="KIC72190"/>
        <property type="gene ID" value="DB41_KR00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2043"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="24061" checksum="2A32CFCC53E03F02" modified="2015-04-01" version="1">MLETIPRKRLLFYGLCIGLLPLIFVALHFYSQLEKLNHLKETIHCTHDTAIMREKKQATNMAVIQHFREADHHYIDKYLETLVFLETEIESLQKLENNKNFAFDDDLKKRLEYLANNNSLAFTEGVVQSYPLFQETTETLVHPVEVDVEDIQKILSRIEAIPIGPYAPPSHPPQLLILDFKINRKNISENNEAFSLDLKLLKREFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLU5</accession>
    <name>A0A0C1JLU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KQ00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386482.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72245">
        <property type="protein sequence ID" value="KIC72245"/>
        <property type="gene ID" value="DB41_KQ00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="157" mass="18337" checksum="DDB69BF26E40040A" modified="2015-04-01" version="1">MKYLFILFTTLSLSLAAEESVIDFFEKRLSLQPPTEQEELAVVQAIQIFLERIQQRNINDAYFLSTSKEFQKASSFNYFRLFTQDLYGKVLTTQLTRNNVSFTNVVKDQATYQILLKGSPAHQKFYLEFDLANQEGDWKIMHIKIYESYSSNSSQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM69</accession>
    <name>A0A0C1JM69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AU00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71621">
        <property type="protein sequence ID" value="KIC71621"/>
        <property type="gene ID" value="DB41_AU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="82" mass="9724" checksum="250D3B0EDEE222EA" modified="2015-04-01" version="1">MRIISHKALKAAIKSLCEPLVSSLLLETPCDYIKLNSKSRYKELRNQQNLFHHLIVEKRAFLNKQDFDIVNEIIRIMFRPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM82</accession>
    <name>A0A0C1JM82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AT00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000216">
        <property type="protein sequence ID" value="KIC71641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71641">
        <property type="protein sequence ID" value="KIC71641"/>
        <property type="gene ID" value="DB41_AT00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4694" checksum="E2FADA355EFDAF9D" modified="2015-04-01" version="1" fragment="single">MPGRFEGLTDTQWRILQPLLPQNPPKNLKGKPHTPWRKIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMZ6</accession>
    <name>A0A0C1JMZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71946">
        <property type="protein sequence ID" value="KIC71946"/>
        <property type="gene ID" value="DB41_AE00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5401" checksum="FB915D024678F275" modified="2015-04-01" version="1">MIFLIGSIVKLFAIVQLICTIKIKALCPQLGAPKIFPGNLSFIICVNPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNL7</accession>
    <name>A0A0C1JNL7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_Tnp_IS630 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KU00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72106">
        <property type="protein sequence ID" value="KIC72106"/>
        <property type="gene ID" value="DB41_KU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002622">
        <property type="entry name" value="Transposase_14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01710">
        <property type="entry name" value="HTH_Tnp_IS630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_IS630" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="13855" checksum="75D876F691FEF743" modified="2015-04-01" version="1">MVYSHDLRKKALNYIKNGGSMATASVVFGVTVRTLTNWIKRKKQGDLAPKKRRPSPSKIDSEKLKLYIKQTPDAYLREIAEGFGVTIAAVFYACKRLKITLKKRHPSTRKEMSISERNLGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNM0</accession>
    <name>A0A0C1JNM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acetyltransferase YaiX</fullName>
            <ecNumber evidence="1">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yaiX</name>
        <name evidence="1" type="ORF">DB41_KU00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386537.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72111">
        <property type="protein sequence ID" value="KIC72111"/>
        <property type="gene ID" value="DB41_KU00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2053"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="227" mass="24475" checksum="D7ABBEEED7221772" modified="2015-04-01" version="1">MNNFSPDYFFDLTTFAHAKLFKSCTFVWNALSLIPSYLKTLALGEIEAPVPQGTYLVNPHLISIGQGTIIEPGAYIKGPCIIGQNCSVRHGAYIRGNFIAGNECVIGHATEVKNAIMFDKAQAGHFAYLGDTILGSRVNLGAGTKCANLRLNRQNVSIYLDGSFIETNLKKFGAIIGDDSQIGCNSVTNPGTLWGKKVICYPCVNAGGYIASHQLIRSSQKAIITPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP62</accession>
    <name>A0A0C1JP62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ferrochelatase</fullName>
            <ecNumber evidence="6">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">hemH</name>
        <name evidence="8" type="ORF">DB41_KO00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386441.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72321">
        <property type="protein sequence ID" value="KIC72321"/>
        <property type="gene ID" value="DB41_KO00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1988"/>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="343" mass="39204" checksum="1FDA58407D2571A9" modified="2015-04-01" version="1">MYHSPIGILLVNLGTPDSPQPKDVYKYLVEFLTDERVIDLPWLQRQLLVRGIIIPARYKQSARSYQNIWTAEGSPLMVYGKRVRDALLKALGDNFYVELAMRYRNPSLEKKLLLLLNKGIKQLIILPLFPQYASASTGSVYQKSMEILKNQISLPKITFINSFADHPAVIQAFCHVALKNNLAEYDHFLFSFHGLPQRQVIKADKNNYCLKSQNCCQQACQENVDCYSAQCHLTAHAIIGQLNLPTEKTSLAFQSRLGKDPWLEPFTPHVIKELARQNKKKILVFCPSFVCDCLETTFEIGVEYAEEFKKMGGERLDIVQGLNDETAWIKALEKIVRENSSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRC4</accession>
    <name>A0A0C1JRC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IZ00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000157">
        <property type="protein sequence ID" value="KIC73735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73735">
        <property type="protein sequence ID" value="KIC73735"/>
        <property type="gene ID" value="DB41_IZ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1708"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="9"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="354" mass="40900" checksum="DDD0BA65BBD7BA2C" modified="2015-04-01" version="1">MNPCSSITIEHLPNEILVPILKVCAAPSLSSVCTRWRYLLATEVMPSLYKQISKMHFPAGDVNKQTFVLDRIYKLEEELSKAAKVNAIFRQTFTQARSISPLEFKGSIEEKRDFTLTNYRSYLVNINRLLIWKELRGGEEYLGKEEIKNLPLKERGRLFKEWVESYSKDIKKLNVARIGLTLLPSEIGQLSQLQTLELSNNQLTTLPAEIRQLSQLQCLYLENNYLTTLPAEIGQLSQLQRLHLENNQLTNLPAEIRQLSQLQRLYLNKNQLTTLPAEIWQLSQLQRLKLDNNQLTTLPTEIGQLTRLEKLKLSSNQLTSLPAEIGHLPNELNLYLDRNPLESIPNKIKQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRJ5</accession>
    <name>A0A0C1JRJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase</fullName>
            <ecNumber evidence="2">2.4.2.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">arnC</name>
        <name evidence="2" type="ORF">DB41_IY00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.53" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386079.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73805">
        <property type="protein sequence ID" value="KIC73805"/>
        <property type="gene ID" value="DB41_IY00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1694"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099621">
        <property type="term" value="F:undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="238" mass="27168" checksum="90FC5463A86A8B41" modified="2015-04-01" version="1">MTIQYSVVIPLKNEEDNIVELIEELEPIMLSLKKPWELICVDDGSTDQTLALLTHLLHKKNYLKLLIFKENYGQSSAFAAGFKAAKGEFVITLDGDRQNDPADIPKLVEAINNCDLVCGVRVNRKDPLSKKLISTVANLIRRSICEDGVSDTGCSLKIYRTSALHKIKMYNGMHRFLPALFKIEGLEVQEVAVNHRERIKGKTKYNFFNRSFNTIADLAAVRWMKKRQLKYQINKELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JS53</accession>
    <name>A0A0C1JS53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase, catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JK00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000167">
        <property type="protein sequence ID" value="KIC73311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73311">
        <property type="protein sequence ID" value="KIC73311"/>
        <property type="gene ID" value="DB41_JK00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1771"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="133" mass="15962" checksum="B57B3D736097D660" modified="2015-04-01" version="1">MDWYSRYVLSWRLSNTLDVDFCIEAVKEAFLKGIPEIFNTDQRSQFTSNRFVDFVREKNIAFSMDGKGRATDNIFVVRLWRSVKYEDVYLKDYQNGLEVYQGLTRYFKFYNKNRPHQSLEYKTPAEAYGIIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JT44</accession>
    <name>A0A0C1JT44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JD00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000161">
        <property type="protein sequence ID" value="KIC73611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386115.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000161.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73611">
        <property type="protein sequence ID" value="KIC73611"/>
        <property type="gene ID" value="DB41_JD00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="118" mass="13708" checksum="0C095701C982EAB5" modified="2015-04-01" version="1">MLKPKPTLQVVFYAESNGNEPVRKWLKSLDEETRFIIGTDVKKVQFRWPLGLPLVRNLGGKLWEIRSSIPNGIARIIFIISTNKMVLLHGFIKKTQKIPSQDFKLAKERIKNYEKKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUZ1</accession>
    <name>A0A0C1JUZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein ORF8 in nfe locus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243969.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74885">
        <property type="protein sequence ID" value="KIC74885"/>
        <property type="gene ID" value="DB41_IB00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="1">
        <location>
            <begin position="20"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="219" mass="25852" checksum="2B117EC9505A7A93" modified="2015-04-01" version="1">MIEWKQLEEEFDKLFVENVGQPAKPVRLVVELFILQHMYGLSDENVVYRWVENPYRQCFCGYHHFQHELPIHPTFLIKWRSRLGEARFSKILQGTIAAAVLTGTVKKKALKKVIADTTMMPKAIAFPTDAKLYFKSIQALVKMADNYQITLRQTYEKLAKTALCMRAGYAYASQMKRAKREEKRLNGYLGRLIRDFERKTEEQAFEPESSFFRNYHMYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV69</accession>
    <name>A0A0C1JV69_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">2-oxoisovalerate dehydrogenase subunit alpha</fullName>
            <ecNumber evidence="4 9">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">bkdA</name>
        <name evidence="11" type="ORF">DB41_IQ00090</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + 3-methyl-2-oxobutanoate + H(+) = (R)-N(6)-(S(8)-2-methylpropanoyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10489"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the BCKDHA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="4 9"/>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386041.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000148.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74306">
        <property type="protein sequence ID" value="KIC74306"/>
        <property type="gene ID" value="DB41_IQ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1659"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034616">
        <property type="entry name" value="BCKDH_E1-a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380:SF1">
        <property type="entry name" value="PTHR43380:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="E1_dh" evidence="10">
        <location>
            <begin position="32"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC74306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="358" mass="39944" checksum="74905471C210D107" modified="2015-04-01" version="1">MAIPTRTYLNAQGELSPECKVNIADEVLVKAYQTMVLTRRLDERMITLQRQGMISFALSSLGEEACSVASAAALSFEDWLYPQYRESGIIFWRGFTLQQYIHHMFCNKEDLILGRQMPNHFGSRALNVVQVSSPIGTQIPHAAGCAYAMKIQKENTVAVAYFGEGATSEGDFHVGLNFAAVRKAPAIFFCRNNGYAISTPASCQFTSDGVAPQVIGRNVTTYRVDGNDFFAIYEAVSQARQACIEGQGPVFIEAMTYRLGAHSTSDDPSVYRQEKEVLEKQLACPITRLKNFLEKKGLWDVQQEKSYLDSINKEITEAIQVAKETGRPALHSLIEDVYFEVPASLAAQYEDIQSLYHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV71</accession>
    <name>A0A0C1JV71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CG00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000252">
        <property type="protein sequence ID" value="KIC71147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71147">
        <property type="protein sequence ID" value="KIC71147"/>
        <property type="gene ID" value="DB41_CG00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="15463" checksum="8C7923757D90AFA0" modified="2015-04-01" version="1" fragment="single">YTIIFLPLQASHKSDPGKHHKSDTISQELEMEEQLKSKGKEKPTTHCRNKSIDSSRLHCKLRDNCFFILQFLQAQERQPNTFISLQDAKTKKTKESKKASASDHNNSTEEQEEAPQSSSSSSSSSNDSNSSSSDDSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV78</accession>
    <name>A0A0C1JV78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rpmJ</name>
        <name evidence="7" type="ORF">DB41_IB00980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385792.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74965">
        <property type="protein sequence ID" value="KIC74965"/>
        <property type="gene ID" value="DB41_IB00980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1532"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5188" checksum="994E5291839D16AA" modified="2015-04-01" version="1">MKVKASVKADPSKGDILVRRQGRLYVINKKDPNRKQRQKGPARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVM1</accession>
    <name>A0A0C1JVM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Holliday junction ATP-dependent DNA helicase RuvB</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">ruvB</name>
        <name evidence="8" type="ORF">DB41_HW00070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a complex with RuvA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385476.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75095">
        <property type="protein sequence ID" value="KIC75095"/>
        <property type="gene ID" value="DB41_HW00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1362"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00016">
        <property type="entry name" value="DNA_helic_RuvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041445">
        <property type="entry name" value="AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004605">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008823">
        <property type="entry name" value="RuvB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42848">
        <property type="entry name" value="PTHR42848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17864">
        <property type="entry name" value="AAA_lid_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05491">
        <property type="entry name" value="RuvB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00635">
        <property type="entry name" value="ruvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="53"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="61"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="333" mass="37187" checksum="E7B02440717B610F" modified="2015-04-01" version="1">MESKNYIESTLSQEDVTFEVPLRPQSLADFIGQDQLRERLTVLIEAAKQRKEALGHCLFSGPPGLGKTTLANILAKVMGTNIVITSGPVIEKPGDLAGLLTNLKDGDILFIDEIHRLNRTIEEYLYPAMEDFVLDLMIDSGPNARSVQVKLSKFTLAGATTRSGLLSSPLRSRFALNCRLELYPPEILVQILMRTGRILNLNIAPEAALEIARRARGTPRIANNLLRWVRDYAQIRANNKINPEVVSKALEMLSIDHKGLDEMDIKILETMIHHYKGGPVGLNTIAVAIGEEAHTIEEVYEPYLIMQGFIKRTPRGREVTSLAYQHLKLTINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVN1</accession>
    <name>A0A0C1JVN1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HW00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385482.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75100">
        <property type="protein sequence ID" value="KIC75100"/>
        <property type="gene ID" value="DB41_HW00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1368"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="509" mass="58332" checksum="B0A0FF8BAFF9E1D2" modified="2015-04-01" version="1">MTSVQAQKDYEALHEKSRYSRILSGITSILDWDQETYMPYAASAIRSEQLKVLAGIIHKSKTSPASAKSLAKLIDLETGKTIAKGLSAQQKAALQVWRRDYQQEKCLSANFVEEFTATTSQAIMAWRTAKQQNNFSILAPYLEKIIYMNRKKADLLGYQDHPYDALLDLYEPHTSTAEVATIFANLQSSLTNLLKKIKSSKKIDNSFLFGNFDPKKQLEFGHQLMNAMGYDQSKGRLDISSHPFSSASHPTDSRITTRLHPHSLMSSISAIMHEAGHGLYEMGLLPEHYGSPLGEAVSLGLHESQSRWWETRIGQSKPFWKHFFPLLQKMFPQQLEKISIPSFYKAINKVESSLIRVEADEVTYSLHIILRFELEKALIEGSLSVDEIPEAWNAKMQELLNLTPSNPAEGCLQDIHWSTGSFGYFPTYTLGNLYASHLFSAFEKQHPDWQEQVSRGDLLFIKEWLNLHVHRYGRQYDSKKLLKLVTKKEFNEEAYIDYLYNKYKSIYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW66</accession>
    <name>A0A0C1JW66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="3 13">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 14" type="primary">lpxK</name>
        <name evidence="14" type="ORF">DB41_II00110</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the LpxK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="3 13"/>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385906.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000142.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74626">
        <property type="protein sequence ID" value="KIC74626"/>
        <property type="gene ID" value="DB41_II00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1576"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00409">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42724">
        <property type="entry name" value="PTHR42724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00682">
        <property type="entry name" value="lpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 14" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="69"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC74626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="370" mass="41495" checksum="6A5A11234AD39025" modified="2015-04-01" version="1">MLKKLELYLVDLIQGKKQGALAHMAKTLLRFLSWIYQLIIAGRNWAFDQGCCKQYHAPVPVVISIGNIVVGGTGKTPVTLMVAQAFSNDFTLAILSRGYRSKAEHLPLPVILSYGNGPVHPAAYCGDEPYLLAQNLPKAHIIVGKNRQQSSKMAVRAGAQLILLDDGMQHRKLARDYEIVVVNALDPFGQGYFLPRGFLREAVSSLSRADLIVLNHIQDKEQFQSITKEIRKFSEAPLIATKMEVAEVLDLQGQPLAELVGKKVGIFCAIAHPDYFYQTVKQLGAEPVDTEFMLDHLTFTTESLIQFCERAKAKGAEWILCTEKDRVKLDELALSGQPIGWLKMNLKIVEGKIHWEGFIEKTKHYIKRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWM6</accession>
    <name>A0A0C1JWM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AU00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386851.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000217.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71622">
        <property type="protein sequence ID" value="KIC71622"/>
        <property type="gene ID" value="DB41_AU00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2230"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="90"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="189"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="239"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="289"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="339"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="389"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="439"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="488" mass="54485" checksum="8C373FB7CCF03F55" modified="2015-04-01" version="1">MKISQLPRAYVSINKIADYLPILSTVTNLLVIFQKCIILPFINEEKILKSDYYSYLDQKSFKRALLLLIPGLGNVIIGICDLAQRILKSKDFLLKALQKNSLVLKFASERLKNDKDFILTAVNKNPYVLQFVSKTLKNDPEVVWAATLQDPRSLRFASKKLKDDKDFILAAVQQNGLVLEHASEKLKSDTEVVLAALKQDLWALKDASQEFKNNKQAMLAAVQCNPWALKFASPQLQNDKDLVLTAVEKSGEAFQYASEELKNDKDFIFNASQKSYSMLKHSSEALRKDKDFVLALVQQNSWAIHDITKELKEDKDVMLAAVRQNGYLLLYTGTKLEDDKELGIAAVSQNGLVLQCASIKLRNDKEVVLAAVSQNGLALQYASIELQNDKEVVLAAISQNGLALQYASIELQNDKEVVLAAVSQNGFALKFASEELQEDKEVVVAAVKQNGLVFNHVSPYLRSDMEVGITAMLQNKEALKGEEGRKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXG8</accession>
    <name>A0A0C1JXG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidylserine decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.65</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">psd</name>
        <name evidence="9" type="ORF">DB41_AE00120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Phospholipid metabolism; phosphatidylethanolamine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386657.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71937">
        <property type="protein sequence ID" value="KIC71937"/>
        <property type="gene ID" value="DB41_AE00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2128"/>
    <dbReference type="UniPathway" id="UPA00558"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="303" mass="34164" checksum="988AEF3E637BBB68" modified="2015-04-01" version="1">MDIIYYLDRKNGKREIEKVYGARALKLLYGHDWISKLVGPVLLHSLVKYSFFSAWYGKWQASVKSKNKIEPFIREFGLDPLEFLEEVSYFKSFNDFFIRKLKPTARPLASGEEVAIIPADGRYLFYSDLSQVDGFIVKGEKFDLTSLLDDADLAAHYAKGAMAIARLCPTDYHRYHFPCDCVAGKTKIINGWLYSVNPAALKKDIHIFTKNKRTLCKLATSSFGCILFLEIGATNVGSIHETYQPDVLQKKGDEKGYFSFGGSSLILLFEPGKIQFDQDLLAASRQGLEIKCLMGQSMGKALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXJ8</accession>
    <name>A0A0C1JXJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_IS66 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HE00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75805">
        <property type="protein sequence ID" value="KIC75805"/>
        <property type="gene ID" value="DB41_HE00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="95" mass="10969" checksum="2C6C2ACFAF08A073" modified="2015-04-01" version="1">MRKFCHKLLKQIKHFHAYLKNPAIPMTNNAAEESLRNLVIVRKLCLGSQSIYGKRWREVLHSCIETLYRQGKSILDFLADAIHAARTKQPIPSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXT7</accession>
    <name>A0A0C1JXT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75880">
        <property type="protein sequence ID" value="KIC75880"/>
        <property type="gene ID" value="DB41_GZ00440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5183" checksum="F46ED37C2188D430" modified="2015-04-01" version="1">MAYGLDRLIFLRQAGKLSSSFQRGFWPRKSKSKHKAAYLILKING</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXU3</accession>
    <name>A0A0C1JXU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GZ00490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385002.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75885">
        <property type="protein sequence ID" value="KIC75885"/>
        <property type="gene ID" value="DB41_GZ00490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="312" mass="35845" checksum="D4F7110EF6417E82" modified="2015-04-01" version="1">MHPITNNSAISVSTILHERYFLELSPFESWPDELFLSILHYLSAVEMCQLRLVCKKFTQLSRDESLPIFIDESKDPNVSTLQWFCRQGQIKRVKQIIEAKNPSILCTFFKEQKSFLSEAVCSRQEELVHYLLSKGADAQVSDCNSKRGSTPLHLATKRGLMGITSRLLDYGADINVIDKKWKTPLHYTIGKKRFYPEIIKLLLAKGADLHVAGTLPFIYHAIEEGNFLATKKLLKLDKKRRKEGDSPLLDSSLDVKDFAKQKCKFLPNKNSTTERKARYEITVCIKKYFKHLQKLEKEALKNDICIISKDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYQ3</accession>
    <name>A0A0C1JYQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6444 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KO00150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386448.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72327">
        <property type="protein sequence ID" value="KIC72327"/>
        <property type="gene ID" value="DB41_KO00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="2">
        <location>
            <begin position="3"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="9859" checksum="26C264F6FE39B8B6" modified="2015-04-01" version="1">MKARIAQLEEQLNQNSKNSSKPLTTDQEASCSSLPQAENRPYHPGANRELLPARAVISYEVRSVEGCPHCYFLCMRLISFFLAADQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYR3</accession>
    <name>A0A0C1JYR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GN00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384805.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76115">
        <property type="protein sequence ID" value="KIC76115"/>
        <property type="gene ID" value="DB41_GN00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="509" mass="57579" checksum="97FA7CC2B340BED2" modified="2015-04-01" version="1">MNKLGGINSTAPSMHQIVQADSSQKDMLHPRPLCHRLHYVISNLGTQALQHLDAINDQGALKRGIIKGILTAAYLLNTVFASVELISALFFSVLAFSIQNFRKDSNSSIQKITLKSFAYTLNISAIVVEQFLQIINMSFSKYHSYNAFLNDGLPIFAMLSVLPFGSKTKLSKIKITPTSLFSYAEVRALRFLIDYTPSLLDNITKGAARDYAVYGAARKLSTHYPLSTDAFPSTFLRYYTPERQLNGEYYHYLLCLLLNAYQTSYLQEITQKLVLKPSPILTNIPEDESASFISNSLIADEKDAAYQNDLKYIIKLAYKNIYENPDLVCTLSQTLDEKKALIEGREILASLLATSQVANYAQFQEIISQIICPAKFNSPSLQVFNKRNQLITSARQRIAQLSVQEEDILINKLLKTGNYDLYAHPLTEERLKLIEGLFKDIVNLAGALYHGPLLLQNFNNLHQEACQEALTEIEKNENLINFLLNVPTLLKTLEMIFINKLHQIFFCHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZK3</accession>
    <name>A0A0C1JZK3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase_M48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_GD00080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76430">
        <property type="protein sequence ID" value="KIC76430"/>
        <property type="gene ID" value="DB41_GD00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.870"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="7">
        <location>
            <begin position="4"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="11345" checksum="F7A165B36CF4017E" modified="2015-04-01" version="1">MGSILKAAVSREREYLADACAVQFTRNSAGIIQALIKIERAEDEKMPLKGMAYSHLYFNDRMSLSSLFSTHPPIRKRIVALEGEEYIPIEWRHAKILDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZV4</accession>
    <name>A0A0C1JZV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GS00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000104">
        <property type="protein sequence ID" value="KIC75981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75981">
        <property type="protein sequence ID" value="KIC75981"/>
        <property type="gene ID" value="DB41_GS00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6885" checksum="900699B09E1325AB" modified="2015-04-01" version="1">MPAYSLTPMQTLRKWLKTVMFFHFKVLMIEINLLKGGSILSYREGWSVKKLKDRALRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZZ9</accession>
    <name>A0A0C1JZZ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FR00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000079">
        <property type="protein sequence ID" value="KIC76540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76540">
        <property type="protein sequence ID" value="KIC76540"/>
        <property type="gene ID" value="DB41_FR00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6710" checksum="C58F76E65489979D" modified="2015-04-01" version="1" fragment="single">WCEILFLPPYSPDLNPIETFWANFKKIVAANISNTLLSYSLCTPILHKIPFVKQRGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K015</accession>
    <name>A0A0C1K015_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase for insertion sequence element IS904</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nisX5</name>
        <name evidence="2" type="ORF">DB41_FP00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000077">
        <property type="protein sequence ID" value="KIC76550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76550">
        <property type="protein sequence ID" value="KIC76550"/>
        <property type="gene ID" value="DB41_FP00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.742"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="60"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="231" mass="27361" checksum="30630BB2E71D70DE" modified="2015-04-01" version="1">MRLIDEEYTRHPFYGSRKMTICLHNQGLKVGRRRISGLMKLMGIEAIYQKPNLSKPNAEHRIYPYLLRGLQINKCNQVWSTDITYIPMKKGFLYLTAVIDWYSRYVLSWRLSNTLDVDFCIEAVKEAFLKGIPEIFNTDQGSQFTSNKFVDFVREKNIAFSMDGKGRATDNIFVERLWRSVKYEDVYLKDYQNGLEVYQGLTRYFEFYNKNRPHQSLEYKTPAEAYGIIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K079</accession>
    <name>A0A0C1K079_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">gyrA</name>
        <name evidence="10" type="ORF">DB41_GN00110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243900.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76101">
        <property type="protein sequence ID" value="KIC76101"/>
        <property type="gene ID" value="DB41_GN00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.972"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="9">
        <location>
            <begin position="12"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="528"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="859" mass="96967" checksum="949F3AF727276534" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0D8</accession>
    <name>A0A0C1K0D8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">POTRA_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FH00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76625">
        <property type="protein sequence ID" value="KIC76625"/>
        <property type="gene ID" value="DB41_FH00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_1" evidence="2">
        <location>
            <begin position="93"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="319" mass="36723" checksum="49ED740CA3889F59" modified="2015-04-01" version="1">MILPPECFYHLHSFRLKILMRKKQEKLSIRTACLWIMLFTLAISGSAFVGLIYYKYIKRQRLYNSQYNIVAIAQTTPDKEPLKTAYLAELLNLSIDQPTNIFRFNTQAAQQKLLNSPLITHPYVKKILPGTIYVDYELRKPFAYLLDYHNTVIDREGVTFPFKPFFTPKKLPEIYLGITDASPLSWGKPLQEIKCKLALYLIDLLSTHCCSEYSYLSRVDVSQAFADSKGKRQIVAILDEQVEKTDQAGKLVKGIASHILRLSVDNYRQELANYLQLRPLLKYHMEDAQGGEAEKLLRFKPLVVDLRIPALAYIKSPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0E1</accession>
    <name>A0A0C1K0E1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FH00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76630">
        <property type="protein sequence ID" value="KIC76630"/>
        <property type="gene ID" value="DB41_FH00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4594" checksum="E0D4D20C82B6A733" modified="2015-04-01" version="1">MIINGLGFTLGLIHEGIKELILNLNHSMRHVLLVLVPFGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0H6</accession>
    <name>A0A0C1K0H6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD-box ATP-dependent RNA helicase CshA</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cshA</name>
        <name evidence="11" type="ORF">DB41_FB00120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384037.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76670">
        <property type="protein sequence ID" value="KIC76670"/>
        <property type="gene ID" value="DB41_FB00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.624"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="33"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="226"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="388" mass="44015" checksum="B52BC458030CF134" modified="2015-04-01" version="1">MTLFENMNLDPLILKSLERMQYKQPSAIQIQTIPLILQGKDLIALSKTGSGKTAACAIPICNKVNPDSPHVQALIIVPTRELAMQYATETQKIGYEKKVKAFAIFGGEDATMQQTKLKSGVQVLVATPGRLIDFIYSRQIDLTQVDILVLDEADEMLGMGFYDDLAFIINCLVHEHQTLLFSATMQEEIRSMAKKHMKAPQEISLLSDEVSPESIEHRFLYCRYDQRDQALLSLLEELKPKQTIIFCHSRIQCEKVCRTLQRKMADVDLLHAGLGQDVRSIITNKFRHGKIRYLVATDIAARGLDFSNITHVFIYQLSDSPDVYVHRSGRTGRQERAGVVVTLVTEKELKSLGRVLHHIRRKPIWIGNPPPERNHPRKRAVAHKNNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0I8</accession>
    <name>A0A0C1K0I8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JV00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386231.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000178.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73012">
        <property type="protein sequence ID" value="KIC73012"/>
        <property type="gene ID" value="DB41_JV00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="360" mass="41966" checksum="8A1CB9BBA55D98A7" modified="2015-04-01" version="1">MRNRKKGIAGKWSGESETTQLEESALALKIYNQRLLKVRIEGKDVWIKPDISFMNLGANELAVNSTSMGKHLKDAESLASYNAKGFIEFEQEVFDFLQKQSILPPSLMVTLQEIESMKGAPSLRQAKMDMQAIQNEKAKEIISLYASLDRLMEKYLSHPEKPDLKREIIRLKDKIEQHEKEVYNHYKDYLRLKSEVYIQKSSEIKNLFKKFRSQLKREIDQLPSDLAKVQQLQHINDLTLKFELAIDVFYRQKNKEVNSVLDFQVNYLEIHAMMSNCVEFFCKSAEDRTGRVDDKIQENKAFQAIFGRVPFGPEDQEYIDKFISPLIHQYSVSQNNTEKKFWRSRGADQPSTQSPFTCQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0J0</accession>
    <name>A0A0C1K0J0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
            <shortName evidence="6">DHNA-octaprenyltransferase</shortName>
            <ecNumber evidence="6">2.5.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">menA</name>
        <name evidence="7" type="ORF">DB41_GL00120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26478"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:11173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="EC" id="2.5.1.74"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MenA family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.74" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384742.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76271">
        <property type="protein sequence ID" value="KIC76271"/>
        <property type="gene ID" value="DB41_GL00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.946"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046428">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01937">
        <property type="entry name" value="MenA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004657">
        <property type="entry name" value="MenA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005355">
        <property type="entry name" value="UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="302" mass="33126" checksum="158F3B71A5F0CF41" modified="2015-04-01" version="1">MMNGNFLKKPAKWQAFTWAARPKTLILVVVPIFVGTLLALNYTSYFKGIAFASALLAGLFIQVAVNLINDALDFKKGADNAARLGPERATQKGWLSFHEVLYGGYFCLALAFILGMPMIMQGGILFLILLIVASLLAYGYTGGPFPLAYYGLGEFFVILFFGIIGTQAGFYLQAGKASEKAFLAGLQIGLLAAAVNAINNLRDIESDEKAKKITIAVKFGKTFARLEITLLILLPYFLSLLWSDLGFYKAGLLPFVTLPLGFTLIRCIWFYEPSKIYNTFLGVAALLNLLFGACLSLGFWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0L5</accession>
    <name>A0A0C1K0L5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JU00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000177">
        <property type="protein sequence ID" value="KIC73027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386225.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000177.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73027">
        <property type="protein sequence ID" value="KIC73027"/>
        <property type="gene ID" value="DB41_JU00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="160" mass="18290" checksum="26607F522A8D5B4A" modified="2015-04-01" version="1">MSAMLGKIKAWGLEIGKDPALINPVLQIKNIGKPPLYTEDQSERQFWSLKGRIKCVVMSCTFYVPRFIKVEAVAVARATKNLFKTRSTSDTATRERIWSKVRQNVHYFVWSHPLLYTACIVRLAAGVLHPGLSIGTKEEMPDFDWEDLENPYDSPKSKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0W3</accession>
    <name>A0A0C1K0W3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rplN</name>
        <name evidence="6" type="ORF">DB41_EI00050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383811.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76790">
        <property type="protein sequence ID" value="KIC76790"/>
        <property type="gene ID" value="DB41_EI00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.488"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="13289" checksum="3CC26D403FE05FAC" modified="2015-04-01" version="1">MIQQETQLKVADNSGAKRVKCFKVLGGSKRRYAHVGDIIVCSVQEAEPEGGAKKGDVVKAVIVRTAAPIKRDDGTVLKFDTNACVLIDDKNNPRGTRIFGPVAREVRDRDFLKIASLAPEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Y2</accession>
    <name>A0A0C1K0Y2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76436">
        <property type="protein sequence ID" value="KIC76436"/>
        <property type="gene ID" value="DB41_GC00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="5783" checksum="E0B10AECE730A43A" modified="2015-04-01" version="1">MLLTSSSLAKFKRSIERIMKGENVNAFPLTLYTAFKVCLSILLFIDSSNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K181</accession>
    <name>A0A0C1K181_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DZ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383702.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76880">
        <property type="protein sequence ID" value="KIC76880"/>
        <property type="gene ID" value="DB41_DZ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="1">
        <location>
            <begin position="139"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="227" mass="25432" checksum="A9A27B95CE5DC9E5" modified="2015-04-01" version="1">MLSENSRVHPLIFPAFKNIEEESISLRRNTYVYAEISLKIFAELNLPDLNQAKLVCRAWKQLIQSSNLLKKFDSVSPRITALKENSLEVDQADLLDPSANQWTPKQIAIFLWQNPTTIISDSLVAKVNAAAAYLKEEGFELKGVESDGDCFFSAFLESYAFLSRIIPLLEEQADKISYLRQVLSGIVKHTDSQRAEEIREKGAWISGLNEGDLLASALSIPNQTNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1D9</accession>
    <name>A0A0C1K1D9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_DS00060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383613.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76925">
        <property type="protein sequence ID" value="KIC76925"/>
        <property type="gene ID" value="DB41_DS00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="255" mass="29792" checksum="C81AC0722BCA5798" modified="2015-04-01" version="1">MQQEKIKAFEAKIKPVIEEYVNNQDFYLLASPLKTEHQYRLAFKEQIAKELNLTSLLQKYMKGINLLKIELLEKNDTYLMLKVLNEVEQAFKKIQEIQKNYSTSEDKEALAQNSLIDADQPLWTALYGLSSETLLLIYELAIKNFNNHACEDAKNLLQLLLTFSPTVSSYWNAMGYCYQNEGEYAKALNYYLMAEEIDPNFLETQFYLARCYQSMHQQGLALESLEKLWSFIHASPEVKEEWESHVRKLANEIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1H9</accession>
    <name>A0A0C1K1H9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FK00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384243.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000072.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76581">
        <property type="protein sequence ID" value="KIC76581"/>
        <property type="gene ID" value="DB41_FK00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.707"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="5"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="193" mass="21643" checksum="6E2B78F807B12FF8" modified="2015-04-01" version="1">MPFTLPIGASAPDFCLPATDGKNYSLKDFNSTSMLVIFFTCNHCPYVTGSDEVTRQTAEKFKNEGVVFVGINSNSAATVPADSFEHMQERMQTHHFPWYYLYDASQEIAKAYGALRTPHFFVFDQQRKLIYTGRGVDSPRDTSKVKHNDLEKAIAEHLAGGSVTTPLTNPIGCNIKWEGKERHWMPSDACDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Q1</accession>
    <name>A0A0C1K1Q1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgi</name>
        <name evidence="9" type="ORF">DB41_FI00210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384175.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76611">
        <property type="protein sequence ID" value="KIC76611"/>
        <property type="gene ID" value="DB41_FI00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.694"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="539" mass="60352" checksum="F6EA6EC74A4D6FC2" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K216</accession>
    <name>A0A0C1K216_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">nusB</name>
        <name evidence="8" type="ORF">DB41_DH00130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042242419.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77065">
        <property type="protein sequence ID" value="KIC77065"/>
        <property type="gene ID" value="DB41_DH00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.248"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="7"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC77065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="170" mass="19394" checksum="C189B9137B26FA9B" modified="2015-04-01" version="1">MALPLQKLREIIFQMLYSYDIGKAHQQDMIELMMKELAVSRASVIMAQQKVEEIQAIQEEIDGMIAGASFSYAFDRIQTVERNILRLGVYELFFASNIPPKVAISEAVRMSRKFSTPESANFVNAVLDTLYKARAGEEIDLQKIYKTIEEMTQSEEKSSSLPLEKEMAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K251</accession>
    <name>A0A0C1K251_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PI3K/PI4K catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EQ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000056">
        <property type="protein sequence ID" value="KIC76746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76746">
        <property type="protein sequence ID" value="KIC76746"/>
        <property type="gene ID" value="DB41_EQ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="1">
        <location>
            <begin position="37"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="299" mass="34226" checksum="7FA4F93A64756A87" modified="2015-04-01" version="1">MLHNREDGQIGSFQKYKEGVPLTDLPEIELQNIPSDELMKMLVMDIIMLNTDRHLGNAFLAPKDSIILIDQGSTFPGLASLKKGNTHDNLGFEWMFINFTQDKIPPAWQELILSIPPKELYTTLVEKLEELQSIYPDTPSLAIAGNVLFNSLVSLTFLQHWVKNMGQQLPSRELLRCFIPETIPYIYAVKKDSSKEITMLQEQSVHNFNRDRNSLANNLDTDMQEGKSGYFTTNPIFLSLVKDAYKDFENALALKNSEPISVQTFLKNWDVAEQTIMKRVIGLTFKETNQLAREYFSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2F8</accession>
    <name>A0A0C1K2F8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CT00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77190">
        <property type="protein sequence ID" value="KIC77190"/>
        <property type="gene ID" value="DB41_CT00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5271" checksum="496DECBAB4C5C15F" modified="2015-04-01" version="1">MSWENTSIKAKPSNLLARQALLKSNHPKGSKKAKTLLLKERRRDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2X9</accession>
    <name>A0A0C1K2X9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DH00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77056">
        <property type="protein sequence ID" value="KIC77056"/>
        <property type="gene ID" value="DB41_DH00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="281" mass="32432" checksum="9D220D8933735D15" modified="2015-04-01" version="1">MSRLITAKIPITILPPIGNSPPGYELLDIWPQKLMQTLSGPEEAIQSLKIRGLEVVFDLNEITKAELDAIHSAHLNAQNDEISFHIPNHWKEVAIPFHNNSLEEINDPEAQHLRIDFLRNEFISIDKEIPIRIFYPLKSLEEINPQTCTLAISDRVKERHGATIFNQKIFTKNVSSLFVEIIKPNMEIVISAAPKNERETLLWSLEVVAAEDLENTYVAYFMGDLLKSLYNPDIALSPQHQETLLRKRFRDYLQKLTLYSSPDQKLQIDSYWEDKFIKVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Z0</accession>
    <name>A0A0C1K2Z0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Core-binding (CB) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DH00140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77066">
        <property type="protein sequence ID" value="KIC77066"/>
        <property type="gene ID" value="DB41_DH00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="3">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7798" checksum="9282F962FE70CC34" modified="2015-04-01" version="1">MKRHLDWCRNKIGKYGLTKISPDLIAHCRQELVEGITSKKTKRSYSTVNRYLASLSTVFTYEVKACGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K344</accession>
    <name>A0A0C1K344_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retron-type reverse transcriptase, C-terminal half</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">revT1</name>
        <name evidence="2" type="ORF">DB41_CZ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243755.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77121">
        <property type="protein sequence ID" value="KIC77121"/>
        <property type="gene ID" value="DB41_CZ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.176"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GIIM" evidence="1">
        <location>
            <begin position="59"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="161" mass="18930" checksum="C931BDA41CD700E0" modified="2015-04-01" version="1">MLHPDKTKIIYCKDGSRKEKYEETKFDFLGYTFRPRLVKNSKRNSMFISFTPAVSQAALKSMKATIRQWNIRNRTDLELGDIARMYNPVIRGWLAYYGKYSPSALYQFCRHFNKTLVAWGMRKYKELAGHKTRTTIFIGKIVKENPELFVHWNKGMIGAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K380</accession>
    <name>A0A0C1K380_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CS00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77201">
        <property type="protein sequence ID" value="KIC77201"/>
        <property type="gene ID" value="DB41_CS00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.110"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="11866" checksum="43645CC0B2F7A12A" modified="2015-04-01" version="1">MIRKPYPSDLNNQEWQVLEPIICKKKAGKPPKHTRREMLNAIFYVLRTGCQWTDLPHDLPPWKSVYSQFLRWKQSHLFEQINAYLRRSLRQSLRQASGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5I8</accession>
    <name>A0A0C1K5I8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385933.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74547">
        <property type="protein sequence ID" value="KIC74547"/>
        <property type="gene ID" value="DB41_IJ00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013879">
        <property type="entry name" value="DUF1761"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08570">
        <property type="entry name" value="DUF1761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15181" checksum="90827022B63E9F9C" modified="2015-04-01" version="1">MELTNVNIWVVLVCTMINNFLASIWYSRKVLGDAWAKEHGFNVELLKPTPWHFAGAFLDAFILCFVLNMFFNNFAIHGMGNGMTIGFLIWLGFIATTHFSGVIWAKKPFKAYLIDSGYLLLNLILIGAIMGSWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5T4</accession>
    <name>A0A0C1K5T4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_II00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243984.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000142.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74622">
        <property type="protein sequence ID" value="KIC74622"/>
        <property type="gene ID" value="DB41_II00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1572"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="251" mass="28786" checksum="6ACAB7811B712515" modified="2015-04-01" version="1">MHKNFYIFLIAFFCCHFFQLNGQELYLKDKLRKATSGDYIVTLQNKTYTFLLIDTFASHEISLEEITVPSQSIQLEGFLWKKWVEQNAPGHTSWVRYVIDTASGHLGEYFSYTKNGWYTIPEGENFLSTLLNLKFYNIPIKERRKVGPPPPSQASDRRPYWQPKLVFEGKVIPGISFEAWRTFWPKDGSELSGKIIEIYLPQTAGIYPSYFPYWLQVSGIVGKAKIHMIDSGKGARGRGAPAKESPLRKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K673</accession>
    <name>A0A0C1K673_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IF00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385888.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74762">
        <property type="protein sequence ID" value="KIC74762"/>
        <property type="gene ID" value="DB41_IF00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134123" evidence="1">
        <location>
            <begin position="19"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="155" mass="17753" checksum="1E32DDFED5B38124" modified="2015-04-01" version="1">MTRFLFSLFLWASASLFAQNELPLASMEINNFLQSFDAAWNTHNIKALVSLWSPQGDFMTPQGRWIMNPTQLEKHFKSGKIGFYGKSTISQSLDAARLLNLELVIVDSTVRLDKGAKDDPLNSLLQHAVYVLTKKNEQWKILSLRMYQFQPQSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6P7</accession>
    <name>A0A0C1K6P7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385729.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74917">
        <property type="protein sequence ID" value="KIC74917"/>
        <property type="gene ID" value="DB41_IB00500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002148121" evidence="1">
        <location>
            <begin position="22"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="204" mass="23635" checksum="58BD6E1CAA7D3263" modified="2015-04-01" version="1">MNKIILSLIICLLAISCASRYGDFYPMHDDGKAKPRVVLLPTVDATEKSSSVDYLIKQTRHQLRERGSLYLYPQECVERQLEKIKKVSFFDPDFSFVKNFGGADVIVATELVEYRKDRYGEVEVKCMPPHLHNKNLLTMKLKVRMIDLRGEQPTVVLQEIMTEQLLLPPTACDSDKEKYYFKKLSERLVRDLITRLENVALHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6Z0</accession>
    <name>A0A0C1K6Z0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trxA_2</name>
        <name evidence="5" type="ORF">DB41_HY00230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243961.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74997">
        <property type="protein sequence ID" value="KIC74997"/>
        <property type="gene ID" value="DB41_HY00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1417"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134993" evidence="3">
        <location>
            <begin position="19"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="32"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="16379" checksum="2B4F0171DE00034C" modified="2015-04-01" version="1">MKKILASLSIFLNCSLLAAAPSSARHGVSQPSQARQSRPASSIIYLNADNFHQILNNPLPIILDVYTDWCGPCKQLAPIFEELNKELGNRYLFVKLNADEQKNLSDHFNVQALPTLIFIKDGKELGRSSGFVNKSQLTSMIKSYFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA85</accession>
    <name>A0A0C1KA85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug resistance protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">emrA</name>
        <name evidence="3" type="ORF">DB41_GP00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243904.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000101.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76032">
        <property type="protein sequence ID" value="KIC76032"/>
        <property type="gene ID" value="DB41_GP00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="430" mass="47719" checksum="76F3371E46A964E8" modified="2015-04-01" version="1">MKANEETSRMIEDTIKDSVARPQKTNKSSEKSPNPDNLDSQEPSSSPLSPSNTIKRNRKLWGFTLILALASLSWGLLYVLYLQGYETTDDAYASGNMININPSITGSVIAYYVDDTDFVTEGQLLVQLDQTEYLLKYEHSLASLASTVLKVRQLYEKVKASQSTLEARKIALSKANYDYENRSHLVGMQAISKEEYTHSKADLSIAKATHQIAEAELAAAIAAVGNTSLECHPLLIEAKSQVRKSYYDLQHCRIYAPATGYVAQRTVNVGQSVRPQTPLMAIISQNDYWVEANFKETQLKFMRIGQPATINFDMYGSKIEYVGKVVGIASGSGSKFSLIPPQNATGNWIKIVQRLPVRISVEPEQMKKYPLRLGISAKVKVDISNQDLPMLASTSPGRPLAATTVFNVHLEPIDHVIDEVIQANLKKKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAJ0</accession>
    <name>A0A0C1KAJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GN00170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76107">
        <property type="protein sequence ID" value="KIC76107"/>
        <property type="gene ID" value="DB41_GN00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="315" mass="36678" checksum="F56CD04F95F5FDC7" modified="2015-04-01" version="1">MVFLALHFSYRDKWMKERLLKALLSLLLAWRAEIAAMPEKKLEASNCESSLPVEAQPSQVSPKDRGLTQKNWAIAYYKDQEQEKSFKAFLESLKEVPAVEAVNISPDEKLIYEQALKIYLEDAGYDSDKTATKIISQFEPFFTKNPNFYHLSYLLAMSKANLGLYEQFFELFYNAYLHDPQHFLAYKAKAALYIKLFERAKTEEERQAARLQILSHARKAVAIEPYDTSLYRIILGFTQKDAKVQALSTYLNSIIEQNVVLSRIDIPYYVEIALAFHQYDLAQRLLDKAKQWYAFSRVINLAQKLLDEKRGHFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC22</accession>
    <name>A0A0C1KC22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FD00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76647">
        <property type="protein sequence ID" value="KIC76647"/>
        <property type="gene ID" value="DB41_FD00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.646"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="188" mass="20205" checksum="B95A7845F230EF8B" modified="2015-04-01" version="1">MVGTGLKVMAAGLFMVFLILAALYEKWSLPFSILMVVPFGLLGAFLAVWMNGMSNDVYFQVGLITLIALSAKNAILIVEFAVIKHQEGLPLAEAALEAGKLRLRAIMMTSLTFILGVVPLFMAKGAGAASRNSVGTGVLGGMITATFLAVFFVPFFYKLLEEIANWRGKKAGYPSTQTSKETSDKTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD49</accession>
    <name>A0A0C1KD49_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_DP00190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76967">
        <property type="protein sequence ID" value="KIC76967"/>
        <property type="gene ID" value="DB41_DP00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="10"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="811"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="866" mass="98143" checksum="6E9DF9B8544084A8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDJ0</accession>
    <name>A0A0C1KDJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DG00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000023">
        <property type="protein sequence ID" value="KIC77072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77072">
        <property type="protein sequence ID" value="KIC77072"/>
        <property type="gene ID" value="DB41_DG00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="10160" checksum="E9821F7D5235A7D2" modified="2015-04-01" version="1">MSFKFELSISHLYVCSMVYKDINRYFMGILREAVAVWGNLNRSCFGCYYTKMAILFKDYFNIMGKKLSLLPCPSYFSHRVFRRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDW8</accession>
    <name>A0A0C1KDW8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">murE</name>
        <name evidence="12" type="ORF">DB41_CV00100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383259.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77172">
        <property type="protein sequence ID" value="KIC77172"/>
        <property type="gene ID" value="DB41_CV00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.137"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="108"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="337"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="152"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="412"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="412"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC77172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="499" mass="55690" checksum="4E3BF4CEBAAD00C6" modified="2015-04-01" version="1">MKLKKLLKNISVQEVKGSKDVFITGICANSKVVAPGNLFVAKKGRMDDGAHYIHEAIEAGASAILTDIFDPSLQFITQIIHPQIPLVEPLLAAHYYQFPSQELFMVGITGTNGKTTTSFLVKHLLDHLKVPCGLIGTIEYIIGKHRYQATRTTPDVISNHKLLREMVLQDCKAAVMEVTSHALDQGRAVNIEYDVAVFTNLTLDHLDYHQSMDNYCQAKQKLFQTLNPEKNKTGKNYPCTAVINIDSPWHQMMVKGCRAKILTYGLSAAADVQAKNIVLTSLGTDFTIGYGGEEVACHCPLVGRFNIYNCLAAICVGLVRKEPLKKLVEIIASFPAVPGRMQAVYNELGLNIFVDFAHTDDALTNVLECLQEFKQGRIITVFGCGGNRDASKRPKMAQVAEKFSDYCIVTSDNPRSENPQNICQEIARGFNQQNWEIEIDRYEAIKKAIYMANPADVILIAGKGHEAYQIFSYKTIEFDDRKIAAQICLEKYKDEMIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE15</accession>
    <name>A0A0C1KE15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CP00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383157.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77217">
        <property type="protein sequence ID" value="KIC77217"/>
        <property type="gene ID" value="DB41_CP00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.76"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022550">
        <property type="entry name" value="NTP_transf_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12281">
        <property type="entry name" value="NTP_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="267" mass="30200" checksum="062E0B27EBB8B4E6" modified="2015-04-01" version="1">MSRELKREDCIVSDFLRSIGPWDNYIVLGGGYALIIYKLYLANQEVGIAPVGTHDLDSLIPRKVPSFMNKNIAYCLKESGFIPIFKDYGNPATEAYVKEINGFEVEIEFLTDSVTRGDKNKNVLIAGVVAQPLSYLSLSLQMTLSFVTYSGERGLVVSPGAWMFHKGLTFPKRNAPSKAYKDLYGIWYAATQLGEFSDKAVAELALLSQQHSKWFKTFQKNLHQWMENAAPIDWSRLEAQDPSGRLKKLNFEKIIKSIISRKENQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1T8</accession>
    <name>A0A0C1H1T8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386791.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71649">
        <property type="protein sequence ID" value="KIC71649"/>
        <property type="gene ID" value="DB41_AS00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="248"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="399" mass="45521" checksum="4632F1D5D3FDF115" modified="2015-04-01" version="1">MINLDSKELLETDFNALARKILTLENQTNNFNEKVDNLAKVILFKNERHEQHLKTLCEQNQLFMETIVKLKSDNIILTTENKVLKQEAQKWKNKASKTQAVMQLALQANEQFGEAVQALTTDKEKLSQENGSLKEDKARLTQASHAFKQDNANLRAENQIFKDKNQELNDDKRALENENKGLAIKVQAIEDKFQTLVKENEQLRDLEGRLHQQMTLLTQQAQETPTLPPKILKLMIDGGLKVNPDTPLTEAIRQIFEINENLKKKNKELQATLMRIESTLGLQRGVSCDSILRAINKAIVIPNKLKILGNKLVIANLLKKDYQPEDVLEILNGILNDYLDFRRYQPMICKELGIKATSNIETILKKMQEKKDESGVSAYFSRLGRSTLCLLSLGFAKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2C6</accession>
    <name>A0A0C1H2C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pathogenicity-related ORF2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">sctR</name>
        <name evidence="10" type="ORF">DB41_AF00100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71824">
        <property type="protein sequence ID" value="KIC71824"/>
        <property type="gene ID" value="DB41_AF00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2152"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005773">
        <property type="entry name" value="YopR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01102">
        <property type="entry name" value="yscR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002146343" evidence="9">
        <location>
            <begin position="36"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC71824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="295" mass="32908" checksum="CB65E5AC5D681D87" modified="2015-04-01" version="1">MAKTKAIIKRLFSLNCLSWMLVLALLCMISPECWAQSSPPRSTTSIEAGKAVVRPGEKTPAEKELDIRFDNFRKPSLITQAAVLSLLAMLPFIVMILSSFMKIVVVLSLLRSALGVQQSPPNQVINGVAFMLSIYVMYPTALKMYDASMQVVNQQAAPESLISAGSSAYIMALVEAGREPLRDFLKRNSSVKHHALFYRMAYRVLPDNYRPTLKPDDFMIVVPAYITSQLKDAFEIGVLIYIPFFVIDLVVSNVLLAMGMMMLSPVTISMPLKLFLLVMLDGWTMLIEGLVNTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H705</accession>
    <name>A0A0C1H705_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JM00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73264">
        <property type="protein sequence ID" value="KIC73264"/>
        <property type="gene ID" value="DB41_JM00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="223" mass="25636" checksum="B2682973327CE801" modified="2015-04-01" version="1">MNIKEAMRPYSKSKRVKKRFITLLELLMVMAILALTLGVIGFNVHKALREQRFKTETDLVVDYLRLAQNLMLIMNADVHVIFESAQHSQANLMRLKVEGNLDDKLLELVTNKEKPLHYIQLIEFYDENRTHHESSKIDVRFFSKGSVMSKGVMRLATHAQSNTSGTLERFIYLPGYPQPIVSALTNSPDFTSKEKQNADFEIKLINATVQEIQEKRLAKSNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8L2</accession>
    <name>A0A0C1H8L2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_14</name>
        <name evidence="3" type="ORF">DB41_BU00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000241">
        <property type="protein sequence ID" value="KIC71218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244131.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000241.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71218">
        <property type="protein sequence ID" value="KIC71218"/>
        <property type="gene ID" value="DB41_BU00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2306"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="359" mass="39994" checksum="0DC55308491D8AC2" modified="2015-04-01" version="1" fragment="single">EICQLSKLQTLILSFNQPTSLPAEIGQLSQLQNLYLNKNQLTNLPGEIGQLPQLQVLYLNQNQLTSLPGKIGQLSQLQGFYLNQNQLTNLPVEIGRLSELQRLNLSQNQLTSLPGEIGQLPQLQELYLNQNQLTNLPKEIGQLSQLQRLDLDQNQLTSLPGEIGQLSQLQGLYLNQNQLTNLPVEIGQLSHLQGLDLSRNELTALSAEISQLFELQTLYLGENQLTNLPGEIGQLSELQTLYLGENQLTNLPGEIGQLSELQTLYLGENQLTNLPGEIGQLSELQKLYLNQNQLTSLPKEIGQLSQLKWLDLDQNQLTSLPAGIGRLSELQGLNLNQNQLTNLPGEIGQLPQLQKLYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8W8</accession>
    <name>A0A0C1H8W8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein UmuD</fullName>
            <ecNumber evidence="9">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">umuD</name>
        <name evidence="9" type="ORF">DB41_IY00050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042243092.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73809">
        <property type="protein sequence ID" value="KIC73809"/>
        <property type="gene ID" value="DB41_IY00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1698"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Peptidase_S24" evidence="8">
        <location>
            <begin position="29"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC73809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="152" mass="17201" checksum="6F2B71AF932BBF20" modified="2015-04-01" version="1">MEETKAIQVPASEIQNILKFIQNKFYRIPLYQYRINAGFPSFGEGDIEKRIDLNELLIKEPDVTFLLKVCGDSMINAGIHHNDIIVVDRSIEPSEGKIVIASLNGELTVKRLRRVADRLMLVAENKAYAPIEITEDTELRIWGVAISVIHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9V6</accession>
    <name>A0A0C1H9V6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AU00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386854.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000217.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71623">
        <property type="protein sequence ID" value="KIC71623"/>
        <property type="gene ID" value="DB41_AU00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2231"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="80"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="608" mass="70194" checksum="FEFC11B9244F7A79" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAX5</accession>
    <name>A0A0C1HAX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74549">
        <property type="protein sequence ID" value="KIC74549"/>
        <property type="gene ID" value="DB41_IJ00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="7684" checksum="9668F43E433947FF" modified="2015-04-01" version="1">MGAIKKAEIVICHLKKWRWQVERAISWLQQKFRRIDVRWERQVKWWKGLLNFSLIMCWIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBR9</accession>
    <name>A0A0C1HBR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_IB00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385601.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74869">
        <property type="protein sequence ID" value="KIC74869"/>
        <property type="gene ID" value="DB41_IB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="22"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="709"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="781"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="824"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="866"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="908"/>
            <end position="941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="965" mass="111295" checksum="D13EDA67BE8FC700" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBS0</accession>
    <name>A0A0C1HBS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UVR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KQ00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386485.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72248">
        <property type="protein sequence ID" value="KIC72248"/>
        <property type="gene ID" value="DB41_KQ00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2018"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025542">
        <property type="entry name" value="YacH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38430">
        <property type="entry name" value="PTHR38430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UVR" evidence="1">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="186" mass="21027" checksum="6AA7AD9120B64D8E" modified="2015-04-01" version="1">MVKKAFEFFEEQVPERPIECTECKKPVAIWYTELIGNTVSQTSMCSDCPILRRKLHGQTSEKEMGHMVGETSLACGECNTSLESLRVGASLGCSNCYEVFDDIILQELLILDKVPPRVKANKKIFPLHIGRSPGEVREISPSLRLLALNEALNETIKREDYEQAAWLRDQIRALTEENVEKSNGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCJ4</accession>
    <name>A0A0C1HCJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385508.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75119">
        <property type="protein sequence ID" value="KIC75119"/>
        <property type="gene ID" value="DB41_HW00310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024492">
        <property type="entry name" value="DUF2764"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10962">
        <property type="entry name" value="DUF2764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="261" mass="30782" checksum="FF08615575091C79" modified="2015-04-01" version="1">MNRQYYFVGTLLPPLHLGEKPDISWRDLQRLLVDNLSEADYAQTQVLRRYYDLLNIRSYLKKEPIDKYGNLDLNELEETIVDEAALFPSYMMEYLERYESKEARIDHFPQLMAAFFREEVASTQGFLKSYLSFERNLRLILTAYRAKRLERNMAKELQFENFEEDIVVQLISQKDSKTFEPPAGFEELKTILDEKYNTPLALQKALNEYRLKTLEKIRSLNVFSFDSILAYLASFILVEKWSALDKEQGLQIVDTIIKGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCL0</accession>
    <name>A0A0C1HCL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KJ00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386372.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72533">
        <property type="protein sequence ID" value="KIC72533"/>
        <property type="gene ID" value="DB41_KJ00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="13465" checksum="F7F15178A294AA10" modified="2015-04-01" version="1">MVETTNVQSTASLSVRSLGDTVKSGATWLGRQFNHGARAIKTLVARMWFATVDFFKNFPAYLRSGYGVGAILGTAALSGLGASLTLKSKKQQVARAVATVAAGALLFVAGAVMFAFGCNPVTFSRHTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEB8</accession>
    <name>A0A0C1HEB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HF00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75774">
        <property type="protein sequence ID" value="KIC75774"/>
        <property type="gene ID" value="DB41_HF00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="236" mass="27710" checksum="E9B00B8A529BD29E" modified="2015-04-01" version="1">MHNQNTLVRNYSMLKDATYKEKSTMLISWMPQIIEEVKKDLKHEHLKNDFKFVKKYFLGKNLNKLTNEEIVNAYTLALEQEENGEKIAEFIINRWLLKNAELYDYFEGALLQISNDFTQLTEIDADKSQQIVEGAVSQYGAVRTYLFSVMNSVVFPKEIYEKLNKRAEEEQKALAAVEDAQDEHLSQQSLKDYYEEQIARLADKYEKKLIGMQKKYIQDTESLKKQMALLQKRLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEK0</accession>
    <name>A0A0C1HEK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase (Reverse transcriptase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JR00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000174">
        <property type="protein sequence ID" value="KIC73128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244032.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000174.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73128">
        <property type="protein sequence ID" value="KIC73128"/>
        <property type="gene ID" value="DB41_JR00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1811"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="265" mass="31668" checksum="712BDF74E6EE023E" modified="2015-04-01" version="1">MRAVKKHTENKWILLYIERWLKAPEQDADGRLIKRDRGTPQGGVISPLLANLFLHYALDEWMRKCYPRNPFERYADDIVVHCQTEAQANEIKKAIAERLAQCKLELHPAKTKIVYCKDDQRRKRYLNEKFDFLGYTFRARRSKNRYGKHFINFSPAVSNKAKKAITSTMRSWKMHLRSDKKIVDLSRMFNPMIRGWINYYGKYYKSELYQIFNVANRTLARWAERKYKKLRGHSRRAMHWLGGIAKREPQLFAHWKMGVIPATRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HET8</accession>
    <name>A0A0C1HET8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">groS</name>
        <name evidence="3" type="synonym">groES</name>
        <name evidence="5" type="ORF">DB41_GU00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042240868.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75954">
        <property type="protein sequence ID" value="KIC75954"/>
        <property type="gene ID" value="DB41_GU00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1020"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="108" mass="12182" checksum="04104FA4F624B261" modified="2015-04-01" version="1">MEQTQTKEKQNLNIKFKPLGNRVLVRRLEQEEKLKGGIILPDSAKKKQEQAKVVAIGTGKKDKKGQLIPIPVNIGDIIIMEKYSGQDIKLEDEEYVILKADDIIGIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFY5</accession>
    <name>A0A0C1HFY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76299">
        <property type="protein sequence ID" value="KIC76299"/>
        <property type="gene ID" value="DB41_GK00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="281" mass="31640" checksum="0E8E8E793A62E22F" modified="2015-04-01" version="1">MIKNFCSLIALDIDGTLAVKMQNIPPTVIHYLTTLHQQGAMFVFVTGRTFEFGHQVLKELPFSYYYAAHNGAILLSMPDRRVIIKNYLDGSVLLSMEKICESTSTDFVIYTGLEGNNLCYYRPSHFSPNLRYYLEKRRQSFNEEWIAVKNFKEIPFKEFPSIKCFGEEETAQYVAERMEKNLELHAPVIKDPFGEGNYVVQATHSQANKGYALRQLIDQLGYEGVVIAAGDDLNDLSMFEQAHIKVAMADAPLQLKAKADIIAPPASSLGIIKGLEEALAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGC3</accession>
    <name>A0A0C1HGC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4135 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GF00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384590.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000091.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76414">
        <property type="protein sequence ID" value="KIC76414"/>
        <property type="gene ID" value="DB41_GF00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4135" evidence="2">
        <location>
            <begin position="160"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="530" mass="60931" checksum="114E088DB08764D2" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGG0</accession>
    <name>A0A0C1HGG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-threonine 3-dehydrogenase</fullName>
            <shortName evidence="6">TDH</shortName>
            <ecNumber evidence="6">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">tdh</name>
        <name evidence="9" type="ORF">DB41_GC00110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384512.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76444">
        <property type="protein sequence ID" value="KIC76444"/>
        <property type="gene ID" value="DB41_GC00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.840"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00627">
        <property type="entry name" value="Thr_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004627">
        <property type="entry name" value="L-Threonine_3-DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00692">
        <property type="entry name" value="tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N" evidence="8">
        <location>
            <begin position="26"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="7">
        <location>
            <begin position="174"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="286"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom" evidence="6">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="344" mass="37604" checksum="A26FFBDA4405BE82" modified="2015-04-01" version="1">MKALVKSYRKEGLWMEDVPIPSIKEDEVLIKTHKTSICGTDIHIYKWDAWAQKTIPVPMVVGHEYMGEIAEIGKNVKGLKVGDRVSGEGHITCGSCISCLKGQKHLCINTLGVGVHRHGCFAEYFNIPAENVFPLPPSIKDNVASIFDPYGNAVHTALTFDLTGEDVLITGAGPIGIMAAAIAAKAGAHQVVITDVNEYRLQLAKKLGAQTIVNVANTSLKEVMKALDIQNGFTVGMEMSGHPDGLRTLLENAHHGGKIALLGILPAECLIDWDLVIFKMLTIKGIYGREIFSSWFKMVNLLESGLEIEPLITHHYPIDKFETGFEVMMSGQSGKVILDWLEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGW6</accession>
    <name>A0A0C1HGW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IW00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000154">
        <property type="protein sequence ID" value="KIC73903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73903">
        <property type="protein sequence ID" value="KIC73903"/>
        <property type="gene ID" value="DB41_IW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="258" mass="29999" checksum="915607812FC84903" modified="2015-04-01" version="1" fragment="single">MVNNMTPFSLIPSIRIPEEVQLKILSLLDEKELPIAGLVNKHWQRMAQDPSLWRPICQRRWKNLSHSSSPGKNWRKICKKQAQMSKTMRLTKGEYSKNKCKETIYKLPNFSGKILALKREKQFAFIKATAGTAQIYHLGEKSCQLVYDNVKEENSRLIHYQEGHIIQVTQEGQLYRWKVNEAFPQTSLCYLGNFENAYLAQNHLFLVNPHRTQFKIVDVRTGLSYHKNTCAPISFILCRNNQALIHCLDGSLYFINDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH58</accession>
    <name>A0A0C1HH58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDE Tnp4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_FI00290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76619">
        <property type="protein sequence ID" value="KIC76619"/>
        <property type="gene ID" value="DB41_FI00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="3">
        <location>
            <begin position="9"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="95" mass="11113" checksum="71C47F9D2009791E" modified="2015-04-01" version="1">MLQKRLLSALKKQKRYYSGKKKKHTLKTQVVVDKKSKKVICTSFGNGKKHDFRLFKESQVKINPQIRVLTDSGYQGLTKLHAQTQDLRKKVRRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHB2</accession>
    <name>A0A0C1HHB2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DB41_EZ00010</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000062">
        <property type="protein sequence ID" value="KIC76689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76689">
        <property type="protein sequence ID" value="KIC76689"/>
        <property type="gene ID" value="DB41_EZ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.607"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="12">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="589"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="631"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="673"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="757"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="799"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="841"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="980" mass="111614" checksum="61AB6C710115C2C5" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI02</accession>
    <name>A0A0C1HI02_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein kinase PknD</fullName>
            <ecNumber evidence="7">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">pknD</name>
        <name evidence="10" type="ORF">DB41_DP00010</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="PTM">
        <text evidence="7">Autophosphorylated on serine and threonine residues.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76949">
        <property type="protein sequence ID" value="KIC76949"/>
        <property type="gene ID" value="DB41_DP00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.335"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01957">
        <property type="entry name" value="PknD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023507">
        <property type="entry name" value="Ser/Thr_kinase_PknD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="81"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="87"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1025" mass="118319" checksum="520F784AF5A29216" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI48</accession>
    <name>A0A0C1HI48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DN00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76984">
        <property type="protein sequence ID" value="KIC76984"/>
        <property type="gene ID" value="DB41_DN00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018687">
        <property type="entry name" value="DUF2177_membr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09945">
        <property type="entry name" value="DUF2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="5916" checksum="2C41E16B95F7F717" modified="2015-04-01" version="1">MHPGLISVLSSLFFMLAIDAVWLGWMMKGFYRSNIGHLMNDSPKIIPATFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIB5</accession>
    <name>A0A0C1HIB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DM00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000029">
        <property type="protein sequence ID" value="KIC77019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77019">
        <property type="protein sequence ID" value="KIC77019"/>
        <property type="gene ID" value="DB41_DM00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="203" mass="23885" checksum="E04614EB02AD5038" modified="2015-04-01" version="1">MEFNQILFTLRKIKAIKRRKNSMELQALARNYFKSFHEILNYQKNCAQLNALALLKIFSYFILVIPISFAAVYAVASLYGRISKNPSLSKQDQQPSNRTAKTFFSVHFPKPIPPFSPSKNCRVNIQPFINEAKIFAQQRHNAYGDPDKLLKYIHNKLETKEFQTNPRLFMNKWKKERGLTDELRVPEDQAMAFFERKVMPHIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIQ9</accession>
    <name>A0A0C1HIQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CX00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383298.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77139">
        <property type="protein sequence ID" value="KIC77139"/>
        <property type="gene ID" value="DB41_CX00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="37561" checksum="15E3A6BD4B3DA4B4" modified="2015-04-01" version="1">MASLNIHRPPRLPCNHSFINEGNQKNEKAAFYWKIKHLALLALATLCSLATLTGVINLFSSTSFSVLSKYTFILSAGALGVFLSGNMLNSMASRLPQSLVSLANYIYSIVCEFFSLIALNFLRFVDLEKRDPHKGNEQQPILLIHGLYSNSGSWAYYRYRFSKEKLGPVFTVHLGKPFESIEIHAEKVRNKVLEIQRVTGRNDITLIGHSMGGIVACVAASKLAECNLLVTDIITLGSPLKGAFLAAWGIGKAVKEMHPQSAFLANLSKRILNLPSTTHFFHIASKTDLLVPLSSALFNETIYTKRLTLSNVGHLSLLFSDSLIEEVINYYKIRQNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIS9</accession>
    <name>A0A0C1HIS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">rsmH</name>
        <name evidence="7" type="ORF">DB41_CV00070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383255.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77169">
        <property type="protein sequence ID" value="KIC77169"/>
        <property type="gene ID" value="DB41_CV00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.134"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="34"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="310" mass="34651" checksum="026298CB5C498EF5" modified="2015-04-01" version="1">MSSSPHFSVLLPEFLSFFADKTIRGFVDATLGAGGHSAALLQAHPEVNRLVGFDQDPVALSLAKSRLITWESKIDFFKLNFVHMKGSLSAYPVPIDGILLDLGVSSMQLDTASKGFSFSKEGPLDMRMDPSQDLTAEEIVNTWSEQELGKIFREWGEEKQWHTAARILAKVRQEKPLKTTQDLVEALLPALRYRAKKGIHPLTLIFQALRIAVNRELEVLEKILPDALSLLTPGGRLAVITFHSLEDRLVKNFFRFAASDKYETSGIGGMFLDKSPEAHILTRRPLVASEKEINQNARSRSAKLRVIEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIY5</accession>
    <name>A0A0C1HIY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CP00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77229">
        <property type="protein sequence ID" value="KIC77229"/>
        <property type="gene ID" value="DB41_CP00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5281" checksum="E4F58A4956F3F4D0" modified="2015-04-01" version="1">MAFSLATLSLDKLWFIFLFSLVKGYFFHFFLGLWVWACSFLNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLB1</accession>
    <name>A0A0C1HLB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HT00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000130">
        <property type="protein sequence ID" value="KIC75198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385444.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000130.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75198">
        <property type="protein sequence ID" value="KIC75198"/>
        <property type="gene ID" value="DB41_HT00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="584" mass="64532" checksum="F27BD46EDBF9C997" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN43</accession>
    <name>A0A0C1HN43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DB41_HG00130</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385169.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75758">
        <property type="protein sequence ID" value="KIC75758"/>
        <property type="gene ID" value="DB41_HG00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1184"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="218"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="290"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="444" mass="51288" checksum="02FF7C12EAE736F9" modified="2015-04-01" version="1">MFFLTLFFLLGSFLLTAVISSFRRMHKKDAQKQIKAMNSFFLYRSFHHIFFPHHEYESLFFTAICAQNLARFGYTACGIIFLSQTALFNSLRERPDYLNTLWIIISLLILILASFVLGDYLPRLLGTHLPEKALKIGFSFSSVYFFLAFPLAFIFLKISHLRSYDLYFDSTQVPSAQAKKEIIELIQEAEVSPTLNFHDKKLIESVLTFKERCAREVMVPRLNMFSLSADTSIKEAARLLQHEGYSRTPIYRHSLDNIVGVLMYKDVLKKYMEYEEKKDSRILDTPIEAIQKSILYTPETKKISNLLQEFRQKQVHFAIVVDEYGSTEGIITIEDILEEIVGEIADEYDQEEETVKQLADGSWIIDAKMSIFDVEAQLGIQIPQEEEYDTVGGYVFHLAGAIPSTNFIIHHDNFELEILESSDRSVEKVRIKPIESSPLLNEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HND0</accession>
    <name>A0A0C1HND0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">gmk</name>
        <name evidence="11" type="ORF">DB41_HC00050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="JRXI01000113">
        <property type="protein sequence ID" value="KIC75828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385052.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000113.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75828">
        <property type="protein sequence ID" value="KIC75828"/>
        <property type="gene ID" value="DB41_HC00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1132"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="9"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="193" mass="22177" checksum="8FD9200878B8BC8B" modified="2015-04-01" version="1">MSSSKQYTGRIFIISAPTGTGKTTLVKRLVQELSNVKPSISYTTRKPRLGETDGVDYNFIDKNDFEAKIKAGEFLEYVELYGFYYGTSRVWIEEQQQKGYHIVLVIDTQGGLKLKDKIQGTFIFLAPPSLEELRKRLLARQTESLSVIEERLSCVSREIEQGKKYDYKIINEQLDVAYEALKSIIVAEMHRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNW4</accession>
    <name>A0A0C1HNW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH-quinone oxidoreductase subunit C</fullName>
            <ecNumber evidence="2">1.6.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nuoC</name>
        <name evidence="2" type="ORF">DB41_GS00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.99.5" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000104">
        <property type="protein sequence ID" value="KIC75978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75978">
        <property type="protein sequence ID" value="KIC75978"/>
        <property type="gene ID" value="DB41_GS00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex1_30kDa" evidence="1">
        <location>
            <begin position="8"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="11033" checksum="4F4ACB7061DB2FE7" modified="2015-04-01" version="1">MRIISYTESDMLLPSVTDIWEEAEGYERQLFNLFNVRFTEHYTPKGILVAKEWEKPSSSQGYVQQEEYMKFKTYLSNQDPSLIIPCVHANPPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQM0</accession>
    <name>A0A0C1HQM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GA00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76478">
        <property type="protein sequence ID" value="KIC76478"/>
        <property type="gene ID" value="DB41_GA00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4337" checksum="50E9E90D23D935A2" modified="2015-04-01" version="1">MRRPGSSGRSFAAITEDRLPKRQCTALREALEETFALGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQM6</accession>
    <name>A0A0C1HQM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal RNA large subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.191</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rlmI</name>
        <name evidence="6" type="ORF">DB41_GA00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.191" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384439.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76483">
        <property type="protein sequence ID" value="KIC76483"/>
        <property type="gene ID" value="DB41_GA00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.809"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA_3" evidence="5">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="165"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="388" mass="44011" checksum="866A95B2FCB1B1E3" modified="2015-04-01" version="1">MLVKKVTLKVGKEKAILNRHPWIFSGAVAHLPQNLCGEILPVYSHHGDLLGSAYFNSKAKIFGRMLSFGSQPPLEAFKNNLELATALRTKFFSSDTTAYRLINGEGDFLPGLIIDRYEKGFVVQISTLGMENLKPYLLDYLIETFQPAFIYEKSLLLSRKEEGMKATEQLLYGKLEEEVSIRENGIKFLVNPVQGQKTGFFLDHREMRAQVKNLSKDKRVLNCFAYTGGFSIYAAAGGAIQVDSVDISKVALNLAHKNAELNGVSSCMHFYPKDVFQFLRESSLDYNLIILDPPAFDKHRKDIIPACRGYKDINRIALQKMPSQSLLLTSSCSYYVNDQLFQKVVFQAAVEARRQVRIIGRHRLGIDHPLNIYHPEGDYLKSLWLYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRC8</accession>
    <name>A0A0C1HRC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384046.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76678">
        <property type="protein sequence ID" value="KIC76678"/>
        <property type="gene ID" value="DB41_FB00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="8719" checksum="9D59B8A5465CB236" modified="2015-04-01" version="1">MAFHPHKDLKYILHPYIFVLKENQGIHNDLFDYSLWMMRISPETIRSPKGVEGKKGIVGDDFDAFQAHLNFSSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRN1</accession>
    <name>A0A0C1HRN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EJ00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383862.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76783">
        <property type="protein sequence ID" value="KIC76783"/>
        <property type="gene ID" value="DB41_EJ00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="SSF54695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="484" mass="56217" checksum="ABED0138CD5D3B94" modified="2015-04-01" version="1">MKYSKLEKEEELIEQLSRHSADLVSFFLVACNDELWIESYPNSMKAFFKWLTDAHIHTNLPYHFFHQVIPPTYQHMEFLKAFIPLDLTIKSGEQEYLFNSLLLSHHSYYFRRRIMKECPNAERRILKIDGILPQTMEVIEKFVLKNIAEDVWKKPLEELWALLKDLEILGFAALREACERVLHRYINRNNVVEILIKAHHQSLLLLKNGCIEFINQLDWGMRFLVTLINHLSIEFLNYNAIALEVFNILSPYITHLTFSGAMTASPYFKMITNRTPHLIGLDLSESTIFSDYLVDLPPTLQELCLSHCPWVNAEALNTLANTCPHLLRLDLSSNEHLNYGIWPHLQHLKQLKILDISRCLQINDNDLKMIIQACPYLIELSLANCQKINGEAFFHLGRLLPNISALNFSRTLLIDAALIDIMMHCKNLYFLDISRCESLSEKGVLEGIKSCPSLKKILLKHSPISKNGIEQIRKTFPYLELETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS58</accession>
    <name>A0A0C1HS58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DS00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383617.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76928">
        <property type="protein sequence ID" value="KIC76928"/>
        <property type="gene ID" value="DB41_DS00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="463" mass="53724" checksum="C3AE31A31D623C50" modified="2015-04-01" version="1">MDKEKNVSTRELQAAIKILESFSYRKETSSSVSILKKTMTFAKQLFSISSVKVEEKKNLQQALALIKNSFSLIQSLAEGTFRQKQIASSAYTAIDRFNALSSPLKRRPLPWRRWMDTLLIKIPKREKRKEKISLGKEVSCKFYSQEDEKIKLPLPPFSQGELLPTTQEIDAFRMKAITLLKHHEVRFTSLTEQLNIIREMPIVIKEQTPLSKAIAESVVALEQTISSFPGETIELKGTFKRSLKSKGPSIPIPESFHITTQSQQTGYPHPSQHHGWVLSPFLLPKDHALKDKMQEIANELKPTGRFNLQAKAFLKAKQECFNQHVTEFLSLHLQLNECMLKIIGINEKTILNSFYKHLFQHNNPYHYLSYLHQIIIHQYLEKRKDSLKAALYTPTELEYIYQIGNFYEISMEKHLNLLEELALKQLHDFLMEIEKEKVLSPSAMYHWLKEMLLNDINFFSSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS62</accession>
    <name>A0A0C1HS62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitrogen fixation protein NifU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_DS00140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383628.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76933">
        <property type="protein sequence ID" value="KIC76933"/>
        <property type="gene ID" value="DB41_DS00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.387"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="4">
        <location>
            <begin position="15"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="NifU" evidence="3">
        <location>
            <begin position="187"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="262" mass="29118" checksum="DE3FFEFA4FC34839" modified="2015-04-01" version="1">MGILQFVHPFTWTRYSKKLINKIDHPYCGGIFLKEDAAEREMLFIEGSAGSLEEGNIISFYWLVDKDDGVIVDAKFQVFGHTALIGASEIACELLVGKNYLQAQRMNADLIDRQVRDRADEAAFPHETYSHLNLVLEAIEKCAEQCIDIPLADSYLTTPVPIGMDNVIPGGYPGWKELSLKKKLAVIEEVLDQDIRPYIALDAGGVSVLNLLEDKELIIAYHGSCTSCYSSIGTTLSYIQQIIRAKVHPEINVIPEMKGITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS73</accession>
    <name>A0A0C1HS73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DQ00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76943">
        <property type="protein sequence ID" value="KIC76943"/>
        <property type="gene ID" value="DB41_DQ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4594" checksum="E80CB293C6CDE8D9" modified="2015-04-01" version="1">MSKKKHFWHGQKSLQTLQAVYYVFFKESSIHPKKGLAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSB9</accession>
    <name>A0A0C1HSB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DN00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76983">
        <property type="protein sequence ID" value="KIC76983"/>
        <property type="gene ID" value="DB41_DN00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018687">
        <property type="entry name" value="DUF2177_membr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09945">
        <property type="entry name" value="DUF2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="79" mass="9086" checksum="2ADEB1B0EC715062" modified="2015-04-01" version="1">MPHVYLSWFIPSLHQKTSYLNTFLTGMLFGFATWATYDLTNQATLKDWLLIATLVDVGWGSFLIGTISRLTLYFVSRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSF7</accession>
    <name>A0A0C1HSF7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ntox28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DN00290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383521.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77008">
        <property type="protein sequence ID" value="KIC77008"/>
        <property type="gene ID" value="DB41_DN00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028948">
        <property type="entry name" value="Ntox28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15605">
        <property type="entry name" value="Ntox28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="28"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ntox28" evidence="2">
        <location>
            <begin position="170"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="953"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1149"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1385"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1734"/>
            <end position="1769"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1917"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="2082"/>
            <end position="2114"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="2115"/>
            <end position="2147"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="2211"/>
            <end position="2243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="2320" mass="262989" checksum="49DB04892047A4A7" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSZ8</accession>
    <name>A0A0C1HSZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CU00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000011">
        <property type="protein sequence ID" value="KIC77183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77183">
        <property type="protein sequence ID" value="KIC77183"/>
        <property type="gene ID" value="DB41_CU00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="10258" checksum="5B7F7ED395C0C6D1" modified="2015-04-01" version="1" fragment="single">TFALASFLSPLELEFKWITEEKRYFTLANYSSYLVNINRLLMWNRIPGGKHYLDQEAIKYLPLEKKESFLVIGLKGMAKTLRAYAYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT74</accession>
    <name>A0A0C1HT74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein ORF8 in nfe locus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CK00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77273">
        <property type="protein sequence ID" value="KIC77273"/>
        <property type="gene ID" value="DB41_CK00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="1">
        <location>
            <begin position="53"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="113" mass="13611" checksum="A6C341B9DF578894" modified="2015-04-01" version="1" fragment="single">MKPIKLDNQQGRLFNPRFSDELNLDHPLIQLSKLIEWKQLEEEFDKLFVEKIGQPAKPVKLVVGLFILQHMYGLSDVNVVHRWVENPYWQYFCGYEFWHHALPIHPTSLIKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT82</accession>
    <name>A0A0C1HT82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xaa-Pro dipeptidase</fullName>
            <ecNumber evidence="5">3.4.13.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pepQ</name>
        <name evidence="5" type="ORF">DB41_CK00110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.9" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383058.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77283">
        <property type="protein sequence ID" value="KIC77283"/>
        <property type="gene ID" value="DB41_CK00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.25"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102009">
        <property type="term" value="F:proline dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="4">
        <location>
            <begin position="6"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="3">
        <location>
            <begin position="135"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="347" mass="38757" checksum="6B0C63D7AEB82650" modified="2015-04-01" version="1">MNFQNRLAKVEKVLHDSNVEAFLVEDPTNLYYLTGLVLSAGKLLIKTQGNSTLLVDNRYYEYCKNQAPVPVFLSDKNSLESLLGGVNTLAFDGETISYQTYASMQENFKDLKLVSLSHSLQKIRSLKDAHEIAILQEAAQLGMQGYEYIKSLLKEGVREDQLAAELEIFWKKNKAQGVAFEPIIAFGANSALPHYRPAETELREGMTVLFDVGVKWKGYHSDLSRTLFWGEPPAIMRKVYAIVEKAQQRAMALCKPGITIGELDRAARDYISACGYGEHFLHSLGHGVGLEIHEWPSLRNKEPYQQLPLQEGMVITIEPGIYLPGIGGVRIEDTLLITSTGYQVLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK13</accession>
    <name>A0A0C1JK13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase, IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AU00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386859.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000217.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71625">
        <property type="protein sequence ID" value="KIC71625"/>
        <property type="gene ID" value="DB41_AU00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2234"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="2">
        <location>
            <begin position="4"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="128"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="541" mass="61875" checksum="ACDD47A915C23507" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKK0</accession>
    <name>A0A0C1JKK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AF00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71820">
        <property type="protein sequence ID" value="KIC71820"/>
        <property type="gene ID" value="DB41_AF00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5237" checksum="E35CCC651EC87662" modified="2015-04-01" version="1">MIDLKKARSFFSFSCFYPKNPLLLAAQLKAKGRNTYFLFKAYQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL01</accession>
    <name>A0A0C1JL01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative polysaccharide export protein wza</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">wza</name>
        <name evidence="4" type="ORF">DB41_AD00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000204">
        <property type="protein sequence ID" value="KIC71965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71965">
        <property type="protein sequence ID" value="KIC71965"/>
        <property type="gene ID" value="DB41_AD00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2113"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040716">
        <property type="entry name" value="Wza_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18412">
        <property type="entry name" value="Wza_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Wza_C" evidence="3">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="364" mass="41063" checksum="F562D41DDD306AF5" modified="2015-04-01" version="1">MPLSEKRKKVKVNFLFSPFVLLNVSLLIIFASCSTANFDYPIMGPDEFVIDSYRIRQGKLAILELEGVELGELAEEDMLEYRDVIAEDDILNIAVYHPTRKDLMQSIQFINESTGGFKVYQGKIDVPDLPPLAVKGLTLEEAREELQRAFRDQIQDIEVYVNYRDRLQRRVELIGLVSIPTVPVDGKMRLYEVLARSHIPPGANLFKSYVMREGRQLPIDLHRLINEGDMKQNIVMRGGDKIFIAAPSDATVMVMGEVRAPRPINVPYGFISLREALVTAGGIPFTGNGNCIHVIRGNMLCPKVYLVSLDHIVHLPNDSLLLMPGDTVYVAEKPLTQWNRFIEQLIPSFTGLQAGYGTYQLIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLD6</accession>
    <name>A0A0C1JLD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KV00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244079.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000200.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72090">
        <property type="protein sequence ID" value="KIC72090"/>
        <property type="gene ID" value="DB41_KV00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2066"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="207"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="293" mass="32333" checksum="CAB3039B4493DBE8" modified="2015-04-01" version="1">MQPTNNEQSGATSSSTASSSEPQQSSSSWNARTWSPSSSFQPRPFQPRPFQPTSFRPTSYTSASTSPSPVVNGQSNFQSPPPALNPSCLASVFHETAIQAPSRDCQKLVMQSLKKGTLSIKEEREMLEEIKASSAEQLTQTMTWRKQIDENITSFYDESMKMNKLYSSLAFKIANALKDATIASIRTGEALQMDYLELTQEEFKNYKEIMLAAVKQNGLALQFASRELKEDKEVVLAAVRQNGLALQFASQELKENKEVVLAAVKQNGLALQFASQELKNGKDIVLAAGQEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQ09</accession>
    <name>A0A0C1JQ09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JK00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000167">
        <property type="protein sequence ID" value="KIC73310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73310">
        <property type="protein sequence ID" value="KIC73310"/>
        <property type="gene ID" value="DB41_JK00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="10824" checksum="CEBA906EDDB9D0D6" modified="2015-04-01" version="1">MSTKRKRHSSEFKAKVALEAFKGFKTINELATEYSVHPTQISQWKKHLIEALPVLFSSMDKVSKTDQKLVDNLYQQIGRLKVELDWLRKKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQ55</accession>
    <name>A0A0C1JQ55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KF00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000187">
        <property type="protein sequence ID" value="KIC72641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72641">
        <property type="protein sequence ID" value="KIC72641"/>
        <property type="gene ID" value="DB41_KF00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="133" mass="15241" checksum="63A97EDCF93DA83B" modified="2015-04-01" version="1">MLVPGNVETQVPVSDLSKNIFGKMFADKGYISHQLFIKLYDKGLEIITRLRKNIKNKLMSLVDRILLRKRGIIESVNNKLKSSCQIEHPRHRSPWDFFVNLISGIAAYAYEPCKPCIQFTSAEKQKLMSCPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSS1</accession>
    <name>A0A0C1JSS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JH00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386134.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73541">
        <property type="protein sequence ID" value="KIC73541"/>
        <property type="gene ID" value="DB41_JH00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1744"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="284" mass="32780" checksum="C085DB50D840F14E" modified="2015-04-01" version="1">MTADLEKSLKARLRVIAKETRRDPADLWQNLILERFLVRLAKSNYRERFVLKGAVLLSKYINLGRETKDLDFLANGISNRVDDLSLIFEEVSKIELDDGFTFQNIKVDQLTHPHMRYSGAEISAMAYFGQIKRKLSIDIGFGDIVEPIQYSIPLLKGAKGAIFESSVNLSCYPKEFIFAEKLETIVYRGFLNSRMKDFHDVHSLILNEFSASFHNLKLIIESVFEHRGTALKLPIAYKIAELPQLRTFWQSYLNGLKIDENTLPKNFDDLLSRINEWLVSKDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTU8</accession>
    <name>A0A0C1JTU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74530">
        <property type="protein sequence ID" value="KIC74530"/>
        <property type="gene ID" value="DB41_IJ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="77" mass="8487" checksum="9D2B574351B1B8D0" modified="2015-04-01" version="1">MIGIFLSALAALFILFTPFTPVNLPNENLLGCLLLITGTTFFVLFCLTIAGSLIPLQKAGQNSTPYLLSLFKRDKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTW5</accession>
    <name>A0A0C1JTW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74545">
        <property type="protein sequence ID" value="KIC74545"/>
        <property type="gene ID" value="DB41_IJ00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4829" checksum="5E50DAE3C8FD992D" modified="2015-04-01" version="1">MQEYLTEDKHSYRLKNFTSYVLKNDQLSAIDNIKSFSYTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUY1</accession>
    <name>A0A0C1JUY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385607.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74875">
        <property type="protein sequence ID" value="KIC74875"/>
        <property type="gene ID" value="DB41_IB00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1440"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026362">
        <property type="entry name" value="DEXH_lig_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017170">
        <property type="entry name" value="Lhr-like_ATP-dep_RNA_helic_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045628">
        <property type="entry name" value="Lhr_WH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19306">
        <property type="entry name" value="Lhr_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037307">
        <property type="entry name" value="Lhr-like_helic_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04121">
        <property type="entry name" value="DEXH_lig_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="28"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="239"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="803" mass="90809" checksum="CE130F44766F8618" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVY8</accession>
    <name>A0A0C1JVY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385941.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74556">
        <property type="protein sequence ID" value="KIC74556"/>
        <property type="gene ID" value="DB41_IJ00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="328" mass="37268" checksum="250060B8F79E2D9C" modified="2015-04-01" version="1">MSSLTISSERSPFIPSSLSQEKTTRFPRESLQRFSPEVILGLMQRRGDLDNPLSSYKIKGTPSRGEWHYFKSPRRNLPSSSLSSKAPVVSSERARSEKINFFSKEAIKEIGCETVILTIAHLLKALNSSGFQEIKIGGITATALLPILMINFNRLAPQFPTEKVQLYGLGYSAEQKEFLNLSIEALLKTRGKKNITITGFSEANLLQNINLQEKYERHIGTFDIIYTNLSLDKLSELKALLKVGGALIFKETLIIQKRAKSHENLLSEEENNYYKKFQEVFDSIHAPVEHHLPLYAICKKILQSGFHFHKRNISSSYQPTYVFLLINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW38</accession>
    <name>A0A0C1JW38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">hflX</name>
        <name evidence="10" type="ORF">DB41_HS00030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385430.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000129.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75305">
        <property type="protein sequence ID" value="KIC75305"/>
        <property type="gene ID" value="DB41_HS00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1330"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="9">
        <location>
            <begin position="218"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="224"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="249"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="271"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="337"/>
            <end position="340"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="362"/>
            <end position="364"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="441" mass="50209" checksum="7E6F5034E03E37DB" modified="2015-04-01" version="1">MPSIKPKILESSEDEYQQPKKALLVSVYKGSNFRTICEEHLDELALLAETYGIHVNSKVPCMVRKYDASTFVTEGKLQELLRMAQEQKVDLVIFDDEISPGQQRNLENIFKMPVIDRTGVILEVFAQRAHTKEARLQIELAKIKYQAPRLKRLWSHLSRQAGTGGKSGGAYLKGEGEKQIEIDKRILKKQMDSLQNEIHEVRANRLTQRTLRTRLEIPVFAIIGYTNAGKSTLLNALTDAKVFVEDKLFATLDTTTRKYLLPNNQEILLIDTVGFIRKLPHLLVAAFKSTLEEALQADILLHLVDISHPMAEEQAATTYEVLKELNAENKPIITVLNKMDVCNDPQKITRLRILYPKSVCISALNKIGFEDLLEQMIQELNRRRTSVTLKIPQLEYHKVSEVMRLGNIIHQDYEENDVLIRVDLPCALAGKLKNYIIEGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWM9</accession>
    <name>A0A0C1JWM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative NTE family protein YlbK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ylbK</name>
        <name evidence="4" type="ORF">DB41_IE00070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000139">
        <property type="protein sequence ID" value="KIC74841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74841">
        <property type="protein sequence ID" value="KIC74841"/>
        <property type="gene ID" value="DB41_IE00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="62"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="93"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="351" mass="38694" checksum="92A8AF62EB09498B" modified="2015-04-01" version="1">MRFPINKTLLTVEKKIRFFTALMFLLLLFSVSGCRYSHRLVPTVNPPSVPSFYVPKKIRVALVLGSGGVRGMAHVGVIEELEAAGISVDLIVGCSAGSIVGALYADNPCAKYIKEAVWNLKAASLLDFDLWQCRYGLCQGRSLSRVLNKYLKSETFEELKIPLVIVASDLHSGELIPIGSGDVEKAVQASCSIPFIFVPQEHLGRILVDGGVVNPVPVEVAFDIGAELIIAVDLCELLPRTFPTNLFEVATRSAEIAFMWQNETCCHHADVIIRPKTCDIGTFSDHLRDQIYEAGRRAAREKIPDILKKLDALKANSINDSLEEDDWCLYSPQCYIPQIYLKKTAPGSAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXL6</accession>
    <name>A0A0C1JXL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="16">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="16">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16 20" type="primary">metG</name>
        <name evidence="20" type="ORF">DB41_HC00020</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="16"/>
    <dbReference type="EMBL" id="JRXI01000113">
        <property type="protein sequence ID" value="KIC75825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385049.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000113.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75825">
        <property type="protein sequence ID" value="KIC75825"/>
        <property type="gene ID" value="DB41_HC00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1129"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 16 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="12 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 16 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 16 18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16 17" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TRNA-binding" evidence="19">
        <location>
            <begin position="584"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="16">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="16">
        <location>
            <begin position="332"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KIC75825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="683" mass="77570" checksum="8F879CF515A66023" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXW9</accession>
    <name>A0A0C1JXW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">cysS</name>
        <name evidence="13" type="ORF">DB41_GX00030</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000109">
        <property type="protein sequence ID" value="KIC75905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75905">
        <property type="protein sequence ID" value="KIC75905"/>
        <property type="gene ID" value="DB41_GX00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1059"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="365"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="282"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC75905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="482" mass="55433" checksum="F56DC03DC108B052" modified="2015-04-01" version="1">MIEQAEKSKNSLKFFNTEKRTKEIFKPFDDRMVRMYTCGPTVYNFAHIGNFRTYIFEDVLRRTLKFFGYKVMQVMNLTDVDDKTIKGAIAHNITLQEYTKPYIQAFFEDLKSLNIEPAEHYPAATDYLEDMIQMIQTLLHKGVAYKGGDGSIYYAIRKFPRYGCLSHLKLEELQTGASERLTADEYDKESASDFVLWKHYNAERDGKIFWESPFGPGRPGWHLECSAMAIKILGESIDIHCGGVDNIFPHHENEIAQSEAYSDKIFVKYWMHAEHLVVEDKKMSKSLGNFYTLRDLLEKGFTGPQVRYMLLQTHYKTQLNFTFPGLESVKAALQRLNDFIQRLLTYNKGNEKGLVGPLVQKAYHAFNHALADDLNISVALAAVFELVREVNAISDTQNMSVTEAQEVLQAMRQFDSVLGVLNFEKVNEDIPDELQQALLNRTKARENKDWAQADALRDFIVSKGYLIEDTPEGARLKKTENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY69</accession>
    <name>A0A0C1JY69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GR00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75990">
        <property type="protein sequence ID" value="KIC75990"/>
        <property type="gene ID" value="DB41_GR00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4582" checksum="70FC75ABA6A549D6" modified="2015-04-01" version="1">MAGGQLLVSPARGGGQKFMSPGGQFVMSLDRKEQEENISSARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY98</accession>
    <name>A0A0C1JY98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GQ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000102">
        <property type="protein sequence ID" value="KIC76015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76015">
        <property type="protein sequence ID" value="KIC76015"/>
        <property type="gene ID" value="DB41_GQ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.999"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="151" mass="17002" checksum="CC518DDDB99910B2" modified="2015-04-01" version="1" fragment="single">TSLPAEIGQLPELQKLYLNLNQLTSLPGEIGQLSQLQWLDLNLNQLTSLPGEIGQLSQLQLLELNQNQLTSLPAEIGRLSQLQLLYLNQNQLTSLPAEIGQLSQLQWLYLNQNQLTSLPGEIGQLSELQELELAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYZ5</accession>
    <name>A0A0C1JYZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000192">
        <property type="protein sequence ID" value="KIC72432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72432">
        <property type="protein sequence ID" value="KIC72432"/>
        <property type="gene ID" value="DB41_KL00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7790" checksum="BD719FD7FDDFF416" modified="2015-04-01" version="1">MLYLNQNQLTSLPARIGQLSQLQTLELNQNQLTSLPAEIGQLSQLIELELAENPLEDISEKIRERFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ52</accession>
    <name>A0A0C1JZ52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384668.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76295">
        <property type="protein sequence ID" value="KIC76295"/>
        <property type="gene ID" value="DB41_GK00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="497" mass="57671" checksum="CC9F9E35F034107C" modified="2015-04-01" version="1">MQDDLPIHNTLERQLNEMALAAGRKRQSKQTGFIHYFYPEPEDDLSQTIPVAENVWFILALLRSKTGEQIAEAKDSLERLLYFQHPLDGNFPVYMHEYPHCKDKFFGAQLLPAFYYILKEFHAVLGVDLRHRLESTISHLLSFLLKAYTEQASTYSIGLKIAAAAKMLGIELKNKAFETYGEQLLQQLLSMKMQAAWFIPSFIADVCIALQLAYTHIQHSEWLAFWQHLAATWHAPTKSYIGPWLKLYQARDEPQPTLYDLYLGYFGKEFSSRALKEAAYHLQAVQIRPTGEFLPVKSLPFTFAGSWQENRWLTHQEKTFAYSLIDKKALFKGFEENTFHPLSIIWGNEHKVHSFVCQKSNWENLEFNIKDQEIELDFALSAVPELEEREKCRELSFFFDVDPTAEISLEGQLASTFELGETFILNTSHIALSLRIVKEAGEGKFMGHLMRGNRSSQNQLKGINRFQSYDWNVFIRTLRRQATCKLKVRLQIMRCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZF1</accession>
    <name>A0A0C1JZF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nodulation protein NolG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nolG</name>
        <name evidence="2" type="ORF">DB41_GZ00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75846">
        <property type="protein sequence ID" value="KIC75846"/>
        <property type="gene ID" value="DB41_GZ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1075"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="835"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="890"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="935"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="968"/>
            <end position="994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1019" mass="112316" checksum="88F9E8BB3EAD2948" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZK9</accession>
    <name>A0A0C1JZK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GC00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76435">
        <property type="protein sequence ID" value="KIC76435"/>
        <property type="gene ID" value="DB41_GC00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.829"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="143" mass="16111" checksum="ECB84DB08ABE2B6A" modified="2015-04-01" version="1">MLYLNDNQLTTLPAEIGQLSQLGTLGLSRNQLTTLPAKIGQLSQLGYLHLYNNQLTSLPAEIGQLSQLQMLDLNNNQLACLPAEVGQLSELRDLDLRHNQLTTLPTEIGQLPKWLKVFLNGNRLENISNEIKQHVRLYLKNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZN0</accession>
    <name>A0A0C1JZN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0235 protein DB41_GC00170</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GC00170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384522.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76450">
        <property type="protein sequence ID" value="KIC76450"/>
        <property type="gene ID" value="DB41_GC00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00634">
        <property type="entry name" value="UPF0235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420">
        <property type="entry name" value="PTHR13420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="SSF69786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="10537" checksum="7226075B9D32282B" modified="2015-04-01" version="1">MSKSNLAPIYLPIKVVLKAKKSEITGWENDRLRIRLSAIPEKGLANDELLRLLSITLGIPKTSLQIVQGKTARLKIVRIERLSSQTLHPILLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZT8</accession>
    <name>A0A0C1JZT8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GA00090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243862.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76485">
        <property type="protein sequence ID" value="KIC76485"/>
        <property type="gene ID" value="DB41_GA00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.812"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134449" description="BON domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="3">
        <location>
            <begin position="97"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="169" mass="17995" checksum="4E6E4051276302A1" modified="2015-04-01" version="1">MKNLFKLSLATMTVLAGASMLHAQAVTSQEGLSNLEKSSYLNSAPSQTETKNSSVNTSGVQTPGHSTGQTYTQPSNLPRHSDAKISYSETKKTAAWTDGDISQKIRWAIKDDKKLSSYAKTAEVSVNNGNVIIAGSVNSEDEKNHVASIARQVPGVKSVSNNLVIANSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZW1</accession>
    <name>A0A0C1JZW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GR00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75991">
        <property type="protein sequence ID" value="KIC75991"/>
        <property type="gene ID" value="DB41_GR00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="74" mass="8588" checksum="4A6085E50DC0F827" modified="2015-04-01" version="1">MFYSHFYETMTLLIASLNDNFGPLFLLLLFQVAILKWLSTHIVCHSTSNCLQKSSIPQKMEIDQWITFSIISAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZY5</accession>
    <name>A0A0C1JZY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FU00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384350.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76530">
        <property type="protein sequence ID" value="KIC76530"/>
        <property type="gene ID" value="DB41_FU00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="683" mass="77317" checksum="1264F84A5E2BC5A3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Q1</accession>
    <name>A0A0C1K0Q1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EQ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000056">
        <property type="protein sequence ID" value="KIC76745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383924.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000056.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76745">
        <property type="protein sequence ID" value="KIC76745"/>
        <property type="gene ID" value="DB41_EQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="113" mass="13299" checksum="5B95D7C84A07F5F8" modified="2015-04-01" version="1">MNVSHNESISLQDRINNKGLFKYESLVSKKTQVAVIAFTYFDDQWEMTCANSALYQSFYQKGIAVPKDKRSFFQDRKVITMEDNLFPIAFFEILAPHRFPPDQYEYKGELKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0V7</accession>
    <name>A0A0C1K0V7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thymocyte nuclear protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thyN1</name>
        <name evidence="2" type="ORF">DB41_GG00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042238818.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76401">
        <property type="protein sequence ID" value="KIC76401"/>
        <property type="gene ID" value="DB41_GG00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.893"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="1">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="175" mass="20287" checksum="2FDB3B040546E9E0" modified="2015-04-01" version="1">MASNTQYWLMKTEPSVFSIDDLQREGFSEWEGVRNFQARNFMRDRMKEGDLVLFYHSNAKPSGIVGICRICREAHADFTAWDKDSPYYDPQATPDHPIWMMVEVEFVKKFSQVIALSELRKYPQLEGLKILEKGSRLSITPVEKKHFEFIESLGQLRVESDQNICSSQAQPTQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Z2</accession>
    <name>A0A0C1K1Z2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DI00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383445.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77050">
        <property type="protein sequence ID" value="KIC77050"/>
        <property type="gene ID" value="DB41_DI00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="22139" checksum="BDBBC2B7ECAF5C75" modified="2015-04-01" version="1">MSFFGTSNYSKVIEPTLYIHIPKTAWNTFTGKLREYYFLWRWKTAYLDQEDGAQPRKILICTSVRDSKISDRLNKLIGKSWCITNLINRDSYHEIFRKEFLSLSGQNEPGVTKTTHTLGETVGTYLRGGSDLFCYIYRQRSFFSLCRYHLLKNFLDYWKEISIQVGQISEKIVIKKFDEAAISRSGLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K293</accession>
    <name>A0A0C1K293_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DA00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000017">
        <property type="protein sequence ID" value="KIC77115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77115">
        <property type="protein sequence ID" value="KIC77115"/>
        <property type="gene ID" value="DB41_DA00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="74" mass="8874" checksum="99B0DAAF32FDF61E" modified="2015-04-01" version="1" fragment="single">HNKEHIRLYYFPSYCPELNPDEFLNQDVKSHIGKQCLHTKAQIVKLLNSHLKMRQKQPYVIQNFIKGCYPRYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K297</accession>
    <name>A0A0C1K297_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase (Reverse transcriptase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CZ00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77120">
        <property type="protein sequence ID" value="KIC77120"/>
        <property type="gene ID" value="DB41_CZ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.175"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="198" mass="23631" checksum="B9624205DA26CA6D" modified="2015-04-01" version="1" fragment="single">RNPFERYADDLVVHCQTEAQANEIKKAIAERLAQCKLELHPAKTKIVYCKDDERRKRSLNEKFDFLGYTFRARRSKNRYGKHFINFSPAVSNKAKKAITSTMRSWKMHLRSDKKIVDLSRMFNPMIRGWINYYGKYYKSELYQIFNVANRTLARWAERKYKKLRGHSRRAMHWLGGIAKREPQLFAHWKMGAIPATRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2C0</accession>
    <name>A0A0C1K2C0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CX00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77145">
        <property type="protein sequence ID" value="KIC77145"/>
        <property type="gene ID" value="DB41_CX00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="107" mass="12939" checksum="CBE92FAFB72DD35C" modified="2015-04-01" version="1">MLPEELIVHIFSFLSATNLATAQRVCKHWRKIAEEDSLWQRHHQRRLGCKPLMRIFSKRVPYSFKQSYLIYCKNEAECIRFKEMLAFSHDENLAFEHQLLEHYISKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2F6</accession>
    <name>A0A0C1K2F6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="1">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">coaE</name>
        <name evidence="2" type="ORF">DB41_JH00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386141.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73547">
        <property type="protein sequence ID" value="KIC73547"/>
        <property type="gene ID" value="DB41_JH00080"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="201" mass="22843" checksum="0B232E584F51EC63" modified="2015-04-01" version="1">MLALSKVAVTGGLSCGKTSVCHFFKRFGAYVVSADDIVHRLLSPTTNLGQRVILLIGSDIVINNQIDRSKISQKVFKQPLLLKSLESILHPAVQDEIKKHYDLANQQKIRKKLFVAEIPLLFEARLENFYDTVISVVADSDKSKKRFQKATGKSIEEYERRSARQLSIDEKAHRADYVIVNDSNLYDLEIETKKLMNILTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2G2</accession>
    <name>A0A0C1K2G2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_CS00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383207.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77195">
        <property type="protein sequence ID" value="KIC77195"/>
        <property type="gene ID" value="DB41_CS00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="88"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="789"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="595"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="896" mass="102081" checksum="632DA073173BD8D9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2I6</accession>
    <name>A0A0C1K2I6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JG00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73572">
        <property type="protein sequence ID" value="KIC73572"/>
        <property type="gene ID" value="DB41_JG00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5167" checksum="E50F9D72E05CA3D4" modified="2015-04-01" version="1">MKAVQETRLSLKKPPKSSEEYLAILEKQSLPQTVAYLKDYEWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2K0</accession>
    <name>A0A0C1K2K0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DU00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000036">
        <property type="protein sequence ID" value="KIC76906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383669.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76906">
        <property type="protein sequence ID" value="KIC76906"/>
        <property type="gene ID" value="DB41_DU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="466" mass="52985" checksum="801E261275EE1226" modified="2015-04-01" version="1">MPYHLTNHPRKYDLSYKDIGLSLITGLSGAPYASRHWQLSNYAKAKHCLGHRLIACIESIPFAGALAAIAERIIVFIQEKLLKDGRPTKHKAGTSPSCHTIANTLAVSHLASISSPLHQTSILGLLDHGQYSLQDKRSRETYDRKEPQELQVLLKRSVENIANIYEASRKLMKPSRSKQYSLLVSEVEEEIAKIKILGKVLTDKDQLVESKQIEDQEKVLKQMYKDMPLGESVLLRWDIEMMKGMSRRPAEKIYTTPCGTFENPNVSHLELSRWFSTYITEGDFFGFCCMFREHELGEEKDLNRMFTCINLTKNDDQRKIERKLYNGTPSLWKNIQSSLFSIGRTLLSKDQSSDEAEEKKETQALSLPSKDACEAGFISLPIKPISNYQIKQQKVLAKLAQDLPAMMEVWNVNSFQILTSEQMLAEGYEYEVAYSGDRILLFHKQVENQEVAIAAINPLPPPVKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2P1</accession>
    <name>A0A0C1K2P1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CK00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383053.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77280">
        <property type="protein sequence ID" value="KIC77280"/>
        <property type="gene ID" value="DB41_CK00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021521">
        <property type="entry name" value="DUF3185"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11381">
        <property type="entry name" value="DUF3185"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="6991" checksum="2E72021D61733A42" modified="2015-04-01" version="1">MRILGLVSLAVGIALLLFGINSSQAFTEKVVEDVTGRYTDNTMWYIIGGIAMIVGGGALTLFGRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K366</accession>
    <name>A0A0C1K366_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transpeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CV00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383257.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77171">
        <property type="protein sequence ID" value="KIC77171"/>
        <property type="gene ID" value="DB41_CV00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.136"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transpeptidase" evidence="1">
        <location>
            <begin position="277"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="680" mass="77092" checksum="7EB4366DEE84558C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3C8</accession>
    <name>A0A0C1K3C8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IY00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73817">
        <property type="protein sequence ID" value="KIC73817"/>
        <property type="gene ID" value="DB41_IY00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="53" mass="6283" checksum="38C0210D761B0EDA" modified="2015-04-01" version="1">MVNYLKPKLSKHDLTLVKKMKIKSHISACFFQGVTGRLPRFKAFQQMLKIFVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3W8</accession>
    <name>A0A0C1K3W8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IV00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000153">
        <property type="protein sequence ID" value="KIC74017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74017">
        <property type="protein sequence ID" value="KIC74017"/>
        <property type="gene ID" value="DB41_IV00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="157" mass="17818" checksum="FEA8F0941C92C928" modified="2015-04-01" version="1" fragment="single">RKKKIEFTMTPRPVEKCWNKKSILTISSYDGKRLAVGLSTSLIITYNPDDGNFLTEANIGLVAPVRFLALDDNYFLASHFHPEFKSFDLYQHTPIIECCGALWPLPPSEYPLVDSNTIHASYDGRKLVFCDEHGWLHLWDFAHLQGKEAILVAPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K857</accession>
    <name>A0A0C1K857_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ribonucleotide transport ATP-binding protein mkl</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mkl</name>
        <name evidence="5" type="ORF">DB41_HN00040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042238981.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75372">
        <property type="protein sequence ID" value="KIC75372"/>
        <property type="gene ID" value="DB41_HN00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="29368" checksum="90B84BE3E3562B50" modified="2015-04-01" version="1">MAIIEVQNLHKSYGALKVLKGLTLNVYEGETLVILGRSGVGKSVLLRQIMGIEFPDQGTININGKVLHSLSQHEQLKVTKEVGMLFQGAALFDSMNVGENTAFYLRQHEKEVDEREIQQRVAEALAIVGLSGKQKAMPSDLSGGMRKRAALARLVIYRPKIILYDEPTTGLDPITAQQINQLINTTKHELKATSIVVTHDIHSAMEVGDRLAFHHDGKLIHITSKEEFIKIDDPLINAFFENAIVTRAYSPSSNYKNLEQIKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9E7</accession>
    <name>A0A0C1K9E7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HE00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385098.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75802">
        <property type="protein sequence ID" value="KIC75802"/>
        <property type="gene ID" value="DB41_HE00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="366" mass="40782" checksum="2AED664586E244D1" modified="2015-04-01" version="1">MDAGWNSPRTEQKPELTNKPTQLEGKEGKGQAHGRGSIDLSSTNQRASHIAQSALPVTEQSDSQNVKSKRSRWDQLPSSHTQTKGDQLPRLTKKSRQDVSPQPVGAKEVGARAEEVATKALSLHLASSIRFSHPYVSPVMDNGKITIDAFKENVVKKNLWDPALPIEVVRMPDRGLTSFDNRRLTALRQAAEEKIGEGDTASLEEIKFYVKILEHGSEANPDLLRRIDSMWGQHVQKNDRTNVEKEIAAAAVAYRMKEGSIGYAMITRVHQYDSLIARTAKVGQQNVLGYSELPEIKDAEHYKEKGKYRSMERRIGAGPSPAAAHKTSDLRNPPRPSQQAIKKKEIEDAAYLAELLKEMEEEHKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9Y4</accession>
    <name>A0A0C1K9Y4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GU00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75952">
        <property type="protein sequence ID" value="KIC75952"/>
        <property type="gene ID" value="DB41_GU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6735" checksum="136CEE72E2B95DBA" modified="2015-04-01" version="1" fragment="single">KRWRIEEYHKSIKQNASLEKSPTKIARSQRNRIFSSLIAYCKLEFLKIKTLLNHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAH4</accession>
    <name>A0A0C1KAH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GN00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384777.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76092">
        <property type="protein sequence ID" value="KIC76092"/>
        <property type="gene ID" value="DB41_GN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="214" mass="25420" checksum="941973F4493BCA27" modified="2015-04-01" version="1">MAERQKDKTLLWTEQEYLDNFQAIKDSSLGKVITNPFRLKITVEVLPIIVKKYLSECPDLELESIFFGRKKFVISKELFDVFACVTAYRSSVKTEGGSYIAPEKYLTYSVQLALKMGSCNRTFIPWPPESFVGIKEQERNDIRNSFKDFFEPAKSRERFYKECLIQRNEGWSFIHKDYQEYLEYLGEKSPAELEEFMNRIVKEYKFKELFSHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB21</accession>
    <name>A0A0C1KB21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Insertion sequence IS408 putative ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GJ00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000095">
        <property type="protein sequence ID" value="KIC76322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76322">
        <property type="protein sequence ID" value="KIC76322"/>
        <property type="gene ID" value="DB41_GJ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="15074" checksum="E51AAEF0BFD0E801" modified="2015-04-01" version="1" fragment="single">GYEVLFYRTYQLFYWISMGHGDGSYRKRLQQVIKVPLLILDDFGLQSLSEASQMDLYEVICERYEKAATIITSNREFGEWQEIFANPLIGSAALDRLIHRATKLVIEGKSYRMEQFHKRSKQNKETEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB82</accession>
    <name>A0A0C1KB82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative RNase BN, tRNA processing enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rbn</name>
        <name evidence="4" type="ORF">DB41_GG00050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243879.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76397">
        <property type="protein sequence ID" value="KIC76397"/>
        <property type="gene ID" value="DB41_GG00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="412" mass="47146" checksum="F569AA6EAE57E398" modified="2015-04-01" version="1">MKRIWKLFCHTVKGFYEDDCNARAAALTYFTLMSIVPVLAVILGLARGFGFAPFLEEVIKEQLSKQPDIANYTIDFAYSLLEETSSTLIAGVGVVLLLWTVYNILGNVEEALNDIWKIPRARSWIRKVTDYIAAIIICPLFFVVSSSLTIYLKTHIVEISGKAVFFEYLFIHFFPFLITWMLFTFLYFFLPNRKISFKYGMLGVLVGGTAYQLIQTFYINIQLKLSSYGAIYGSFAALPLFLIWLNLSWMIILAGAELAYQAEIMAWNYAPTRKGSPPILTCRRVLALMIIYSCIRNFCEGKTPYTIHQISDKFGVAKIKLAEIIEILTHYKILSTTDYYSDGEIYYQPARDVNTITLKNVADIFPAIEKEVVCIYRNPSVSYFEELLAKYDKKTTEMQENLPLSAINLQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBJ9</accession>
    <name>A0A0C1KBJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_FU00020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384329.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76517">
        <property type="protein sequence ID" value="KIC76517"/>
        <property type="gene ID" value="DB41_FU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="35"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="602"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="644"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="728"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="896"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="938"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="980"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1064"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1190"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1232"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1274"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1316"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1400"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1442"/>
            <end position="1475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1501" mass="168995" checksum="93327C07A9AE65B8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBL7</accession>
    <name>A0A0C1KBL7_9BACT</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000080">
        <property type="protein sequence ID" value="KIC76532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76532">
        <property type="protein sequence ID" value="KIC76532"/>
        <property type="gene ID" value="DB41_FT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="170"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="293" mass="33931" checksum="A6BB64EDD1F034B7" modified="2015-04-01" version="1">MQISTLAKLYIFIDRHADYVPLASTVTSLIDIFQKVAIQTFKPIENPSSHYYYSYLNKKSFKRCIILLIPVLGNIVVTILDCVQQRCKDPSYERRNSHKNSMHAKNSSTKNCQKIKNKNLTSLPINSAKETVLFSNQIPAPVISKLADQLEMFVDNEGILDSNYCHQQTCDKLNRIFDKQLHKIRELEKEAYSILKTSNDSEQYSLCLSSAEKEVESIKNIISALYRKKASNTTHHKELKKNRKSPSEYACMYSSRKKYGLKKRCGNDAEYKYYSSPTNLFFFNLRNFPRTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC57</accession>
    <name>A0A0C1KC57_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Neochlamydia sp. TUME1</name>
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            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
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                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76682">
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        <property type="gene ID" value="DB41_FB00240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.635"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="304" mass="34325" checksum="16B0E123F7C8CC51" modified="2015-04-01" version="1">MNPSSSANIEHLPNELLIPILKACASPSLFSVCGRWHHLLANEVMPSLYKQIGKVHVPQGDVNKQALVLDRIYKLEEELSKTAKVNAIFRQIFTLASSLSPLELELKDKPKEKKYFTLANYSSYLVNINRLLMWKKIPGGEGFLDQEKIKYLPLQRKGELFKEWIVRYGKDMTRLVLAESGLASLPAEIGQLSQLQLLRLNQNQLTALSPEIGQLSQLQWLSLRSNQLTALPAEIGQLSQLQTLDLSQNQLTALPAEIGQLSQLQTLDLSNNQLASLPEEIGQLWQLQELRSCQKPAHQPTYRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC64</accession>
    <name>A0A0C1KC64_9BACT</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Parachlamydiaceae</taxon>
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            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243819.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76692">
        <property type="protein sequence ID" value="KIC76692"/>
        <property type="gene ID" value="DB41_EY00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="226" mass="26247" checksum="8DED15CB9ACCF52E" modified="2015-04-01" version="1">MNKLAKIPVEEWVNAYLSHQEYKRSTTLCAIMTSFGSDKGDKRHNYTTLYAKLFGPWRHNNINLFELGIGTNYSDIPYNMGKEGIPGASLHGWALFFPKAHIFGADIDQRILFQTPTIKTYYCDQRQKSSIHHLFSNTELNNLQFDIMLEDGLHEFEANLNFLQHSIHKLKEGGIYIIEDLTAHSRVAFIKLIPYLRKEYQLKYIEVIIIPSKLNHFDNALLVIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCA5</accession>
    <name>A0A0C1KCA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="8">1.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">queG</name>
        <name evidence="8" type="ORF">DB41_ET00020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383937.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76732">
        <property type="protein sequence ID" value="KIC76732"/>
        <property type="gene ID" value="DB41_ET00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.554"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="306" mass="34340" checksum="ECC5D3BE889B1356" modified="2015-04-01" version="1">MTLSFDEIKVKALELGWDDVGITPANVRPEDIQAYKEWLAEGKHADLAYMEKEIRCYPQQYFPQAKTALIFLSYYKQPKENLLAGQGLIASYARGRDYHHVHRKRLKKFIQWLEERVGEQGIAKGFSDSSPLLEKALAVQAGLGWFGKNTLLIHRRFGTYTLISGILTSLEIPGAVISLRLPRCGSCTRCIDACPTQALTSPYKLDAAKCLSYHLIESKKPIPLEIQQKNPGYIFGCDICQDACPHNQRTLPSLTAAFSPASGNGTYLDLEKLEECEKNPEKLFGTPLQRRGITGLKYTAETLKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCB0</accession>
    <name>A0A0C1KCB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_ET00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76737">
        <property type="protein sequence ID" value="KIC76737"/>
        <property type="gene ID" value="DB41_ET00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.559"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="67"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="297" mass="33786" checksum="89ACC8E671019DD5" modified="2015-04-01" version="1">MDLHTLFIKKEINMVYSRSNEHENHITIQGVEIALGFPDQFNFQWIGQKDVLDQLLAAWLVIDERDIPLNPRLIGKPGVGKTTLAYAAAKKLNKEVYIFQCTMDTRPEDLLISPVIDKAGGIRYVASALVTAMLRGGVCILDEANRMSEKSWASLAPLLDTRRYIESIVAGLKVSADPGFRICITMNDDTSTFEIPEYIHSRLQPQIYLDFPEAEEEKRILKENLPFIDEYIVEYVINFLQKAHTNAENYTIRDGINIARYAAKRLKTLENSKINIDNLLRQAVLMTLGDEALTHLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCN7</accession>
    <name>A0A0C1KCN7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">DB41_EG00070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76842">
        <property type="protein sequence ID" value="KIC76842"/>
        <property type="gene ID" value="DB41_EG00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.464"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="61"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="309" mass="35256" checksum="6EA505583CB50C2B" modified="2015-04-01" version="1">MLATYKANRSAYLENLLSFNREGKFKIMPIYRPSELHHFLNKLGVSPKKGLSQNFLIDGNITRKIVAYAALSPHDLVVEIGPGPGCLSEEIIKHGSQLLTIEKDPVMAQALQRLQTESNRLEIFCEDVLEFPLGEKLLEILKPGQKAIIVGNLPYHLTTPILIQLVKLYPYVSKVVVMVQEEVARRFTAQPGTSEYSSFTVFLNYYSTPRYAFMVRRACFHPIPNVDSAVVTLDLHQPPFVANEEDFFKMTRTAFGQRRKMMRTSLKELYCSQAVSQALLQIGRDVKSRPEELSLEDFMHLYRKLNNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDG4</accession>
    <name>A0A0C1KDG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DI00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77047">
        <property type="protein sequence ID" value="KIC77047"/>
        <property type="gene ID" value="DB41_DI00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="7885" checksum="3DB28D9398EE88C2" modified="2015-04-01" version="1">MASKFEAILIQQFATDLCFYIATGGSTQPLDFYTDYLIRKALLFLICPDVDAAGAKFIRKIKGNYKQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDT5</accession>
    <name>A0A0C1KDT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfite reductase [NADPH] flavoprotein alpha-component</fullName>
            <ecNumber evidence="6">1.8.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cysJ</name>
        <name evidence="6" type="ORF">DB41_CX00030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383295.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77137">
        <property type="protein sequence ID" value="KIC77137"/>
        <property type="gene ID" value="DB41_CX00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.156"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="383" mass="43793" checksum="1E5272674020B189" modified="2015-04-01" version="1">MESLIYNRHHPFLATIKERYNLTREESIKNTQHVVLDIKGSGLTYKVGDSLGIFPINPQDIVNKTLLAMRAQGSELIISKHTGKSMSLRDFLTTKANVTDLSKKFLSIIAQGQPNQKKRETLEAVLAEGAQEKFKAYLQSHELWDILEENNEVVFSLQELCNMLMPLLPRLYSISSSMSAVGEEVHLTVGVLKYHTNGYQRVGVCTHYLCETVPLHQPVVPIYIQPHHGFTLPSHSDTPIIMIGPGTGVAPFRAFMQERMAKEAQGKNWLFFGECNRATDFYYADYWTSLERQGKLRLDVAFSRDQQEKIYVQHRMLMQGADLYRWINEGAYIYVCGDAARMAKDVESALHEIIQVHGKKSEAEAKALVKHLRNEKRYLRDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDU0</accession>
    <name>A0A0C1KDU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CX00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77142">
        <property type="protein sequence ID" value="KIC77142"/>
        <property type="gene ID" value="DB41_CX00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4526" checksum="F64DAB19323BF792" modified="2015-04-01" version="1">MDKSGINAYLQRQHARSLIGEKIYGAIAGRSFARESFIAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDY5</accession>
    <name>A0A0C1KDY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CT00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77187">
        <property type="protein sequence ID" value="KIC77187"/>
        <property type="gene ID" value="DB41_CT00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="316" mass="37419" checksum="FFCB265A06DA46DA" modified="2015-04-01" version="1">MCKTLFKNTRNKFLNKWVRVLLISLGLFGLTRLYFKMTDDFRLSNISYNMPYRHEWEVPSLSKEEQQQLDNILDQKFYYVGKGAQSYAFKSADDKYILKFFKFKHLKPSVFISLIPPIGPLKAYKDKQRERKHRLLNSVFDGYRLAYNIHAHEAGLIYIHLNKSVNLHKIVAVKDKIGIERQVDLDQVPFILQEKANTTRAEMMTLMGAQDMSGVKKRIQQIFDLYLLEYNKGIYDRDHGVMHNTGFVQDRAIHLDVGKLTKDERMKNSAYSQPDFLQVVHKLNAWFKLNYPEYHSTINVYMEQQMQKMFEEIPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H0N1</accession>
    <name>A0A0C1H0N1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BO00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000235">
        <property type="protein sequence ID" value="KIC71309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71309">
        <property type="protein sequence ID" value="KIC71309"/>
        <property type="gene ID" value="DB41_BO00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6281" checksum="2C033D50AB389125" modified="2015-04-01" version="1">MIRSLWTGWEQLKGNGLGRVDPLAYVLRTGMDDDAVNALAMTVISVSLGWVEAVSMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H308</accession>
    <name>A0A0C1H308_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AC00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71984">
        <property type="protein sequence ID" value="KIC71984"/>
        <property type="gene ID" value="DB41_AC00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5369" checksum="7FAA100956E8E6AE" modified="2015-04-01" version="1">MSELISKQEGLLQKDYAIYRGPNSHTRIRGVAINTLLHIIHLLDIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H363</accession>
    <name>A0A0C1H363_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AA00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386555.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72024">
        <property type="protein sequence ID" value="KIC72024"/>
        <property type="gene ID" value="DB41_AA00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="273" mass="31129" checksum="D828CCB8A8C851DD" modified="2015-04-01" version="1">MVKFFKPLIVESASQDPYLQSSKYEKIRAKTVRYQGTTYEKITYKELNVHSLGWRICYGVLAALATLSLIPLALDYKGVKKLWLRASTGTRDKVIWVAQKAINPLSDNLPNLGKAKNQETNFLKDVRKREAALIEGRWTGKSTKKEATAKAQAAVKIKDSGILEDVRKREQASIEAKLPKQSDKPISAGNWGKDFISRVRRNQKTQRELKMAREVNTTPQAKVEEATLPAKRGTKKSRKKSFSVRFSQERKREYNKEAPPIEVDHQTSIKRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3T0</accession>
    <name>A0A0C1H3T0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KR00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386520.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72189">
        <property type="protein sequence ID" value="KIC72189"/>
        <property type="gene ID" value="DB41_KR00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2042"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="562" mass="63246" checksum="8D1ABD1B05D3EC0B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4M9</accession>
    <name>A0A0C1H4M9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386381.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72479">
        <property type="protein sequence ID" value="KIC72479"/>
        <property type="gene ID" value="DB41_KK00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="7933" checksum="74CE8ACBFE444401" modified="2015-04-01" version="1">MHFISLGSNNFSACLFFKNNIKKLKKQVKTIRILINEKQLTDNLPRFFQIDSRKGRIPSKHLGAATGSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H502</accession>
    <name>A0A0C1H502_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">der</name>
        <name evidence="11" type="ORF">DB41_KI00080</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72564">
        <property type="protein sequence ID" value="KIC72564"/>
        <property type="gene ID" value="DB41_KI00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1900"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="17"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="190"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="196"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="243"/>
            <end position="247"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="308"/>
            <end position="311"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC72564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="486" mass="55570" checksum="FC605561830259D9" modified="2015-04-01" version="1">MICQLNIKIDRVMTHLPKLAIVGRPNVGKSALFNRICKKKIAIVDEAEGITRDRLYSQAEFFGRAFEVIDTGGMDYHSHADFNEHILRQAEVAIEEADTIVMVVDAHLGITKLDKEISKILLKTKKPVCLAVNKIDNGAQEYLLHEFHSLGIKKMISVSAAQGWHMAELLEEAFEDLEQDDLQAEEDLATKVAIVGRPNVGKSSLINFLLDEERCIVSPIPGTTRDSIDVSVTHQEDHFRLIDTAGIRRKHAEHEVVDKFAAIRTERAIERADICVLMLDAQQGMTVQDKKIANKIEESGKGCILVFNKWDLVKGFRMEHCLKDINDEVSFLSHCPKIFMSATTGRNVEKLFEEIKSVQEHSLKRIPTHQLNKFIESALQKNHPPMIGGKRLRIYYMAQVDVQPPKFILFVNYPNLMSESYKKYLYNQFRETYGFVGVPLELYVKGKKKTTFSERKAKSQLQPQEKYQEDDEIVQAYEDFEEEENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5A6</accession>
    <name>A0A0C1H5A6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein lap1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">let-413_3</name>
        <name evidence="3" type="ORF">DB41_KF00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000187">
        <property type="protein sequence ID" value="KIC72639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244045.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000187.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72639">
        <property type="protein sequence ID" value="KIC72639"/>
        <property type="gene ID" value="DB41_KF00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1886"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="585" mass="66384" checksum="E95B43F396B42CEE" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6B4</accession>
    <name>A0A0C1H6B4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HSDR_N_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JV00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386236.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000178.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73014">
        <property type="protein sequence ID" value="KIC73014"/>
        <property type="gene ID" value="DB41_JV00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSDR_N_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="152" mass="17726" checksum="7924AD511B1413C8" modified="2015-04-01" version="1">MEKEEKQKIYCAIRKNWLIATPEELVRQQAIQLLIQHLGFPRSCIAVEKELQSLPHLKIFTSLLPERRADIICYLPKENSLHPLLLIECKAVPISSKEILQVIGYNRFIKASFIALINQTEHKLGWFDPELSDYQFVNYLPFYSDLVNSLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6U7</accession>
    <name>A0A0C1H6U7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JN00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000170">
        <property type="protein sequence ID" value="KIC73194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386182.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000170.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73194">
        <property type="protein sequence ID" value="KIC73194"/>
        <property type="gene ID" value="DB41_JN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="38"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="DUF294" evidence="1">
        <location>
            <begin position="193"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="525" mass="60394" checksum="D7A86BE7295B0184" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H976</accession>
    <name>A0A0C1H976_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IW00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000154">
        <property type="protein sequence ID" value="KIC73904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73904">
        <property type="protein sequence ID" value="KIC73904"/>
        <property type="gene ID" value="DB41_IW00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="157" mass="17999" checksum="920EAD93159FFEE1" modified="2015-04-01" version="1" fragment="single">GEKKIEFTMTPRPVEKCWNKKSILTISSYDGKRLAVGLNTSLIITYNPDDGNFLTEANIGLLAPVRFLVLDDNYFLASHFHPEFKSFDLYQHTPAIKCCGTIFPFLPDPYPWVNSYHIHASYDGRELAFCDEHGWLHLWDFAHLQGKERILVAPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAV9</accession>
    <name>A0A0C1HAV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltrans_SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_IJ00050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74534">
        <property type="protein sequence ID" value="KIC74534"/>
        <property type="gene ID" value="DB41_IJ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1584"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="66"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="282" mass="31936" checksum="7C82FEA9C7CB5C38" modified="2015-04-01" version="1">MKNCMNTYSLIDSGNGYKLEQFGPYTISRPCSQAVWEPRLSQESWDHAHAFFSREGQNKWTFRKEKLPDMWHIKVADIAFKISPTDFGHLGIFPEQRAFWKWIQSTPIKGKRVLNLFAYSGGSTLAAAQAGAEVCHLDASKGMVAWARENAALNHLEKAPIRWIIDDVFKFLGRELRRGSRYDAIILDPPSFGRGANGEVFKIEEEINKLLRSCRELLTPKPLFILFSCHTPGFSPLVMKHLLHQNLDGLSGTIDEGEMLLEGSTETFPIPSGTFARWQYAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAW3</accession>
    <name>A0A0C1HAW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243987.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74539">
        <property type="protein sequence ID" value="KIC74539"/>
        <property type="gene ID" value="DB41_IJ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1589"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019626">
        <property type="entry name" value="Stress-induced_KGG_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10685">
        <property type="entry name" value="KGG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="445" mass="49756" checksum="89313E49FC227632" modified="2015-04-01" version="1">MPTRKSSGATRQEAGQKGAEARSGRSSSDRGGRGGRGHQEPMSRQEAGQRGGRAVSEKYGPEFYQEIGHKGGQAVASKYGPDFYRDIGHRGGEKVASERGHEFYQDIGHRGGQRVAEEYGPDFYREIGRKGGRAVASKYGPDFYREIGHKGGEKVASERGHEFYQDIGHKGGQRVAEEYGPDFYREIGRKGGRAVSSKYGPDFYREIGHKGGEKVASERGPEFYHDIGHKGGQRVAEEYGPDFYREIGRKGGRAVSSKYGPEYYREIGSKGGHARGGHEEGHESDEDYEGEDEGYRGHRGESHGRYQRAGYHSEEPHHGYESDEDYEDEDEGYRSHGGYQSGRHGEESHQGYESDEDYEDEDEGHRSQRGASHGYSQRSQHQGAEAHHDESDEEEGDEEYSHQGSGKMSRQEAGRKGGLATASHRSREEYREMGRKGGLARRENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB72</accession>
    <name>A0A0C1HB72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386571.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72043">
        <property type="protein sequence ID" value="KIC72043"/>
        <property type="gene ID" value="DB41_AA00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="273" mass="31238" checksum="5BBA3956F7024D93" modified="2015-04-01" version="1">MNTHSLSPTFSHLPNFLSIGSSRESQLKETTTYHSKINATVQQSLKPLKLTNSSLSSLSMKISDSPLATALLSKLQEINLLQQRYYLSSKNTWNNIPCFSSFIMPLLNAKNLLIRPATPSEAKDYYFTAPTIRTHQMIVITSGSDTTTLLGAIEYWHNSETHKCGINTLKIHKLTKESYLIKKLLFLYIIFAAKEHRCQEVFICFEDEGEAHLYMPYGFLPDDCEDEEKEEWKSLSLEKQSEKIMTEEGGHCCLKLTEENMVLIKEKLDELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBL6</accession>
    <name>A0A0C1HBL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KR00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386514.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72183">
        <property type="protein sequence ID" value="KIC72183"/>
        <property type="gene ID" value="DB41_KR00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="150" mass="16774" checksum="56D373ED7E717FC8" modified="2015-04-01" version="1">MDLENEFLLSYQVLKPFREDFGQNVPSVYKQANWKGRVYCFIQLISSPITALFKVGRKVGAVASLVATVASLSLYLITKCLGKIWKRKPIKRQDVLNEAANIKKLTLYALDLSIALALSPIGLLASRVRYLIGIIYPPLAFSPSFLVIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCI5</accession>
    <name>A0A0C1HCI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KK00290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72503">
        <property type="protein sequence ID" value="KIC72503"/>
        <property type="gene ID" value="DB41_KK00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6397" checksum="A334BA5DB11B355B" modified="2015-04-01" version="1" fragment="single">PAEIGQLSQLTRLYLNQNQLTALPAEIGQLSQLIELELAENPLKDIPEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD77</accession>
    <name>A0A0C1HD77_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="15" type="ORF">DB41_KD00180</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386300.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72718">
        <property type="protein sequence ID" value="KIC72718"/>
        <property type="gene ID" value="DB41_KD00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1876"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="13">
        <location>
            <begin position="9"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="14">
        <location>
            <begin position="401"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC72718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="631" mass="69748" checksum="A0DAE270625AE7CD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEJ4</accession>
    <name>A0A0C1HEJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JS00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000175">
        <property type="protein sequence ID" value="KIC73123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73123">
        <property type="protein sequence ID" value="KIC73123"/>
        <property type="gene ID" value="DB41_JS00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5056" checksum="A2371477748DF309" modified="2015-04-01" version="1">MIENSLHHAMDMFFKEDALLSDVGFSAKKHGFNQALSCQHNKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFX8</accession>
    <name>A0A0C1HFX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ABC transporter ATP-binding protein YbiT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ybiT_2</name>
        <name evidence="6" type="ORF">DB41_GK00030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384662.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76289">
        <property type="protein sequence ID" value="KIC76289"/>
        <property type="gene ID" value="DB41_GK00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="324"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="559"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="356"/>
            <end position="363"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="636" mass="72325" checksum="C1CDF1DCE4C4972A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGA7</accession>
    <name>A0A0C1HGA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gcp</name>
        <name evidence="6" type="synonym">tsaD</name>
        <name evidence="8" type="ORF">DB41_GG00120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76404">
        <property type="protein sequence ID" value="KIC76404"/>
        <property type="gene ID" value="DB41_GG00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.896"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="25"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="136"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="328" mass="35434" checksum="24E058974065E866" modified="2015-04-01" version="1">MLMLVLGIETTCDETACAVVKDGREILSNVVFSQIDLHQKFGGVVPELACRKHVDVLFPVIDQALQEANCKLEDIDLFSVAYGPGLIGAVLIGLNAIKTIALCMNKPYVGVNHVEAHLYAALMSNPHAEFPCLGIVLSGGHTSLIYMHEIGKYELIGQTVDDAIGEAFDKVAKIMGLPYPGGPPIEVLAEKGSSLRYPLKAGTVKGKPFDFSFSGLKTGVLYTYNLTSDKSDLAASFQYAAFADILKKTIQAAEKYNCKTLVFGGGVTNNKALRKMFIEKGSHYTQYWPSLGLSLDNAAMIAGLAYHIYKHKGKGDDLTLEAATSISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGH3</accession>
    <name>A0A0C1HGH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RNA-binding protein RbpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rbpA</name>
        <name evidence="3" type="ORF">DB41_GC00260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384536.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76459">
        <property type="protein sequence ID" value="KIC76459"/>
        <property type="gene ID" value="DB41_GC00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="116" mass="12908" checksum="60845C47E5EA076F" modified="2015-04-01" version="1">MKKIFVGNLSWKASEETLKPLFEAFGTVVSIKIIKDQYTGKSKGFGFVEMEADDEAAKCIHELNEKPFLERNLHLSPAQERQPGAGGGRDSRSPRGNGGDSYSRGGQRSNRDRNYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGP9</accession>
    <name>A0A0C1HGP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FX00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384399.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76509">
        <property type="protein sequence ID" value="KIC76509"/>
        <property type="gene ID" value="DB41_FX00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="9982" checksum="070E19AC00C83D64" modified="2015-04-01" version="1">MLGYIVGDSALYTPTTSQVFKREQSLFAARVPVQIKEAKELIVEAPYDKTVEIRAFKATSCYAGVELKMGSHPQPSSLSKRIPYFSQALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHH1</accession>
    <name>A0A0C1HHH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Insertion element IS402 uncharacterized 16.2 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EO00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76764">
        <property type="protein sequence ID" value="KIC76764"/>
        <property type="gene ID" value="DB41_EO00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.548"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="124" mass="14889" checksum="27EBFF79596EFA32" modified="2015-04-01" version="1">MSNTYPSHLSDREWEAIKIYFEVDYSKGGRPFKHTKRELLEAIFYVLRTGCQWHYLPKDFPHWKTVYTYFKRWKGAHLFEKINHHLRKKLRVIMGRNLDPSAAIVDSQSVKTVKRGGAHRLRWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHJ0</accession>
    <name>A0A0C1HHJ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">xerC</name>
        <name evidence="7" type="ORF">DB41_EJ00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383857.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76779">
        <property type="protein sequence ID" value="KIC76779"/>
        <property type="gene ID" value="DB41_EJ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.524"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0229">DNA integration</keyword>
    <keyword evidence="2 3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="134"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="3">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="331" mass="38039" checksum="3090C8B44ECC4A70" modified="2015-04-01" version="1">MFISTAQKFLKHLKTIRNASEHTVRNYAIDLNAFKIYIETYHLPPKASQEVAPKIHHNMVDKYSTAYDALIPLSMIDRKTIRGFLATLTQNGINKKTIVRRLSSIRAFFKYAFSHKFISINPTEELDTPKIEKKLPTSLSYDQVLKIFAAPDLSTFLGFRDRVIMELFYSSGLRVSELASLNRRDFDYQNLLVRLKGKGKKERVIPITKNAAQWIQKYLEHPERHACTDGHREQVDSQAIFLNKLGTRLTTRSIDRTFDNYIKNSGLAGKITPHTIRHTIATHWLENGMDLKTIQVLLGHTSLSTTTIYTQVSPKLKKKVYHQSHPRANAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHP3</accession>
    <name>A0A0C1HHP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 9">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rplV</name>
        <name evidence="10" type="ORF">DB41_EH00180</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="5">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6 9">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383798.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76834">
        <property type="protein sequence ID" value="KIC76834"/>
        <property type="gene ID" value="DB41_EH00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.483"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="113" mass="12644" checksum="5B621B86D7106BC5" modified="2015-04-01" version="1">MNRAKAISKYIRISPRKARLAAGLIRGLPVPQANLQLLYSNLKAGRLLKKTLDSAVANAETQLDIRREDLKVLEVRIDEGPRLKRAKPKNKGGRHPILKRTSHFTIIVSSGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHV4</accession>
    <name>A0A0C1HHV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative cell shape (Rod)-determining protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rodA</name>
        <name evidence="7" type="ORF">DB41_DT00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383644.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76909">
        <property type="protein sequence ID" value="KIC76909"/>
        <property type="gene ID" value="DB41_DT00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.392"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="378" mass="42774" checksum="0B09FA34374A8E39" modified="2015-04-01" version="1">MWNYQYLSRIDFRIIPVILGLMVMSLLVISAYSLEGSAEITEERLITPMVRQQIQWFMIGGFVFIFFAGFDYNKLRELAWILYALVILSLVGLFFTDSIARVNRWYRLPFINISFQPSEYAKLIVVITLSWFLERTKADSHSFRTAFFSMIIVGIPFILILKQPDLGTALVLFPITLVMFYFGDIHPKIIKAMTFVASIVLIIVALIFLGVLPHEKLRPYASLILKDYQFDRLNPYTHHQKSASIAIGIGGLTGVGFRKSEYTSGGWLPAAYTDSVFPAFGEEFGFIGLLLMLMLFYALIYFSFQVSVVAKDHFGRLLSAGITVYLAMHILVNIGMMSGFLPITGVPLVLVTYGGSSTLSTMMALGILQSIYSRRFMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI63</accession>
    <name>A0A0C1HI63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative bifunctional transcriptional activator/DNA repair enzyme AlkA</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
            <ecNumber evidence="10">3.2.2.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">alkA</name>
        <name evidence="10" type="ORF">DB41_DN00100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EC" id="3.2.2.21" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76989">
        <property type="protein sequence ID" value="KIC76989"/>
        <property type="gene ID" value="DB41_DN00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.300"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052822">
        <property type="term" value="F:DNA-3-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052821">
        <property type="term" value="F:DNA-7-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010316">
        <property type="entry name" value="AlkA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037046">
        <property type="entry name" value="AlkA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06029">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01009">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="9">
        <location>
            <begin position="87"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="473" mass="54300" checksum="F4AB613A234A3F6E" modified="2015-04-01" version="1">MVMNEEDIFYKAFLSRDSRFDGKFYVGVKTTKIYCRPICPARPKRQNVEFFLEALSAEKAGYRPCLRCHPPSSTPSSAYSGKSAVVSRVLRVLTNQGMGDKGEDYFAEQFGLSARHLRRLFREEVGLTPQKIWDNNRLNFALKLLAETKLSITRIALEAGFSSLRRFNDAFKKCYKQPPSSMRKKNLSHSSHENIILKLTYHPPLDWPHLINHFKNHFIPYIESISENSYERVFKIGDSIGTLSVEADSRYPYLKLRIACHDTKVLFEVANRVRKMFDLDSDPLLIANQFASHLPLSLLWKQWPGLRLANGWDPYETAICAILGQGITMKYASQLIGHLVLYYGEKIFHPVTQEERYLFPLPEILAKASLHEIKTTQIRKAAIRMLSQKILQQEISLSPAQAPEEFKKSLLGIQGIGPWTAEYISLRALADTDAFPATDLILKRALRLNPSLDLSCIRPWRGYAAVYLWKKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIA7</accession>
    <name>A0A0C1HIA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383527.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77014">
        <property type="protein sequence ID" value="KIC77014"/>
        <property type="gene ID" value="DB41_DN00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="119" mass="13759" checksum="EF1422712FCCE1C3" modified="2015-04-01" version="1">MSVPTYSAVYYVLESEQGGINPLAIRPQIKNQGKVIEWEDTGHGFWSKLKTSPSTRDEMISYCPTEIIVPISDTHQLKLVYLTKEIFDKHISKNAAMQPKFETTQELQNYYLNTNFYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HID3</accession>
    <name>A0A0C1HID3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DL00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77029">
        <property type="protein sequence ID" value="KIC77029"/>
        <property type="gene ID" value="DB41_DL00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4506" checksum="70E1877A74798589" modified="2015-04-01" version="1">MRRPGSFERSLAAIAEDRLPKRRCIALKEAWEETFSLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIQ2</accession>
    <name>A0A0C1HIQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative DNA polymerase III epsilon chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dnaQ_2</name>
        <name evidence="2" type="ORF">DB41_CZ00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383326.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77129">
        <property type="protein sequence ID" value="KIC77129"/>
        <property type="gene ID" value="DB41_CZ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.184"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024530">
        <property type="entry name" value="QSregVF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12843">
        <property type="entry name" value="QSregVF_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="249" mass="28487" checksum="B720091E6B921477" modified="2015-04-01" version="1">MKPLHTQTFVCLDCETTGLDPQRDRIIEVAAVRFTVEQVLAQCESLIDPECEIPETSIAIHHIVPQMVQGKPKINEYLPEFLKFVSNDILVGHGIKFDMEVIAASAARANIPCHIQHNRYIDTLRLARHYGESPINSLEQLRKHFNIQEEGAHRAMNDVVVNMDVFKYLVKPYKTVEQVFDLLSRPVSMKIMPLGKHKGRPITEVPLQFLLWAANKDFDQDLLFSIRSEIKRRKKGNTFGQAANPFSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIS4</accession>
    <name>A0A0C1HIS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CV00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383245.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77164">
        <property type="protein sequence ID" value="KIC77164"/>
        <property type="gene ID" value="DB41_CV00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1029" mass="117666" checksum="062079C13496FE82" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKC2</accession>
    <name>A0A0C1HKC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ubiquinol oxidase subunit 1</fullName>
            <ecNumber evidence="8">1.10.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cyoB</name>
        <name evidence="8" type="ORF">DB41_IB00710</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.-" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385755.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74938">
        <property type="protein sequence ID" value="KIC74938"/>
        <property type="gene ID" value="DB41_IB00710"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1506"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014207">
        <property type="entry name" value="Cyt_c_ubiqinol_oxidase_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02843">
        <property type="entry name" value="CyoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="7">
        <location>
            <begin position="38"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC74938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="654" mass="73404" checksum="679B8C713803C338" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKG7</accession>
    <name>A0A0C1HKG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IB01060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385804.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74973">
        <property type="protein sequence ID" value="KIC74973"/>
        <property type="gene ID" value="DB41_IB01060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133245" description="BON domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="3">
        <location>
            <begin position="108"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="21107" checksum="B7E2CEB587BA6BB0" modified="2015-04-01" version="1">MKISLSIFSYTCAGILLATMSSAYGQCTEEDCPIFNSYFDHPASSPSSYSLQTSQESRAFSSQNSSKTESKRKNGGESRVQQGFNREGSPNQREINSKQISSYQNKGSDSVIYYQIEETLKNNRLKKNYPLVNIRFYQGMATLSGTVETEDDRQQVESRVRAIQGVADINDQLQVESSTPHNQGSKPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN15</accession>
    <name>A0A0C1HN15_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">recF</name>
        <name evidence="8" type="ORF">DB41_HH00260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RecF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385229.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75733">
        <property type="protein sequence ID" value="KIC75733"/>
        <property type="gene ID" value="DB41_HH00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1224"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00617">
        <property type="entry name" value="RECF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="SMC_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="344" mass="39649" checksum="6264136C248C2075" modified="2015-04-01" version="1">MSSGLFLQKLYLRYFRRYEEATFDFTPAINTIVGPNAYGKTTILEAIQLLINGRSFRTQQISDMIQYGQKYFHIEACFIKQGIAQTLKILYDGSERKIIHNSTAFSSVANLLGILQGVVLTPDSTSLIKGSPLLRRHFLDLQIAQIDPLYVHYLTRYIGAMRQRNVLLKKNEMLAIQTWEQEMAGAAAYVTLQREQTIADLQKWGNGLYGMLTAETAPLSLEYKNSSRQIKDMQLLRQHYLQQWDKLRVREKEVGMTLYGPHRDDLLIKIGDREVRLFASEGQQRSCVMALRLAEWQRLRELSQELPLMLIDDVGVSLDTTRRQKLLIHLKTLGQVFITSTEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNA1</accession>
    <name>A0A0C1HNA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385100.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75803">
        <property type="protein sequence ID" value="KIC75803"/>
        <property type="gene ID" value="DB41_HE00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7248" checksum="0FA7A624888D6A1D" modified="2015-04-01" version="1">MENLKAALAPDLSKKFKGKSLYTHQDKIRNSLCVILIADSRWYDLFKGPNWGWRREIKIGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNZ2</accession>
    <name>A0A0C1HNZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative 3-methyladenine DNA glycosylase</fullName>
            <ecNumber evidence="5">3.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_GR00100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384849.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75998">
        <property type="protein sequence ID" value="KIC75998"/>
        <property type="gene ID" value="DB41_GR00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1006"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00540">
        <property type="entry name" value="AAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00527">
        <property type="entry name" value="3MGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003180">
        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="PTHR10429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00567">
        <property type="entry name" value="3mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="194" mass="21814" checksum="004119B0FCCE653F" modified="2015-04-01" version="1">MEKLSLDFYLRDDVLQISQELLGKVLMTYINGVYTGGIITETEAYRGPEDRASHAYGGRRTKRNEVMYHAGGHAYVYRIYGIHAMFNIVTNSIEIPHAILIRAIKPIIGVEQMIKRRNKTKNKASLTGGPGTLAQALGIDTIHNGLLLTGPLIWLEDHHICCEKKNLVIGPRVGIDYAGEHAQLPWRFIYALEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQH4</accession>
    <name>A0A0C1HQH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_GC00050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384498.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76438">
        <property type="protein sequence ID" value="KIC76438"/>
        <property type="gene ID" value="DB41_GC00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.832"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="472" mass="53302" checksum="AC03EB77CE99E2AC" modified="2015-04-01" version="1">MFDPTSLKVRKQIMGLLLNRWGLTCMGILTFQQILEASSTLWLVKLVETIASHQNFLPYMLLYLTSLALPYIPGCIALIVKTHWKQEAQRHFIHAFVTSNRNNIGEWNNKAIKEEKLSILTSEGPLALQDLIDYVWELSGYVLSVILNILALSIVVEPLFALAYSISVLCVIAIMKGQRRTQRQLTRKALTARVDLSQQLLAAWDNVLLGNGYNFKLWDEKTSQRLKRCLQRNIDLERFDQVLAIFVALITSIPSLGVVIYSAIQHAQDPVKLSAFVVILPLLFQILSYTYQTLSLAFRWGMHRSKLTAIYRSIQASKDSPSSLEKKVNWSKISANHHSTVADHNPMSITSPPSIESHSNLIRLTQRKGRLTLRGENGCGKSTALILIKDALASKAFLLPTHNQLSFTSETNKHSTGESLRKRLQEIADKVDVEVLLLDEWDANLDKGNQEILSGLIDLLAENKCVIEVRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR01</accession>
    <name>A0A0C1HR01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FL00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000073">
        <property type="protein sequence ID" value="KIC76578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76578">
        <property type="protein sequence ID" value="KIC76578"/>
        <property type="gene ID" value="DB41_FL00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="711" mass="81804" checksum="91B09E0CD0511B30" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRF1</accession>
    <name>A0A0C1HRF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383984.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76703">
        <property type="protein sequence ID" value="KIC76703"/>
        <property type="gene ID" value="DB41_EY00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="906" mass="103208" checksum="8834D74E61750325" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT56</accession>
    <name>A0A0C1HT56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="7">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 16" type="primary">gpsA</name>
        <name evidence="16" type="ORF">DB41_CO00220</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 13">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 11">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383118.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77253">
        <property type="protein sequence ID" value="KIC77253"/>
        <property type="gene ID" value="DB41_CO00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.56"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10 11" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 13" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="14">
        <location>
            <begin position="2"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="15">
        <location>
            <begin position="179"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="254"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KIC77253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="332" mass="35908" checksum="36762005276CD064" modified="2015-04-01" version="1">MKVGFLGAGSWGYSLASLLASKGYQLISWTARPELVKHLTEKREHPYLPGHTFNGSMKFTTDIKEALQGVDMLVEAVTSAGIRPVFEQVKTLGLPKCPIVITSKGIEQNTGLILPDVVVEVLGGNTRQQVAFLSGPSFAQDVIRKLPTSVVGSAYAPEVMRIVTDTFTTQTFRVYPNPDIHGVAYGGALKNIIAIACGMAEGLELGHSAKAALMTRGLHEIRKLAVARGCKAETLNGLSGMGDLCLTCGSLMSRNFRFGYLLAQGLSPQEAAVKIEMVVEGAYTCVSTLQLSHQLNVSMPITEIVYKIIYENLAPQEAVKALMQRTIKEEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK18</accession>
    <name>A0A0C1JK18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AU00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71630">
        <property type="protein sequence ID" value="KIC71630"/>
        <property type="gene ID" value="DB41_AU00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="81" mass="9619" checksum="A70A61DB0D3268AE" modified="2015-04-01" version="1" fragment="single">QIVKEIVENENLKQLFRNFEKTLDEIFVLRPSRKHLNAVQENVTFESSQKSCLAIKNKKVYHRVCSLREIKKKILVARVDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK37</accession>
    <name>A0A0C1JK37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AS00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71650">
        <property type="protein sequence ID" value="KIC71650"/>
        <property type="gene ID" value="DB41_AS00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6665" checksum="AED8B8A9978B74BC" modified="2015-04-01" version="1">MINNQFKNKRNYSCNYSGTFICLENFENLQKNFSLNKKFNVFRDISLCTGQKIIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL82</accession>
    <name>A0A0C1JL82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BL00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000232">
        <property type="protein sequence ID" value="KIC71346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039387001.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000232.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71346">
        <property type="protein sequence ID" value="KIC71346"/>
        <property type="gene ID" value="DB41_BL00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="500" mass="56022" checksum="0CA72D7D8332C6A5" modified="2015-04-01" version="1" fragment="single">DWIAENRKNITALDLSRIDLTYLPPEICQLSQLQTLDLRENQLTALPTEIGQLSELQYLYLNQNQLTALPAEIGRLSELQSLELNQNQLTSLPAEIGQLSKLQVLHLSQNQLTALPAEIGQLSELQALDLSQNQLTALPAEIGQLSELKTLDLRENELNNLPAEIGRLPQLQWLDLSQNQLVSLPEGIGRLSQLQELNSSQNQLTNLPEEIGQLPQLQWLYLNQNQLTALPSEIRQLFQLRGLYLNQNQLTSLPEEIGQLSQLQWLYLNQNQLTSLPAEIGQLPQLQELELNQNQLTSLPAEIGQLSQLQVLYLNQNQLASLPAEIGQLPQLQELELSQNQLTSLPAEIGQLSKLQELYLNQNQLTSLPVEIGQLSQLQGFELSQNQLTALPVEIGQLSQLQGLYLNQNQLTSLPAEIGQLSQLQELELNQNQLTSLPVDIGQLSQLRRLELNHNQLTALPTEIGQLSQLQGLYLNQNQLTSLPIEIGQLSPLLQLELAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMP2</accession>
    <name>A0A0C1JMP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SWIB/MDM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KJ00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72535">
        <property type="protein sequence ID" value="KIC72535"/>
        <property type="gene ID" value="DB41_KJ00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1928"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SSF47592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIB/MDM2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="10110" checksum="99A96F05FAF76618" modified="2015-04-01" version="1">MAKKNSAFMKPVQVSPELAEIVGQGSMPRTEITKKVWEYIKKHNLQDAQNKRNINPDAKLAKVLGNQSIDMFKMTSKISKHIKEPEAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNK6</accession>
    <name>A0A0C1JNK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KC00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72820">
        <property type="protein sequence ID" value="KIC72820"/>
        <property type="gene ID" value="DB41_KC00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4603" checksum="47DC8870C3BED865" modified="2015-04-01" version="1" fragment="single">MKKNIDANHATFCPQAFKCFEGALEAFFSHECPQLGGTRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPG9</accession>
    <name>A0A0C1JPG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KL00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000192">
        <property type="protein sequence ID" value="KIC72431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72431">
        <property type="protein sequence ID" value="KIC72431"/>
        <property type="gene ID" value="DB41_KL00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1969"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="623" mass="70753" checksum="0CE155656B71DF8B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPN8</accession>
    <name>A0A0C1JPN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JQ00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73155">
        <property type="protein sequence ID" value="KIC73155"/>
        <property type="gene ID" value="DB41_JQ00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="241" mass="28259" checksum="BB5FA6373B298944" modified="2015-04-01" version="1">MKYKKKFITLIELMVAMALTSLLLTLLLHFYHDMEWWNQDINKSQVKAFQIFYVQNRLSDILSHAVSPRTEEKDFFFYTSQDVNGLLKPNNPSLVFTYHFGPNRDPLFANHVLGRLYVDVHDNLRLATLPSPKFWPSLTSLKMKNEILMEGIESLAFNFYIPPQKDRSLVGNKAPQGSFNKDSYPLADIQPADSWEHSEWKSEYNQLPAMIKIILKAKERKEPITWVYPFPFSDFTIIYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQB6</accession>
    <name>A0A0C1JQB6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recX</name>
        <name evidence="2" type="ORF">DB41_KD00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Modulates RecA activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386293.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72711">
        <property type="protein sequence ID" value="KIC72711"/>
        <property type="gene ID" value="DB41_KD00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01114">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="23759" checksum="2B1EA22AC4E7999C" modified="2015-04-01" version="1">MKISCLPKEGSRLLMTVFIEEEPWRDIHTKIFGRQPLLPESDSLAAFQEKFKKLEYVKAKKYALDCLALRSYLSIQMKKLLKRNLVSEETIEEILQECTRLGYLNDHEWLEGFVKRQLARHTGPQRIICQLMNKGISRVEAHKYVEMYVQANTSQHSIQHLINTKYKTRNLADYREKQKVFAALIRKGFDIQAVKDTLKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSQ4</accession>
    <name>A0A0C1JSQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IT00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386058.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000151.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74140">
        <property type="protein sequence ID" value="KIC74140"/>
        <property type="gene ID" value="DB41_IT00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="120" mass="14030" checksum="D8DD7DC71EF5A2E6" modified="2015-04-01" version="1">MKKILIHVTIWSATLAISSLRLFAHGGGDHGSVKGEGHPSYEGFHGKHDHGWEHHHEDHQWHHEHGHSNVYVVDPWYNPGFVYSDTSVTYPYYYNGYPYYYYHPNYYWDNGINVNLNIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSX6</accession>
    <name>A0A0C1JSX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Stage IV sporulation protein FB</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">spoIVFB</name>
        <name evidence="5" type="ORF">DB41_IS00010</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000150">
        <property type="protein sequence ID" value="KIC74215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386056.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000150.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74215">
        <property type="protein sequence ID" value="KIC74215"/>
        <property type="gene ID" value="DB41_IS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="393" mass="44127" checksum="02289AE7D69E3DE8" modified="2015-04-01" version="1">MVTIPGKIPLRIYPFFWILTLIIGWLNSFSEITSIHAALIKTVLWVIVITFSIIVHEYGHALSALAFGQSSTIELAGLGGATYRTGPKLKLWQEFIIVLAGPLFGFALAWGTYLFLNRWGEHSSNLGIFALEICFYVNTFWTIINLLPVQPLDGGRLLSIALEGLLGLRGIKIASLLSILIATGVGLFFFAFQATLAGSMFLILAFESYRSWQSTSSMQEQDQNDAIKNLLKAAEEDLEEGRKQEASEKFRNIRNLTQSGVIYRQATYHEALLLSEKGEYKEAYEILYPLKNKFHLPIWQLLQDLAYHNQEWKEAIQLGDRIFSEAPSYQTALTNALSYAQLGAAKPAVSWLESAIRHGMPYTAPILSKVEFDSIRSCSAFQNLLKNCLNELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTH1</accession>
    <name>A0A0C1JTH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative metal transport system membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DB41_IP00050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386014.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74405">
        <property type="protein sequence ID" value="KIC74405"/>
        <property type="gene ID" value="DB41_IP00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1636"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Fe_dep_repr_C" evidence="9">
        <location>
            <begin position="377"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="450" mass="49796" checksum="99D18C2CA0BB2E27" modified="2015-04-01" version="1">MLFANSPYYYFTDAVLRAPTIGSMLMCLGASLVGVLVFLRKESLLGESLSHAAYPGVMIGVILAGILHLGEDQEMVVASLIMVAAGLTALGGLWAIRWLENSLKVPSDSALCFILAAFFGIGLTLASHVQFSFSTLYRQAQVYLYGQAATMTDIHIFVYGTLALLITLTLIFLYKEIQTILFNKDYAKSLGINVSGIDAIIFVLIVLAVVIGIRSVGVVLMSAMLISPAAAARQYTNRLSIMFVWAACFGLISGYLGNYLSIEISNYLASLYPSARLALPTGPMVVLVSSCICLLSLLLAPERGVLLRVLRIAKFRHRCMCENLLKAIWRIQGPHPVSFEQIAKHQSASKLYLRFALWRLVRNGWMVKAGKKAYQLTKEGNVWAAKIVRLHRLWEVYLVDYLGIGAEKVHLNAEEMEHVITPELEDKLIILLNDPKQDPHHQLIPAQINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTH7</accession>
    <name>A0A0C1JTH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tlcA_3</name>
        <name evidence="10" type="ORF">DB41_IP00100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386022.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74410">
        <property type="protein sequence ID" value="KIC74410"/>
        <property type="gene ID" value="DB41_IP00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1641"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187">
        <property type="entry name" value="PTHR31187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00769">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="517" mass="57718" checksum="150E8B7B5523334F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTZ4</accession>
    <name>A0A0C1JTZ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">obg</name>
        <name evidence="9" type="ORF">DB41_IJ00410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385954.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74570">
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        <property type="gene ID" value="DB41_IJ00410"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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        <property type="entry name" value="OBG_GTPase"/>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
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    <feature type="domain" description="OBG-type G" evidence="7">
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            <begin position="159"/>
            <end position="330"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="165"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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    <feature type="binding site" evidence="5">
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            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <begin position="212"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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        <location>
            <begin position="282"/>
            <end position="285"/>
        </location>
        <ligand>
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            <end position="313"/>
        </location>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="333" mass="36751" checksum="B2C4787FB4471F99" modified="2015-04-01" version="1">MFVDRVTIDLAAGKGGNGVIAWRREKYIPKGGPCGGNGGKGGSLILQADAQVFSLEWFRNRRILKAENGREGGPNCQQGRNGKDLILKVPCGTLVKNIHTGEILHDFTQDGEKWEICKGGRGGRGNDSFKSPTNRAPNTRTEGTEGQACSIELELKLIADVGLVGFPNAGKSTLFSSLASVKVKIAPYPFTTLRPNLGFITYKEHQRIFIADIPGIIKGAHCNRGLGFEFLRHIERTKLLLFVLDASGIDGRDPSSDFEVLRHEIQAYNPEMLERPYLIVLNKVDTEEASQHIKVFLKNKFAAKEKIFQISAMLGNGLPELREAIRLNIQQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JU53</accession>
    <name>A0A0C1JU53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">DB41_II00100</name>
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    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Parachlamydiaceae</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="DB41_II00100"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4881" checksum="BED3C877AF8A98E5" modified="2015-04-01" version="1">MNFLFLDSIKAFFKRDSTLKKNLIYIPNLLEAVFLFNDRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUB6</accession>
    <name>A0A0C1JUB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IV00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000153">
        <property type="protein sequence ID" value="KIC74016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386069.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000153.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74016">
        <property type="protein sequence ID" value="KIC74016"/>
        <property type="gene ID" value="DB41_IV00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8044" checksum="2033F28AA3B8E3F5" modified="2015-04-01" version="1">MIINGLGFTLGPIHEGIKELILSLNPNMRHVLLVLDLLGRNLMTREINLRNAGYYIDSGSLIDFYSSKLSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWX5</accession>
    <name>A0A0C1JWX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">celB</name>
        <name evidence="13" type="ORF">DB41_IB00740</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385759.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74941">
        <property type="protein sequence ID" value="KIC74941"/>
        <property type="gene ID" value="DB41_IB00740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1510"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05801">
        <property type="entry name" value="PGM_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005852">
        <property type="entry name" value="PGM_a-D-Glc-sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01132">
        <property type="entry name" value="pgm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="40"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="210"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="323"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="478"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC74941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="554" mass="61292" checksum="5A16C450B75A6848" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX66</accession>
    <name>A0A0C1JX66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243966.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75011">
        <property type="protein sequence ID" value="KIC75011"/>
        <property type="gene ID" value="DB41_HY00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="SSF54518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="204" mass="24179" checksum="562A4D97EAE52A1B" modified="2015-04-01" version="1">MLKKKLIILLFLFVAFNKLTIQAEEIPSKFYIRQHWISLTHTFDILSKDQPMGTVHRKHIKEGASHYLFYDPHNKLQAKAYMSFFDWGASLDIYDGDEQLLGKVEEKIVHFFPIFDLYRADGYHAASAKINLCGTKYTVIDPATHQVFAYLWRHFFSLKDDWTVEILDPTLFREQAIDYRLLILMLTFQIDHYHWQNMNPNSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXH9</accession>
    <name>A0A0C1JXH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HF00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75780">
        <property type="protein sequence ID" value="KIC75780"/>
        <property type="gene ID" value="DB41_HF00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="76" mass="9030" checksum="9B865953549A57C8" modified="2015-04-01" version="1">MACPVMHYLTAVDSAAWLCIRQIQIKRFWPKIKLFHFQLLIHCGYLKASKCAYYHLEMRAKLRKKAKLGFLFSLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXM0</accession>
    <name>A0A0C1JXM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">truA2</name>
        <name evidence="4" type="synonym">truA</name>
        <name evidence="9" type="ORF">DB41_HV00080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385457.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75136">
        <property type="protein sequence ID" value="KIC75136"/>
        <property type="gene ID" value="DB41_HV00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1351"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="144"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="248" mass="28141" checksum="243D26BAC8EA7DF8" modified="2015-04-01" version="1">MKNIKLQIAYDGTSYLGWQKTSLGPTIEASLEKVLERILQHPVTLQAASRTDAGVHAHRQVINFFTTKELLNYKSFKISLNQLLPPSLVVLEAQEAPQNFHPTLDCIQKEYHYFICKGAVQMPQNRLYSWHCPRLSKLAEMKAAAKLLVGKKDFSAFCNFKNHVHYASFVRQVNRIEIQEIFPDRLLFKVAGQSFLYKMVRNIVGTLAYVGMGKMLGSQIPAILANRDRRLAGITAPAHGLCLHQVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY24</accession>
    <name>A0A0C1JY24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HO00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385389.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000125.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75361">
        <property type="protein sequence ID" value="KIC75361"/>
        <property type="gene ID" value="DB41_HO00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="28471" checksum="BD3B3DB9E62EEA40" modified="2015-04-01" version="1">MKNPKINIIIQARMGSTRLPGKVLQPIMQRPLLGYLIERVRRIQTMHTLIIATTTHPQDDVIASFCEKEKVNIYRGHEHNVLDRYYKTCCEYPADIIVRLTSDCPLIDPAIVDQALNLLLKKSASLDYVSNTQLRTFPRGMDVEAFNFSTLESAYHKATSKFDLEHVTPFIYKHPDLFHLANFVHMRSAANYRLTVDTPEDFLLVSKIFETIYPTNKNFTLVDILDAFKTHPQWKKINAHVKQKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY26</accession>
    <name>A0A0C1JY26_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oligoendopeptidase F</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">yjbG</name>
        <name evidence="9" type="ORF">DB41_GU00040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has oligopeptidase activity and degrades a variety of small bioactive peptides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75955">
        <property type="protein sequence ID" value="KIC75955"/>
        <property type="gene ID" value="DB41_GU00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1021"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004438">
        <property type="entry name" value="Peptidase_M3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00181">
        <property type="entry name" value="pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="137"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="227"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="634" mass="73659" checksum="73553B7E1C73B318" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY44</accession>
    <name>A0A0C1JY44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="8 9">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">miaB</name>
        <name evidence="13" type="ORF">DB41_HN00130</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="8 9"/>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75381">
        <property type="protein sequence ID" value="KIC75381"/>
        <property type="gene ID" value="DB41_HN00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1291"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="11">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="142"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="10">
        <location>
            <begin position="376"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC75381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="460" mass="53067" checksum="1A0E55319B8406FC" modified="2015-04-01" version="1">MRKLQSFFVRTYGCQMNELDSEIMVGLLEGRGLVRTEDENQADLLLFNTCSIRDLAERKVMGKLGKLGHSLQNNPIIGVTGCMANAKKESLFQKLPHIDFVLGTNNIHELNHVLDEVLASDKQIVRTDEQFQFELDYLSAKRDDKVKAYISIIRGCDKFCTYCVVPYTRGPEVSRSPENILEECRQLVSKGYKELILLGQNVNSYGKDQPEWQCRFHDLLYQIDKIPGLQRVRFMTSHPVDITKELMEAIRDLKTLCEFVHFPMQAGSNRILKKMHRIYTIEQYLEKVHMLREIVPHVTLGTDIIVGFPTETAEDFQQTYDLMKQIEFSVAFLFSYSPRKGTPAMRWKDDISEEVKQERLQQLLKLHDEIAAKQRQRLLNTEVEVLVEKHSSKDKALLKGRTRCWKNVVFAGNEALIGSLQKVRIHGFNHQTLMGTLIASLEDNLTNFSKATEINKLRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY54</accession>
    <name>A0A0C1JY54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GS00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000104">
        <property type="protein sequence ID" value="KIC75980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384861.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000104.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75980">
        <property type="protein sequence ID" value="KIC75980"/>
        <property type="gene ID" value="DB41_GS00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="SSF90112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="28819" checksum="A5E1D75D6A7AFE1B" modified="2015-04-01" version="1">MSPFQKVLRFRFSNFIKLSLSSLFTIGGIWCLFIAFVYLGFPFAEIKVEKFFDLGFFSVSIFGLIIFLTMIPFQAVQERLSPGFFSRISSNPRAHFGLYVLITSAIICFLVIALQQIPIIEKYLSELFLALTVAIIFAIIFHHCWVIRHLYQPYVVYNHIKELKGEESAEETWLELFECVYKAIKQGRVSDARNIINLITHNFTQDVTKKENRMLYEDLTNLYTIARECRPIARLMEKKWPFLLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYC3</accession>
    <name>A0A0C1JYC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ylmE</name>
        <name evidence="5" type="ORF">DB41_HL00090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385325.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75476">
        <property type="protein sequence ID" value="KIC75476"/>
        <property type="gene ID" value="DB41_HL00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1268"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="25810" checksum="1ED39E91428483E1" modified="2015-04-01" version="1">MSIRDNYRALQQEIAETAHACNRKIEDIKLIAVSKKQPWEFIFPLYQEGCRNFGENRIQEALPKIKQAPPDCYWHFIGPLQKNKVRKAVGPFVLIHSVDSLDLANKIAEVSKQLNLITAILLQVNTSQEQSKQGMTCEECYQNFNDFLSLPHLDVQGLMTMAPLTDNEKIIAKSFERLRRLKEALLKDYKPSNQLPHLSMGMSQDYKLAIREGATLLRIGSKIWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYH2</accession>
    <name>A0A0C1JYH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KQ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386469.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72237">
        <property type="protein sequence ID" value="KIC72237"/>
        <property type="gene ID" value="DB41_KQ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="465" mass="53650" checksum="5B4432333CCC5E72" modified="2015-04-01" version="1">MSLTIEQMKKLLKEINSSLKEVLFDYCTAPHSQKIVLHFKEALPLLICFQEAFLRFHLTQYSGQDTSSFFSKKLTQHLRGWYLKSCELVNEDRILRMVFKKGELTQTLISELIPKKPHCYLVDSQRSILVSLHPTIHTSYIPPKTLPPLLSLGSPEDITSTSVEAMYRHKELEAEFLKKRNTLVAELKNKLNKTQKAEAKFSEELEKALLWEQAHHEASLLQANLYKITKGLRQVSVNDWLKDNREIILNLDPTLPPSEEVSKRFQKSKKLKKAIDPLSAQLKQAHQAVEKLSLMLEQVQQIETKQELESFCQIHEELSKKITKNKLAKKTLSLPYHEFVTQAGLKIWVGKNAHANDKLTFTYAHGSDYWLHARDGPGSHVILHLGKHLKPDEESLLDAIHAALFYSKAKERQEGEVCITQCKYVSRYKKNLPGKVHLSLQRITYAKIDLERLKKLKENKFTNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZS9</accession>
    <name>A0A0C1JZS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">rpiA</name>
        <name evidence="3" type="ORF">DB41_GU00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384879.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75961">
        <property type="protein sequence ID" value="KIC75961"/>
        <property type="gene ID" value="DB41_GU00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1030"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="34"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="235" mass="25765" checksum="D4787C43305E4E06" modified="2015-04-01" version="1">MSDNSFIGQQIAKKSAGYAAANLVENGMTVGLGTGSTTSFFIEKLAQRCEEGLKIQAVATSSQSQKLALEKGIPLIDINTLFSIDLTVDGADEIDPDKTMIKGGGGALLREKIVASMSKEAIIIVDQAKLVKKLGQVPLPVEIVPFAYPATIYRIEQLGYQGKLRTHDEKELYCTDNGNYIYDIYFKEKLEKAEQLHQRLSEIVGVVESGLFIRLAGRIIVGYNDGEVKIFTELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0I7</accession>
    <name>A0A0C1K0I7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76680">
        <property type="protein sequence ID" value="KIC76680"/>
        <property type="gene ID" value="DB41_FB00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5241" checksum="AAC637E746A39016" modified="2015-04-01" version="1">MGADVAFGKLGGKMKKHYGIKVSSSMVRLINQKHASKIAKLKKKRSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0L3</accession>
    <name>A0A0C1K0L3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383996.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76710">
        <property type="protein sequence ID" value="KIC76710"/>
        <property type="gene ID" value="DB41_EY00210"/>
    </dbReference>
    <dbReference type="GeneID" id="39482540"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="14643" checksum="6D5C06284131AA10" modified="2015-04-01" version="1">METAVQVLEKMENVLDQLVSNAEGLKDLSMEEFSEEAVTPLQQKQELLVEQLNGLEGSFEASEKEGQEEVLAKIGDRIAKKLRYFQHLNAVFVENITEGNFMEDYAKSDLEMLETGLPHRRHENTDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0M5</accession>
    <name>A0A0C1K0M5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EV00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000060">
        <property type="protein sequence ID" value="KIC76720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76720">
        <property type="protein sequence ID" value="KIC76720"/>
        <property type="gene ID" value="DB41_EV00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.577"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="23407" checksum="C29948F2C4955B5C" modified="2015-04-01" version="1">MLYLEQNQLTALPAEIGQLPQLQHLYLNQNQFTALPAEIGQLPQLQWLDLSQNQLTALPAEIGQLSQLRWLNLSQNQLTSLPAEIRQLSQLQHLYLYRNQLTSLPAEIGQLSQLTRLLLGENQLTSLPTEIGQLSQLTRLHLSVNQLTSLPVEIGQLSQLQLLYLSQNQLTSLPAEIDQLSQLRTLELAKNPLKDIAKKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0S6</accession>
    <name>A0A0C1K0S6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EO00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76765">
        <property type="protein sequence ID" value="KIC76765"/>
        <property type="gene ID" value="DB41_EO00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="33"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="136"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="507" mass="57648" checksum="EDBAFE70BC1E6441" modified="2015-04-01" version="1" fragment="single">MNLESFSINSFMFTTFKELAKEKPYLGLGPYAEISLKIFQELSQQDLSNARGVCKEWKQLIEQADEWKRLHLKKIKSNLPTNNQLANEANSLDPSRSPWSSSQIAKSLWDDPSTVISDAVKIKVNAVAAYLNKEGFELKGVAGDGDCFFSAFLGSYKGLSRKIPLLEEQSNKFSYLRQVLSDILKHTNSKRAKEIIKKGSWVSGLGEGDLLARALSIPIRLVTVNEDSLGCGINDMLISSKVGLTSKKDRSQEWKTIPQEKRPQDYIFIVDLGGHFIYAQKPLKQDKIFLSKSKISPNILFSNSLSTNELKNTLKTLDCQELLSDEEIKELEQTYTQALQMAVQEKDPLQESFCIEKLGDIYLRKQTSETLLQAAGLYNYALRLAPPQRQKILKDKLCQVQNLLVKQCKGKLFDSVVIEKQFERNRNGLKKFREEIEKKIQTLSENPPSQEVRELYHEIAHEIKIFFGQLVIQAIYQLDTAPCEYAMIGFGSLAREEMTPYSDLEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0W5</accession>
    <name>A0A0C1K0W5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GF00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76411">
        <property type="protein sequence ID" value="KIC76411"/>
        <property type="gene ID" value="DB41_GF00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4570" checksum="02ACB40727CB13C9" modified="2015-04-01" version="1">MLECALIAGMKEGSYVHAIIDGAPWIAKANKTKVLQSMRPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0X8</accession>
    <name>A0A0C1K0X8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protease HtpX-like protein</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">htpX_2</name>
        <name evidence="9" type="ORF">DB41_GD00090</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76431">
        <property type="protein sequence ID" value="KIC76431"/>
        <property type="gene ID" value="DB41_GD00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="96"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="222" mass="24897" checksum="AC30D5BB3EED207A" modified="2015-04-01" version="1">MAINFWEAQKKARSKTKLYLGLFLALTLLISTLVEYTMRNLAKDSYHPPIPLLGLAFLIITCGIALVEYSHYKLQGGAYVARSLGARLIDEHTNNLKEKQLLNIVQEIAIASSLPVPPVYILPTDAINAFTAGLTPENAAIAVTKGSLDKLTREELQGVIAHEFGHIYNGDIKISMRLAAMVMGFFYALYIGMRLLQFTSHSRERRKKKEIILSLLQLFLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K112</accession>
    <name>A0A0C1K112_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_IS66 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GB00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76471">
        <property type="protein sequence ID" value="KIC76471"/>
        <property type="gene ID" value="DB41_GB00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="42"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="179" mass="21280" checksum="5698A364643069F1" modified="2015-04-01" version="1">MWRRKNALIVEKIAEQHFLNMLKDLYNMAREFKPWQLILLLNIFKDVYDVAISPGTCVTSDEKFFKKLEAFENTLKAHLLATQVLHFDETGIRCEKKLAWVHVASSPRATLYTLHAKRGQQAMDEANILPHFKGIAIHDHWFPYFSYKQMLHGLCNAHHWRKLTFMHEEKQEEWAKQMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K123</accession>
    <name>A0A0C1K123_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase YncI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yncI</name>
        <name evidence="2" type="ORF">DB41_JR00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000174">
        <property type="protein sequence ID" value="KIC73127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73127">
        <property type="protein sequence ID" value="KIC73127"/>
        <property type="gene ID" value="DB41_JR00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="214" mass="24317" checksum="E355C529313F39DF" modified="2015-04-01" version="1">MDVSGAIVSMDALYAHIDTIDEILNKGADYIVGIKGNQGHLKAEAYNFFEQAKAVNYQGVEGITREETYEKNRGRIESRHVCVVNALQWLPQREKWHLQSMIEVRSERKVADKVEQAIRYYGSSRKAGAKEFAKWIRAHWAIENSLHHVMDVVFKEDASLSDVGFSAENMALIRRLATNIIRTMDSGRGITDARRNATYAPNYLRGLLGKVFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K150</accession>
    <name>A0A0C1K150_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FX00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76496">
        <property type="protein sequence ID" value="KIC76496"/>
        <property type="gene ID" value="DB41_FX00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4499" checksum="D6D71A5C1AA94251" modified="2015-04-01" version="1">MQDIKSKLATFNLTKLISSNGNKLVKQFLTSQLKKLQTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1E1</accession>
    <name>A0A0C1K1E1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76556">
        <property type="protein sequence ID" value="KIC76556"/>
        <property type="gene ID" value="DB41_FN00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4563" checksum="E2730F3E63BAA1E6" modified="2015-04-01" version="1">MIIHGLYFALGSIHESIKELTLILNSKRMAVLLVLNLLGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1N5</accession>
    <name>A0A0C1K1N5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DN00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76980">
        <property type="protein sequence ID" value="KIC76980"/>
        <property type="gene ID" value="DB41_DN00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.291"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="27501" checksum="0FA877279B17252F" modified="2015-04-01" version="1">MKYRWLTVLPAEIGKLSKLKQLDLGGNLLASLPAEIGQLTRLKQLDLSRNHLAFLPAKIGQLSQLPSLDLSDNQLAALPAEIGQLSQLTRLWLSDNQLTALPAEIGQLHFLKELYLVNNQLATLPPEFGQLDELRLLYLNNNRLTSLPLTIGQLYSLQELYLDNNRLANIPGTIGQLLDLDKLHLSNNRLTSVPNGLGRLPSLRELYLDNNKLTAIPESLRPLPGHFEVVVRGNPFLENVYKSKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Y3</accession>
    <name>A0A0C1K1Y3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FB00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76686">
        <property type="protein sequence ID" value="KIC76686"/>
        <property type="gene ID" value="DB41_FB00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5281" checksum="B8D7EE82E6F98D9C" modified="2015-04-01" version="1">MKREKFKWKPHKNQSADARNRGGIARSSEEAFVMKVERRGLYCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K230</accession>
    <name>A0A0C1K230_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EU00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383958.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000059.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76726">
        <property type="protein sequence ID" value="KIC76726"/>
        <property type="gene ID" value="DB41_EU00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002148054" evidence="2">
        <location>
            <begin position="26"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="112" mass="12184" checksum="C05B10A230F310F9" modified="2015-04-01" version="1">MNISFTRCCGFSLFILGGILLPLQADPSDQGNHTLSQYPQPSPKKSQAYRPPSDDQNYNNLTDPSANPSNIPPSNPPGFYGGFYGSPPPPTAKQSFPDKAAADELYKHIQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K262</accession>
    <name>A0A0C1K262_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Biotin carboxylase</fullName>
            <ecNumber evidence="5">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">accC</name>
        <name evidence="8" type="ORF">DB41_EO00140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383906.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76761">
        <property type="protein sequence ID" value="KIC76761"/>
        <property type="gene ID" value="DB41_EO00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.546"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="7">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="119"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="454" mass="49686" checksum="4BAB040D30AE9F55" modified="2015-04-01" version="1">MQKVLIANRGEIAVRIIRACHDLGLQTVAVYSQADAEALHVLHADEAICIGEAPAAKSYLKISNILSACEITGADAIHPGYGFLSENANFASICESCGLNFIGPAPASITLLGDKAKAKATAKKAGCPVIPGSEGIVSDLKEGLEVAKEIGYPIFIKAVSGGGGKGIRIAYSEEEFIRLFPAARAEADASFSNPDVYLEKMIVDPRHIEVQVIGDKYGNYIHLGERDCSIQRRRQKLIEEAPSPLLNSKLRQKIGQAAINVVKEANYHSVATVEFLLDADHHFYFMEVNTRIQVEHTVTEELTGVDLLGEQLSVAMGNKLRYAQEEINFKGHVIQFRINAENPAANFSPSPGRLEYYLPPGGPHVRVDSACYSGYQIPPNYDSMIAKLIVHGKDRLEAIAIGKRALREFHIGGVDSTIPFHLYMLHDKKFLHSDFHLSYIDGLIAEGCSFSLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2F9</accession>
    <name>A0A0C1K2F9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_ED00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000043">
        <property type="protein sequence ID" value="KIC76851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383754.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76851">
        <property type="protein sequence ID" value="KIC76851"/>
        <property type="gene ID" value="DB41_ED00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.451"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="854" mass="96930" checksum="BED8782FF3881A44" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2H0</accession>
    <name>A0A0C1K2H0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PI3K/PI4K catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CS00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383216.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77205">
        <property type="protein sequence ID" value="KIC77205"/>
        <property type="gene ID" value="DB41_CS00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="2">
        <location>
            <begin position="359"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="540" mass="61337" checksum="6B34BD8FEC82C930" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2H4</accession>
    <name>A0A0C1K2H4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383735.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76866">
        <property type="protein sequence ID" value="KIC76866"/>
        <property type="gene ID" value="DB41_EC00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.442"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="275" mass="31878" checksum="8B4FAD04F2106DD1" modified="2015-04-01" version="1">MNKLKMWNDHSSWSEAEQAWDERASKAAKEHPIKRLKQLPAMPGITKETSKNLKWKSLKWMITQDHQGAIRKGFFKHSLKYGWAFLKSILKPKPYKKEGNFFYYGLQDEEEFKMLLKKSNTLLVLGFSYCHKPFECPSGRFTDECIHDPAHAVCQQCFIGKAVHASKKETIIPLFIPTIHYIGGKIFEIVHHYPEKQVIFMITACEMTLEMFGDWGNMVGLKGIGIRLDGRICNTMKAFELSEKGIKPGLTVILEETQKRMISLIRYCQENKEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2M2</accession>
    <name>A0A0C1K2M2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DQ00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383598.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76946">
        <property type="protein sequence ID" value="KIC76946"/>
        <property type="gene ID" value="DB41_DQ00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7394" checksum="93AE2E8A8A8648DE" modified="2015-04-01" version="1">MSHPIGPHSSSSSEPLQIKSLKRPREVDEKGKEKQLDERVSTIFVNRVKEEIEAHPQFKAHLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2M6</accession>
    <name>A0A0C1K2M6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DP00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243783.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76951">
        <property type="protein sequence ID" value="KIC76951"/>
        <property type="gene ID" value="DB41_DP00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="14016" checksum="3D08DE12A5B611AE" modified="2015-04-01" version="1">MAKPLVTKKKADAISNGAFLVGLGILLYTHDWWPGILLVLWVAVLLRQYLTGRVYDTIVSTIILLGLFLVSFIKINWSVIIPILFVIGGTYLIFREYFYADEIIEEEILDERSDRANEHKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K348</accession>
    <name>A0A0C1K348_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase subunit PdxT</fullName>
            <ecNumber evidence="4">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pdx2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase glutaminase subunit</fullName>
            <ecNumber evidence="4">3.5.1.2</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">pdxT</name>
        <name evidence="7" type="ORF">DB41_CZ00120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="4"/>
    <dbReference type="EC" id="3.5.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383329.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77131">
        <property type="protein sequence ID" value="KIC77131"/>
        <property type="gene ID" value="DB41_CZ00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.187"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006543">
        <property type="term" value="P:glutamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PTHR31559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="136"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="193" mass="21298" checksum="951C0ADE0630150D" modified="2015-04-01" version="1">MTTIGVLALQGAFSKHIDMVHSLNVKAVAVRKPEDLSRCHGLIIPGGESTTIKRQIDFIQMSHPLKQFAQLRPLFGTCAGLILMSQEIIADPMQPLGIINVSVERNAFGRQYESFIANLKANLSSSQAEDVAAAFIRAPRIHQYGKEVEVLSTYQGEAVLVKQGMHLGATFHPELTQSTAIHKYFISLIKSHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3C6</accession>
    <name>A0A0C1K3C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein YeaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yeaC</name>
        <name evidence="3" type="ORF">DB41_CK00140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77286">
        <property type="protein sequence ID" value="KIC77286"/>
        <property type="gene ID" value="DB41_CK00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.28"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="50"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="261"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="330" mass="36842" checksum="AA08B43158D7DD68" modified="2015-04-01" version="1">MLLTDISTLAATIANANEKFMLARQEMGKAIVGQQEMVNYLLIALLANGHVLLEGLPGLAKTLAITTLAKVVDCEYKRIQFTPDLLPADLVGTSIYNFKEGSFSVSKGPAFTHILLADEINRAPAKVQSALLEVMQERQITLNGQTFHLQEPYLVLATENPIEQEGTYPLPEAQTDRFMLKVTMDYPSKEEEKEILKRMANLGSSIKVKPILTTEEILNARRMINEIYMDDKITNYILDLIFATRYPSQYGLDLQSLLLNGASPRASIALCIACKANAFLEGRAYVVPQDIKKIAPAVLRHRLRRSYEAEAEDVSTDEMIERILKTVPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5H4</accession>
    <name>A0A0C1K5H4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">General stress protein 16O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yocK</name>
        <name evidence="7" type="ORF">DB41_IJ00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385925.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74537">
        <property type="protein sequence ID" value="KIC74537"/>
        <property type="gene ID" value="DB41_IJ00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1587"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020458">
        <property type="entry name" value="Znf_DskA_TraR_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01102">
        <property type="entry name" value="ZF_DKSA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="6">
        <location>
            <begin position="45"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="121" mass="13694" checksum="73DCF1E2F7330381" modified="2015-04-01" version="1">MGLKKNDVAQFKKKLEEMRAQLTHILKGSTAEVKTPDEATGYSQHQADQGTDDFDRTISLEVTSREYHILRQIERALEKIDENTYGICDLTGEEIPLARLEAVPYATMTVKAQEQLEKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6G4</accession>
    <name>A0A0C1K6G4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase, IS4 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_ID00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000138">
        <property type="protein sequence ID" value="KIC74847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385867.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000138.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74847">
        <property type="protein sequence ID" value="KIC74847"/>
        <property type="gene ID" value="DB41_ID00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1543"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4277" evidence="3">
        <location>
            <begin position="5"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="128"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="537" mass="61306" checksum="7E0345479C0FFD12" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7G8</accession>
    <name>A0A0C1K7G8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75102">
        <property type="protein sequence ID" value="KIC75102"/>
        <property type="gene ID" value="DB41_HW00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5873" checksum="044C047CE4AB07F0" modified="2015-04-01" version="1">MSVGKLHLLILKFSLPLIFSVDFSLNLNQSLKAWSYRNFLPHLVWVINKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7J3</accession>
    <name>A0A0C1K7J3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">recN</name>
        <name evidence="5" type="ORF">DB41_HV00040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75132">
        <property type="protein sequence ID" value="KIC75132"/>
        <property type="gene ID" value="DB41_HV00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1346"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="4">
        <location>
            <begin position="16"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="348" mass="39509" checksum="FD6955F46B920261" modified="2015-04-01" version="1">MWIYFFIRRISPMLKQLRIKNIILIESAEIDFAEGFNVLSGETGSGKSAIMNAIRLTAGERAETGIIRKGADKGVVEAVFDIKGLVEVENLLELSGIDREEGAELYIRREIFATGKSRAFINHQLAQLSLLRALSTHLIHLVGQHANQDLLSLDRHRELLDLFGNIKEEVAAFSTSWEEENALQNELEQLINNEAQRLREMEVCHMVLEELEEAHLKVGEEEELFSEYTLLTHAEELGTKVQEVCQVLDGEKAALLPHLNRQQHVVGYLASLDPALKDLSEAFHNAVLELQEVASALTLYQSRLEYNPVRTSEINERLKLITRLKKKYGPTVEDMQSFAEESKKNCKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K871</accession>
    <name>A0A0C1K871_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hemL</name>
        <name evidence="9" type="ORF">DB41_HM00040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000123">
        <property type="protein sequence ID" value="KIC75392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385341.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000123.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75392">
        <property type="protein sequence ID" value="KIC75392"/>
        <property type="gene ID" value="DB41_HM00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1276"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="435" mass="48211" checksum="DA6118CBD6714347" modified="2015-04-01" version="1">MLARPKSLEIYRRLCEVIPGGVNSPVRSCQNMHQPPLVAERAWQDLLYDADGHAYIDYCGSWGALIHGHAHPQIIEAAQKRMALGSTFGITTSIEEELARYVITLMESIDKIRFVSSGTEATMSAIRLARGYTQRELIIKFAGNYHGHADFFLVQAGSGVAGFLPQASSQGIPPEVVRYTICLPYNDIEGCRQVMRDPKNRERIAAVILEPVAGNMGVVPATQEFIHMLRQETSATGALLIFDEVMTGFRVGLKGAQGLYGVRPDLTTFGKIIGGGFPAAAFGGRRDIMDCLAPLGSVYQAGTLSGNPVAMEAGLQALKLLNQEGFYQELLRKTNLITQPIQEYLLSTDKQACIQQVGSMFTLFFGSKKVTHFGDTKQLDNEMFACFFRYLFANGIYIPPLHIEAWFVSQAHREENLIKTRDLILEFLKKEMPCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB92</accession>
    <name>A0A0C1KB92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_37 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GF00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243878.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000091.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76417">
        <property type="protein sequence ID" value="KIC76417"/>
        <property type="gene ID" value="DB41_GF00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.885"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_37" evidence="1">
        <location>
            <begin position="22"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15128" checksum="BE173CECEA210DBA" modified="2015-04-01" version="1">MVIRKKQQKIEGIEFEISSDNIFADIGVANAEEELTKAELAWEIDNIIKKRKLTQQKAAIIMQINQPKVSALLHRKLAGFSIERLLHFLNLLGQDIDIVVKPKPQNRKNARVNVFGYKEYSGILPSSPMAAKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBT5</accession>
    <name>A0A0C1KBT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FK00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76587">
        <property type="protein sequence ID" value="KIC76587"/>
        <property type="gene ID" value="DB41_FK00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002148224" evidence="1">
        <location>
            <begin position="20"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="526" mass="59901" checksum="B0A483FE024AC5AB" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC60</accession>
    <name>A0A0C1KC60_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Competence domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_FA00010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000063">
        <property type="protein sequence ID" value="KIC76687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384021.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000063.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76687">
        <property type="protein sequence ID" value="KIC76687"/>
        <property type="gene ID" value="DB41_FA00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Competence" evidence="7">
        <location>
            <begin position="161"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="445" mass="50151" checksum="A7A229719DC2E7F8" modified="2015-04-01" version="1">MYSSLAFQPPHLPGQGVTGTALIHISSLSRKNTFMGKSWSYQGRLLSFTGHESLNIYPNISVIISLLDHASLNRPLANKTYLLQGRLKQSKNGKFIFKPDKYHPWHPITNSWGLAEWRFNAKKAVNKYISQKISKNPNSPSSSFLSGITTGEFENRLMAFEFSRFGLQHIMAISGFHFAIVAGMLGFILSWVVGQKTSVSLLMLFMTLYFAFLGPSPSIIRAWVSCMLGFGATLLEKPPSGLNSLGIGLLIVLIFDPELALHIGFQFSFAVTAAILISYFSFDYLLQKIFAKKTFNQLMAMNLANQHGFIILTLFRQALALSIAVTLAALPLTLYYFQKFPLWSIIYNFFFPWMVSLALMFLLAGLMVGILSSSLAQIIHHFNESFTNFVLDYAYGMPKSLDYNINLLVNQEIAILWLGIYFLAGIYGRNYLSKQQKITSQEFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCN2</accession>
    <name>A0A0C1KCN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EG00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76837">
        <property type="protein sequence ID" value="KIC76837"/>
        <property type="gene ID" value="DB41_EG00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="141" mass="16559" checksum="B794EF7BF3F17335" modified="2015-04-01" version="1">MAMHNLALIEEKFKEFYKNITLASSELLIPVNLSLLHHMKLLYFHSPWNKDQSLTRYFQLIESSGKLTLINEDFVVWIVPENAHQIPLTYTVIALNYPEGPKLELIFSAAGVYNTSRTVLRVLEKFLYEIQENEEYLKKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCQ8</accession>
    <name>A0A0C1KCQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76857">
        <property type="protein sequence ID" value="KIC76857"/>
        <property type="gene ID" value="DB41_EC00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7924" checksum="6BE27E2F2381911F" modified="2015-04-01" version="1">MGELIKKIGVDFAFQKPAYRQLRVCNEHEETSSFHFAGRDVFCFAQKAIFKIFSKNALKNRRSLRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCY0</accession>
    <name>A0A0C1KCY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative zinc metalloprotease</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DB41_DT00110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383657.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76917">
        <property type="protein sequence ID" value="KIC76917"/>
        <property type="gene ID" value="DB41_DT00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.400"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="576"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="10">
        <location>
            <begin position="11"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="654" mass="74268" checksum="0EF18DDCFD540A56" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDU9</accession>
    <name>A0A0C1KDU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CW00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77152">
        <property type="protein sequence ID" value="KIC77152"/>
        <property type="gene ID" value="DB41_CW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="9796" checksum="CDD571C2E523BDD5" modified="2015-04-01" version="1" fragment="single">MLFNFFILSSKNNNAEKFITTQGNKMHPISSTSIESLPYELLLPILEACVAPSLFSVCKRWHHLLASEVMPPLYKQIGKVHVPQGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDV4</accession>
    <name>A0A0C1KDV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CW00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77157">
        <property type="protein sequence ID" value="KIC77157"/>
        <property type="gene ID" value="DB41_CW00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5883" checksum="D40A5953361F0A39" modified="2015-04-01" version="1">MNKQNLNTVLKLNTLLLFMVQKQLNKTKTKLNIQAAEYKRNKKNKIFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDY0</accession>
    <name>A0A0C1KDY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2</name>
        <name evidence="3" type="ORF">DB41_CU00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000011">
        <property type="protein sequence ID" value="KIC77182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243750.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77182">
        <property type="protein sequence ID" value="KIC77182"/>
        <property type="gene ID" value="DB41_CU00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.127"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="423" mass="47114" checksum="AD201D0004862B4C" modified="2015-04-01" version="1">MDLTFLPSEIGQLSQLQTLELSCNQLTFLPPEIGQLSQLQELHLNDNQLTFLPLEIKQLLKLQTLNLSGNQLAALPVEIGQLSQLQTLNLRMNQLTALPAEIGQLSQLQTLNLRMNQLTALPAEIGQLSKLQTLDLNSNQLTFLPPEIGQISQLQKLDLNSNQLTSLPAEIRYLPQLQELYLSHNQLTTLPVEIEQLSQLQTLDLSHNQLTSFPAEIVQLSQLQDLNLRNNQLTSLPAEIGQLSQLQTLGLSHNQLTSLPAEIGQLSQLQYLDLYHNQLTTLLAAIGQLSQLQELYLSHNQLTSFPAEIVQLSQLQKLYLEGNQLTTLPAQIGQLSQLRSLDLSSNQLTTLPAEIGQLSQLKYLNLENNQLTALPAEIGRISKLQTLNLQISQPTFFPPPEIGRLSNQLNLKLSGNPLQNIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H0J1</accession>
    <name>A0A0C1H0J1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BS00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000239">
        <property type="protein sequence ID" value="KIC71274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71274">
        <property type="protein sequence ID" value="KIC71274"/>
        <property type="gene ID" value="DB41_BS00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="120" mass="14063" checksum="FAEC6E8E6B45685A" modified="2015-04-01" version="1">MVNNMTPFSLIPSIRIPEEVQLKILSLLDEKELPIAGLVNKHWQRMAQDPSLWRPICQRRWKNLSHSSSPGKNWQKICKKRVQMSQTMRLTKGEYSKNKCKQTIYKLPNFSGKILALKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H0Q6</accession>
    <name>A0A0C1H0Q6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BM00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000233">
        <property type="protein sequence ID" value="KIC71339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71339">
        <property type="protein sequence ID" value="KIC71339"/>
        <property type="gene ID" value="DB41_BM00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2292"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="165" mass="18714" checksum="96F7D990927E2FFD" modified="2015-04-01" version="1">MSQLQRLYLNQNQLTSLPTEIGQLSQLTRLYLNQNQLANLPAEIGQLSQLQRLELNQNQLTALPVEIGQLSRLQRLYLNQNQLISLPGEIGQLSQLLDLHLNQNHITSLPGEIGQLSQLLNLHLRQNQLTALPTEIGQMSRLTQLELAENPLEDIPGKIRQHFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1P2</accession>
    <name>A0A0C1H1P2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UvrABC system protein B</fullName>
            <shortName evidence="5">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">uvrB</name>
        <name evidence="9" type="ORF">DB41_AV00340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71594">
        <property type="protein sequence ID" value="KIC71594"/>
        <property type="gene ID" value="DB41_AV00340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2272"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2 5" id="KW-0228">DNA excision</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="23"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="428"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="5">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="614" mass="70966" checksum="2D3964542373AF57" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H318</accession>
    <name>A0A0C1H318_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AC00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386608.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000203.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71989">
        <property type="protein sequence ID" value="KIC71989"/>
        <property type="gene ID" value="DB41_AC00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="197" mass="23078" checksum="054A2142757DCEF2" modified="2015-04-01" version="1">MSLNDEFNLDHLDIINCYFKKTSLKSSVVYKWLENARRQAITHSTDSKFPIVRRDFTTYLDKRIATFQACILKEPKKNSALVPDIWRAKFAESSSNQTILLTASMHVHDLLFACHEIIEHLNLHSNHWMKKELTPFIDESLPTYLDLLPNLSDQLKCDIHASFEELKNLMIQEDFRRAEAQLNLIQNRIMPTQKAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3I8</accession>
    <name>A0A0C1H3I8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KV00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72094">
        <property type="protein sequence ID" value="KIC72094"/>
        <property type="gene ID" value="DB41_KV00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5250" checksum="10AE92A18F8248DE" modified="2015-04-01" version="1">MFLKQISQSLPTSSHALLILGRASYHTSKTLKVPSNIYLLFLPPYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5F8</accession>
    <name>A0A0C1H5F8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KD00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72704">
        <property type="protein sequence ID" value="KIC72704"/>
        <property type="gene ID" value="DB41_KD00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5418" checksum="164BB0AB6F15B956" modified="2015-04-01" version="1">MISTLLRIGICLPISLVNLLELSLNQGKNDCLEFKMLFYKVYNVIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAX0</accession>
    <name>A0A0C1HAX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74544">
        <property type="protein sequence ID" value="KIC74544"/>
        <property type="gene ID" value="DB41_IJ00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4959" checksum="698B5B96CF28034F" modified="2015-04-01" version="1">MLGFLEKQMNARVNWLVKSKLQPSSSMQAIISFIRKLPLRANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAY1</accession>
    <name>A0A0C1HAY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rnr1</name>
        <name evidence="14" type="ORF">DB41_IJ00250</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 12"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74554">
        <property type="protein sequence ID" value="KIC74554"/>
        <property type="gene ID" value="DB41_IJ00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1605"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="13">
        <location>
            <begin position="9"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC74554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="780" mass="88046" checksum="28A43132F483E50C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAZ1</accession>
    <name>A0A0C1HAZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74564">
        <property type="protein sequence ID" value="KIC74564"/>
        <property type="gene ID" value="DB41_IJ00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4884" checksum="86AE716C643A2AF4" modified="2015-04-01" version="1">MVFILITCLNFPKLCQAIVFFLYIDRAKNNIKIYIYLKEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB58</accession>
    <name>A0A0C1HB58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AA00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72028">
        <property type="protein sequence ID" value="KIC72028"/>
        <property type="gene ID" value="DB41_AA00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7779" checksum="28B7A171AC9C85EC" modified="2015-04-01" version="1">MEIIITCIRLFRYLTKRGQGSLLNKKRLNKGKFFPCLRKTLRKGFSMNFLAFLFSLCLIFPIYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBT0</accession>
    <name>A0A0C1HBT0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_KQ00230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386497.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72258">
        <property type="protein sequence ID" value="KIC72258"/>
        <property type="gene ID" value="DB41_KQ00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2030"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="21"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="190"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="313"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="354"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="395"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="481" mass="54030" checksum="D7F6AC382893FC8F" modified="2015-04-01" version="1">MQINNLSYFPPTLLNPSYSFSSPILRLPEELLTLIFSYLSTKDLVHAGMVCRQWDRIKEDPILWTSLYRYDFPFFTSPNSSYTRAMYINSFVTQNNLKTGKIQKEIELPPYVGGKTFFDFSDKAGFLLVEVADKTRLWNLAHGRFQDSPTQLKGDICSLFSPDGSLLATASSDGTVYLWNIITSALIHNLKGHTGVVIDAVFSGDGKMLAILSDDRLVHLWKISTGECLHIFSHTEEIIHAIFSPDGRTLTVEDDNNKLHLWDIAKGQPIHVLNYDGEIYENVFSPRGELLATIFEEKTVRVCKVPTGELLYTLNHEGDLWDCCFSPDGNLLATASQDHTVRLWEAVSGRLLHTFKHAGEVNKVAFTPDGSKLAAACQENYAILWDICSGQAIHYLKHEKEVQSVFFSPDGSVLVTTNFQGQVNLWTVAEGVQFANLRSPNTIYNEIRVAFSKDGSMIALATDFNIRILSFNPLFLNSSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCH7</accession>
    <name>A0A0C1HCH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KK00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72488">
        <property type="protein sequence ID" value="KIC72488"/>
        <property type="gene ID" value="DB41_KK00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="392" mass="45926" checksum="2E937CC3BC408029" modified="2015-04-01" version="1">MPLRNFFIINSNMPDKNHYLFLTAFFIATLIALISIVSFNYLIDPFDYFKPPIIVGFNDKKLESTQERFDKAAKIIVKKPTAIMLGSSRVRAGFPITYYTQLAGGQAYKAAFSGARFDEIFGYFEHALYNQPDLKAVFLSLDFFAFASQLEPVAEYREDRLRRASLSFSDWAQCLLSQQTIKFSWSTFKHNINPKKLEEVAGYYVKIDENDFILLNPIIVENPVQFLKEEKRLIFNNYEIDDKKVTMFRKLVQRCQENNIDLKVVFSPAHVYYWEALYQCNCWKALENLKRQLSAIYPIYDFSGFCAFNQEDLSVGNSNRHFFEVSHFTPLYGQIILDRVYGKENGCQEQEAGFLLNPQTVELHLTKIRKQRDDWIEKNFDLVIWLQNQLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCH9</accession>
    <name>A0A0C1HCH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycos_transf_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KK00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72493">
        <property type="protein sequence ID" value="KIC72493"/>
        <property type="gene ID" value="DB41_KK00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1955"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="189"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="431" mass="49821" checksum="E3DD31D960F48932" modified="2015-04-01" version="1">MVRILLNCLDTLGKSMAGPAIRYWEFAHALAKSHQVTLRVPNQTDQISTTFTISTGPIKFKKIDVIITQTIDPSLAFHAKRYKIPLIYDAYDPEPLEHLEIFKPSALKVRKHLNRAIIHTINFNLRMADAVICANHRQRDLWMGSLLSLKKISPTIYDQDETLHKRVGIAPFGIPSRPAIQSKSGFREKFNIKASDKLLLWGGGIWNWFDPLTLIRAVKELSKQRSDIKLVFMGIRHPNASIPIMSMANKAIKLAEDLKIKDQFVFFNEQWIPYEERENFLLDADIGVSTHFEHLETQYSFRTRLLDYIWAGLPLITTEGDVFAELVLKNKIGKVVPAQDVRALVLAISQLIDDSAETLRIKSNLKELREQLVWEKAVAPLEEIIEHLINNPLKNYFAYDLAQILYYQFQKCHPWTLVERWWIRRNNGIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD72</accession>
    <name>A0A0C1HD72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">parE</name>
        <name evidence="6" type="ORF">DB41_KD00130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244040.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72713">
        <property type="protein sequence ID" value="KIC72713"/>
        <property type="gene ID" value="DB41_KD00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1871"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Toprim" evidence="5">
        <location>
            <begin position="398"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="622" mass="70658" checksum="98EA876446AD69D4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDI2</accession>
    <name>A0A0C1HDI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative membrane-bound serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HL00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385331.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75479">
        <property type="protein sequence ID" value="KIC75479"/>
        <property type="gene ID" value="DB41_HL00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="57"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="153" mass="16699" checksum="752BC360DFEC12F4" modified="2015-04-01" version="1">MSPLIFLVLGFILIFIEFYLPGALMGIVGGICILASFSMFARQTESFLLVILYVMGSGVALAFLIKFALWRIRTEKPQHSIYSADTQDGYRAVDYDASTIGKSAIVLTDLKPGGFIIVEGKQQPAISQEGYLSKGTKVLVIGGNESNLIVRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEB3</accession>
    <name>A0A0C1HEB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HG00240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243932.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75769">
        <property type="protein sequence ID" value="KIC75769"/>
        <property type="gene ID" value="DB41_HG00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="316" mass="35693" checksum="EDC4E597B3C8BFA4" modified="2015-04-01" version="1" fragment="single">MHPISSTSIESLPNELLLPILEACAVPSLFSVCKRWHHLLASEAMTSLYKNIAQLHFPKKNATTQRTLLLAKVYQLNPGLTSTEKVYQVFKQVFTLAKSISPLEFKEKTEEKKGLTLANYSSYLLNTNRLLLWKKLPGGEEYLNREEIKHLPLGKKGELLRDWIKKKCKIKVLNLSQAGLTYLPPEICQLSQLRELYLDQNQLTSLPAEVGQLSQLQGLYLNQNQLTSLPAEMGQLSQLQVLYLNQNQLTSLPAEIGQLSNLLQLHLGQNQLTALPTEIGQLSDLQWLGLNQNQFTALSAEIGQLSELQRLELNQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEE4</accession>
    <name>A0A0C1HEE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">F-box/WD repeat-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fbxW7</name>
        <name evidence="5" type="ORF">DB41_HE00200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385102.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75804">
        <property type="protein sequence ID" value="KIC75804"/>
        <property type="gene ID" value="DB41_HE00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="12"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="125"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="166"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="206"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="246"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="367"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="452" mass="51992" checksum="202F9B159CD53426" modified="2015-04-01" version="1">MHPTFFPSSPSSSSFFSLPEELHLHLFSYFNAKELCQLQRVCKYFQRMIKDPYLWSKRLKKDYSYHFFSYQKQVNPFYKNQDLLPMQLAEIPPTSFYADNWKTKYRNLVKIKKNMENGEYTFSTLQSHGSYVKCIKIANGSLYSGAIRDGTIGVWNIENGEQQDSMKGHQSSVNCLKVEYGRIFSGSSDKTIRLWNIQTKKSQGTFHGHESFIGCLKVDQGRLYSGSSDDTIRLWDIETQQQLSVLKGHTASIECLKLINGLLFSGSEDKTIRCWDIKRGKEICCLRHDNWVTSMKVVHGKLFCGSACEDTRVKVWDIKKGLLTYLPTENDWGITDVKKLGNNIITSSRRGPIKIWDANTEQPLLTLNGHRRGVNNLQIAYGNIISASEDKTIRIWDPLKKQSMLTLKEKNEETTCLKVRHGRIFTGYATGAICEWDFRDSVLQDESPSFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFD9</accession>
    <name>A0A0C1HFD9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">ispH</name>
        <name evidence="6" type="ORF">DB41_GN00140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384789.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76104">
        <property type="protein sequence ID" value="KIC76104"/>
        <property type="gene ID" value="DB41_GN00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.975"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="312" mass="34017" checksum="262C6C2DC855A972" modified="2015-04-01" version="1">MKLLLSKPRGFCAGVERAIETVEKALSLWGRPIYVKHEIVHNKHVVESLKAKGAIFIEEVDEVPMGARLIYSAHGVSPAVRAAAQKRNLIEIDATCGLVTRVHSAVKRFANLGYQIILIGHRHHVEIIGTAGEAPDVTTIVESVEDVENLTFQSSDKLFYITQTTLSLDDVGEITQALIAKYSHIVTLPSSSICYATTNRQLALREITDATDLVLVVGDPQSSNSNRLRELAANKGIASYLINDDSEIDPQWIKGVKIIGLTAGASTPEGIVQDCIKKLITLGVKEVEDVVFTTEDVVFQLPKPIVNARFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFF5</accession>
    <name>A0A0C1HFF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000098">
        <property type="protein sequence ID" value="KIC76124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384771.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000098.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76124">
        <property type="protein sequence ID" value="KIC76124"/>
        <property type="gene ID" value="DB41_GM00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="9977" checksum="F4AC66F0D0B36AC7" modified="2015-04-01" version="1">MTAHSHRVKVTIDVSEDERTYIKMLAAKKRMTISDFIMSFVRPNIPHGHPNAETQKAMRDVDERKNLTHCKTIEEFWAAVRIDPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFX2</accession>
    <name>A0A0C1HFX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_GL00200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384747.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76279">
        <property type="protein sequence ID" value="KIC76279"/>
        <property type="gene ID" value="DB41_GL00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.954"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="382" mass="41552" checksum="8E730A3047F79A04" modified="2015-04-01" version="1">MNTKFLFVSTGFALFAMFFGSGNLVFPLLVGIESQGHYLISSLGIIFTGVLVPFLGVFAMLLYKGETNEFLGTMGSFAKFWFPLIALSLMGPFGVLARCITVAHGSFTLLFPNCSLIVFSLAFCGILFLLTTNKSQIIPFLGSALTPFLLLFLLAIIVAGMWYGQLLEPYNPNYWSAFHEGALQGYQTMDLLAAFFFSTFVIKHLSNHFSATSDNSQLVKVFIKSALLGGGLLAIVYCGLVYLGAAFASDLKGIAPQMLLGIISQKTLGALSAPVVCSAVILACFTTAVVLTSLFADFFKQQVCRESIHSSLSLLFTLLIAFGVSTREFSGIATFLAPILETLYPALIVLTLINIAHKLGGIKLRRWPVMLTFAVKLYFLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFX5</accession>
    <name>A0A0C1HFX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76284">
        <property type="protein sequence ID" value="KIC76284"/>
        <property type="gene ID" value="DB41_GL00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5437" checksum="BC04B9D51FA86972" modified="2015-04-01" version="1">MAYCKLEFLKIKTLLNHFALKYKLILKANQMAYQELQNLQRSSMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFX9</accession>
    <name>A0A0C1HFX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_JG00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042242691.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73563">
        <property type="protein sequence ID" value="KIC73563"/>
        <property type="gene ID" value="DB41_JG00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC73563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="228" mass="25729" checksum="9A78ED076E38C8FF" modified="2015-04-01" version="1">MAQEIAVRCQDVVKSYGTAKMQQMVLKYLTVDFFSGQLAFLMGPSGCGKTTFLSIISTILKEDKGRIQIFGKNTRDLNEEEKTKFRCENIGFLFQNFYLMPSLTCIENIELPLLLQNKSKQEARNRAYEALADIGIAPLANRWPQELSGGQQQRIALARALIHQPQLIICDEPTSSLDHANGLIVMNLLKTHALKSKNAVIVATHDKRILEYADRIIELNDGIIEKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG29</accession>
    <name>A0A0C1HG29_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_JE00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000162">
        <property type="protein sequence ID" value="KIC73603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244018.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000162.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73603">
        <property type="protein sequence ID" value="KIC73603"/>
        <property type="gene ID" value="DB41_JE00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1729"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="446" mass="50830" checksum="4F862FFE7B0E781D" modified="2015-04-01" version="1">MHTHNSITLEHLPNEMLTSILKYCTTPSLSSVCRKWRHLLASEVMPSLYKQIVKVHFPQGNVNKHAFILDKIYELDHELLPLQKVKAIFKQAFTLAKSLFSLEFKDTSQEYIYLTSANYTTYLLNINRLLIWKKLLSGEKYLEQEEIKHLSLAGKGKLFKDWIERYGRAITSLQLEGIGLTFLPPEMWQLSQLEELFLNNNNLTILPDELGQLRGLKMLRLDHNQLTTLPARICQLSELVVLDLGHNQLTALPVQIEQLSQLQVFLLSHNQLTAIPAQIEQLSQLQVFLLSHNQLTAIPAEIGQLSNLQKLWLSNNQLTAIPAEIGDLSQLQTLDLNNNQIIAVPTAIGRLFELEGLWLSNNQLTAIPAEIGQLSNLQKLWLSNNQLTTIPTEIGRLSHLKILDLAHNQIATFPIEEIEELPHLEILLRTQPIYPFSAEIMRSGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG76</accession>
    <name>A0A0C1HG76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UPF0391 membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_JC00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000160">
        <property type="protein sequence ID" value="KIC73668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73668">
        <property type="protein sequence ID" value="KIC73668"/>
        <property type="gene ID" value="DB41_JC00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01361">
        <property type="entry name" value="UPF0391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009760">
        <property type="entry name" value="DUF1328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07043">
        <property type="entry name" value="DUF1328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036466">
        <property type="entry name" value="UCP036466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC73668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6282" checksum="C96C6819371EB0AA" modified="2015-04-01" version="1">MLYWSLTFLIIAIVAGLMGFRGIEGIAATIAKVLFIVFLILFIITMVSGYGMMGAPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG99</accession>
    <name>A0A0C1HG99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">pyrG</name>
        <name evidence="12" type="ORF">DB41_GG00070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384607.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76399">
        <property type="protein sequence ID" value="KIC76399"/>
        <property type="gene ID" value="DB41_GG00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.891"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="4"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="305"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="386"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="513"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="189"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="539" mass="60693" checksum="66CF09A46E5058F5" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGI6</accession>
    <name>A0A0C1HGI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_Tnp_IS630 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GB00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76469">
        <property type="protein sequence ID" value="KIC76469"/>
        <property type="gene ID" value="DB41_GB00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002622">
        <property type="entry name" value="Transposase_14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01710">
        <property type="entry name" value="HTH_Tnp_IS630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_IS630" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="13865" checksum="28849824907575B9" modified="2015-04-01" version="1">MVYSLNLRKKALNFIENGGSIATASVVFGVAARTLTNWIKRKKQGNLAPKKRRQSPTKIDSEKLKLCIKQTPDAYLREIAEEFGVTTAAVFYACKRLKITLKKIHPSIRKEMRISERNVDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGW3</accession>
    <name>A0A0C1HGW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384291.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000075.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76559">
        <property type="protein sequence ID" value="KIC76559"/>
        <property type="gene ID" value="DB41_FN00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="165" mass="18540" checksum="669C41D8D16B4292" modified="2015-04-01" version="1">MTASGLNGGTLVGLPDYKVNDLIREQIPDNTFTSVTVKTVMHRFFGEETEITSRKITLERSNLSVGWEVARAFFLQLFNEAGARSRYRDNPRAINGNLVASFLALDPAFDDREQARAEEELKIVYARCMTITLYISDDCNYLDAETLKEHKALVGARNIAKCILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHS6</accession>
    <name>A0A0C1HHS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76864">
        <property type="protein sequence ID" value="KIC76864"/>
        <property type="gene ID" value="DB41_EC00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7173" checksum="CF9EC98B4F405AFC" modified="2015-04-01" version="1">MRLLKPLIEPQIKGMHSSLVGNLFACLLLELEEPTNSPKGEGLATLAFIKREIKTLAGTFSCRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHW6</accession>
    <name>A0A0C1HHW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DT00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383660.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76919">
        <property type="protein sequence ID" value="KIC76919"/>
        <property type="gene ID" value="DB41_DT00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="100" mass="11212" checksum="46272F287BCBA6A6" modified="2015-04-01" version="1">MPSTEASVAGFINLPTKPVSNYQIKQQKVLAKLAQDLPAMMEVWNVDSFQILTSEQMLAEGYEYEVAYSGDRILLFHKQIENQEAGRAAIDPLPPQEKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHX9</accession>
    <name>A0A0C1HHX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein lap1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">let-413</name>
        <name evidence="4" type="ORF">DB41_DS00150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243790.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76934">
        <property type="protein sequence ID" value="KIC76934"/>
        <property type="gene ID" value="DB41_DS00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.388"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="472" mass="54319" checksum="5BE92DB484740E9F" modified="2015-04-01" version="1">MNPSSSVTIDHLPNEILTPLLEHISSPALFSVCTRWRHLLATEVMPSLYKQIGKMHFPQGNVSEQAFILDKIYKLEDRPSEIEKVNAIFKQTFNLASSLAPMKLEFKWKSEETRFFTLANYSSYLININRLLMWKKLPGGEEYLEQEKIKYLSLTKKGELFEQWIERYGRDIKSLDLRGLGLTFLPMEIGQLSQLQELYLNYNHFITLPAEIGQLSQLQELYLGNNQLTSLPAEIGQLSQLRRLYLNDNHFTTLPARIEQLLQLRVLSLIRNQLTTLPTGIKQLIQLQELNLNYNQLTTLPTEIKLLSQLQSLNLSHNNFNSLPTQVGQLSNLQELFLSGNQLTSLLAEIGHLSQLQKLDLSDNQLTSLPAEIGQLTKLKMLNLDHNELTSLPAEIGQLAWLEMLNLDYNQLAMLPAEIGYLSHLQKLDLSDNRLTILPEEIEQLTEQLLDLRLDGNPLESIPRELKKRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIH1</accession>
    <name>A0A0C1HIH1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">folP</name>
        <name evidence="3" type="ORF">DB41_DH00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383422.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77059">
        <property type="protein sequence ID" value="KIC77059"/>
        <property type="gene ID" value="DB41_DH00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.242"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="4"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="28978" checksum="E3505F779BD045B7" modified="2015-04-01" version="1">MSKTQLMGILNATPDSFYDKSRFFEMTAAVARGHQMLAEGADILDVGGESTRPGAPAVSLEEEIKRVIPLIRRLKQELSIPISIDTMKPQVAAKAIEEGATWINDVGGFRDSAMREIAASAGVKLCVMHMQGTPQTMQKAPGYEASIVDYLKYWFSDIINTLIQSGVKEHNIVLDPGIGFGKTVAHNLEIIHNLAELKKLGFPVLIGVSRKSFMGKILNKSTDELLPATLAINSVAILSHVDFIRVHDIQAHRDIIDLLSVYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIP7</accession>
    <name>A0A0C1HIP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Leucine dehydrogenase</fullName>
            <ecNumber evidence="7">1.4.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ldh</name>
        <name evidence="7" type="ORF">DB41_CZ00050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.9" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383321.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77124">
        <property type="protein sequence ID" value="KIC77124"/>
        <property type="gene ID" value="DB41_CZ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.179"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050049">
        <property type="term" value="F:leucine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="PTHR42722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="6">
        <location>
            <begin position="143"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="179"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="359" mass="38765" checksum="ACA1D878451C00D1" modified="2015-04-01" version="1">MVQIKEVKIDGYKKVIEATDPGAHLHCMIAIHDTSLGPSLGGTRIYPYASSQEALEDVLLLAKAMTRKSAVAELGTGGGKSVILADPYQQKTEKLLLAFAEVVHSLQGDYIAAEDVGSDTKDMAIIRQKTPYVAALPTHTSSGDPSPFTAWGVYRGIQAVAQKLWGTPSVANKKILVQGLGQVGSKLANILFWEGAQLILCEANEARLEEHAAPMGAKTVGLYDYIHTECDIFAPCAMGGVITEEIVPHLKCKAIAGAANNQLASPLVGEMLLKKRILYAPDYVINAGGLINATAEFNAGGYNATAARDKVNHIYYLLLKLFDKAEKEDKPTTFVADEIAQYNLTNLIGQRKKPIDFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIR8</accession>
    <name>A0A0C1HIR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CW00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243753.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77154">
        <property type="protein sequence ID" value="KIC77154"/>
        <property type="gene ID" value="DB41_CW00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.146"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="739" mass="83106" checksum="9E06670C272BAFFE" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ29</accession>
    <name>A0A0C1HJ29_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">eno</name>
        <name evidence="13" type="ORF">DB41_CK00020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243729.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77274">
        <property type="protein sequence ID" value="KIC77274"/>
        <property type="gene ID" value="DB41_CK00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.16"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="139"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="372"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="443" mass="48589" checksum="61C722D4ED64571C" modified="2015-04-01" version="1">MSYIRSVKAIEILDSRGNPTLKVMITTDRDISAEASVPSGASTGQHEALELRDGDKRRFAGKGVQKAITHVNGPLAQILVGEHVFDQARLDRMMIASDGCENKSRFGANAILGASLALARAGALNAKLPLYRYIGGAHTHILPCPMINILNGGAHADNLLDFQEFMIRPIGAPSFHEAVRWGAEIFHTLKGILREEGHVTAVGDEGGFAPNLESNEIALEMIVLAIEKAGYRPGIDVSLALDCAASEFYDDSTHLYKEKKKQKRKIPFIERTAEEVVDYLENLVKKFPIDSIEDGLAENDWLGWQHLTKKLGHQIQLVGDDIFVTNPKFLSRGFDLNVANSILIKPNQIGTLTETLETIRLAQNNSYAAIISHRSGETEDSIIADIAVATNAGQIKTGSLSRTDRVAKYNRLLNIEDSLQSVCRYGDSNLYKCRTGFSSPSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ55</accession>
    <name>A0A0C1HJ55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sec translocon accessory complex subunit YajC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">yajC</name>
        <name evidence="11" type="ORF">DB41_CJ00090</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the YajC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77299">
        <property type="protein sequence ID" value="KIC77299"/>
        <property type="gene ID" value="DB41_CJ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.9"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133882" description="Sec translocon accessory complex subunit YajC" evidence="10">
        <location>
            <begin position="24"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC77299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="15918" checksum="6C15CD327FEB765F" modified="2015-04-01" version="1">MIKKMTGFSTLGFTLLNNTIAFAQEGTNLEIVPRDQGMTQTFVMIAIALIFFYLILWRPEQKRRKAIEEQRSALKKGDRVTAMGIVGTIVRIEENTVILKMYDGSKIEMLKAAITDVIAATEEEAKKADKEERKVEEKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ59</accession>
    <name>A0A0C1HJ59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
            <ecNumber evidence="6">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tpx</name>
        <name evidence="6" type="ORF">DB41_CJ00140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383037.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77304">
        <property type="protein sequence ID" value="KIC77304"/>
        <property type="gene ID" value="DB41_CJ00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.14"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="3"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="195" mass="22069" checksum="5FA2A1D7BCAE96A8" modified="2015-04-01" version="1">MGVLVGKQAPEFRAKAVIEGRIINTFSLMDFLGKNVVFFFYPLDFTFVCPTELHAFQEKIEEFEKRDTQLVACSVDSPYCHAAWLNTPKSKGGIQGLTYPIVSDMNRCIACDYDVLIQHEGIAYRGLFIIDKKGVVRHQVVNDLPLGRNVEEVLRMLDALVFIEENGEVCPANWQKGSRTMKPTSEGLEHYFTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKJ3</accession>
    <name>A0A0C1HKJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tyrosine-specific transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tyrP_1</name>
        <name evidence="9" type="ORF">DB41_HY00140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74988">
        <property type="protein sequence ID" value="KIC74988"/>
        <property type="gene ID" value="DB41_HY00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46997">
        <property type="entry name" value="PTHR46997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="422" mass="46134" checksum="A0C4C49120089ACE" modified="2015-04-01" version="1">MEKSHVPSKGTVLSAMFLVAGCCIGGGMLALPVATGVNGFIPSLVVMVICWIMMTITGLLLLEVSLWMEEGVHVDTMTHRLLGNVGRWISWILYLFICYASLVAYTAAGGHQLALAFGSIFDIPLTKELGCTIYILTFGLVLYLGSAIVGRVNAILFMAMLASYVALISIGMPEVQVTYLKYSHWTGFLLAIPLMLASFSYQTMVPSLTPYLKKNLKGLRLAIIGGTSITFMIYALWQCMMLGIVPVEGTHGLAQALIDGKPATLFLNEHVHGKYVASIAHFFAFFAVVTSFLGIALGLFDFLSDGLKIKKIGMGNVILGILIIMPTLVFATQFERVFVVALDSSGGYGDTILNGFIPVLMVWVGRYSKGYPAYFRVPGGKLLLSVVFIFFLLCLLLEIFVHTGYLSSVYEAYELIEKRIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKN9</accession>
    <name>A0A0C1HKN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_HY00390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75013">
        <property type="protein sequence ID" value="KIC75013"/>
        <property type="gene ID" value="DB41_HY00390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1432"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="232"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="488" mass="54734" checksum="4E23FACB44D80FDC" modified="2015-04-01" version="1">MEATIHNKKEDNDEEHGYTFSLLDSKRSHLDDVLNEKLEDAFHQHTSDIVLHDVAKIASQHDPIDMAHAVTRLPPQARVIVYENLPDLNAKIIFMINTSSSTRSAIFRQIDDSEIKSLIEKMPPDEAVWILDDMSDRRMRRVFDLLEPKKAQRIKELQKHDRHSAGRLMTDEFFAFHMNTTIGEVSAYIRDNPGIELTRRIFVLNDEGQLVGYVPGRNLIVNPHYLPLRQIMRPILQKVTVDVSRDEVVDVVERYKIPALPVVDENEHLRGVITYESVVEAMEDIADETIANIAGTAEDYREYEPILKRFLGRAPWLMVTLCAGLVSTGVMSHFYDRSWFALLPFFVPLITGMSGNVGIQCSTILVRGLSTGDISPGYKSEAISRELAIGLLIGLVFGLICGTVVYLLNYFGVHHLQADPLSLGITVSCGVFGACLAATMLGSFSPFFFVRFGIDPAVASGPIVTAFNDVLSTLIFFLFARLVYAFIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HM77</accession>
    <name>A0A0C1HM77_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flotillin-like protein FloA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yqfA</name>
        <name evidence="5" type="synonym">floA</name>
        <name evidence="6" type="ORF">DB41_HL00110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homooligomerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Membrane raft</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the flotillin-like FloA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385329.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75478">
        <property type="protein sequence ID" value="KIC75478"/>
        <property type="gene ID" value="DB41_HL00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1270"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01562">
        <property type="entry name" value="FloA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022853">
        <property type="entry name" value="FloA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12127">
        <property type="entry name" value="YdfA_immunity"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="339" mass="37051" checksum="7C39425F756879E6" modified="2015-04-01" version="1">MTHQLLALHLSSELYFLLILLALASLIILSILGKFLSFWFQAFVSGTPIPLFNLIGMSLRKIPLRVIVNARINLFKAGLKQVTVSDLETHYLAGGHVSEVATALIAADKANIQLDWRRATAIDLAGRDLRDAVQTSVNPKVIDCPSHGGYITGVAKDGIQINVRARVTVRTNIAQLVGGATEETIIARVGEGIVTAIGSSETHLHVLESPHKISQVVLEKGLDSSTAFVILSIDIVEMNLGENIGAKLRADKAESDKRIFQAEAEKRRAMAAAMEQENMAKVKDMEAKLIEAQSSIPMAIAESFRSGHIGIMDFTRYENILADTKMRKSIAEESDDRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMQ9</accession>
    <name>A0A0C1HMQ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">fabH</name>
        <name evidence="10" type="ORF">DB41_HJ00080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385303.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000120.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75608">
        <property type="protein sequence ID" value="KIC75608"/>
        <property type="gene ID" value="DB41_HJ00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1251"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="110"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="241"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="257"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="36307" checksum="D0BA00725C9B9FD7" modified="2015-04-01" version="1">MPIQPKARIVGMGSFLPERILTNQHLEEMVETTDEWIVSRTGIKERRIAGTHEPPSLMGFYAAQKALQESSVSAADIDMVLVATMTPDYITPSTAAIIQAKLGASSAAALDIQAACTGFLYGLSIAKAYIEAGIYRNILLIASEKLSTIINYKDRNTCVLFGDGAAAAVISNQGKGFSLDAFCLGSDGEVAELLMIPAGGARQPSSIETVTQELHFLKMEGKEVFKHAVRRMGAAAKECLVKAGITEGEIDWLVPHQANIRIIEALAKSFNLPSERVYKTLHKYGNTSASSVAIALEELKSENQILQGEKLLLVGFGAGLTWAAAIITQIDDLSSSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMZ3</accession>
    <name>A0A0C1HMZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HH00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243934.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75718">
        <property type="protein sequence ID" value="KIC75718"/>
        <property type="gene ID" value="DB41_HH00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133269" evidence="1">
        <location>
            <begin position="26"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="569" mass="64998" checksum="857CF8729F285989" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNS8</accession>
    <name>A0A0C1HNS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GV00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000107">
        <property type="protein sequence ID" value="KIC75948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75948">
        <property type="protein sequence ID" value="KIC75948"/>
        <property type="gene ID" value="DB41_GV00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="8002" checksum="7B823161C2CEFA39" modified="2015-04-01" version="1">MMLRENHISEEHKVGNIEACMRGRPTRSSEEVFVMKRARRGWNCSIQLNKSSRNTRNLWGWRKGWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ89</accession>
    <name>A0A0C1HQ89_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_GH00010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000093">
        <property type="protein sequence ID" value="KIC76363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76363">
        <property type="protein sequence ID" value="KIC76363"/>
        <property type="gene ID" value="DB41_GH00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="19"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="132" mass="14006" checksum="0954597B8B1F4C62" modified="2015-04-01" version="1">MACSNVISMLIILVNDKKLEIGILRSMGASSASIASIFGFCGMTMGLAGSVIGIGAALLTLRHLELLVTFLSRLQGHEAFNPLYYGDSLPNEVSMEALLYVISFTALISLFSGLVPAVKASLLRPSTILRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS53</accession>
    <name>A0A0C1HS53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0111 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DS00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383612.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76923">
        <property type="protein sequence ID" value="KIC76923"/>
        <property type="gene ID" value="DB41_DS00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.377"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002727">
        <property type="entry name" value="DUF47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36536">
        <property type="entry name" value="PTHR36536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00153">
        <property type="entry name" value="TIGR00153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="25955" checksum="1673331B8EE1765A" modified="2015-04-01" version="1">MLKTILGIFGRSPFAPLQSHMEIVNSCVQMLPSLFEAMKNKDYAAVEKIAEKISEQEHHADLAKNHIRNHLPKNIYLPIERQHLLDILSLQDDIADKAQDLGVLSNLKPLEILPSFENEFNLFLVKNMESFEEARRIINELHELIETSFGGVEAEKVRSMVEKVAFKEHEVDILQRKLLKNLYQSENEMTHSTFYLWQKIFGTTGALSDISEKLANRVRLTLELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSX1</accession>
    <name>A0A0C1HSX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CX00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77143">
        <property type="protein sequence ID" value="KIC77143"/>
        <property type="gene ID" value="DB41_CX00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6486" checksum="525ED73B42935C0C" modified="2015-04-01" version="1">MDNATFHKSPTTHELIKKAGCEILFLLPYSPSFNPIGTFWANFKKIVAANLNKFSTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSZ2</accession>
    <name>A0A0C1HSZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sporulation-specific N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cwlC</name>
        <name evidence="2" type="ORF">DB41_CV00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243751.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77173">
        <property type="protein sequence ID" value="KIC77173"/>
        <property type="gene ID" value="DB41_CV00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.138"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="1">
        <location>
            <begin position="128"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="255" mass="28287" checksum="E86E1F4B3A2225B4" modified="2015-04-01" version="1">MMKNFQNCLWIFLLLSLGGCRCPSKELSSQPAVHSAPVAQLPAESMMGVKPPIKDIKKPKLSKAALIVIDAGHGGDDFGTRSLSQPKYHEKFLNLTTSLALNEFLQKMGYRTRLTRSNDEFISLQKRANFANDQGADLFVSMHYNSAPAKQADGIEIFYYKSEINKKRSTQSSQLASSILAQVIQATKAKSRGVKEGNFAVIRETKMPAVLIEGGFLTNEKEMNKIKEPAYIKRIAWGIAKGVEAYLNERSVSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKW6</accession>
    <name>A0A0C1JKW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AE00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71930">
        <property type="protein sequence ID" value="KIC71930"/>
        <property type="gene ID" value="DB41_AE00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5463" checksum="45AACB03813DD07C" modified="2015-04-01" version="1">MLLGYLFLDEALTAGGIFSAGLILLGMLIVNEVISFKWRRLRFFQQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLI4</accession>
    <name>A0A0C1JLI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase, IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BF00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000226">
        <property type="protein sequence ID" value="KIC71441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386973.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000226.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71441">
        <property type="protein sequence ID" value="KIC71441"/>
        <property type="gene ID" value="DB41_BF00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2286"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="2">
        <location>
            <begin position="4"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="128"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="541" mass="61955" checksum="BA4B4DAFCC651EBD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM22</accession>
    <name>A0A0C1JM22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KO00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72325">
        <property type="protein sequence ID" value="KIC72325"/>
        <property type="gene ID" value="DB41_KO00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1992"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="418" mass="47062" checksum="54167FAC112D54B0" modified="2015-04-01" version="1">MRLSKFPKLSLVLYFYLWPLLMEARLLTLDEATQRALTYSPAVAIVDTTWKVRQAEEYQANFLPNPVVSVEIDKANLIGKEKKRAGDRGFSCNLSQAIELGGKRHLRKQTAGLQTSLAFKEIEVIKLEASCQVEKAFIEVAAAQEYLRFAQELQLSAQEVLFSTSAKVEGGKISSLEGKKAKLSVLTAHLALEKARNNFENSKKKLALIWGDSRPDFTSVDYNLLEITLVEDLAAFIAEQNDNIATKQWELQIANADLMIASEKAQRIPNLVVTAGYVNSGEDGEGLLLGFSMAIPIWDRNQGNISKAKHLLNQLHNKRNKDNLQVRLQLEAEYAQLLTSYQEGLLYKNDVLPIAIAAFEGAKQEYLQGKSDYLEMLDAQRTLFDVHDKYMHALVDYHQRKVELNRLVRVGYANTQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN00</accession>
    <name>A0A0C1JN00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71951">
        <property type="protein sequence ID" value="KIC71951"/>
        <property type="gene ID" value="DB41_AE00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4627" checksum="5CCA4569E06BC15B" modified="2015-04-01" version="1">MLENFALILAEKQSFRFYAFLLNQKLYIFKASEPANLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP79</accession>
    <name>A0A0C1JP79_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MAF_flag10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JU00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000177">
        <property type="protein sequence ID" value="KIC73025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73025">
        <property type="protein sequence ID" value="KIC73025"/>
        <property type="gene ID" value="DB41_JU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002826">
        <property type="entry name" value="MptE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01973">
        <property type="entry name" value="MAF_flag10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAF_flag10" evidence="1">
        <location>
            <begin position="211"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="945" mass="108386" checksum="2DCDFE34A80FE73E" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPU0</accession>
    <name>A0A0C1JPU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative metallophosphoesterase</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KJ00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244051.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72536">
        <property type="protein sequence ID" value="KIC72536"/>
        <property type="gene ID" value="DB41_KJ00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="59"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="326" mass="38017" checksum="AD517734032E4E14" modified="2015-04-01" version="1">MKKNHRLNKFIINLPNFFWDLWCCLSIIGIWPRFIENKLVSKTFKRFKIPYLPKDLQGLKIAQFSDLHLHPQVSQRFLKKIKRKIESFQPDIIVFTGDFLCFSLSRDLMRLEQFFASLKAPYGCFAVLGNHDYNAFVSVNEKGEYDVLPSSTGSINKVLKRLWTNKILVRRVTDHARAVKPHEELEKALKNTHFRLLKNESLLVPIKGSFINIIGLEEYSTGRHSPRLAFQTVDPRFPGLVIAHNPDIVPHLLNFSWDVILCGHTHGGQVNLPWLWKKFTLMENPYLKKGLICMQNKWIYVNRGIGSIMPFRWFSMPELLLLTLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPW6</accession>
    <name>A0A0C1JPW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JM00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73250">
        <property type="protein sequence ID" value="KIC73250"/>
        <property type="gene ID" value="DB41_JM00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="91" mass="10711" checksum="BA167BF67DAD24A4" modified="2015-04-01" version="1">MSCYCLSLLQAFHLVEVELTCHQWKNLAHDETLWKNLYQKHFEIYGPDEGPFKESYFAAHRVKREHEKLMAFLGSIKHVHNLELAKCIGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRU4</accession>
    <name>A0A0C1JRU4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Poly(A) polymerase I</fullName>
            <shortName evidence="5">PAP I</shortName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">pcnB</name>
        <name evidence="11" type="ORF">DB41_IX00040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000155">
        <property type="protein sequence ID" value="KIC73880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_044881749.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000155.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73880">
        <property type="protein sequence ID" value="KIC73880"/>
        <property type="gene ID" value="DB41_IX00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1692"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004652">
        <property type="term" value="F:polynucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006378">
        <property type="term" value="P:mRNA polyadenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00957">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010206">
        <property type="entry name" value="PolA_pol_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025866">
        <property type="entry name" value="PolyA_pol_arg_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12626">
        <property type="entry name" value="PolyA_pol_arg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01942">
        <property type="entry name" value="pcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="8">
        <location>
            <begin position="36"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="10">
        <location>
            <begin position="183"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_arg_C" evidence="9">
        <location>
            <begin position="325"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="396"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC73880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="49337" checksum="05F76798A9835F00" modified="2015-04-01" version="1">MQAKIFHATDHEIEHHLIDKDALYVINRLKEAGFKAYLVGGGVRDLLIKKTPKDFDISTSAKPEQIKQLFGRSCLLIGRRFRLAHVRFGPKILEVATFRSGENDSDLIIQDNVWGTPEEDVLRRDFTINGLFYDPTNHSVIDYVGGWEDIHQRILRTIGEPSTRFKQDPVRMIRLLKFQARYNFTVVPEVQTALLECKKELIKSSPARILEEIFRMLESGYSSSFFHLMSQAGLLELIFPCLAHFIQSHQGNEIYRYLTTADQINLYSKRTLDRSLLTSNMLFPILEQEIKTQYLDKGRHPHMGEITMLTSSLIKGFVTSSFSHFPRRHSAVMNFILSTQYRLTPFSGKRHLRTKLVHNKEFEASLIFLKIRASIQPHLQEAYIYWRDQYKNAGRSSQVNRYSHPPKKRRYGRPPQPQKKDVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSW6</accession>
    <name>A0A0C1JSW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JG00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73571">
        <property type="protein sequence ID" value="KIC73571"/>
        <property type="gene ID" value="DB41_JG00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1741"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="109" mass="12926" checksum="80EBBC351EF95786" modified="2015-04-01" version="1">MASFIVIYDSCVLYPAPLRDLLMRFALTDLYQAKWTKDIHCEWMRSLLKNRSDLTKERLEMTRAKMDLHVKDCLVFDYEELIGSLKLPDPDDRHVLSSHQSKRTNYCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSZ5</accession>
    <name>A0A0C1JSZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IR00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244001.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74235">
        <property type="protein sequence ID" value="KIC74235"/>
        <property type="gene ID" value="DB41_IR00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002133981" evidence="1">
        <location>
            <begin position="22"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="226" mass="25368" checksum="0F61EF2C365667C6" modified="2015-04-01" version="1">MKNLFSLLSFCLSIVAFPCLHGDCRGKIDVAPTFVHLDIVNFGKTVKTMDLPTIKIDANALVYKGLCIRPGFMYGSNRGTLLTTGCGLGFTIPSQRWCFTPAIGANYTQLKTKIPLKIADFKLIAKEKFRSWSPYISIEVFYRIAKGCRVGLMVQYAWSRSHTTIKSMGTDKSKSNAKGPSYALLIEKDLHEHWSLNLGFAYNISLTREKHGLRGYGMKTGLAYWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JT36</accession>
    <name>A0A0C1JT36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_JE00020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000162">
        <property type="protein sequence ID" value="KIC73601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73601">
        <property type="protein sequence ID" value="KIC73601"/>
        <property type="gene ID" value="DB41_JE00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1726"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC73601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="13560" checksum="CFEFDF5A34101312" modified="2015-04-01" version="1">MLPALPAEEMILRLLLSGLLGGLIGFERERLSWVAGLRTHMLVCLGSTLIMLVSQYAFHEVVHEGLINLDPSRVAAQVVSGIGFLGAGTILFLKKCDSRSDNSSKLMGRGGSWSSYWRRALLGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV72</accession>
    <name>A0A0C1JV72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385785.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74960">
        <property type="protein sequence ID" value="KIC74960"/>
        <property type="gene ID" value="DB41_IB00930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1527"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="18069" checksum="39ACE9F975E1B347" modified="2015-04-01" version="1">MQSFPPTVILRHHKENLKKCSLRGLEGVEDFHFYTYPKSILPSLAGYTMLTLEAPVLSLEDAGQGLFILDSTWRYAEKMLKFVERHADLPKRSLPPHFRTAYPRRQEDCVDPARGLASIEAIYVAYTLLGRDTTQVLNHYHWKEDFLKINGFEKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWF5</accession>
    <name>A0A0C1JWF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AV00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71562">
        <property type="protein sequence ID" value="KIC71562"/>
        <property type="gene ID" value="DB41_AV00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_5" evidence="2">
        <location>
            <begin position="50"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="238" mass="27253" checksum="92337EF9FD0B9424" modified="2015-04-01" version="1">MALKQGNSHNSLFKIQWCWLTFCLMGILITNSICWAKFERAGLKSYKKMALSAMFRRAKIAWNRLLICSVRAVLRKHGITEGVLIIDDKDHSRSKNAEKLPHLHKIRDKKTSGYFCGQNIVFLQLVTKKFCIPVSFAFYSPDPVLTKWQQEVRTLKKLGISKEDRPKEPKRSLEYPKKYTLALQLLKNFACEFPAFKVTCVLADALYGNSLFLDGVEAIWPGVQIITQLKKESKSHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWT9</accession>
    <name>A0A0C1JWT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">UPF0053 protein YugS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">yugS</name>
        <name evidence="12" type="ORF">DB41_IB00390</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385721.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74906">
        <property type="protein sequence ID" value="KIC74906"/>
        <property type="gene ID" value="DB41_IB00390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="265"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC74906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="413" mass="47196" checksum="ED46C4E50C89CAEC" modified="2015-04-01" version="1">MISSLILIVVILLLTLASGWCSASEAALFSLSSTRIKSFKNSEDSRERLISRLLAQPRELLITVFLLNTIVNILLQNVISNAFTNAGGWLMAVGLPFVLLLVFGEIVPKYLGIQNNVKLSKHTAPALASLQRLLYPIKTFIIYILSPISRVFFFFLKKDAVISREELHHVLKKSEEAGILNHEERELIGGYLNLQDTNVREIMRPRQEILFYNKEDPLTKLIHLFVDKQCTRLPVCENGIENVLGIIDAKQYFLHRQAIHTSQDLKNFLWRPYYIPETTPSRTLLRRFEESGQEIALVVDEYGSISGLVTYEDIVEVVVGKIKDLRDQKVIFTQAGKDEIIASGKMELDEFNNYFETDLKSESMVTLGGWLTEQLGDIPKSGTKFENNTFLFQVLSADPNRIRRIYVRRLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWV0</accession>
    <name>A0A0C1JWV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74916">
        <property type="protein sequence ID" value="KIC74916"/>
        <property type="gene ID" value="DB41_IB00490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="299" mass="33850" checksum="E4ABCC0940C52899" modified="2015-04-01" version="1">MENMQALMIERLQIFTSASFIFIIFLLVAWKNDYFSSSRRLPESKQALAVKVWSCPFAIFFLLQILLVPASFKLWTFFYPHEEPFSPSSLTPEIQGWYTIYAIFVTGIGIGVYYFSLSKGNQEIILGACASKGSLYKLQDFFIACLSGVLSYPLVIATGQFIALLLMLTYQNVEIEQVAVQQIRMATSSLPLLMTLSVCIIFIVPIIEELLFRGFLQNGLKKYMTSKQAIGLTSLIFALLHFSSLQGWGNVELITSLFVLSCFLGFIYERQQSIWASVSLHAIFNAVNIMLIFYTKRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXV0</accession>
    <name>A0A0C1JXV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75890">
        <property type="protein sequence ID" value="KIC75890"/>
        <property type="gene ID" value="DB41_GZ00540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5428" checksum="4B8E15812462D4D6" modified="2015-04-01" version="1">MYKDFIKHFYLIIPISVVCSFISIPAFALVFTFNRWIVRFLKIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY34</accession>
    <name>A0A0C1JY34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_HN00030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75371">
        <property type="protein sequence ID" value="KIC75371"/>
        <property type="gene ID" value="DB41_HN00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1280"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="294" mass="32076" checksum="8647FE7FC1F28781" modified="2015-04-01" version="1">MAFRSFKVMLFIKDCFLIECFFYDELYGMSKHWLLSSPIGRSLASLGDYIVFITSVIAVSLRKPPQWVLIRDQLYEIGVLSLPVVGITGFSTGMVLAAQAYFQLSDKGLASATGLMVTKSMLVELGPVLTAFMITGRVGASMCATLGTMRVTEQIDALKSMSVNPLRYLVAPRFIAGLVMMPLLTIFSCLCGILGGYFIAVYYYGMAPTSFIDPLPINIQHFDFFSGLAKAFVFGLIIITISCYRGMTTRGGAAGVGRATTNSVVICYSVILVANFLITVALNSSYAYIEYFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYC2</accession>
    <name>A0A0C1JYC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GP00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384828.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000101.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76035">
        <property type="protein sequence ID" value="KIC76035"/>
        <property type="gene ID" value="DB41_GP00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="136" mass="15060" checksum="BAC800FA8831348C" modified="2015-04-01" version="1">MVKVTVLYTGELHCQVIREDPRAILETDAPVDSGGTGVSFSPTDLMASALATCIATTIALYAQRKNWNVTGMRLEVEKSMATQPIRRIGNIVIKIQIPQDFSLEQKQALERIAASCPVHHSLHPEVKVELIFCWDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYH6</accession>
    <name>A0A0C1JYH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_KQ00070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386477.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72242">
        <property type="protein sequence ID" value="KIC72242"/>
        <property type="gene ID" value="DB41_KQ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010764">
        <property type="entry name" value="DUF1347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07079">
        <property type="entry name" value="DUF1347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="955"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="989"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1023"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1079" mass="124333" checksum="E7C655A3DD68BCAB" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYQ0</accession>
    <name>A0A0C1JYQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_KO00100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386443.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72322">
        <property type="protein sequence ID" value="KIC72322"/>
        <property type="gene ID" value="DB41_KO00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="22"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="151"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="195"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="501"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="535" mass="60316" checksum="F92D7CEC335FC658" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ80</accession>
    <name>A0A0C1JZ80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ABC transporter ATP-binding protein YfmR</fullName>
            <ecNumber evidence="6">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yfmR</name>
        <name evidence="6" type="ORF">DB41_HG00060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75751">
        <property type="protein sequence ID" value="KIC75751"/>
        <property type="gene ID" value="DB41_HG00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1175"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="296"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="542"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="328"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="601" mass="68274" checksum="CFC83F60B4D88A9D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ88</accession>
    <name>A0A0C1JZ88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385174.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75761">
        <property type="protein sequence ID" value="KIC75761"/>
        <property type="gene ID" value="DB41_HG00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="10280" checksum="F94A3A7BC5BAB0E7" modified="2015-04-01" version="1">MLNVALSQGLISKVKARTAALLFSPYETLVKAAITTSQPLHIDATSWRHAATNEHWLVLRVGNVIAYALRLYQNGATLKIVIGQKIHCLESGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZD3</accession>
    <name>A0A0C1JZD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ygjT</name>
        <name evidence="7" type="ORF">DB41_KI00160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386348.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72572">
        <property type="protein sequence ID" value="KIC72572"/>
        <property type="gene ID" value="DB41_KI00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1912"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC72572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="307" mass="34976" checksum="29D550590A0E4171" modified="2015-04-01" version="1">MFENTISFWLLFNLAILIFIWLDFKFFHAKEKTLSIKTALIATSFWIGLALAFNLGIYWTRGLEDALSFLTGYLIEYSLSIDNLFVFLIIFSYFKVPERYTHKALLWGIWGAIVMRAFFILCGIALIQTFSWVIYLFGAFLIFTGVKLGKTSTAGNSPENNLIIKIFKRYFPLTEGYEGDNFFVKREKKLFATPLFLVLLAIETTDVVFAIDSIPAIMGITQDAMIIYSSNIFAVLGLRSLYFALANMLRLFHYLHYGLAIILIFIGLKMLLSGFLHFPIGVTLSVIFVILMASIGLSFLKNPHKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZF6</accession>
    <name>A0A0C1JZF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c551 peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ccp</name>
        <name evidence="10" type="ORF">DB41_GZ00200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="6">Binds 2 heme groups.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Binds 2 heme groups per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.5" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243919.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75856">
        <property type="protein sequence ID" value="KIC75856"/>
        <property type="gene ID" value="DB41_GZ00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1085"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026259">
        <property type="entry name" value="MauG/Cytc_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000294">
        <property type="entry name" value="Cytochrome-c_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="58"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="216"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="353" mass="39781" checksum="DAD5CC757ED6229F" modified="2015-04-01" version="1">MKLAQIAWIAFFLMGVAWSEVNVSDASKMNFLAEPQKLILPYGLPEIPWPKDNPYHAKKAELGRLLYFDTRLSSDGTVSCASCHAPSEGFSDRRPVSIGIKGRYGSRHSMTIINSAYQPLLFWDGRAKTLEEQSKGPIANPKEMTLADNPHEAHWQCQERVKNIAGYRLLFKEVFNNEECTIDDIAKALSTFERTLLSGNSPYDRYIKGDQSAMNAEQVNGYQVFLSKGCIDCHHGVNFSSGDFANIGIGMASSKPDLGRYEITKRDKDWGAFKVPILREIVRNHPYMHDGSLKTLEEVIEYYDKGGTPNPNLHPLMKPLHLKEEEKKALLSFLKALDGEGWQHIQSPSTFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZK0</accession>
    <name>A0A0C1JZK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bifunctional protein aas</fullName>
            <ecNumber evidence="5">2.3.1.40</ecNumber>
            <ecNumber evidence="5">6.2.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">aas</name>
        <name evidence="5" type="ORF">DB41_GX00040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.40" evidence="5"/>
    <dbReference type="EC" id="6.2.1.20" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000109">
        <property type="protein sequence ID" value="KIC75906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75906">
        <property type="protein sequence ID" value="KIC75906"/>
        <property type="gene ID" value="DB41_GX00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1060"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008779">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008922">
        <property type="term" value="F:long-chain fatty acid [acyl-carrier-protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="286"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="2">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="910" mass="101502" checksum="93156574EF085A6E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZP4</accession>
    <name>A0A0C1JZP4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="2">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">parC</name>
        <name evidence="6" type="ORF">DB41_KD00120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386295.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72712">
        <property type="protein sequence ID" value="KIC72712"/>
        <property type="gene ID" value="DB41_KD00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1870"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="5">
        <location>
            <begin position="2"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="633" mass="72109" checksum="A84F9B3E4E62F2B4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZR0</accession>
    <name>A0A0C1JZR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GC00320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384548.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76465">
        <property type="protein sequence ID" value="KIC76465"/>
        <property type="gene ID" value="DB41_GC00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1299"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1307"/>
            <end position="1332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1351" mass="149883" checksum="0709CF6C808B9DB4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZU3</accession>
    <name>A0A0C1JZU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GU00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75971">
        <property type="protein sequence ID" value="KIC75971"/>
        <property type="gene ID" value="DB41_GU00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7715" checksum="12DA787ADBFA462C" modified="2015-04-01" version="1">MKEVKRNSIIKNPFFFLNSANVALFCFPLYLLKLFAVSIKKLCYRANVKMAVFKLIRPSFLKNGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0J5</accession>
    <name>A0A0C1K0J5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">recO</name>
        <name evidence="6" type="ORF">DB41_JV00080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RecO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386239.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000178.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73017">
        <property type="protein sequence ID" value="KIC73017"/>
        <property type="gene ID" value="DB41_JV00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1832"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2 4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3 4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="5">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC73017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="227" mass="26148" checksum="9EADF37B3F6D763A" modified="2015-04-01" version="1">MQISHTQGLILKVIDFREYDQIMTVFTPDKGIVKWIFKIRKPSKTSPRVKISPLMQGEFTYSETKGEIWKCRELIIYNYYLKLRGDYNLLESAGRMINTVIDSQPLHKPAPKLFKQLITYLEKIPFTTNLPALELSFILKILKNEGVANTHLQCSVCQSPLQSLYIWQGEHFCAMHTPAGALLFNEDETLAWMQLAACSSFSQLNTICIPVHLPHKAHQLFKILVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0K7</accession>
    <name>A0A0C1K0K7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76700">
        <property type="protein sequence ID" value="KIC76700"/>
        <property type="gene ID" value="DB41_EY00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="8957" checksum="2E1E53C02ABC20ED" modified="2015-04-01" version="1">MFFFESEQLGWVTFQDQYFALSICDTGESTCRTSPQASLRTEQKSLDSHCSQLSKRSPHFYFFRCFRNNKRFCFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0L9</accession>
    <name>A0A0C1K0L9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_EY00260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383999.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76715">
        <property type="protein sequence ID" value="KIC76715"/>
        <property type="gene ID" value="DB41_EY00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="315"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="443"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="538" mass="61795" checksum="6329A3469BBF6681" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Q6</accession>
    <name>A0A0C1K0Q6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">truB</name>
        <name evidence="7" type="ORF">DB41_EO00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76750">
        <property type="protein sequence ID" value="KIC76750"/>
        <property type="gene ID" value="DB41_EO00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.535"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="5">
        <location>
            <begin position="35"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="6">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="240" mass="26504" checksum="60D8877B877ED7E7" modified="2015-04-01" version="1">MINRSASSMIPDPQGILLIDKPIGKTSFSLVAALRRILGVRKIGHAGTLDPFATGVMVLLIGRNMTKLSDRFLCEDKEYLAQVHLGEATDTYDCEGTITFQSPLVPTPSEIKAIIQDFQGEIQQIPPMHSAKKVNGKKLYELARQGKVIERQPATVTLQIEILDYHYPYLNLRVKCSKGTYIRSLADDIGKKLGCGAHLSNLKRTRSGPFKVEDCLDGSQLFIASPDAQEISKALFYPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K118</accession>
    <name>A0A0C1K118_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_3</name>
        <name evidence="3" type="ORF">DB41_JS00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000175">
        <property type="protein sequence ID" value="KIC73122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244034.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000175.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73122">
        <property type="protein sequence ID" value="KIC73122"/>
        <property type="gene ID" value="DB41_JS00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1814"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="658" mass="74908" checksum="DEE81014AFC1DBBA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K152</accession>
    <name>A0A0C1K152_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_JQ00030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244030.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73152">
        <property type="protein sequence ID" value="KIC73152"/>
        <property type="gene ID" value="DB41_JQ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1800"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="32"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="5">
        <location>
            <begin position="136"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="849"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="891"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="933"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="976"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1060"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1102"/>
            <end position="1135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC73152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1205" mass="136996" checksum="A24A23F85B54032C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1S1</accession>
    <name>A0A0C1K1S1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383516.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77005">
        <property type="protein sequence ID" value="KIC77005"/>
        <property type="gene ID" value="DB41_DN00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="209" mass="24488" checksum="D40C9C15FF9B5902" modified="2015-04-01" version="1">MIITLSATSFCILPFKACPQKTGHASQVFARICKICSYLGARIKKIALEIFYYLQEFYKDLKDDLSIWWFEKEDPIDTEARLECEKLRPEIEELKRKTLLLDTFINERPELKAKCLGYYHKYKHFFIKNTRGCGRTDFDLDNPVDQLNILAVEKLDLEYELDQRIDFITSFKEVYALFEKYVLEAEKAAKGAGNVFPLLLTQALENKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1X3</accession>
    <name>A0A0C1K1X3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DJ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000026">
        <property type="protein sequence ID" value="KIC77040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243771.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77040">
        <property type="protein sequence ID" value="KIC77040"/>
        <property type="gene ID" value="DB41_DJ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="8156" checksum="139CE26CAD0AD198" modified="2015-04-01" version="1">MKLNLLDISTDYLISQTQQATATGLSNLLDGQVSHDKITRFLNSDPGGSKELWQYIKKQVHHYSRKVCKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K254</accession>
    <name>A0A0C1K254_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">rbfA</name>
        <name evidence="2" type="ORF">DB41_EO00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383888.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76751">
        <property type="protein sequence ID" value="KIC76751"/>
        <property type="gene ID" value="DB41_EO00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.536"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="14065" checksum="F855C7B08122F100" modified="2015-04-01" version="1">MAKQRTDRLNSLLKEVISDVIRKDVRNPHVNELMTVTRVEITKDLHHAKVFVSVIGNQEEKDQTIHALETAAGFIAVTASKKVVMRYFPELHFKLDDSVDKHMRIEQLLEKISSERESRGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2A2</accession>
    <name>A0A0C1K2A2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsM</name>
        <name evidence="8" type="ORF">DB41_EI00160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383824.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76801">
        <property type="protein sequence ID" value="KIC76801"/>
        <property type="gene ID" value="DB41_EI00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.499"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="14205" checksum="42E0B291E3BA30F1" modified="2015-04-01" version="1">MPRVIGIDIPDNKRLEIALTYIYGIGRSLSNEIIEKLGFDHNMRAHKLTQDDIARINNLLQSEYMVEGDLRRQVQNNIKRLISIHSYRGTRHRSGLPVRGQRTRTNSRTRKGKRKTVANKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2K3</accession>
    <name>A0A0C1K2K3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383100.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77240">
        <property type="protein sequence ID" value="KIC77240"/>
        <property type="gene ID" value="DB41_CO00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="121" mass="13852" checksum="D7F4508B7E32F72C" modified="2015-04-01" version="1">MNYIYHNAPLIEHILESHDSIFFLSKGLSCLKKNPPLLEKKACSKEVSSQSTRNVELIERLKARIAIRKKNLAPTNSLLSTAACTICKKAVDILQQYQEERLCPLCLNRTIKKMRIKDILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Q7</accession>
    <name>A0A0C1K2Q7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76991">
        <property type="protein sequence ID" value="KIC76991"/>
        <property type="gene ID" value="DB41_DN00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4655" checksum="F2129E6AA27E04F2" modified="2015-04-01" version="1">MKKVKKKFSKCCEPKRARAIHANSPRLMASWYKMDSSPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2U2</accession>
    <name>A0A0C1K2U2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DL00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383470.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77026">
        <property type="protein sequence ID" value="KIC77026"/>
        <property type="gene ID" value="DB41_DL00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="623" mass="71346" checksum="A5317309BFF77DFC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2W1</accession>
    <name>A0A0C1K2W1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2OG-FeII_Oxy_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DJ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000026">
        <property type="protein sequence ID" value="KIC77041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383452.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77041">
        <property type="protein sequence ID" value="KIC77041"/>
        <property type="gene ID" value="DB41_DJ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2OG-FeII_Oxy_3" evidence="1">
        <location>
            <begin position="117"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="739" mass="83816" checksum="7121A0E35DDA2653" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K312</accession>
    <name>A0A0C1K312_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DC00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383376.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77086">
        <property type="protein sequence ID" value="KIC77086"/>
        <property type="gene ID" value="DB41_DC00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="233" mass="25898" checksum="D337B92C39A47A1A" modified="2015-04-01" version="1">MKINDKILSIPPYISTSWRHVKSLQMKGPFLVITLMGGESINIPNLKGEVIEQIFSAHAEYLEKSIDSQEDDPTLSQAMLNTDQGEVPFKLGIGSIDGMGNPLIHNPAQRDAPDIPKQILEKIAAIAKIISPEELNVLPKAELDCNCLHCQIVRTINIAVEPEMMTAMNAEEEEVKEEELVFQQWDVTQAGDKLFNVMNKLDTQENYRVYLGHPVGCTCGKSSCEHIVAVLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5G9</accession>
    <name>A0A0C1K5G9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA pseudouridine synthase YlyB</fullName>
            <ecNumber evidence="2">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ylyB</name>
        <name evidence="2" type="ORF">DB41_IJ00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385918.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74532">
        <property type="protein sequence ID" value="KIC74532"/>
        <property type="gene ID" value="DB41_IJ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1582"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="11"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="219" mass="24481" checksum="3293F63BB65D3DB0" modified="2015-04-01" version="1">MDPQILYEDNHLFVVCKPAGILTQPSGTQQKNLEDICKAWLKKTYNKPGNIFLEAVHRLDKSVSGIVVFARTSKALSRLNAALRQQQFRKVYLAIVEGLPEKSVDTLEHYLLHDAYQSLVVSGNRPGAKLCRLHYQVLKHANQTSLVEVILETGRYHQIRAQLAAIGKPIVGDAKYGSQKPCFSPGIALHHSELMFPHPTLGKSITLHATLPEEMLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5K7</accession>
    <name>A0A0C1K5K7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74567">
        <property type="protein sequence ID" value="KIC74567"/>
        <property type="gene ID" value="DB41_IJ00380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5868" checksum="7520041158A859A9" modified="2015-04-01" version="1">MRIGQQKNYYHWLLPLGSYLLFLSCSVSTPNSLIMLVSRRTIFFQPKGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K998</accession>
    <name>A0A0C1K998_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HH00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385227.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75732">
        <property type="protein sequence ID" value="KIC75732"/>
        <property type="gene ID" value="DB41_HH00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1223"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="443" mass="51244" checksum="A2A477A5A77852A1" modified="2015-04-01" version="1">MPTFTTRKNKIVLTDYNYRRDIENRLFMAELSILEVDVLQEIINGSLKTTLTTLADNLEIAPSKLRPILDKLAKSGLFQIQGDGVLVDKEMRKYYEAHIIKFDDDFRPDMEYLQGLLSKAPIHALPSWYAIPRSSDNIFNSIIEKFLFTPKIYERYLQDLVFDNPILSSIAKQVFAAPDYKISAGALIEKFGLTREQFEEYMLFLEFSLVCCLRYVKTQDVWEEVVTPFHEWHEFLLFVQNTNPVAIQDATPITAVYEKEFGFLNELNAFVKKLLKKSISLTQAPKDLLEIALLLEIAKQEKQKIVASAYTEDWLKKTRADQAIILYRQSLNRLIANEQFTSFSEKDLREVEKSLKNFAHGKWVYFEDYIKGCLAAVGSVLPTSLVNRGKRWKYSTPNYNEEEKQFIKLITCEYLMQAGMVATGYHQDKLCLCLTPFGRLSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9B6</accession>
    <name>A0A0C1K9B6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HG00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385159.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75752">
        <property type="protein sequence ID" value="KIC75752"/>
        <property type="gene ID" value="DB41_HG00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="114" mass="12363" checksum="2EFF92D249CBC9B9" modified="2015-04-01" version="1">MKKIVSLIVNSIAIFITANLLPGIRLSNFRNALGVALALGLINTFVRPFLLILTFPLTILTLGLSTLFVSAFCVMLASWIVPGFFVNDSFSALVFAVVVAIFNTLISLFIKKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB03</accession>
    <name>A0A0C1KB03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76307">
        <property type="protein sequence ID" value="KIC76307"/>
        <property type="gene ID" value="DB41_GK00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.929"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="389" mass="44931" checksum="339C106909B22699" modified="2015-04-01" version="1">MVSMTFFTKYKLFFVFPTLFVSFFYSLALFAEISPAREDTQGQTIQAIASLLFYIQEDIESTAQEDSPLSPLTFAPEEIEYLWARAIAFYPTLFPIKEAYEKAHYINDEGMLKRCEEEVRSIWLTLNDEPQSSAEPLNKTLAERTYNFKNISDNPLVNNKIKKELAPYLLPANSKITAIADQIFQTSRVTFNSQTLTEAGFNILYKQPRSFIIVAKHPSLPDYLIKLYFDTELRIKRNVPGWKWFARRCAGANLVRKVILKKNIQYFTVPQKYIYVLPSFHAPAKAAGVDPKVAILIVQDMQLVPKEQNYLAWRSKVTPEILNELYIIISRANGSSYRPDNIPYTLSGKFAFIDTEYPFRDPDFKSIRPYLSAEMCQYWDQLVKQGGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBK4</accession>
    <name>A0A0C1KBK4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">aroC</name>
        <name evidence="10" type="ORF">DB41_FU00070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384338.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76522">
        <property type="protein sequence ID" value="KIC76522"/>
        <property type="gene ID" value="DB41_FU00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.766"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="300"/>
            <end position="304"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="362" mass="38843" checksum="5BCD4828FC892E43" modified="2015-04-01" version="1">MASNSMGNIFRITTWGESHGPAIGVVIDGCPAGLLLQEEDINQALALRAPGHNIYTSPRQESDRCQILSGVFEGKTTGTPISIFIKNRDVDSSKYEPIQNLLRPGHANFTYLEKYGLFDYRGGGRSSARETACRVAAGAVAKKLLRHYDIQVIAYLLQVANIAAKVSFSSDLFESVYKSPIYCPDAKAAKPMQKAIMQAKEEGDSLGGIVELIAHNLPVGLGDPIYEKLEANLAKAMMSLPATKGFEIGTGFQAAKMPGSTHNDSFQHQQGKITTATNHAGGTLGGISTGMPLIARVVFKPPSSVMKEMETVNRQGEAATFKLPAGSRHDPCVAIRAVPVVEAMAALVLADALLMNRLSRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBT0</accession>
    <name>A0A0C1KBT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epimerase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_FK00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384245.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000072.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76582">
        <property type="protein sequence ID" value="KIC76582"/>
        <property type="gene ID" value="DB41_FK00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="250"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="301" mass="32794" checksum="8FC7F530E5B50268" modified="2015-04-01" version="1">MKILIADASGFIGKNLALALMQAGHDVKILVRKNTGLANNEISWAPEKGAISDNDLEGIEGIINLAGDNIFKGRWTEAKKRSIIESRLQATRTLASCLLRLKNPPKLYINASAIGYYGNRGDLLLTEESSNGTGFLAHVCEEWEKATQDLETLDVRVACLRFGIVLSTKGGALAKMLLGFKWGIGGRIGSGQQYMSWVSLEDVLAVFLHILKTEKLKGPINVVAPHPVTNHVFTKTLGKALGRPIILSLPTLVLRILLGEKADELLLSSQRVSCSKLIDSGYKFLHSNLEKALPQLLAQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCL4</accession>
    <name>A0A0C1KCL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EH00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76822">
        <property type="protein sequence ID" value="KIC76822"/>
        <property type="gene ID" value="DB41_EH00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5123" checksum="6B9945407B4ADEB4" modified="2015-04-01" version="1">MKKAFKMNKLILILARVGLFLYLYPSASSYPLVTICQKGFTYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCR3</accession>
    <name>A0A0C1KCR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76862">
        <property type="protein sequence ID" value="KIC76862"/>
        <property type="gene ID" value="DB41_EC00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="5886" checksum="E8751ED2FF97BA72" modified="2015-04-01" version="1">MRKFCHKLLKQSKHFRAYLKDPAIPMTHDAAEESLRNPAMVCKVCLDSQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCT2</accession>
    <name>A0A0C1KCT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EB00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000041">
        <property type="protein sequence ID" value="KIC76877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383719.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76877">
        <property type="protein sequence ID" value="KIC76877"/>
        <property type="gene ID" value="DB41_EB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="355" mass="39538" checksum="AC8010A27333FF61" modified="2015-04-01" version="1">MQFDPYSDSQGFTESLLRHFSEVGSNMGEGNLAQKVNQAHVILIGETHNQATEKIHQLVTTLLVTHITDKATILVEGQAFNRSAKVLSSHLEEHVGKVNISSWDSLETWKFLDIFLGEVTDRGNKKMADAIKIYLDNPDNLGAMCTVMYRRMQHLTQVTDKLANYIEEWPSTRPNKEDFKTILKESASNLKTILQPLEVLQEKDEQTTITASEIAILPLKLLSQTLIFMQALGHTANDLLAMSHPSRNQAMVENISVALKSYEKVIVIAGRAHLSSSSSSGSLGENIHIAQGIQIVGNKLLSEASKNRDFNYLILETREAADDLPEIQALPEEMKEPLGSIIKGKEKKQKDPARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDW4</accession>
    <name>A0A0C1KDW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_CV00050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383251.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77167">
        <property type="protein sequence ID" value="KIC77167"/>
        <property type="gene ID" value="DB41_CV00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.132"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="131" mass="14484" checksum="F64752473EDCF379" modified="2015-04-01" version="1">MHKLNWRESLGWSEEILEEMRSAGYAYIRQGKYEIALPFFEALCVLDPESAYDAQTLGALYLQSNNAAKALKCFDKALKIEGDHSPTLLNLAKALFMLGKKEEGLKVANILKNEANAAISNVAKALILAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1T1</accession>
    <name>A0A0C1H1T1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AT00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000216">
        <property type="protein sequence ID" value="KIC71639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386839.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000216.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71639">
        <property type="protein sequence ID" value="KIC71639"/>
        <property type="gene ID" value="DB41_AT00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="8015" checksum="E8913363D215A136" modified="2015-04-01" version="1">MGIKKILESVSSFTELKPLACKAKVHVSFWGTRYITVLGYEGTLPIDALAGKVLELVKKKSSFRRNREGMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H281</accession>
    <name>A0A0C1H281_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_12</name>
        <name evidence="3" type="ORF">DB41_AJ00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000208">
        <property type="protein sequence ID" value="KIC71789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71789">
        <property type="protein sequence ID" value="KIC71789"/>
        <property type="gene ID" value="DB41_AJ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2169"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="476" mass="53664" checksum="A953810885526FA3" modified="2015-04-01" version="1" fragment="single">EEKRGLTLANYSSYLLNINRLLLWKMLPGGEEYLSREEIKHLPLEKKGELLRDWIEENCKNLSASVLSEAGLTYLPPEICQLSQLQELYLNQNQLTTLPTEIGKLSQLARLNLNQNQLTALPIEIGQLSQLQSLDLKESQITALPTEIGQLSELTHLYLNQNQLTSLPTEIGQLSKLQWLYLNQNQLTSLPAEIGQLSQLQTLDLNQNQLTALPAEIGQLPELTRLYLNQNQLTALPAEIGRLPQLKGLQLNQNQLTALPAEIGQLPELTHLYLNQNQLTALPAEIGQLSKLQVLHLNQNQLTALPTEIGQLSKLQWLDLNQNQLTSLPAQIGQLSQLQWLYLNQNQLAALPAEIGQLSKLTRLELNQNQITALPAEIGQLSKLQWLELNQNQITSLPTETGQLPQLQWLYLNQNQLTSLPAEIGQLSQLQLLYLNQNQLISLPAEIGQLSKLQTLELAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2C0</accession>
    <name>A0A0C1H2C0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AF00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386683.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000206.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71819">
        <property type="protein sequence ID" value="KIC71819"/>
        <property type="gene ID" value="DB41_AF00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="457" mass="51619" checksum="A093086AE6AA8CA6" modified="2015-04-01" version="1">MALTKYQEGSFRELFSISLPLMLSSFSMMLMLFVDRLLLAHYSTAALNSAVNASTLGWGLLFGWVVLTNITEVFVAQYHGARQLNRMGEPVWQMIWLSLFSFLFFIPMAIWGSEWFYGSSPETAMERTYMRWMLLFGPTFAAYAALSGFFVGQGQTKLITLLAIGANVINVFLDISLIFGIEGVVPSMGILGAAIATSLGSLFQMLVLFYFFLKKENREKKGTGNFYFRPLAFWQCFKIGSPGAMFALIEIMGWAAFYQMMTRLSEVHITIAGICQSLFMLLLFFAEGVSKAATTICGNLIGAKRTWFISHVLKAGIRIHLLFLLVISTLFAYFHPLLIDQFLPYATPEYRAFIEIKLMNCLYATLIYVFFEGIRWLLSGILTAAGDTTFLLIAGSLSVWILMVAPVYFFVVKIQASVEVALYFWLLFSIGTVIIYYWRYASGLWKSKSIILEKPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3M1</accession>
    <name>A0A0C1H3M1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KT00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000198">
        <property type="protein sequence ID" value="KIC72129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72129">
        <property type="protein sequence ID" value="KIC72129"/>
        <property type="gene ID" value="DB41_KT00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2048"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="260" mass="29435" checksum="525B4E1E55FDE90B" modified="2015-04-01" version="1">MGQLSELQWLDLSQNQLTSLPAEIGQLSKLQWLDLNQNQLTALSTEIGQLPELQELDLNQNQLTALPAEIGQLPKLQALYLNQNQLTSLPVEIEQLSQLGELNLSQNQLTCLPAEIGQLSELQVLHLNQNQLTSLPAEIGQLSELQRLELNQNQLTALPTEIGQLSQLRVLYLNQNQLTSLPARIGQLSNLLQLYLNQNQLTTLPVEMGRLSRLQELYLKQNQLTSLPAEIWQLSQLKRLELAANPLKDIPKKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6Q1</accession>
    <name>A0A0C1H6Q1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_JS00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000175">
        <property type="protein sequence ID" value="KIC73124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244035.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000175.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73124">
        <property type="protein sequence ID" value="KIC73124"/>
        <property type="gene ID" value="DB41_JS00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1817"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="603" mass="68135" checksum="F7CC92BFBC87D050" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H952</accession>
    <name>A0A0C1H952_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">glmM</name>
        <name evidence="11" type="ORF">DB41_IX00030</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000155">
        <property type="protein sequence ID" value="KIC73879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386074.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000155.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73879">
        <property type="protein sequence ID" value="KIC73879"/>
        <property type="gene ID" value="DB41_IX00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1691"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="163"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="264"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="390"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC73879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="455" mass="49807" checksum="44D3CBEE8D4E4CEA" modified="2015-04-01" version="1">MTKKRTKVFGTDGVRGRANYTPMTVEIALALGRAAGKIFRRHNGKHRVVIGKDTRLSCYMFENALIAGLCSMGVDTLMVGPLPTPGVAFITRAYRADAGIVISASHNAYYDNGIKFFSSEGFKLPDAWEAEMEELITTNSFEDSLPLEFDIGKNSKINDADGRYIEFVKATFPRRLSLKNLKIALDCANGAGYKVAPLVFRELDAQVFVYGNSPNGLNINDACGSLHPETVQKAVIDHRADVGIALDGDADRVIMVDENAQIVDGDTILAICARDLKKQGLLKNNKVIATVMSNFGFVKAMRAEQIEVICSQVGDRYVLQDMLKHEANLGGEQSGHMIFLDHNTTGDGLVCALQVLRIMIETDSKLSDLALIVQRYPQSCINVSIQSKPPLNELKNVQEAIANVEKMLGDAGRVLVRYSGTENICRVMVEGPKLKQVQQMALTISNSVKEEIGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBS3</accession>
    <name>A0A0C1HBS3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385606.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74874">
        <property type="protein sequence ID" value="KIC74874"/>
        <property type="gene ID" value="DB41_IB00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026336">
        <property type="entry name" value="P_estr_lig_assc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024173">
        <property type="entry name" value="Pesterase_MJ0037"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000887">
        <property type="entry name" value="Pesterase_MJ0037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04123">
        <property type="entry name" value="P_estr_lig_assc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="27"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="23916" checksum="1670D735F8B22B18" modified="2015-04-01" version="1">MITIKIREQTIQLLPQRAAYWEENKALIVADIHLGKAATMQRAGIAVPEGAMDQDLLNLKNIIEHTGAQRCIVVGDLIHAQNGLSEGVQSKFGEWLSIINCSVDLILGNHDQVLKNYMPASWNLQVHQEYLAIKPFYFNHFPITIENHFVWSGHLHPQILLKSRHDQLNLRCFQISDSLGVLPAFSDFVGGSTVTKNADNRIFALAGKKIIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBU7</accession>
    <name>A0A0C1HBU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385709.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74894">
        <property type="protein sequence ID" value="KIC74894"/>
        <property type="gene ID" value="DB41_IB00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="16119" checksum="FF0FE650DC6D3D2B" modified="2015-04-01" version="1">MENIYLARYHLQVLALILHIFKKTQEKKRKREAPAPSSEESSHASLSPHASHAEKIQAVRLEEINRAKKIRHTLSQKLQNQQNEESAAVFSTLPLPPPPQPHYYSQGILPLPSYPPPLFPPWHTQMHPSQPSNIYPQRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCK8</accession>
    <name>A0A0C1HCK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HV00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243951.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75139">
        <property type="protein sequence ID" value="KIC75139"/>
        <property type="gene ID" value="DB41_HV00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1354"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="89"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="164"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="189"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="220"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="242"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="264"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="314"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="339"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="364"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="414"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="473" mass="53063" checksum="EF13FBDFC78D248C" modified="2015-04-01" version="1">MKIDTFSNVGVFIDNTADYLPLISTLTNLMDIFQKCVYLPFKNKESISKSRYYTHLNKKSFRRCLILLIPIIGNIFIGMEDFTPRSFHDKKFILASVRKRGCKLYFASEQLKNDKEVVLEAVRQDGLALKYASQELRNNKEIVLAAVQRNGLALKYASPQLKNDQEVVLSAVKKDGLAFASASKELKKDHEIMVAAVEQNGWALKYASKELKSNKGLIHALVQKNGWVLRFASRKLQNDQAMVEAAVLQDGWALEHASAELKNNKEIVLLAVEQNGLALEYASQKLKNDKEVVFVAARNDGAALKFASHKLQKDKDFILATLQHNGLMLEYLSEDFQNDKSLVLAAALQNGLALKYASQELQNDKELVQGVVLKNGLALEFASEELKNNAEVILAAAMQNGLALKYASPELQNNKELVLLIVQKFGWALQYASLDLRSDKDVVLAAVKHFSQSIKYASHKLQKDMELIELSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCY2</accession>
    <name>A0A0C1HCY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KH00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000188">
        <property type="protein sequence ID" value="KIC72618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386329.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000188.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72618">
        <property type="protein sequence ID" value="KIC72618"/>
        <property type="gene ID" value="DB41_KH00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="458"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="692" mass="79434" checksum="A2073BFECA9287A9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD70</accession>
    <name>A0A0C1HD70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HO00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385384.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000125.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75359">
        <property type="protein sequence ID" value="KIC75359"/>
        <property type="gene ID" value="DB41_HO00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="130" mass="14740" checksum="B8C261952B20A7F6" modified="2015-04-01" version="1">MECPELAPVKVNDLWMKKCQLHTSGTTVSFALIFDNPYTQIEEVWIGNLGDLRAILGIGPDCQQLTTDARYRNEKEDLNMANKQLLTSIHLREGWVDKDKQNIHRVAGIVQPLRGIGHQDIKGFSSRPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD75</accession>
    <name>A0A0C1HD75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HO00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385391.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000125.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75364">
        <property type="protein sequence ID" value="KIC75364"/>
        <property type="gene ID" value="DB41_HO00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="88"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="236" mass="27194" checksum="96F1BB14C0AE6C8F" modified="2015-04-01" version="1">MQDFEIFPLSPSFKVHISRIQPPKRMSQATLLSIEEMWKKELLRTQGKLFNGKILCADHFDGKHLYGRFVEYKLYLAQVRDPTLIHELHLKPICVCGYTLAGNEILMGKRAEHVTDYPNYLELMPAGGIDPSALNEGHVDIIKQLKTELKEEAGIEEAMIHHILPSYLIVDTHSHAYEICAKILLDPAVPKKELSHDDEHTEVFWIKQDHLSTFVHQNRPLINPLSMQLLQLFLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEA0</accession>
    <name>A0A0C1HEA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385164.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75754">
        <property type="protein sequence ID" value="KIC75754"/>
        <property type="gene ID" value="DB41_HG00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="387" mass="44721" checksum="AB9713970544C9E4" modified="2015-04-01" version="1">MKGPVARDSIGRCTPGNDLYAMIRNPMARVTPVAKPVDTIRSSRLRLEREATAKIGKFMQNFLVVARAGKYIFLAFTLPPYLLLYGLPKWVVENTVPLLFYLSLKPFQMMHHKLRHALKSHEASKNAIHSIKNLFSHAFKHTAEYIQWIQRTSQALFVHLKHSMVALGYRLLQPYLPIMQRSIQAAEAVTKMLLQKTYQRGDKQAELARQFALLMWKIVKEEFAGSLNLYINDLKAKFNTFKKHLKKQIEKPRLEIQKFNDNLIHQLKRINETLQTLGLKIAKHAEIMTLTVVNTALPFIGWAKPQIQRSVNLFQAGRAKLNHHLTHLSSIMQNLTLSALEASRFSRHLIVNSVKDVFKAIVPRFVKQFFNPEGGFKQKKQQMLEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEI6</accession>
    <name>A0A0C1HEI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384959.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75849">
        <property type="protein sequence ID" value="KIC75849"/>
        <property type="gene ID" value="DB41_GZ00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10922" checksum="AA8AC6BF8CBA3A34" modified="2015-04-01" version="1">MYNFFEQAKLVNYEGIEGISREETHEKDHGRIESRYVCVGNVLDWLPQREKWHSQSMIEVRSGRTIGDKVEQAIRYYGSSRKAGSKKFAKMLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFY8</accession>
    <name>A0A0C1HFY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JG00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386127.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73568">
        <property type="protein sequence ID" value="KIC73568"/>
        <property type="gene ID" value="DB41_JG00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="14370" checksum="03CC1CB04DE37BD6" modified="2015-04-01" version="1">MIARSSYPILDEAFCAIQGFAGAHLVNAIKGAKILNPATAAICFAGIALTEKAIYKLSKRIVPGSTGFLGPIPSGAKNIVSYGLATYTTFKIMELAGLILSIPKGIVVIGAYCSAALVIGGIATIINQHSKSFDERLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HG71</accession>
    <name>A0A0C1HG71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JC00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000160">
        <property type="protein sequence ID" value="KIC73663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386110.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000160.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73663">
        <property type="protein sequence ID" value="KIC73663"/>
        <property type="gene ID" value="DB41_JC00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1718"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="157" mass="18709" checksum="40E590CBA599B15C" modified="2015-04-01" version="1">MDKNNDNTQTSKALPWYKEGLRFQCTECGKCCTGSPGYVWITELEMQAVAKLLKMSLEMFKKKYTRQRENRYSLIEKKNFNNEYDCIFLKDKKCSIYQERPRQCRTFPWWKENLASEESWKAAAQYCEGIHEEAALVPYEKIEQQLHLNQNLLIQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGC9</accession>
    <name>A0A0C1HGC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GE00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000090">
        <property type="protein sequence ID" value="KIC76419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243877.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000090.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76419">
        <property type="protein sequence ID" value="KIC76419"/>
        <property type="gene ID" value="DB41_GE00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002151152" evidence="3">
        <location>
            <begin position="24"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="188" mass="21478" checksum="1B69660A8114A6C3" modified="2015-04-01" version="1">MKKLNFALTILGAICLTSLSANAFCATFCATTPGEKLDNTLDKVQDKYENIKENVRDKSKDFGDKAQDKYEDIKDKTRDTAEKIRDKSKDLGDKAQDKYEDIKDKNKGTAEKIKDKAKDIGDKIQDKYEDIKDKVSDKTKNIADKVKDKVNKGARHAKKESHRARKHLKKAEKRAAKAEKKAQRRMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGM7</accession>
    <name>A0A0C1HGM7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <shortName evidence="5">AcCoA synthetase</shortName>
            <shortName evidence="5">Acs</shortName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetate--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">acsA</name>
        <name evidence="9" type="ORF">DB41_GA00130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243863.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76489">
        <property type="protein sequence ID" value="KIC76489"/>
        <property type="gene ID" value="DB41_GA00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.816"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01123">
        <property type="entry name" value="Ac_CoA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="8">
        <location>
            <begin position="38"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="6">
        <location>
            <begin position="108"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="7">
        <location>
            <begin position="546"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
        <location>
            <begin position="208"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="402"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="426"/>
            <end position="431"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="530"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="552"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="599"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="660" mass="74528" checksum="192CA35BAC492BAF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGP6</accession>
    <name>A0A0C1HGP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FX00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76504">
        <property type="protein sequence ID" value="KIC76504"/>
        <property type="gene ID" value="DB41_FX00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5072" checksum="0D3ACFA383616211" modified="2015-04-01" version="1">MLSLPRALHGGRAVAEVLNYTSLFNNFFALPSSMFIKINVAWACIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH70</accession>
    <name>A0A0C1HH70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bis(5'-nucleosyl)-tetraphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nudT2</name>
        <name evidence="3" type="ORF">DB41_FH00200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76639">
        <property type="protein sequence ID" value="KIC76639"/>
        <property type="gene ID" value="DB41_FH00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.674"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="16005" checksum="D5F913E44BAAA215" modified="2015-04-01" version="1">MATKKEYSYGIVPLAQLEDGWHVLLVQAHAGHWGFPKGHPDSQESAWEAAQRELFEETGLKVCKLLSDQTFEESFYFKFEGVLIHKTVIYYIAQVEGEVKRMEEEIKAVQWVPLSQAADCITFDQGKNICRQVVQVVSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHF1</accession>
    <name>A0A0C1HHF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_ES00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000057">
        <property type="protein sequence ID" value="KIC76744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383932.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000057.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76744">
        <property type="protein sequence ID" value="KIC76744"/>
        <property type="gene ID" value="DB41_ES00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.553"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="159" mass="18233" checksum="E34C7D170A164F32" modified="2015-04-01" version="1" fragment="single">KGFAIITGGGPGLMEAANKGAQMTQGKSCGLGVDLPFEAELNPYIDRKYRLNFRYFFIRKVMFIRYAQGFVFLPGGYGTLDELFEALTLIQTHKIHPFPIYLMGKDYWKGIIDWIKSTMLTQQCISENDLKLISLTDDPEEVANGIERHYQRNHTQKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHL7</accession>
    <name>A0A0C1HHL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243804.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76809">
        <property type="protein sequence ID" value="KIC76809"/>
        <property type="gene ID" value="DB41_EI00240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.508"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="322" mass="36341" checksum="D921AEC230B67CD6" modified="2015-04-01" version="1">MDFTREPIIETVITPKEGCKIVVRNSKNVGQEEYFVDALEVVSFGTAIFFRSLEKPKSFLVPANDYEILEVREARMVLKNVGLERSIKIGGGRETKAVKEMPIDKMDPAAMEESNVIAEEQTAANDNRAEKKRDRRRQQRRRRGREEQIKEDLGGTEAISSLEDVGQLDVASSLEGKVAGEGQPLAQPTVPFMSGLLPPPPTLISETIGKYKENILFKNAFYTREETKEDDEVQVLHSITEEFEGESEEVEEFFKEEQSELPPIIEPAPEVKPLSSEEQNSSFHSFWDDLGEPTSSPLPLTETNEIKEPLKEEPSSPQEQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIM0</accession>
    <name>A0A0C1HIM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74403">
        <property type="protein sequence ID" value="KIC74403"/>
        <property type="gene ID" value="DB41_IP00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="274" mass="31943" checksum="C455427B444D7EAF" modified="2015-04-01" version="1">MNKCTDKDPFLNRQALSLNNMMVAERGAGKWRRIIIKWNQICPHDSIARIQHCYAAVIHTKNMNIYGDDEKSLLAWKFGALTLLSPIFYIAKTIFHLFFPISIYKYYTLEKKNWEALKAKPHPLNLPPSLHQKQPKLIRLILKNCLDICRTPLYALTISITSLGTLILSLFNSNYLYEGREILGNLQLSLNWERQKPYYFETIAPCMLPIDNLQDVASRRSYTQRDTDYEGPPGTLVHGLNNLARCHVLYWKSFNKKEKTIEPYRSSFLEKKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ04</accession>
    <name>A0A0C1HJ04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CO00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77249">
        <property type="protein sequence ID" value="KIC77249"/>
        <property type="gene ID" value="DB41_CO00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="246"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="434" mass="50374" checksum="1A33A68A185ED8AA" modified="2015-04-01" version="1">MLELTKDPRTFQQAQDLLAKREERLLLRKFQTFSFEEIKDNLDEKGMECETEGIIDKETFEKKITDPEFRAFLLQNFIEDIDQTEDTINVMTRNSLQTLAELKVRSEKKFFNFKLISSNIELILACLSTTLAITLQVLALTGVIALASSSMALPGLGFFVLGIAIMGIGLYFFYRYKPHLFKCVIQGVGVRLEVFQLPAKIRSWQLNKQEGRIHTLKITSARYEQLAGLLEQQKTLEATAYPSELRKTLEKLHKETKKKIDELESYGEQTQLEKMMEELDRKHERQLKMLEKESQKQERLKRKVESWIGKEGKITRLQNRLKEAGSTDFAIANGLITQAEKKAMNVPLIIMEKILEPNSSFEFDEETQKILKEKMGIDYQALKKTADQVDKNALMDKLKDFFKMDDTELLALMKQQLNNLKAKKYINYLKEQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ13</accession>
    <name>A0A0C1HJ13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holliday junction ATP-dependent DNA helicase RuvA</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">ruvA</name>
        <name evidence="10" type="ORF">DB41_CO00280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a complex with RuvB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RuvA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383126.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77259">
        <property type="protein sequence ID" value="KIC77259"/>
        <property type="gene ID" value="DB41_CO00280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.62"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009379">
        <property type="term" value="C:Holliday junction helicase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14332">
        <property type="entry name" value="UBA_RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00031">
        <property type="entry name" value="DNA_helic_RuvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013849">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvA_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000085">
        <property type="entry name" value="RuvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011114">
        <property type="entry name" value="RuvA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036267">
        <property type="entry name" value="RuvA_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07499">
        <property type="entry name" value="RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01330">
        <property type="entry name" value="RuvA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46929">
        <property type="entry name" value="SSF46929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00084">
        <property type="entry name" value="ruvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="9">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="201" mass="22215" checksum="4345EA21E4C750FF" modified="2015-04-01" version="1">MIAYIKGALTQLTSLFAVIESGGIGYKILIPANLFAKLPSLQEEVLLYTAFVIRENSQTLYGFLNSEDRELFEALMNVTGVGPKMALSIIGHLSGRELQRAIHNHEIATISKVPGIGKKTAERLMIEMRDKIPAILLLDPEEHAVYPSTDPHAQKIKDAMSALINLGYNQMIAQQAIKKCLKEFPETIELSELITAALKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKM1</accession>
    <name>A0A0C1HKM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75003">
        <property type="protein sequence ID" value="KIC75003"/>
        <property type="gene ID" value="DB41_HY00290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1423"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="154" mass="17815" checksum="EC0508D29A8417DE" modified="2015-04-01" version="1">MLSCANIVDFRAGPQTVVNEQRQNPYIDAKMTYRLDKLVERQAEFNLDFPIFLEGGIGTDFEYSLEEVRRKVGSVPSNPVLLFGEPAYWRQKITSRFQLNYTTGTIKGSEWITNCFYCIQNAQQGLKVYREFFQNKLKIGKTGPIYEEGFCIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL14</accession>
    <name>A0A0C1HL14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042241884.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75093">
        <property type="protein sequence ID" value="KIC75093"/>
        <property type="gene ID" value="DB41_HW00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="183" mass="21537" checksum="E971547506192E81" modified="2015-04-01" version="1">MTSFNSEVSRTKALNAVKSEDSKETTEMELEQLVFLLLTERLNQLQQKSNDEFQELKKRQEEVVQMHKVLKLINSQTTDRSELSFDTSHDLTHHLKDAREKLGIDIQEGSIKNGKMIYTKDQRDRLIDNIRMTIDDYNTKNDMQMQTVNRLINERYESYQMARAILKPIHDDKMSKARAIMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN54</accession>
    <name>A0A0C1HN54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243930.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000117.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75768">
        <property type="protein sequence ID" value="KIC75768"/>
        <property type="gene ID" value="DB41_HG00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1196"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="337" mass="38194" checksum="34F6513F75DA5DBD" modified="2015-04-01" version="1">MGIWAKEKKYLCAAGLLAITRKAFTRIKEPSVSSKKAKVPLVDCLMSGLALFGLKFPSLLKFDQRKEEPIIKHNLLTLYKIEKVPSDTYLRERLDVISPSLLRGAFCKLFAHLPRGKVLENFLFLNNYYLLSLDGTGVFSSETIHCKHCCEKKHRDGSSSYYHQILAGSIVHPDCQEVIPVGPEPISNEDGASKNDCESNAAKRFIQAFRKEHPHLNVIVTQDALSANGPHLKELQQAKLHYIIGVKPEGNASLFEWMQGLDFEELTIKEKKGELNIRFINGVPLNDTHADLQVNFFESWINDSKQGKKHFTWITDLPINANNVYELIQEAKSEMEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN69</accession>
    <name>A0A0C1HN69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HF00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385134.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000116.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75778">
        <property type="protein sequence ID" value="KIC75778"/>
        <property type="gene ID" value="DB41_HF00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1164"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="25516" checksum="09D3D83F0D5BBE34" modified="2015-04-01" version="1">MQALTQTSSLDSRSCPDFLESHLPGQNDYDLSIPSNEGIKDAAKSVSEISQKINQLKEIKQLCEFIVKNVYLKGRIYVQYSRSLKGHTIARHILHTYLNHDFSNPKEAERICLKDIMQQIEQIQFLELSGAKLTNLPAYFKYLTGLQHLNLCANNLTSLPPELKELVNLQELNLNGNHSFEELPPFLDNMNLKVIKIGNTKVNKASVKLQGIIDPGAMIQTWIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN88</accession>
    <name>A0A0C1HN88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">ffh</name>
        <name evidence="12" type="ORF">DB41_HE00090</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="8">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385082.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75793">
        <property type="protein sequence ID" value="KIC75793"/>
        <property type="gene ID" value="DB41_HE00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1143"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54_N" evidence="11">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="9">
        <location>
            <begin position="98"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="10">
        <location>
            <begin position="99"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC75793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="442" mass="48493" checksum="D602CC6E33D0AFDC" modified="2015-04-01" version="1">MLGALTEKMRGLVSKLAGAKKLTAENISDAVSEVRLALLEADVNYGVAKTLIKRVKEKALGDEVIKAVTPGQQFIKIVHEELVSLMGGGEAELKLEGKPAIIMLCGLQGAGKTTHAAKLARYLKKKGLCKKPLLAACDLQRPAAIEQLLTLGQQIEIPVFSLPEEKDPIKVARHALEKAKKEEFDVLIVDTAGRLHIDEELMLQLEEIKKVLQPSEIIFVANATTGQDAVNSAAEFNKRMAITGSILTMLDGNARGGAAISIREVTGAPLKFEGIGEKVDDLQVFNPSSMAHRILGMGDTINLVKKAQEHISEEDAKNLEQKIRSATFTYEDYLKQIQAVKKMGSLKSLLGMLPGMSALKSLEIDEKEFFKIEAIILSMTPQERAESEELSVSRRKRIAKGSGTGMEDINKLVKSFKQAKQFFKNMPNMKNLEKMMGGSLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNH9</accession>
    <name>A0A0C1HNH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384975.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75863">
        <property type="protein sequence ID" value="KIC75863"/>
        <property type="gene ID" value="DB41_GZ00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="76" mass="8729" checksum="6BFD89199392A2F6" modified="2015-04-01" version="1">MGAPINNNFRDLYEDAHLMVSNNPLVSTPKPFDINATERAEKAKKDFKKNREGKKDKDEKDSEEEENKPLPRPMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNI4</accession>
    <name>A0A0C1HNI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpsU</name>
        <name evidence="6" type="ORF">DB41_GZ00320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384980.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75868">
        <property type="protein sequence ID" value="KIC75868"/>
        <property type="gene ID" value="DB41_GZ00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1097"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018278">
        <property type="entry name" value="Ribosomal_S21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01181">
        <property type="entry name" value="RIBOSOMAL_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6837" checksum="321559F909B4B51E" modified="2015-04-01" version="1">MSLVKVRIGEPIDKALRALKKRLDKEGVMKSVKAHRFYAKPSVKKRAKSKAALKYKRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNY4</accession>
    <name>A0A0C1HNY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GR00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75993">
        <property type="protein sequence ID" value="KIC75993"/>
        <property type="gene ID" value="DB41_GR00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="107" mass="12665" checksum="3A8958D60E90B299" modified="2015-04-01" version="1">METSAVKIKEKEAKMERQFQQGLSLTATILYDLINFFVNENQSFWANQLGKWGLWMASVDEIHLQEVLKTFYDKFFHNDDLNEGLFLEIVQMFLKRVQEKSALALER</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HP44</accession>
    <name>A0A0C1HP44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GP00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243905.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000101.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76038">
        <property type="protein sequence ID" value="KIC76038"/>
        <property type="gene ID" value="DB41_GP00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="448" mass="50517" checksum="ADC0BE8B18649BC0" modified="2015-04-01" version="1" fragment="single">MHPISSASIESLPNELLLPILEACAAPPLFSVCKRWHHLLASEVMPSLYKKIGKVHVSQGDISKQAFILDRIYKLDNRLSEGEKAKAIFKEAFTLAKSLAPAELEFKWKTQEKRCYTLANYSSYLLNINRLLLWKKLPSGKEYLRQEKIKYLPLEKQGELLRDWIKENCKSITALRLFGVGLTYLPPEICQLSQLQGLKLSHNQLTSLPTETGQLSQLQRLNLSQNRLTSLPAEIGQLSQLQRLDLNQNKLTSLSAKIGQLSQLQRLDLSQNKLTSPPAEIGQLSQLQRLDLGQNKLSNLPTEIGQLSQLQNLYLYLNQLTSLPTEIGQLPQLLWLELNHNQLTNLPAESGQLSQLQTLYLNQNQLTSLPGEIGQLSQLQLLELNQNQLTSLPAEIGQLSQLQNLYLNQNQLTSLPAEIGQLSQLQNLYLNHNQLTSLPAEIGQLPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR60</accession>
    <name>A0A0C1HR60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FI00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243842.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76603">
        <property type="protein sequence ID" value="KIC76603"/>
        <property type="gene ID" value="DB41_FI00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="349" mass="39245" checksum="71573B7FE259456E" modified="2015-04-01" version="1">MRKSKAPLFSEKFLIQSALTLISSLLLIGTALFHDVLWIKPTPVAEETPKFFSNQTGDQLENAYIAAISNAKKSVLLLIFSMTSEEVIDALRQKSQEGVPVKVICDAKACPYISKKLGPQVELIRRLGKGLMHIKILVIDDIECWIGSANFTSESLNMHGNLVVALKNEALAATIKEKASTLHEYDRKGEVTHHTYLAGDQELQISFLPDDKKASVRIKQLIREAKKSIRIAMFTWTRFDMAKEVVEAQKRGVNVEVVLDRSSSNGASAKIAEMLKSHRVKLFYSAGTALLHHKFLWLDEHTLEVGSANWTKAAFTQNDDCFLVLHPLTHEQRQHMQNLWKAIKADSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRI1</accession>
    <name>A0A0C1HRI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA 2-thiocytidine biosynthesis protein TtcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ttcA</name>
        <name evidence="3" type="ORF">DB41_ET00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383946.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76738">
        <property type="protein sequence ID" value="KIC76738"/>
        <property type="gene ID" value="DB41_ET00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.560"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="2">
        <location>
            <begin position="38"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="248" mass="27947" checksum="780FAF0F8C9F82D9" modified="2015-04-01" version="1">MTISLPIAQPPWSRLGKKLESTFRRALYDYQMLESNNKIAIALSGGKDSLTLLFLLKAISGKGFPELDIYAILVNGEFSCGAGVNVTYLKAICDQLGVHFIVKESKQKLETLECYSCSRERRSLLFEAAKSVGATTIAFGHHRDDNIQTLLMNLLHKGEFAGNLPKIYMQKYGITIIRPLIYIQEEDIRAFAEQYGFIRIMCRCPVGQNSMRKKVKELIKEIEILYPYASENIARASLLYGSHKAAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS48</accession>
    <name>A0A0C1HS48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DT00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76918">
        <property type="protein sequence ID" value="KIC76918"/>
        <property type="gene ID" value="DB41_DT00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5463" checksum="E543488A5CEA21D1" modified="2015-04-01" version="1">MLLKSLHALFFVECHKSLKSCFDPKEAFVVLAYKLNYLKESSLIFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSI4</accession>
    <name>A0A0C1HSI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DL00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77028">
        <property type="protein sequence ID" value="KIC77028"/>
        <property type="gene ID" value="DB41_DL00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="113" mass="13036" checksum="687F9C999E8A731A" modified="2015-04-01" version="1">MIGRKLAYHKHHLHKRFLCSLVAKRSSGSLFNHRLDYSLSPYLTKSHASLGKYLSESFSKFFVWLCHADALATLPHPKRLLQRNQRLCLLDALRLSFLISSCPSSLARLQMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSM1</accession>
    <name>A0A0C1HSM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DH00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383415.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77053">
        <property type="protein sequence ID" value="KIC77053"/>
        <property type="gene ID" value="DB41_DH00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH-domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="SSF48065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="484"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="677" mass="75319" checksum="5A6C60CEB303165A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSQ6</accession>
    <name>A0A0C1HSQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="10">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 14" type="primary">ileS</name>
        <name evidence="14" type="ORF">DB41_DF00070</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383402.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77078">
        <property type="protein sequence ID" value="KIC77078"/>
        <property type="gene ID" value="DB41_DF00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.232"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="12">
        <location>
            <begin position="17"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="13">
        <location>
            <begin position="677"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="10">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="10">
        <location>
            <begin position="591"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="594"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC77078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1040" mass="119628" checksum="B91F21B11446F20B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT51</accession>
    <name>A0A0C1HT51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CO00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383111.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77248">
        <property type="protein sequence ID" value="KIC77248"/>
        <property type="gene ID" value="DB41_CO00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="212" mass="23393" checksum="F90DB4BF4DA83E1A" modified="2015-04-01" version="1">MQPPLVRSQQALKSFSLSAPAPVADEHQVSRTDKHNSAIPSSSIEKIELSDSALVINRVEVLNEEEPYRAESEVIIAEVEQQLENAETLLLLESEPITTLAEQKNVYALESFIKKTEKRKKIEGHLGNAYKATQWAPDKLHKLALEPYGHIAPVIGIPPKLGEIVGNVILPVSIIRTVLRGVEIIGKGAVLIVQGLQYQQAKKTLKAESRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK42</accession>
    <name>A0A0C1JK42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pknB</name>
        <name evidence="5" type="ORF">DB41_AS00090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244120.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71655">
        <property type="protein sequence ID" value="KIC71655"/>
        <property type="gene ID" value="DB41_AS00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2212"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC71655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="521" mass="58981" checksum="CD318DE3BD010495" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM76</accession>
    <name>A0A0C1JM76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KN00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000193">
        <property type="protein sequence ID" value="KIC72385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386428.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000193.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72385">
        <property type="protein sequence ID" value="KIC72385"/>
        <property type="gene ID" value="DB41_KN00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="76" mass="8664" checksum="12B3BB375C2322AE" modified="2015-04-01" version="1">MQMSSPLDYNCSRLIIHYDASLDQVSSEMARIKREVYRLRGIIGAFDETMQDSAALTTGVMDAYLQELKKLEPNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMJ3</accession>
    <name>A0A0C1JMJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">wzm</name>
        <name evidence="8" type="ORF">DB41_KK00210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244059.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72495">
        <property type="protein sequence ID" value="KIC72495"/>
        <property type="gene ID" value="DB41_KK00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1957"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="32"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="278" mass="31774" checksum="F2CE2A1CD082B9F5" modified="2015-04-01" version="1">MNKPTKPFLLRINPHIRQTQYLKDLIDYRELLYFFAWRDILVRYKEAFFGIAWAVIRPLINMGIFALVFGQIAHLSSGNINYASFVLAGLLPWQLCSNAIVEGSTSILHHANLISKIYFPRIIIPTAQIAVHFADFLIGMILLFFFCFIVQPLNFATLMGLPIFIMLALLLSEGGSLWLSALTVKFKDCRFLIPFVVQIGMFISPVGYSSSEISSQWIWLYCLNPAVGIIDGFRWALFGFTYPHLVYSIATSTVVTLVLVITGFLYFRKMERSFVDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMY1</accession>
    <name>A0A0C1JMY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AE00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386646.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71931">
        <property type="protein sequence ID" value="KIC71931"/>
        <property type="gene ID" value="DB41_AE00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="247" mass="28846" checksum="1EE21D35C96DA9D0" modified="2015-04-01" version="1">MQIALLRNQRDFHLSTKTIFQEPFKQAYKNFSITFCNKAFYPDQLKPLSTSKKIVCLFTALIYCVPLVNTIIFVSKEILCSFKNKLQWEKYYENHPLNKLTDNNLKILKKSLSSAILSIDFDHSLKYAKTQECSLAELEFNSEGKLKNVYYGHSLSDEGYEGRGFNLKNDSFYVLLSIQISTSKAYNHNPYYLEADDLEYYKTHYPSRIQEALELMLDKLNNKYAELALVNFKKSQDDPHVCKVVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN34</accession>
    <name>A0A0C1JN34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase DDE domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KF00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000187">
        <property type="protein sequence ID" value="KIC72640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72640">
        <property type="protein sequence ID" value="KIC72640"/>
        <property type="gene ID" value="DB41_KF00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="10121" checksum="E39806FFB67B414B" modified="2015-04-01" version="1">MIIAIMFHKSDYTTFKDYSMRQVIPSLQKYFPHVLSYNKFLTLMKTCLFSLFVYSQACLGECTGISFIDSTLLAVCHTRRIHSHPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNI6</accession>
    <name>A0A0C1JNI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KV00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72091">
        <property type="protein sequence ID" value="KIC72091"/>
        <property type="gene ID" value="DB41_KV00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6274" checksum="D79FF14C6D756127" modified="2015-04-01" version="1">MNNQKIVRASNISCSLEIAILNSPNNNLEKAEVLRNELALRVAILNQRELSDKKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPN3</accession>
    <name>A0A0C1JPN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JQ00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73150">
        <property type="protein sequence ID" value="KIC73150"/>
        <property type="gene ID" value="DB41_JQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="81" mass="9119" checksum="069B79E78EB4B6D9" modified="2015-04-01" version="1" fragment="single">MRRLQAVVLYLMLAIFTFCLAESPGILQSYLSSIILNQKSYRLRLTLLFIITRAALVSETISQCGAKQSLYTEESLLLSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQH7</accession>
    <name>A0A0C1JQH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RF3_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JJ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000166">
        <property type="protein sequence ID" value="KIC73470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73470">
        <property type="protein sequence ID" value="KIC73470"/>
        <property type="gene ID" value="DB41_JJ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF3_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="8839" checksum="C690ACBE312F461D" modified="2015-04-01" version="1">MQYRLKDEYGVDTTVSSLPYKCSAWLLGDIKTFQKPSNSLIVQDRYNRPIALFTETWEKQYAVKQNLEHQLVDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQS1</accession>
    <name>A0A0C1JQS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative signal peptide peptidase SppA</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sppA</name>
        <name evidence="3" type="ORF">DB41_JH00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386139.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73545">
        <property type="protein sequence ID" value="KIC73545"/>
        <property type="gene ID" value="DB41_JH00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1748"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="2">
        <location>
            <begin position="136"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="343" mass="38087" checksum="87BEEB9FE8518D28" modified="2015-04-01" version="1">MKDSIIQSALRAFLIALFTVIGGCLAILLIIFGMSAFNTSTSTEPTKDFNIEVLANAEGKREAFSNQPVILKININGIVGLDKLDQHHISQMLIQSREGILKNNLVKGILLHIQTPGGTVTDADGIYRTLKAYKHQYNVPIYAFVDGMCASGGMYIAAAADRVLATDTSIIGSIGVIAPSVLNISQLLEKLGIQSLTLYAGKGKDGLNPLRPWHAGEENNYRELIDYYYNEFVNIMTANRPQLDKTKLIQEYGAKIFPAQQAKELGYIDESGVTLNEAISQLARQMSIEGPNYRVVQMQKETWISEIFKTQLKALNSPIKHELQISPAYDPRLLGQFQYMFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSJ6</accession>
    <name>A0A0C1JSJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JJ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000166">
        <property type="protein sequence ID" value="KIC73471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386153.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000166.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73471">
        <property type="protein sequence ID" value="KIC73471"/>
        <property type="gene ID" value="DB41_JJ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036679">
        <property type="entry name" value="FlgN-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140566">
        <property type="entry name" value="SSF140566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="21813" checksum="222D3CFDCF58DDC4" modified="2015-04-01" version="1">MHFSNRKNDIIRDELNEVKMIDEALKIAMSALVNVLRELLANMEEEQYAIMAQNAPAFQVIMNSREPLLNSMQAFRGTMVQEINKLKDLHPEHADLESDQERLKNLARLAGADNIELLTLRDQILALSEQMEKQNTYNKLLLGNQQNESETENYSHQYKPRLAARVKPQKSSILPKQILQTIERTAEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUZ7</accession>
    <name>A0A0C1JUZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243970.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74890">
        <property type="protein sequence ID" value="KIC74890"/>
        <property type="gene ID" value="DB41_IB00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1455"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="36"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="119" mass="13195" checksum="7CEED45DFFB3B21D" modified="2015-04-01" version="1">MKKVIKYEESSGNVFADLGIENPEEALAKAELARQIAKLIKKKKLKQKRAAEILGIAQPKISALIRGRLRSFSLERLIRFLNELGQDVSIMISPAKSASRGHTWMSESHSNKPIAALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV22</accession>
    <name>A0A0C1JV22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74920">
        <property type="protein sequence ID" value="KIC74920"/>
        <property type="gene ID" value="DB41_IB00530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4819" checksum="C58F0FE881ACF33F" modified="2015-04-01" version="1">MAEVKQESSVTKLFKFLAAPFVKIGQWLLACFWWIFKRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVA5</accession>
    <name>A0A0C1JVA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74990">
        <property type="protein sequence ID" value="KIC74990"/>
        <property type="gene ID" value="DB41_HY00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="98" mass="11385" checksum="4D94FDDFB5BA644B" modified="2015-04-01" version="1">MSFRYSNSSIYFVEQHLNYKACLLIGHFPKEKIPSQVLNDFQSIISFFSIQVLPVFGLRFLLLAEGLKDLYSEYKMMGRKIIYHKLPVSKEFLGSLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVC2</accession>
    <name>A0A0C1JVC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ybfL</name>
        <name evidence="3" type="ORF">DB41_BV00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000242">
        <property type="protein sequence ID" value="KIC71212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244132.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000242.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71212">
        <property type="protein sequence ID" value="KIC71212"/>
        <property type="gene ID" value="DB41_BV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="2">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="107"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="376" mass="43103" checksum="35660245B51A9FCA" modified="2015-04-01" version="1">MSEDDTVIMGFLKIVPDPRIERCKKYSLESILFIALTGMLCGADSFIEIVDVADANLEWLKKYVDLPYGIPAHDTVCRVFSLIDKNKFCECFSAWSQSLQKHSSSDIIAIDGKSLCGAYGESLKGMAHMLHAWSIENGLCIAQQAVRDKSNEITALKPLLEMLDLKGCIVTTDAIHSHKKTATLISERGGDYALPIKDNEKDFKEEIEILFTDAFKNEFKGCDADHFKTLEKEHGRIEERNYWVLDAADLPKSKEWSNLKSVGLCQRERTLKGKVTIEQVYYAMSFEVDAKRFARVARDHWQVENNLHWILDVVFEEDKQKYKDKTMAQNLSCLRKMALNLLKKDPRKASLQAKRLRAACNITYREELLKNLFIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVK0</accession>
    <name>A0A0C1JVK0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_BP00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000236">
        <property type="protein sequence ID" value="KIC71287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71287">
        <property type="protein sequence ID" value="KIC71287"/>
        <property type="gene ID" value="DB41_BP00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_3" evidence="3">
        <location>
            <begin position="39"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC71287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="176" mass="20236" checksum="19312DFBBDB06FD6" modified="2015-04-01" version="1" fragment="single">YKIRKKLRENGENFLNQLKKPTRKPTTRWVFFCFLGLQRQHARGPIGEKIYGAIAGRSFARESFIAAKYKSKILAPFCYTGTCNFLLFNFWLEKILIPELKAGQILIMDNATFHKSQATHELIKKAGCEILFIPPYSPDLNPIETFWANFKKIVAANLSKFSTLAQTIDYSFLSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVW3</accession>
    <name>A0A0C1JVW3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_Tnp_1_assoc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HT00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000130">
        <property type="protein sequence ID" value="KIC75200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385446.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000130.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75200">
        <property type="protein sequence ID" value="KIC75200"/>
        <property type="gene ID" value="DB41_HT00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032806">
        <property type="entry name" value="YbfD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13808">
        <property type="entry name" value="DDE_Tnp_1_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1_assoc" evidence="2">
        <location>
            <begin position="30"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="95" mass="10903" checksum="3A4A7E383895B7D3" modified="2015-04-01" version="1">MPRRKAIDKNFVDLQEEIDLERFREMVRSNFADFPDPRISKRCIYPIGYLFLITLSGYLAGCNTVAEIAHFAEIRASWFADLIGLKVAAPSYDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW47</accession>
    <name>A0A0C1JW47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS4 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BB00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000222">
        <property type="protein sequence ID" value="KIC71467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386966.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000222.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71467">
        <property type="protein sequence ID" value="KIC71467"/>
        <property type="gene ID" value="DB41_BB00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="7139" checksum="D31003819F38FABC" modified="2015-04-01" version="1">MDVEQLNSIREQLDEWINAFKAHLGRSERVHWYRLHIAGLILEGERKSIEPMAKRLPGGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW95</accession>
    <name>A0A0C1JW95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HO00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75365">
        <property type="protein sequence ID" value="KIC75365"/>
        <property type="gene ID" value="DB41_HO00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="526" mass="59907" checksum="83173399E6EC3FED" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWM3</accession>
    <name>A0A0C1JWM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IE00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000139">
        <property type="protein sequence ID" value="KIC74836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74836">
        <property type="protein sequence ID" value="KIC74836"/>
        <property type="gene ID" value="DB41_IE00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2419"/>
            <end position="2442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="2477" mass="286064" checksum="4AE5EBEF192EB1E8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWW5</accession>
    <name>A0A0C1JWW5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6444 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74931">
        <property type="protein sequence ID" value="KIC74931"/>
        <property type="gene ID" value="DB41_IB00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="2">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="8219" checksum="2F4716738216474F" modified="2015-04-01" version="1">MMKPTYEDLFILVQHQSQMVFEQEQTIKRLEKRILELEKMLNLPPINSSKEPSSERKKNRHSPKRGAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXH5</accession>
    <name>A0A0C1JXH5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">rpsO</name>
        <name evidence="7" type="ORF">DB41_HF00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385127.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000116.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75775">
        <property type="protein sequence ID" value="KIC75775"/>
        <property type="gene ID" value="DB41_HF00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1160"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC75775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="10383" checksum="512490B5CDC17ED2" modified="2015-04-01" version="1">MSLDKGTKEEITKKFQLHEKDTGSADVQIAILTERIAELNEHLKRSPKDHASRLALFKHVGLRRRLLDYLNSTDTLRYLSLIKKLKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXK4</accession>
    <name>A0A0C1JXK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_HW00230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75111">
        <property type="protein sequence ID" value="KIC75111"/>
        <property type="gene ID" value="DB41_HW00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="PTHR11616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="437" mass="48596" checksum="0E36F538F7FED94D" modified="2015-04-01" version="1">MLGVPMLMLEGLIGYTWKLPIVSAYNKVLGKKGKVLGWLSVVACLTIGAFYIVLTAYSAAYTYFAASKQIPSDSKSFFFQEFLKTTESIHQLGPLSFPVLIATVSMCLLTYLVMIRNVRDGIEKICTLFMPLLAFIMTAFAITTMFLPGGLDALRHYLSPDFSRLNDPTLWRDVFGQLFFSLSLGLGIIVGYSRHTDQKTNIAQAMFWVTLGDFAVSFISGLAIFGCLAHISHIQKVPFEQILSSDSTFEIGFILFPKILQSFGEHWAQMVGTIFFFCIFIAGITGVFSIAESIVGNVEKEFTLSRKKAVTVTMSALLGMAVLFCFGNASHIIDALAPMVLGINMLIGGIALIITFQYACPALREDAIWYNGSQASFFSVSLRYVGPLLLTIILFSNLWHEFHTLDLSSFIRWLWFTIALIVSVLMAYQRKCQPTHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY04</accession>
    <name>A0A0C1JY04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HR00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000128">
        <property type="protein sequence ID" value="KIC75336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385422.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000128.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75336">
        <property type="protein sequence ID" value="KIC75336"/>
        <property type="gene ID" value="DB41_HR00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1327"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="275" mass="30847" checksum="4DB57DB0E9A9C351" modified="2015-04-01" version="1">MTFDDLQLMFNRALALSLNKKKFLLVFTILALCGVLVVFFRGLALGANEWLMMSLTFLPIFLCAGFLLSTGIVLIRIYHDEIKKKQTSYTEILAKSWEIMIGASYFCIPIILSYLLLWMLLGLFFLLEEIPAVGPFFSAILAFGPFLINLGTLLLCILSLAILFFVTPVIALKGLNRIQVADILSKRMRGDIFSNIILSLIATFPLWCLAGLLILAAWMTGSVCFSCHNPLHAILQWFFTMIPFTAVLTPAVIFFFNFAAEAHVLMIRGPQRTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY08</accession>
    <name>A0A0C1JY08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GW00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384920.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75935">
        <property type="protein sequence ID" value="KIC75935"/>
        <property type="gene ID" value="DB41_GW00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="226" mass="26306" checksum="128E0004061C0A03" modified="2015-04-01" version="1">MRSPYHLQNNNSLVFQFMVSEYLAICQAFKSFEIAVQNNNYEAANMALIRLLGYQDKNLFPAFFGYADKGLLQQLQSSCQSFNLNDEDKKQPAQKLNLHAQKAYSLCYQVWKTVENRPLSPSSPLFELASPYIPKIQNFLNKIGRLIAKLFLQFEDDETILFFLLENHQIVDEVYKAPLVKKVFAKMFPQGLKTAEKYIIKQYSKRGYYHLLPQVLEAAKELQQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY41</accession>
    <name>A0A0C1JY41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HN00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75376">
        <property type="protein sequence ID" value="KIC75376"/>
        <property type="gene ID" value="DB41_HN00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="101"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="400" mass="46265" checksum="38C2860FFCAD22EC" modified="2015-04-01" version="1">MQENAALTTDIMDAYLKELEPPLEQRGISVIRQQIDTRIEGIRENCLENYRGLLDARELIIIEGQTIQLNAQIKGTLEHAYQQRLEESIHQLKEEFPLEDATNLEQMRAQLKEKFERYEDIFEKLFERKQQLTDQGYELQEAMEPELAKLRAKKQELQKDLKVTDLFIASQLGAVDYLKQEISKKWRWGRKHFVNTPSQVGFAPLHYAAYHNQREALQLLIDKGADLTLKDNEGYLPLHWAAEKGHHEIVQLLVRHRPSTINAKGRLDRTPLHRAVFCGKMETAHLLIKNGAHINAQTHEKNHCQTPLHFAVLQGNISMVLALTRYPELDILQQDIQGRTPLHYAIEEGLIDILDILLKHPSWQKAKVSTHAKLLESLLSIVPKRQAKEIKAQLLLNFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYC6</accession>
    <name>A0A0C1JYC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HL00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385334.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75481">
        <property type="protein sequence ID" value="KIC75481"/>
        <property type="gene ID" value="DB41_HL00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015209">
        <property type="term" value="F:cytosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030191">
        <property type="entry name" value="CodB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30569">
        <property type="entry name" value="PTHR30569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="313" mass="33865" checksum="C2064644F637B12E" modified="2015-04-01" version="1" fragment="single">MDNQRNWWQLSSIQIGGVICLPVIVIGQTLYQTYGFASSIAAILLGNAILLLLGLATTKMSCEKRKTTPLNATEYFGETGVTFFALTMCVSLVGWFAIQLNMMSLSVFDLLSLDKNQALPGVLSNLMLGSLITVAALYGIKSINFLSNLSLPLLIITLGYAFFTVEDAPPSAPSVPLSFAGISMVIALAIAFVIDLPTYYRHAKTSKDGFISISIIFVLALPILEIVGVYLAAGSSGGTILDVLKRSNGNFWNLWVALFLILAGWTTNNINLYSGAVCLEPLLKIKSEKLRTLLFGGVGTFLSCFNFLNHLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYN9</accession>
    <name>A0A0C1JYN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GN00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243898.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76095">
        <property type="protein sequence ID" value="KIC76095"/>
        <property type="gene ID" value="DB41_GN00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.966"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="472" mass="53278" checksum="4CFF8E91BBD4C860" modified="2015-04-01" version="1">MNPSSPITIEHLPNEILVPILKACASSSLFSVCGRWQHLLANEVMPSLYKQIGKVHVPQGDVNKQALILDKIYKLKTELSAVAKVNAIFKKIFSLGKSLSPLELEFKWKTEEKRYLTLANYSSYLVNINRLLIWKRLPEGNKYLDQEAIKYLPLEKKGELFRSWVESYGKDIISLKLQRIGLTFLPPEIGQLSKLQNLDLSNNQLASLPVEIGLLSQLQELILNRNLLTFLSAQIGQLSQLKMLYLNENHLTTLPAELGQLSQLQELILNGNQLTSLPVEIIGQLSQLQELILSKNQLTSLPTEIGQLSQLPHLNLNSNQLTSLPVEIGQLSQLKTLLLNSNQLATLPVAIRQLSQLQYLNLNNNQLTSLPAEVGQLSQLKTLLLNNNQLAMLPAEIGQLSQLKTLYLNENHLTTLPAEIGQLSQLKKLYLENNHLTSLPTEISQLPTRLKLFLNRNPLENIPHEIYERVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ70</accession>
    <name>A0A0C1JZ70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HH00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75731">
        <property type="protein sequence ID" value="KIC75731"/>
        <property type="gene ID" value="DB41_HH00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4489" checksum="0390806FAFE9553A" modified="2015-04-01" version="1">MRVFKPGKKIDLLNVFCIILFVELSTPTGGGQGLIKILTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZB4</accession>
    <name>A0A0C1JZB4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L31 type B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmE2</name>
        <name evidence="6" type="ORF">DB41_HE00120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385088.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75796">
        <property type="protein sequence ID" value="KIC75796"/>
        <property type="gene ID" value="DB41_HE00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1147"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00502">
        <property type="entry name" value="Ribosomal_L31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027493">
        <property type="entry name" value="Ribosomal_L31_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="111" mass="12682" checksum="BC758B7798A4273B" modified="2015-04-01" version="1">MKKDIHPKYQKILFVDSSTGHKFVCGSTLQPKQMDKFEGTEYPVYHLSTSSASHPFFTGSKALVDSEGRVDKFKKRYATAQSKVNNEEPEGKLEEQPKEKEAKKDSKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZL1</accession>
    <name>A0A0C1JZL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KF00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000187">
        <property type="protein sequence ID" value="KIC72642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386322.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000187.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72642">
        <property type="protein sequence ID" value="KIC72642"/>
        <property type="gene ID" value="DB41_KF00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6915" checksum="55E8143C555BC791" modified="2015-04-01" version="1">MPAAIRGYEEKLKNLSVELQFKATQQLTKQIENTSEEETNLHDLQMFLINRLRPHSPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZX2</accession>
    <name>A0A0C1JZX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">aroA</name>
        <name evidence="9" type="ORF">DB41_FU00050</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384334.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76520">
        <property type="protein sequence ID" value="KIC76520"/>
        <property type="gene ID" value="DB41_FU00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.764"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="8"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="428" mass="46312" checksum="E705F126EC88ACD3" modified="2015-04-01" version="1">MKTLIVRPSSLSGEMQIPSSKSQTHRAILLGSLGKNVSLVYQYLNSPDCLAMMKACRYLGAKITAHGDHLHIEGIGGEIWGAENVINAHNSGIVLRFISAIAALGTHPIVITGDESIRHQRPMHVLLKALEQLGVQAISTRGDGFAPVIIKGPLRPGRVVIEDGSDSQNISSLLMAAIFLKGTLELEVHQTGEKPWLDLTLDWLKRLKVPYENHGYKNFKVQGIGSYDGFVYAVPGDWSSAAFPIAAAIVTRSEVVLNNLSMHDLQGDKAIVNIFRQMGAGIEIDEQAHSIHVYPRASLKGITVDINDCIDALPILAVVACYAEGQTSIINAAVARQKECDRIACIATELNKMGALIQESHSGLCITGNPLKGASVFSHKDHRMAMALAVAGMGAKGETAIYHSNCIEKTYPTFVQDFKRLGAHIEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0L0</accession>
    <name>A0A0C1K0L0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383989.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76705">
        <property type="protein sequence ID" value="KIC76705"/>
        <property type="gene ID" value="DB41_EY00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="38034" checksum="0DB1FAAF5A0BE03C" modified="2015-04-01" version="1">MSAIISQRDVLPMHLGYALGSIIKKSDFLLPLKNKVRLNLEEELERANIEKVEVTNSPSDTETVKNEKQTRLNILNAKINKIKKDYSEVCSNISKLYESRNFFSTEEMLPIDPHYSKVKIVDERSFFSEKMSHLVFRKTDTTGTDLHKKIEMFVSQLFSQDAPSSLLSSSMLGTVTSSIENMLETESQIYLVGSFITLPRVRVMDPVAIRRKATISNALIEQAEQYYVLTEAVLGAVFLGCGKYISGSGQGDKEGGKESESLMSKVSMISYISQGAIPRPGKDAEDINMWNVYAQWKQVLLEDPLSGYPIGFKVRELQDVFSENKISVRRKEEADTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0M2</accession>
    <name>A0A0C1K0M2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
            <ecNumber evidence="1">1.1.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fabG</name>
        <name evidence="1" type="ORF">DB41_GK00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384670.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76296">
        <property type="protein sequence ID" value="KIC76296"/>
        <property type="gene ID" value="DB41_GK00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.918"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="237" mass="26180" checksum="EA5745FA6B9A2A93" modified="2015-04-01" version="1">MKWTLVTGGAKNLGAAICLELAKQGHAVAVHYNTSKEEAQLVIEKCSYYQVPVQAVQGDFSTFESTQRFIKEYQKHFAETKNLINNVGNYLLGSSLKTSICQWHDLFQTNLHAPYCLIKNLLPSIKKWKGSIVNIGVAGLNANRADTYATAYTVSKSGLLMLTKSLALELAADQVRVNMISPGYLEESMDLPHPITKIPMQRVGRRDEVAQLIGYLLSDQASYITGQNIEIAGGTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0W9</accession>
    <name>A0A0C1K0W9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">rplF</name>
        <name evidence="7" type="ORF">DB41_EI00100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383817.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76795">
        <property type="protein sequence ID" value="KIC76795"/>
        <property type="gene ID" value="DB41_EI00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.493"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="13"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="90"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="181" mass="19678" checksum="8051E5BEEA4851CB" modified="2015-04-01" version="1">MSRKGKAPIPLIKGIEVKLEDSTLTVKGPKGTLTREIISGIEVVIENDHLQVNLTAGHEKMSNYHGLYRSLINNMVVGLSQGFTKKLEMIGVGYRAVVQGQLLDLQVGYSHPTKLTIPEGLQVAVEKNTTIVISGSDPQQIGQFAAQVRAIRPPEPYQGKGIRYAGEYVRKKAGKSASAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1U2</accession>
    <name>A0A0C1K1U2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DM00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000029">
        <property type="protein sequence ID" value="KIC77020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383490.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77020">
        <property type="protein sequence ID" value="KIC77020"/>
        <property type="gene ID" value="DB41_DM00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="132" mass="14948" checksum="071F0B13E7EA7C4A" modified="2015-04-01" version="1">MDYLQTLNKIEKQFNILGSLPVIGIYSGIVRFIAGNVQATAGAILAGAGYIGMVFDEKNKRKWKHMTNCGIHQFFHGILNIIRGYGETVLAGTAYGSFALLIYQLTSCEQFNPRFKYERYPNYFKCPLSMFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2B7</accession>
    <name>A0A0C1K2B7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hist_deacetyl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76816">
        <property type="protein sequence ID" value="KIC76816"/>
        <property type="gene ID" value="DB41_EI00310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="1">
        <location>
            <begin position="21"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="168" mass="18623" checksum="B93909E763E80FB3" modified="2015-04-01" version="1" fragment="single">MLSTVIVEDFLFAQHLTGPSHPESPFRFKVSRYALQNQGLLKRGGILRPRLAKESELLLCHTPCYLQEVQDNVQQCIYSGLKDGSFQLSTGDVQMCPASEKIARYAVGAVLNAVDSVMLAQARNAFCLVRPPGHHACMDKGMGFCLYNNVAIGARYACQRYGLRKVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2C8</accession>
    <name>A0A0C1K2C8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EH00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76826">
        <property type="protein sequence ID" value="KIC76826"/>
        <property type="gene ID" value="DB41_EH00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6778" checksum="B6D6A3D64208EC4E" modified="2015-04-01" version="1">MKCPRHLKFEQKIEKGFRFLKSPASLFLFLKKPKRREALLMVMALCLLGYSALKYKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2I2</accession>
    <name>A0A0C1K2I2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chlamydia protease-like activity factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cpaF_2</name>
        <name evidence="2" type="ORF">DB41_CP00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383161.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77220">
        <property type="protein sequence ID" value="KIC77220"/>
        <property type="gene ID" value="DB41_CP00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.80"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041126">
        <property type="entry name" value="CPAF_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17816">
        <property type="entry name" value="PDZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSPc" evidence="1">
        <location>
            <begin position="361"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="589" mass="67027" checksum="65F08915FBCF326C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2M3</accession>
    <name>A0A0C1K2M3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">mfd</name>
        <name evidence="11" type="ORF">DB41_CO00290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383128.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77260">
        <property type="protein sequence ID" value="KIC77260"/>
        <property type="gene ID" value="DB41_CO00290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.63"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="594"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="777"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC77260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1098" mass="124394" checksum="D87B8ED94DABF5B0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Q2</accession>
    <name>A0A0C1K2Q2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76986">
        <property type="protein sequence ID" value="KIC76986"/>
        <property type="gene ID" value="DB41_DN00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4651" checksum="2D77AB3CF54496E4" modified="2015-04-01" version="1">MIGKKLIYKHWLYKQLLRSLIAGNKSLFLIAPQVTCSEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K340</accession>
    <name>A0A0C1K340_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DA00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000017">
        <property type="protein sequence ID" value="KIC77116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243756.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77116">
        <property type="protein sequence ID" value="KIC77116"/>
        <property type="gene ID" value="DB41_DA00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.188"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024047">
        <property type="entry name" value="MM3350-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012912">
        <property type="entry name" value="Plasmid_pRiA4b_Orf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07929">
        <property type="entry name" value="PRiA4_ORF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159941">
        <property type="entry name" value="SSF159941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B box-type" evidence="1">
        <location>
            <begin position="157"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="217" mass="23720" checksum="7A2C49C8261D8140" modified="2015-04-01" version="1">MKTKGTCTTCGKTYSPSKGSAHLLGCALKSLQPSQSTSEGYLLRISWAEEPGLYWMFVAIPQNTSLRSLDAFLRTTWLECCGHLSEFTIGRRHYMSHTESGKLSASMNNPIGKILSPGLEFTYVYDMGSSTELDIQVLEKLATCPQKEISILMRNDPPAFLCEACNQAADIICSLCGSKLCSKCSTSHPCAIDEKDTYMLMPLVNSPRAGVCGYTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3C0</accession>
    <name>A0A0C1K3C0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative tRNA/rRNA methyltransferase YsgA</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ysgA</name>
        <name evidence="2" type="ORF">DB41_CK00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383049.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77276">
        <property type="protein sequence ID" value="KIC77276"/>
        <property type="gene ID" value="DB41_CK00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="106"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="251" mass="27428" checksum="6E9C5BAA058C8F85" modified="2015-04-01" version="1">MKELSSPQHPLIKHLVKLRQNHDYRWHHQTLVLEGIKLIAEASSLLTFKTILASSAHLLPKNVKAEKIILAAPALIQKVSGLQSSEGILAEAPMPKFSNLYGKKYLLALDRINDPGNLGTIIRSAIALGWEGIFLLEGTCDPFNEKALRASRGAVFKIPMRQGAWKDLQEIIKVNNLQGLVADIKGVPFEQVKPSSGVLLVLSNEAQGPSQEAFSIGSPITVPMSGEMESLNVSVAAGLLLYSLRQKRELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3C2</accession>
    <name>A0A0C1K3C2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CCA-adding enzyme</fullName>
            <ecNumber evidence="7">2.7.7.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cca</name>
        <name evidence="7" type="ORF">DB41_CK00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383055.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77281">
        <property type="protein sequence ID" value="KIC77281"/>
        <property type="gene ID" value="DB41_CK00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.23"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052928">
        <property type="term" value="F:CTP:3'-cytidine-tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CTP:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol" evidence="5">
        <location>
            <begin position="21"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="6">
        <location>
            <begin position="168"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="411" mass="47403" checksum="E54630C17E6212D3" modified="2015-04-01" version="1">MYIKKLATDIVKKLNQAGYKAYFAGGWVRDYLMNQPSADIDIATDAPPEVILKLFPHTLLVGLAFGVVIVILEGYQFEVSTFRKDLEYVNGRKPKSIELSNEEEDVKRRDFTINSMFYDPLEEKIYDYVEGRRDLELGLIRTVGDPFERFSEDRLRMIRAIRFSARFNFRLDEATQQAIQEKANTLFPAVAIERVWKEFVKMAGYPHFANALMEMHRLGLLPVIFPSLAHLHLKDLSQYLSPFSKFPTYTPTILYILELFPSFDTQQLQNLCSYLRLSTEETKLATFVQTGKQLLSLAPGLSDPEWVHFYAHSYSQVCLEIFAARLSEDSEEAFYQEHEQNQERLKPHIKRAIKKQPLVTASMLKSLGVLPGKSMGLLLQEAEKNAILHNLQAPEESIKMLQQSKHWPNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3D5</accession>
    <name>A0A0C1K3D5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CJ00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383033.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77301">
        <property type="protein sequence ID" value="KIC77301"/>
        <property type="gene ID" value="DB41_CJ00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022565">
        <property type="entry name" value="DUF2608"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11019">
        <property type="entry name" value="DUF2608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="299" mass="34890" checksum="EFB86B41B33D7975" modified="2015-04-01" version="1">MKNYFILRHLGRIWLALRGNFFLLVVAILFSMPLSAKVVETHRFADILQEVDSHSILFFDIDDTLINTTSMLGNTPWWSYFVSKMATANLSKDEARLEVNKIIQKIMLQVPMRLIDPSAAEIIRQLQQKGILTFALTARCLNPDYMQEADLCAYKHLKSVGIDFSLNRLPKLIDSNSYKCFSQGIIFTDYQDKGPFLKDFLNYHFLRPSKVIFIDDSPRHMRSVESMMETMGIPFYGFRYSQLDHFHKQFDPLLANIQLEAFLQNDRLLSDEEALKIAQAEPDKNPDYFINELIRKWQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5J6</accession>
    <name>A0A0C1K5J6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385943.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74557">
        <property type="protein sequence ID" value="KIC74557"/>
        <property type="gene ID" value="DB41_IJ00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="143" mass="16221" checksum="BEE25C1545785BB5" modified="2015-04-01" version="1">MKSPNFRNQLYNNAVAIISLIVAVIALAVNTWRLEQTERNRNIRQAGFEMLKNLGGLQAVVNTTLYKDTHSKIEAIEGWNYIAMMSDIVILLPSPVPENLKQLAKIWSVHWKNLATNHNGVSQVNHQIDTTREAVMHALNQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6P1</accession>
    <name>A0A0C1K6P1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385724.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74912">
        <property type="protein sequence ID" value="KIC74912"/>
        <property type="gene ID" value="DB41_IB00450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1477"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="2">
        <location>
            <begin position="4"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="128"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="542" mass="62137" checksum="6E7830236554897B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6R6</accession>
    <name>A0A0C1K6R6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="12">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rlmN2</name>
        <name evidence="12" type="synonym">rlmN</name>
        <name evidence="14" type="ORF">DB41_IB00650</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="12"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385752.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74932">
        <property type="protein sequence ID" value="KIC74932"/>
        <property type="gene ID" value="DB41_IB00650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1501"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="97"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="12">
        <location>
            <begin position="161"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="12">
        <location>
            <begin position="216"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="12">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC74932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="355" mass="40740" checksum="A142FCA16D393F98" modified="2015-04-01" version="1">MTNFCDLTYSELVDWLETYEEKKFHARQLFEWVYKKSILDWDLMSNLSKPLREKLKKGLLLPTLQLVKVTPSTDLETYKFLWKLRDGNLVESVLICSGDRRTVCVSSQVGCPANCAFCASGKQGFFRNLRPGEIVEQIVQINHWLKQKEERVCHVVYMGMGEPLKNYEAVMKSIHLIIDEETLNISQRRITVSTVGIVDGIKRLSTENLKVNLVLSLHAPNQNIRKKIIPYARKYPLEDILAAMDEYSMKTKRDITYEYTLIAGINDHPDHAHELAHLLKGKQCTVNLIPYNPIPNVRLQRPDRKAIKEFRSVLFGCKIVNTCRYTKGDDIAAACGQLAMQQQNLPKPALAMMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6W1</accession>
    <name>A0A0C1K6W1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB01050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385852.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74972">
        <property type="protein sequence ID" value="KIC74972"/>
        <property type="gene ID" value="DB41_IB01050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="15471" checksum="C4B5EF592E7E7004" modified="2015-04-01" version="1">MKMFNFIYRILRRFRYPVSLPEDIAHALGVEFSYGLTFEEFVAQLQCPQLRSTRLKKYMPRQQAEEAFKSALRIDRFSQKSLFSYYFNEGWMEFILQFDEQGCLRRVYLQHKYIPEEMGLEILLSAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K806</accession>
    <name>A0A0C1K806_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">pepA</name>
        <name evidence="11" type="ORF">DB41_HS00050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75307">
        <property type="protein sequence ID" value="KIC75307"/>
        <property type="gene ID" value="DB41_HS00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1331"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M17_N" evidence="10">
        <location>
            <begin position="18"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="178"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="483" mass="53139" checksum="7AB29A5728C37360" modified="2015-04-01" version="1">MRFFSSSNEDSKKFELLVLPFWQGKKQAEKAAQIDRYASHFAPLMMQDFSAKEGEILVVYDTSTKEGKRLALIGLGAKEKIDTEKLRRIYAKLTHLCHQKNIKNICLFCPQVDTLAKDALLTGIAEGILLANYNFDELKQVTKAEHSVLLQQVTFINLSKQELAIAQRCGKIAEGVYMARDLVNRNADEVTPQYLSSFAKALESKLPHVKATILNKKQIEKEKLELLLAVNRGSTSDPAMIILSYQGHPLSKEHTVLIGKGITYDTGGLNLKPVGSMETMKADMAGGAAVLGALYAAASLGLEVNLTVVVPATENSIDSNSFKPGDVYKSCKGLTIEVNNPDAEGRLVLADAITYAIKYLKPTRLIDVATLTGGIDVALGPEACGVFSNNDDLANALMRSGSKTFERVWRLPLYEEYHTYLKSDIADMKNSSGRSASSITAAMFLQEFVEKLLGLIWILQARHFSVRKNATIQSMLQGLGCDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K8Y8</accession>
    <name>A0A0C1K8Y8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_HJ00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385295.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000120.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75602">
        <property type="protein sequence ID" value="KIC75602"/>
        <property type="gene ID" value="DB41_HJ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="5">
        <location>
            <begin position="138"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="852"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="894"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="936"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="978"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1104"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1146"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1314"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1525"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1567"/>
            <end position="1600"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1692"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1819"/>
            <end position="1852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1918" mass="218689" checksum="4C53263169DE0A25" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9W9</accession>
    <name>A0A0C1K9W9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GW00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75942">
        <property type="protein sequence ID" value="KIC75942"/>
        <property type="gene ID" value="DB41_GW00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="17638" checksum="1E3C5DE851BDDE2C" modified="2015-04-01" version="1" fragment="single">MQITPLLGPSPCIFYQKPEIEAKSTNSFVSDSPITEESRSAPPLSSFSSSILSINKSTREERLLTQRLTAYLGREKDLLGETIAHLYAESSLYTPEEKNKLAKLVSYLKLPWFMIKEEERKQLIEQGIKDCLDPRLQPFHTTLAYIADTLASSLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAJ4</accession>
    <name>A0A0C1KAJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative iron-sulfur cluster insertion protein ErpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">erpA</name>
        <name evidence="2" type="ORF">DB41_GN00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243902.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76112">
        <property type="protein sequence ID" value="KIC76112"/>
        <property type="gene ID" value="DB41_GN00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023883">
        <property type="entry name" value="CHP03980_redox-disulphide"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038062">
        <property type="entry name" value="ScdA-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140683">
        <property type="entry name" value="SSF140683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03980">
        <property type="entry name" value="prismane_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="87"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="193" mass="21360" checksum="2BACA0F7251AEC45" modified="2015-04-01" version="1">MTSTQNQENTIIHRQMTIEQILSLFPFKAQKLAQEITRAGLHCVGCHAATWETLEAGMLGHGMNEDQINTLVERLNNLLQEEADLSTITITERAAKKYLEILAEEGKPGWGIRFEEKMAGCSGFEYVLDFSEKAAEDDETFVSHAIEIHVKKAIVPRLLGSEIDYVDGLQGAGFKISNPNARSSCGCGSSHNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBA2</accession>
    <name>A0A0C1KBA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein LemA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lemA</name>
        <name evidence="7" type="ORF">DB41_GD00100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384575.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000089.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76432">
        <property type="protein sequence ID" value="KIC76432"/>
        <property type="gene ID" value="DB41_GD00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.872"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="199" mass="22102" checksum="EB79202F91F83D16" modified="2015-04-01" version="1">MLITIGVIIAILAVIALSLIGIYNRLIETRNQVRNAWSQIDVQLQRRYDLIPNLVETVKGYMGYEKSTLEAVIEARSQASAIREQIKKSGLPSHQAMKELMSTEASLKAGLGNIYALAENYPQLKASDTMHNLQEELSTTENKVAFARQAYNDQVLAYNNIQQKFPAALIATSLGHQPAELYEAESEESKKAVKVSFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBB6</accession>
    <name>A0A0C1KBB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GC00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76452">
        <property type="protein sequence ID" value="KIC76452"/>
        <property type="gene ID" value="DB41_GC00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6701" checksum="158674C0498CB875" modified="2015-04-01" version="1">MEYTKENSIGSANKRTFSHDTSVKNRLDRLSNVEKIYAVEKELFDRLLNASSTTHKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBC2</accession>
    <name>A0A0C1KBC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GC00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
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            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76457">
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        <property type="gene ID" value="DB41_GC00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002152453" evidence="1">
        <location>
            <begin position="22"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="228" mass="25681" checksum="1C2F155A049BED84" modified="2015-04-01" version="1">MIRIVYAFILAVHLKASMVCADQPSSSVNHHPSAISTAQASGSLKAPLISFKKPLNPISTSEGFPFTLPGIVSLKDNQWVGSDNLYNLKPNIRITLELVKGENKNFDINEEEVKGHIQEKLARIGISSTTLHEANQPFLPLFHVLVLVDSIDQFYTASCSCRLFEPVILKRVSLEKGIIYQAITWEKQELITSPKKDFSDLLTKTLNGLTEDFVNRFLYFQKLKYKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
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    <name>A0A0C1KBY2_9BACT</name>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
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    </gene>
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        <name type="scientific">Neochlamydia sp. TUME1</name>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KIC76607.1"/>
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    </dbReference>
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        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
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            <begin position="135"/>
            <end position="190"/>
        </location>
    </feature>
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        <location>
            <begin position="246"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="472"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="684" mass="79621" checksum="4C1F57ACE2069E5C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDF5</accession>
    <name>A0A0C1KDF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
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        <lineage>
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            <taxon>Parachlamydiaceae</taxon>
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            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
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                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000027">
        <property type="protein sequence ID" value="KIC77037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_JRXI01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77037">
        <property type="protein sequence ID" value="KIC77037"/>
        <property type="gene ID" value="DB41_DK00020"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
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        <property type="project" value="InterPro"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09386">
        <property type="entry name" value="ParD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="9439" checksum="F5B185F24DD43626" modified="2015-04-01" version="1">MPAKGHMSRMTIDVPEEDHKRLKALAAVLGKSMREIIIGWIHEHLYSTNTPNAETLEAIKQIERSENLVESDNIDDLFKKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-12-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDQ4</accession>
    <name>A0A0C1KDQ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tlcA</name>
        <name evidence="10" type="ORF">DB41_DB00090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383351.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77102">
        <property type="protein sequence ID" value="KIC77102"/>
        <property type="gene ID" value="DB41_DB00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.200"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187">
        <property type="entry name" value="PTHR31187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00769">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="532" mass="59830" checksum="1529FA92B158EE15" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE00</accession>
    <name>A0A0C1KE00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CS00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77202">
        <property type="protein sequence ID" value="KIC77202"/>
        <property type="gene ID" value="DB41_CS00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8135" checksum="F443B6C97283C8E0" modified="2015-04-01" version="1">MASRMACIKNSINMFSLECLHGFLPFSHKTEEIRLVSFYFFITPTLHRIFKHPAPPSVKLALILLRFGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9M3</accession>
    <name>A0A0C1H9M3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386886.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71568">
        <property type="protein sequence ID" value="KIC71568"/>
        <property type="gene ID" value="DB41_AV00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="228" mass="24586" checksum="11530798AA1ED175" modified="2015-04-01" version="1">MSISGSGTGAPGGIPEFSLLNDQNAAIHALRLSMGIANNLDSISFTEIDKQALWKYDTSPSKPTLHPLEHMRVEVTPPRADDTWKQVLAEITERLPSNVRAAYEQSLQAPIEERNPSLIALGKLLEGAAKVLNGIKNSANALDSQNPIAAAGSPLDIRRQMNLELAEKALQGILKDSFPTFEAIKNSLASLGPNDPFFDELMGAANQLGMAYSTLAHIHNKKAAEDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAB6</accession>
    <name>A0A0C1HAB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IQ00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74299">
        <property type="protein sequence ID" value="KIC74299"/>
        <property type="gene ID" value="DB41_IQ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4576" checksum="937B767C6624CE10" modified="2015-04-01" version="1">MSCSLCNHMLNKKLAFKEKATLEKGKFLFGLCRCSFYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAR8</accession>
    <name>A0A0C1HAR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">scpB</name>
        <name evidence="4" type="ORF">DB41_IM00050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000144">
        <property type="protein sequence ID" value="KIC74504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74504">
        <property type="protein sequence ID" value="KIC74504"/>
        <property type="gene ID" value="DB41_IM00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1628"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="242" mass="27560" checksum="E6F4FF523B1C2782" modified="2015-04-01" version="1">MAKEINFFEQQMETTADELIPPLPPSPPEKLTAPKAFSPKKQYVQGSLPGIPVNNQAIEQKATEKTSRTRLKRIIEALLFVSREPLSFNKIREVLDAVEPLKPRQIQDLLQELAEEFILQQRAFRLEEIAQGYILRTCKEYSPYLDLLFRNKRTEKLSPAAAEVLAIIAYRQPITRPQIDAIRGVDSSGTLQSLLERQLVESVGRLEAPGRPTLYGITPYFLKHFGLRDLKELPGWQPPVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAV4</accession>
    <name>A0A0C1HAV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">tsf</name>
        <name evidence="9" type="ORF">DB41_AE00030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71928">
        <property type="protein sequence ID" value="KIC71928"/>
        <property type="gene ID" value="DB41_AE00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2119"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="8">
        <location>
            <begin position="73"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="82"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="284" mass="31401" checksum="A37B4212F94D97BA" modified="2015-04-01" version="1">MSKMPITATMIKELRERTGVGMGKCKEALEEANGDMELAISNLRKAGIASAVKKEGRTTNEGMIGFFENDKTAAIVEVNSETDFVAKNERFKEFLENIAAEIAKTHPTSLEAFLAQPYSKDTSISIDQYRATVVQTIGENIQIKRLFTAAKSPSKSIGIYSHLGGKVVTMVEIEGSDAEQSLAKDIAMHVAAAHPEFLSPEKVPAELINNEKEIAKSQIKNKPENFIDKIVEGKLNAYYESVCLTKQKFIRDDSKSIAQIVEERAKQSGKPLQLTNFLRWTVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBP8</accession>
    <name>A0A0C1HBP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IC00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000137">
        <property type="protein sequence ID" value="KIC74849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385860.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000137.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74849">
        <property type="protein sequence ID" value="KIC74849"/>
        <property type="gene ID" value="DB41_IC00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="11657" checksum="BFCADF9908D0F78D" modified="2015-04-01" version="1">MGSDDFSAFLFIKGNIEKIEKASQANLYPYQGKTTHRIKELKSKSNEFVLLSMKNNPQIIYHAFISDRSTERLETFQAFRSNHRFWRLSDAAILIWLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBS5</accession>
    <name>A0A0C1HBS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ylyB_2</name>
        <name evidence="5" type="ORF">DB41_KQ00180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386494.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72253">
        <property type="protein sequence ID" value="KIC72253"/>
        <property type="gene ID" value="DB41_KQ00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2025"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="77"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="281" mass="32237" checksum="FDE9F907947DA203" modified="2015-04-01" version="1">MKLTLDQNLSLLDALTLLSPNSSKTTLRSWLKEGRVYVDESVEKVSSKLIKKNQTITVGARPDPYIQDLRVLYEDSHLIVIDKPSGLLSVTSAFEKDNTAHALLKKHFRPRKVYVVHRLDQDTSGVMLFAFSERAYEKLKEIFAEHHIVREYIAIVEGRMEQSQGKWESYLYEDENYFVHSSLNPERGRLAITHYQVIEMSKHYSLVKFTLETGRKNQIRVQCKAAGHPVLGDLKYGSSVTPVRRLCLHAQGLGFNHPINGKPMQFKSSLPQAFKKYFKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBZ6</accession>
    <name>A0A0C1HBZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquinol oxidase polypeptide II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">cyoA</name>
        <name evidence="15" type="ORF">DB41_IB00720</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243978.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74939">
        <property type="protein sequence ID" value="KIC74939"/>
        <property type="gene ID" value="DB41_IB00720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1507"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04212">
        <property type="entry name" value="CuRO_UO_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010514">
        <property type="entry name" value="COX_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034227">
        <property type="entry name" value="CuRO_UO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006333">
        <property type="entry name" value="Cyt_o_ubiquinol_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06481">
        <property type="entry name" value="COX_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000292">
        <property type="entry name" value="Ubi_od_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01433">
        <property type="entry name" value="CyoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="14">
        <location>
            <begin position="24"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="13">
        <location>
            <begin position="127"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC74939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="298" mass="33811" checksum="1D770A5B6A514DD8" modified="2015-04-01" version="1">MSKIYKLAFFIVSLLALFLVVGWFVHNSDIAVLNPKGAIAQRELDLIIQATLLMLIVVIPVFILMIAIACRYRATNSKAKYTPDWDHSHLVEFIWWAIPFVIVLVLSVITWKSSFELDPFKPLQASTKPLTIQAVALQWKWLFIYPEQKIATVNFLQFPKDTPLNFEVTADAPMNSFWIPQLGGQVYAMPGMKAKLHLIAHELGSFRGSSANFSGEGFAGMKFTAEATSSEDFEQWVEKVKQSPKQLSLNEYKKLILPTQNSSADTYTLQKENLFDWIIMSYMMPMDSHSSKSDASLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCC8</accession>
    <name>A0A0C1HCC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KL00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000192">
        <property type="protein sequence ID" value="KIC72433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72433">
        <property type="protein sequence ID" value="KIC72433"/>
        <property type="gene ID" value="DB41_KL00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1972"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="382" mass="43178" checksum="2EE187855D2D46C2" modified="2015-04-01" version="1" fragment="single">TMPSLYKKIAHLHFPRGNTTTQRTLMLAKVYQLNPGLTSTEKVYQVFKQVFTLAKSISPLEFKEKTEEKRYFTLANYSSDLLNVNRLLLWKKLPGGEEYLSREETKYLPLGKKGELFREWIEENYKNIMALDLSKAGLTYLASEIGQLSQLIRLYLNQNQLTSLPAEIGQLSKLQVLKLNQNELIAPLPAAIGQLSNLLLLNLNQNQLTALPAEIGQLSQLRALHLNQNQLTALPAEIGQLSQLQSLELNQNQLTSLPAEIGRLPQLQWLYLNQNQLTSLPAEIGQLSQLQVLYLNQNQLTALPAEIGQLSELHTLELNQNQLTSLPAEIGQLSQLQGLHLNQNQLTALPAEIGQLSQLIEFELAENPLKDIPEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCI1</accession>
    <name>A0A0C1HCI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative sodium-dependent transporter YocR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">yocR</name>
        <name evidence="8" type="ORF">DB41_HW00060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385474.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75094">
        <property type="protein sequence ID" value="KIC75094"/>
        <property type="gene ID" value="DB41_HW00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="452" mass="49588" checksum="1ED1D266DD672503" modified="2015-04-01" version="1">MTRPLWGSRLGFIFAVAGSAVGLANIWRFPYIVGQYGGSAFIIVYLLCLFLIGFPVFMAEMLIGRTAQTSPSGAFRLLGGKLAWSWAGKLTILTGFIVSSFYSAVAGWVLGYLVEAVQGNLSNFTSAAQVADHHRNLMNNPLWGIGFHFCFLLICIGILYLGVRNGIERGNKIMMPLLFLVLLYLVGTGLKMPNAQRGLEFLLKPDWSLITPAAILAALGQSFFTLSIGQGTIVTYGSYLKPDENLVKSSYPVVLMDTLVSLLSAVAVFTIVFSVDLKPDQGSGLIFHTLPWVFSHLPGGHFLASMFFLLVVLAATTSEISAMEPTIAYLMDEWGWKRRQAVLICGLGAFLIGIPSALSSSILADIRWHGMTFLALTDFLANAILIPVGGFLAVILVGWIWGTTHSLNSLKLGSSYFFDNHPWLLHYFRFCFKIMSPILIIFVFLNALGFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDG9</accession>
    <name>A0A0C1HDG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_KC00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386271.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000184.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72813">
        <property type="protein sequence ID" value="KIC72813"/>
        <property type="gene ID" value="DB41_KC00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1852"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="27742" checksum="2D4D446C860FDA01" modified="2015-04-01" version="1">MHNNEHNICLEVQDLQKSYNGRKVVNGLSFYVKKGEIVGLVGPNGAGKTTAFYMTVGLIRPDAGTVSFNQYDVTRSAMHMRARMGMGYLAQEPSVFRYLTVEENIMCILECLPLIKAERKLRLEKLLQELHLEPLAKKKAIALSGGERRRLEITRALVTDPTLLMLDEPFANIDPLSVHEVKQMISHLAQKNISILITDHNAREIFSIVDRSYLVSEGKVILSGTVDTLVNDQQARRTYLGEDFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEA5</accession>
    <name>A0A0C1HEA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JT00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000176">
        <property type="protein sequence ID" value="KIC73068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73068">
        <property type="protein sequence ID" value="KIC73068"/>
        <property type="gene ID" value="DB41_JT00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="159" mass="19112" checksum="D68488F6DC3FD8DE" modified="2015-04-01" version="1">MKNSLDVFQKNCEKWSCTNPQKALLLPYIDCKDLTFCITKQEEQNLKFQHRGETHFFHCQQGALDEAKEWFKMTRLAEVPLIYVYGVGLGYYYQAAQDWLQEDPSRRLVFLEDNLAVIHRLFETHLGFQLVHDPQVQLHFFEDLEKSKELFHILYWNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGU0</accession>
    <name>A0A0C1HGU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FQ00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243851.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000078.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76544">
        <property type="protein sequence ID" value="KIC76544"/>
        <property type="gene ID" value="DB41_FQ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="104" mass="11546" checksum="BA37455294A103B0" modified="2015-04-01" version="1">MSVGFDRSPVSRFLAEIKPNDWQSLSAGKGAKGERYYHWYRLEINSASPEGWHVGFCLRRNVKDSRDVAYYIACCPNNVTSQDMAKAAGSPLDDRGCVAGAQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGU7</accession>
    <name>A0A0C1HGU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FQ00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76549">
        <property type="protein sequence ID" value="KIC76549"/>
        <property type="gene ID" value="DB41_FQ00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10726" checksum="54BEDE10279C18DD" modified="2015-04-01" version="1" fragment="single">MISNDVESGVGPAWYFVNRTDSQAAELVRNAAPPHVFSRIMVATVDHPFFGKDELIRARKITFERTDKDVAWEAIRAFFLHVFKRTNKIQALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH40</accession>
    <name>A0A0C1HH40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76599">
        <property type="protein sequence ID" value="KIC76599"/>
        <property type="gene ID" value="DB41_FI00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4877" checksum="7E6B10BA9E5CF4D9" modified="2015-04-01" version="1">MFAYADKIFRNLNLKLTFSFKLSSSHRGECGYDKVANETLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHD7</accession>
    <name>A0A0C1HHD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_EU00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383956.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000059.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76724">
        <property type="protein sequence ID" value="KIC76724"/>
        <property type="gene ID" value="DB41_EU00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="29"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="16648" checksum="845C45F3D0237B22" modified="2015-04-01" version="1">MSFNLFPSIFNRDPLFRFPKNLMRELEQFYGEERDQGLTIYEDKNNNIVVEAAMPGLNPEEIEINLNKGVLWIKGEKKEEEGDRDKKFYRRSMRSFSYSVALPEQVNDREEPQASYKDGVLQISFQKAKSSEAKRISVKSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIJ0</accession>
    <name>A0A0C1HIJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative arabinose 5-phosphate isomerase</fullName>
            <ecNumber evidence="7">5.3.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">setH3</name>
        <name evidence="7" type="ORF">DB41_DF00080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SIS family. GutQ/KpsF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.13" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77079">
        <property type="protein sequence ID" value="KIC77079"/>
        <property type="gene ID" value="DB41_DF00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.233"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019146">
        <property type="term" value="F:arabinose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004692">
        <property type="entry name" value="KdsD_KpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="6">
        <location>
            <begin position="44"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="213"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="281"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="3">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="3">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="3">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="335" mass="36965" checksum="5B60D20EF483E292" modified="2015-04-01" version="1">MHSSTHGSFSLKRNHHLLEELLQKENSYLNYFFEKIDLSAADIIVQALKDCEGVVVFSGVGKSGLVAEKIAMTMTSTGSRALFISPTNALHGDIGIVSEKDVFVFLSKSGESEELLSLIPTLRNRRVKIIGIVSNAKSRLAKASDIYIDLPLQQELCPFDIVPTTSAVIQLIFGDILAVALMRMKNFSLEEYVKNHPAGRIGKRISLKVSDLMVTGSSLPICKPHDKLVNTLVELSNKRCGCVLVTDETEILQGIFTDGDLRRALQSHGADSLQLPMKDLMIQTARWVAPHNLAWDAMRKMEGDQKNAITVLPVLTEHKKLLGLIKLHDIVQSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIN4</accession>
    <name>A0A0C1HIN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DB00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EUO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042242021.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77109">
        <property type="protein sequence ID" value="KIC77109"/>
        <property type="gene ID" value="DB41_DB00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.207"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="2">
        <location>
            <begin position="15"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_17" evidence="2">
        <location>
            <begin position="83"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="16374" checksum="39B26541B21CE33E" modified="2015-04-01" version="1">MTKPKDNQKFENKLVSITEAAKLNKVTRQAIYVAIKLNKLKASKETTRWTIHLDDLEAYRKQKYSRSKSTFNGELLFDNNKGYYSVNQVAKMLSVPAQKIYYATRVGMLKAQRKGAAWVIHAQDMKQYAESALKKKNIRKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ28</accession>
    <name>A0A0C1HJ28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">23S rRNA (Uridine(2479)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.208</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aviRb</name>
        <name evidence="2" type="ORF">DB41_IJ00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.208" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74533">
        <property type="protein sequence ID" value="KIC74533"/>
        <property type="gene ID" value="DB41_IJ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1583"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="43"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="282" mass="31483" checksum="9F1C8E53F51A06B8" modified="2015-04-01" version="1">MELLQGGNMQGKVIALTSLQNSRVKQVIDLRERRVRDKSEQFIIEGYREVLRAYEAGYKIDSLFYCQELFLGENEKPLIQSLSSKGAQLFLCRENIFRKMSYRDRPDGLIAIAAQQRRGLDQLPSLIKKNTHSPLLVVAEAIEKPGNLGTILRSSDAVHLDALIVCDKCTDIYNPNVVRASVGTLFTVPVIESKGHETIHWLKKHNISIVAATPSAKLEYTQADLKQPVAIAVGTEQLGLSEAWMQQANIQVKIPMLGIADSLNVAMATTLLLYEALRQRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ76</accession>
    <name>A0A0C1HJ76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IJ00440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385958.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74573">
        <property type="protein sequence ID" value="KIC74573"/>
        <property type="gene ID" value="DB41_IJ00440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="754" mass="85715" checksum="28A6417CFEA8DAD8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJE5</accession>
    <name>A0A0C1HJE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_II00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385901.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000142.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74618">
        <property type="protein sequence ID" value="KIC74618"/>
        <property type="gene ID" value="DB41_II00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="745"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="795" mass="92804" checksum="AACAC788EBA911C6" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJH0</accession>
    <name>A0A0C1HJH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IH00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000141">
        <property type="protein sequence ID" value="KIC74643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74643">
        <property type="protein sequence ID" value="KIC74643"/>
        <property type="gene ID" value="DB41_IH00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="7822" checksum="9E9F6A5250165D63" modified="2015-04-01" version="1" fragment="single">MHPISSASIESLPNELLLPILEACVVPPLFSVCKRWHHLLASAVMPSLYKQIGKAHVPQGNVKEQALIVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKG1</accession>
    <name>A0A0C1HKG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB01010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asp23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74968">
        <property type="protein sequence ID" value="KIC74968"/>
        <property type="gene ID" value="DB41_IB01010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005531">
        <property type="entry name" value="Asp23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34297">
        <property type="entry name" value="PTHR34297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03780">
        <property type="entry name" value="Asp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="153" mass="17111" checksum="32A262473DA27B92" modified="2015-04-01" version="1">MPIDVKKVDTKEFELPETLFIRDVDNKVFQGIVLECLNRIEGVTLVESTFIDSIFGRNTTEGARGIIAEQDNKNHSVGIKIEVNVFYGISIPEKAEEIQTLVSEEITHLTGLHVSYVHVVFKNVVTADSKKSLSPVTNPVNLVSTQEDYSDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKI4</accession>
    <name>A0A0C1HKI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">tuf</name>
        <name evidence="10" type="ORF">DB41_HY00090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385543.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74983">
        <property type="protein sequence ID" value="KIC74983"/>
        <property type="gene ID" value="DB41_HY00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1404"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="394" mass="43019" checksum="FF7610B37113A8DB" modified="2015-04-01" version="1">MAKQSFQRNKPHVNVGTIGHVDHGKTTLTAAITKVLAEAGGATFRDYASIDNTPEEKARGITINSTHVEYETDARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGAMPQTREHILLARQMQVPAIVVFLNKVDMLGESDQELLDLVELELHELLESKGYKDVPIVRGSALKALEGDEKYVEAVKHLMRTVDQQIPTPTREIDKPFLMPVEDVFSISGRGTVATGRVERGIVKLNDKLQLVGLGETRDTVATGVEMFNKSMDEARAGENVGLLLRGLEKTDIERGMVLAAPGTCTPHTEFKAPVYVLTKEEGGRKKPFFTGYRPQFYFRTTDVTGTIELPAGVEMVMPGDNVEIIVKLIAPVAMEKGMRFAIREGGHTIGAGTVSEIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HM63</accession>
    <name>A0A0C1HM63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HL00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385317.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75468">
        <property type="protein sequence ID" value="KIC75468"/>
        <property type="gene ID" value="DB41_HL00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1257"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="21"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="81"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="694" mass="78307" checksum="60C282296B12860F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMB6</accession>
    <name>A0A0C1HMB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HK00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000121">
        <property type="protein sequence ID" value="KIC75508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75508">
        <property type="protein sequence ID" value="KIC75508"/>
        <property type="gene ID" value="DB41_HK00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4337" checksum="709CDDD0E4843952" modified="2015-04-01" version="1">MRFKIVESIPPLTMGYGIPINPKTRGEVKSFFISVGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMQ6</accession>
    <name>A0A0C1HMQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">DB41_HJ00030</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385297.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000120.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75603">
        <property type="protein sequence ID" value="KIC75603"/>
        <property type="gene ID" value="DB41_HJ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1246"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="14">
        <location>
            <begin position="34"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="DUF294" evidence="13">
        <location>
            <begin position="250"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="637"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="763"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="805"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="847"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="931"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1015"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1057"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC75603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1185" mass="134656" checksum="82B2117FD2AA0CC9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPY4</accession>
    <name>A0A0C1HPY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GL00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76263">
        <property type="protein sequence ID" value="KIC76263"/>
        <property type="gene ID" value="DB41_GL00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.936"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022028">
        <property type="entry name" value="DUF3604"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12228">
        <property type="entry name" value="DUF3604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="204" mass="22902" checksum="66859E30FA88DE9E" modified="2015-04-01" version="1">MIVVSMHLFFEGDQVQYSPGLTAIIAAEHTRASLAEALYTRSCYATTGERIIVGLYIAGMPMGSEISTAQKHGLLINRHISGFVAGTTRLKSVEIIRNGKVLKSFHPESYSLDFTFDDMTPLETVTVASKDKKPPFVFYYIRVVQEDGHMAWSSPIWVDYVPSAPKRPVSKNAKPTVKLESLKIAEEEEEDNDFDYEDDEDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ26</accession>
    <name>A0A0C1HQ26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76303">
        <property type="protein sequence ID" value="KIC76303"/>
        <property type="gene ID" value="DB41_GK00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="8071" checksum="118392D9E1A80B23" modified="2015-04-01" version="1">MDYFLKYLKRKTRKNSSNLSKPHLLIFYSKKLGFKHIDAFLDRSITKLIKLIYFFLRGIEQRNLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR63</accession>
    <name>A0A0C1HR63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">map_2</name>
        <name evidence="2" type="synonym">map</name>
        <name evidence="5" type="ORF">DB41_FI00180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76608">
        <property type="protein sequence ID" value="KIC76608"/>
        <property type="gene ID" value="DB41_FI00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.691"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="57"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="297" mass="33609" checksum="AFB6EBA02BB2A7FA" modified="2015-04-01" version="1">MIGRNNECWCKSGKKWKKCHFPHLDPKLKETEHSQFLRKEYLKRYNIILKNEQEIKGIRKACHLASYILEETCKIAKAGITTLEINDFAHQLHLDMGAIPAPLHYGHPPFPKSICTSLNEVICHGIPNKIPLREGDILNIDVTCIFEGYYGDCSKMVSIGKISEEKQLVMEVAYECLKRSLAICKPGVEIKEIGNVIEAYARSHHCSVVHQFVGHGVGINFHENPQIPHAYNGSQIPLAPGMIFTIEPMINAGVQEAIIDPEDEWTARTKDGKASAQFEHTLLITHEGHEILTNWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR82</accession>
    <name>A0A0C1HR82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FH00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76628">
        <property type="protein sequence ID" value="KIC76628"/>
        <property type="gene ID" value="DB41_FH00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7529" checksum="CC52E02A39428174" modified="2015-04-01" version="1">MSSPAKIVRSQLNYILASLIVYCKLAFLKIKTSLNHSDQKYKLILKANQMAYQELHNLQKNPMYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRN8</accession>
    <name>A0A0C1HRN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplE</name>
        <name evidence="8" type="ORF">DB41_EI00080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76793">
        <property type="protein sequence ID" value="KIC76793"/>
        <property type="gene ID" value="DB41_EI00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.491"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="7">
        <location>
            <begin position="47"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="148" mass="16405" checksum="F36559CA5377EC58" modified="2015-04-01" version="1">MGIAEPSKDKNAIQACVNELTLLSGQKPVITKAKKAISNFKLREGQPIGIKVTLRGVRMYDFLDRLSNIVSPRIRDFRGFPTKCDGQGNYTLGLDDQQVFPEINLDEVKRTQGMHITFVTSAESDAECVELLRLLGLPFNNLPVSVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRX4</accession>
    <name>A0A0C1HRX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TYR_PHOSPHATASE_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EC00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76868">
        <property type="protein sequence ID" value="KIC76868"/>
        <property type="gene ID" value="DB41_EC00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="1">
        <location>
            <begin position="203"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="314" mass="37006" checksum="852788E4718E4DB8" modified="2015-04-01" version="1">MISLRIFTLIHIACFLLYFTLSANKDRLMPIKEVPLILNMENLENLPKNFRMTTPCYLHKHSNHSLPSLEGLLNLNASASGQFSANGLIQILKTIPYNRIMVIDLREESHGFINGMAVSWYGERNWHNKEKTFEEIKWDENERLQKLLKNQQVHLYDKYTFNPSSSVHVKEVYTENDLICKMGIHHVRLPLTDHVKPGDKQVDSFIELIKTYHLTQENPGYWLHFHCAAGRGRSTALIAMYDMIRNASKVSFKDILKRHAMIGGKDLTAPFEVNDWRYPYHFERLEFMKNFYKYCLDNPNFEQNWSSWISKLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS69</accession>
    <name>A0A0C1HS69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DQ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76938">
        <property type="protein sequence ID" value="KIC76938"/>
        <property type="gene ID" value="DB41_DQ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="5826" checksum="CEDA54ADECD6DC07" modified="2015-04-01" version="1">MNAHRPNSVFIVFKKLENPRKRRNQICSLFAIVTFSILAILCGDDEGVLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSA6</accession>
    <name>A0A0C1HSA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76973">
        <property type="protein sequence ID" value="KIC76973"/>
        <property type="gene ID" value="DB41_DP00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5421" checksum="CDEB70B8BAE13A14" modified="2015-04-01" version="1">MLWYKSKKPLLLVFLNVQGISLFALKVNIDFFFKSSLEEKGKELLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSB3</accession>
    <name>A0A0C1HSB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DO00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000031">
        <property type="protein sequence ID" value="KIC76978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76978">
        <property type="protein sequence ID" value="KIC76978"/>
        <property type="gene ID" value="DB41_DO00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5110" checksum="E2499242EB06462C" modified="2015-04-01" version="1">MSDKMRHEGALGLMLGLTGPHPERTLSLILKVGLLSSQLRYSAGNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSH8</accession>
    <name>A0A0C1HSH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DL00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77023">
        <property type="protein sequence ID" value="KIC77023"/>
        <property type="gene ID" value="DB41_DL00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6482" checksum="CE5DCC05F25BECCC" modified="2015-04-01" version="1">MKNLSNFIGKDVEQKLEQTAISHAGSPLWKTADIGYMAGSQQELRQKKDRLFKKIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT59</accession>
    <name>A0A0C1HT59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">ruvC</name>
        <name evidence="15" type="ORF">DB41_CO00270</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383124.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77258">
        <property type="protein sequence ID" value="KIC77258"/>
        <property type="gene ID" value="DB41_CO00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.61"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC77258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="165" mass="17752" checksum="D237532B8CFA4682" modified="2015-04-01" version="1">MIIIGIDPGTRITGYGIIRVVGNVYQVLDYGCIRPPANYKLTERYLVIFNALEALIHQYSPEALAVETQYVSKNVQSAIKLGMARGIAILAAKKKGIAIFEYSPSKAKLAVVGNGSASKGQVQKMVQLLLKLAQPPKPEDAADALALAICHAHAAQCKSLYEAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HTA2</accession>
    <name>A0A0C1HTA2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CJ00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383035.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77303">
        <property type="protein sequence ID" value="KIC77303"/>
        <property type="gene ID" value="DB41_CJ00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.13"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="12"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="211" mass="22894" checksum="07996D643831088E" modified="2015-04-01" version="1">MIIHTIVSGPFQTNAYVISCPATLQAAIIDPAPGSAPAIIDYLTKNHLLASKILLTHSHWDHIADVAPLKNKYKIPVYVHLLDANNVENPGSDGLPCWIDIEGTKPDHYVKAGEKVPVGNATFEVIETPGHTPGGICFYSQEEQLLFSGDTLFKGTIGNLSFPTARPSLMWGSLSKLARLPPDTRVLPGHGEATTIGAEEWLERAEEFFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JIS1</accession>
    <name>A0A0C1JIS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BP00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000236">
        <property type="protein sequence ID" value="KIC71285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039387023.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000236.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71285">
        <property type="protein sequence ID" value="KIC71285"/>
        <property type="gene ID" value="DB41_BP00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="9873" checksum="A1ABC688121D3E5A" modified="2015-04-01" version="1">MLKEEEVNNVVNRLKNHPNLLESIKELLDITEGIKGIEVADDAEFALIPEVRGLGKKCLEDWAKHQVNEQEAKAQEMKLRQHSKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKX1</accession>
    <name>A0A0C1JKX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AE00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71935">
        <property type="protein sequence ID" value="KIC71935"/>
        <property type="gene ID" value="DB41_AE00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="10362" checksum="BF5C7DA4CCE81CE9" modified="2015-04-01" version="1">MRREEIFVRSRVSLSSREFKKNLSFLPICLTCLICLCAFSHFAFPGKAYKPFKTTASLVKSLKSFHKRKKAATRLFINKCLNDFYFIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL62</accession>
    <name>A0A0C1JL62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AA00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386556.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72025">
        <property type="protein sequence ID" value="KIC72025"/>
        <property type="gene ID" value="DB41_AA00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2078"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="419"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="979" mass="112493" checksum="1F9F7879D8786F98" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLG4</accession>
    <name>A0A0C1JLG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BI00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000229">
        <property type="protein sequence ID" value="KIC71421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71421">
        <property type="protein sequence ID" value="KIC71421"/>
        <property type="gene ID" value="DB41_BI00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2289"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037384">
        <property type="entry name" value="LRRC20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16083:SF2">
        <property type="entry name" value="PTHR16083:SF2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="426" mass="48890" checksum="FDB6F463332B0D38" modified="2015-04-01" version="1">MPSLYRKIARLHFPRKNAITQRTLMLAKVYQLDPGLTSTEKVYQVFKQVFTLVKSIFPLEFKEKTEEKRGLTLANYSSYLLNINRLLLWKKLPGGEEYLRREEIKHLPLEKKGELFRDWIEENCKNITALDLSNAGLTYLPPEIGQLSQLKGLYLNQNQLTSLPVEIGQLSQLEWLYLNQNQLTSLPAEIDQLSQLQELYLNQNQLTNLPAEIGQLSQLQTLYLHQNQLTSLPVEIEQLSQLGKLNLNQNQLTSLPGEIGQLSELQTLLLNQNQLTSLPTEIGQLSKLWRLDLNQNQLTSLPTEIGQLSQLRVLDLNQNQLTSLPTEIGQLSKLRMLHLNQNQLTALPAEIGQLSQLRRFYLSQNQLTSLPAEIGQLSQLQYLYLNQNQIASLPAEIGQMSQLTKLELAENPLKDIVERIRQRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM21</accession>
    <name>A0A0C1JM21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AV00260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386924.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71586">
        <property type="protein sequence ID" value="KIC71586"/>
        <property type="gene ID" value="DB41_AV00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2263"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="705" mass="80258" checksum="9D70B6B396EA801B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMC5</accession>
    <name>A0A0C1JMC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase for insertion sequence element IS702</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KL00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000192">
        <property type="protein sequence ID" value="KIC72430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72430">
        <property type="protein sequence ID" value="KIC72430"/>
        <property type="gene ID" value="DB41_KL00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1968"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027805">
        <property type="entry name" value="Transposase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13613">
        <property type="entry name" value="HTH_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_4" evidence="1">
        <location>
            <begin position="48"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="14870" checksum="88C0398B3BFA4708" modified="2015-04-01" version="1">MKFDKIEKLDDERFRRLTGVKRTTFDKMVQILQEADKAKKIKGGRKYKLSLEDMLLMALEYMREYKTYFHISQSYGVSESSAYKAVKWIEDTLIKHPEETDKIIAGYFTMRDFMSSTYQGNIIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMF4</accession>
    <name>A0A0C1JMF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AM00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71746">
        <property type="protein sequence ID" value="KIC71746"/>
        <property type="gene ID" value="DB41_AM00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="182" mass="21545" checksum="6B55996799DB2648" modified="2015-04-01" version="1">MKYYVPRAFKTSIISNLEKLHYQLIKKTYPTNNKKYKLIIKDIENYLKNKQQFLTFLSNNLLMDVQDPWLLAYNQTKNISLQEASEHLQDLLFSWEELAKYELEEFIPLDLEDLDGYMKKLEEVYQPLLEINSSPALRSAENKRLTELADKISTLKDKIKNQNFSEIPLLCQHIRTIINITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNA0</accession>
    <name>A0A0C1JNA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KD00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386292.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72710">
        <property type="protein sequence ID" value="KIC72710"/>
        <property type="gene ID" value="DB41_KD00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="9330" checksum="FAB44E5664378292" modified="2015-04-01" version="1">MSDPTITSSSTVTSSAAGSPANAATPSASSATNPTAVVEGGSVSNLAELKDQSPEVYSAMMQGIAMNVCSKMAQQQAHLKQVQEEARRASEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNA7</accession>
    <name>A0A0C1JNA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA polymerase sigma-54 factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoN</name>
        <name evidence="11" type="ORF">DB41_KD00200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-54 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386303.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72720">
        <property type="protein sequence ID" value="KIC72720"/>
        <property type="gene ID" value="DB41_KD00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1878"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="10">
        <location>
            <begin position="135"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="9">
        <location>
            <begin position="335"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC72720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="494" mass="57023" checksum="033C656C9892A8D2" modified="2015-04-01" version="1">MSDPISLNLLARQATSLKQTQRLMMSPQMQQAIHLLQMPVLELSATVEQEVQQNPLLDFIEGEEENSNLKKLEEENAEIPEEGEQQPEKELSFNENDFEIMKKLDEEFRDYLYDLPPSSHRTQEEEKLKTFQESSIYAESSLFEYLMQQAKESFDHEEDRAIAEAIIGNFDENGFLQTPLQEIAGLYNFPIGKIKSLLKTIQAFEPYGVGAANMQESLLIQLRCRQKHHTLAYKILEEHYEDLIHNRIPSINKKLACSSEEISKALQKDISRLDLHPGTGHFKHFVQYITPDATIEISNDNLAVRINNDFLPSMRINRRYLQMLEDESLSSDTKEFIRIKLSSAKWLFKNVHQRNDTLLKILELLTNQQKEFFLDDCGKLMPLTMKSIAEQLNLHESTIARAVANKYIDTPRGILPLRSFFTNALQSQKGEDISSNTIKSLLKEIISQEDKKHPLSDATLSKLLTEKGMDCARRTIAKYRAELKLGNAQQRRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNC1</accession>
    <name>A0A0C1JNC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72036">
        <property type="protein sequence ID" value="KIC72036"/>
        <property type="gene ID" value="DB41_AA00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6391" checksum="3E33AEED2A439CB6" modified="2015-04-01" version="1">MPAINLLSDSSDLPTILRKRWEIRGLKPYIGIQFLRAARVFAFLSLAISLAFSICPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPL7</accession>
    <name>A0A0C1JPL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JR00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000174">
        <property type="protein sequence ID" value="KIC73130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73130">
        <property type="protein sequence ID" value="KIC73130"/>
        <property type="gene ID" value="DB41_JR00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1813"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="40"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="17623" checksum="AD1230F7E914EDD2" modified="2015-04-01" version="1">MDTQGFLLTCYVGAADENDRTALIKLLDKCKSLFSTITKVWADMGYQGTVLKQTCQDQYNIDFEIVKRPRRRFRVQEDKIEEFLKTIDLSFKVLPKRWIVERTFAWIGRNRRTSKDYEYLTTTSENWIYLSMIRLMLRRINKLKEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTL8</accession>
    <name>A0A0C1JTL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IY00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244005.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73806">
        <property type="protein sequence ID" value="KIC73806"/>
        <property type="gene ID" value="DB41_IY00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011499">
        <property type="entry name" value="Lipid_A_biosynth_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07578">
        <property type="entry name" value="LAB_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01259">
        <property type="entry name" value="LAB_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="LAB_N" evidence="2">
        <location>
            <begin position="12"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="LAB_N" evidence="2">
        <location>
            <begin position="147"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="234" mass="27217" checksum="1C27CC778CCC4A2D" modified="2015-04-01" version="1">MNEQWREIFYPLGFIASLAFGARFIIQWLRSEISRKSVVTPLFWKLSLLGNLLLLIHSFIQMQFHVGIVQVINAVISWRNLNLMKETSQGMPTVRVIEIMLGFLVLTTCAFYFQHLYLAENKSAWLRLPSHAWSSNSLPIHNSWHIVGFIGLLLFNCRFWIQWWQVEKTHTSQLGASFWWISLLGASFSIVYFIRIYDPVNIIGPALGIVPYIRNLMLLSKNPTYETCGEAYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV05</accession>
    <name>A0A0C1JV05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_IB00330</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74900">
        <property type="protein sequence ID" value="KIC74900"/>
        <property type="gene ID" value="DB41_IB00330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1466"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="389" mass="41790" checksum="4F43419E8CCA1975" modified="2015-04-01" version="1">MSLKKSSSVMAAGLALFSMFFGAGDLIWPLILGGNAGDKNFFAMLGLLVTGVSLPLLGLIAMMMFRGDYRQFFGQTGKWPGLILVFIIQAILGPIGSIPRLITLSFATLKPYMPGNVTLFTFSILSSLLVLGFTLRKNKVINFLGLVLTPLLLLCLGCILVVGFINPPEAHLVTWAPVEAFNQGLHVGYNTLDLIAAFIFAPLVLSHFMTDQEEASSGEKRHEIFNKMLKASLLAAGLLSAMYIGLTSVASFYTHVLPANHLPEERLSAIAMHLLGPQGAFVACLAVAMACLTTAIPLVSICADYIQNDLLPVDKGPLLPLGITLGISLGIANLGFSGIASMLAPLLNILCPSLIVLSISNIINKLYEIRTRKAPIFITFALSTMNYFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV93</accession>
    <name>A0A0C1JV93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">rplK</name>
        <name evidence="9" type="ORF">DB41_HY00060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4 6">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385540.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74980">
        <property type="protein sequence ID" value="KIC74980"/>
        <property type="gene ID" value="DB41_HY00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1401"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0488">Methylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="8">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="7">
        <location>
            <begin position="71"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="14922" checksum="B72B7D8C92EDD38D" modified="2015-04-01" version="1">MAKKVVKIIKLQIPAGKANPAPPIGPALGSAGVNIMAFCKEYNAKTQAMAGDILPVVITVYADKSFTFITKKPPVAELLKKATGVAKGSAVPNRDKVGKITKAQALKVAEEKIQDMNARDLEAATHIVLGTARSMGLELVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVA7</accession>
    <name>A0A0C1JVA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BZ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000245">
        <property type="protein sequence ID" value="KIC71192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71192">
        <property type="protein sequence ID" value="KIC71192"/>
        <property type="gene ID" value="DB41_BZ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="10674" checksum="AB81CB972EFC8B66" modified="2015-04-01" version="1">MGIRGRARVMEQLKWGWRLKPMAKETEVEDKGEGNDAGSAAKCNTTTEGELDKVGVNNGKAQYCGIFPPKGPRALGICGSQQRNPPLVMMSRHSGSKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVH2</accession>
    <name>A0A0C1JVH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Manganese transport system ATP-binding protein MntB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mntB</name>
        <name evidence="5" type="ORF">DB41_IP00060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386017.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74406">
        <property type="protein sequence ID" value="KIC74406"/>
        <property type="gene ID" value="DB41_IP00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1637"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="262" mass="29356" checksum="D792E291E4B7D1DB" modified="2015-04-01" version="1">MKKPQTQPSVLEAHQLTVNYDKTPVLWDINFKVPPGLLVGILGPNGAGKSTLIKSALGLIKPISGKIEFFGLPLKEARKRIAYIPQRQSVDWDFPITVRDLVLMGCYGRLGLLRWPRKADRMAANRYLEMVGMGAYADRQISQLSGGQQQRVFIARAMLQEADLYFMDEPFAGIDIATEKIIMKILIQLKAQGKSVFIVHHDLNNVENYFDWAILLNMRLVACGPVEKIFKADNLQATYGKSFSLFDEAVKLSQDKIKGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVJ1</accession>
    <name>A0A0C1JVJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74421">
        <property type="protein sequence ID" value="KIC74421"/>
        <property type="gene ID" value="DB41_IP00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5335" checksum="7534DC933F330377" modified="2015-04-01" version="1">MNLLSFYQKARVSGYLLKSILDSSYEEDRNQAEGLSRINLSVLKGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW59</accession>
    <name>A0A0C1JW59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_II00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74616">
        <property type="protein sequence ID" value="KIC74616"/>
        <property type="gene ID" value="DB41_II00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1566"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="80" mass="8984" checksum="D0E26D5E58CE53AB" modified="2015-04-01" version="1">MPAEIGQLSELQELELNQNQLTALPTEIGQLSQLQGLDLSKNQLTALPIEIGQLSQLHTLKLAENPLKDIAEKIRQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWQ2</accession>
    <name>A0A0C1JWQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type III secretion needle formation regulating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sctG</name>
        <name evidence="3" type="ORF">DB41_AS00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71662">
        <property type="protein sequence ID" value="KIC71662"/>
        <property type="gene ID" value="DB41_AS00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="157" mass="17875" checksum="6271ABE91A928EFB" modified="2015-04-01" version="1">MEKKDSSSMTKEMVEDFKEDFSLFIEAGFIAVKQLDEISASRIFQAAQTLNPESTAPQIGLGYIALNKLEVKQATKIFEEVVQKEPENYLAQTFLGISFLLTKPKRKKGEKLIQEAMDKSNDPTVKNLGFLSLQWAQKDLNDLKSHFFNHEKGEVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWS4</accession>
    <name>A0A0C1JWS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74891">
        <property type="protein sequence ID" value="KIC74891"/>
        <property type="gene ID" value="DB41_IB00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="6257" checksum="7BFEEC0205FC34B4" modified="2015-04-01" version="1">MYLIKKFQETDSKAFVCFLNEQFEDNGWKKENEDKLRKRVLSCLQAMKDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWZ8</accession>
    <name>A0A0C1JWZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-related protein DsbJ</fullName>
            <ecNumber evidence="2">5.3.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dsbJ</name>
        <name evidence="2" type="ORF">DB41_IB00940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74961">
        <property type="protein sequence ID" value="KIC74961"/>
        <property type="gene ID" value="DB41_IB00940"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1528"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="335" mass="38031" checksum="D8668575DBD37D0E" modified="2015-04-01" version="1">MVGVTFFITPAKGISTDSLQWMTNYEEAENLSRATFKPLILFFTGSDWCNWCSKLEQESLDTPEFAQAVGDKFIFMRLDFPVNSTLPTPLAVQNKQLQKKYNIRSFPTLIILDGQQQKQIGITGYRAGGGKMYAAHLSKIVADYFDYQKKLEAINKQKYSSAELKKLYAVAQNFGYESDINQIIKVGVNSEDSHFFMIERYRKMTQEGLSGLAEATALKKELQLMDPNNEKMTHYHLALIDFEGYTEAGDKRSADLAVASLVNYIQKFGPKDKEHLWRLQMIISQIYFDRNNLTEALNFAESSFTSAPPTAKIEISTAIKNIKSQMATETAVVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX19</accession>
    <name>A0A0C1JX19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AI00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71802">
        <property type="protein sequence ID" value="KIC71802"/>
        <property type="gene ID" value="DB41_AI00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4433" checksum="149FD68529824FD0" modified="2015-04-01" version="1">MELSNKGNIKLTKPCRILFNFSLPEVAAYLSIISFMTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX62</accession>
    <name>A0A0C1JX62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxB</name>
        <name evidence="6" type="ORF">DB41_HI00040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75650">
        <property type="protein sequence ID" value="KIC75650"/>
        <property type="gene ID" value="DB41_HI00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1238"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="19"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="331" mass="35855" checksum="CAC65D1E6011FC01" modified="2015-04-01" version="1">MIFVYLPIISRIIPMKKAKLVIIGSGPAGYTAAIYAARANLEPILYEGFFSGPSGGQLMTTTEVENFPGFPEGITGPALMEAFRKQALRFGTHILRDDVESVDFSKAPLIINGKEHAYYADAVILATGATANRLDIPGTRDGEFWQKGVTACAVCDGAMPIFRDKKLYVIGGGDSAVEEATFLTKFASKVYLVHRRDKLRASKIMQERALNHPKIEILWDSEIVEVTGENVVQSVTLKNLKTFELTTQEAGGVFFAVGHTPNTKFLQGQIELHDNGYIAVKPGTTQTSHELVFAAGDAQDHVYRQAITAAGTGCMAAIEAERELAARGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXH3</accession>
    <name>A0A0C1JXH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71942">
        <property type="protein sequence ID" value="KIC71942"/>
        <property type="gene ID" value="DB41_AE00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="214" mass="25375" checksum="598D81034C895BA5" modified="2015-04-01" version="1">MIGLFYGCAAYKYPTECYYVEPPLLLEQEERLLYDIYHFQASSHWLYYLIPRHRSQIYWYDVGHWCTWALFGNDDHGLFAEAQLPLFKPCRPTSFLKAFTWMVRNPLHNFCHYVIGNAGCVNDEFTFLKINKKHFSCLHYEPVARTVFAGRYTSFYLGLHGGKPFISLRLSYGPKWKSDFYIGWRERGNFGIKFLPLTKNSLVVWENLPYEDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXU1</accession>
    <name>A0A0C1JXU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72027">
        <property type="protein sequence ID" value="KIC72027"/>
        <property type="gene ID" value="DB41_AA00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2080"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="252" mass="29709" checksum="BCA3248C5B98CA28" modified="2015-04-01" version="1">MERENAYEQTSPLSPHQFYISPTFYHIHRERSFNTGSSKQHNFIYGVHAGYDRIKRCRLYGGLNALYAAGKLQGRSAKGHKLKSCYREGNVEGRVGYTFQMKRGWMPTFVPYLGYGYLCETNKFLKPSPVIHKMRISYDYFTVGFLSLFYPHPSWGIGINFKTRFLFTSKCKISDDPDPHQRDSTISLEHKIQYRFELPLIYRLNGWADKLALSVVPFYEYRHYGGHPDFPFDFAETKMNNYGFDFRCLYMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY36</accession>
    <name>A0A0C1JY36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative DNA-binding protein HU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hup</name>
        <name evidence="2" type="ORF">DB41_GU00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384899.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75965">
        <property type="protein sequence ID" value="KIC75965"/>
        <property type="gene ID" value="DB41_GU00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1034"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="102" mass="11807" checksum="019288DFBFC83859" modified="2015-04-01" version="1">MTKKSTMTKKKLINSISQDKGIHPNDVRHVIQSFLDKMTECLSDGDRLEFRDFGVFEVVERKQKIGRNPKKAEEPIVIPARNAVKFTPGKKMRKLIERPRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-12-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ64</accession>
    <name>A0A0C1JZ64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Geranylgeranyl pyrophosphate synthase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
            <ecNumber evidence="3">2.5.1.1</ecNumber>
            <ecNumber evidence="3">2.5.1.10</ecNumber>
            <ecNumber evidence="3">2.5.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ggpS1</name>
        <name evidence="3" type="ORF">DB41_HH00140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EC" id="2.5.1.1" evidence="3"/>
    <dbReference type="EC" id="2.5.1.10" evidence="3"/>
    <dbReference type="EC" id="2.5.1.29" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75721">
        <property type="protein sequence ID" value="KIC75721"/>
        <property type="gene ID" value="DB41_HH00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1211"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:geranyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="293" mass="32168" checksum="F304942882AB31C0" modified="2015-04-01" version="1">MNMKNVQPNIHGYLHERCKSIEKRLAELTAGKDTAYFNLLEATRYSLLAGGKRIRPLLVVATATALGGSEDLALDPACAVEMIHTYSLIHDDLPCMDNDDFRRGKPSLHKAFTEGHAVLTGDYLLTYAFEIIANGTGLQAHQKIELVNVIAKNAGADGMIGGQIMDIESQQKAIDLHFLQDVHRRKTGALITACIECGVIIANGSPADREILKSFGQKIGLAFQIIDDVLDVTSNKNSDIKNHKTTYATLLGLSEAQELAFEYYQAAMEQLKKLPYDTALLVSLADLLVHRNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K098</accession>
    <name>A0A0C1K098_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YlbG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ylbG_2</name>
        <name evidence="2" type="ORF">DB41_FI00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384156.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76595">
        <property type="protein sequence ID" value="KIC76595"/>
        <property type="gene ID" value="DB41_FI00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.678"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="161"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="302" mass="34866" checksum="B4E065D2EDA17FD1" modified="2015-04-01" version="1">MSNLATHQKGIKNKLGVLKLAETLGNVSHAYKMMGYYSRDSFYRFKELYETGGEAALQDMTRKKLRIKNRVDESIEKAVVDFALQKPAYGQLRVCNELKKQGIFISPGGVRSVWIRYNLETFQKCLKALEAKMAQEEMILTEDQLKAFKKSKEEKEAHGEIETEHLGYLLSKDTYYVGTIKGVGRIYQQTVIDTYSKVAFVKLYDRKNALVAADMLNDQVIPWFEEQDIRVLRILTDSGTEYCGAREHHEYELYLAIEDIDPSCIKARHPQANGICKRFHQTIQNEFYAIAFRKTEKFLKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0K3</accession>
    <name>A0A0C1K0K3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384750.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76281">
        <property type="protein sequence ID" value="KIC76281"/>
        <property type="gene ID" value="DB41_GL00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="120" mass="13822" checksum="73117FDC58264EEF" modified="2015-04-01" version="1">MFFLFPFLLFYSPSLDAIMVANKVEVHLSIEDSAMPQVIVTSVKFNEEDMDLTPKSFMNRRVSKVFKLLPGQYEIQWTTQKAGDAWGGEKETKQHQRMIIIEISDAVVYINIRGEVLATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0N8</accession>
    <name>A0A0C1K0N8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal RNA large subunit methyltransferase K</fullName>
            <ecNumber evidence="5">2.1.1.264</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rlmK</name>
        <name evidence="5" type="ORF">DB41_EU00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.264" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76730">
        <property type="protein sequence ID" value="KIC76730"/>
        <property type="gene ID" value="DB41_EU00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.575"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="147"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="349" mass="40696" checksum="84F295F28CECC44D" modified="2015-04-01" version="1">MIFNSLSNAIFLKNRNEIIVMNEAALYLPSIADGEDKSSSFKNRLRKNYRHIRKWARRTTTDCFRIYDREIRHYPLAIDFYAGRFCVHYFSRTREAPEPSAELKEEIEQALGSLFCVTPDLIYWRTRVRRQKMEQYEKKESSKEYFIGHEYGVKFKINLRDYLDTGLFLDHRETRQIVAAACPGKRVLNLFAYTCAFSVHAARAGATFTKSVDMSNTYTAWGADNFKLNALPLIKNPIIREDCLKFLNQESRTGTKYDIIIIDPPTISRSKKMLQMFDIQIDYVDLLSKAIKLLCKKGVIFFSTNSRNFVFDKSFFSTCSIIDISAKTLPLDFHDPKIHRCWKITPLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Z4</accession>
    <name>A0A0C1K0Z4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipase maturation factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lmf1</name>
        <name evidence="7" type="ORF">DB41_GC00180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76451">
        <property type="protein sequence ID" value="KIC76451"/>
        <property type="gene ID" value="DB41_GC00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009613">
        <property type="entry name" value="LMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463">
        <property type="entry name" value="PTHR14463"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06762">
        <property type="entry name" value="LMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="413" mass="48563" checksum="031F2927F4043157" modified="2015-04-01" version="1">MYKHYLKTPSIFWISTSDRMLKGVALVGIIGASLVLCGFAVSWMLFILCLLYLSYVSPSLYFLSFQWDVLLIEVGFAGFLLSLQSPPLPIAVFLLWVILFRLMFSSGIVKFLLGSQEWRNLSAMQYHYETQPLPNKIAYFFHHQPKWLSQLSTLAVFFFEIILPFFIFTNPDFRVYTFLILVLFQSILILTGNFTFFNGLTIALSFMLLEDNYLPWLQPYLPLPNSPRELFTSLWVSISAISLIVLNFFQLVQLFRSLPSVERVFAIISPFYLVNKYGLFSCMVTRRYEIEVQGSEDGRTWKIYEFKWKPGNLKISPRQAAPYQPRLDWQLWFAALGEVKHNPWFTRFIYRLMENSPEVVKLMKNNPFPDKPPTYMRANLYEYHFTTPQEKKESGNWWKRKYVGIYMPPVSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K106</accession>
    <name>A0A0C1K106_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplD</name>
        <name evidence="7" type="ORF">DB41_EH00140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383792.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76830">
        <property type="protein sequence ID" value="KIC76830"/>
        <property type="gene ID" value="DB41_EH00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.479"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="229" mass="25683" checksum="0D3FAFAA8694EF49" modified="2015-04-01" version="1">MATLKKYNLKGQETGQVIVDERLANAEAHGQMIKDYIVAIRANARQWSANTKTRSEVNHSTKKPHPQKGGGRARQGMLSAPQYKGGGRVFGPRPKFDQHVRINKKERKAAIRCLLAEKIAANRLHVLTESVLNEPKTKVMADFLKVTGLANHRVMFLGEAHYAEVKTEEETKRVSIHHDQHDNFIKSVRNLPKVSFSLATNISGYDVLVAKDIVVTESALIELVEWLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K139</accession>
    <name>A0A0C1K139_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FZ00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000085">
        <property type="protein sequence ID" value="KIC76491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243861.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000085.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76491">
        <property type="protein sequence ID" value="KIC76491"/>
        <property type="gene ID" value="DB41_FZ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.801"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="257" mass="28824" checksum="39E7370FB50BCB5D" modified="2015-04-01" version="1">MSQLQVLHLNQSQLTRLPVEIGQLSQLQVLILSQNQLTSLSAEIGQLSQLQVLILSQNQLTSLPAEIGQLSQLQWLYLSQNQLTTLPTEIEQLPQLTRLFLTQNQLTSLPAEIGQLSQLQELYLTQNQLTSLPAEIGQLSQLQELDSSQNQLTSLPAEIGQLSQLQWLYLSQNQLTSLPAEIGRLSKLQTLHLNQNQLTALPAGIGQLSQLTWLYLNQNQLTSLPAGIGQLFQLTKLELAENPLKDIDEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K156</accession>
    <name>A0A0C1K156_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATP-dependent helicase YwqA</fullName>
            <ecNumber evidence="3">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ywqA</name>
        <name evidence="3" type="ORF">DB41_EC00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243796.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76865">
        <property type="protein sequence ID" value="KIC76865"/>
        <property type="gene ID" value="DB41_EC00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.441"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="450"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="735"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="895" mass="102824" checksum="41D7194AA8EE7D0F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K174</accession>
    <name>A0A0C1K174_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FX00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76511">
        <property type="protein sequence ID" value="KIC76511"/>
        <property type="gene ID" value="DB41_FX00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7513" checksum="98B70F9D954541C1" modified="2015-04-01" version="1">MLGWENNLSWQEEARRIVFHHSIEELKNCAKKSRFSQIRQRINLILLAKSKLPHHLIAKTCGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1S8</accession>
    <name>A0A0C1K1S8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="6">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">nadD</name>
        <name evidence="8" type="ORF">DB41_FH00170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NadD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243837.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76636">
        <property type="protein sequence ID" value="KIC76636"/>
        <property type="gene ID" value="DB41_FH00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.671"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="9"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="211" mass="24255" checksum="24C94E94BD196F19" modified="2015-04-01" version="1">MRIHKHVGIYGGTFDPIHFGHLNTAIEIMEAHQLDEIWFCPALVNPDKLGAEPTLAYHRLKMLEIALQELPYFGIIPYELERPGPSYTIDTLREIIKEEKKEAYPSKFYLIMGEDTAFSFVHWKEAKEILTLATPLICRRYASEQPIIWEGDPEICAALQTGMTSTYVMEISASRIRERVSQGLYIGHLVPAKVIDYIYQNHLYSSRPGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1T9</accession>
    <name>A0A0C1K1T9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux pump membrane transporter BepE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bepE</name>
        <name evidence="5" type="ORF">DB41_FD00050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76646">
        <property type="protein sequence ID" value="KIC76646"/>
        <property type="gene ID" value="DB41_FD00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.645"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="530"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="866" mass="94378" checksum="479758C750839079" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Y8</accession>
    <name>A0A0C1K1Y8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF302 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243818.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76691">
        <property type="protein sequence ID" value="KIC76691"/>
        <property type="gene ID" value="DB41_EY00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005180">
        <property type="entry name" value="DUF302"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035923">
        <property type="entry name" value="TT1751-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03625">
        <property type="entry name" value="DUF302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103247">
        <property type="entry name" value="SSF103247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF302" evidence="1">
        <location>
            <begin position="39"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="139" mass="15536" checksum="24B1BEC0C3BC0F70" modified="2015-04-01" version="1">MSLPPYPFIVYSSAEAPSKVIEKLISIINAKNVELFALINHAEEALKKGLELPYEQLLIFGDPKTGTLLMQENPAIGIELPLKILVWQNDEGLTQIGYKDPTCLAANYGIKENLQILQKMNDTLNTWVKIALQQAKEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K213</accession>
    <name>A0A0C1K213_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA translocase FtsK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsK</name>
        <name evidence="7" type="ORF">DB41_EY00220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243820.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76711">
        <property type="protein sequence ID" value="KIC76711"/>
        <property type="gene ID" value="DB41_EY00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.599"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="477"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="281"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="494"/>
            <end position="501"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="835" mass="92510" checksum="ABAA979392239008" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K288</accession>
    <name>A0A0C1K288_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Presequence protease</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pitRm1</name>
        <name evidence="2" type="ORF">DB41_DB00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383361.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77110">
        <property type="protein sequence ID" value="KIC77110"/>
        <property type="gene ID" value="DB41_DB00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.208"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M16C_associated" evidence="1">
        <location>
            <begin position="473"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="991" mass="112395" checksum="EEFE6560432F5B49" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2E9</accession>
    <name>A0A0C1K2E9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EG00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76841">
        <property type="protein sequence ID" value="KIC76841"/>
        <property type="gene ID" value="DB41_EG00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="137" mass="15523" checksum="83B4C6FF8958FCAB" modified="2015-04-01" version="1">MSFVYPFPATAKSLKPFTDDFGRRVPSTYKQANWKGRLYCCIQLACSPLTVPLKIVKKAGEIAVTAVLLMDMLIKRGEDFLKKKPALKDWKDEREMALALTDCLLALALCPLTIGASRIRYFVGIINPTRAFPKRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2N3</accession>
    <name>A0A0C1K2N3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DP00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76961">
        <property type="protein sequence ID" value="KIC76961"/>
        <property type="gene ID" value="DB41_DP00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="289" mass="33051" checksum="ABDB48D2B13CC9E7" modified="2015-04-01" version="1">MLYDIRSRQRKNQAKKSSTMKKNLNRPSLSSDTPLSWSDALLAHPFTQWASDNGKILLYSFLGLIIFVFILFQFIWRHAVSEADFVRAEKEFSLFTSSKDISDPAAEVEALKDLHAIMAAHPELYPKYEGLIAETLLLRGKNEEASLYATSAIKRTAYENDPFYTSYAQATLLLANEKYEEGLKAALNLRNRMLEQAQAFKDTPEKLQYGTFLYALNLLRIAMLQQQLSLFTDELATWKEWEELTLKSGEGTLPFYLKGQLFLSFNNLLSEGKASLADYIEARKKLITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2N9</accession>
    <name>A0A0C1K2N9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DP00230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383577.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76971">
        <property type="protein sequence ID" value="KIC76971"/>
        <property type="gene ID" value="DB41_DP00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="82" mass="9354" checksum="A190EF8AF62AE499" modified="2015-04-01" version="1">MIAQDSDRPPLSESNSESWSLPSSNFCPVLSNSSLTLKNTLDGTLKNTLEFDRKCRALEGLFVELQDRVHQMEKHLSQVRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2P6</accession>
    <name>A0A0C1K2P6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76981">
        <property type="protein sequence ID" value="KIC76981"/>
        <property type="gene ID" value="DB41_DN00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.292"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="6060" checksum="634CA684F7A61987" modified="2015-04-01" version="1">MKEITLIFPHQLFEKHPALDKTRPVCLAEEFLFLRYKNFTSRNLCFCEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2S7</accession>
    <name>A0A0C1K2S7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/alanine symporter AgcS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">agcS_2</name>
        <name evidence="9" type="ORF">DB41_DN00320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042241957.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77011">
        <property type="protein sequence ID" value="KIC77011"/>
        <property type="gene ID" value="DB41_DN00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.324"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="463" mass="49084" checksum="7B179525EEA7011E" modified="2015-04-01" version="1">MENVDIFLNNFKNAIWSAPLLIFLIGTGAYLTIILKGVQFRYLGYAIKQVFARTRQNSQGDISPFEALMTSLAGAIGTGAIVGVATGLAVGGLGSIFWMWITAFVGMATKYAESILAVKYRIIDDRGEMMGGPMQYIEKGLGWKWMALLFALLGALAAITTGNLVQVNAITEAIQHLKAVDPFWTGIVLAGITGLVIIGGVKSIGHVAGVLVPIMALFYIIGGLIVITFHFDKIPHAFGLIIKTAFTGQGATGGFVGATLMMAIQSGVSRSVFSNEAGLGISSIAAAAAKTDSPGRQGMITMTGALISTVIVCTVTGLVLAVTQVQGAINDSGEVLNGAAMAFAAFESTIPGGSYIVSIGLILFAFSTVLAWAYYGEKCFEYIFGINSVNVYRILFTLIIIPSAVTKMEIAWYLADITNGLMVIPNLISLIGLSAVVVAENERFLALVQKERLALQKTFESKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Z5</accession>
    <name>A0A0C1K2Z5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DG00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000023">
        <property type="protein sequence ID" value="KIC77071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243764.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77071">
        <property type="protein sequence ID" value="KIC77071"/>
        <property type="gene ID" value="DB41_DG00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_5" evidence="1">
        <location>
            <begin position="7"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="211" mass="24530" checksum="7D916AFD2C9CBB16" modified="2015-04-01" version="1" fragment="single">MKLDLLDIYTDYLISQNQQATATGLSNLLDGQISHDKITRFLNNNSGGSKELWQYVKKQVRHLEQNKGGVLIIDDTIEEKPYTDENEIVCWHFSHTQGRCVKGINLLSCLISYGDHTFPIGFEVIKKDMHFCDVKTKKEKRQSSTTKNQHFRALIQQAVTNQVEFEYVLADNWFGAKDNMEFIHYELKKMFIFGIKSNRLIAFSEEERKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K351</accession>
    <name>A0A0C1K351_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CX00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383293.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77136">
        <property type="protein sequence ID" value="KIC77136"/>
        <property type="gene ID" value="DB41_CX00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="203" mass="22508" checksum="75083C095C28F73D" modified="2015-04-01" version="1">MSLINCDYKNFTNNQSVDKNITFLPTRTKDTTTFFWGIAEPLHPPAAQLSSQASSHPSQNAGNEPTPLPPLLPLKPPEDILKQGEEIKSRKLLSNGIKYIGPLKAGLPEGIGKLTYEMINEKTQTLFFTTYSGEFRGGRLNGRGLIVYSNGDKLTGNFQHNLLVGLGKLVRQDGKTFSILQNPDHSYLIIEPLYLNKGCFSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K4I7</accession>
    <name>A0A0C1K4I7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_IR00070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386049.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74237">
        <property type="protein sequence ID" value="KIC74237"/>
        <property type="gene ID" value="DB41_IR00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1667"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="427" mass="45340" checksum="BBB06891218C8F13" modified="2015-04-01" version="1">MKNKVLIKVFASIFLAVGAGLWSGADKALGGVPFVQLYNLIGQLFLNALTLVVVPLVSSSIIVGAARMGSEGALGTLGYKTFSYFILTMVLAVVVGLACVMLIKPGIGQPVEELKSSHPQASRLVELHAQGQSGSFQKIEQLLLKLVPSNILAAASQGQMLGLIFFSLLFGYFTSTIDPYPSQVILGFWNAIFQVMMKITHLVMRALPIGVFGLVAKVVATTGIETFRSVAWFTLTFFIALFIYAGIVLPLLLKFVAKVSPLAHVRAMAPALLTAFSTSSSAATLPLTLECLEKRAHVSNRICSFTVPLGTSLNLTASALFICVTVFFIAQVYSVTWSLGSIATIFLLIIFSSIGMAGIPSACLVGAILVLHTIGLPVDAIGLVLAVERLLDMCRAVVNVFGTSCCAVLVARSEKEKNTLTSLSGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6J9</accession>
    <name>A0A0C1K6J9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385611.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74877">
        <property type="protein sequence ID" value="KIC74877"/>
        <property type="gene ID" value="DB41_IB00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1442"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026360">
        <property type="entry name" value="Xnuc_lig_assoc"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04122">
        <property type="entry name" value="Xnuc_lig_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="334" mass="37871" checksum="6DD82ED72EEA333C" modified="2015-04-01" version="1">MKIPLEVRREGLYCCPGQFYIDAWKPVPLSIITHAHGDHAYRGHQHYITSKDSKDLLLHRLGSHISLQVLSYGEKIKIKDCWVSLHPAGHILGSSQIRIETNNTVTVISGDYKRALDPTCQPFETLECDIFVTESTFGLPIYRWQDSLEIAKEMFEWWEQNKANNHPSIIYSYSLGKAQRILSLLKSFTDQSAYLHGAMMSLTKIYAEKGIEMLPFIACSEQPKGYTFSKDLILAPPSAAGSPWLKRFPHFRAAAASGWMLVRGARKRKGMDQGFVLSDHADWEGLIQTIKQSQAKVVLTTHGSTDVLAKYLREQLHVDARELRGLDVLEEEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7I0</accession>
    <name>A0A0C1K7I0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">V-type ATP synthase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atpD</name>
        <name evidence="5" type="ORF">DB41_HW00290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385504.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75117">
        <property type="protein sequence ID" value="KIC75117"/>
        <property type="gene ID" value="DB41_HW00290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1384"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="215" mass="24429" checksum="C641CD6BBA098FC6" modified="2015-04-01" version="1">MAEFKLTKNELRMQQNKLAQLQKYLPTLQLKKAMLQIEVNEARSEILKLEHHYHSLRLEVKSYAELLSDKSEIDPMGAASILAIHKHYENIAGVEVPYFEGIDFADFHYSLFDTPPWLDGVVLGVRGLAEAQVKIDIAQEKKAALENELREVAIRVNLFEKILIPRALSNIKKIKVFLGDQLLAAVSRAKVAKSKIEGHKKHLLEQRALQAGEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K927</accession>
    <name>A0A0C1K927_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein soc-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">soc-2</name>
        <name evidence="3" type="ORF">DB41_HI00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75647">
        <property type="protein sequence ID" value="KIC75647"/>
        <property type="gene ID" value="DB41_HI00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1235"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="279" mass="31090" checksum="755EB337428CF73C" modified="2015-04-01" version="1">MQLQELYLSNNQLTTLPTEIGQLLQLQELYLSNNQLTTLPTQIEQLSQLQELGLNHNQLTILPAEIGQLSKLQRLGLSNNQLASLPLEIEQLSQLQTLDLSSNKLTSLPVEIRQLSQLKELGLNNNQLTSLPTEIGQLPQLQGLGLNNNQLTTVPAEIGQLSKLQRLGLSNNQITILPAEIGQLSKLQRLGLSNNQLASLPLEIEQLSHLQWFGLDHNQLTFLPVEIGQLLHLEVLDLDHNQLTTLPAEIGLLSQLQGLQLKENPLGSIPDEVRRRFCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9H2</accession>
    <name>A0A0C1K9H2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HC00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000113">
        <property type="protein sequence ID" value="KIC75827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243922.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000113.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75827">
        <property type="protein sequence ID" value="KIC75827"/>
        <property type="gene ID" value="DB41_HC00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="107" mass="12163" checksum="9947CF8592F80DD3" modified="2015-04-01" version="1">MIQKNITNEALKKKFKNQFEMVGYAISLAENMILTGRDPRVKSDTQNRALQILEEIVAGKDHLEPVALENKKQEEKEVTRHYLGEKDAGSSSKGAPERKRARKILVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9V2</accession>
    <name>A0A0C1K9V2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GW00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243914.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000108.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75932">
        <property type="protein sequence ID" value="KIC75932"/>
        <property type="gene ID" value="DB41_GW00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="17639" checksum="B0C8BCDAD1220C08" modified="2015-04-01" version="1">MIPLTIDSLYEYLINKSVDVKHQPETKQIYTLFKVQNEAFPLFIGLLNDEELLQLFAPIPIALESQTISEVARVLHLFNKEIDIPGFGLDERAKIVFYRTILPASDKKVAGEILCNYIHTIPLLIETFFPIIAAVVAGKARFIDVVKQGEAAKIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA90</accession>
    <name>A0A0C1KA90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GP00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384830.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000101.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76037">
        <property type="protein sequence ID" value="KIC76037"/>
        <property type="gene ID" value="DB41_GP00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="122" mass="13992" checksum="AC6E228AC2ADD06F" modified="2015-04-01" version="1">MLDYIVGESALYTPTILKVFKREQGLFATRVPLQIKEVKEFIFEAPYDKTVRIVEGYRAFKTTSCYAGVEQRWVVILSQAAYQRECHTLAKPYLKGNAKEAKAFINLMQQEFSCPNDAEDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAX6</accession>
    <name>A0A0C1KAX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative exoribonuclease II</fullName>
            <ecNumber evidence="2">3.1.13.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rnb</name>
        <name evidence="2" type="ORF">DB41_GL00230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384752.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76282">
        <property type="protein sequence ID" value="KIC76282"/>
        <property type="gene ID" value="DB41_GL00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.958"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040596">
        <property type="entry name" value="RNase_II_C_S1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18614">
        <property type="entry name" value="RNase_II_C_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="1">
        <location>
            <begin position="46"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="486" mass="55216" checksum="ED7C3C67900096BD" modified="2015-04-01" version="1">MNSQVNLLEIARQAMLAKGLSPDFPSKVQAQLNRLPALVLDSSNERSDMTNKLWFSIDNDDSLDLDQLTYAERINDHLIRVYVAIADVDALVKKDTPLDRHALTNTTSVYMPMIVFPMLPEKLSTNLTSLNPNEKRASIVVQMDVEESGRVVDYHLFQSYVFNYAKLAYNSVDAWLETGALPPEPIQRIKELASQIRLQDEVAQRLKKHRQSLGFLTWETYDPQPIIKEGQVVDLQEVKINRARELIENLMVAANTCITLFLQKTKCPIIKRVICHPKHWERIVQIADKHKFPLPLNPDSKALENFLIKMRAEDPLNTRDLFLVIIKLLGRGAYIVQSPADKPNQHFGLTLAPYTHATAPNRRYSDLIVQRLLKARLVNQACPYSLSVLQTMLQTCTEKEICADKAKRSVMKSVLALYLEDAIGKTFDAFLTGKGEKGNWIRLISTAIEGKLINGYQNIEVGDRLKVKLVSVNAEKGFLDFVQEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAZ2</accession>
    <name>A0A0C1KAZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dihydroneopterin aldolase</fullName>
            <ecNumber evidence="2">4.1.2.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">folB</name>
        <name evidence="2" type="ORF">DB41_GK00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76297">
        <property type="protein sequence ID" value="KIC76297"/>
        <property type="gene ID" value="DB41_GK00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006760">
        <property type="term" value="P:folic acid-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="1">
        <location>
            <begin position="5"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="121" mass="13734" checksum="D5DEF07CC31F90D3" modified="2015-04-01" version="1">MLGIVGFKNYRLSCIIGVYPYERKHPQELSIDVCYEIDFALITLSDDLSKAVCYASLAEFCSQVAQEGAYQMLETLAHELVLKLADKFSLHWVKVMIRKEKAISLASCTFVELEYGNRLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCA0</accession>
    <name>A0A0C1KCA0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mgtE</name>
        <name evidence="9" type="ORF">DB41_EU00070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383959.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000059.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76727">
        <property type="protein sequence ID" value="KIC76727"/>
        <property type="gene ID" value="DB41_EU00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.572"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="198"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="458" mass="51317" checksum="460AA32C0A82D382" modified="2015-04-01" version="1">MKVSPLTSLNHLIKDKKDQELQESLKSLSGFEIADLIEKKTMPDRLFVFTLLSPQQAAETFDYLSDKQKKQILRSLSSTQIASMLTAMRSDDRTALLEELPQQVVEDYLKLLPPEQRLETLTLLGYPEDSVGRLITTDYIAVKMNWRIEQVFDYIREYGKDSETIDVIYVVDDAGILIDDLRLKEILFHPKEYKIAQITDQKFLALSVHDAAEEAINIFKEYNRVALPVINDEGILLGIVTIDDILRLASEENTNEVHKIGGSDALDEPYLETPFFELIKKRARWLVILFVGEMFTATAMSFFENQISRAVVLALFLPLIISSGGNAGSQSSTLIIRAMALGEVKLKDWWSIMRGEFLLGASLGLILGVVGFIRVSLWGTLGHVYGEHWFLMAVTIFFSLIGVVLWGSLSGAMLPFVLRRLGFDPATSSAPLVATIVDVVGIVIYFTLAMVILEGSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCB5</accession>
    <name>A0A0C1KCB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mutator family transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_ES00010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transposase mutator family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000057">
        <property type="protein sequence ID" value="KIC76742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76742">
        <property type="protein sequence ID" value="KIC76742"/>
        <property type="gene ID" value="DB41_ES00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001207">
        <property type="entry name" value="Transposase_mutator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33217">
        <property type="entry name" value="PTHR33217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00872">
        <property type="entry name" value="Transposase_mut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0814">Transposable element</keyword>
    <keyword evidence="4 6" id="KW-0815">Transposition</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15209" checksum="5AD9C8532906C24F" modified="2015-04-01" version="1" fragment="single">MISDISECKIIAEILEGLIKGGTDNFAPVIEKLLNELMKIERKKCIWAESYERTEERKGYSNGFKDKTLSTRSGLLKLKIPQVRGLKFYPSCLEKGCRSERALKLAIAEMYVQGVSTRRIKQITEELCGFDISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCZ5</accession>
    <name>A0A0C1KCZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DS00080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383616.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76927">
        <property type="protein sequence ID" value="KIC76927"/>
        <property type="gene ID" value="DB41_DS00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="3">
        <location>
            <begin position="246"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="399" mass="45475" checksum="2CD366EC70853246" modified="2015-04-01" version="1">MIIKYIDKEKSYTQYDNQSFDSLEYTVTRPDGKKYSLESGEQTKFTPFHRILIGLKSLALTFFSLGLGMIYSQIREGWKEFFTGKRSIAVYKSDDLQPQSQAHMTSEKADTLFYKFSQEGKSNLDKEIGKPDANPLGETLASEVKTNPKEKVSEPKAQHKASLAASDRVEEDLYYSDDEDIYYEIDLESNENEIDYDELDQKEEDRDLKRLPISSNDPSSKPKRSIKDRCLERLKGDLAAINKEYGTAIDDGDCFFDAFAQALNKKLNGNLTLTDLRRKVSEYVNTLPSQNNWIKNSLEEEYGNIDSYESYVKGVKYNSSEAEKHGGYPIWGKSEIEGVILCHLYQVNLKVYEVGDGGDGMDGLWVAELEYPLSTPYDTTVELALYPGHFLPVYDKKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDJ7</accession>
    <name>A0A0C1KDJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DF00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383401.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77077">
        <property type="protein sequence ID" value="KIC77077"/>
        <property type="gene ID" value="DB41_DF00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021725">
        <property type="entry name" value="Cdd1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11731">
        <property type="entry name" value="Cdd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="96" mass="11133" checksum="E7790FB1998B928E" modified="2015-04-01" version="1">MSIKKKNLKDLKNVGKATLRDLNILDIHLVEDLIHHDATQLFEQLERLTGKRHDPCMWDVFAAIIHEAKTGEPTSWWAWTAQRKALQKTGKLIHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE11</accession>
    <name>A0A0C1KE11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Octanoyltransferase LipM</fullName>
            <ecNumber evidence="2">2.3.1.181</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lipM</name>
        <name evidence="2" type="ORF">DB41_CR00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383192.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77212">
        <property type="protein sequence ID" value="KIC77212"/>
        <property type="gene ID" value="DB41_CR00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="29"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="237" mass="26841" checksum="8F7AC395E01E3A4A" modified="2015-04-01" version="1">MKWIILQDAVDTAQNNMDKDLKLLQNIGCTVNPILRFYGWQGPCATYGYFINPLHFLDVEGVQKHRLQLGRRPTGGGIVFHLTDLAFSVIIPAKHPRYSLNTLDNYAWVNQQVAEAVKAFKNEIVTAFLKIEPLSNSELCRHFCMAKPTIYDVMVEGKKIGGAAQRRTREGFLHQGTLSIAFPDESLLKAVLKTGTEVLEAMKSHSYVLEEGAGTNQLEEIRHQLRHLLVLQFEKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KEA1</accession>
    <name>A0A0C1KEA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative RNA methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rumA1</name>
        <name evidence="5" type="ORF">DB41_CJ00070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383024.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77297">
        <property type="protein sequence ID" value="KIC77297"/>
        <property type="gene ID" value="DB41_CJ00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.7"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="485" mass="55119" checksum="3C3124EF2DCB9163" modified="2015-04-01" version="1">MPYSKQTRFANVKINEFSKRGHGLGRIERSEEEIKEAEIAFAIPGDAVHSMLHGKNKTHWVGGIQRIIEPSKDRIIPKCIHFGSCGGCQWQQMSYDTQLRYKESLAKDIFRSVITPETHLFPIMPSESEWNYRNKMDFTFSRDLNKTKYLGLILDSTKGKVFNLVECHLPNPWFTQAVHAVKSWWEESNLEAYYPIKNTGSLRSLTLREGMKTGDRMVMLTVSGNPDYALQNRHLESFVHALHTAIEPQQSNAKLSIFVRIQQISPGMATNFYEMLLYGPQYIEEELDIQADIEKPAETYKFRISPSSFFQPNIRQIEKVYSLALQLAKVNKEDTIYDLFCGSGVLGICASKNVKQVIGIEISPETAFDARQNAALNNRQNVTIISGAVRYALGQIQDENLFPLPDLVLLNPPRAGLDPLTMKHLLRLNAPKILYISGNPQAHLANIAELSQNGYTVKYIQPYDQFPQTIHVDSLILLEKTPSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H121</accession>
    <name>A0A0C1H121_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BG00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000227">
        <property type="protein sequence ID" value="KIC71434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71434">
        <property type="protein sequence ID" value="KIC71434"/>
        <property type="gene ID" value="DB41_BG00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2287"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="91" mass="10415" checksum="3E1B380FBA7D3838" modified="2015-04-01" version="1" fragment="single">WLYLNQNQLASLPAEIAQLSQLQVLELNQSQLTSLPAEIGRLSQLRVLKLDQNQLTTLPTEIGQLPQLQTLELAENPLKDIDEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2T3</accession>
    <name>A0A0C1H2T3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="14">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">secA_2</name>
        <name evidence="14" type="synonym">secA</name>
        <name evidence="19" type="ORF">DB41_AE00140</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="14">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the SecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="14"/>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386659.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71939">
        <property type="protein sequence ID" value="KIC71939"/>
        <property type="gene ID" value="DB41_AE00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2131"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="12 14 15" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 14 15" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="18">
        <location>
            <begin position="2"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="101"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="546"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="117"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="636"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KIC71939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1031" mass="118073" checksum="340EDB0F37FE2B0E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4N9</accession>
    <name>A0A0C1H4N9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative poly(Beta-D-mannuronate) O-acetylase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">algI</name>
        <name evidence="11" type="ORF">DB41_KK00150</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386394.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72489">
        <property type="protein sequence ID" value="KIC72489"/>
        <property type="gene ID" value="DB41_KK00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1950"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC72489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="485" mass="56139" checksum="A3ADD478ADBABA84" modified="2015-04-01" version="1">MLFNSYLFIFIYLPIVVAIFFVCCYFHLKKGAQLFLLISSLIFYAYWDVRFVPLLCASILFNYIAGNQIYNASTSQVKKLYLLLSLTFNLALLLYFKYLNFFISSANYFLSSEIKLLDIILPLGISFFTFTQIAYLVDVYQARAVPGGWCSYSLFVTVFPHLIAGPVLHHKEMITQFDNPANYQWSSYNFAQGTFLFVIGLAKKVLIADAMYGYVTPVFDQNQTLIPFLQAWIGALAYSIELYFDFSGYSDMAVGLGLYFNIQLPLNFNSPYQATSIIDFWRRWHISLSNFLRDYLYIPLGGNRYGETRKLANLLLTMLLGGAWHGANWTFVVWGLCHGFFLMINHLWRKLNIKLSPLLGQSFTFFCVVVAFVIFRSPDLHRAWMILKGLFGYNGVILPEKYEYSLAFLKAYGVTFERLHFSNVRLYDLLKILACLLATLLLPNSMWWKERFIKYPILSGLSLSAIFIICLIDLDAVTEFLYYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H630</accession>
    <name>A0A0C1H630_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JZ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000182">
        <property type="protein sequence ID" value="KIC72929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72929">
        <property type="protein sequence ID" value="KIC72929"/>
        <property type="gene ID" value="DB41_JZ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1840"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="412" mass="46955" checksum="AB32B81909FFD5D5" modified="2015-04-01" version="1">MDKDTNSFDLLFLIFFILFLKDENAKKVIPTQGNKMHPISSTSIESLPNELLLPILEACAVPSLFSVCKRWHHLLASEAMPSLYKQIGKVHVPQGNVKEQALIVDRIYKLEEKLSEAEKVNAIFRRIFTLAKSFSALVFKVQIEEKRNLTLANYSSYLLNINRLLLWEKLHGGKKYLSREEIKHLPLEKKGELFRNWIEENCGNITALDLSRVGLTCLPPEICQLSQLQTLYLNQNQLTALPAEIGQLSELRGLYLSQNQLTSLPAEICQLSQLQTLDLSENQLTVLPAEIGQLSELQYLYLNQSQLTALPTEIGQLSQLQVLYLNQNQLTSLPAEIGQLSKLTRLYLHQNQLTSLPAEIGRLSKLTRLYLNQNQLASLPAEIGQLFDLQTLELAENPLKDIDEKIRQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA61</accession>
    <name>A0A0C1HA61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AP00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000212">
        <property type="protein sequence ID" value="KIC71723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244113.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000212.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71723">
        <property type="protein sequence ID" value="KIC71723"/>
        <property type="gene ID" value="DB41_AP00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2185"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="539" mass="60875" checksum="669E6EC2397AE14A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBR5</accession>
    <name>A0A0C1HBR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosylmethionine/S-adenosylhomocysteine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KQ00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386479.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72243">
        <property type="protein sequence ID" value="KIC72243"/>
        <property type="gene ID" value="DB41_KQ00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="151"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="309" mass="35117" checksum="544CCACF25CA8B87" modified="2015-04-01" version="1">MFFVFVLFALFASVFTVGKVALEYAQPFFLIGSRMLVAGILLLAYEFYRKGAHISMNWHSFGRILRLAFFNIYITNVLEFWGLKYLTSFKTCFIYSLSPFISALFSYFIFTEKMSIKKWIGLMIGFVGILPMLLSETSAEQKAGHFFMFSWAELAVIIAATTSVYGWILLRQLVNENLYSPLLANGMSMLIGGIITLFHSMLVEDWKPVPVNLNNLVPFFICAAWLLLVSNLICYNLYGWLMKRFSATFMSFAGFSTSMFSALFGWALLGEELGLAFFISSALNLLGLSLFYQEELKKSSVRVDQQTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBW8</accession>
    <name>A0A0C1HBW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine phosphatase stp</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">stp</name>
        <name evidence="2" type="ORF">DB41_IB00470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385726.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74914">
        <property type="protein sequence ID" value="KIC74914"/>
        <property type="gene ID" value="DB41_IB00470"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1479"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017018">
        <property type="term" value="F:myosin phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="257" mass="28692" checksum="E1BD9A986092579C" modified="2015-04-01" version="1">MFMNLKYYKVSVYGISDKGLVRSNNEDFWTHVHELDFVVLTDGMGGHRAGEVAAREAAKALCEHLQQTLAIAGPSLSIDEAHGLIQLSIEHANHTVYELSKAEKEWRGMGTTLCCLLCHPQGIIYAHVGDSRIYRLHNARLRQLTKDHSLLRELVDLGQVNERSKDKFIYKNIITKAVGTEKSVEPSVHISDVAKNDIYLMCSDGLTDMLSTKEIESVLNSVQNIEVAARILVAKANEKGGHDNITLVIVKIDETRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD82</accession>
    <name>A0A0C1HD82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KD00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72723">
        <property type="protein sequence ID" value="KIC72723"/>
        <property type="gene ID" value="DB41_KD00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4738" checksum="9052EBB3DB5FA113" modified="2015-04-01" version="1">MQIKEVKELIFEVPYDKTVEIVESYRAFESTSCHAGFEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDY6</accession>
    <name>A0A0C1HDY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">recR</name>
        <name evidence="9" type="ORF">DB41_HJ00090</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385305.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000120.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75609">
        <property type="protein sequence ID" value="KIC75609"/>
        <property type="gene ID" value="DB41_HJ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1252"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="80"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="198" mass="21671" checksum="6C1368DC28224163" modified="2015-04-01" version="1">MHYPPHLLKVINVLKRLPGVGSKSAERYAFHMLGWPQEYLDEMASTLKDIHEKLPQCEECGCLKGEYACPFCTEPRQQSKVICIISCAREAFSIETTGEYKGLYHVLGGLLSPLEGIGPDKLTIAALKTRIALLKIEEIVIALDSTLEGDATSLYLKQELAPLGVAISRLAFGLPMGSPLDYVDGGTLARAFSGRSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEJ0</accession>
    <name>A0A0C1HEJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative fructose-bisphosphate aldolase class 1</fullName>
            <ecNumber evidence="1">4.1.2.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fbaB</name>
        <name evidence="1" type="ORF">DB41_GZ00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75854">
        <property type="protein sequence ID" value="KIC75854"/>
        <property type="gene ID" value="DB41_GZ00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1084"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00958">
        <property type="entry name" value="DhnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041720">
        <property type="entry name" value="FbaB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="359" mass="39239" checksum="7708BB7E4A6FEA41" modified="2015-04-01" version="1">MLEIADIERFLGAEADSLLHYQCKKVSKEALHLPGPEWLSKIHGVSDRPVRVLASLQTLFNHGRLGGTGYLSILPVDQGIEHSAGATFAPNPIYFDPQNIMKLALESGCNAVASTLETLGLVARKYAHRLPFIAKINHNELLSYPNRYDQILFGNVKQAWNMGAMAVGATIYFGATESNRQIKEISEAFSQAHELGMATILWCYLRNPAFKVDGIDYHESADLTGQANHLGATIGADIVKQKLPLNNGGYKALNKDKKGSYGKYAEAMYTDLCTDHPIDLCRYQVLNGYSGRVGLINSGGASLGQKNLEEAVRTAVINKRAGGMGLISGRKTFQCPLEEGVKIFHAIQDVYLNKAITIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEJ8</accession>
    <name>A0A0C1HEJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_GZ00280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75864">
        <property type="protein sequence ID" value="KIC75864"/>
        <property type="gene ID" value="DB41_GZ00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NB-ARC" evidence="4">
        <location>
            <begin position="205"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="594"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="651"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="914" mass="105359" checksum="DACA3A190039ED64" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEP5</accession>
    <name>A0A0C1HEP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_JP00010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000172">
        <property type="protein sequence ID" value="KIC73178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73178">
        <property type="protein sequence ID" value="KIC73178"/>
        <property type="gene ID" value="DB41_JP00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="DUF294" evidence="4">
        <location>
            <begin position="193"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="592"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="634"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="676"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC73178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="746" mass="85210" checksum="17858734A491A491" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEX4</accession>
    <name>A0A0C1HEX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">IstB_IS21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GR00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75989">
        <property type="protein sequence ID" value="KIC75989"/>
        <property type="gene ID" value="DB41_GR00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="6213" checksum="9AF1D4FF270EF82A" modified="2015-04-01" version="1" fragment="single">GEWGTVFGDSVVATAILDRLLHHSQVITIRGESYRLREKMRSGLVKRGESTNEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HF60</accession>
    <name>A0A0C1HF60_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_Tnp_ISL3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GO00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000100">
        <property type="protein sequence ID" value="KIC76054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76054">
        <property type="protein sequence ID" value="KIC76054"/>
        <property type="gene ID" value="DB41_GO00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="2">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="68"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="18135" checksum="DA12A736258AC75F" modified="2015-04-01" version="1">MTDLTNKRVIDILKDRKKAALKDYMASCDEEFKEGIKYVAIDLWAPSRAVVEEMLPKAQAVADRFHVMQNLNQALDRFRKRVKQESADQEIWKNTKYILLKNHENLTEQQEDVLDKILNLNLELKVYYKLKESFGSLFNGSSTFLKTIGSDQVVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH49</accession>
    <name>A0A0C1HH49_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">trmB</name>
        <name evidence="2" type="ORF">DB41_FI00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384170.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76609">
        <property type="protein sequence ID" value="KIC76609"/>
        <property type="gene ID" value="DB41_FI00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.692"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="26188" checksum="9359FCA4831C6170" modified="2015-04-01" version="1">MKPADLIPPFPKNDRKVTIHDGVWYLPDRHLAQNHFEFPGWSHPLLFGNEQPVNLEYCSGNGAWIVAQAGAYPHLNWVAIERKFTRVRKIWSKIKNCSLKNLIVVCGEGLMATSNYFPSASIANVFINFPDPWPKLRHAKHRLIQPQFVHELARVMQTDKALTFVTDDISYSQEAIQVFLSASDFKSYYPSPYFSTEEVDYGTSYFEELWRSKGKMIRYHRFIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH64</accession>
    <name>A0A0C1HH64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FH00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76629">
        <property type="protein sequence ID" value="KIC76629"/>
        <property type="gene ID" value="DB41_FH00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="73" mass="8476" checksum="ADB9739E341D5370" modified="2015-04-01" version="1">MFKNVGELQGDVDKWMNEYNNERTHTGKYCFGKTPLQTLLDAKHLAQEKMLDKLQLTEIVPARKLMFVMSSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHS1</accession>
    <name>A0A0C1HHS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IT00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74138">
        <property type="protein sequence ID" value="KIC74138"/>
        <property type="gene ID" value="DB41_IT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4992" checksum="4EE33B051B93D04E" modified="2015-04-01" version="1" fragment="single">FLLGGGLMGQKLWLQICFPKFSFIRQPFPRHPCSFFAYYYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHT5</accession>
    <name>A0A0C1HHT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_DZ00010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76879">
        <property type="protein sequence ID" value="KIC76879"/>
        <property type="gene ID" value="DB41_DZ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF294" evidence="4">
        <location>
            <begin position="228"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="620"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="5">
        <location>
            <begin position="629"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="746"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="830"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="872"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="914"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="998"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1082"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1122" mass="127215" checksum="88A26080B33D2FAD" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHU2</accession>
    <name>A0A0C1HHU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DW00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76889">
        <property type="protein sequence ID" value="KIC76889"/>
        <property type="gene ID" value="DB41_DW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="391" mass="44353" checksum="40252E22CC7556FE" modified="2015-04-01" version="1">MIVFIQGKFLKDGALAKHKAATSPSCHTLANTLAISHLASTSSPPQEVSILGLLDHGQYSLQDKRSRETYDRKEPQELRVLLRRSVENIANIYEASRKLMKPSKSKQYSLLVSEVEEEVAKIKILGKVLTDKDQVVESQQIEDQEKVLKQMYKDMPLGESILLRSDIEMMKGMSRRPAEKIYTTAYGTFENPNVSHLELSHWFSSYITEGAFFGFCCMFREHELGEENDFNRMFTCIDLVKNDEQRKIERKLYNGKPSFWGNIQSSLFSIGRNLLSKDQSSSEVEEKKETQALSLPSTEASVAGFISLPTKPVSNYQIKQQKVLAKLAQDLPAMMEVWNVDSFQILTSEQMLAEGYEYEAAYSGNRILLFHKRVENQGAAIAAIDPLPTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI10</accession>
    <name>A0A0C1HI10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="16">UvrABC system protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">uvrA</name>
        <name evidence="16" type="ORF">DB41_DP00060</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383555.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76954">
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        <property type="gene ID" value="DB41_DP00060"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="uvra"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="608"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="958"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="1567"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="640"/>
            <end position="647"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="998"/>
            <end position="1005"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="1599"/>
            <end position="1606"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KIC76954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1898" mass="211220" checksum="5946335D14774E1E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIQ1</accession>
    <name>A0A0C1HIQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_6</name>
        <name evidence="3" type="ORF">DB41_IO00020</name>
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        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
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            <taxon>Parachlamydiaceae</taxon>
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            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000146">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="DB41_IO00020"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
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        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="515" mass="58160" checksum="0A1D15E1473F8F25" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIV1</accession>
    <name>A0A0C1HIV1_9BACT</name>
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        <submittedName>
            <fullName evidence="3">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CS00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77194">
        <property type="protein sequence ID" value="KIC77194"/>
        <property type="gene ID" value="DB41_CS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
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        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="99" mass="11827" checksum="18E289FD4630BBFE" modified="2015-04-01" version="1">MDHSRTKARHPQTNGICERFHQTIQNEFYAIAFRKKVFKNVEELQEDVDKWMNEYNNERIHTGKYCFGKTPLQTFLDANHLAQEMMLDKLQLTEIVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ48</accession>
    <name>A0A0C1HJ48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385934.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74548">
        <property type="protein sequence ID" value="KIC74548"/>
        <property type="gene ID" value="DB41_IJ00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="8653" checksum="F88A6A33FCA09535" modified="2015-04-01" version="1">MKNKTLTLILGMIAICGSMDAHSEEAVCHKCEKVREYNAAHPENNYYWYDDYLKEKKEESQGARPQKEPTSTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK49</accession>
    <name>A0A0C1HK49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IB00110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385613.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74878">
        <property type="protein sequence ID" value="KIC74878"/>
        <property type="gene ID" value="DB41_IB00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="504"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="694" mass="80087" checksum="6B7F62E0F317C033" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKB0</accession>
    <name>A0A0C1HKB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">thrS</name>
        <name evidence="11" type="ORF">DB41_IB00610</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74928">
        <property type="protein sequence ID" value="KIC74928"/>
        <property type="gene ID" value="DB41_IB00610"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1497"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="205"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC74928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="568" mass="65655" checksum="C3185F6909EC039D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKB6</accession>
    <name>A0A0C1HKB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74933">
        <property type="protein sequence ID" value="KIC74933"/>
        <property type="gene ID" value="DB41_IB00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5367" checksum="D561CCBBB341AF80" modified="2015-04-01" version="1">MLSYLRKITLHFHHLHFSPLPFPFIFYYIAQKFSICTFFLNSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLW7</accession>
    <name>A0A0C1HLW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HM00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000123">
        <property type="protein sequence ID" value="KIC75393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385342.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000123.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75393">
        <property type="protein sequence ID" value="KIC75393"/>
        <property type="gene ID" value="DB41_HM00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="425" mass="47725" checksum="BB8884CCACDC3FE8" modified="2015-04-01" version="1">MSVSNGLPQWQSTYPSREGNKEVKNTSSSPKAIFIGERGKVDQAVHQLASASRAAATEKPKSFQRTSLPTANPLVKRIYKRAIKSTPSFTTRQEVPSKPNFMSSKEHGLYKGKRISSLDSQENKNIDNFAKSQFNSFSFKGIWSGLQKVGLAFKAALITASSPLFSFIKSIKAAVLNFFHRQGLPSDLAKFNSFKIKNDERTLKDISEMIVGRGVDHQLSDLKFDDLSVGVQLPTQFSLDLPRADNFVINGKNMFPRTEKTAEEVKNCAEKIYEVLGREETLVVGRFFHQSCTVGLLHKFIQGMEEFNNTNEKNNRYAYGQAPGGELNIEVQKGIAHFSYKLTYQIMREEDPETVMAYCGMETRISLPLEELNNLTHLDLESLEGQEQEKVKELAPNLQAVVACTKFYATLEEAHETNGISKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HM70</accession>
    <name>A0A0C1HM70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HL00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75473">
        <property type="protein sequence ID" value="KIC75473"/>
        <property type="gene ID" value="DB41_HL00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="6001" checksum="72B73EE04FC35681" modified="2015-04-01" version="1">MHNSMVSTGFYLQRQDKEGNPKVDLMGEIKTHPLGMRFSRSIYSQAFIINLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPC7</accession>
    <name>A0A0C1HPC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GN00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243896.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76093">
        <property type="protein sequence ID" value="KIC76093"/>
        <property type="gene ID" value="DB41_GN00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.964"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="113" mass="13340" checksum="08196D1755947B20" modified="2015-04-01" version="1">MTDRGTDYCGAREHHEYELYMAIADIDHSPTKARHPLNPCGICERCHQAIQNKFYAIAFRKKVFKNVEELQADVDKWMNEYNDERTYIGKYCFGKRPLQTFRGKTSCARKDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ05</accession>
    <name>A0A0C1HQ05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76283">
        <property type="protein sequence ID" value="KIC76283"/>
        <property type="gene ID" value="DB41_GL00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="10127" checksum="3CC05F1779225DD2" modified="2015-04-01" version="1">MSFKYIRKEEKITTRRVIAAPKEKKDKDLVKRRAGSRICFIQNLFLFFSQSQAKKSLSTEMLEAFYIFLNRMKVINLIIKYTSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQB9</accession>
    <name>A0A0C1HQB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GG00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76393">
        <property type="protein sequence ID" value="KIC76393"/>
        <property type="gene ID" value="DB41_GG00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5185" checksum="7A1216A4E04ACDBB" modified="2015-04-01" version="1" fragment="single">GKGVDLEYTIKHRRLRDPIVVIHLFQKWTSKLILRREIGVKANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQP4</accession>
    <name>A0A0C1HQP4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TP_methylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_FX00070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384386.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76498">
        <property type="protein sequence ID" value="KIC76498"/>
        <property type="gene ID" value="DB41_FX00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.787"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="238" mass="26971" checksum="00FFA4FA3BAD31D5" modified="2015-04-01" version="1">MNKPALLLLPNLLGDHRYHEIFLPNSVDKVVSTLDGLICESEKAGRRYLSRFKTKKPLSEMTVAIYNEHTPEEDIDFLLEPIRKGERWGLISDAGLPCVADPGSKLVRRARQSGIALQVFNGPSSILLALIHSGFSGQRFTFHGYLKADEAGRLKDIKRLETLSRTDQATQIFMEAPYRNMHMLQSLLNTLAEDTWLCTAWELTMPEQGVVSEPVHRWKKMPLPNLEKKAAIFLVSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQS8</accession>
    <name>A0A0C1HQS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HicB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FU00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384346.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76528">
        <property type="protein sequence ID" value="KIC76528"/>
        <property type="gene ID" value="DB41_FU00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.772"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008651">
        <property type="entry name" value="Uncharacterised_HicB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05534">
        <property type="entry name" value="HicB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="106" mass="12099" checksum="40007396D077279C" modified="2015-04-01" version="1">MMKYKGYTGHVVYDDEAKIFHGEILGIRDVITFQGKTVDELEQAFKDSVQDYLAFCAERKEEPEKPFSGKFNLRLSPELHAKLSVQAKLNHMSLNSYISTVLKTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQX1</accession>
    <name>A0A0C1HQX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384288.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000075.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76558">
        <property type="protein sequence ID" value="KIC76558"/>
        <property type="gene ID" value="DB41_FN00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="179" mass="20424" checksum="3FF288EE9625567F" modified="2015-04-01" version="1">MEPEYRINGGNLANLPDYKVADLISENIPAETYTSIHVKSLMYRFPLTEEDIKARKVFLEVSRLSTTWQSFRVVLEKMLGVRVDNNVQMDKSLIAGQLLGNYSDDAELRDAGIEEVKRAYAECMNVELIISEDCNFCEINLQQQKFYIMAKKVGNVANFVIKTSLKVGPMVPRVFSLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRG3</accession>
    <name>A0A0C1HRG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76718">
        <property type="protein sequence ID" value="KIC76718"/>
        <property type="gene ID" value="DB41_EY00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="260" mass="30457" checksum="922228FB4FB317F3" modified="2015-04-01" version="1" fragment="single">TRVLHFDETGIRCEKKLSWVHVASSPRATLYTLHAKRGQQAMDEANILPQFKGIAIHDHWFPYFSYKQMRHGLCNAHHWRELTFMHEEKQEEWAKQMKELLIFAKQEVEKHVEQGALPLKVLQHIEQAYTQRITDGLTYHLSLPPLPKGRRGKQKQREGKNLLDRLKEKRESVLRFMYDFAVPFTNNQGEQDIRMVKLKQKISGCFRKPTGGQIFCRIRSYISTARKQGWNVWDALADAIRGSPRLLAIDRQANLQEAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRJ4</accession>
    <name>A0A0C1HRJ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">nusA</name>
        <name evidence="9" type="ORF">DB41_EO00060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383892.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76753">
        <property type="protein sequence ID" value="KIC76753"/>
        <property type="gene ID" value="DB41_EO00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.538"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 7" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="135"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="435" mass="48857" checksum="CF338DFBE166F108" modified="2015-04-01" version="1">MNKDLIAIFEYLEREKGIKREIVISAIEESLRAAARKSISGASNVTVTIHPKTGNIDVYCEKEIVDEVEVPAQEISLEEAREIDPESQVGQFIDVIATPRDFGRIAAQKARQIITQKLRGAERDVIYEEYRHRVNELISGTVKRFVRGANLIIDLGKVEALMPMKHYPKTEKYNLGDKVLALLLEVNDTENGGAEVILSRSHPEFVRQLLIQEVPEINDNIVIIDKIARDPGYRTKLTVRSTDPKVDPVGACVGMRGVRVKNVVRELHNEKIDIIPFSADPIELLQNALSPIEIRKINISEDDQTISIVVDDEDFAAVIGKKGMNARLNSELIGYELEVQRMTDYNRTMALQRTELAESDDPSLNEPLEEIDGLNNLIFQHLIAEGYTTLKSLLIATPEELAKIPGISLDTADKIIEQIRKQRIESLGKKPEANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS17</accession>
    <name>A0A0C1HS17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_DW00100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383687.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76898">
        <property type="protein sequence ID" value="KIC76898"/>
        <property type="gene ID" value="DB41_DW00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="252" mass="28029" checksum="F7A325476047BE94" modified="2015-04-01" version="1">MTENTHFTHKAPIEHVAEKLAEGKFSTVEVHGTEIPGHFSAAADAARETAVVLLLMSCIILSFKLPLVSLTLALIIFSTGWTLWKFGRSAWLGWSRLERLHRLVKQEKWEIDHNREQEKMELKDLYANKGFEGKMLDHIVEVLMADGDRLLRVMVEEELGLKLESHEHPLKQACGAGLGAIAAAAMVLTCQLVAPGFQGLVIGSLGTIAAASALSAYYEQNRMIPAVIWNGGLAILAYAWVYFLHEFFFRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS79</accession>
    <name>A0A0C1HS79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DQ00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76948">
        <property type="protein sequence ID" value="KIC76948"/>
        <property type="gene ID" value="DB41_DQ00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="8963" checksum="B935027A944D522B" modified="2015-04-01" version="1" fragment="single">MVELQQVIFRLKFKQSIRSINRDTGIHRTIIRNLNKVANNSGWLSNDRSIPSENEIHQALVAFDLKKPSKSHGLDPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT17</accession>
    <name>A0A0C1HT17_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydroxymethylbilane synthase</fullName>
            <ecNumber evidence="4">2.5.1.61</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hemC</name>
        <name evidence="9" type="ORF">DB41_CR00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77208">
        <property type="protein sequence ID" value="KIC77208"/>
        <property type="gene ID" value="DB41_CR00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.94"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="7">
        <location>
            <begin position="6"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="8">
        <location>
            <begin position="236"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="437" mass="50030" checksum="5418D476D525A14C" modified="2015-04-01" version="1">MQSLSIKVGARSSALSKAQVKEVYQELCRHHAHILFENTYLETTGDKDRITSLRHMGKTDFFTKEVDLLLLSRQCRLAIHSAKDLPEPLPPGLVISAITHGVDPADVLVLRPGQTIEDLPSRACIATSSLRREERVKELRKDLTFCDLRGTIPERLELLEKGQADGVVVAEAALIRLNLTHLNRIKLPGETVPYQGQLALICREDDTEILELMSCLDSRQPKPQILYLGIDLPEQQEKSLNFIHYPIIRIHPRTFHQTDIREGFQDFLSYTHLIFTSKNAVHIFFKIFSHHKYITHHLHNKEVMCVGSQTAKAFASYDTLSPLISPVETAEGMIDFLQSLPLVNPYLFWPHSALSRSVLADFFIQQKWRFRECILYDTFLNKNLRPLDLTLIDEIHFTSPSTVNAFIEKFGCLPINKRLKAIGPITQRHLMQRLNFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL14</accession>
    <name>A0A0C1JL14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AC00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71980">
        <property type="protein sequence ID" value="KIC71980"/>
        <property type="gene ID" value="DB41_AC00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2101"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10840" checksum="F1AE2C812DB17AAD" modified="2015-04-01" version="1">MQGLYLNQNQLTSLPIEIRQLSQLRWLYLNQNQLTALPAEIGRLPRLTRLYLNQNQLTSLPVEIGQLSQLTKLELTANPLKDIAEEIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM71</accession>
    <name>A0A0C1JM71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AU00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71626">
        <property type="protein sequence ID" value="KIC71626"/>
        <property type="gene ID" value="DB41_AU00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4657" checksum="79C1887561228B3B" modified="2015-04-01" version="1">MNAFHNPGAHPFLFEAFAPTCCQLGAERGHFSLSDRQQFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JT65</accession>
    <name>A0A0C1JT65_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium-transporting ATPase KdpC subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP phosphohydrolase [potassium-transporting] C chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-binding and translocating subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-translocating ATPase C chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 12" type="primary">kdpC</name>
        <name evidence="12" type="ORF">DB41_IQ00030</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the KdpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74300">
        <property type="protein sequence ID" value="KIC74300"/>
        <property type="gene ID" value="DB41_IQ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1654"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00276">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003820">
        <property type="entry name" value="KdpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30042">
        <property type="entry name" value="PTHR30042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02669">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001296">
        <property type="entry name" value="K_ATPase_KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00681">
        <property type="entry name" value="kdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC74300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="195" mass="22176" checksum="111243DB3DFEB602" modified="2015-04-01" version="1">MLRIWTSFKMFLWLTALTGIIYPLFITLIAYLTINNKAEGDFISFNGKWIGAALIGQNFESNRYFWGRPSINNYNPLASGGSNLGPTSEALKKVIEKRKVKIKTTYEEKSDRLIPSELLFASASGLDPHISPQTAYFQVERVIKARGWNENNKEAIFRLIEASIELPRWGFLGAPYINVLKLNLALDAWDKAQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV62</accession>
    <name>A0A0C1JV62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CH00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000253">
        <property type="protein sequence ID" value="KIC71132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71132">
        <property type="protein sequence ID" value="KIC71132"/>
        <property type="gene ID" value="DB41_CH00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5822" checksum="19311CF6D0252FAA" modified="2015-04-01" version="1" fragment="single">NGLIFHPMQVWQHCQISSPEGVQEMIMKDMQATPITVCQIDLSHYFILDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV63</accession>
    <name>A0A0C1JV63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Potassium-transporting ATPase ATP-binding subunit</fullName>
            <ecNumber evidence="12">7.2.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP phosphohydrolase [potassium-transporting] B chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-binding and translocating subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-translocating ATPase B chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">kdpB</name>
        <name evidence="13" type="ORF">DB41_IQ00040</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.6" evidence="12"/>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386037.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000148.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74301">
        <property type="protein sequence ID" value="KIC74301"/>
        <property type="gene ID" value="DB41_IQ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1655"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02078">
        <property type="entry name" value="P-type_ATPase_K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00285">
        <property type="entry name" value="KdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006391">
        <property type="entry name" value="P-type_ATPase_bsu_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43743">
        <property type="entry name" value="PTHR43743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01497">
        <property type="entry name" value="kdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 12" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 12" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="592"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="629"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="671"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="12">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="379"/>
            <end position="386"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="530"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC74301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="698" mass="74616" checksum="21A97ACD2E443F0B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVB4</accession>
    <name>A0A0C1JVB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HIT-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HY00260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385557.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75000">
        <property type="protein sequence ID" value="KIC75000"/>
        <property type="gene ID" value="DB41_HY00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1420"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
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        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="5"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="97"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="112" mass="12346" checksum="B142E8144F0C0CD7" modified="2015-04-01" version="1">MTTNVFAQIIAGKIAVDKVFENERILAFKDIHPVAPVHILIIPKKEIADLQSVQVEDLPLISEIVQVAQLLAKTHHITDGYRLLTNNGALAGQTVFHLHFHLIGGRKLEALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVS6</accession>
    <name>A0A0C1JVS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000144">
        <property type="protein sequence ID" value="KIC74501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74501">
        <property type="protein sequence ID" value="KIC74501"/>
        <property type="gene ID" value="DB41_IM00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7392" checksum="1FD5D03C2A447618" modified="2015-04-01" version="1">MHLIMKIFREKRETQVSRNILSLINLLPGRAEIFKLDRAALTPAKITFSVKKVFCYLLPWFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW68</accession>
    <name>A0A0C1JW68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HQ00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000127">
        <property type="protein sequence ID" value="KIC75340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385411.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000127.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75340">
        <property type="protein sequence ID" value="KIC75340"/>
        <property type="gene ID" value="DB41_HQ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="183" mass="20839" checksum="C5AE81EF42A444D8" modified="2015-04-01" version="1">MNKIQVSICIILMFILSGCVLSLLDSYEEPEQAKFLGDILNNVSKKLQKKYTMRTIGTGIGMPDGVVTMLALSFEKTGPLTQEEGRAIIVGCVEEMIQTVNKNEKIRPYLENYPFTSNNVEIRLFLKTKEGNKIYEPDYGVISEIDGSVNYKYKSSENPKKYSKIEEEKFEEALKMVQNKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWY0</accession>
    <name>A0A0C1JWY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional protein HldE</fullName>
            <ecNumber evidence="2">2.7.1.-</ecNumber>
            <ecNumber evidence="2">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hldE</name>
        <name evidence="2" type="ORF">DB41_IB00790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="2"/>
    <dbReference type="EC" id="2.7.7.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385765.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74946">
        <property type="protein sequence ID" value="KIC74946"/>
        <property type="gene ID" value="DB41_IB00790"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1515"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="15"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="430" mass="47306" checksum="FDBEF08C1BD3173A" modified="2015-04-01" version="1">MVRLTGPFSRLGVCKVLVAGDLMLDTYTIGKALRISPEAPVAIIHVQHEENRPGGAGNVMLNLISLGAEVVAVGRVGNDVYGQALKELLSQEKIDVKGIVTQSSYFTPVKNRIIAENQQVVRVDHEKFMNLEEQLEQQIIDHLPVLFQEVQVVALSDYGKGFLTNTLLNAIIEYAKRLGIPVITDPKGRDFTKYIGTTMIKPNLTEAYSAANLSLATALETVAEKILHQVEAEVLLITRSEAGISIFERKGERQDFPVRVHEVKDVTGAGDTVLAMLAYAIGNKLALAEAAQLANVAAGIAIEHLGCARVTLKQLASRLLKYDGENKVFDEEHIFALQQALKGQKITIINVSGVEGLTSTIFQAIRKIAQQDHLKLLVYIRDEKPSEDFIHILASLQEVEFIILATSSLDNFCQLLKPQELHLIENVYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX44</accession>
    <name>A0A0C1JX44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AF00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71827">
        <property type="protein sequence ID" value="KIC71827"/>
        <property type="gene ID" value="DB41_AF00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="104" mass="12035" checksum="1FDD8B4ADD732065" modified="2015-04-01" version="1" fragment="single">FLPTEIGQLSKLQRLHLSDNLLAIIPIERSQLSQLQSFDLSINQLTIIPKEVEQLSQLKYLYLNDKQLTSVPTDIGQLPEWLTINLEGNFLENISMEVKQRFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXG2</accession>
    <name>A0A0C1JXG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75760">
        <property type="protein sequence ID" value="KIC75760"/>
        <property type="gene ID" value="DB41_HG00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10751" checksum="F0BDE5CD6CA4F3B3" modified="2015-04-01" version="1">MRKFCHKLLKQIKHFHACLKDSAIPMTHHAAEELLRNLAIVRKLGSQSIDGKRWREVLHSCIETLYRQRKSILDFLADAIYAAPNKQTTPSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXJ3</accession>
    <name>A0A0C1JXJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AD00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000204">
        <property type="protein sequence ID" value="KIC71962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386622.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000204.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71962">
        <property type="protein sequence ID" value="KIC71962"/>
        <property type="gene ID" value="DB41_AD00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="101" mass="11791" checksum="5AAAC4774C4DCC2A" modified="2015-04-01" version="1">MDKTLKVLLHDFQMRKVLSREDIAALTKEKRKFMVNRLGQGVYYAAKQLVDKFSNEEESVLAKEMLGLPPELTQFSYDSILILVEVVKKLIQPKKKQIFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY33</accession>
    <name>A0A0C1JY33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KV00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72092">
        <property type="protein sequence ID" value="KIC72092"/>
        <property type="gene ID" value="DB41_KV00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="80" mass="9378" checksum="85654BBA2B27A8F2" modified="2015-04-01" version="1">MKNKLMSLVDKILLRKRGIIESVKNKLKNSCQIEHHRHRSPWNFFVNLISGIVAYAYEACKPCIQFTCTEKPKLMSWLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY43</accession>
    <name>A0A0C1JY43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KV00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244080.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000200.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72097">
        <property type="protein sequence ID" value="KIC72097"/>
        <property type="gene ID" value="DB41_KV00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2072"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="393" mass="44882" checksum="0381B7A5DC537B68" modified="2015-04-01" version="1" fragment="single">KKLSEAAKVNAIFRRIFTLAKYFSPLEFKEKTEEKIGLTLANYSSYLLNINRLLVWKKLPGGKEYLSREEIKHLPLEKKGELLRDWIEENYKNTTALNLSGAGLTYLSPEICQLSKLQVLRLRFNQLTSLPGEIGQLSQLQGLYLYQNQLTNLPTEIGQLSQLHTLDLKENQFTSLPTEIGQLSQLHTLDLKENQLTSLPAEIWQLPKLQALYLNQNQLTALPTEVGQLSQLHTLGLNQNQLTSLPIEIGQLPQLQWLDLSQNQLVSLPTEIGQLSQLQWLYLNQNQLTRLPTEIGQLSQLQWLNLNQNQLTRLPTEIGQLSQLQTLELNQNQLTSLPAEVGQLSQLQGLHLSQNQLTSLPAEIGQLSQLKWLKLAENPLKDISERIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYK7</accession>
    <name>A0A0C1JYK7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KP00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72277">
        <property type="protein sequence ID" value="KIC72277"/>
        <property type="gene ID" value="DB41_KP00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="196"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="240" mass="27531" checksum="902CAAA77BDF1B20" modified="2015-04-01" version="1">MFIEIFFSRLRLRKQPGVIKTIIFLILPLKLCCLGNIEAAPTRYYNDQTAVVLREMRANLDDLRHEVSNHEIEIKTYDEKARTLETIIDSMRQQWIEAGHAQTEAWKDSSKALEMKINSLELLTQGIISDVKQFKTYTNEIATTLSQYKQKLTEFEKIIEFQNQNIDNLHQAIKSVAEALNPTSGLSEKAELPSVRIYKVVPGDTLEKIARKHQTTIQAIKELNGLSHDKIVVGQNLRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ79</accession>
    <name>A0A0C1JZ79_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein DB41_KJ00020</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_KJ00020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386362.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72527">
        <property type="protein sequence ID" value="KIC72527"/>
        <property type="gene ID" value="DB41_KJ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1919"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="241" mass="26434" checksum="8C6B05245C97458E" modified="2015-04-01" version="1">MAGHSKWANIKHRKGKADAKKGKIFSRIAKEIISAVKVGGGPEVKNNPRLRLALEKARAANVPNEIVERNIKKASNADQADYTEMMYELYGHGGVGIIVEVMTDNKNRVASEMRIATNKKGGTIATPGAVSFNFDRKGILQINKGQAPEEELFLKATEAGAEDFDSEDGIYLITTDPTALYSVKEALNQANIACEEASLEMIPKSFIECNEECAKANLALIEWLEALDDVDAVYHNMNFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZG1</accession>
    <name>A0A0C1JZG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative malate transporter YflS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yflS</name>
        <name evidence="7" type="ORF">DB41_GZ00250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384971.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75861">
        <property type="protein sequence ID" value="KIC75861"/>
        <property type="gene ID" value="DB41_GZ00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1090"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42826">
        <property type="entry name" value="PTHR42826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002457">
        <property type="entry name" value="DASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC75861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="480" mass="53022" checksum="C01BF02931D04862" modified="2015-04-01" version="1">MSHPQHSNKVVFKGANFLPLFIACTVGACIGFAPSPVGVEPKAWQLLAIFSALIVGLIGKALPMGAISFLALTTLIVTQTLTLKEALSGFSHPIIWLVVAAFLISKSFIKTKLGMRLAYLLVAFLGKKTLGLGYGVAFTELILAPAIPSNTARAGGIIFPIVRALAVSFGSSPERHSQRLIGSYLTLTAYYCNLITSTMFITAMAANPLIVAVLLNHNIPITWGQWALAASLPGVLSLISVPYLVHKLYPPEIKETPEAKDLAIKNLQQMGPMSKYEWITLVVFFLLIVLWICGESYLSIDSTTVAFLGVCILLLTGVLTWEDIKREQEAWDTLIWFSTLVMIATYLNNFGLIGWMSSHLRAMMANTSWYLAWPMLVLSYFYSHYLFASNTAHVSSMYAAFLTVGLHLHIPPYLIALSLAFSSSLFACLTHYGTGSAPILFGSEYVNLKTWWKMGFIMSFIFLTIWIGIGSLWWKILHLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZH9</accession>
    <name>A0A0C1JZH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">is22-2</name>
        <name evidence="1" type="ORF">DB41_GZ00500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75886">
        <property type="protein sequence ID" value="KIC75886"/>
        <property type="gene ID" value="DB41_GZ00500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="77" mass="8568" checksum="B61F797CC291A4AF" modified="2015-04-01" version="1">MKDTAIPMTHNAAEESLRNLAIAPKLYPGSQSAYGKRWREVLPSCIETLYRQGKSILDFLADAIHAARTEQPIPSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZQ0</accession>
    <name>A0A0C1JZQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GC00270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76460">
        <property type="protein sequence ID" value="KIC76460"/>
        <property type="gene ID" value="DB41_GC00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="67" mass="7868" checksum="FEFC86C50BC46D6B" modified="2015-04-01" version="1">MLIFKECQIDLVTSRCPCCHLQTRPELKENEPFLLGPRLEGFINLLMGQFFLTKFKIKNHDCLDHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZU6</accession>
    <name>A0A0C1JZU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FX00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76495">
        <property type="protein sequence ID" value="KIC76495"/>
        <property type="gene ID" value="DB41_FX00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="191" mass="22294" checksum="39AFCF105572059F" modified="2015-04-01" version="1">MKMMRYVTVVWLPLTLALSLIACKKEPRVESHHTGTQAKETERSKEKIQYSLKADGRLWKLATEDTQEQMKITQYILENEQPENATELFSVTEMTDINITPAEYFSQFITQLQKRYANAKVESKVSVQKINSLLGEWWINGNSPDNTQHEWIHIIKKGNEIAVLRYSTIHTEDLEHARKIWEAILTEAKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZW8</accession>
    <name>A0A0C1JZW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">DB41_FV00010</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000082">
        <property type="protein sequence ID" value="KIC76515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76515">
        <property type="protein sequence ID" value="KIC76515"/>
        <property type="gene ID" value="DB41_FV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF294" evidence="12">
        <location>
            <begin position="262"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="13">
        <location>
            <begin position="641"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="13">
        <location>
            <begin position="740"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="746"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="830"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="872"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="914"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="956"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1040"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="1082"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1171" mass="133200" checksum="7CFACC2D5B618126" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZX8</accession>
    <name>A0A0C1JZX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine/putrescine transport system permease protein PotB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">potB</name>
        <name evidence="6" type="ORF">DB41_FU00100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384341.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76525">
        <property type="protein sequence ID" value="KIC76525"/>
        <property type="gene ID" value="DB41_FU00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.769"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="289" mass="32229" checksum="136F49C436BF7013" modified="2015-04-01" version="1">MKKAKLEELALTIPSFLWLIIFFFIPTLVIFTFAFKPSDPFGGIGEGWTLENIYTLLDASYLLLIWRTVWLSVLTTVFCLACALPVGYQLARASTRTRQLILLLIIVPFWSSFLVRIFAWKALLHPEGFFKNFLVQLHLADPSVSLLYNSGTVLLVMVYTYLPFAVLPIYASASKFNFQLLEAAADLGSTRLYAFVKVFLPSIRKGLGTATLMVFIPAIGAYVIPDLVGGTQSEMIGNKIAQRTFIDRNLPLASGLSALLSIIILLPMSIFTLIQSKAKRLSFEGRAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K094</accession>
    <name>A0A0C1K094_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GM00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000098">
        <property type="protein sequence ID" value="KIC76126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76126">
        <property type="protein sequence ID" value="KIC76126"/>
        <property type="gene ID" value="DB41_GM00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5706" checksum="5AD516F128C54667" modified="2015-04-01" version="1">MNSFHSWEGFWQHKKLETHRSFYNKSKWLRSEKIINLNIIKKTLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0H1</accession>
    <name>A0A0C1K0H1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">dnaX</name>
        <name evidence="7" type="ORF">DB41_FB00070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384032.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76665">
        <property type="protein sequence ID" value="KIC76665"/>
        <property type="gene ID" value="DB41_FB00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.619"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18137">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02397">
        <property type="entry name" value="dnaX_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="38"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="387"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="453"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="403"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="571" mass="62599" checksum="CC9127A578144C0C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0I4</accession>
    <name>A0A0C1K0I4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Demethylmenaquinone methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.163</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ubiE</name>
        <name evidence="4" type="ORF">DB41_GL00070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76266">
        <property type="protein sequence ID" value="KIC76266"/>
        <property type="gene ID" value="DB41_GL00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="154" mass="17141" checksum="758467653D978CE1" modified="2015-04-01" version="1">MLYCAKERANHLNLQPHTLTYLQADAQKIPLAEESIESVTLAYGIRNIPHPQQCFNEIYRVLNTGGTVGILELTQPTQPLIRAGHKLYLKTILPIMGQLVTSNRKAYEYLCNSIRSFISPQELESMLKIAGFKQTSVITLMGGIATILVAKKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Y9</accession>
    <name>A0A0C1K0Y9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EI00300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76815">
        <property type="protein sequence ID" value="KIC76815"/>
        <property type="gene ID" value="DB41_EI00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7353" checksum="BF21FC00C7E6AC23" modified="2015-04-01" version="1">MVLFYDTITARCLLSDKQLRLSHMIYKWLGYLTDDGSLEPIPLFTLLKILKQFILNIRVHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1B4</accession>
    <name>A0A0C1K1B4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DU00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000036">
        <property type="protein sequence ID" value="KIC76905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76905">
        <property type="protein sequence ID" value="KIC76905"/>
        <property type="gene ID" value="DB41_DU00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="466" mass="52895" checksum="1C8CB3A3485CC5AE" modified="2015-04-01" version="1">MSYHLTDHPRKYSLSYQDIGLSLITGLSGIPYASRHWQLSNHAKAKHCLGHRLIACIESIPLAGALAAILERIIVFIQEKLLKNGALTKHKAVTSPSYPTSANTLPVSHLTAINSPPQEISLLRLLDNGQYSLQDSQSREIYNSKEPKELRVLLKQSVENIAKIHEASRKLMKPSRSKQYSLLVSEVEEEVAKIKILGKVLTDKDQVVESKQIEDQEKVLKQMYKDMPLGESILLRSDIERMKSLSRRPVEKTYTTSCGTFENPNVSSLELSRWFSPYIYEGNYECFSCMYREHDIVKEKNFNRMFTCIGLDKKEEQRKIERKLYNGTPSFWKNIQSSLFSIGRTLLSKDQSSDEAEEKKETQALSFPSPKASVAGFISLPTKAVSNYQIKQQKVLAKLAQDLPAMMEVWNVDSFQILTSEQMLAEGYEYEGAYSGDRILLFHKRVENQEVASAAMDPLPTQGKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1C9</accession>
    <name>A0A0C1K1C9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FQ00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76546">
        <property type="protein sequence ID" value="KIC76546"/>
        <property type="gene ID" value="DB41_FQ00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5297" checksum="00B361F55F469028" modified="2015-04-01" version="1">MEPAYRLNGGNLAGLPDYKVADLISQNIPRETYSSINVKSLMYRSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1S3</accession>
    <name>A0A0C1K1S3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">khpA</name>
        <name evidence="2" type="ORF">DB41_FH00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A probable RNA-binding protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76631">
        <property type="protein sequence ID" value="KIC76631"/>
        <property type="gene ID" value="DB41_FH00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="10477" checksum="BFA7228A09524A13" modified="2015-04-01" version="1">MLKMLACKTIKNICRAMKEFVEYIVKNLVDAPNDVNVNCYEGERGMIVEVRVNPHDIGKVVGRKGNTIKALRTISMMICARLGRRVRVEIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1V7</accession>
    <name>A0A0C1K1V7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DL00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77030">
        <property type="protein sequence ID" value="KIC77030"/>
        <property type="gene ID" value="DB41_DL00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6874" checksum="789FAEA169BF57F4" modified="2015-04-01" version="1">MKRGYKHGFILSRHFFLAQLLVLFGDRKRQGVLSISAIYRFLKECKQISLPEKGAIHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2C2</accession>
    <name>A0A0C1K2C2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">fmt</name>
        <name evidence="11" type="ORF">DB41_EH00050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383783.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76821">
        <property type="protein sequence ID" value="KIC76821"/>
        <property type="gene ID" value="DB41_EH00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.472"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037022">
        <property type="entry name" value="Formyl_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="205"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="111"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="315" mass="34696" checksum="F91D4B110FE4BB49" modified="2015-04-01" version="1">MKIVYFGTPQFAADILQHLLNHKIRICAVVTKPDRPKGRSSDLVPTPVKRIAQLQNPPLPVHQPALVSAPEFAEILQAYQADLFVVVAYGEIIKQHVLDMPSKGCINVHASLLPKYRGAAPIQHSIINGENETGITIMYMVRKMDAGDIIKMVKVPIGPNTTYGKLERLLCEAGGKALVEVLDQFEQGSVEHVEQDHSQATFAPKIELEDCEINWSSSAKAIHNLVRGVYPHPGAWCYVNIGGQKKRLKINSTIPLAHQGGPAGTLLPTDNEELIVACGQGALRILELQLEGKKAMLAEELIRGFPKDKKMDFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2D5</accession>
    <name>A0A0C1K2D5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">dnaA2</name>
        <name evidence="9" type="synonym">dnaA</name>
        <name evidence="14" type="ORF">DB41_CV00030</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9 10">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383248.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77165">
        <property type="protein sequence ID" value="KIC77165"/>
        <property type="gene ID" value="DB41_CV00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.130"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="145"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="357"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="153"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC77165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="448" mass="50931" checksum="4EA426BAC6D06A14" modified="2015-04-01" version="1">MLVLETEDIWTQFLECVKAKCSATAFGNWLSPIRVIENAGDKITLEIPNIFVKEYLFSNFHSELCAFLPVNANGEPSIQFKLATPAKKTSSTLLNVPASYTPPVEEQTYEVKLNPNYRFETFIEGPANQFVKSAAIGIAARPGQSYNPLFIHGGVGLGKTHILHSIGHYIRQNNKKLRVQCITTEAFINDLVDNLRNKSVDRMKRFYRSDVDVLLVDDIQFLQNRLNFEEEFCNTFETLINQNKQIVITSDKPPSQLKLSERMIARMEWGLVAHIGVPELETRVAILQHKAQQKGLEIPNAVAFFIAEHIYNNVRQLEGALNRLSAHSRLLNLHITEEFVEKTLREMLQHAPRHKITVDQILKSVAAIFQVRVSDLKGSMRTKEVALPRQVAMYLACKMINESLQMLGAAFNKTHSTLLHACKNIEKKLTADETLRRQISMVERNIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2G5</accession>
    <name>A0A0C1K2G5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CS00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77200">
        <property type="protein sequence ID" value="KIC77200"/>
        <property type="gene ID" value="DB41_CS00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="31"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="10305" checksum="203BE81179F80134" modified="2015-04-01" version="1">MAKKTFANTGYSGEEIKLEAALHGIDLTAIKRSKLKGFHLQAKRWIVERTFAWFGKCRRLSKDYEALPNTSQAFLYLAMIRLMVRRIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2M9</accession>
    <name>A0A0C1K2M9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Pyruvate kinase</fullName>
            <ecNumber evidence="3 11">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pyk</name>
        <name evidence="14" type="ORF">DB41_DP00080</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="3 11"/>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76956">
        <property type="protein sequence ID" value="KIC76956"/>
        <property type="gene ID" value="DB41_DP00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.341"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="12">
        <location>
            <begin position="4"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="13">
        <location>
            <begin position="359"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="589" mass="64234" checksum="266F7415FDFA6698" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2N6</accession>
    <name>A0A0C1K2N6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rsgA</name>
        <name evidence="11" type="ORF">DB41_CK00030</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77275">
        <property type="protein sequence ID" value="KIC77275"/>
        <property type="gene ID" value="DB41_CK00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.17"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031944">
        <property type="entry name" value="RsgA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16745">
        <property type="entry name" value="RsgA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="10">
        <location>
            <begin position="149"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="9">
        <location>
            <begin position="158"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="257"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC77275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="384" mass="43612" checksum="1F896CC71B3B9821" modified="2015-04-01" version="1">MKNSKQDDLPRMPKKWVGCDLEADYFKDDRKNSRRERKLASAKDRSKYKKTDRDKRQKNKELHQNIKLAKEDLLRGRVLSITPQGIMVEHEDAIYACSMRGLLKKEKTQFKNLVTVGDLVLFQRTDAQEGLIAHVEERYSVLSRADNLSRRQEQLIAANIDQVLITVSVVNPPLKPFLVDRYIIAARKGGMEPVIVVNKIDLLDHPTTPATEKELYKDFLHAYKAAQIHVIPVSIVNEQGLDQLKSIMKNKASVFSGQSGVGKSSLINAITGLNFKVGKVVEKTKKGSHTTTTAKLIPLEFGGWCIDTPGIKSFGLWDLNKEEVEQYFPEIEEIGQQCKFPNCSHTHEKECAVLAAVENEKLSPLRFASYQYLLEALSQEHLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2P9</accession>
    <name>A0A0C1K2P9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative transposase for insertion sequence element IS702</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_CK00180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77290">
        <property type="protein sequence ID" value="KIC77290"/>
        <property type="gene ID" value="DB41_CK00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.32"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="4">
        <location>
            <begin position="29"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="197" mass="23438" checksum="6AEA33ED2778A931" modified="2015-04-01" version="1" fragment="single">DTLIKSGEFSLPGKKALLEKDSEYEVVLIDASESHVERPKRRVKEKKIRNRNNKQKHFYSGQKKRHTLKSQVVVDKKSRKVICTAFSNGKKHDYKLFKESKVRWTDNRWGIADSGYTGIKKLQRNSRLPKKSRKRKPLTEEEKKQNRALSSENVVNEHVIGSLKRFKIISDRYRNRRRRFGLRFNLMAMIYNYEIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2T1</accession>
    <name>A0A0C1K2T1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6314 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DM00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000029">
        <property type="protein sequence ID" value="KIC77016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77016">
        <property type="protein sequence ID" value="KIC77016"/>
        <property type="gene ID" value="DB41_DM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045632">
        <property type="entry name" value="DUF6314"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19834">
        <property type="entry name" value="DUF6314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6314" evidence="1">
        <location>
            <begin position="54"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="186" mass="21924" checksum="3A48303F76AE5962" modified="2015-04-01" version="1">MTLLSQICLWTGKAKKSKRSKKIFLMAFIPQVQKHQILLAFWESLKNITKLTFISRTYSNDEKGWNGQGRGEVKVTKKSHTLLIFDEKGTWHNQQGMQFNFYNVFQWGLDLKACKISLEHLRQGANRPIFLLHLVPSNPHLLSSLNSYFCKQDIYSGKVYFEPFSFQLTWRIKGPYKNEQIDYSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2V8</accession>
    <name>A0A0C1K2V8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JC00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000160">
        <property type="protein sequence ID" value="KIC73667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386113.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000160.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73667">
        <property type="protein sequence ID" value="KIC73667"/>
        <property type="gene ID" value="DB41_JC00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1722"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1806" mass="203083" checksum="264CD155740E6311" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K301</accession>
    <name>A0A0C1K301_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein yjdF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yjdF</name>
        <name evidence="2" type="ORF">DB41_DF00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77076">
        <property type="protein sequence ID" value="KIC77076"/>
        <property type="gene ID" value="DB41_DF00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016787">
        <property type="entry name" value="UCP021328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11208">
        <property type="entry name" value="DUF2992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="118" mass="13871" checksum="20941393A293E8B8" modified="2015-04-01" version="1">MGGEPSDPEIHEFVLNHYHELKFGEAKEINIQIQRMNPKRVQREVHREMARMKETTQPSTLAQDYMREGLEKKRKKSISSAEKQARKDNQFALKQEKRSIEGITKALLSLRNNSNYMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K307</accession>
    <name>A0A0C1K307_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CitMHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DB41_DF00100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383408.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77081">
        <property type="protein sequence ID" value="KIC77081"/>
        <property type="gene ID" value="DB41_DF00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.235"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045016">
        <property type="entry name" value="NhaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43269">
        <property type="entry name" value="PTHR43269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="330"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="408"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="12">
        <location>
            <begin position="27"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="429" mass="47254" checksum="12952591A6653BDC" modified="2015-04-01" version="1">MAITLNIYTISMIIVFIIGYGFITIEHVIRINKTTTALLMAIICWILQFANHHDKFSHQQNLDSLAAHVADISQVIFFLIGALSVVELINAHQGFKIILDVIKVKSKVRLLWVLGLITFFLSAVLDNLTTTLVMLSIMQKLLTNREDRWLIGGGIVIAANAGGAWTPIGDVTTTMLWIGGQVTSWAIIKNLFFPSLACFIGSFSIISRCLKGSLVDYKLLNAHKKLEPIGKLIFLAGIAALTFVPIFKTLTGLPPFMGILFGLGLLWLMTDIAYFKEEDREHLRVPHVLTKIDLSGVLFFFGILLCINALESAELLKMLAQWLNQHVGNIEVIATLIGIASAIVDNVPLVAASMGMYSLQQYPQNSSFWQLVAYCAGTGGSLLIIGSAAGVVFMGLEKVDFFWYLKKISFPAFVGYVAGITAYYLLSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K388</accession>
    <name>A0A0C1K388_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CP00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77216">
        <property type="protein sequence ID" value="KIC77216"/>
        <property type="gene ID" value="DB41_CP00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.75"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019238">
        <property type="entry name" value="AbiEi_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09952">
        <property type="entry name" value="AbiEi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="251" mass="29086" checksum="87992C850068006C" modified="2015-04-01" version="1">MNSKEGDDMKGQFLINTHYSCEEGNIYANKSAVVLDWLLRIGIYKEQFTIREVSRSRDISIGLVQRVFEVLVMKGFLQTMGVRTAKRFSIKKPELLLKSWLDHYNITKKCKMWTYRTGCEDKTEVLKALESSDLKHTVALALHAAAEAYGTKNTNLQTLELYLINPSMRPQLESSLQLEPQERGYEILLITPYYKSLLSHGLKDQITTKVRVAPCLLTFLDLYHFPLRGHEQAEFMSARLNELKPFYKKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3A7</accession>
    <name>A0A0C1K3A7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77251">
        <property type="protein sequence ID" value="KIC77251"/>
        <property type="gene ID" value="DB41_CO00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5532" checksum="BE43531448851454" modified="2015-04-01" version="1">MLLSSSLGIHILNKNLLRRESAFLKFIYFLDNAGRVSLNSRISKKPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K527</accession>
    <name>A0A0C1K527_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74402">
        <property type="protein sequence ID" value="KIC74402"/>
        <property type="gene ID" value="DB41_IP00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5780" checksum="1C852338C9CBF24F" modified="2015-04-01" version="1">MCHEHIIDVRNYMKDEGKWLLEIALQEGISNRLKLLWSKAKVVSVKEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K534</accession>
    <name>A0A0C1K534_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative metal-binding lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_IP00070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386019.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74407">
        <property type="protein sequence ID" value="KIC74407"/>
        <property type="gene ID" value="DB41_IP00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1638"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="330" mass="37154" checksum="CB9DA7A893049675" modified="2015-04-01" version="1">MKSWLQMGIWMSVFLMVACTSEDQHRRIEREGFGLKNGKIKALSTIAMIGDIVQQVGGEHVDNLTLMRGDLDPHTYQLVKGDDEKLAYADVVFYNGLGLEHGPSLQRFLESNKKAVGLGNKIIKDYPSLVIYSQGQIDPHIWMDMAIWAKIIPYIVEVLSINDPMHAEVFHANGEKLMQDLLQSDQEIKYELGLIPSEKRYLVTSHDAFNYFARAYLATQEERINGKWVQRVASPEGLAPESQLSTSHIQEIIDYLSKHRIQVIFPESNVSKDSLRKIISAGKEKGLNITIAPCCLYADAMGSAGSSGETYQKMIHHDADWIKKCLKVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6Q2</accession>
    <name>A0A0C1K6Q2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lipopolysaccharide heptosyltransferase I</fullName>
            <ecNumber evidence="3">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">waaC</name>
        <name evidence="3" type="ORF">DB41_IB00550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74922">
        <property type="protein sequence ID" value="KIC74922"/>
        <property type="gene ID" value="DB41_IB00550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1489"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002152413" evidence="2">
        <location>
            <begin position="22"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="265" mass="29805" checksum="B3F2133D6AE2F8C6" modified="2015-04-01" version="1">MTCKVTLSLPLLLFLARSAHKIGFGAKSLHEWPNRWVTHHHFDPPKGLNVRDENVYLAQHYFQCYSPLKEEKLILNLSEEQKGVFDLLWNKIKELPGPKILVCAGSAWRNKRLSYEALESFLYEISSNLKVSLILVWGNAEELAIAQKLQAALLTNVSLLDKVSLAVLQNLMSRIDAVIAMDSLPLHLAGMSGTPSFSVFGASSARKYKPKGSLHEAIQGECPYGRTFERRCPVLRSCPTGLCIRGLSGKYLFQQFAHFYSQLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6V7</accession>
    <name>A0A0C1K6V7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB01000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385796.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74967">
        <property type="protein sequence ID" value="KIC74967"/>
        <property type="gene ID" value="DB41_IB01000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025640">
        <property type="entry name" value="GYF_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14237">
        <property type="entry name" value="GYF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="GYF_2" evidence="2">
        <location>
            <begin position="112"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="165" mass="19409" checksum="366F01E64846D858" modified="2015-04-01" version="1">MLTEIVDAALLNRNLYLKIAGCEEKRMMVSLFLLFFLAAFSAYVAKQRGRDPLVWFMLGILLGIFSLILLFVLKPFEGDHLEQKNKIEENLTPKYGALAEEIGEVSYENKEWFYLDQAHHQQGPIYFRELYTLWLDNKITPLTYVWSEGMADWQRIHELPNFINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7J5</accession>
    <name>A0A0C1K7J5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_HV00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385459.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75137">
        <property type="protein sequence ID" value="KIC75137"/>
        <property type="gene ID" value="DB41_HV00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1352"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="199" mass="22285" checksum="679BC2158759DF29" modified="2015-04-01" version="1">MIEIPLFTMTMILFLIMDPIGNISTFLQMVDELPSKRVRWLVAREMLIALVFMLVFNFLGEFILHILQLDNPTVQMASSIILFLTAIKILFPASNSLRANWPKGEPFVIPLAVPLIAGPSLLATILMLAHLESSQPKMLIAILIAWVVSTFVLLFARQLQRALGYNGLMAAERLTGMLLVMLAVQRCLEGIQEFIALFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9I9</accession>
    <name>A0A0C1K9I9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GZ00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384957.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75847">
        <property type="protein sequence ID" value="KIC75847"/>
        <property type="gene ID" value="DB41_GZ00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1077"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="99"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="143"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="192"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="217"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="301" mass="33894" checksum="F27888D811872486" modified="2015-04-01" version="1">MVINFLSKACLFIDHKADYIPIASTVVNLVNIFQKVIVLPLKEKENLSRNPYYTHLKQKTFKRCAILLIPVLGNILVGIWNFAPSKEDDKDALCAAIRSVQHNGMALKYASPELRNVKQVVLAAVQQNGKALKYASPKLRNVKQVVLAAVQQDGKALKYASPKLRNVKQVVLAAVQKCSWALEYAGEDLRNDRKFFLAVVRQHGNDLRHASEKLRNDKEIVLAAVQEWGWALRHASKKLRNDKEIVLAAVQQDGSALEYASEELRNDREVVIAAVKQYGPALKHASEKLRNDKEVLRCLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA42</accession>
    <name>A0A0C1KA42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease R</fullName>
            <shortName evidence="5">RNase R</shortName>
            <ecNumber evidence="5">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rnr</name>
        <name evidence="9" type="ORF">DB41_GR00090</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384847.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75997">
        <property type="protein sequence ID" value="KIC75997"/>
        <property type="gene ID" value="DB41_GR00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1005"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01895">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004476">
        <property type="entry name" value="RNase_II/RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011805">
        <property type="entry name" value="RNase_R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00358">
        <property type="entry name" value="3_prime_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02063">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CSP" evidence="7">
        <location>
            <begin position="94"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="RNB" evidence="8">
        <location>
            <begin position="274"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="727"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="770" mass="87686" checksum="C489CDFD4C7A7C95" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAI7</accession>
    <name>A0A0C1KAI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA gyrase subunit B</fullName>
            <ecNumber evidence="10">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">gyrB</name>
        <name evidence="12" type="ORF">DB41_GN00120</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384785.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76102">
        <property type="protein sequence ID" value="KIC76102"/>
        <property type="gene ID" value="DB41_GN00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.973"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="441"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="834" mass="94408" checksum="0F9291F981070780" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBE9</accession>
    <name>A0A0C1KBE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GA00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76477">
        <property type="protein sequence ID" value="KIC76477"/>
        <property type="gene ID" value="DB41_GA00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="16324" checksum="D605FC1A3754E79D" modified="2015-04-01" version="1" fragment="single">CKNITALNLSRAGLTYLPSEIGQLPQLQKLDLRDNQLTSLPAGIGQLSQLTRLHLNRNQLTALPAEIGQLSELQWLDLRENQLTALPAEIGQLSKLEALHLNQNKLTALPTEVGQLSQLTKLELAGNPLKDIAEKIRQRFHLQSGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC81</accession>
    <name>A0A0C1KC81_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">uppP</name>
        <name evidence="15" type="ORF">DB41_EY00230</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384009.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76712">
        <property type="protein sequence ID" value="KIC76712"/>
        <property type="gene ID" value="DB41_EY00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.600"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC76712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="30062" checksum="B4B6799DEE694A7B" modified="2015-04-01" version="1">MSTIEAIFLGFIQGITEFLPVSSSGHLILAQYLLGMNNFKDLITFDLICHLGTLLALFIAFFKKIKTLLTSEKKVLYFLFIALLPLFPLVFFLQFIKAFFDHIEYLGYFFLFTAALMYLGVCLSKKTSSVTEMSKHTWKEALMIGFFQAMAVFPGISRSGATISAARLLGWNYEHAITFSFLLAIPTLMASIIVELGQLILKRDNYSLPAISWVQYLAGFFFSFLFGIIALHYLQKLASKRLFMYFIGYCLLVGMVTTLFFRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCG5</accession>
    <name>A0A0C1KCG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heptose adenosyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hldC</name>
        <name evidence="2" type="ORF">DB41_EJ00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243805.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76782">
        <property type="protein sequence ID" value="KIC76782"/>
        <property type="gene ID" value="DB41_EJ00120"/>
    </dbReference>
    <dbReference type="GeneID" id="39482470"/>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.527"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="1">
        <location>
            <begin position="37"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="18720" checksum="F9FC04DC8B191782" modified="2015-04-01" version="1">MSKTWSIECLKKYITPLNLAQKIEELREQGQKIATVNGSFDLLHAGHLQILFEASQQADILIVALNSDQSIKQYKSPWRPIIPLEFRLQMMSALSFIDYVTWFEETNPIELLKIIKPDVHVNGSEYGENCLEAETVRASGGRLHLVNLIPGLSTSQILKKISSLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCI0</accession>
    <name>A0A0C1KCI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76792">
        <property type="protein sequence ID" value="KIC76792"/>
        <property type="gene ID" value="DB41_EI00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.490"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4861" checksum="0367476F4B0FAE44" modified="2015-04-01" version="1">MSRLKKNYLEKVKPALQEKFGYTNPMNIPGLKKNRGQYGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCX2</accession>
    <name>A0A0C1KCX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rpsJ</name>
        <name evidence="7" type="ORF">DB41_DT00060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042236533.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76912">
        <property type="protein sequence ID" value="KIC76912"/>
        <property type="gene ID" value="DB41_DT00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.395"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="6">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="118" mass="13490" checksum="03D4B80DA2EB048A" modified="2015-04-01" version="1">MAKQQEKQIKQEKVHKPARQKIRIRLKGYDQRILDRSTEDIVETAKRTGAAIAGPIPLPTRIVKFTVLRSPNIDRKSREQFEMRTHKRLIDILNPTGKTIDALKTLTLPAGVDIKIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD35</accession>
    <name>A0A0C1KD35_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 14" type="primary">topA</name>
        <name evidence="14" type="ORF">DB41_DP00090</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383557.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76957">
        <property type="protein sequence ID" value="KIC76957"/>
        <property type="gene ID" value="DB41_DP00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.342"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SSF47592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="12">
        <location>
            <begin position="3"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="SWIB/MDM2" evidence="13">
        <location>
            <begin position="783"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="166"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="744"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="750"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="861" mass="98182" checksum="C68FCBDB68804689" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDD6</accession>
    <name>A0A0C1KDD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DM00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000029">
        <property type="protein sequence ID" value="KIC77022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77022">
        <property type="protein sequence ID" value="KIC77022"/>
        <property type="gene ID" value="DB41_DM00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="23736" checksum="3DCC5DA1E0FDF193" modified="2015-04-01" version="1">MPPTSTSSPNVNLCVIGSDNVKDAISGKLMTHAVALFPCGHTFNEDTVIQRLAGDKLCPVDGKLIERHAPNHTVRQIAATAELRPLESSREVYIERLINLLRELQIQENPTLKKMVELGDKIHALSPLSIPSLYRAIAHVHFPDRDGDVAEQVHSLDQIYRIESNLSVEEKVSCIFQRLFNLADSYSPLEGTSKNSKDFTLSNYSSYLLNIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDQ8</accession>
    <name>A0A0C1KDQ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="8">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">gltX</name>
        <name evidence="12" type="ORF">DB41_DB00140</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383357.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77107">
        <property type="protein sequence ID" value="KIC77107"/>
        <property type="gene ID" value="DB41_DB00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.205"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="3"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="11">
        <location>
            <begin position="334"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="250"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC77107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="505" mass="58879" checksum="C4F2C01910104AA6" modified="2015-04-01" version="1">MTVRVRIAPSPTGDPHVGTAYMALFNLIYARHHQGKFILRIEDTDRSRSRPEYEQNIYTALQWCNIQWDEGPDVGGPYGPYRQSERFEIYKKYAYELVDKGRAYKCFCTPADLEEMRELATKLGGRQGYDRRCRNLSAEEIHQRETQNLPYVIRLKMPLTGECVYEDHIKGRITCPWADIDDQVLLKSDGFPTYHLANVVDDYLMKITHVIRGDEWMSSTPKHIYLYEAFGWASPTFMHMPLLLGRDGKKLSKRRNPTSIFYYRDSGYLAEAFVNFMTLMGYSMPGDKEIYALDEIIQEFDYKRIGVSGAIFDVQKLAWINQQYLIKNIPENKLWERLRQWNFSDEYMQKLMPLCHSRIKTFGEFMELCDFFFINHLKYTPEIFTVKGIAYHQTPLILQGMIWHMDENENWGSTGINQASRSMAELFGVNHKKTIMPLLFASLMGKLQGPPLFDSAAILGKDRTRARFLESIEFLGGISNKKMDALKKAWQQKDARHLIELPESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDX4</accession>
    <name>A0A0C1KDX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CV00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77177">
        <property type="protein sequence ID" value="KIC77177"/>
        <property type="gene ID" value="DB41_CV00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5525" checksum="39F2614A188ED306" modified="2015-04-01" version="1">MLSNMINIGFLKRKFHFFLETISNKKVIELTDYACYRRFFLVTTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE83</accession>
    <name>A0A0C1KE83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">mutL</name>
        <name evidence="8" type="ORF">DB41_CK00100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77282">
        <property type="protein sequence ID" value="KIC77282"/>
        <property type="gene ID" value="DB41_CK00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.24"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_mis_repair" evidence="7">
        <location>
            <begin position="263"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="6">
        <location>
            <begin position="463"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC77282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="656" mass="72644" checksum="F3411BE4DAABF39A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE97</accession>
    <name>A0A0C1KE97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_CJ00020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243725.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77292">
        <property type="protein sequence ID" value="KIC77292"/>
        <property type="gene ID" value="DB41_CJ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024474">
        <property type="entry name" value="Znf_dom_IS66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13005">
        <property type="entry name" value="zf-IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="4">
        <location>
            <begin position="57"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="zf-IS66" evidence="3">
        <location>
            <begin position="133"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="2">
        <location>
            <begin position="193"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="470" mass="53685" checksum="7272B6105443EAAF" modified="2015-04-01" version="1">MELENTFSLNKKFNIMIGMINKPEKPTAIRSDVFTSLPQEVQAYIQLLEKQVVVLMHQVEKLVAKVGELEARLTKDSSNSHKPPSSDGLGKKPKTSSLRGKSDRNPGGQPGHTGRTLEQVLNPNYIEVHRLMTCEQCQSNLSKVEPSGFEKRQVFDLPKLVVEVTEHQAEIKQCPCCNHRAKGKFPENVKASTQYGERILSLAAYFEHQHLIPMKRIAQIFEDLYGLSLSAGTCQNTDKKLYKNLETFESNLKPHLLACKVLNFDETGMRCEKKLHWIHVTSSACATFYGMHHKRGQQALNDFAILPNFTGSAIHDHWSPYFTYQQVQHALCNAHHLRELKYVFEQEKGAWAQKMASLLLKANKMAKQTRDEGKGKMALQDIQIIQQEYAKIILEGLRDYQGVLMADEQEIKLQPFKEKVGKAGCNLLRRLLHKMDNVLAFVHNLQVPFTNNQAEQDLRMLKLDEILFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1S4</accession>
    <name>A0A0C1H1S4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AU00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71629">
        <property type="protein sequence ID" value="KIC71629"/>
        <property type="gene ID" value="DB41_AU00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="6436" checksum="A2ADF22801F712FC" modified="2015-04-01" version="1">MRNIIFEWQAIHLNHPKQRLRIYLTASLPRAKKINKTNDFPVTAVIPQSSYNGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1V6</accession>
    <name>A0A0C1H1V6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AR00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000214">
        <property type="protein sequence ID" value="KIC71674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71674">
        <property type="protein sequence ID" value="KIC71674"/>
        <property type="gene ID" value="DB41_AR00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4680" checksum="49D9A2E7920D2E04" modified="2015-04-01" version="1" fragment="single">HQLDNEIFHHLNLLLFQISLCPRSFLGTSILINLISKEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H294</accession>
    <name>A0A0C1H294_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0051 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB</name>
        <name evidence="3" type="ORF">DB41_AI00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386721.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71799">
        <property type="protein sequence ID" value="KIC71799"/>
        <property type="gene ID" value="DB41_AI00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2161"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="126"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="479" mass="53191" checksum="26512C201237D4AD" modified="2015-04-01" version="1">MATQEAFRGQSDYKYGFSTAVEMDSLPKGLNEMTIRAISAKKDEPQFLLDFRLKAYRLWLESTPPVWPNVHYPPIDFQNICYYSAPKTKAKYNSLDEVDPEILRTFERLGIPLDEQKRLTNVAVDMVFDSVSIGTTFKKNLEEAGVVLCSISEAINLYPDLVKKYLGSVVPIGDNFYATLNSAVFTDGSFVYIPKGVKCPMELSTYFRINDKESGQFERTLIIAEEGSSVSYLEGCTAPAYDNNQLHAAVVELVALDHAEIKYSTVQNWYAGNPKTGAGGIYNFVTKRGRCAGISSKISWTQVEVGAAITWKYPSCILQGDHSVGEFYSVALTNHHMQADTGTKMIHLGKNTRSTIVSKGISADTSHNSYRGLVKIVPRAHGARNYTQCDSMLVGDQCSANTFPYIEVGNSSSQVEHEASTSKMNEEQLFYMRSRGLSQEDAVNMIVNGFCKDVIKELPLEFAAEAQKLLTLKLENSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2X2</accession>
    <name>A0A0C1H2X2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O antigen biosynthesis rhamnosyltransferase RfbN</fullName>
            <ecNumber evidence="2">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rfbN</name>
        <name evidence="2" type="ORF">DB41_AD00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000204">
        <property type="protein sequence ID" value="KIC71964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386627.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000204.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71964">
        <property type="protein sequence ID" value="KIC71964"/>
        <property type="gene ID" value="DB41_AD00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="305" mass="34742" checksum="88F899E197276723" modified="2015-04-01" version="1">MKSVGVVVLTLNAEKHLVRCLNPIMQSSLSPKILVVDSSSRDQTRSLAYSLGVEVLSIPQATFNHGKTRELARKHLGTDLVVMLTPDAYAVNPQVLEKLVEPIIQGKASIAYARQIPHEGADFFESFPRYYNYPVRSEIRSIADRRRYGSYTFFCSDSCAAYLNSALDEVKGFRSVLLGEDTLATAQLLKIGHKIAYVAEAEVRHSHRYSLRQEFCRYFDTGLMRKKYENILNCAEDDQLRGNHYATCMLKQLYQEKPLLLPYALMHIGAKWAGYRLGQASINAPLWWKKALSSQKYYWKKITTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4C2</accession>
    <name>A0A0C1H4C2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KN00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000193">
        <property type="protein sequence ID" value="KIC72384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386426.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000193.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72384">
        <property type="protein sequence ID" value="KIC72384"/>
        <property type="gene ID" value="DB41_KN00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="109" mass="12690" checksum="D355584CA365417E" modified="2015-04-01" version="1">MLNEEEVNNVVNRLKNHPNLLESIRELLDITEGIKGIEVADDAEFALIPEVRGLGKKCLEDWAKHQVNEQEAKAQEMKLRLHSKKTKLAYNFWDIRYGREMLSTSRNID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5Q2</accession>
    <name>A0A0C1H5Q2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KC00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386274.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000184.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72814">
        <property type="protein sequence ID" value="KIC72814"/>
        <property type="gene ID" value="DB41_KC00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="510" mass="58216" checksum="7AF0349F051658DC" modified="2015-04-01" version="1">MRKYLFLSCVLFNCLFAEESTPLSVEAENMHYKGELVHLSGKVFLEHELGKVKAQEIIIFPAKETKKRSLSHLKMVQGAEIALQDGGQLSCSEAEIDAQNLVGKFLNGPNHEYVVYKENIKEKASLLTKPLEIKSHQLTIYLQRQEQEGKSSLFISEISASPNVTINYNHEIFAQADHGTYKRTKPPFVLDKQNTLQTKRVGILSLQANTSSGMCRLSNPKGDFINAQKIDWDVFRRQLEFDKPSGSLYTGTAYEPAHKINFSCAAMSWDEQQDILTLYQQIEIDYLGLGKLTTPEKVYISRHSIDASKQVSLIECRGPSVLQYQDKTKNLDYTLSTYHKLIVDRKLRQAHLESPRDANGQVMKGQQVHLTGSMGEMYADEVFIYYDEIAQQLKPVKLFLKGSVWLLKRKANDKEKQEQFSHLAISDRLEYNIETQEMLFLSDYGKRVLFLDGSNHLQISAPSVKVLKDPHTKKDRVQGIGDVRFNFIEKECKMLQERFPTFEAKIGIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H661</accession>
    <name>A0A0C1H661_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_3</name>
        <name evidence="3" type="ORF">DB41_JX00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000180">
        <property type="protein sequence ID" value="KIC72959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72959">
        <property type="protein sequence ID" value="KIC72959"/>
        <property type="gene ID" value="DB41_JX00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1838"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="494" mass="56008" checksum="AFC8BF930C7299F3" modified="2015-04-01" version="1">MPTEIGQLSELQYLYLNQNQLTALPAEIGRLSQLEWLDLNQNQLTSLPAEIGQLSKLQHLYLNQNQLTSLPAEISQLSQLQELHLNQNQLTALPAEIGQLSELQTLDLRENELNNLPAEIGRLPQLQWLDLSQNQLTSLPEEIGRLSQLQELNSSQNQLTSLPAQIGQLSQLQTLDLRENQLTSLPEEIGQLPQLQWLYLNQNQLTSLPAEIGQLSQLEWLDLNQNQLTSLPAEIGQLSELHTLELNQNQLTSLPKEIGQLSKLQVLYLNQNQLTALPPEIGQLPQLQWLYLNQNQLTSLPAELWQLSELQSLELNQNQLTSLPAEIGQLSKLQVLYLTQNQLTALPPEIGQLSELTRFFLTQNQLTSLPAETGQLSQLQYLFLNQNQLTSLPAEIGQLSELQYLYLNQSQLTSLPAEIGQLSQLQSLELNQNQLTALPAEIGRLSKLRWLKLNQNQLTSLPTEIEQLSNLYELELAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H7X9</accession>
    <name>A0A0C1H7X9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JI00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000165">
        <property type="protein sequence ID" value="KIC73519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73519">
        <property type="protein sequence ID" value="KIC73519"/>
        <property type="gene ID" value="DB41_JI00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10694" checksum="A2ABECDEE3A1F42A" modified="2015-04-01" version="1">MQVINFKKGNISLYIHAVNGINSDQTAPTSLIAKHPTKKFALGKREPLYSSRQCSLYPDTFYISLKESTELICHAYAHANYYNIFKANVYWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9Y6</accession>
    <name>A0A0C1H9Y6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AS00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71648">
        <property type="protein sequence ID" value="KIC71648"/>
        <property type="gene ID" value="DB41_AS00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="368" mass="42136" checksum="6CC3C4496BAE1B16" modified="2015-04-01" version="1">MDNQLIKHNTRVNNMVVKEIPLDNPVPLLREQTIQVNAKIAQLEQDAAIQNVIDQMFAMDIRQMENERIRLSNIVHLQHAELSREFKQRRIEVEEVTAILDITLENLAASNENSSKLMQAQLQLKKDFKLIRNQQAELKKAFKLIEQDHAQIAEDHAQIAKDHDQIANDQADIAKDQAKIRQEQQQIRGNLERLEEGRVSLSKSFASLKISFKEISRQLDTMLEERLLHQQDADLSEKEIEEKAAVKRNEITKQYMQDWEDEIQREYDENKALNSQSTQEFAEQLEDSILNAEEIAARGETSFLSTAQQTQGSEALKSPGWLGALKHKMGTWKHTALKVTEFFTRSACLATIVSVGLTSLFAIKATLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAK2</accession>
    <name>A0A0C1HAK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74419">
        <property type="protein sequence ID" value="KIC74419"/>
        <property type="gene ID" value="DB41_IP00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4923" checksum="C62955D3D2FD580D" modified="2015-04-01" version="1">MFYRRKEPCYVNGLIACLLKEESCTKLITKVSIHCSLDMASRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAY3</accession>
    <name>A0A0C1HAY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244092.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71948">
        <property type="protein sequence ID" value="KIC71948"/>
        <property type="gene ID" value="DB41_AE00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2140"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="308" mass="34143" checksum="2A8D1783F749E334" modified="2015-04-01" version="1">MRDEEAAIEGLPLANALDHAILIHREVHFGGKFDVMLDYYLNEGKGVNPEFELERIHTLAKIEKKMKTDLAPLMLAGAEAEKIAEAKTAYKKLRSLYEKPKPAMKNMLLVADLILSEDLEAAQEIEAIVQEKGAIVPALIELLKAEEFYDPLFPGYGLAPSLAAKCLGMIGDKRAIIALFESLSQGDFFEEDIVLAALRAIGKPAKEFLLKVVHGRPINEDNERAAIALIAFKEEEDVSKACLEMLRDSQVRKDIPLATYLILACEGLKSLEDRTAFQLLAQESGMPKMLMQDIHAVASLWDTSPSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAY6</accession>
    <name>A0A0C1HAY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74559">
        <property type="protein sequence ID" value="KIC74559"/>
        <property type="gene ID" value="DB41_IJ00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6743" checksum="C4403BF916957763" modified="2015-04-01" version="1">MKEGQIVKELKPNKKRKQSRSRSLKFMSSFEKPAKCKALKLYLRFAEVKENNLLRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB63</accession>
    <name>A0A0C1HB63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hamA</name>
        <name evidence="8" type="ORF">DB41_AA00140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386561.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72033">
        <property type="protein sequence ID" value="KIC72033"/>
        <property type="gene ID" value="DB41_AA00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2086"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="156"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="22949" checksum="399700FDD95A899B" modified="2015-04-01" version="1">MELILATQNVHKIRELRDMLKSFKEVAHLDILSLLNFPDYEALPEEGLSFKENVERKALHAAKKLGKWVLADDSGLVIPALKGAPGIYSARYSGLEATDGENRQKLLAEMHGLEDIERTGYFECWLSLASAEGIKKSVHATCEGLIINQERGRHGFGYDPLFIKHDYDKTFAELDEQTKNRISHRRKAIEKLIPSLEMLRDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCG9</accession>
    <name>A0A0C1HCG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75089">
        <property type="protein sequence ID" value="KIC75089"/>
        <property type="gene ID" value="DB41_HW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7622" checksum="26926C83E3C610A5" modified="2015-04-01" version="1">MHEKPPLGKEIEKINSKSLFPLMRFIEHEKFFLFSTAIAKTLMNKVWKIDEQGLARICKRKQGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEU3</accession>
    <name>A0A0C1HEU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphocarrier protein HPr</fullName>
            <ecNumber evidence="2">2.7.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ptsH_2</name>
        <name evidence="2" type="ORF">DB41_GU00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243910.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75959">
        <property type="protein sequence ID" value="KIC75959"/>
        <property type="gene ID" value="DB41_GU00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="9"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="97" mass="10734" checksum="08B5D27A730E2DDF" modified="2015-04-01" version="1">MAKLTNNKRHTGIFIVQNDRGLHTRPSTEIVKCATSFRSEVHLIYQKSYVNAKSLLGILMLAATKGSKIQIEAEGEDAEEAVASLIALAKNNFNIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HF07</accession>
    <name>A0A0C1HF07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phosphoketolase</fullName>
            <ecNumber evidence="3">4.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JL00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000168">
        <property type="protein sequence ID" value="KIC73288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73288">
        <property type="protein sequence ID" value="KIC73288"/>
        <property type="gene ID" value="DB41_JL00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1776"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PTHR31273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="XFP_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="465" mass="52277" checksum="46A8E7B94F4DF758" modified="2015-04-01" version="1">MVREIPSTICQGGPLTEEELYKMDAYWRASNYLSVGQIYLLDNPLLKRPLTIEDIKPRLLGHWGTTPGLNFIYVHLNRLIKARDLNMIYLAGPGHGGPGLVANVYLEGTYSEYYPNISSDEEGLKKLFKQFSFPGGIPSHVAPETPGSIHEGGELGYVLSHAYGAVFDNPDLIAACVVGDGEAETGPLAASWHSNKFLNPAKDGAVLPILHLNGYKIANPTLLARISPEELKSLFEGYGYKPYVIEGSDPYQMHQNMAHTLDIVIAEIKKIQEDARKNQLIERPRWPMIILKTPKGWTGPQEVDGKKTEGFWRSHQVPLSNMAVKPAHIQQLEKWMKSYRPEELFDEDGRFLAELAALAPQGKRRMGDNPHANGGLLRKELKMPDFREYTLEIEKPGQVEAESTRIMGKFLRDVMKNNLHNFRVMGPDETASNRLDAIYEVSKKVGWLIIFPKMKMVVSYLPRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGS7</accession>
    <name>A0A0C1HGS7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">glmS</name>
        <name evidence="11" type="ORF">DB41_IX00020</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="JRXI01000155">
        <property type="protein sequence ID" value="KIC73878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386073.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000155.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73878">
        <property type="protein sequence ID" value="KIC73878"/>
        <property type="gene ID" value="DB41_IX00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1690"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="287"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="458"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC73878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="609" mass="66864" checksum="96421A3459DE86C4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHT8</accession>
    <name>A0A0C1HHT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DZ00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76884">
        <property type="protein sequence ID" value="KIC76884"/>
        <property type="gene ID" value="DB41_DZ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.425"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025159">
        <property type="entry name" value="AbiEi_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13338">
        <property type="entry name" value="AbiEi_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="24403" checksum="6F0D9C8B6B3F62E1" modified="2015-04-01" version="1">MLLGFSVKFPIKRLTMKKLTTLHSLHSLLTRPFFTVAQIKQLGISPARLAYYIRKKQIKRLGRGIYQSSDYQGSPEIFQWEDLIEAVNSVPGGVICLVSALAIYELTEEIPRKHWIAISHSTSITREGSIKIVRFRNMELGKTEVELGGIRLPIFDRERTIIDAFRLLSRETAIKALKMALLKKGNKIDLKRLQTYAKKLRFNIDPYLITATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKM8</accession>
    <name>A0A0C1HKM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative branched-chain amino acid transport system II carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">braB</name>
        <name evidence="9" type="ORF">DB41_HY00340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the branched chain amino acid transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243964.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75008">
        <property type="protein sequence ID" value="KIC75008"/>
        <property type="gene ID" value="DB41_HY00340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1427"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004685">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_Livcs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30588">
        <property type="entry name" value="PTHR30588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05525">
        <property type="entry name" value="Branch_AA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="375" mass="40779" checksum="BD89F88079696CF6" modified="2015-04-01" version="1">MRISLHLKTIATGLAMFSMFFGAGNVIFPLAIGHYAQDKTFFAILGLLITAVLVPFGGLFAMLLFEGDHKRYFAVLGKFPGFLIALFIITLLGPLGSLPRCIALASSTVRMSVGDFSPVAFNALACGLIFFFTYQKRYIMEWLGYILTPLLLGSLAYIITKGLLTAEVSSFSPQQQPSLTVFLEGLKEGYNTMDLLAALFFSSIIFNSLKNTLALYPQESLVKIGLRSCALGAFLLALTYIGFSYVASFHSAKLKVESVEQLLGAITMEIIGPSAGIWVCSTIALACLTTAIALSNVFADFISHTVFQNKISYKTALIGTLLATFIVANLQFAGISAFLIPILKVCYPFLMLLTVYNIVTQIFARKTLSIAQAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL33</accession>
    <name>A0A0C1HL33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HW00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75108">
        <property type="protein sequence ID" value="KIC75108"/>
        <property type="gene ID" value="DB41_HW00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="8065" checksum="55A98C73740B1CCC" modified="2015-04-01" version="1">MWPYSSLIFLSHLKMLRAGRINFSTFLGQPLIICIIYTPEEGASTYYIVLGNLKNSFQKTMDGKNDCYHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN18</accession>
    <name>A0A0C1HN18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HH00310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385237.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75738">
        <property type="protein sequence ID" value="KIC75738"/>
        <property type="gene ID" value="DB41_HH00310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="100" mass="11301" checksum="2098190A6156F8C4" modified="2015-04-01" version="1">MIGLLCEVASPLFFRVYIPVTWQAIGYLKIKAVRKETNEAAEAIRECIKTQVWMLKYSPSEGLMACKLLSHRIAASFISDVDLPSFEKGYIFLLDKLQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNJ3</accession>
    <name>A0A0C1HNJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal RNA large subunit methyltransferase K/L</fullName>
            <ecNumber evidence="4">2.1.1.173</ecNumber>
            <ecNumber evidence="4">2.1.1.264</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rlmL</name>
        <name evidence="4" type="ORF">DB41_GZ00370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.173" evidence="4"/>
    <dbReference type="EC" id="2.1.1.264" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75873">
        <property type="protein sequence ID" value="KIC75873"/>
        <property type="gene ID" value="DB41_GZ00370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1102"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052915">
        <property type="term" value="F:23S rRNA (guanine(2445)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="48"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="380" mass="42470" checksum="D40C5711BAAAE146" modified="2015-04-01" version="1">MLENPNHLFVTCGQGLESLLIQELAELGFTQVREGFRGVYVFDKSFPAIFRLNYCSRIAGRVLLPLAQFPCYDQKGLYKGGSSIDWLKYLPSGKNFAIDANVSHRQLKNSLFAAQVLKDAICDQIRAKTGNRPSVNVKNPDVQLNLFIHDNQATISVDTSGTPLHKRGYRQESAEAPLQESLAAALLRLADYQPHEILLDPCCGGGTLLIEAALIASRTAPGYLRQKWGFMLLPHFSFEEWLKVKTEVDALRQAIPKNHLFGIDINKNVARICQGNLRAAGFLKDVLVKQADFREFSPSILPTMILTNPPHGKRLDNVDTLIPLYRALGDFMKHHVSKPARGFIFTANTPLVKEIGLSASRRHVITNSSVDSRLLEFDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQ09</accession>
    <name>A0A0C1HQ09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin-like_fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GK00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243883.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76288">
        <property type="protein sequence ID" value="KIC76288"/>
        <property type="gene ID" value="DB41_GK00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="2">
        <location>
            <begin position="191"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="346" mass="39335" checksum="79EDC08D0886B800" modified="2015-04-01" version="1">MSTNHSLIPKDLPANKYQKYLHAISSLAIIAGWIFSIISWLQICTQECAATHDYRLFGFQLEYIGMIFFPVLSLLHWGAYYKKNLSFMAAIILAGALGAEIVFIYAQKVWIGQWCPLCLCIAASIVITSLAYLLSYFNHYRRSLSESKRIKMALNIPKVLAIVVALITGFFIASLGLAKVDELQAAENSIKNSIVFGNLNSKIDAYFFSDWHCPACRQLEPKLKELVPTLMKNTRLTYVDFAIHPSSLNFTPYNLSFMVHDKNKYLELRDSLTQLSSDTETPTDEQIEKIAKEQDAHYTQLNYSEVALGLEYFKTLATEFDIDSTPTLVLVNEKTKKVKNYMASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQG8</accession>
    <name>A0A0C1HQG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein YbfM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ybfM</name>
        <name evidence="2" type="ORF">DB41_GD00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76433">
        <property type="protein sequence ID" value="KIC76433"/>
        <property type="gene ID" value="DB41_GD00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.873"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="201" mass="22707" checksum="28CC434F4CDD57BA" modified="2015-04-01" version="1">MNDTFSLWLLEYGSMALFFLLALGIVALPIPDETLMVISGVMIHQGHLYTIPTLMAAYLGSMCGITLSYMLGKTAGHFIIKKYGKWIGINEVRLKKAHDWYEYLGKWTLTFGYFIPGVRHLTGVLAGMTELTYTSFALFAYSGAFLWATVFLSIGYFFGPYWSCVLCFLDDHPLELIIAGISILLIIWLSKRRDKSKTVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQJ8</accession>
    <name>A0A0C1HQJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycine-rich RNA-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grp2</name>
        <name evidence="3" type="ORF">DB41_GC00250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76458">
        <property type="protein sequence ID" value="KIC76458"/>
        <property type="gene ID" value="DB41_GC00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="118" mass="13138" checksum="9E563B8D7BEBCA55" modified="2015-04-01" version="1">MKKIFVGNLSWKASEETLKPLFEAFGTVVSIKIIKDQYTGKSKGFGFVEMETDDEAAKCIHELNEKPFLERNLRLSPAQERQAGAGGGRDNRSPRGNGGDSYHRGGQRSNRDRSFASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQU3</accession>
    <name>A0A0C1HQU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Insertion element IS402 uncharacterized 16.2 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FR00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000079">
        <property type="protein sequence ID" value="KIC76538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76538">
        <property type="protein sequence ID" value="KIC76538"/>
        <property type="gene ID" value="DB41_FR00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.753"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="15932" checksum="86322418F1BA156B" modified="2015-04-01" version="1">MSNAYPSHLSDREWEAIKIYFEVDYSKGGRPFKHTKRELLEAIFYVLRTGCQWHYLPKDFPHWKTAYTYFKKWKDAHLFEKINHHLRKKLRVIMGRNLDPSAAIVDSQSVKTVESGGFQVMMELKRLRDVKGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR55</accession>
    <name>A0A0C1HR55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Type-5 uracil-DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">DB41_FI00080</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76598">
        <property type="protein sequence ID" value="KIC76598"/>
        <property type="gene ID" value="DB41_FI00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.681"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033958">
        <property type="term" value="F:DNA-deoxyinosine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10031">
        <property type="entry name" value="UDG-F5_TTUDGB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044147">
        <property type="entry name" value="UdgB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="51"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="228" mass="25982" checksum="E115F4E1373C97F1" modified="2015-04-01" version="1">MATKTNNLSMWKNFQAVVINCRKCPRLVAHRETVPARPLYQHQKYWRRPLPGFGDQQAWLLITGLAPAGDGGNRTGRVFTGDATARFLVKALYAQGWANQPISESLDDGLILKDCYLTAAVKCFPPKHKPTRQECVNCHPYYMQEIEMLFKLRVILVLGKLAFDAFLLALKKKGLSTKGIKFKHGAFYRLENGLKLYCSYHPTPRNVNTGTLTEKMFYDLLEEIKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRH1</accession>
    <name>A0A0C1HRH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hyperosmotically inducible periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">osmY</name>
        <name evidence="3" type="ORF">DB41_EU00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383961.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000059.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76728">
        <property type="protein sequence ID" value="KIC76728"/>
        <property type="gene ID" value="DB41_EU00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="57"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="130" mass="14561" checksum="58DC11EE4060EA72" modified="2015-04-01" version="1">MKKVFLMTLLSLAVISCDTKDKSVPSSPKGEPSDYLRDKADRYAVEKTPLDQSESEADRTITQKIRQAIVKDDSLSMNAKNIRIITIDGVVTLRGPIATLEEREIIIGKTKEIPGIRKIENQLEITGKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRR7</accession>
    <name>A0A0C1HRR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <shortName evidence="12">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
            <ecNumber evidence="4 12">3.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">lpxC</name>
        <name evidence="13" type="ORF">DB41_EH00020</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the LpxC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4 12"/>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243801.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76818">
        <property type="protein sequence ID" value="KIC76818"/>
        <property type="gene ID" value="DB41_EH00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.469"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="292" mass="32489" checksum="B8774F88F3F9D6FA" modified="2015-04-01" version="1">MIGLKQNLISKYRQQRTLKNSISFSGIGIHTGKEVQITFVPAPENAGITFCRVDLPDRPRIPASVNYVYETSRSTSIGINNVVIHTIEHVLAAVRANNIDNLCIEIKGIEPPAANGSSDAFVNMIEEVGILEQAEQKPVIKIQSPIHWNQEDTYIMAFPYDGYRISYTLNYPHSKLLNCQFYSLEVNSYNFKHEIASCRTFALYKEVAYLLDHGLAKGASLDNAVIIHEEAAFSKGGLFFPDEMVRHKILDMIGDLSLVGIEFEAHVIALRAGHASNCAFAKELLNSITECA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRS3</accession>
    <name>A0A0C1HRS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EH00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76823">
        <property type="protein sequence ID" value="KIC76823"/>
        <property type="gene ID" value="DB41_EH00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="6056" checksum="5B274BBA4EF6C8D7" modified="2015-04-01" version="1">MQIISNETSPQEQLFFIKKIIRKIKGQRIKSLQKKQVPLLAIIERMSLNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSA0</accession>
    <name>A0A0C1HSA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383572.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76968">
        <property type="protein sequence ID" value="KIC76968"/>
        <property type="gene ID" value="DB41_DP00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="582" mass="65390" checksum="C649A62144AE9A5B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSU8</accession>
    <name>A0A0C1HSU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsp</name>
        <name evidence="5" type="ORF">DB41_DB00150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383359.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77108">
        <property type="protein sequence ID" value="KIC77108"/>
        <property type="gene ID" value="DB41_DB00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.206"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040573">
        <property type="entry name" value="TSP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17804">
        <property type="entry name" value="TSP_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="233"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="649" mass="73825" checksum="91A3571FD3CE7A7B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSW7</accession>
    <name>A0A0C1HSW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <ecNumber evidence="4 8">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ispF</name>
        <name evidence="10" type="ORF">DB41_CX00040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="4 8"/>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383297.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77138">
        <property type="protein sequence ID" value="KIC77138"/>
        <property type="gene ID" value="DB41_CX00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.157"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="9">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="165" mass="17575" checksum="04C4FAD000B1B052" modified="2015-04-01" version="1">MIVRTGIGQDSHRFLPVETSKPCIIAGLIFEHTPGFNANSDGDIVFHAICNAISSLSGVLILGNIADELCLKDGITDSEVYLLEAIKTLGAQKVTHVSITLEGKKPKFIDRIQAMRENIARVMQIELSQVGITATSGEGLTDFGCGEGVQCFAIVTTCQPTALSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSY2</accession>
    <name>A0A0C1HSY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">cmk</name>
        <name evidence="10" type="ORF">DB41_CW00070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383280.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77158">
        <property type="protein sequence ID" value="KIC77158"/>
        <property type="gene ID" value="DB41_CW00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.149"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="3"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="25894" checksum="46CFA69BA66855B7" modified="2015-04-01" version="1">MIITIDGPIATGKSTIAKTLAREIGYIYFDTGAMYRCLTYGVLKKDINVDDREQLNDFLHTFKFDIKSKHGKKHYYVGNEDVTDAIRLDKVTSHVSSISAIPMIRDKLVAMQRELAIGVNAVFEGRDMGTIVFPKAEIKIYLTGRPEVRAKRRYEELKRKYPEETRELTIEKSLEDLNRRDHLDLTREISPLKQAPDALVIDTSDLSIQEIIYKILEFKDLNIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT02</accession>
    <name>A0A0C1HT02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative competence-related protein comF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">comF</name>
        <name evidence="1" type="ORF">DB41_CT00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243748.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77188">
        <property type="protein sequence ID" value="KIC77188"/>
        <property type="gene ID" value="DB41_CT00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="239" mass="26888" checksum="4DC98B9BF1E19A74" modified="2015-04-01" version="1">MAKLGNILAAFVDFIYPLRCMHCATPVCHGKGGLCFKCALQLTLINMEERCPCCFSAEYEPEHRICYLCFMQPPVLKKYAAAFDDQDVAASLINKLKYANQPYLAQGAAAYMVLQLLNLKWPLPDLIVPVPLTFTQRISQGYNASLLLAESLGEIVKRPVQSLLYKSLWNEDYEGKAKQRGNYLNANSFLLKKEINVQDKVILLVKDKVRTGHTLNCCAEVLYEGFPKAIYGLSFCKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT12</accession>
    <name>A0A0C1HT12_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">gcvH</name>
        <name evidence="6" type="ORF">DB41_CS00100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77203">
        <property type="protein sequence ID" value="KIC77203"/>
        <property type="gene ID" value="DB41_CS00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.112"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="31"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="14800" checksum="0FDCF27FD00C710D" modified="2015-04-01" version="1">MQIKTIKNAFFLGEKMKFADTHEWIEVANRIGIVGVSKHAQKELGEIVYVELPKIGKKVTAGEEAAVLESTKAATDIYSPVSGTIIEANTALSSAADLVNTSPEKEGWLFKIEMDSLDELNKLMEAQEYYAKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJ92</accession>
    <name>A0A0C1JJ92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BG00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000227">
        <property type="protein sequence ID" value="KIC71435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71435">
        <property type="protein sequence ID" value="KIC71435"/>
        <property type="gene ID" value="DB41_BG00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="299" mass="34071" checksum="56D45495CB0D35B5" modified="2015-04-01" version="1" fragment="single">MHPISSASIESLPNELLLPILEACAVPSLFSVCKRWHHLLATEVMPFLYKQIGKVHVPQGNAKERALIVDRIYKLEEKLSETVKVNAIFRQIFTLAKSLSTLEFKEKTEEKRGLTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEKKGELLREWIEENCKNITTLDLSGVGLTCLPSEIGQLSQLIRLYLSQNQLTALPTEIWQPPQLQELYLNQNQLTSLPVEIGQLSQLQTLDLNRNQLTSLPAEVGRLDQLQWLYLSQNQLTALPTEIGQLSQLQGLYLNQNQLTALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK47</accession>
    <name>A0A0C1JK47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Type 3 secretion system ATPase</fullName>
            <ecNumber evidence="7">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">yscN</name>
        <name evidence="10" type="ORF">DB41_AS00140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386800.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71660">
        <property type="protein sequence ID" value="KIC71660"/>
        <property type="gene ID" value="DB41_AS00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2217"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013380">
        <property type="entry name" value="ATPase_T3SS_SCTN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022425">
        <property type="entry name" value="FliI_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03497">
        <property type="entry name" value="FliI_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02546">
        <property type="entry name" value="III_secr_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="AAA" evidence="9">
        <location>
            <begin position="160"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC71660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="438" mass="47610" checksum="EBD869DA9B9CBAC4" modified="2015-04-01" version="1">MSLDDKFDKLLGSIDELELTTVNGRITEIVGMLIKAIVPNVKIGEVCLVKREGEPLRTEVVGFTREEVLLSPLGEMKGIGPSSEVIPTHMPLHIKVGPNLLGRVLNGLGEPLDVETKGPLEVDEIYPVLQAPPDPVKRKRIESPLSVGVRAIDGVLTTGLGQRVGIFAAAGGGKSTLLGMIARNARADVNVISLIGERGRELRDFIEKDLGPEGLARSVLVVSTSDQASQLRLNAAYVGTAIAEYFRDQGKSVILMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPKLLERAGNSDKGSITAFYTILVAGDDMNEPVADEVRSILDGHLILSADLARQYHYPAIDVLSSASRVIMSIVPKDHLQLVGKLKEVLANYKKNELLIKIGEYKRGADKAGDFAIDYIDKVNRFLKQGVEEKCSFEETYQLLKNLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKA3</accession>
    <name>A0A0C1JKA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AQ00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71720">
        <property type="protein sequence ID" value="KIC71720"/>
        <property type="gene ID" value="DB41_AQ00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5660" checksum="5C321315C4D3207F" modified="2015-04-01" version="1" fragment="single">MHPISSTSIESLPNELLLPILEACVVPSLFSVCKRWHHLLASEVMLLLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKA7</accession>
    <name>A0A0C1JKA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AP00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000212">
        <property type="protein sequence ID" value="KIC71725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71725">
        <property type="protein sequence ID" value="KIC71725"/>
        <property type="gene ID" value="DB41_AP00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2186"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="91" mass="10548" checksum="BE0D3F3148F4F4EB" modified="2015-04-01" version="1">MLYLKDNQLTTLPTEIRQLSQLKLLYLNQNQLTALPTEIGQLSQLRVLKLGQNQLTTLPTEIEQLSKLHTLKLAENPLKDIAKKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKX8</accession>
    <name>A0A0C1JKX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AE00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71940">
        <property type="protein sequence ID" value="KIC71940"/>
        <property type="gene ID" value="DB41_AE00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5535" checksum="3030D097BA6C861D" modified="2015-04-01" version="1">MLNLLKILFLILGALLRKSSLKALIFWTEERLKLRKRKVNKENLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNK5</accession>
    <name>A0A0C1JNK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KV00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000200">
        <property type="protein sequence ID" value="KIC72096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72096">
        <property type="protein sequence ID" value="KIC72096"/>
        <property type="gene ID" value="DB41_KV00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7369" checksum="3659E818F01B58CE" modified="2015-04-01" version="1">MHFISLDSDDFSVLLFFKGNIKKLKRQVKRIRILINEKQLTNDLPRFFSDRFTERGGLPSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNM5</accession>
    <name>A0A0C1JNM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tnp_DDE_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KU00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72121">
        <property type="protein sequence ID" value="KIC72121"/>
        <property type="gene ID" value="DB41_KU00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13737">
        <property type="entry name" value="DDE_Tnp_1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="101" mass="11818" checksum="326649454E99AF5E" modified="2015-04-01" version="1">MIRAVYHLPFRTLRGFLLSLITLLALGLPVRCYTRICRRAKELGQELKKLSRKRPTDIVFDSTGVNVYGEGEWKVRQHGKAEDLEKDSLKRLPRLARDYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNX2</accession>
    <name>A0A0C1JNX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 17" type="primary">metK</name>
        <name evidence="17" type="ORF">DB41_KQ00010</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386468.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72236">
        <property type="protein sequence ID" value="KIC72236"/>
        <property type="gene ID" value="DB41_KQ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2004"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="116"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="235"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="166"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KIC72236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="393" mass="43270" checksum="0B960057C067C648" modified="2015-04-01" version="1">MKHSVFTSESVGIGHPDKVADQISDAILDACLEQDEDSRVACETMVTLGLVVVAGEITTKAQVDYQEIVRNTLKYIGYDQAQEGFDYRSCGVLTSIHKQSLDIAQGVNESEGLYKEQGAGDQGLMFGYACEETPELMPLPITLAHQIVRELHCIQQNKQLPYLRPDAKTQITIEYNEKHQPIRLHTVVISVQHAEEVKRETIVHDMKALVHRIAPKGFITDHTLFYINPTGRFVIGGPAGDCGLTGRKIIVDTYGGMGHHGGGAFSGKDPSKVDRSASYAARYVAKNIVAAKLARRCEVQISYAIGVAHPISIKIDTFGTGSVSENILSRAVPLVFDLTPKGIIQMLNLKRPIYRSTAFGGHFGRHEENFTWEKTDKIISLLECVKMESFAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRE2</accession>
    <name>A0A0C1JRE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JT00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000176">
        <property type="protein sequence ID" value="KIC73066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73066">
        <property type="protein sequence ID" value="KIC73066"/>
        <property type="gene ID" value="DB41_JT00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6357" checksum="3DF51E40C222A725" modified="2015-04-01" version="1">MIAHSIGYSAPCLIKTILPESQIANVLTANVSFKEEKEKDERYLMDIKEKESAPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSA1</accession>
    <name>A0A0C1JSA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IV00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000153">
        <property type="protein sequence ID" value="KIC74015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74015">
        <property type="protein sequence ID" value="KIC74015"/>
        <property type="gene ID" value="DB41_IV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5158" checksum="7A12C88233AB0FC8" modified="2015-04-01" version="1">MEKYSSTRLDHLKIGSTMSDKITQGMMIVQVVSSDPRAIMITGEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTM9</accession>
    <name>A0A0C1JTM9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">serS</name>
        <name evidence="10" type="ORF">DB41_IY00120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386084.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73816">
        <property type="protein sequence ID" value="KIC73816"/>
        <property type="gene ID" value="DB41_IY00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1705"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="138"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="231"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="349"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC73816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="425" mass="48577" checksum="6E7A72C17D00872B" modified="2015-04-01" version="1">MLDIKLLRKDAKGIEAKLKTKDPSINLTIVMDLDTQLRTLKTQLEALKATRNEFSQKIGEMRRFNQDASEMVKEVASMADEIHSLEHQCQQVEYSFNYEISKLPNVPMEDIKISADPKENVIFKEVGNKRDFDFAFKNHVELNEKLKLFDFERGAKISGSGWPVYRGLGARLEWALIQYMLSVQIKNGFEQWIPPLLVRREIAYGSGQLPKFENQQFKIHDEDYNLYLIPTAEVPLNGLHAQEILNPEELPLKYTAYTPCFRREAGAAGSNERGLIRVHQFNKVEMFCFCSPEQSPLLFEEMLNNAEEILQGLELHYRMALLVTGDMSYASARTVDIEAWLPGQNRYYEVSSVSNCTDFQARRSNIRFRSGKEGKPEFVHTLNGSGLATSRLMVSLLENNQNADGSVTIPKVLQSYLGVEKLVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTT9</accession>
    <name>A0A0C1JTT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_S9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IX00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000155">
        <property type="protein sequence ID" value="KIC73881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244004.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000155.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73881">
        <property type="protein sequence ID" value="KIC73881"/>
        <property type="gene ID" value="DB41_IX00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="247" mass="28125" checksum="AC84222927AF1687" modified="2015-04-01" version="1">MKRKEVIASPTTLPIYMQGEPLAAGPLPAFFYFALSAEESLYQEPYNQPILFLEKFPIRCYSFTLPFHGQGYDSNQALALWVQEFATHPHSFSHFLQSCIKNIEYLIQQGFVDEERIAVGGLSRGAFIATHLAAREPRLKYVLGFAPMTKLSSLEKTNNLEKEWDLHGLIYQLVNKQFRFYIGNRDNRVGTYACFDFIHQLAEAAYQQGHRSPAIELIISASIGYKGHGTLPPIFKEGAEWVKDKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUS8</accession>
    <name>A0A0C1JUS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IE00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000139">
        <property type="protein sequence ID" value="KIC74840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74840">
        <property type="protein sequence ID" value="KIC74840"/>
        <property type="gene ID" value="DB41_IE00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4734" checksum="246495DB93FB221C" modified="2015-04-01" version="1">MKSIFNLFLALSLKRKAAAFTYRIIDFSAENRFQLTENTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV14</accession>
    <name>A0A0C1JV14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IR00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386051.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74241">
        <property type="protein sequence ID" value="KIC74241"/>
        <property type="gene ID" value="DB41_IR00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002152303" evidence="2">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="77" mass="8565" checksum="0B3F7E1957C5F303" modified="2015-04-01" version="1">MKLKLVSILLYTMIPMLVTAAPAADQSAVTEEKVPFNLHSNPDTTDVFAIPLDSSEAELDGEEEELQELQKYDVKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVA0</accession>
    <name>A0A0C1JVA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative SufE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HY00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385546.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74985">
        <property type="protein sequence ID" value="KIC74985"/>
        <property type="gene ID" value="DB41_HY00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1406"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="PTHR43597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufE" evidence="2">
        <location>
            <begin position="16"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="141" mass="15813" checksum="9D17157EDFA6EC62" modified="2015-04-01" version="1">MSPTFERKQNELKALFVACPNEESKYKKIIEMGRTLTKPKLHRKTSENIVKGCQSAMYLHSFLKEGNVYFEVESEALISAGLAALLVYVYNGETPESILTCAPTFLEDLGIRASLTPSRANGLYSVHLRMKQDALRLLTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVH8</accession>
    <name>A0A0C1JVH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">secDf</name>
        <name evidence="9" type="synonym">secF</name>
        <name evidence="11" type="ORF">DB41_IP00110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386024.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74411">
        <property type="protein sequence ID" value="KIC74411"/>
        <property type="gene ID" value="DB41_IP00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1642"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1014"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1038"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1067"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1109"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1142"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1193"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1346"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1370"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1404"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1444"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1475"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC74411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1524" mass="170713" checksum="C88D1C4DA050C1F3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVP5</accession>
    <name>A0A0C1JVP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">V-type ATP synthase subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">atpE</name>
        <name evidence="2" type="ORF">DB41_HW00320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385510.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75120">
        <property type="protein sequence ID" value="KIC75120"/>
        <property type="gene ID" value="DB41_HW00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1388"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="208" mass="23497" checksum="07FCDD5DF4375E36" modified="2015-04-01" version="1">MKTLEKGQDKIKKISEQLRSEILEPAKEEAKKIIQEAEQKADHIIEEAEKHVETLIQAGRKTLEQERHVFHSSLQQASKQSVEALKQAIEHNLFNDQLNTLLNQSTINPRVIADLIAALIKAIEKEGLAGDLSVVVPHTVSTQEVNDLLADGILKRLKDQSVVVGDFKGGVRIKFIDKSLTIDMSDETLKDLISRYVRKDFRKFFFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVX8</accession>
    <name>A0A0C1JVX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yedO</name>
        <name evidence="7" type="ORF">DB41_IJ00170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385932.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74546">
        <property type="protein sequence ID" value="KIC74546"/>
        <property type="gene ID" value="DB41_IJ00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="PTHR43780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="6">
        <location>
            <begin position="34"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="322" mass="36470" checksum="FB85E6D595064CE0" modified="2015-04-01" version="1">MLFTLEKVVQQYIKLDFPLHSRIHKLKSYSSSHLHCYIKRDDELGLMGSKKRKFSSLMTFLIHQKAKTAIVIGGINSNHVLGISQLLIENQIQPFLFLCKSHQQRLKGNALLTQLLVPKHQIHWIERQDWPTVYKAALDFADLQGNQSTYIIPEGGCMPESFPGALTLPIDILYNELQEQIHFNHIFVDSGTGLTAIALIVGLAFLQHSAHVHVVLMAGKEDEFLDNLKCYHQHFEKLVKLPCRMPTHFSLCRPHQAKSFGATSAKTFKDIHEIAQTEGVLCDPIYNVKLFKEAQRIIQQKNLKGKALVIQSGGTLSLLGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW00</accession>
    <name>A0A0C1JW00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmA</name>
        <name evidence="7" type="ORF">DB41_IJ00420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385956.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74571">
        <property type="protein sequence ID" value="KIC74571"/>
        <property type="gene ID" value="DB41_IJ00420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1622"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="8928" checksum="9CB0C59981019F36" modified="2015-04-01" version="1">MAHKKGQGSTRNGRDSHSKRLGIKVGMGEIVKTGSVLVRQRGTKWHPGKNVGRGSDDTLFALADGCVSFRKSDRTYISIEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW78</accession>
    <name>A0A0C1JW78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IH00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000141">
        <property type="protein sequence ID" value="KIC74641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74641">
        <property type="protein sequence ID" value="KIC74641"/>
        <property type="gene ID" value="DB41_IH00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1564"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="190" mass="21120" checksum="77AC52449C4CAA75" modified="2015-04-01" version="1" fragment="single">GQLSELQELELNQNQLTALPTEIGQLSQLQGLYLNQNQLTALPIIIGQLSQLLGLDLSQNQLTALPAELWQLSQLRGLGLNNNQLTKLPNEIGHLSQLQTLELNQNQLTALPAEIGQLPELQALELNQNQLAALPTEIGRLSKLQELYLNQNQLTALPIEIGLLPELTKLELAENPLKDIAEIIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWG0</accession>
    <name>A0A0C1JWG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AV00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386883.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71567">
        <property type="protein sequence ID" value="KIC71567"/>
        <property type="gene ID" value="DB41_AV00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="320" mass="35717" checksum="1AC3E2BB64BE06DB" modified="2015-04-01" version="1">MKENNSEIQKARKNLAHALEAVKESYNRKNHGEFLTILGPLISSLSTVTMAQTIKEAAPALLLSFKIALQGIEKEESSAGIMGKALTSSTQRLVDFIVRIHLLQEDQGNKQLLLMISRGLVLTTIALSWALSDFRFTYSSPLKEKDEKEQQRKQSFGIELALILTLKTGIWQKIVESFVSACGATTKQQQTLTALILPLLLILSLLTVARGKKKFLEELFLHLKAELVEGLENLQTFLPSLAGELVSNIALYIQQATASLKEEDFDHLYQAYTGVLESIDATPSQLNEEIEEIIYFAETIYTAFRNGSIEFNHTTVSQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWZ4</accession>
    <name>A0A0C1JWZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="13">2.7.8.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pgsA</name>
        <name evidence="13" type="ORF">DB41_IB00890</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="13"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385782.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74956">
        <property type="protein sequence ID" value="KIC74956"/>
        <property type="gene ID" value="DB41_IB00890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1525"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC74956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="200" mass="22334" checksum="51A0ED20F30F6C25" modified="2015-04-01" version="1">MSIANYFTFIRIFISPIFLLVYLHHDYLEINPSLLPYVLLFLLGVSELSDAFDGYLARKYNQVTDFGKILDPMADSIARLSYFLTFTAEPVRLPLALIFIFVYRDSVVSTLRTICALKGFALAARTSGKIKAGIQAMAALTVLILMIPHSLGYLSSPDLQYISTWVVGIAGIYTAYSGVDYVYANRQYIAKLLSLHPAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXK7</accession>
    <name>A0A0C1JXK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">V-type ATP synthase subunit I</fullName>
            <ecNumber evidence="9">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpI</name>
        <name evidence="9" type="ORF">DB41_HW00280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385502.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75116">
        <property type="protein sequence ID" value="KIC75116"/>
        <property type="gene ID" value="DB41_HW00280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1383"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="PTHR11629"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="518"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="547"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="583"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="641" mass="73325" checksum="698343B10BEEF195" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXL7</accession>
    <name>A0A0C1JXL7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_HV00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75131">
        <property type="protein sequence ID" value="KIC75131"/>
        <property type="gene ID" value="DB41_HV00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1345"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="204" mass="22765" checksum="527BA9060D8C3A66" modified="2015-04-01" version="1">MQVLENADNRIEELKDKLELAKTKNNQRASQLSDSRRKAAVRLAAALKKELCSLNMPKVDFQIDIHPSKRNRYGDDKIEFFLLPNLGERRIPIKDCASGGELSRVMLSLQTVLSDKQRIPTLIFDEVDSNIGGATAAIVGEKLKAIGKDLQVLCITHFPQVAQHADYHLQISKKVVGDRTVTFVNLLDASTRKQELARMTGKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXM1</accession>
    <name>A0A0C1JXM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AC00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71982">
        <property type="protein sequence ID" value="KIC71982"/>
        <property type="gene ID" value="DB41_AC00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2103"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="534" mass="60333" checksum="8C6FAE038BA2C3B0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXM9</accession>
    <name>A0A0C1JXM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YieF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yieF</name>
        <name evidence="2" type="ORF">DB41_GZ00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75840">
        <property type="protein sequence ID" value="KIC75840"/>
        <property type="gene ID" value="DB41_GZ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1068"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="9"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="199" mass="22219" checksum="0B0C250824613D4C" modified="2015-04-01" version="1">MVIDMSKKPRILAFAGSLRKDSLNKKLIKIAAAGAQQAEAEVTLIDLKDYPLPLYDQDIEDQQGLPENALKLKKLMVQHDGFLIASPEYNSSIPAVLKNVIDWTSRKAEENEPFLSCFFEKPVALLSASPGQLGGMRGLVHVRSMFCNIFCYIIPQQKSISQAHLAFSEEGNLKNLKDQEDVLNVGRKLAQFIIKFNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXX1</accession>
    <name>A0A0C1JXX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AA00280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244086.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72047">
        <property type="protein sequence ID" value="KIC72047"/>
        <property type="gene ID" value="DB41_AA00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="520" mass="58737" checksum="597E07358A5E4A4E" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY70</accession>
    <name>A0A0C1JY70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS903 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72122">
        <property type="protein sequence ID" value="KIC72122"/>
        <property type="gene ID" value="DB41_KU00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="82" mass="9854" checksum="81A986E136E73142" modified="2015-04-01" version="1">MQTLGCDKCYFYLTTFSIKEIFYHTNLRRAKKLTYRIRNWSEYNKALVQRGSITLWFSDGTIKGWRENKSLRKEGAPKNLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYP5</accession>
    <name>A0A0C1JYP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KO00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386437.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72317">
        <property type="protein sequence ID" value="KIC72317"/>
        <property type="gene ID" value="DB41_KO00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="206" mass="23967" checksum="BA04C970E5F28FD6" modified="2015-04-01" version="1">MRIFLTLCLLLTALAACKGPQRSQAQSPISKDYSSDAFTRAAIRQATRLAHQHHWYLDDAWAYYNSTDSVHRLCLNFRTQNILELYQARAQLVDVVEELLQNLKSNPLTSSRLAPNFSAENLLIHVDFQSFWGLYGDSKYVGWMALENGMVYYYDFDVKNTQNDQWCNRIETYNKSKEIALIEKEAEKEYKDSLPAPKRGFEYLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ27</accession>
    <name>A0A0C1JZ27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76260">
        <property type="protein sequence ID" value="KIC76260"/>
        <property type="gene ID" value="DB41_GL00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.933"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="284" mass="33121" checksum="4A5D51B759877922" modified="2015-04-01" version="1">MDKAFEKPRKNLGESIRQRLKNLSEQRNRPFDEILRYYAIERFLYRLSLSPYAEKFFLKGGLMLKVWDSMDHRATMDIDLLARTSNQIDNLQRIITEVSEMSCEEDGISFDTQKLILRNTQTGGDYNGVSSSFSAKLFTTKMPVLIDIGFNDVIIPKPQRIQYPTLLGMPKPVLLGYTLETVIAEKLESIVKLALVNTRMKDFYDLWTILRHHEIKPEKLNVAIREVFANRKTPLQPPIAFTRAFYATKETQQRWNNFLSTMGKQQVKFEDVILELSSYVNNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZP2</accession>
    <name>A0A0C1JZP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenosine monophosphate-protein transferase FICD</fullName>
            <ecNumber evidence="5">2.7.7.n1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ficD</name>
        <name evidence="5" type="ORF">DB41_KD00020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386286.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72702">
        <property type="protein sequence ID" value="KIC72702"/>
        <property type="gene ID" value="DB41_KD00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1861"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="105"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="194"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="349" mass="40282" checksum="1277C623FF99AB8B" modified="2015-04-01" version="1">MPFHPNFTITIPLASALTAIERTRGFLEAAKLSENWLSKMQARALILEAHHTTHIEGTHLSLDQSKKLLSGVKMSDVNSEDVKELLNYKKAFDFVADYVFSRGAITEGLIREIHKRLVEGVRGNSAQPGQYRTIQNYVANSKTKEIIYTPPAPYDVPLLMAELVDWLQHEEKMPPVLLAGIAQFQLVHIHPFLDGNGRTARLLSTLCLHRSGYDFKKLFTISEYYDRNRQEYYQAIQSVRNNHMDMTSWLEYFSTALETQMHEIQLKGSQAIKLDILALKYKLFERQKQALEILLETERKFTIREYELLCPGINRRSLQRDLSHLIEIGLILQEGIKKATHYRINPSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0K1</accession>
    <name>A0A0C1K0K1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383974.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76695">
        <property type="protein sequence ID" value="KIC76695"/>
        <property type="gene ID" value="DB41_EY00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="159" mass="17825" checksum="D83A87FCD5EA8302" modified="2015-04-01" version="1">MIGFILFGMALVFTLIHKTLVKQAEPREILLSYLLFFNIGIMGLIAFSGHIFKSDQIAALIGWPPGSPFQLEVGVADLAFGVLGILSLYFRGLFWVATVVSSSIFLMGNFCIHMDSYLDHNKAPYNSGILVWFGNLVIPICLLMLLRSYLKNFHSFPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0W8</accession>
    <name>A0A0C1K0W8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GF00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76416">
        <property type="protein sequence ID" value="KIC76416"/>
        <property type="gene ID" value="DB41_GF00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.884"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="14431" checksum="01CEFF77DE38819E" modified="2015-04-01" version="1">MDQKRPIIWIGSSKKDFMEFPDGVRNEMGHALYIAQKGEKHRDAKPLKGFGGGSVIEIVQSDARGTYRTVYTVQMEKAVIILHTFQKKSKTGIKTPKQEIDLVEQRLRTAHQKYKEWLDMLKLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1H6</accession>
    <name>A0A0C1K1H6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76950">
        <property type="protein sequence ID" value="KIC76950"/>
        <property type="gene ID" value="DB41_DP00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4370" checksum="80BEF96659B93FBA" modified="2015-04-01" version="1">MAAGPQKLNKKRVGAFCSMKLANNYLKAYLEARGPSINNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1I7</accession>
    <name>A0A0C1K1I7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FK00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76586">
        <property type="protein sequence ID" value="KIC76586"/>
        <property type="gene ID" value="DB41_FK00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="81" mass="9519" checksum="03AC231B0F72D02C" modified="2015-04-01" version="1">MLTARAPFSEEQRKKGQYQNLNTFTFKDGDKRIVWLKELAFSVALITKIFKNEDGSTGILYILTNDLNYEADRICKIHYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Q6</accession>
    <name>A0A0C1K1Q6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methionine aminopeptidase</fullName>
            <ecNumber evidence="3">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">map</name>
        <name evidence="5" type="ORF">DB41_DN00160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383505.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76995">
        <property type="protein sequence ID" value="KIC76995"/>
        <property type="gene ID" value="DB41_DN00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.306"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="10"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="297" mass="32237" checksum="0FC6ABA588838C5B" modified="2015-04-01" version="1">MNEKYKQDFIQAGRMAHQVRAFGKALIKAGASYNEVITKIKEKIFSLGAIPAFPPQIALDNVAAHFLPQPDEDIIFSQEVIKLDVGICYQGAIGDCAVTVDLSGKYQALIDAVENALLSAEQSIQVGLPIKEIGRIIEEKISSYGFKPVKNLAGHGLGIYKVHMAPLIPNYCDNSTAIVKPGMTFAIEPFATDGKGLIYEAGSPTIFSFVRARPIPLSVPRSLIAKIKSFSGLPFCMHDLIEAELELPEIRRHMAELLKAGVIVGYAPLVEEGQGIVAQAENSVLVDKTGKVFITTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1R4</accession>
    <name>A0A0C1K1R4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DN00210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243778.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77000">
        <property type="protein sequence ID" value="KIC77000"/>
        <property type="gene ID" value="DB41_DN00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="179" mass="20079" checksum="85497AB00B07C5E1" modified="2015-04-01" version="1">MGIIANSLHFSGPHGYHGDERHIIKAGEKAPSSTINNEASKWCKLIFENGDREARKLVKAHYSNPEEALKDLEKIKALKICGKDLEAIPEGLSLLKNLTILDLCSNKLKTFPEGEEIKKLTKLRSLILNGNPIESLPDYVINQEMNNLRSISLYRTKIKEIPYSCKNIIASYPATVTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1W9</accession>
    <name>A0A0C1K1W9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperonin GroEL</fullName>
            <ecNumber evidence="3">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-60</fullName>
            <shortName evidence="3">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groL3</name>
        <name evidence="3" type="synonym">groEL</name>
        <name evidence="3" type="synonym">groL</name>
        <name evidence="6" type="ORF">DB41_FB00180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384042.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76676">
        <property type="protein sequence ID" value="KIC76676"/>
        <property type="gene ID" value="DB41_FB00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.630"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="533" mass="56818" checksum="6108787B8449E848" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K237</accession>
    <name>A0A0C1K237_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DF00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383406.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77080">
        <property type="protein sequence ID" value="KIC77080"/>
        <property type="gene ID" value="DB41_DF00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="185" mass="21194" checksum="E7ADAD526AEB54CD" modified="2015-04-01" version="1">MEEPILSLNSTIHSSIKKATLIKGTIYGAAGISLWLYGGIFLSPSVLATWGWVLLLLGGIFITLGLLPYRQLSYLENTPHQVKVDSLNELYFALHGRILFKVSLEKVDEIAYLDDDKHYGIGLWIALTSKDITALHYSLDLPLYLEENQKKYFCDLFLPYFSKRSYHDLEEIYKNLKKESTIINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K244</accession>
    <name>A0A0C1K244_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DC00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243760.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77085">
        <property type="protein sequence ID" value="KIC77085"/>
        <property type="gene ID" value="DB41_DC00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.215"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3b" evidence="1">
        <location>
            <begin position="54"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="1">
        <location>
            <begin position="117"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="421" mass="48045" checksum="8119D122AD71BA84" modified="2015-04-01" version="1">MNQAALYLLATFFFTQCLSQPVYSDLEKTAYSSHHLPSNLNPDSSAPAQPFTAFTGRTLKNKVRIRLQPNLEAPILRESNKGDLWIVVGERDDFYALAAPEDLKGYVFRTYVLDNTIEGNRVNVRLEPNLEAPIIAQLQTGDKVDGQISALNNKWLEIIPPASTHFYIAKEYIEKIGNADLKASLNHKRKEGVSLLESTLTQSQQEFLKPWNQINLEKINDNLSKIINNYSDFPEIQIRARELLATIQEDYLQKKIYYLENLSTHAEQLHTHNKTLSSKVALQEQRIAELEQANQPELLSNSPVASSSHIVDRMSAWLPVENQLYETWAEMHDNQPISAYYEDQWQQASTIKGVIQLYDRSVRNKPGDFVLLNPATQLPMAYLYSTQVNLQNYLGRDITLKASPRDNNDFAYPALFVLSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K291</accession>
    <name>A0A0C1K291_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">rplX</name>
        <name evidence="4" type="ORF">DB41_EI00060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383812.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76791">
        <property type="protein sequence ID" value="KIC76791"/>
        <property type="gene ID" value="DB41_EI00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="3">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="119" mass="13394" checksum="DE938F6F4BCA4B83" modified="2015-04-01" version="1">MTKVKTHKAIRKGDKVIAIAGNFKGQKGEVIARLGDKLLVQGLNLRKKHVKKSEAHPHGGIIELEKGIHISNLKVLNTEDNPVKLKAQKSDEGHKEWVYKQDDKHVVHRVVKKTKSKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2B5</accession>
    <name>A0A0C1K2B5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">murA</name>
        <name evidence="9" type="ORF">DB41_CX00060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77140">
        <property type="protein sequence ID" value="KIC77140"/>
        <property type="gene ID" value="DB41_CX00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.159"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="45"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="60"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="2-(S-cysteinyl)pyruvic acid O-phosphothioketal" evidence="7">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="515" mass="56810" checksum="42DFFA00A9A42BF9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2F4</accession>
    <name>A0A0C1K2F4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EF00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000045">
        <property type="protein sequence ID" value="KIC76846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383758.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76846">
        <property type="protein sequence ID" value="KIC76846"/>
        <property type="gene ID" value="DB41_EF00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007485">
        <property type="entry name" value="LPS_assembly_LptE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04390">
        <property type="entry name" value="LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134077" evidence="2">
        <location>
            <begin position="24"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="186" mass="21151" checksum="6DF0620FC21A2814" modified="2015-04-01" version="1">MTRCYLWIFFTPFFLMTSCGYHAGPEEVLSSYQTICIPYVKNDAKGQLTANLIKLVSTQTGLQYQNWGGDLTLLVDLLPIENENVGYHYERKNSGKLRHSIIPTETRLIAIAQVTLVDNMKGKSLWGPAKVMASIEFDHEYEKTRDGINVFSLGQLTNYDEAYEAAHSPLYDQLSQKIIDFIINSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2J0</accession>
    <name>A0A0C1K2J0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">dnaK</name>
        <name evidence="10" type="ORF">DB41_DW00030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383677.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76891">
        <property type="protein sequence ID" value="KIC76891"/>
        <property type="gene ID" value="DB41_DW00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.408"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="603"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="658" mass="71221" checksum="EDBD1BDBC2609837" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2K6</accession>
    <name>A0A0C1K2K6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">dxr</name>
        <name evidence="11" type="ORF">DB41_DT00100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383663.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76916">
        <property type="protein sequence ID" value="KIC76916"/>
        <property type="gene ID" value="DB41_DT00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.399"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="142"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="257"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="378" mass="41831" checksum="59B00805EA543F46" modified="2015-04-01" version="1">MKNLSILGSTGSIGLNTLKVARHLKDKFRIVALAAKSNVDLLEQQAREFHPELICVYDEKMAMELKRKLPEVEVVAGLEGLQAVATHGKAEMVISAMTGTKGLAPTVAAIQAGKNVGLANKESLVSGGELIMSLIKKNGVHLLPIDSEHSALFQCLNGEDPKKIDRMILTASGGPFRTWSSEQLAQISVEQALAHPTWNMGPKVTIDCSTLMNKGLEAIEAHWLFSVPIEQIEVVIHPQSLIHSMIEFTDGSIMAQMGEPNMIVPIQYAMTYPERDQGMLPRFDFTRIHEFQFYPPDFKKFPCLGLAFEAIRQGGSLPCYMNAANEVLVNRFLNKEIGWQDISNKLEKLMNAHPLSKVDTLEDVLTIDEIAREEAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2T6</accession>
    <name>A0A0C1K2T6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DM00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000029">
        <property type="protein sequence ID" value="KIC77021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77021">
        <property type="protein sequence ID" value="KIC77021"/>
        <property type="gene ID" value="DB41_DM00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4721" checksum="B40BE2B0DB1DEE3F" modified="2015-04-01" version="1">MNPKKSITKIKANTARKIRKSAKVFIKYKSLLSAFKIKIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2X4</accession>
    <name>A0A0C1K2X4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DI00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243770.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77051">
        <property type="protein sequence ID" value="KIC77051"/>
        <property type="gene ID" value="DB41_DI00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="425" mass="48295" checksum="893E9BC49151537B" modified="2015-04-01" version="1">MTPTFFDFFKSFYYSNTYVPSVDLSEQRLSRHLLENEDNKAAATAQRLISDPEVQQILSKPLVYDREKITEKNQILTRHGFNLLSDKPFLDVDTLQRIRFYSVIEHDELDGWIIKSGASRVPKDQLNIGPMNDRNEMAFFINEESILRIEMGKRIQKVAREANIDIVLPRKKLVAYANLDGVTELNRKYCVVCEKINILSVEDTVQAIKEMDAEHQREIARKISTIVQKAGFVDASFDNIRLTPAGKLAFIDTEPAGLMVAKKPGLWNKLFGPKGASVEKCARIGLFTLMHQTSKVIRGTHTSRLDARNCEPGLEVFRTEVQTHYEKATSPKLSKWKIALSVVSVGLIPLINAIIALVKTKLTKRTFEKLQAIDTLFMRQVFALTLKSPAEQKRLGKEYQEKRTPIAKQFYAYTEGVPCKVALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6K8</accession>
    <name>A0A0C1K6K8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74882">
        <property type="protein sequence ID" value="KIC74882"/>
        <property type="gene ID" value="DB41_IB00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5774" checksum="DDCE05D921C62870" modified="2015-04-01" version="1">MLYKVIKKSYCLKAESFFEQARTIGYKEAECKAVFNGEKRHGRIKERGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K811</accession>
    <name>A0A0C1K811_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HS00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385438.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000129.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75312">
        <property type="protein sequence ID" value="KIC75312"/>
        <property type="gene ID" value="DB41_HS00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UCH" evidence="2">
        <location>
            <begin position="257"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="758" mass="86983" checksum="EC2940258A8B0A5A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K868</accession>
    <name>A0A0C1K868_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HN00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75387">
        <property type="protein sequence ID" value="KIC75387"/>
        <property type="gene ID" value="DB41_HN00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="9974" checksum="440A17C63375E39F" modified="2015-04-01" version="1">MLPSKANQAASEVWQQLIVYTHRNRDYANLFKNLIKTSSLLNVKTLTTYAKKFMSQRLIGKMLEKMLRKEVDEHLYLKLTITGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K932</accession>
    <name>A0A0C1K932_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HI00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385278.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000119.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75652">
        <property type="protein sequence ID" value="KIC75652"/>
        <property type="gene ID" value="DB41_HI00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="262" mass="28514" checksum="71D8D804AB3D64FE" modified="2015-04-01" version="1">MSSINEGSKIELTEKINELASLESISPPRGGTEIESALKLFEQAAKTNQPIPLNLKALVTILSKEISSYGKQAKDIGVVTGGSSAWNAYQLIKLLMEIKKNNYFENRQLISLAPANAASQELKDDIDDQLSKAYLKAAVLSLRILKASTLLISHPLIKNGAQSTMDAGTHLLSIYSEAKIEKPLLRRNPSISTWKDTADKTLKISLSCISLVGSLYALAASCEWVEDQDPTYELVKKASLVSVATSIVYSVCQQVGLMAKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9E0</accession>
    <name>A0A0C1K9E0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rpsP</name>
        <name evidence="4" type="ORF">DB41_HE00080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385079.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75792">
        <property type="protein sequence ID" value="KIC75792"/>
        <property type="gene ID" value="DB41_HE00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1142"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="110" mass="12475" checksum="F43DF42C62EA3A1B" modified="2015-04-01" version="1">MALKIRLRQQGRHNRPFYRLVVADGRSPRDGKYVEAIGWYNPFATQVEQEFSLDAERAQHWLSQGAVLTDSAEALIKKSAPSLVRGLVDKKLALRAKYAAKRKARKKVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9M5</accession>
    <name>A0A0C1K9M5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GZ00410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384995.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75877">
        <property type="protein sequence ID" value="KIC75877"/>
        <property type="gene ID" value="DB41_GZ00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="244" mass="27403" checksum="C08CDEE9E03670FC" modified="2015-04-01" version="1">MVVDLGHLQNPDGLKQILMGMKEDQASDKLVAKAAIIASEQKAELQEQQSEEKNPLAAALRRSDRQIKAHTSSVKKAKEAKLAQKKLMPPKELEERAQEFSRRNPQFPPAGLLALTEKLKDGMSKQEILEMIQKEYPNPIEASLALEFLISVTLEDFKETLQFAQVDLNKEIIDKREQEVAQKVEKEAKKATQEATEAALKIVQGGDLNKLLDYLMSNPIEATAIYKMLDEGYGKNLKKLSLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBN8</accession>
    <name>A0A0C1KBN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FQ00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384309.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000078.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76547">
        <property type="protein sequence ID" value="KIC76547"/>
        <property type="gene ID" value="DB41_FQ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="97" mass="10870" checksum="4EE98B4FA31315B7" modified="2015-04-01" version="1">MDNNVEIDTDLIAGQLLGNHSEDAESRETGIEEIKRAYAECMNLELIISEDCNFCEIKIQQQKYYIIAKKVSQVASFAIKASLVVGPMVPKVFAIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCE0</accession>
    <name>A0A0C1KCE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EO00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76762">
        <property type="protein sequence ID" value="KIC76762"/>
        <property type="gene ID" value="DB41_EO00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="5024" checksum="E6F805DDF34FDC73" modified="2015-04-01" version="1">MYEHLKFKTVNVKTYYISLGLLILKSCLCLFIAFNYSPYAQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCQ2</accession>
    <name>A0A0C1KCQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative hexose phosphate transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">uhpC</name>
        <name evidence="7" type="ORF">DB41_ED00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000043">
        <property type="protein sequence ID" value="KIC76852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76852">
        <property type="protein sequence ID" value="KIC76852"/>
        <property type="gene ID" value="DB41_ED00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.452"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000849">
        <property type="entry name" value="Sugar_P_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002808">
        <property type="entry name" value="Hexose_phosphate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="34"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="419" mass="47140" checksum="9A92F1AAEB179FB5" modified="2015-04-01" version="1">MNWLLRLLRPAPYLPEIQDQEEVKHLYNYWRIRILYSMFIGYAFYYFTRKSFTFAMPGIIAELGFDKSQLGILASIFSITYGFSKFASGIISDRSNARYFMAFGLIITGIINILFGLSSSLFLFAIFWGLNGWFQGFGWPPCARFLTHWYSQSERGSWWSTWNVSHNVGAFLIPWIVGFCAYYFGGWRAAMYVPGIICILGGFYLINRLRDTPQSLGLPSIEKFRNDYSGNGSQPEDEQLSAREVLVEYVLKNKYIWMLAISYFFVYFVRTGINDWTALYLIETKGYNQLSANGCVSLFEVGGFFGSLAAGWASDYFFAAKRGPVNVLFAVLMFIAIAFFWFVPAGYPLVDSAAMFTIGFAIFGPQMLIGVACAELSHKKAAASSTGFAGTFAYMGAAVAGYPLGKVTQEMGWDGFFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD43</accession>
    <name>A0A0C1KD43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative chromosome-partitioning protein ParB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">parB</name>
        <name evidence="5" type="ORF">DB41_DP00140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383563.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76962">
        <property type="protein sequence ID" value="KIC76962"/>
        <property type="gene ID" value="DB41_DP00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.346"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="15"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="273" mass="31054" checksum="BA151D97F35A1820" modified="2015-04-01" version="1">MNVSQEKLSLFEELRNVPLDHIDISPFQPRRQFAEAELKELAESIKAVGLIHPPIVRPLENSLHYELVAGERRLRAAKLAGLLEIPVLVRSSSHILSAQAALIENIQRVDLNPIEISKALSSLMEEFKFSQEKLAASVGKKRSTIANYLRLLSLPNLIQDSLSKNLITMGHAKAILAVEGAEKQVYLHELILRESLSVREAEKAVQKLKQKIKQKKLSYETRDFYLEQLAEKLQYKLGTKVFIRARGRQGRISIDYFNLDDLERLLEALGVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDB8</accession>
    <name>A0A0C1KDB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DN00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77007">
        <property type="protein sequence ID" value="KIC77007"/>
        <property type="gene ID" value="DB41_DN00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="230" mass="25334" checksum="855409BF23E1432C" modified="2015-04-01" version="1">MTAEEKRAINFEHIMAILQGDSLLPSALAGLDPKKLSPEISMLDRIYRNAINNYIKTLEFATALDANNLKKLRNRHQWTWVKIAVAGAAVLGGTGALGGALAGGGIGAVPAGAITFACGLLGSSFSARKLVDTFVLREGSTHRLKWIQSIDLAEKNRLENMQVHLELSAARVLKELQELEKDEECSVDLFKTLQQHFLVNQTLFPQQSFIIEGVDIAIFLQQLKNKFTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDE4</accession>
    <name>A0A0C1KDE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DL00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77027">
        <property type="protein sequence ID" value="KIC77027"/>
        <property type="gene ID" value="DB41_DL00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.272"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="210" mass="23783" checksum="15857BE3FFF93AFA" modified="2015-04-01" version="1">MLKSNLIAYAFYHLRNSALQRTKKLKFLINDNINIDKKCNNMIAFILIINFVEEVIMYFTSVPAFGFETFACNAETCYKEIAQKTSQKTLNLQMAKLNAVIPDLQETPYFDDPEHQKIRDESITNAAKGAWKTANIVKALGYIPLIGTLIGVGRISKAMKATKDELPNKYNHIVRGCVELLSLGFLLLIPDLILTGYRAYNVRNRNVITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDG9</accession>
    <name>A0A0C1KDG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DI00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77052">
        <property type="protein sequence ID" value="KIC77052"/>
        <property type="gene ID" value="DB41_DI00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7810" checksum="377BBA5E474F38EC" modified="2015-04-01" version="1">MNSLAKRADMVMNLAARAREIFERSKVDEKRQLLNFVFKNLKLDGKNLSIQTCESFSTLVGYKRCPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDL1</accession>
    <name>A0A0C1KDL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein YlaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ylaK</name>
        <name evidence="4" type="ORF">DB41_DC00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383377.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77087">
        <property type="protein sequence ID" value="KIC77087"/>
        <property type="gene ID" value="DB41_DC00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.217"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="3">
        <location>
            <begin position="4"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC77087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="432" mass="48490" checksum="CA6F3938D1908D61" modified="2015-04-01" version="1">MLSKTFVLDTNVLLHDPEAIIKFPGQNVIIPVTVLEELDKMKRLPSDLGRNSRAVFRYLSNLNTIGAGNLHAGVTLDNQAVIRIQVEFKTDYSYNFALSNNDNKIILAAFFLKEKGENVVFVSKDFAARIKAEAIGLETEDYENLKYSYASMYKGLRRIEMPKHAIDVFYKDGAIQVEAEDLHPNEYCIFSSPEHSSGVGKYNAKRGIVEPLIKANNLWGIKPLNVEQRCAIDALLRDEIKLVSLIGQAGTGKTLLALACGLRKVFDEGTYTRILVSRPVIPLGRDIGYLPGTKEEKLLNWMQPIYDNLEYLCDSAGSEPSETLRWVMESKKIEMEAVTYIRGRSLPKMYIIIDEAQNLTPHEVKTIVSRAGENTKVILTGDPTQIDNPYLDKDSNGLSYVVGRFSNQQVYGHVFMEKTERSELAALAAEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDR7</accession>
    <name>A0A0C1KDR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DA00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000017">
        <property type="protein sequence ID" value="KIC77117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243757.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77117">
        <property type="protein sequence ID" value="KIC77117"/>
        <property type="gene ID" value="DB41_DA00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="391" mass="44252" checksum="297A1C7615C0E5F0" modified="2015-04-01" version="1">MHPISPASIESLPNELLLPILEACVVPSLFSVCKRWHHLLASEVMPSLYKQIGKVHVPQGNVKEQALIVDRIYKLEEKLSEAAKVNAIFRQIFTLASYLSPLKSKENEELSEIAKVNVIFRQIFNLASSFFSLKSKGQIEEKKSFTLANYSSYLLNINRLLLWKKLPGGEEYLSRGEIKHLPLKKKGELLREWIEENCKNIKALDLSEAGLTYLPQEIGRLSQLQTLYLRENQLTSLPVEIGQLSKLRKLNLSENQLTSLPVEIGQLSQLRKLYLSENQLTSLPVEIGQLSQLRKLYLSENQLTSLPVEIGQLSKLQTLELDQNQLTALPAEIRQLSKLTRLELSHNQLTALHAELGQLSQLEVLGLKSKPAHRSACRTRAAISARSSWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE47</accession>
    <name>A0A0C1KE47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243736.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77247">
        <property type="protein sequence ID" value="KIC77247"/>
        <property type="gene ID" value="DB41_CO00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010261">
        <property type="entry name" value="Tir_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05932">
        <property type="entry name" value="CesT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="18064" checksum="4373F265CDB6350E" modified="2015-04-01" version="1">MELEDLLLEYGRSKQLGRLQLDSSGVCTLLMNGHYLLTFEKSLDQEGFYLYSSVGDLPLEKEGEASLMALKGNLFGRETGRASLGYVEQTRSLVLFEYFDKNELNYLQFIQRFNQFVKYLFYWITKLKASASQDSDKKAAVEPRPTFHHSKKIFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1K5</accession>
    <name>A0A0C1H1K5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">mreB</name>
        <name evidence="3" type="ORF">DB41_AV00190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386913.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71579">
        <property type="protein sequence ID" value="KIC71579"/>
        <property type="gene ID" value="DB41_AV00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2255"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="41"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="185"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="233"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="314"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="363" mass="38974" checksum="5CD486B7D9C9FDEA" modified="2015-04-01" version="1">MSKKNQLGIKDNFSKMARSAFGQLTKFRGVFSNDIGIDLGTANTLVFVRGKGIVLAEPSVVAVDSTTNEVLAVGQKAKAMLGKTPRKIHAVRPMKDGVIADFEIAEGMLKALIKRVTPSRSLFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVILIEEPMAAAIGVDLPVHEASANMIIDIGGGTTEIAIISLGGIVESRSLRIAGDEFDECIVNYMRRTYNLMIGPRTAEEIKMTIGSAYPLGGNELEMEVRGRDQVAGLPVTKRINSVEIRECLAEPIQQIIESVKLTLEKCPPELAADLVERGMVLAGGGALIKGIDKALIKETGLPVIIAQNPLLAVCLGTGKALEYLDKFKRRKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H389</accession>
    <name>A0A0C1H389_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RecC_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_AA00250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386574.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72044">
        <property type="protein sequence ID" value="KIC72044"/>
        <property type="gene ID" value="DB41_AA00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2097"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009338">
        <property type="term" value="C:exodeoxyribonuclease V complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01486">
        <property type="entry name" value="RecC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006697">
        <property type="entry name" value="RecC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041500">
        <property type="entry name" value="RecC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17946">
        <property type="entry name" value="RecC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000980">
        <property type="entry name" value="RecC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecC_C" evidence="4">
        <location>
            <begin position="841"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1140" mass="133130" checksum="F4E717CCF4335784" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4P8</accession>
    <name>A0A0C1H4P8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72499">
        <property type="protein sequence ID" value="KIC72499"/>
        <property type="gene ID" value="DB41_KK00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4609" checksum="DDA904EB6FCD8D63" modified="2015-04-01" version="1">MDQHQEGLDNSLSNVNRKKHLKIIRKNIGEIVPPVDTNVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6S4</accession>
    <name>A0A0C1H6S4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JQ00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73154">
        <property type="protein sequence ID" value="KIC73154"/>
        <property type="gene ID" value="DB41_JQ00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="23648" checksum="74F7E71A6C2FE2C4" modified="2015-04-01" version="1">MQVPFISFFVWLSKVLSLRHYLRRSSRPHSRKHVLLLEVLIAFALTGLCIFPLIYPQVVIAKSQREFIKKIELDRVVTLLFAQIYQDLFTNKISWADIEEKKSFALSSEDLKALNQQQNLPFKGSYHFEPIIHKPKGNTSQQESTAYLIHLIFKFTSNLTPKNKINAQQALVYKYKIFILRDLRGSKLAPQDHEQPFPLYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8H3</accession>
    <name>A0A0C1H8H3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CD00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000249">
        <property type="protein sequence ID" value="KIC71173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71173">
        <property type="protein sequence ID" value="KIC71173"/>
        <property type="gene ID" value="DB41_CD00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2316"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="184" mass="20896" checksum="55B56F6952CBE506" modified="2015-04-01" version="1" fragment="single">AEIGQLPQLQELNLNQNQLTSLPAEISQLSQLQELYLNQNQLTSLPAEIGRLSRLQYLFLNQNQLTSLPVEIGRLPRLQYLFLNQNQLTSLPAEIGRLSKLQLLGLSQNQLTALPAEIGQLSELQYLYLSQNQLTSLPEEIGQLSQLTKLKLAENPLKDIVEKNKAAFSIVEWLKYFSNWGELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9N6</accession>
    <name>A0A0C1H9N6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dagA_2</name>
        <name evidence="9" type="ORF">DB41_AV00230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244125.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71583">
        <property type="protein sequence ID" value="KIC71583"/>
        <property type="gene ID" value="DB41_AV00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2260"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="447" mass="48738" checksum="353B88FB592CC9BB" modified="2015-04-01" version="1">MDLYIMPSLERTNQIFTLCVVFPFIILLGLYFTIKLRGFQIARLKNSFSYLLKQQQNAQGNISYFEAISTVLAGNFGTGNISGMAIALSTGGPGALIWMWIIAFFGSAIQYSSCILGAKYRQKDEGGEYVSGPMYYLSKGLGLDSLAKIFCIFTIFAALAVGNFAQINSMTLPIQKMGFSPLLCGFIFAFFIGLVLLGGIQRIARFASIIVPLKAFLYLTFTLIILYLNREKVLPALQLMFTSAFNFQAAAGGIIGSSTLKAITTGFNRAIFATDAGTGIVPILQASARTEHPVIDGLVSLVAPCMVLIVCTMTGLVLLVTGAWQHGDLQSTNMVTYAFRIGLGHQIGEYVVIIALIMFGFTTILAWAYCATQAITYLGGHRFARPFTYLYILLIPLGTLIQINLVWGLADLCITCMLIVNLIGITGLAHEVIIDSRAYFKGDKLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9X7</accession>
    <name>A0A0C1H9X7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AT00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000216">
        <property type="protein sequence ID" value="KIC71638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71638">
        <property type="protein sequence ID" value="KIC71638"/>
        <property type="gene ID" value="DB41_AT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="110" mass="13438" checksum="F69063F10170705E" modified="2015-04-01" version="1">MAKIRNCFTRLLLFLRLLPIKIKPRRTDIPWRWRECDSPWYTFDYTDGYYKVFYYYTRKQYEIAYREPLGWSGGHKHLNGLDDNYWSGKGYKYSWPESLGIGLEKINDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAE1</accession>
    <name>A0A0C1HAE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AI00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71803">
        <property type="protein sequence ID" value="KIC71803"/>
        <property type="gene ID" value="DB41_AI00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6471" checksum="64B2ACF84EA07A51" modified="2015-04-01" version="1">MSMHALCKKMVYLEQQIEQIKIMAEELNTALEEQAPIREVIKNVQTRYEEEYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB54</accession>
    <name>A0A0C1HB54_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">thrS_2</name>
        <name evidence="9" type="synonym">thrS</name>
        <name evidence="12" type="ORF">DB41_AA00040</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72023">
        <property type="protein sequence ID" value="KIC72023"/>
        <property type="gene ID" value="DB41_AA00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2076"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="11">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="284"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Catalytic" evidence="9">
        <location>
            <begin position="257"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC72023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="665" mass="76850" checksum="C1D2444FD42F41A3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD67</accession>
    <name>A0A0C1HD67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KD00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244039.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72708">
        <property type="protein sequence ID" value="KIC72708"/>
        <property type="gene ID" value="DB41_KD00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="114" mass="13145" checksum="CCDF46C954F0CD32" modified="2015-04-01" version="1">MNFIIPSLFLGFVVDDAFARALEKNTPEYLHFFLQPGSGYLEEVTYQEEHYIGKFVSNEQNVGQLELLEAHIFSLLKKLAPDYNYTRSNLVLFALPQKEVTPAVISYKNKKRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDA3</accession>
    <name>A0A0C1HDA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HM00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000123">
        <property type="protein sequence ID" value="KIC75389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75389">
        <property type="protein sequence ID" value="KIC75389"/>
        <property type="gene ID" value="DB41_HM00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="102" mass="11267" checksum="22923A17342AE535" modified="2015-04-01" version="1" fragment="single">FNFLNHLIIVLDVMGIFVASMGSVIITRYLIEQVKKLPVTSNDYPCHFLAWMLGLAMGFSSLNGVSLTSIPVLDATIGSSLGTFFVLIQRKYSEKANIAKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE74</accession>
    <name>A0A0C1HE74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative 2Fe-2S ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cbiW</name>
        <name evidence="1" type="ORF">DB41_HH00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385215.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75724">
        <property type="protein sequence ID" value="KIC75724"/>
        <property type="gene ID" value="DB41_HH00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1214"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="14180" checksum="E6C2DCD9420BB38C" modified="2015-04-01" version="1">MQQNLNERLIKCGVDTLKRHIFLCSDQANPRCSSSDTAYASWQYLKQRLQELNLTGAGGIYRTKVSCLRICQKGPVAVIYPDGIWYHSCTPEVLEIILQQHLIGGKPVKEYILYDHSKIAYSSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HES4</accession>
    <name>A0A0C1HES4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rimO</name>
        <name evidence="11" type="ORF">DB41_GW00110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75939">
        <property type="protein sequence ID" value="KIC75939"/>
        <property type="gene ID" value="DB41_GW00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1053"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="57"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="192"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="427"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="496" mass="56010" checksum="F76A79CEE7E8BE51" modified="2015-04-01" version="1">MLPMIPKDKKPLALKSCCSDTAACCATSSSSDTLLANDKIDNLALQEGTFHFDYDGNKIHFISLGCPRNLVDSEVMLGILLKAGYEVTQELSQADYLVINTCGFLEASRKESMDTVKHALQQRKKTAKLVVTGCMVQTHHEEMEKQFPGIDYLLGSGDVQGILQAVQSTQKGKLVSNGRSFLENGEIPRQLSTPKHYAYLKIAEGCRKRCAYCVIPTIKGPLKSKSKEQILKEFNYLLNEGVHEIILIAQDLGDYGKDMGSRNQAALIDLLQSMLAIDKKFWLRLLYLYPDEITDELIALIKSDARICPYLDMPIQHINNEVLKSMHRATSREDVIKTITKLRHEIPHIVIRTSLIVGFPGETADQFEELAQFIQDYPLDNIGIFKYSREPGSYSFNLPNQIEEEVKEKRYRKLMKIQQKVLKKANSKYVGKKLMVIVEGYHPETNLLMVGRFYGQCPEIDGQIIINDSRKVKAFGELYLVEITEAAGYDLIGKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEX8</accession>
    <name>A0A0C1HEX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Na(+)-translocating NADH-quinone reductase subunit A</fullName>
            <shortName evidence="2">Na(+)-NQR subunit A</shortName>
            <shortName evidence="2">Na(+)-translocating NQR subunit A</shortName>
            <ecNumber evidence="2">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NQR complex subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NQR-1 subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">nqrA</name>
        <name evidence="4" type="ORF">DB41_JM00110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NqrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386170.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73258">
        <property type="protein sequence ID" value="KIC73258"/>
        <property type="gene ID" value="DB41_JM00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1788"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00425">
        <property type="entry name" value="NqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008703">
        <property type="entry name" value="NqrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022615">
        <property type="entry name" value="NqrA_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37839">
        <property type="entry name" value="PTHR37839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05896">
        <property type="entry name" value="NQRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11973">
        <property type="entry name" value="NQRA_SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01936">
        <property type="entry name" value="nqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0915">Sodium</keyword>
    <keyword evidence="2" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2" id="KW-0813">Transport</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NQRA_SLBB" evidence="3">
        <location>
            <begin position="273"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="463" mass="51311" checksum="BE683388C82FE2B8" modified="2015-04-01" version="1">MAYIKITRGLDIPLSGKPNEHAHSLSSASQVISLDAPSTVSLDLKPFADLKFKLLIKQDEAVKIGQPLVEDKGCPGRMFVALASGVIKEIRRGYKRSLQEIIITVSEDEPFAERPVKPLEAMSRENLIELMKEKGFFSSIRVRPFNNLANPHKAPRSIFVKAIESAPYNPPAEMQVQGYKDEFQLGLNALAKLTTGTVHLIYRAGSTCKAFIEAQNVQQHTAEGPHPIGNVSVHIQALDPIKRADDIVWVVNAQQVVALGYFLAHGRYHIERIISIAGPGVLPDRTGYFKVQTGYPIASLLAGRLQPGCQRLISGDPLTGRKVEETGFLGSEDYTCCVFPENNSREFLHFFRLGINKYSFSKGYLSGHLARFKKDYSFTTNQHGEQRAFIDSTLYDQVQPLAIPTMLLVKAVMAEDYELAESLGLLEVCGEDFALPSFVDPSKIEMGEIIDQGLKRYASEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH31</accession>
    <name>A0A0C1HH31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384155.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76594">
        <property type="protein sequence ID" value="KIC76594"/>
        <property type="gene ID" value="DB41_FI00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="186" mass="21600" checksum="08AFB75BB219D0EE" modified="2015-04-01" version="1">MSVDINVNFNNGRCFFNGFNKINDINPKTHRAGVNYYRFSIIGCILEKLGFSTKINCFVNGKPTVIFINTKSFLKWRERHSKDEYIERSQKVLNFGKDFEGSIKYIINSYNILSYEEVIAKAEKEFFNDEDKISKIELVKETLDSLDYKHSYAMKERPEIITTLRDPLFLVKFLGALPGIKLSGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHD1</accession>
    <name>A0A0C1HHD1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EY00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383997.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000061.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76714">
        <property type="protein sequence ID" value="KIC76714"/>
        <property type="gene ID" value="DB41_EY00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="663" mass="77058" checksum="46D9CFFB133F8725" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHG0</accession>
    <name>A0A0C1HHG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsA</name>
        <name evidence="6" type="ORF">DB41_EO00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383894.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76754">
        <property type="protein sequence ID" value="KIC76754"/>
        <property type="gene ID" value="DB41_EO00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.539"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000110">
        <property type="entry name" value="Ribosomal_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00717">
        <property type="entry name" value="rpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="50"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="131"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="217"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="302"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="389"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="476"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="560"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="580" mass="64998" checksum="291317155906169A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHI5</accession>
    <name>A0A0C1HHI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glyA</name>
        <name evidence="10" type="ORF">DB41_EJ00040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383849.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76774">
        <property type="protein sequence ID" value="KIC76774"/>
        <property type="gene ID" value="DB41_EJ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.519"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="31"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="165"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="178"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="494" mass="54313" checksum="4948F4D59F95025D" modified="2015-04-01" version="1">MTLLDNYFAKSANKERNKATIAYLAALDYIENTAPQISASILQELKDQRSYLKLIASENFSSLAVQLAMGNLLTDKYAEGFAHHRFYAGCENVDTVEDIATKELKSIFGCEEAYVQPHSGADANLVAFWSILVQRVQNPAIEKLGKKNLDELTPDEYENIRQLMLNQKVMGMSLNSGGHLTHGYRHNISSKMMKAVLYDVDPSTELLDYSQLANMAKQEKPTILLAGYSAYPRKLNFAKMREIADSVGAVLMVDMAHFAGLVAGKVFTGEFNPIPYAHIVTSTTHKTLRGPRGGIILCTKEYIDIVNKGCPLVLGGPLPHVIAAKAIAFKEANSKAFCDYAQKIVDNTQALAAQFRKRGIRLVTGGTENHLLILDLTHYGLTGRHAETALRQAMLTVNRNAIPFDKNGPWYTSGVRMGAAAVTTLGLGVEEMAEIADISADILTHTTPIINNKTGQPSKAQAIVEPVILEKSRSRVAELLKRYPLYPEIIVNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHY6</accession>
    <name>A0A0C1HHY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DQ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76939">
        <property type="protein sequence ID" value="KIC76939"/>
        <property type="gene ID" value="DB41_DQ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5236" checksum="18656EE548F67C11" modified="2015-04-01" version="1">MEYTPHIAKVSKECGYRGQNIKGHLKILLAKEKLFTGLGRLHQKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHZ4</accession>
    <name>A0A0C1HHZ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DQ00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76944">
        <property type="protein sequence ID" value="KIC76944"/>
        <property type="gene ID" value="DB41_DQ00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="62"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="267" mass="30070" checksum="2B1ADE1859F6F0CA" modified="2015-04-01" version="1">MESTSFLAYKNLIRIFVILLLGTLLLIGIRAGCFFSKHLSSSQSIVIARHINWNDFDFTGKELNVQAFAEELVLAAGKEANLSIQFVPANPNTLLEDLRAGNYDAVFTFMVPNSLNRQTYIFSHPLYELGSVLVVDEKSDAHRLEDMDGKIVGIIAGTSSIYDVSRYPSIILVTYESMNAALENLKNDKIDGVIMDIWHAQMMIHSFYDNKLKIATGPLSHQGLRLVSLGRPKSEEFIKFFNEGLARVKEKGLYKQLIQKWGLYDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIM7</accession>
    <name>A0A0C1HIM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DB00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77099">
        <property type="protein sequence ID" value="KIC77099"/>
        <property type="gene ID" value="DB41_DB00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5028" checksum="CDD7CAFE915CDEB8" modified="2015-04-01" version="1">MLSSKRATQRHFFKASAIAKNLLNIQADEYKNQVYEKIAVNSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ53</accession>
    <name>A0A0C1HJ53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">proA</name>
        <name evidence="9" type="ORF">DB41_IJ00240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74553">
        <property type="protein sequence ID" value="KIC74553"/>
        <property type="gene ID" value="DB41_IJ00240"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="4"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="419" mass="46719" checksum="AFA5C43917A7FE7C" modified="2015-04-01" version="1">MNRTMSDLDKKASKAKNAFLILSNVSESQKNLALSEISKALSAYLEEIKQANPQDLSPSGEDKKKLIELGCLDRVIEYISDIRRMPDLNGEIFDDQTLSNGLRLAKYRVPIGVLGYVLDINPATLIRVAALTIKSGNPLIIWAGKEIKNTCYFLVKIIQMGLEAADLPIESVQLLHSHDEEQLKDFVQCKKSVDLVLLAGSASLTTFCQKNSLIPLIYENKSVCHLYIDQLINSEKALEVIHNAKMQEAETPYSLSTLLVHEALADSFLPFLFKTLLDKGISLRLDNRCWELLVSCCLNLGNAQLAVLQDWDTAWHSNVLNIKLVKGMEEAIEHIHLHGSGSCDGILSDHPVHAMQFSSLVSSEVIMINSSLRFLDEASRGGEPETLINLHKLRIPGSLVLKELMSYKRLVQGNYHVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJ60</accession>
    <name>A0A0C1HJ60_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AraC_E_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IJ00290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385945.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74558">
        <property type="protein sequence ID" value="KIC74558"/>
        <property type="gene ID" value="DB41_IJ00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029441">
        <property type="entry name" value="Cass2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14526">
        <property type="entry name" value="Cass2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="171" mass="19621" checksum="2854697B8583BCD1" modified="2015-04-01" version="1">MRKTIIQLSEIKLVGITSRTNNSWEKDPSSAKISPTIQRYFHGAYSEKILYRAKPGTTYCVYTDYESDFNGDYTYFIGEEVSKFDVMAEGLSALVIPAQNYVKFISNPGTLPSLCINMWQKIWSMSAPELGGEREYLADFEIYDERASDHQNAILDIYIGIKSEKQRPHYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK86</accession>
    <name>A0A0C1HK86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_IB00410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tonsoku family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243972.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74908">
        <property type="protein sequence ID" value="KIC74908"/>
        <property type="gene ID" value="DB41_IB00410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1474"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="196"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="631" mass="70328" checksum="CAA054E092BF9521" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HND6</accession>
    <name>A0A0C1HND6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HB00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000112">
        <property type="protein sequence ID" value="KIC75833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75833">
        <property type="protein sequence ID" value="KIC75833"/>
        <property type="gene ID" value="DB41_HB00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="9492" checksum="A98DD9A9322C5D0C" modified="2015-04-01" version="1">MGVGKRLESLKNNRSRMKRELHARVCGSLRGRFPWATRCLEDAHLTYPDRIEKLIFALSIAFCWAYKLGNIAANVFPISIKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNF0</accession>
    <name>A0A0C1HNF0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_C39_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75843">
        <property type="protein sequence ID" value="KIC75843"/>
        <property type="gene ID" value="DB41_GZ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C39_2" evidence="1">
        <location>
            <begin position="162"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="328" mass="37066" checksum="62F1336728E33114" modified="2015-04-01" version="1">MITMLLLFIGSLLFLPLQASQTLHKEIDQKELHGKSIEWEQTGLTPFNELIVSWDAQRPKHGYYLIKVSLLTDNKWSPWLNYAYWGSSHQYTFNCHPRNSSCKTYQDVAGPLGRKKATGFKIRVDCSESSLLKNIRTLHASFTNIQEHKVSFDLAPHYSINLNVKGLSQVTLPDERHMRLCSPTSTTAVINYLSPGIHLSALTFADHVKDSAFDIYGNWLLNTAEASNLLGPSWHSYVARLNNFDQIMESLSRGFPVVVSIKGPLTGSASPYSSGHLIVVKGYEAEKQQVLCMDPAFPTDQSTLVSYSLKDFLVAWNRRKGIAYLFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNM9</accession>
    <name>A0A0C1HNM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GX00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000109">
        <property type="protein sequence ID" value="KIC75903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75903">
        <property type="protein sequence ID" value="KIC75903"/>
        <property type="gene ID" value="DB41_GX00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1802" mass="201596" checksum="7FCAA3D31C976CD3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNT6</accession>
    <name>A0A0C1HNT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GU00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384876.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75958">
        <property type="protein sequence ID" value="KIC75958"/>
        <property type="gene ID" value="DB41_GU00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="80" mass="8596" checksum="A032A9A5B8CD94B1" modified="2015-04-01" version="1">MLKSICFFLGIAGLSLTPILGAGLKISNRLHAIHFGPGPTGDQGQEVEEEKRQNLYAINFGPGPDGDQEVEEDKNADETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNU2</accession>
    <name>A0A0C1HNU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GU00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75963">
        <property type="protein sequence ID" value="KIC75963"/>
        <property type="gene ID" value="DB41_GU00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6645" checksum="E00A588C82627490" modified="2015-04-01" version="1">MLLANRAIFSYLLISFYGYLSDGSEILNLFIFIFPLWARSLFILACFVDISPLPFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPG5</accession>
    <name>A0A0C1HPG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GM00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000098">
        <property type="protein sequence ID" value="KIC76128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384772.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000098.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76128">
        <property type="protein sequence ID" value="KIC76128"/>
        <property type="gene ID" value="DB41_GM00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="885" mass="101933" checksum="1B701BEAAAC3AF01" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQL3</accession>
    <name>A0A0C1HQL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GB00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000087">
        <property type="protein sequence ID" value="KIC76473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243868.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000087.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76473">
        <property type="protein sequence ID" value="KIC76473"/>
        <property type="gene ID" value="DB41_GB00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.825"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="48396" checksum="D984C0ED9D619874" modified="2015-04-01" version="1">MNFSFSITIEHLPSKILVPILKACASPSLSSVCTRWRHLLVTEVMPSLYKQIGKMHFPQGNITGQAHVLDKLYKLESGLSEVAKVNVIFKQTFTLANSLSPIELKGKKVNIIFKQILTVTSSFFALEFKDKPTEKRYLTLANYSSYLININHHLMWKEIPGGKEYLNQEEIKHLPLAKKRKLFRDWIGRYGKDITRLNLKGAGLTFLPPEIGQLSQLRYLYLDGNQLTTLPVEIGQLSQLRYLYLDGNQLTALPAEIGQLSQLQWLYLNSNRLTSLQAEIRQLPQLQTLGLENNQLTAFPLEIGQFSQLQYLNLNNNQLTFLPVEIGQLSQLQYLNLNNNQLITLPAKIGQLSQLQMLNLNNNQLACLPAEVGQLFQLKWLDLSNNQLTTLPAEIGQLPERLNLNLKENPLRSISDEIKQHFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR47</accession>
    <name>A0A0C1HR47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76593">
        <property type="protein sequence ID" value="KIC76593"/>
        <property type="gene ID" value="DB41_FI00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="188" mass="22653" checksum="60100867BC220A96" modified="2015-04-01" version="1">MCNRDAYLGPFLLNLLPFSPFSEMRKKMIKRADEEVRIRIDNIRNIRRIEKDLDNKVNYLEAYYLNAFEKNGKFSQENKTLEYKISCAQNLSAYYCLIYAQEDVLSAKHSYDNRFEEVNRLMEIENSFESKFSPKIILRLAKYEMERKTTFSEKQRELILTYMHKNYKKAKEMRMEKIITEACSKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR68</accession>
    <name>A0A0C1HR68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">xerD</name>
        <name evidence="10" type="synonym">xerC</name>
        <name evidence="14" type="ORF">DB41_FI00230</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243843.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76613">
        <property type="protein sequence ID" value="KIC76613"/>
        <property type="gene ID" value="DB41_FI00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.696"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0229">DNA integration</keyword>
    <keyword evidence="8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="13">
        <location>
            <begin position="7"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="12">
        <location>
            <begin position="114"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="300" mass="34183" checksum="110888A55ABA3DCC" modified="2015-04-01" version="1">MQKSSFSLLDTIFEDFLSYIGSEKGLAVNTIEAYQRDIAAFFAFIRKKGLTAIQQVDEEHLMDFVASLQAAGYASSSIVRNLIAIKVLCRFLKREGNLPTNFSLYFATPKAWQLIPTVLSYEEIERLLEAPDIETLQGSRDKAMLEIMYACGLRVSEVCSLKIYDVDDEYVRVMGKGKKERLVPIGFKAIQAVDHYLHHYRSLAESEKSKELFVSSRGKPIDRVSVWRMIKTYMKKAGILKNISPHSLRHSFATHLLENGADLRVIQEMLGHASISSTDRYTQISKSRLQKSFDEFHPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRI9</accession>
    <name>A0A0C1HRI9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EO00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76748">
        <property type="protein sequence ID" value="KIC76748"/>
        <property type="gene ID" value="DB41_EO00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="422"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="488" mass="55951" checksum="DC16F6202CCCDD3C" modified="2015-04-01" version="1" fragment="single">MNLETLRIRPFIFPAFEQQQEQSNPFIRDTSVYGEIALIIFKKLGLLDSCQARLVCKDWKQLIKQTNEWQEPSSKGLKDNLPRHHSQTTAKKKLLTSSLRRWSPSQIAKSLWYNPATIISNSVEIKVNAVATYLHKEGFELKGVAGDGDCFFSAFLGSYEGLSRKIPVLDEQNDKIFYLRHVLSDIYRHVNSKRAKEIREKGSWVSGLGEGDLLAQALSIPIRLVTVNEDSLGCGINDMLISSKVGLTSKKDRSQEWETIPQEERRQDYIFIVDLGGHFIYAQKPLKQDKTLLLKSKISSNILFSNSLSTNELENTLKTLESQELLSDEKIKELEQTYTQALQIAVREKDPIQESFCIEELGDIYLGKQTSETLLQAAGLYNYALRLVPQERLKVLRTRLSQVQNLLVKQCKGKPFDPLVIVKQFERNRSELKKFREEIEKKIQTLLENPSSQEVRELYGEIAQHIKIFFGQLVIQAVHQLDTAPCEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS00</accession>
    <name>A0A0C1HS00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_DY00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000039">
        <property type="protein sequence ID" value="KIC76888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76888">
        <property type="protein sequence ID" value="KIC76888"/>
        <property type="gene ID" value="DB41_DY00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="182"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="308"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="383" mass="42886" checksum="3AC0FC94F1BBA60F" modified="2015-04-01" version="1" fragment="single">MNFKLFGENHPKVAIDYSNLGRIYKKQGNLDKAAEYSNKALAIDLKLFGENHAEVATDYNNLGAIYKEQGNLDKAAEYAKKVLDINLKLFGENHSTVAKNYSNLGQIYYQQGNLDKAKDYTSKALAINLELFGENHPNVAIYYSNLGEIYQDQGKLGEAAEYSNRALAIKLKLFGDNHPAVAIRYNNLGQIYQGQGNLDKAAENTEKALAINIKLFGETHFNVATNYNNLGLIYQEQGNLNKAVEYSAKALAINLKLFGENHPEVAICYDNLRKIYQDQGNLDKAKDYTHNALAINLKLFGENHPEVAICYDNLGQIYQDQGNLDKAKDYTHNALAINLKLFGENHPEVAICYNNLGQIYQEQGNLDKALEYANKALAINLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS96</accession>
    <name>A0A0C1HS96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DP00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76963">
        <property type="protein sequence ID" value="KIC76963"/>
        <property type="gene ID" value="DB41_DP00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="11020" checksum="59979127E0E4A77C" modified="2015-04-01" version="1">MKKTYSRDLKIKFSKKLYPLDNAYAKQIDSQTQFKKLCLPYEKVLYHLDRRLIYPACSLACLVNILKLSVFILSVSFHKKLKKNQLPAEVKAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT28</accession>
    <name>A0A0C1HT28_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">dut</name>
        <name evidence="6" type="ORF">DB41_CP00080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383167.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77223">
        <property type="protein sequence ID" value="KIC77223"/>
        <property type="gene ID" value="DB41_CP00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.83"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="69"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="86"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="150" mass="15822" checksum="EE735D0BD9ACDB1D" modified="2015-04-01" version="1">MNPALSVEVLVLSPDVSCLPQYASLGAAGADVRAYLKEPLVLAAGESCLIPTGLRMAIPQGYEIQVRPRSGLALKNQVTVLNTPGTIDADYRGEIGIILINHGKQDFIVTPGMRIAQFVLAPVTVGNFILSEKLTDTARGDGGFGHTGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT99</accession>
    <name>A0A0C1HT99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tgt</name>
        <name evidence="5" type="ORF">DB41_CJ00080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000001">
        <property type="protein sequence ID" value="KIC77298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77298">
        <property type="protein sequence ID" value="KIC77298"/>
        <property type="gene ID" value="DB41_CJ00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.8"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TGT" evidence="4">
        <location>
            <begin position="5"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="267" mass="30259" checksum="36B84877F2111884" modified="2015-04-01" version="1">MSALNKVTDKGVHFQSHIDGSRHFLGPDESMFIQKTIGSDIVMAFDECTPYPCEKKIVEKSLERTHRWAERCRNYDLQPHQNLFGIVQGGVHADLRQQSAQFLANLDFQGYAIGGLSVGEPASVMYEVLDHTVPFMPVEKPRYLMGVGTPRNLVESVMRGVDMFDCVMPTRNARNGTAFTWTGKVQIKAARYAEDFSPLDPSTPSYTSQFSKAYLRHLLNVDEMTGLTLVTLQNLAFYLDFMQKLREAIKNDTLADFYQKVCALYPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKC9</accession>
    <name>A0A0C1JKC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ribosomal RNA small subunit methyltransferase B</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsmB1</name>
        <name evidence="7" type="ORF">DB41_AM00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386742.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000210.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71745">
        <property type="protein sequence ID" value="KIC71745"/>
        <property type="gene ID" value="DB41_AM00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="6">
        <location>
            <begin position="151"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC71745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="413" mass="46603" checksum="8E0FCE404C415670" modified="2015-04-01" version="1">MINSREAAFFALLHSLKGESFISEYLGEWFKKEQPSSQDYQLAHQIAYGSAQMALALDYLALQLSEKKKMRLKLKEKALLRTALYQFYFLDKLPHYAIVDESIKIAKKHFHSYFVAYLNAILRKFSLLSLTLPQGMDLPSLSIRYSFPLYFIKNLSKHYGLQATIKILEASNKPALTMARLRNIVEIPAEWNTVIEEPVKVITVLASEVKKVASSADYYIQNVTPASLIGSLSQGINKAPTSILDICASPGGKTLALHDFFPQAALYANDVSLHKIQKLKDNFAKYGVQAQVSCSEGEKLELDKKFDLIVLDVPCSNSGVLSKRPEARWRLNEDQAKQLKIIQFNLLKHAVHLLENEGEIWYMTCSILPEENEEIVAIACQELDLIKKNLISILPNAEGWDGGFACCLVKKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKJ6</accession>
    <name>A0A0C1JKJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_3</name>
        <name evidence="3" type="ORF">DB41_AF00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244096.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000206.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71815">
        <property type="protein sequence ID" value="KIC71815"/>
        <property type="gene ID" value="DB41_AF00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2144"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="587" mass="65838" checksum="F2434B726FB3692E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKT6</accession>
    <name>A0A0C1JKT6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CC00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000248">
        <property type="protein sequence ID" value="KIC71176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039387073.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000248.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71176">
        <property type="protein sequence ID" value="KIC71176"/>
        <property type="gene ID" value="DB41_CC00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="3"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="36840" checksum="ED3E8B0103C7D8BE" modified="2015-04-01" version="1">MRIAIIGTGLSGLATGWFLLKKFSCKQRPSITFFDHLGVGGGASGVAAGLLHPYVGATAKLNRYGLEGFEATEKLLNLASEKMGMPVASYNGFLRVALSLQQKKDFQRSAFKYDDLLWLEAKEAKQKISGLSFHPALFIKKCMAVDCSLYLEGLWKACNEKGAVLERQEIETLDELKAFDHIVVATGAFVNRLLTPQKLPVTEVKGQVIDIVWPNSLEPLPCPLSSQAYLIMNKGKNSCTLGATYERGFQSAQANLKMASGEIMPKALALLPALEGATVLNCRAGVRASTPGHMPIIQKIGVNVWVITGMGSKGLLYHALYAEKLVDMMKERQACHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM94</accession>
    <name>A0A0C1JM94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AS00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386804.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71661">
        <property type="protein sequence ID" value="KIC71661"/>
        <property type="gene ID" value="DB41_AS00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="226" mass="25225" checksum="8578A33926D500F1" modified="2015-04-01" version="1">MTLDKIDEIKKIGSSKLNANAEAEGLVNKDHFESLMLQQEQQQKQQKEVMTVEKIESTHTKPTLMEQVAELNKKVDQVKKVQPVDIVAQAQDVMSRMSQIQDQLALPGQAIKPAYRNLLKNKLTHINDNLRIALSAAGVENVPPAPQAISPNPIDRFLGFLTDGQAQLKSITKEVQYMHLNKNNINAAAMLAVQIKVGFIQQELEFFSSVLNKALESTKTIMNVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMN4</accession>
    <name>A0A0C1JMN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Yop proteins translocation protein T</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">yscT</name>
        <name evidence="8" type="ORF">DB41_AF00120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71826">
        <property type="protein sequence ID" value="KIC71826"/>
        <property type="gene ID" value="DB41_AF00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2154"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC71826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="243" mass="27115" checksum="E2A3A6E206B16ECC" modified="2015-04-01" version="1">MPQPAKVALGIGLFIIFLPQLLLVTHKIDFNLKLVFLIFKELFVGTIIGFLISLPFVIVQSAGIIIDHQRGGASLMVNDPTIQNQSSPLGTLFNYVMIWIFFMIDGPFLFMDAILTSYEVIPADQIINPKFFERSSVFWANEIALLNKIMVISIRLASPALIMIMMTDFFLGIANRLAPQVQITFLGMPLKSLLALLIVCVGWKMLNEEMAKQGYVWINEVINMLRTIKGSVSGFNEVGAVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMU1</accession>
    <name>A0A0C1JMU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Proline--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="7">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">proS</name>
        <name evidence="9" type="ORF">DB41_KI00190</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72575">
        <property type="protein sequence ID" value="KIC72575"/>
        <property type="gene ID" value="DB41_KI00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1916"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="SSF64586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="53"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC72575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="513" mass="59045" checksum="5755B306E5590312" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN42</accession>
    <name>A0A0C1JN42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AC00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71981">
        <property type="protein sequence ID" value="KIC71981"/>
        <property type="gene ID" value="DB41_AC00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5690" checksum="05A1DAFCD5921ABB" modified="2015-04-01" version="1">MFFSDKAKNQSHSFNQTKIAAPLNRQNLWLLLNAWKAPFSLNLSEIKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNR6</accession>
    <name>A0A0C1JNR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KR00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386513.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72181">
        <property type="protein sequence ID" value="KIC72181"/>
        <property type="gene ID" value="DB41_KR00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134797" evidence="1">
        <location>
            <begin position="21"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="70" mass="7233" checksum="A63A343F33C10615" modified="2015-04-01" version="1">MKILLSLLGASFLAASFLTAAPAMNNCECSQCTCTQDKHCGCYAKSGCHGLSPTATGEESSQEKNSSIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JP56</accession>
    <name>A0A0C1JP56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KO00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386436.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72316">
        <property type="protein sequence ID" value="KIC72316"/>
        <property type="gene ID" value="DB41_KO00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="624" mass="72864" checksum="41DB3A5067BE3073" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRR3</accession>
    <name>A0A0C1JRR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JQ00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386192.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73156">
        <property type="protein sequence ID" value="KIC73156"/>
        <property type="gene ID" value="DB41_JQ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="316" mass="36320" checksum="DBCB45D1ABA68D31" modified="2015-04-01" version="1">MNILIYVMSLLMMLTLLTYGRLEIYRSFVITQKELERYRSRIGHLAIDNGAQQWYAWTTFSSKENSKKNSAPKEASPLINLYWLLHPEARNFYPQVEATYRELLKKIIHQVFGEQTNFKEALNINPQLVDDLIQAIEAAGHKLALENNPIKTKNGLENLDLGQPFLQDIYYSLLKGYNLSPSVNLGNKHLNLPTENITALDSNENNKSLDEGFEEYKHTAHTISLLDFVTLNPQKTKIRVYLAPKAILLAIFGDPSTVEEILQQRISLYYQVKKAEDNQLATEQFKHAFATRAINMPETMLDFTVTATDPRHYKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTI7</accession>
    <name>A0A0C1JTI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_3</name>
        <name evidence="3" type="ORF">DB41_IP00200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243999.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74420">
        <property type="protein sequence ID" value="KIC74420"/>
        <property type="gene ID" value="DB41_IP00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1651"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="433" mass="49480" checksum="0AEA5581709094EE" modified="2015-04-01" version="1">MNPNSSITIEHLPNEILTPILTVCTSPALVSVCTRWRHLVNAEIMPSLYKQIGKIHFPQRDIREQTFILDRIYKLEEELTETAKVNAIFKQIFSLANSLSPVELEFKWKTEEKRYFNLANYSSYLININRLLMWKNLSDGTKYLEQEKIRYLPLAKKGELFREWIERYGQDIEELYLNEISLTFLPPEIGQFSQLWRLDLNNNQLTSLPAEIGQLSQLEYLCLEDNQLTSLPAEIGVLSQLQELYLNSNQLTSLPVEIGQLSQLGGLHLNNNQLTSLPAEIRQLSQLEYLCLEDNQLTSLPAEIGQLSQLGGLHLNNNQLTSLPAAIGQLVQLKNLYLKGNQLASLPAEIGQLSRLEYLCLEGNQLTSLPAEIGLLSQLKRLYLFDNQLTSLPAEIRHLSQLEELHLPYNQFTSLLAESGQLSHIYLLCLNHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUT0</accession>
    <name>A0A0C1JUT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IT00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386059.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000151.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74141">
        <property type="protein sequence ID" value="KIC74141"/>
        <property type="gene ID" value="DB41_IT00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002147965" evidence="3">
        <location>
            <begin position="27"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="132" mass="15156" checksum="31F0AE5241AE84D1" modified="2015-04-01" version="1">MYKRYGFFIAFSFLSMGIFSSLTLQADENQKIKGNLLIAQGKGHHGGRNGHHKGGHHDRDEKHHDHRHGGGNNYYYYGGLGIGLGFGASYPYYYDSYRGPSSSYYYPSSYSIYLNPSYPAPYERRLESRFPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVQ6</accession>
    <name>A0A0C1JVQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HV00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243950.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75135">
        <property type="protein sequence ID" value="KIC75135"/>
        <property type="gene ID" value="DB41_HV00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007163">
        <property type="entry name" value="DUF368"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37308">
        <property type="entry name" value="PTHR37308"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04018">
        <property type="entry name" value="DUF368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="410" mass="45108" checksum="53591818EB6A606C" modified="2015-04-01" version="1">MTLLLLKPSHKLPLAAARGWLCLICLGLCMGTADIIPGISGGTIAFIMGFYEDFLYSLKTLNRSAFKTLLKGHFRKFFNLIAWKFLLGLLIGIILAMLCLAHLVSYLLNHETYRSLLYATFFGLIIAATLLCMGQVKRWTLSSIFLFASSASLAFFLTQSSSMLSSSTADNLYDIKIDNIVSDKPLRNYNFSTHTLKAVPASMLSAMLAKEAIPPTTLAYSYKLATWGPLEFFLPNSKSKSLDPWIIFCGALAVCAMILPGISGSYLLSILGMYTIAVGALADFSSSLKNGHFDHPSFLILANLLLGIFLGALFFSRFISWILDKHHDLAIASLTGFMIGAIKAVWPFWSYQYALLPLHLEKGAQLETLEPILPSWTSYETWLALGLTVCGALLVFGLHIAAKSLQKRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVX3</accession>
    <name>A0A0C1JVX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_IJ00120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74541">
        <property type="protein sequence ID" value="KIC74541"/>
        <property type="gene ID" value="DB41_IJ00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="PTHR13610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC74541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="182" mass="21258" checksum="E1237D10B76FFA51" modified="2015-04-01" version="1">MIKRSIKCFMIFLLPLLLLLFILIIVWSIKNGIGPMPTSPPVKQILLDNLPLQEKGLIYELGAGWGTLAFLLAHKYPQCTILAYESSPIPYFFCRIRHFFSRSPHLHLQYHDFFKANLTDAKMIICYLYPVAMQKLKKKFEEELPKGAWVVTHTFAVPSWKAEQIIEVPDLYSTKIYIYRYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVY3</accession>
    <name>A0A0C1JVY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IJ00220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243990.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74551">
        <property type="protein sequence ID" value="KIC74551"/>
        <property type="gene ID" value="DB41_IJ00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1602"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="87"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="137"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="206"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="224"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="249"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="274"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="299"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="37984" checksum="A49907DEC7606926" modified="2015-04-01" version="1">MEINFLSNLCATIDNKLDYVPVVSSITNLVDIFQKCVLLNFKKNITLSHYYDYLDRKSFKRCVVLLIPVLGNIIVGVYDFYRYSMRDKSYMLRRLSQKGLELKYASSELKQDKEVVLIAVKQNGLALQYASPELKQDKEVVLVAVKQNGLALQYASEDLKNDEDVIVAAFIENKLALQYVGQEFRKNNEDEIIDIFMKNKSCVHAIVKVEGGMLKYASEELKNDKEIVLAAVQQEGWALQFASEELKNDKHIVLAAVQQKGSALQFASEELKNDKEIVLAAVQQEGSALQFASEKLKNDKEIVLAAVRQNGRAIHSASEELKKDKDIQRIAAQQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWP2</accession>
    <name>A0A0C1JWP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71647">
        <property type="protein sequence ID" value="KIC71647"/>
        <property type="gene ID" value="DB41_AS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13612">
        <property type="entry name" value="DDE_Tnp_1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="32"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="10923" checksum="2B54D6554950DB37" modified="2015-04-01" version="1">MTGSLSPVFLRTFLAKCLPTRDIYHTSYYQAYDKGLEIITRLRKNLKNKLISLVDRILLRKRGIIESVKNKLKNSCQIEHHRHRSLWNFLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWP6</accession>
    <name>A0A0C1JWP6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF772 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386793.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71652">
        <property type="protein sequence ID" value="KIC71652"/>
        <property type="gene ID" value="DB41_AS00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="1">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7630" checksum="DEEC60EA4ED99C06" modified="2015-04-01" version="1">MIEWKRLEEEFDKLFVKNVGQPARPVRLVVGLFILQHMDGISDEKVVHRWVENPYWQYFLWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWU3</accession>
    <name>A0A0C1JWU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AQ00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71717">
        <property type="protein sequence ID" value="KIC71717"/>
        <property type="gene ID" value="DB41_AQ00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6704" checksum="92F58108C90BE9C4" modified="2015-04-01" version="1">MQIKEVKELIFEVPYDKAVVIVEGYQAFESTSCYAGFEQRWVVIFSQVTYQREYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWV8</accession>
    <name>A0A0C1JWV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AN00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000211">
        <property type="protein sequence ID" value="KIC71732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71732">
        <property type="protein sequence ID" value="KIC71732"/>
        <property type="gene ID" value="DB41_AN00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2184"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="253" mass="28443" checksum="78A67BCFB9AED41B" modified="2015-04-01" version="1" fragment="single">TALDLSRVGLTYLPPEICQLSQLQELNLSRNQLASLPAGISQLSQLQEFNLHRNQLTALPTEIGQLSQLQWLDLSQNQLTSLPVEIGQLSQLQELDLHRNQLTSLPAEIGRLPELRALYLKNNQLITLPAEIGQLSQLGTLELDSNQLTTLPTEIWQLSQLKLLYLDNNQLTTLPAEIGQLSQLQVLDLNQNQLTALPTKIGQLSQLRVLKLGQNQLTTLPTEIEQLPQLQTLELAENPLKDIAKKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWW6</accession>
    <name>A0A0C1JWW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AM00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000210">
        <property type="protein sequence ID" value="KIC71742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244109.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000210.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71742">
        <property type="protein sequence ID" value="KIC71742"/>
        <property type="gene ID" value="DB41_AM00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002152322" evidence="1">
        <location>
            <begin position="27"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="169" mass="18070" checksum="CE133253CDB115F2" modified="2015-04-01" version="1">MKKRDLKKLALLGVAGGMMLSQSVHAQQTSSHAYLTLLAAASTPEKSTPTSAPSTAITQAEVDPNAGNLGYHLMDEEELLLELNEEGQQNYKALDVANQKLAREVASARCGNTNQCKGLNACKTDKHECAGQGSCKGQGKCAIADKNLAVKLVYDKMTKKGHLLTEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX11</accession>
    <name>A0A0C1JX11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB01040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74971">
        <property type="protein sequence ID" value="KIC74971"/>
        <property type="gene ID" value="DB41_IB01040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="7966" checksum="9EB7A89226AA03FE" modified="2015-04-01" version="1">MFRLSFRREKAASCASYFANNLKLYIANFFSAWLNRRSVIQNERKVGKCIAALSVVKKTFLFSVPDENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX24</accession>
    <name>A0A0C1JX24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">nusG</name>
        <name evidence="9" type="ORF">DB41_HY00070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385542.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74981">
        <property type="protein sequence ID" value="KIC74981"/>
        <property type="gene ID" value="DB41_HY00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1402"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="182" mass="21051" checksum="C544926B4E5B73F2" modified="2015-04-01" version="1">MHKWYVVQVFSTHEKKVKKALEEHRDLKGMSELIEKILLPIENVSEVKKGQQKIIERRLWPGYLLVKMTLTDESWHYVKQTAGVIEFLGGDKPTALSDAEVEEILRDLEDKKQKVTQRHKFEIGDKVKIIDGVFVNFIGTVSEVFHDKGRLSVLVSIFGRDTRVDDLEFVQVEEINEEAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-12-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXD8</accession>
    <name>A0A0C1JXD8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">smpB</name>
        <name evidence="4" type="ORF">DB41_HH00280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75735">
        <property type="protein sequence ID" value="KIC75735"/>
        <property type="gene ID" value="DB41_HH00280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1226"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="160" mass="18680" checksum="D758015071060766" modified="2015-04-01" version="1">MRLHLIYLHMNNKSSDLVSNKRAFHHFEILETFEAGIALEGTEIKSLRDNGGSLQESYIKVINREAWLIGSHIAPYKYGNIHNHLETRDRKLLLHKREIFKLRESVQEKGLTIVALALYLKEGRVKVKIAIAKGKKSADKREAIKERDEKRYMQKMLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXN9</accession>
    <name>A0A0C1JXN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GZ00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384955.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75845">
        <property type="protein sequence ID" value="KIC75845"/>
        <property type="gene ID" value="DB41_GZ00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="26"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="270" mass="30601" checksum="C33B9FE3FD12FF19" modified="2015-04-01" version="1">MTRNKFVHFLFMTLIIQSSLKGEEICAIGHIQPSSKSLMGAQVSGRVEKVLVEVGDKVVKNQPLVQLDKNYYEIELALKTAALEGARVELSDAEKNFLRMQKLWERPDGQLPSIPLKKYEEAKSKYDHSLIHVKQFQEDLKRAQLYWEETTIKAPFEGIITKKLVDVGEYITVQPVTSMVEIQALNPLYLEFSIPQVYASTLRLGTPLSFEIDGTHLDCNHAQIDLFYPTLDETTHSLRCRAILDNSDYKIRPGSLARVIIKAGQVANNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXS3</accession>
    <name>A0A0C1JXS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyguanosinetriphosphate triphosphohydrolase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dgt</name>
        <name evidence="2" type="ORF">DB41_GZ00340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75870">
        <property type="protein sequence ID" value="KIC75870"/>
        <property type="gene ID" value="DB41_GZ00340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1099"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="118"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="49321" checksum="E351E70902564492" modified="2015-04-01" version="1">MERLFSISYSSWVITQTTCFINYFSLRFTMRNFSKNECKYMTIPFSETLSFYRHALIKQEKAYLHPLAARTSTHSRQAGNEEDYRLPYKRDVDKIIHSRAYARYNDKTQVVYLVDNDHITHRGLHVQFVSSFARGIAEILRLNLDLVEAISLGHDVGHPPFGHEGEEYLSELSIMFENGAFAHPLQSCRLFTDIEPLNLGLAVYDGFLCHDGAMSSSLIHPSFDKTWEDHFNDKKQKAREPDYNIIPGTLEGCLVKLCDTMSYIGKDIEDAIRLGIISKEQVPKTFLGTTNQEILATLAKEIIKVSYEQAYIGISMEAFEALKFLRDFNFAHIYVHPQLKVESSKIKRAYRLLFELLLEDLNHLNEESYVWKNYTFNKNEHYKNSTSLVQMVVDYISGMTDSFFIRTLEKLTLPRRIDLRECFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY46</accession>
    <name>A0A0C1JY46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GT00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000105">
        <property type="protein sequence ID" value="KIC75975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75975">
        <property type="protein sequence ID" value="KIC75975"/>
        <property type="gene ID" value="DB41_GT00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="7895" checksum="E375EB7E8FBDF9E6" modified="2015-04-01" version="1" fragment="single">MDGKRLKGVSDNSPYAQMSRKNYYKSIFFSLKRGKKMKLDLLDIYTDYLISQNQQAKATGLSNLLDGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY74</accession>
    <name>A0A0C1JY74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GR00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384844.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75995">
        <property type="protein sequence ID" value="KIC75995"/>
        <property type="gene ID" value="DB41_GR00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="920" mass="108340" checksum="55F9DC0DAC71C71A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYD5</accession>
    <name>A0A0C1JYD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 12" type="primary">recA</name>
        <name evidence="12" type="ORF">DB41_KR00150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386525.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72192">
        <property type="protein sequence ID" value="KIC72192"/>
        <property type="gene ID" value="DB41_KR00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2045"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="10">
        <location>
            <begin position="40"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="11">
        <location>
            <begin position="204"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="307"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC72192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="356" mass="38313" checksum="A1EE371C0E756BD3" modified="2015-04-01" version="1">MAQANDAERKKALDLAVSQIKKQFGDGAIMSLGKHSSEREISVIKTGALSLDVALGIGGVPRGRVVEIYGPESSGKSTLALHIVANAQRNGGVAAYIDAEHALDPGYATKIGVNIDNLLISQPDSGEEALNIAEALARSNAIDVIIIDSVAALVPKSELEGEIGDTHVGLQARMMSQALRKLTSALAKSNTCAIFINQIREKIGVMYGNPETTTGGRALKFYSSVRLDIRRTAGIKGNENVEIGNRVRVKVAKNKMAPPFLTAEFDILFNEGISRTGTVIDMAAEYNIVDKKGAWFSYKGQRLGQGREAVREELKNNTKLLEELETLVLEHLNNKIAAKTSKASEAEESLAELMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYF0</accession>
    <name>A0A0C1JYF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HK00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000121">
        <property type="protein sequence ID" value="KIC75511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385313.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000121.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75511">
        <property type="protein sequence ID" value="KIC75511"/>
        <property type="gene ID" value="DB41_HK00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="21"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="81"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="690" mass="77825" checksum="CF907EDB121920FD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ30</accession>
    <name>A0A0C1JZ30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GL00060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76265">
        <property type="protein sequence ID" value="KIC76265"/>
        <property type="gene ID" value="DB41_GL00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901663">
        <property type="term" value="P:quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="77" mass="9044" checksum="AB062D57D329BA7E" modified="2015-04-01" version="1">MNFYNKDNPESLQQMFGSIAQQYDKTNAILSFQMHRLWNKKLIWAVMKNQNPSTYLDLCCGTGEIAFKYLKKALFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ91</accession>
    <name>A0A0C1JZ91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">MEP cytidylyltransferase</fullName>
            <shortName evidence="7">MCT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">ispD</name>
        <name evidence="8" type="ORF">DB41_KJ00120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386375.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72537">
        <property type="protein sequence ID" value="KIC72537"/>
        <property type="gene ID" value="DB41_KJ00120"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018294">
        <property type="entry name" value="ISPD_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01295">
        <property type="entry name" value="ISPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0808">Transferase</keyword>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="7">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="227" mass="25237" checksum="60FB38AFB1DFD7B6" modified="2015-04-01" version="1">MTSQEVSVILLCGGQGLRMQNATPKQFLTLHNKIIATYSLDVFKTLPEVIEIVVVCDPAYQKFFTSPELSVPLKFACPGRHRQDSVFNGLKALTSQAGFVCIHDSARPIITPPLVQRVLKAAFQHGAAAAGMPIKFTIKEHDGNHIVKQTPDRSTYWEVQTPQVVRKDILEQGFAYALKNHLKVTDDVSLVEHLGHPVKLVEGCYTNLKITTAEDLILAKYLLHEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZI3</accession>
    <name>A0A0C1JZI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4277 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GF00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384592.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000091.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76415">
        <property type="protein sequence ID" value="KIC76415"/>
        <property type="gene ID" value="DB41_GF00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8534" checksum="6420DB4289183327" modified="2015-04-01" version="1">MILNGLEFESRTLYMYSEYFEDKPIDHLLGTPVIPERIDDNVLGRMETMRAYQNNGENFRKRQQHAGCFSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0C2</accession>
    <name>A0A0C1K0C2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384172.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76610">
        <property type="protein sequence ID" value="KIC76610"/>
        <property type="gene ID" value="DB41_FI00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.693"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="348" mass="40440" checksum="CC8B10A40EE7AD11" modified="2015-04-01" version="1">MNIEDISEDTERLVWDKPYFYYQGKIFNPNLYEWQAEDEEIPAGYNVISLKLDGKVTASLDWKKIEKVAEYYSKEGFLLFWDLDLGLFDRLEFPLSNQTQFLSLLLSLEHFRDNLWNKFKAQTLGVNIYRGPVNFKSQMSWDDELQSNYKEWKTTRGNENDQLPFSTSQALFACEVGAEYLTLLANRMPDEMPIFVTLNKDLSLSLGLEVQLTHRERWGRLHLIIKNSKLPHLFNFKPAPIGICLPHYQWRDQQTYQELEDILHDLLNKEVAFNIIPENYLLHEWEGLDYLVVISPSLTRQGKRNLQGFCAAGGTAITVGPSLGLAKEIPYVKSEKGFFSMMNNKDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0N1</accession>
    <name>A0A0C1K0N1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EU00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76725">
        <property type="protein sequence ID" value="KIC76725"/>
        <property type="gene ID" value="DB41_EU00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6247" checksum="8B5732A9C4A38F4E" modified="2015-04-01" version="1">MNPFFCKKDDALREKNLWIGYQTKSSFNLNTIKILISGSYPLPVSIHFKDKIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K140</accession>
    <name>A0A0C1K140_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76855">
        <property type="protein sequence ID" value="KIC76855"/>
        <property type="gene ID" value="DB41_EC00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="8051" checksum="3DA23A1CD5AD55F1" modified="2015-04-01" version="1">MPYLKGLKMKNAELHKKLAHLESMNDVLITEIENIHELMKMIGFANGINTLKTTAEGMIYSGYGNVSNYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1D5</accession>
    <name>A0A0C1K1D5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FP00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000077">
        <property type="protein sequence ID" value="KIC76551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76551">
        <property type="protein sequence ID" value="KIC76551"/>
        <property type="gene ID" value="DB41_FP00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10885" checksum="C0A456E71ECA89D0" modified="2015-04-01" version="1">MSTKRKRHSSEFKAKVALEAFKGFKTINELATEYSVHPTQISQWKKHLIEALPVLFSSMDKVSKTDQKLVDNLYQQIGRLKVELDWLKKNYTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1E7</accession>
    <name>A0A0C1K1E7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76561">
        <property type="protein sequence ID" value="KIC76561"/>
        <property type="gene ID" value="DB41_FN00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6808" checksum="43BD425FCFD83DAA" modified="2015-04-01" version="1">MPNLATHQKVIKNTLGVSKLAETLGNIFYACKMIEYFRIAFIDLKNFMKKVERQLFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1P0</accession>
    <name>A0A0C1K1P0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">dapA</name>
        <name evidence="11" type="ORF">DB41_FI00110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384160.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76601">
        <property type="protein sequence ID" value="KIC76601"/>
        <property type="gene ID" value="DB41_FI00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.684"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="294" mass="32333" checksum="3EE60D86C227FB5D" modified="2015-04-01" version="1">MQPKICGAYTVLITPFDKEGQLDEEGLRKNIRFQLSYHIQGLVVLGTTGEAPTLSQKEKEKIISIAREETEGKCLLMVGTGSYATHATIENTLAAQDASADAALVVTPYYNKPTQEGLYQHFSTLAKAVKLPLVIYNIPGRTGQNLQIETLKRLAVIENIVGVKEASGNILQMMDVIESIRLIRSDFSIMSGDDALTYPLMALGGHGIYSVLSNLLPQEVKKLCDLMVEGDYPTARALHYELLPYMKSMFIETNPIPVKTAMNLAGHAAGPCRLPLCAMSDENLKKLKKCLKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K270</accession>
    <name>A0A0C1K270_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">yfhQ</name>
        <name evidence="12" type="ORF">DB41_JJ00040</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000166">
        <property type="protein sequence ID" value="KIC73472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73472">
        <property type="protein sequence ID" value="KIC73472"/>
        <property type="gene ID" value="DB41_JJ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1762"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="11">
        <location>
            <begin position="44"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC73472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="165" mass="19208" checksum="B80037FD2A90E53A" modified="2015-04-01" version="1">MHILLGFMYSIDSKRLKEWFLAEKRTLPWRNHPSPYAVWVSEVMLQQTQVSVVIPYFHRWMQRFPSIASLAEADLDEIIKLWEGLGYYSRARSLHQAAQYVVTHHQGQLPSNEEELKKIKGLGPYTVGAILSFAFRQRAAAVDGNVIRVLSRYFEIKEDFAKKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K279</accession>
    <name>A0A0C1K279_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="9">1.4.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pdxH</name>
        <name evidence="9" type="ORF">DB41_DB00070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="6">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383347.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77100">
        <property type="protein sequence ID" value="KIC77100"/>
        <property type="gene ID" value="DB41_DB00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.198"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0288">FMN</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="7">
        <location>
            <begin position="33"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_phzG_C" evidence="8">
        <location>
            <begin position="171"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="190"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC77100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="211" mass="24901" checksum="20310968E94C8878" modified="2015-04-01" version="1">MNLEELRAEYAKKVLKREDLQADPVKQFQAWLEEAYALQILEPNAMVLTTCSKAGLPSIRTVLLKKVDEKGLTFFTNYESRKAQEINENPQVSVIFLWKELERQVIIQGLAEKTSREVSMNYFDKRPRQSQLGAVASHQGRILSSRKILEEEYERLSVIYEGLKIPCPEKWGGFIIKPYYYEFWQGRTNRLHDRFSYHFAEQIWHIQRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2A5</accession>
    <name>A0A0C1K2A5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridoxal 5'-phosphate synthase subunit PdxS</fullName>
            <shortName evidence="3">PLP synthase subunit PdxS</shortName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Pdx1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">pdxS</name>
        <name evidence="6" type="ORF">DB41_CZ00110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">In the presence of PdxT, forms a dodecamer of heterodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383328.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77130">
        <property type="protein sequence ID" value="KIC77130"/>
        <property type="gene ID" value="DB41_CZ00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.186"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PTHR31829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00343">
        <property type="entry name" value="TIGR00343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="SOR_SNZ" evidence="5">
        <location>
            <begin position="14"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribose 5-phosphate binding" evidence="3">
        <location>
            <begin position="242"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="301" mass="32317" checksum="4BF308958BEB0679" modified="2015-04-01" version="1">MLKNGNAHPGTGSFAVKVGLAEMLKGGVIMDVTTPEQAKIAEDAGAVAVMALERIPADIRAQGGVARMSGPELIHKIQEAVSIPVMAKCRIGHFVEAQILEALFVDFIDESEVLTPADEENHIDKHAFRIPFVCGCRHLGEALRRIGEGAAMIRTKGEAGTGNIVEAVRHLRTLNREMRVLTTMDNSELMAEAKRLGAPYHLVKQVAEKGKLPVPNFAAGGIANPADAALMMQLGAESVFVGSGIFKSEDPSQRAKAIVGAATYYNDPEMLAKISMGLLSAMKGLDIQQIRKEDLLAQRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2G4</accession>
    <name>A0A0C1K2G4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76856">
        <property type="protein sequence ID" value="KIC76856"/>
        <property type="gene ID" value="DB41_EC00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="65" mass="7218" checksum="B6CF2899F019AFB1" modified="2015-04-01" version="1">MNKKQLEQKIAFLESINDQLSTEVTYIDQLMKLIGFAGGVDTVKATATEIIKKGYTITNLPEDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2H3</accession>
    <name>A0A0C1K2H3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rnc</name>
        <name evidence="10" type="ORF">DB41_CR00040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383188.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77210">
        <property type="protein sequence ID" value="KIC77210"/>
        <property type="gene ID" value="DB41_CR00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.96"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="11"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="165"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="243" mass="27503" checksum="FBE004AAFEE87950" modified="2015-04-01" version="1">MNAYDELMKRATEIEHKIGYTFKDRALLALAFVHRSYVNENKEVGKHNERLEFLGDSVLGMLIADYLYRYLPSTSEGELSVLRSRLVEASSCFNYVQKYGLGQYLLLGKGERMNDGRGRESILADLFEAIIGAIYLDGGLEVAKHFLFKNFSAEIEAILKMPLRNFKALFQDYCQKNFQQTPTYKVLGEEGPDHSKIFKICVMVHDQAKGYGHGSSKKEAQQAAAADALAHYRVIANQKIKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2H5</accession>
    <name>A0A0C1K2H5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JG00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73562">
        <property type="protein sequence ID" value="KIC73562"/>
        <property type="gene ID" value="DB41_JG00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="7299" checksum="FFE0BD7146B309B0" modified="2015-04-01" version="1">MALFKVYKKTAPFFYLHRGYHQSLNNLFYFLAHLLCKAPQLAREWLFAISEKKLKNLLILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2L1</accession>
    <name>A0A0C1K2L1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DS00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383614.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76926">
        <property type="protein sequence ID" value="KIC76926"/>
        <property type="gene ID" value="DB41_DS00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="229" mass="24563" checksum="1F792E7478CE3EEA" modified="2015-04-01" version="1">MSAILPRDFSSTPGMDSVQKTQGVKKDFIELSTENPGKGLPKLTTAAKQMKESKALHALATIGRVTAGTIGIVALIPLVPVAMSLHFFIAAALAPAGDVVNNAIKKSTGYEIERGSIGLADAFLGLYFTTFELIGNWMIGEKKSHPGVQVAENSSVPVEQAITPGSVVITPKTSSSFKSSMQAEEEEPELEHHPIPAATFFKADNEEKREAAPELTEREENSLKAKKHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K358</accession>
    <name>A0A0C1K358_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CX00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383308.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77151">
        <property type="protein sequence ID" value="KIC77151"/>
        <property type="gene ID" value="DB41_CX00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="464" mass="53327" checksum="63D9F677C6C6367A" modified="2015-04-01" version="1">MQSDSSFHLKQQLGYFREIENNFESEQVELSAADKVKRAHVIMIGESHGFAQAEISSLVNTIALEHLAKNDLDRIAILDESEEASEARTVEFRSIKREYNDRLIFGCWDNPLSRKSMPLFANQVIQWTYSNMLHGMTQYLSEREVEGLSYMHDTMKEAINKLILWSKKEEMIEEGYARILEQNAEKLSEIVEGIKADLSKLIDKKGLTSYDLKHLQANSIIKSYSFMDNFSEILQALTVHPLDRRNRDGEANINRALQSCEKVVVIAGRSHLKVLHASAELEEKTNIKKGIQPLYHGLVKRTSRDTHLHYVVLETPPPEEGLPAIRAIPDNLREEKHDQSLREQLGEIETLPERKIKGKEKDSEETNMFQINDSIYQSIENKLEELNNIKSIVDIGKKFTEINSLIKNNRHQLGFIQVNEMCKSLIINTLQQLRVIELDRISTSIPQGESVALKITRFFSKLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3B5</accession>
    <name>A0A0C1K3B5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="2">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lpxB</name>
        <name evidence="10" type="ORF">DB41_IY00030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386080.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73807">
        <property type="protein sequence ID" value="KIC73807"/>
        <property type="gene ID" value="DB41_IY00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1696"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC73807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="387" mass="43667" checksum="89D2EC0A85AB627F" modified="2015-04-01" version="1">MKSNDNLHPHLFIFAGEPSGDLHGAHLVKAFKELYPSCWFSGVAGPALREEGIVNIMPMEKFAVMGFSDVIKALPSLYKQFYYIRDYVLSTCPELVIFIDYPGFNLRMARALRKAGYKGKLVHYICPSVWAWGKKRIQHMAKTLDMLLTIYPFENISFKPTSLKVQYVGNPLQEYISQHLYAPSWKSHFCPPEHLLISIFPGSREAEIKNNLSKQLEAALLFQKENPSTAFGISCSNASLKPLIEKILKKHRLLHAFIVDKAHTYDLMRNSHSAIAKSGTVTLELALHCCPTVVVYQLSTLNWLIAKFIIKLNLPYYCIVNILSCQRLFPELIAEGFTPKKVAKELEDIHAGSSRARCLEGCQQIVELFQGTHASQNAAQAIHSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6N1</accession>
    <name>A0A0C1K6N1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74902">
        <property type="protein sequence ID" value="KIC74902"/>
        <property type="gene ID" value="DB41_IB00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="136" mass="16236" checksum="250B4BE5EB4D62BC" modified="2015-04-01" version="1">MGPTWWGVEDNENSCQAVIREVLEETGLTVKVLRKVAEYTPINKLSRFTEIYECSPLKGELQKGAETREIDFFPLQQLPSHFFFLHKEWLQDALRNESHVIYRSLNHVTYINLIKYFFKHPTWVLRFLMTLMKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6U5</accession>
    <name>A0A0C1K6U5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74957">
        <property type="protein sequence ID" value="KIC74957"/>
        <property type="gene ID" value="DB41_IB00900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="8451" checksum="C58521FA13C177F0" modified="2015-04-01" version="1">MPLLSLATRWSFLQSNSHLNQFAINPSVICFKTTFYTIIQLIKTSFLKESCHKGDSPFRLRRRRVFKRYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K717</accession>
    <name>A0A0C1K717_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HX00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000134">
        <property type="protein sequence ID" value="KIC75017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75017">
        <property type="protein sequence ID" value="KIC75017"/>
        <property type="gene ID" value="DB41_HX00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="97" mass="11204" checksum="875C7BB7885256C3" modified="2015-04-01" version="1" fragment="single">FLETIRRIYAQQRNDFRKVYSLHEPHEECIAKGKVEKKYEFGCKALLVTTHQEGLALDVRAIHGNPYNGHTFEEAIKKAQNNNGNSSLIRNLFFALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K851</accession>
    <name>A0A0C1K851_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spore coat polysaccharide biosynthesis protein SpsE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spsE</name>
        <name evidence="3" type="ORF">DB41_HO00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75362">
        <property type="protein sequence ID" value="KIC75362"/>
        <property type="gene ID" value="DB41_HO00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1312"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="479"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="521" mass="58790" checksum="CC3463E4D2F06828" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9D0</accession>
    <name>A0A0C1K9D0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HF00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385132.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000116.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75777">
        <property type="protein sequence ID" value="KIC75777"/>
        <property type="gene ID" value="DB41_HF00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="967" mass="112224" checksum="9A2CBCA09800C28A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBN3</accession>
    <name>A0A0C1KBN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FQ00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384306.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000078.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76542">
        <property type="protein sequence ID" value="KIC76542"/>
        <property type="gene ID" value="DB41_FQ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="263" mass="29500" checksum="F9640114A76A62AD" modified="2015-04-01" version="1">MTPISTSSAEYKQFKEAFTQYAQYTAAVNNLRIFVEENKESYKAHLQEEAKQIAEKKAALDARMVDISARKEELAAKKGELAAKKGELAARKEQLNTREAELDATLEQLAKTRIDAEIKLAQAEAKIERGRALSKLADVRVFCTALGLPQPQENDVEKINQIASTYFPNGEIGDINGQITLFSMSPIEKFISETGSTTNKLNFTPIRIVHDPKNLVEFLQKPGCRIKFLGFDARIKDTLEQQLDAVCPKEGRTFKIMYVAPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBP8</accession>
    <name>A0A0C1KBP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FN00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384287.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000075.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76557">
        <property type="protein sequence ID" value="KIC76557"/>
        <property type="gene ID" value="DB41_FN00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="525" mass="59889" checksum="3196670C1A16CEC0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBX8</accession>
    <name>A0A0C1KBX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="8">HTPA reductase</shortName>
            <ecNumber evidence="8">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">dapB</name>
        <name evidence="11" type="ORF">DB41_FI00120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243841.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76602">
        <property type="protein sequence ID" value="KIC76602"/>
        <property type="gene ID" value="DB41_FI00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.685"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="10">
        <location>
            <begin position="107"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="8">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="101"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="256" mass="28433" checksum="1FFBE08BF5EA3F17" modified="2015-04-01" version="1">MKIVLIGYGKMGHLIEEIALQQGHTIIAILPSNEAVSSLKENLIQQADICIDFSAPQAVLSNLQRLAPFKKNIVMGTTGWEEHLDEVKKLIHEHQIGFLFSPNFSIGVHLFKNIVEAAAQLMNEFEDYDVAGQELHHYQKKDSPSGTAKSLVSILLEKIQRKKNPLYDRVDRPIAPHELNFSSVRCGSIPGTHTIIFDSPADTLTITHQARNREGFARGALAAAEWLIGKKGIFTLEDMICSSKNISNTCHLQGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC32</accession>
    <name>A0A0C1KC32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_FC00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000065">
        <property type="protein sequence ID" value="KIC76657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243829.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000065.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76657">
        <property type="protein sequence ID" value="KIC76657"/>
        <property type="gene ID" value="DB41_FC00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002135032" evidence="8">
        <location>
            <begin position="29"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="425" mass="47384" checksum="D9513C2BACC46BD0" modified="2015-04-01" version="1">MVKFSFKKMIASLCFVPCLVLTPTSAHAVIASVKTFGMAATGIAYPQDAQAAVFNPAGMADVGDRYDLGFEVARTSRQATVRGNLSPLPGVNGKFDANHKAKYAYNGDFGINKMLGNNMSLGLVVYNRNFSKTKYKHALPLFGTSKVGMEYAHETISPTFSIKLLEKHNFGVSLNYMIQRLWVQGLQNFAKEAFGVGIFSKFPRYVTNHKYSYSQGVGFTFGYRCQVADRLSVGVTYQPKTYMSKFKKYKGFLAGKGRLNIPQKIGAGFAWRLLPYATLAFDVEYINWRKVKALHRPLQDNLTAHKLGAHNGTGFGFRDQWFYRLGIDYELTEWLIVRAGYRHTRAPIKRSQTAVNVLTVDTIEDYLTLGATACLNSSNEISVFYGHGFSHKIKGKNSIPSSFGLGEANIKQSDNVFGISWGHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCH3</accession>
    <name>A0A0C1KCH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rplP</name>
        <name evidence="9" type="ORF">DB41_EI00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383806.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76787">
        <property type="protein sequence ID" value="KIC76787"/>
        <property type="gene ID" value="DB41_EI00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.485"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="8">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="139" mass="15782" checksum="E0312769747FCFF1" modified="2015-04-01" version="1">MPLMPKKTKHRKTMKGSCSGLSKGATFVHFGEFGIQALERGWLTNQQIEACRVAINRYFQRKGKVWIRIFPDKPVTKKPQEVRMGKGKGGLDHWVAVIKPGRILFEVGNVSKEEAQHALRRAAAKIGLKTRFVERVEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD22</accession>
    <name>A0A0C1KD22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DQ00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76947">
        <property type="protein sequence ID" value="KIC76947"/>
        <property type="gene ID" value="DB41_DQ00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="216" mass="24576" checksum="4CB9D602865798FB" modified="2015-04-01" version="1">MEEGDSESLAIFQFAKEIFSLKLRPAGPLDSNPATNRQVVLNTDKFIPSLTRTAAQEDWLKFSHLQQLIGEMDKYNNRKDDISASELSSAVKMHAETRLLLFFHLSVAFFKSKSKIEPRGAKFQLYQGSEAQGTEACHHSLFPEIKDNYLEKLKQEALEVVRQERKGRENISPTLILKLLALGIPGEALQETLKQIIDKKRGAEEGINKLWDEFFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD89</accession>
    <name>A0A0C1KD89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Silver exporting P-type ATPase</fullName>
            <ecNumber evidence="8">3.6.3.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">silP</name>
        <name evidence="8" type="ORF">DB41_DN00130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.53" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243777.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76992">
        <property type="protein sequence ID" value="KIC76992"/>
        <property type="gene ID" value="DB41_DN00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.304"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="671"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="HMBD" evidence="7">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="723" mass="78527" checksum="A970BCC62FF819B2" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDB0</accession>
    <name>A0A0C1KDB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383511.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77002">
        <property type="protein sequence ID" value="KIC77002"/>
        <property type="gene ID" value="DB41_DN00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="205" mass="24040" checksum="41ED40B781AE2052" modified="2015-04-01" version="1">MAITLSVTSSCILPIKACSQKTGHASQVFARICKICSYLGARIKKIALEIFYYLQEFYKDLKDDLSIWWFEKEDPIDTEARIECEKLKPKIEELKQKTYLLDTFINERPELKAKCLEYYHKYKHLFIKNQRGSPRTRLAIDLDLNDPVDQLNILGVEKLDLEYELDQRIDFITSFKEVYTLFEKYVLEAEKASQGAENTFSLLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDH6</accession>
    <name>A0A0C1KDH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative folylpolyglutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folC</name>
        <name evidence="5" type="ORF">DB41_DH00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77062">
        <property type="protein sequence ID" value="KIC77062"/>
        <property type="gene ID" value="DB41_DH00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.245"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="4">
        <location>
            <begin position="50"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="408" mass="45345" checksum="A7C8FB77BBC55C35" modified="2015-04-01" version="1">MATNFSSYKELIKKLFSINKHGGMKLGLNNMCRLQRVLDFPTRHYQCIHVAGSNGKGSVTTKIAKALEAEGYRVGLFTSPHISTFRERVKINSQLIDEETTKTLLDKIFTKIANEQIPATFFEITTALALAYFAQKKVEYAVLEAGLGGRLDATNIVIPRLSIITSISLEHTEYLGQTVEEIAKEKAGIIKPGIPVIIGPRVPRPVIEEIAKLQNSPLTQVAGNFSNFDEENSAIARAALQTLAVSESSLQLGLKALPACRLELVCQAPPTLLDVGHNPDGLIHLFKAIRQKHPHMPLRIMFGLSKTKDVEGCLRVLKEYGEHFHLVEASNGRSIEVGALYQKMIEHHFPLSSISIDATISYTTQKALLLAKQNRQVLIICGTFFIMREVRASLKIEEPMDDYDINEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE71</accession>
    <name>A0A0C1KE71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transketolase</fullName>
            <ecNumber evidence="3 8">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tkt</name>
        <name evidence="10" type="ORF">DB41_CO00360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243738.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77267">
        <property type="protein sequence ID" value="KIC77267"/>
        <property type="gene ID" value="DB41_CO00360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.70"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="682" mass="74905" checksum="1F39188CB3654743" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H0D4</accession>
    <name>A0A0C1H0D4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BT00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000240">
        <property type="protein sequence ID" value="KIC71224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71224">
        <property type="protein sequence ID" value="KIC71224"/>
        <property type="gene ID" value="DB41_BT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="160" mass="18025" checksum="918B366F91D7E97D" modified="2015-04-01" version="1">MLLLPQLLQTLPHQPTTVNMSTPESSVKTAVLNLPLNLSSMSNNDVKKWCKDNWAIIEQEHITIASLKSLLKKLRASRTALNKKAAISKLLEIMRKEEEQGEEQLMRRGKQSCEECKEADQTWEEEEEEVAEHGRVEQEGGEVEEGDSGGVHLEACSRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H2V2</accession>
    <name>A0A0C1H2V2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AE00240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000205">
        <property type="protein sequence ID" value="KIC71949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244093.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000205.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71949">
        <property type="protein sequence ID" value="KIC71949"/>
        <property type="gene ID" value="DB41_AE00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="216" mass="24864" checksum="F347228603CDC243" modified="2015-04-01" version="1">MNPSSSITIEHLPNEILAPILKVCASPSLFSVCTRWRHLLSTEVMPSLYKQIGKMHFPQGDISKQAFILDKIYKLEDRLSEGEKAKAIFKQTFTLARSLAPAELEFKWKTEEKRYFTLDNYSSYLININCLLMWEKLPGGKEYLSQEKIKYLPLEKQEELFKDWIENHGKNIGNLSLVDVGLTFLPPEIGCLSQLQELSLTNNRLTTLPAEIRQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3S7</accession>
    <name>A0A0C1H3S7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KR00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72184">
        <property type="protein sequence ID" value="KIC72184"/>
        <property type="gene ID" value="DB41_KR00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7215" checksum="5D4BD1D347DA52D7" modified="2015-04-01" version="1">MLDSFPFLAVQIFRIAKHYASSAVEFAFILLKKGVALSYRRLINSSLAGIYLKAAFKEREAFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H441</accession>
    <name>A0A0C1H441_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pcrA_2</name>
        <name evidence="9" type="ORF">DB41_KO00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386433.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000194.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72314">
        <property type="protein sequence ID" value="KIC72314"/>
        <property type="gene ID" value="DB41_KO00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1980"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="5"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="283"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="26"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC72314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="726" mass="84026" checksum="EBD4DFD6089D03B1" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4N4</accession>
    <name>A0A0C1H4N4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KK00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72484">
        <property type="protein sequence ID" value="KIC72484"/>
        <property type="gene ID" value="DB41_KK00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="74" mass="8813" checksum="62D320CA78ECC750" modified="2015-04-01" version="1">MHARIFYWYLPFLLKIFNKFFASIERPASNHFVFNKTISFSQLIILVPYPRIPLMALASYLKFHLLAIYLATDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5G3</accession>
    <name>A0A0C1H5G3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KD00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72709">
        <property type="protein sequence ID" value="KIC72709"/>
        <property type="gene ID" value="DB41_KD00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="9753" checksum="6E83AE8FE1C11DB6" modified="2015-04-01" version="1">MGAERSEAVNAASVTEAMNTSSSTTPSSMAASPQNSERFTTISSMSDLKEKAPEMHKAMMQGLAMNICNGMQKHQQRFKEILRKGRSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5H7</accession>
    <name>A0A0C1H5H7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KD00240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72724">
        <property type="protein sequence ID" value="KIC72724"/>
        <property type="gene ID" value="DB41_KD00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5147" checksum="AD11B7763C4D8E64" modified="2015-04-01" version="1">MPYLAKHYLKGSEKEAKAFIKLMQQEFSCPSDAKRKLDKFAKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9P0</accession>
    <name>A0A0C1H9P0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rfbB2</name>
        <name evidence="3" type="ORF">DB41_AV00280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71588">
        <property type="protein sequence ID" value="KIC71588"/>
        <property type="gene ID" value="DB41_AV00280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2266"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="11"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="342" mass="38616" checksum="1A714729D0DA47C1" modified="2015-04-01" version="1">MKIKRKVSNILVTGGSGFIGSAFIRYLLKNVPHFKGLCLNFDLLTYAGNPQNLKEVENDPRYLFHQGDIKNEVFIEHLCREYAIDTIIHFAAESHVDRSIHGPKEFIETNVLGTFHLLEVIRRLPHIHFHHVSTDEVYGCLGNEGFFTESTPYAPNSPYSASKASSDHLVRAYGKTYHLSTCISNCSNNYGPYHFPEKLIPLTIINCLRKNLYLFMGKVLTYVTGCMWKIMPKRCGCYWKKEIQEKLTISEVKKSGATLISSMKSSKFLPRSSRLIKSLILSSLNTCKIAPGMTSVMPLIAPKLRKKSAGILITTSPKALRKLSYGTSIILYGLKMFNRALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAJ8</accession>
    <name>A0A0C1HAJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386021.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74409">
        <property type="protein sequence ID" value="KIC74409"/>
        <property type="gene ID" value="DB41_IP00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1640"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="171" mass="19436" checksum="6D790F8A1BB19D1D" modified="2015-04-01" version="1">MSTNSKSDSKQLESLIQTAVKKLGAKKENDICRYIPSSAGGYIHHFTMRKMKTEDPEQLTDMILKYIINVDKPSSVTPKQRAARGSRKRRDQILFSKQDIERMLNMARLAGDKEMIRKLTPKKDLRSIKRELIASIRHGKVEQDLWASYVEAISLNNNLAASANSLAPQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB20</accession>
    <name>A0A0C1HB20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AC00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386600.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000203.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71983">
        <property type="protein sequence ID" value="KIC71983"/>
        <property type="gene ID" value="DB41_AC00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="16505" checksum="D9A36764343EEFB4" modified="2015-04-01" version="1">MNGKGRATDNIFVERSRRPVKYEDVYLRDYQDKLEVYQGLIKYFEFFNKNLPHRFLKYKALAKEYGVIIYYEAIRDLLEELDKRQSTFVAQIPRNHALWPLDIPLNSSQNIRGQPRKCLRSYRVSNASKDTSRMHIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC68</accession>
    <name>A0A0C1HC68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HY00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243960.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74994">
        <property type="protein sequence ID" value="KIC74994"/>
        <property type="gene ID" value="DB41_HY00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="364"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="486" mass="55175" checksum="6BF178CBD833539B" modified="2015-04-01" version="1">MQVQNLSSHPLSNISPEIPVAEISPEVHKMLQNPELYDMVQGTLCGRLIKLLLARCNTTLEKHLYAYKAKGIILSKRLETVWGIAQATDNQEALDILYKYNPNLASICHIKLMAHRFSIVGKSQINGQSFDLEGFDHRITFQALYNSLKQHLEVTEQEMILPIIEMILKVEKDPHTKDQILIDAYHQGKTIFLPLIFKLATAGHIYGFLIKGNRLIKLNKGLHADLPTGLHVYIIGDPSKINIEYIHRLLNTNVLRSYFEKGVDKELGLVHDLYIPTTLQKAGVCSWSIAKLALRGGFILEGIENEEIKYKKWSQADRFATVIDYLKQENVDPHLIASLWCRTKDQKIKEVLEDRLTTTHIANEKSTPLHLAAESNNFSVVEKLLMDGENIHREDAEGWTPLIAAACQGHVEMVEYLLEKGACVNKTGKTGLNAYCHLLSQIGECSKNPKMESRIIKVEKVLIEKGIDTDLSNGFRWMARRHAERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCI2</accession>
    <name>A0A0C1HCI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KK00240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386401.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72498">
        <property type="protein sequence ID" value="KIC72498"/>
        <property type="gene ID" value="DB41_KK00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="500"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="699" mass="79443" checksum="A626F64AF5DA4BC6" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCI6</accession>
    <name>A0A0C1HCI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_HW00160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385485.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75104">
        <property type="protein sequence ID" value="KIC75104"/>
        <property type="gene ID" value="DB41_HW00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1371"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025758">
        <property type="entry name" value="Fic/DOC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026287">
        <property type="entry name" value="SoFic-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13784">
        <property type="entry name" value="Fic_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038925">
        <property type="entry name" value="AMP-prot_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="126"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="216"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="217"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="254"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR038925-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="385" mass="43511" checksum="CE1361616E352E21" modified="2015-04-01" version="1">MDILQSPAGQIIKSLSGYKAFVPNPLPPPFKWNTQIVSALSRADFLLGKLAREGGKLPNPHLLMRPFITREAVLSSKIEGTQATIGEILAASVGISVQRNPDDLREVQNYIVALDYGIKRLGDLPLSLRLIKEIHHHLMQGVRGAHATPGEFRRSQNWIGTPGGTLNTAKFVPPPPDHLMDCLGEFEKFLHERQLPPLIHTALCHYQFEAIHPFLDGNGRIGRLLIILLLIEQKMLPTPILYLSAFFEATRDEYYKQLYNVSARGTWHEWLIYFLNGIAVQTEDVLSRVERINDLLNKWKMQVASSTSNVPVLIVEHFAVNPYLTTNRIAEELKIAYSTAQRGIQKLEEAKIIKQINSTRRDKIYCAIEILAILEEATKINADFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCK0</accession>
    <name>A0A0C1HCK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HV00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75129">
        <property type="protein sequence ID" value="KIC75129"/>
        <property type="gene ID" value="DB41_HV00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5393" checksum="43D8B0231EC8EC76" modified="2015-04-01" version="1">MPKAIAFPTDAKLYFKSIQALVKMADSSQITLRQTYKKLAKTALCMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCL5</accession>
    <name>A0A0C1HCL5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">truA1</name>
        <name evidence="4" type="synonym">truA</name>
        <name evidence="9" type="ORF">DB41_KJ00130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386376.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72538">
        <property type="protein sequence ID" value="KIC72538"/>
        <property type="gene ID" value="DB41_KJ00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1931"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="9"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="145"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC72538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="249" mass="28121" checksum="0904CDB73BDF9413" modified="2015-04-01" version="1">MKEYNYKMIIAYDGTQYNGWQIQPNGIAIQQKIEETLKIVLRHPTSLIGSGRTDAGVHALGQVANFKTSLRIDPRRFLHSLNGILPRDIRIHSLENVPLNFHARYSAKGKIYHYYLHLKPTLNPFNRLYSLHVGENIDSGSLKEAAQFFIGTHDFTAFANEAHSGVAAHDPIRTLQRLDVVPTEEGLCLEFEAEGFLYKMVRNITGTLLEIACDKRSISSIPEIFASKDRRCAGKSAPPHALFLMKVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD58</accession>
    <name>A0A0C1HD58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HP00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000126">
        <property type="protein sequence ID" value="KIC75349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75349">
        <property type="protein sequence ID" value="KIC75349"/>
        <property type="gene ID" value="DB41_HP00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5376" checksum="121C00DA794423BD" modified="2015-04-01" version="1">MLDSYKEAEQTRFVGEILSNTLIKVGLHTQSSQSYKSTSGDAFMKYGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD65</accession>
    <name>A0A0C1HD65_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HO00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385378.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000125.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75354">
        <property type="protein sequence ID" value="KIC75354"/>
        <property type="gene ID" value="DB41_HO00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="16205" checksum="D7BCAE694BEA9D22" modified="2015-04-01" version="1">MVNTLANNDNNKNAVSSFPTQLAVSSIEQLPDELLLHIFSFLQASDLLEVELTCHQWKNLAEEEILWKSLYQRYFKVSELVGETYKEDYFRMSEADHDWRKVDELLSSLEHGDLQPDEALRFFGWANEIGGEEAFSEDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEM2</accession>
    <name>A0A0C1HEM2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="3">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">ispG</name>
        <name evidence="4" type="ORF">DB41_GZ00530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="3">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IspG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385010.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75889">
        <property type="protein sequence ID" value="KIC75889"/>
        <property type="gene ID" value="DB41_GZ00530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1119"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017178">
        <property type="entry name" value="IspG_atypical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037336">
        <property type="entry name" value="IspG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 3" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="546"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="577"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="638" mass="72190" checksum="5FEEABA298F62BAC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEW5</accession>
    <name>A0A0C1HEW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GS00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000104">
        <property type="protein sequence ID" value="KIC75979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384859.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000104.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75979">
        <property type="protein sequence ID" value="KIC75979"/>
        <property type="gene ID" value="DB41_GS00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="529" mass="60139" checksum="9269B583A3A9BF6F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEX5</accession>
    <name>A0A0C1HEX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JM00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386165.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73253">
        <property type="protein sequence ID" value="KIC73253"/>
        <property type="gene ID" value="DB41_JM00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="14535" checksum="F8CA305EFB3C511F" modified="2015-04-01" version="1">MVNTLTNADINKNGTTISPNDSTVTSIKQLPDELLLHIFSFLQAFDLLEVELACHQWKNLAEDKTLWKNLYPKHLKIYWHEGWESNKKSYFITLHGEREDEKIMAFLGSIKHVHNLELAKYIGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEY6</accession>
    <name>A0A0C1HEY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GR00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75999">
        <property type="protein sequence ID" value="KIC75999"/>
        <property type="gene ID" value="DB41_GR00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1007"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="223" mass="25312" checksum="BFCC6F1BA7FD012F" modified="2015-04-01" version="1">MKKYFITGLAVLLPLTLTLFIVVFVFNRLTDPFAGITKEILRQNHFLEKTPPQLQHLISQVIIVTLIFFSTVFVGMIGRWLIVRYILRFTEKILRRIPFIRSVYNTCKDVIKTLFISEGKSFKQVVMVPYPNATTYCIGLITRENMVGLGSHSDEELVAIFVPCTPNPTSGFLMMFRKNELIYLDMSVEEAFKYVISCGVISVSFNPLLPSADMLSASPSVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGC5</accession>
    <name>A0A0C1HGC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_3</name>
        <name evidence="3" type="ORF">DB41_JA00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000158">
        <property type="protein sequence ID" value="KIC73718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73718">
        <property type="protein sequence ID" value="KIC73718"/>
        <property type="gene ID" value="DB41_JA00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1713"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="615" mass="70076" checksum="CCA54E3B87F0FAAA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGZ3</accession>
    <name>A0A0C1HGZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_FK00010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76579">
        <property type="protein sequence ID" value="KIC76579"/>
        <property type="gene ID" value="DB41_FK00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="34"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="5">
        <location>
            <begin position="132"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="912"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="946"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="988"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1030"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1072"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1114"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1175" mass="133891" checksum="537F6A97E7F29E6B" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHE0</accession>
    <name>A0A0C1HHE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EU00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383962.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000059.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76729">
        <property type="protein sequence ID" value="KIC76729"/>
        <property type="gene ID" value="DB41_EU00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.574"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="195" mass="19442" checksum="B9CE99D2BF41260C" modified="2015-04-01" version="1">MKKVVFGLASNEAQAQRIVSQLLSAGFHNKDISILSPDQNQPTATSNKYGEAVEGDFARTADKDLSSSSTGSKASEMGAVGAAAGGVLGGSLGLLAGIGSLAIPGLGALIAAGPIMAALSGSAVGGGLGLLVGAIVGAGIPENEAKRYEAGLKAGNILISAHADTREEVTRAYEIMKNEGAKDISSTNETSESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHS8</accession>
    <name>A0A0C1HHS8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxA</name>
        <name evidence="6" type="ORF">DB41_EC00170</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383738.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76869">
        <property type="protein sequence ID" value="KIC76869"/>
        <property type="gene ID" value="DB41_EC00170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.445"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="31"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="106" mass="11612" checksum="C00D9741DBD79E23" modified="2015-04-01" version="1">MSEHLKHLDDDNFGTTIATGVTLVDFFADWCGPCKMIAPIIEELAGELAEKATIAKVDIEKAQKVTAQYGVTSIPTLIVFKEGQEIKRFVGVKSKQDLKNAITMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHW0</accession>
    <name>A0A0C1HHW0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rpsG</name>
        <name evidence="8" type="ORF">DB41_DT00080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383652.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76914">
        <property type="protein sequence ID" value="KIC76914"/>
        <property type="gene ID" value="DB41_DT00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.397"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="7">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="157" mass="17922" checksum="F26F39AF08D0A1A0" modified="2015-04-01" version="1">MSRRRRAEKRHIDPEPLYGSTLLAKFINRVMIGGNKSVARRIVYNALEKFAKRIKAENPLEAFEQALENAKPALEVKSRRIGGATYQVPIEIPTNRRIAMAMGWIINHSRAKTGRSMEDGLSTELADCFHNQGTTIKKKDDTHRMAEANKAFAHYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHX0</accession>
    <name>A0A0C1HHX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DS00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76924">
        <property type="protein sequence ID" value="KIC76924"/>
        <property type="gene ID" value="DB41_DS00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5643" checksum="DEE8850D835527F9" modified="2015-04-01" version="1">MLVVLLAQHLQKSLALQARYLRLYRLLKDLNVKILGILFMNFIILKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HI35</accession>
    <name>A0A0C1HI35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ribonucleoside triphosphate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nrdD</name>
        <name evidence="1" type="ORF">DB41_DP00260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383590.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76974">
        <property type="protein sequence ID" value="KIC76974"/>
        <property type="gene ID" value="DB41_DP00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.361"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013345">
        <property type="entry name" value="RTP_Rdtase_AdoCbl-dep"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02505">
        <property type="entry name" value="RTPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="670" mass="76071" checksum="DDA9037CAF29ED99" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIG6</accession>
    <name>A0A0C1HIG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DH00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243765.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77054">
        <property type="protein sequence ID" value="KIC77054"/>
        <property type="gene ID" value="DB41_DH00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="395" mass="46524" checksum="E35F9BABFC9F673B" modified="2015-04-01" version="1">MHIAFLSNYNLYESKRYFCARFAEAFNRLGIETSIIDYHTLQQQRMEFIRASNPQETVFTCSFNSMISEDGKYISDHTGVPHLAFFVDPAYNYRDVLKSKNTIITCVDHGDCEYIYSKNFSKTFFLAHAVERELEPAMNQERPYEVVFLGSCYDHENLRAYWRQTMEKNDIEIIEKAIEIVLSDNKTSVYPAIKKIVQEEACFCENESELEDKIIHYAYYVDNYMRGKDRTELILSIKNAQVHVFGDLCWRREKPILGWEYSLRTMQNVTIHPAVNYEKGLEILKQSKICLNSMPFFKNGTHERIFNGLACGALPITSDNLWIRRNFEHAENILIYSPHKWAEVDTWVEEYLKKPLKRKEVIAKGREKVMKEHTWDVRAQQLFDGFENLPQIEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIP3</accession>
    <name>A0A0C1HIP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DA00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000017">
        <property type="protein sequence ID" value="KIC77119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77119">
        <property type="protein sequence ID" value="KIC77119"/>
        <property type="gene ID" value="DB41_DA00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4006" checksum="58B2CF3F48E0AAA9" modified="2015-04-01" version="1">MEEGSNFAMAGGQLLVSPARGGGQKFMSPGGQFIMSLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIR5</accession>
    <name>A0A0C1HIR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_CX00150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77149">
        <property type="protein sequence ID" value="KIC77149"/>
        <property type="gene ID" value="DB41_CX00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="4">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="91" mass="10822" checksum="1DAA73510F0E6E5B" modified="2015-04-01" version="1">MIVDKKSRKIICTAFCNGKRHDFRLFKESKTHIHSTITLLTDTEYQGLQKIHFKTQMSKKRSKKNPLTQEDRKSNQKLSKERVLNENAIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK37</accession>
    <name>A0A0C1HK37_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_IB00010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74868">
        <property type="protein sequence ID" value="KIC74868"/>
        <property type="gene ID" value="DB41_IB00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="233"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="788"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1066" mass="122388" checksum="FAB22CAD0F3D6515" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK58</accession>
    <name>A0A0C1HK58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metalloprotease</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385703.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74888">
        <property type="protein sequence ID" value="KIC74888"/>
        <property type="gene ID" value="DB41_IB00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16_C" evidence="1">
        <location>
            <begin position="221"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="459" mass="52998" checksum="966D9D09321AAEC0" modified="2015-04-01" version="1">MPGKIYLFFLYILPFFSLKGLENAKSLSFDPENFVQEVVFDGKEASTLPISEWRLKNGMKVILKQTNDEENEISVRLVALGGYGSVEPEDRASAELAASVAMESGIGEWCPDKLAALLYDQSIELNIKIEPFVRSIDASFPPESLEIFFTLVKKIFQQSRCTPEAFNQVLKSKKDELTRRGREVDSDRLLKVIAVHEQHALNPLNFTDLKKARVSQSERFFRAAFSNPADFVCIIVGKVNPEKIKKLCSDSFSALNVQKVDQKFILPHYKKAPKVRMTKIHHLPHSQESLVYLSLPLHLCLDPTRLEHLELACQMIETRLRNHIKTYSSESRGMDVRYELPLYPSLEYPWITVQFHVDDKQINSTLDLALQQIKTICREGFSLDEVTAASQLKQKRAKLWECSHDYWIILLSNHYLWKWDSKKIVGRFQMPQVIDPKEIHFTLCHSLLMDEYTPLYLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HN36</accession>
    <name>A0A0C1HN36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75753">
        <property type="protein sequence ID" value="KIC75753"/>
        <property type="gene ID" value="DB41_HG00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="11246" checksum="30ED024757A6FBBD" modified="2015-04-01" version="1">MLSSALEASKKGLFKFLQKFYKFIFLIGKQLKELPMRLAKAIFRSYLFACNSFVQINHLMRWFFILSYVLVRLAWQELREIAGHILESYSFKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNH1</accession>
    <name>A0A0C1HNH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative NADH2 dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ndh</name>
        <name evidence="4" type="ORF">DB41_GZ00220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75858">
        <property type="protein sequence ID" value="KIC75858"/>
        <property type="gene ID" value="DB41_GZ00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1087"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="25"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="252" mass="28313" checksum="89B3650F9A626E13" modified="2015-04-01" version="1">MAGAIAEIAHTSLIHNFRHINPEQARIYLIEGSEQILSSFPKDLAEKAARDLRKLGVEIILKTRVTEITSEGVRIGDKFIDSRNVIWAAGNQTSPLLDTLEVMQDHSGRIHVNNDLSVPGYPEIFVIGDAALLLDAAGLPLPGIAPVAIQQSHYVARLIRKNTCGKQRKPFRYFDKGMMATIGKAKAVAVVGKLKISGFIAWLAWCFIHIHFLISFANRVVVMLNWFYLYCRNQRCIRLITRPLTDKDEPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HP61</accession>
    <name>A0A0C1HP61_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GO00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000100">
        <property type="protein sequence ID" value="KIC76053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76053">
        <property type="protein sequence ID" value="KIC76053"/>
        <property type="gene ID" value="DB41_GO00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.988"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="173"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="541" mass="61394" checksum="DA0CAF572D583E6A" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT47</accession>
    <name>A0A0C1HT47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chaperone protein htpG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">htpG</name>
        <name evidence="6" type="ORF">DB41_CO00120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383105.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77243">
        <property type="protein sequence ID" value="KIC77243"/>
        <property type="gene ID" value="DB41_CO00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.46"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="5">
        <location>
            <begin position="28"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="618" mass="71778" checksum="9E15BFB8271ACD89" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT66</accession>
    <name>A0A0C1HT66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CO00320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77263">
        <property type="protein sequence ID" value="KIC77263"/>
        <property type="gene ID" value="DB41_CO00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6604" checksum="0E590486D4E8C4F4" modified="2015-04-01" version="1">MRKESNGIAAENTIKKMSQAKNNRGKKYGLSKKKYTLRIIFQLLCTQGELVMRIIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT87</accession>
    <name>A0A0C1HT87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CK00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383065.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77288">
        <property type="protein sequence ID" value="KIC77288"/>
        <property type="gene ID" value="DB41_CK00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="346" mass="40025" checksum="C4E2FCE7EC52C5CD" modified="2015-04-01" version="1">MKAWFFLWVLLGLFSPFVQGIADEKEFEVVITPAASTISINDFLTVHLRLTFPAGYQVDLKKLHQNLLRSSSFYEHPFTLVEMKIENLQEHAKGRFSQEIVLILQPRRLGELFLTFYDIDFIAENKSAPIKKIVSELYPIKVTAPKITSQIPENFAALLTFEKKLPMELSEENQKLLLNDPSLQKQEIERNIKQMHEKQLPWIQIGCFALITLYLCFFLKSFSIKKPLTSKQLAKIAKKSALAELRQLRSKQLPAKGLFDNFYVHLTDTLRAYIQKKYHIPAATSTTPEFLAEVAQSSVFSSSFRQQLVHFLQQADRVKFERYSPSIEECEIAYQLAIQFIQDDPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJR2</accession>
    <name>A0A0C1JJR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Low calcium response locus protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lcrH_2</name>
        <name evidence="5" type="ORF">DB41_AV00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LcrH/SycD chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386890.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71570">
        <property type="protein sequence ID" value="KIC71570"/>
        <property type="gene ID" value="DB41_AV00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005415">
        <property type="entry name" value="T3SS_Ca_resp_chp_LcrH/SycD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011716">
        <property type="entry name" value="TPR-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07720">
        <property type="entry name" value="TPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01595">
        <property type="entry name" value="SYCDCHAPRONE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02552">
        <property type="entry name" value="LcrH_SycD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC71570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="184" mass="21153" checksum="9CA6C9B5E81253F1" modified="2015-04-01" version="1">MKSDEEQIKKAVESLGEQLKNDASQEKNVTQLADEFFKNGHMPKDLLNLSDQQVEGLYAQGYNFYQTGRYKDAVQVFRLLIMLNANEAKYILGLASCFHMMKEYKNAVDTYTICCVLDPENPIPYYHMSDCFVAMKDSYSTIIALEMAIKRAGSKPEFQMLKDRALLTIKHLQEEIKDTIKAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKR0</accession>
    <name>A0A0C1JKR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CG00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000252">
        <property type="protein sequence ID" value="KIC71146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71146">
        <property type="protein sequence ID" value="KIC71146"/>
        <property type="gene ID" value="DB41_CG00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4891" checksum="B74CF409165AA543" modified="2015-04-01" version="1">MDKVIEVLKDKLTMEQEVRLAKEKAKEKHKSTDSLTNLFMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL55</accession>
    <name>A0A0C1JL55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72020">
        <property type="protein sequence ID" value="KIC72020"/>
        <property type="gene ID" value="DB41_AA00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5243" checksum="B2B526C83B53E25B" modified="2015-04-01" version="1">MANRTTFLNSALATNSIKIILLFKLSKLIGWKQLEEEFDKLFVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL61</accession>
    <name>A0A0C1JL61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BN00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000234">
        <property type="protein sequence ID" value="KIC71326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71326">
        <property type="protein sequence ID" value="KIC71326"/>
        <property type="gene ID" value="DB41_BN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5454" checksum="DFFF9CEB710D7BED" modified="2015-04-01" version="1">MRQKEPFFSNKAKDQSHSYNQIKIAALLNPQNLWLLLNAWKAPPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPN9</accession>
    <name>A0A0C1JPN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386400.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72496">
        <property type="protein sequence ID" value="KIC72496"/>
        <property type="gene ID" value="DB41_KK00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="15124" checksum="48FF73DF1D61E097" modified="2015-04-01" version="1">MNPIMREIKQDFIKPAFEKEALQAAARECGYDISLTISPTEKEILINHFVKSLLKKIEDHYQKNSEFASISVNLPKNVEKITRKKFEKKNICTVSDNPRNFHDQSLEDFFPMFDSVLNYLKTWGRYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPS6</accession>
    <name>A0A0C1JPS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KJ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386361.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000190.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72526">
        <property type="protein sequence ID" value="KIC72526"/>
        <property type="gene ID" value="DB41_KJ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="270"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="38175" checksum="1F5030B69C03374C" modified="2015-04-01" version="1">MTSVLNSKIVSMLENPRLAENQKGNLNGRKTLPLPYYLLKSGAVIGGVATVACGVAAIGFSTLPMLVAALACGLVCLSSAVGSFYIERLSHPNKSHPLINPQLPERTHNYNKIDEYLKNANENLLKAENNIEKHTSEINVLHAQLRLKEAEIEDKNKMIKSYLKTLEEGRKNVEKDLQTIVLFLKEKGENEVQVQQVLSLLNHMRSLARRQEKEEESSDYDNLLKDYLDLNARLLSILSILPHCFDKYRVQMKTESNLEGGTVKGVINVKDNRELEIQNLKSEVKRLKEELEKQYAHYQFIDQIIDQKQELEKTNLSKSQESSNLSHSFIVVEPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQP6</accession>
    <name>A0A0C1JQP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KA00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000183">
        <property type="protein sequence ID" value="KIC72841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386263.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000183.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72841">
        <property type="protein sequence ID" value="KIC72841"/>
        <property type="gene ID" value="DB41_KA00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="14527" checksum="27B22FA499B31331" modified="2015-04-01" version="1">MNYIFSLFTSCGAHSYQEYEVLEKKDEDRGIEELRQWIETHPVTSSIKMLESAKKLDKYTNELMKSLKEVPLTTSNVDLLKDHLVLLAKQNDSVRRRLIDKISNLKGEKSLLEDLQVKLIFTCAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRK1</accession>
    <name>A0A0C1JRK1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">plsX</name>
        <name evidence="5" type="ORF">DB41_IY00060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73810">
        <property type="protein sequence ID" value="KIC73810"/>
        <property type="gene ID" value="DB41_IY00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1699"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC73810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="36922" checksum="5C149A6926895A05" modified="2015-04-01" version="1">MRIGIDLMGSDSSPTIIFDALIQALDQLDPSLRLIALATQSVIDEHRAKAKISLPAEKFNRLTFLPVANFIEMGEDPLIALRQKKRSSTAVGIKLLKKKQIDALVSAGNTGALVASATLSLPKLPGITRPALLATLPTKNGSLAIVDVGGNVSCKAEHLVKYAYMGAAYQKCTSGIKIPKIGLLNIGSESKKGTSVVRKAYQLLKDVCQHSIDGVPYMEFHGNIEGREVFYGKVDVLVTDGFTGNILVKTSEGLADFIFEYLRETRQDHPLNFLQEPLEYLQALFYYAEYQGALLCGVEGLVIKCHGHSNTKAFFNSIKGVSHMIKNNLLMQIRDALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTW0</accession>
    <name>A0A0C1JTW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IJ00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243988.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74540">
        <property type="protein sequence ID" value="KIC74540"/>
        <property type="gene ID" value="DB41_IJ00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1590"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="339" mass="38746" checksum="524A14800285A25E" modified="2015-04-01" version="1">MIELKDEKAQLAIKNLIEMCGQPSDTFEAELVTQMIETSLKLLIENNDTGQLKLINRSLKEMRHAYRIFSKFKQSRCISIFGSARTPENHPDYFAAKSFSTQIAELGWMCITGGADGIMKAGLEGSQKKSSFGLSIRLPFEAPTNTVIAGDPKLIVFRYFFIRKLMFLTHSDAVAVFPGGFGTMDELFELLTLMQTGKANLMPLVLVESKNGVYWPHWKMNIDEHLLANGWISPEDLNLFYIARSVEDAVLHVQQFYRHYHSSRYVGSQLVIRLNRELTDREVEHLNKHYQLLAAEGKIEKSGPLPQEIDHLNLPRLVFQHTHRDFGILRAMIDTLNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUU4</accession>
    <name>A0A0C1JUU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IC00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000137">
        <property type="protein sequence ID" value="KIC74850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74850">
        <property type="protein sequence ID" value="KIC74850"/>
        <property type="gene ID" value="DB41_IC00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1542"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="184" mass="20754" checksum="CC0BF1EEC79BC755" modified="2015-04-01" version="1" fragment="single">QGLDLSQNQLTSLPGEIGQLSQLQGLDLSQNQLTSLPTEIGQLSQLQELELSQNQLTSLPTEIGQLPQLQWLYLNQNQLTSLPTEIGQLPQLQWLYLNQNQLTSLPAEIGRLSRLQELDLSQNQLTSLPAEIGRLSQLLRLDINQNQLISLPVEIGQLSQLLILELAENPLKDIPEKIRRRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV03</accession>
    <name>A0A0C1JV03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385711.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74895">
        <property type="protein sequence ID" value="KIC74895"/>
        <property type="gene ID" value="DB41_IB00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="10643" checksum="DB60533E6006E56E" modified="2015-04-01" version="1">MDEVINEIDAEEEVEGRTLALDLLSQVAEGALAPFEATIHLKDHILKIFERIKNGVIEAMGGIQKSNKPTPFRLLKIFWNEGTLNPYKPDLKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV17</accession>
    <name>A0A0C1JV17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative serpin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385728.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74915">
        <property type="protein sequence ID" value="KIC74915"/>
        <property type="gene ID" value="DB41_IB00480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SERPIN" evidence="2">
        <location>
            <begin position="52"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="422" mass="47997" checksum="062FA9DE87D4A297" modified="2015-04-01" version="1">MKHIFTKTWFKLVVLGWISLFSLPIQSEEEKTSHDELNERLLVSQGANAFAVDMYNQLPSTNNLCFSPYSIFSSFAMAYTGADENTHKEISAALHYPPSVDKLGKGLAELNHFFTFYPSSASDEIRVRVANSLWIQTNFPLLPSYKENMKKYFNGTFRVIDFKGQPETARATINAWVKHHTFGKIIDILHSQAIDSSTRMVLVSALYLKAKWKNPFDPHLTTQQPFFTEDGVVQTALSMTQTAYLPYLDTPEATVVELPYILSRKEGPEFSMMIILPHQKEALREVEKGLTVRKLEEWRKNLENTKVLITIPKFKVLQSSNLKDILEKMGMHTPFSEQANFSKISEFKGLKIGNVLHKVYLSMDENGSEVAAATSISMNVTSILEPKAPVIFQVDHPFIYMIYEKKTGTILFMGRVTDPNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV52</accession>
    <name>A0A0C1JV52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 16" type="primary">dnaG</name>
        <name evidence="16" type="ORF">DB41_IB00780</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385763.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74945">
        <property type="protein sequence ID" value="KIC74945"/>
        <property type="gene ID" value="DB41_IB00780"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1514"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="259"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KIC74945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="595" mass="68246" checksum="BBEE2F9AA76A0D95" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JW87</accession>
    <name>A0A0C1JW87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HO00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385386.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000125.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75360">
        <property type="protein sequence ID" value="KIC75360"/>
        <property type="gene ID" value="DB41_HO00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="8487" checksum="68214360AD33B57C" modified="2015-04-01" version="1">MATTNHANNKANSFPIPSLLKSELPSPLAPEENHVSSSPVTKSISSAVEAKQMLPSASNQKILTAEGWKRMMLRDKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWC0</accession>
    <name>A0A0C1JWC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HM00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000123">
        <property type="protein sequence ID" value="KIC75390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385338.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000123.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75390">
        <property type="protein sequence ID" value="KIC75390"/>
        <property type="gene ID" value="DB41_HM00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="DUF917"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="DUF917_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="DUF917_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="DUF917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="364" mass="39416" checksum="1D3BAB91ADF44E19" modified="2015-04-01" version="1">MKKLTLQNLDDLAIGSAILGSGGGGDSTYAYMMARYEMEKKASLSILNYADLKPEALVIPIGFMGAPTVEMEKIVTGRDYVELFKIVEKNLNKKITAIMPFEIGGHNAFTPIITGLQMGLPVLDADMMGRAFPEAQMSSGHLYGVSPNPGFISDSLDNAVVIHAKNTFALEKIGRSATIAMGSIAAFAFYPITGAKARECTVPNSISRAINLGKAHRSAKEKGEDPLEAILNHCKGILIGSGKITDIDREISKGFLQGSITIQNSKDKIELIFQNEYLLAKINSKIIATTPDILMLLEQETGAPITSELLQYGLRVNLIALPAPEIWTTPQGLALVGPRKFGYETDYKPIHKARQKSSVLSITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX26</accession>
    <name>A0A0C1JX26_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Acyl carrier protein</fullName>
            <shortName evidence="1">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 5" type="primary">acpP</name>
        <name evidence="5" type="ORF">DB41_HJ00050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75605">
        <property type="protein sequence ID" value="KIC75605"/>
        <property type="gene ID" value="DB41_HJ00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1248"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 2 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1 2">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="79" mass="9118" checksum="E6B2952929DBA46B" modified="2015-04-01" version="1">MSSTEQEVIDIIVEQLGVDRDDVTPSKKLVEDLNADSLDLTELNMTFEERLGREIPQEEAEKFKTVGDIIQYFDRITKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXD4</accession>
    <name>A0A0C1JXD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HH00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385225.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75730">
        <property type="protein sequence ID" value="KIC75730"/>
        <property type="gene ID" value="DB41_HH00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="9056" checksum="AF04DCC1292C7729" modified="2015-04-01" version="1">MTTEEFPLSSQDLMIEFAELMTETLLKREVHHADPFEVYAHRLRSHFYNCPERFKRHFAEGYCLLVKELEKESIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXI1</accession>
    <name>A0A0C1JXI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HE00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75785">
        <property type="protein sequence ID" value="KIC75785"/>
        <property type="gene ID" value="DB41_HE00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4664" checksum="E2FADA355EE9FED8" modified="2015-04-01" version="1" fragment="single">MPGRFEGLTDAQWRILQPLLPQNPPKNLKGKPHTPWRKIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXJ0</accession>
    <name>A0A0C1JXJ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SpoIID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HW00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385477.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75096">
        <property type="protein sequence ID" value="KIC75096"/>
        <property type="gene ID" value="DB41_HW00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134918" description="SpoIID domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="SpoIID" evidence="2">
        <location>
            <begin position="131"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="280" mass="30872" checksum="CAA031EBBE34F982" modified="2015-04-01" version="1">MIKKMFIAFLGFILLSNAAHAGIADSLSTFFNKPLPAAKDTLKILITHNKPGAMLEVKGKYKIYDPHTNKHISTRFIGKKKYIQPLSEGLKWQEEFPGLYQLMILPDDKATTIIVDGIEYKGRIYIYDIGGTISIVNEIPFDEYVKTILAARLQAPLPGEALAAVAIAARTNAYYLKQKAPSDYWDVEAKQIGYQGYALSPPSKLIEQAVKATHHMVMTFSSSPLMAKWDSIEAIDGGQAQVTHSKISLDQAAMLAHQGEHAAQILKKAFPGAQIDLIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY07</accession>
    <name>A0A0C1JY07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="1">6.3.4.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Queuosine biosynthesis protein QueC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">queC_2</name>
        <name evidence="1" type="synonym">queC</name>
        <name evidence="2" type="ORF">DB41_HQ00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27982"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the QueC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000127">
        <property type="protein sequence ID" value="KIC75341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385413.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000127.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75341">
        <property type="protein sequence ID" value="KIC75341"/>
        <property type="gene ID" value="DB41_HQ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1322"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01633">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="219" mass="24075" checksum="C992788DFF877B3F" modified="2015-04-01" version="1">MKKAIVLLSGGLDSTVILALSLAQGRECYALSFDYGQRHRIELTHASKIATYYQVKHCIVKIDSKVFKSSSLVSDLALPKNRSKEDIGSGKTPNTYVPARNTLFLAYAMGQAEILDAQEIYLGANALDAPSYPDCTLSYIQAFQRVLNVGTKQAAEGNAPQLLTPLIHWDKAEIIRQGIALNVPMHMTFSCYDPTPQQKPCGQCDACILRAYGFTVAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY49</accession>
    <name>A0A0C1JY49_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HN00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385363.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75386">
        <property type="protein sequence ID" value="KIC75386"/>
        <property type="gene ID" value="DB41_HN00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="16060" checksum="DAC1C7926DF07CED" modified="2015-04-01" version="1">MVNTLTNNDNNKNVASSSPTQLAVSSIEQLPDELLLHIFSFLQASDLLEVELTCHQWKNLAEEEILWKSLYQQYFKMIEPVGETYKEDYFRMSKADHQWRKVDELLSSLEHGDLRPDEALRFFGLANEIGGEAALPDDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYI7</accession>
    <name>A0A0C1JYI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_KQ00220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244070.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72257">
        <property type="protein sequence ID" value="KIC72257"/>
        <property type="gene ID" value="DB41_KQ00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2029"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="28"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="753" mass="85101" checksum="7DA0C8170DA84C65" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ56</accession>
    <name>A0A0C1JZ56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76300">
        <property type="protein sequence ID" value="KIC76300"/>
        <property type="gene ID" value="DB41_GK00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4939" checksum="46C18A8A09450582" modified="2015-04-01" version="1">MINKAFLNTKHSHQQRTEFFFKAQSKYSQEQGYYLLYQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZH1</accession>
    <name>A0A0C1JZH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Low calcium response locus protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lcrD</name>
        <name evidence="11" type="ORF">DB41_GZ00400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384992.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75876">
        <property type="protein sequence ID" value="KIC75876"/>
        <property type="gene ID" value="DB41_GZ00400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1105"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025505">
        <property type="entry name" value="FHIPEP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006302">
        <property type="entry name" value="T3SS_HrcV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01399">
        <property type="entry name" value="hrcV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00994">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC75876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="726" mass="79231" checksum="EA0143F1E30E0213" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZT3</accession>
    <name>A0A0C1JZT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GA00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76480">
        <property type="protein sequence ID" value="KIC76480"/>
        <property type="gene ID" value="DB41_GA00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="5880" checksum="53844D83199B9181" modified="2015-04-01" version="1">MPAACFFSFTFISIIDFFAIKRALSGKAAVASLPAKSPPIFIGCFYSSSTVLVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K026</accession>
    <name>A0A0C1K026_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76560">
        <property type="protein sequence ID" value="KIC76560"/>
        <property type="gene ID" value="DB41_FN00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4580" checksum="E3B999B127FB8DB9" modified="2015-04-01" version="1">MLQSCRNVPEIEKGYEKVIENMQDLLELFLSVVVLNKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K046</accession>
    <name>A0A0C1K046_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">ftsH</name>
        <name evidence="9" type="ORF">DB41_FM00080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000074">
        <property type="protein sequence ID" value="KIC76575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384277.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76575">
        <property type="protein sequence ID" value="KIC76575"/>
        <property type="gene ID" value="DB41_FM00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.724"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="459"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="882"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="907"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="689"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="466"/>
            <end position="473"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="688"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="692"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="764"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC76575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="921" mass="102815" checksum="56B4A711EDDA21CD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0A8</accession>
    <name>A0A0C1K0A8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein SHOC-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">shoC2_2</name>
        <name evidence="3" type="ORF">DB41_FI00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243840.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76600">
        <property type="protein sequence ID" value="KIC76600"/>
        <property type="gene ID" value="DB41_FI00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.683"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="30"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="17"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="922" mass="103939" checksum="7F620535EDDBC290" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0F3</accession>
    <name>A0A0C1K0F3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acriflavine resistance protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">acrE</name>
        <name evidence="3" type="ORF">DB41_FD00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76645">
        <property type="protein sequence ID" value="KIC76645"/>
        <property type="gene ID" value="DB41_FD00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="59"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="392" mass="43125" checksum="B5164189D7E3888B" modified="2015-04-01" version="1">MMKVDFLRPFLLIALVFLLAASCGGEKSLPPPPFVEVSALTIQKDTIPWIYESVGYAESSHQVEIRARVEGYLEEIAYIEGAQVTKGQLLFKLDQTPFIAAVEQAKGNLAREKALLWNAQQTVERLTPLYAKHAVSKKDLDEATANLLASQASVQVAEAALKVAEINLSYTLLTSPINGLSGKSSYRQGALISPGSNQLMTSITALDPIWISFSISENEILKIDKEVKNRTLVLPKDKNYGVEVILADGSRYPSRGEVNFSAPAYDQKTGTLSMRAQLPNPNLILKPGQFVRVNVKGAIKPNTIYVPQKALLESKTGMYVYIVREGKAAIQNVIVGDWYGDYWIIEEGLREGDQVIVDGINKVGQGSPIKVTKEIKVDKSHKQELILPQLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0V8</accession>
    <name>A0A0C1K0V8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_EJ00150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76785">
        <property type="protein sequence ID" value="KIC76785"/>
        <property type="gene ID" value="DB41_EJ00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="238"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="327" mass="36499" checksum="DD096BFDBE47103B" modified="2015-04-01" version="1" fragment="single">HLDKAEEYSTKALVIDLKLSGEDHPSVAIDYNNLGGIYKEQGNLGKAEEYSTKALAINLKLFGEDHLTVANIYNNLGKIYKKQSYLDKAAEYINKVLAINLKLFGEYHLEVAICYNNLGLIYQDQGNLSQAEECSSKALAINLKLFGEYHSSVAFGYNNLGLIYKNQGYLGQAEECSSKALAINLKLFGESYPDVASNYSSLGLIYKEQGNLDKAAEYINRALVINLKLFGENHHTVVRDYNNLGQIYQDQGNLEKAAKYINKALAIDLRLFGEHHSTVATHYNNLGLIYKKQGNLDKAAVYINEALAIDFKFLAKITPQWQSTTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K159</accession>
    <name>A0A0C1K159_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal small subunit Rsm22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_JQ00080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000173">
        <property type="protein sequence ID" value="KIC73157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386194.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000173.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73157">
        <property type="protein sequence ID" value="KIC73157"/>
        <property type="gene ID" value="DB41_JQ00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1806"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC73157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="327" mass="37519" checksum="6982B58AC33025B4" modified="2015-04-01" version="1">MNLPNILQQALEREARTLRGSALQQATQELSERYRNEKQRQKIMQSKQHFVSSPEQRIAYLLSRMPATFEAIRYVLNKLKERYEGIFGSVLDVGAGPGTAMWAVSELFPHTCKITLLEQDNFLISLGKKLTLQAKTSLFREAQWVEGDVLKQDCFPESDLIIVSYAMGEWPKPVWGEIIKKLWKSARQALVIIEPGTMLGFQVIRQIRQHLIDLQAHVLAPCPHQHACPMAEKDWCHFSVRLERSPFHKQAKGALLGYEDEKFSYIICTKAATALPEARILRHPHKHSGHLSFKLCTQNEGLADRIISRRHGELYKKARNLEWGDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K183</accession>
    <name>A0A0C1K183_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS4 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FU00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76516">
        <property type="protein sequence ID" value="KIC76516"/>
        <property type="gene ID" value="DB41_FU00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.759"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039365">
        <property type="entry name" value="IS701-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33627">
        <property type="entry name" value="PTHR33627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_5" evidence="1">
        <location>
            <begin position="21"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="224" mass="25771" checksum="D7483D396F44B170" modified="2015-04-01" version="1">MELKAINQTIKQKKEELALFLRPFFSREEARQVALQYTWGLMSKAERKNTWQLAEEAGLQAPYAFQHLLRRGLWQADAIRDRLQMEVLKDKEGGMLAIDETGFLKKGKHSAGVAKQYSGTAGRIENCQVGVFLSYATNQGQVLIDRELYIPEEWFLDEERRARAGISKEVKFKTKIQLAMLMLQRAFGHGIRPSLSNGRRDIWSLSLKSLSRERMLSLYISCTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1A7</accession>
    <name>A0A0C1K1A7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FU00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76531">
        <property type="protein sequence ID" value="KIC76531"/>
        <property type="gene ID" value="DB41_FU00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4998" checksum="7026BD3293A10674" modified="2015-04-01" version="1">MRKKTDKEFIRGKQSIEWTFQKAANDNNHYFCFLNFQAVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1G8</accession>
    <name>A0A0C1K1G8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="6">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgP</name>
        <name evidence="7" type="ORF">DB41_DQ00090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000033">
        <property type="protein sequence ID" value="KIC76945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383596.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76945">
        <property type="protein sequence ID" value="KIC76945"/>
        <property type="gene ID" value="DB41_DQ00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.371"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102250">
        <property type="term" value="F:linear malto-oligosaccharide phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102499">
        <property type="term" value="F:SHG alpha-glucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="PTHR11468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="852" mass="98216" checksum="10218DCFDCF3DCB6" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1T6</accession>
    <name>A0A0C1K1T6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transposase for insertion sequence element IS702</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DN00360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC77015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77015">
        <property type="protein sequence ID" value="KIC77015"/>
        <property type="gene ID" value="DB41_DN00360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.329"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027805">
        <property type="entry name" value="Transposase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13613">
        <property type="entry name" value="HTH_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_4" evidence="1">
        <location>
            <begin position="48"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="145" mass="17069" checksum="D1CDD83C448E0617" modified="2015-04-01" version="1">MKFDKIEKLDDERFRRLTGVKRGTFDKMVQILQQADAAKKIKGGRKYKLRLEDMLLMTLEYIREYRTYFHISQSYGISESSAYKAVKWIEDTLIKHPDFALPGRKELLKNDTEYEVILVDATETPIERPKKNKSAIIQGKRKNIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1V1</accession>
    <name>A0A0C1K1V1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DL00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77025">
        <property type="protein sequence ID" value="KIC77025"/>
        <property type="gene ID" value="DB41_DL00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="73" mass="8426" checksum="54A06E1524BF115F" modified="2015-04-01" version="1">MAIDMAFEEHKRLKAMTAFIGFTLKDPVLSCLREHLLDEPYHENLKAFKEADKGKGLICCKDFHDFIDKLGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K271</accession>
    <name>A0A0C1K271_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_EJ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76771">
        <property type="protein sequence ID" value="KIC76771"/>
        <property type="gene ID" value="DB41_EJ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="17455" checksum="5782978FC33C2648" modified="2015-04-01" version="1">MIDWDVHHGNGIQDIFYEDPAVFYFSTHNKRIYPGTGSSQEKGRGAGKGSNLNFPIEPYENPRKKIKEIFSGQLMESMKSFQPEFIFIAAGFHAHAQDPIGGFNLTTHDFVDLTRNVKGLAEKYCKGRLVSVLEGGYNLEVLKEIIPAHVQGLLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2M7</accession>
    <name>A0A0C1K2M7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CO00340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383134.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77265">
        <property type="protein sequence ID" value="KIC77265"/>
        <property type="gene ID" value="DB41_CO00340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="629" mass="72209" checksum="F18F547C08E96904" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2V4</accession>
    <name>A0A0C1K2V4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">mRNA interferase YafQ</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yafQ</name>
        <name evidence="3" type="ORF">DB41_DK00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000027">
        <property type="protein sequence ID" value="KIC77036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383456.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77036">
        <property type="protein sequence ID" value="KIC77036"/>
        <property type="gene ID" value="DB41_DK00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.265"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40588">
        <property type="entry name" value="PTHR40588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006156">
        <property type="entry name" value="YafQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="10372" checksum="4DFA1AA9B7B8C8F4" modified="2015-04-01" version="1">MLKPIHLRLFEKEVVKAKKRGKDIEKLKEVMKLLTLDGPLPPKNRNHKLKGDYVGYWECHIEPDWLLVYKKTETEIIFARAGSHSDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2W8</accession>
    <name>A0A0C1K2W8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DI00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383439.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77046">
        <property type="protein sequence ID" value="KIC77046"/>
        <property type="gene ID" value="DB41_DI00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046153">
        <property type="entry name" value="DUF6155"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19652">
        <property type="entry name" value="DUF6155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="174" mass="20608" checksum="4DAAECB5F26B23DA" modified="2015-04-01" version="1">MTIKKLKEHLQKQDQDSLLDEILTLYKTFDFVREYYDSRLEPHAPSDIAQKYKKILEEQFCPKKGFPELKYSVARKAISDFKKVCADYLSILDLQLTYVEYGVKCTLDYGDIDERFYNSMESMFEKTLKDMEEYGVLENFQKRCLNIHVQTQDMGWGFGDAIEGLYKDFFEKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K324</accession>
    <name>A0A0C1K324_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IZ00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000157">
        <property type="protein sequence ID" value="KIC73737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73737">
        <property type="protein sequence ID" value="KIC73737"/>
        <property type="gene ID" value="DB41_IZ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="571" mass="65244" checksum="93E85822DA92C7EF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K372</accession>
    <name>A0A0C1K372_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CU00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000011">
        <property type="protein sequence ID" value="KIC77181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77181">
        <property type="protein sequence ID" value="KIC77181"/>
        <property type="gene ID" value="DB41_CU00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5260" checksum="9CF3A3329F233AFE" modified="2015-04-01" version="1">MFNGDRSSRIYCRASLKFVHIFAFLASMYIREKQKMQENAIDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5T9</accession>
    <name>A0A0C1K5T9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="9">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">gmhA</name>
        <name evidence="11" type="ORF">DB41_II00120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385907.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000142.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74627">
        <property type="protein sequence ID" value="KIC74627"/>
        <property type="gene ID" value="DB41_II00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1577"/>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="36"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="51"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="92"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC74627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="199" mass="21375" checksum="47CCB48F96BE410F" modified="2015-04-01" version="1">MSNSKVLTAIRQSIQAVEKLLLPHNQAFLQQAASLIAECFSRGNKLIIAGNGGSLCDAAHFAEELTGVFRQTRPALPALVLSEPGHLTCVGNDLGYENIFSRGIEALGKPGDIFVGLTTSGNSLNIVKAFEAARLYQMQIIAFLGKTGGRLKGMADLEMVIDGFETSDRIQEAHMAAIHIIIELVENRLFYSSASALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6M7</accession>
    <name>A0A0C1K6M7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RCK N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74897">
        <property type="protein sequence ID" value="KIC74897"/>
        <property type="gene ID" value="DB41_IB00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="14"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="146" mass="16608" checksum="81714B77CF7402DB" modified="2015-04-01" version="1">MYKNVDLQQSFLPRALVIGYGPVGRAVTHYLKESNFHPLVIDRNIDTVAAMKEKGIEAIFGDATQFQILEKADLTNLQLMVVTTPDLHITQSIIQVAYHINPYIKIIARSHYKVDHQFLKFAEVPMVWDEEAAAEKMVSLLRTQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6X8</accession>
    <name>A0A0C1K6X8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2760 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HY00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385549.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74987">
        <property type="protein sequence ID" value="KIC74987"/>
        <property type="gene ID" value="DB41_HY00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1408"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021212">
        <property type="entry name" value="DUF2760"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10816">
        <property type="entry name" value="DUF2760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2760" evidence="1">
        <location>
            <begin position="39"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="162" mass="18140" checksum="6E50031E04152C54" modified="2015-04-01" version="1">MRFLLAIKAFIKAWKEPTKALVFLDDSVKNLDSTKQDYSHLRLLALLQQSGRLIDFLKEDIHAFTDAQVGAAVRQIHQECSKNLEELVTIRPIMLEKEGAMVTVPKGYDTTAIKVSGQVKGEPPYIGTIVHQGWKAHKRSLPMKMAEQASEIICPAEIEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K703</accession>
    <name>A0A0C1K703_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HY00330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75007">
        <property type="protein sequence ID" value="KIC75007"/>
        <property type="gene ID" value="DB41_HY00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="8268" checksum="0BD559DF29FD446F" modified="2015-04-01" version="1">MCAWRTTKTLDKNSLLETKQGKIKFFIKAIIVVNKLLSQAIFVLCYWLFYTTTVLSKGLYKRVVKCRLGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7Q4</accession>
    <name>A0A0C1K7Q4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HT00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000130">
        <property type="protein sequence ID" value="KIC75197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385442.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000130.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75197">
        <property type="protein sequence ID" value="KIC75197"/>
        <property type="gene ID" value="DB41_HT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1344" mass="155832" checksum="94D5DF6536E4BD36" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K8E1</accession>
    <name>A0A0C1K8E1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HL00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385328.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75477">
        <property type="protein sequence ID" value="KIC75477"/>
        <property type="gene ID" value="DB41_HL00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="187" mass="21704" checksum="8828F0563683DFA2" modified="2015-04-01" version="1">MHIIDTIGFLVSVAAMLYMLIKLVQPNKRSKKLASIQDDDPLQAKRLQDFLHSLNADMEKSKNFTPPSPKNLKPASLPPEHKKKTIYHQPAYKKKTSKEENKFKSNLDGFQVRNQIEERQFNMNSKNKYEGDYGDHLLSQGFRENKSAPPLIYKRSSRIKNLIHHLPTKKDLIVIHEVLNPPKGFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K8Z4</accession>
    <name>A0A0C1K8Z4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fabD</name>
        <name evidence="6" type="ORF">DB41_HJ00070</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385301.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000120.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75607">
        <property type="protein sequence ID" value="KIC75607"/>
        <property type="gene ID" value="DB41_HJ00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1250"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="5">
        <location>
            <begin position="10"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="313" mass="34651" checksum="2F44CFD6389CC2EC" modified="2015-04-01" version="1">MSHFKKIAFLFPGQGVQYLGMAKDIYENFSIARQTFQEADEVLHRHLSKIILEGPEEELLETKNSQVGIYVVSMALLRIIKDLYPNIQPDMCAGLSLGEYSALTASKKLDFASCLSIIQYRGHYMNEACEAHPGGMAVVLGLTAHEVEEAVQAVNLPHDLWIANFNCPGQIVISGTRKGIDSAASALKDKGAKRVLPLNVYGAFHSGLMKTAEERLAEHIHYASIQDSPIGLIMNVPGKKVENILDIKSHLIRQVTSPVRWEQSIRHLGEEGIELFIEIGCGKTLAGFNKRILPHINTISVEKLTELDQLAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9I1</accession>
    <name>A0A0C1K9I1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GZ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384947.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75837">
        <property type="protein sequence ID" value="KIC75837"/>
        <property type="gene ID" value="DB41_GZ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134571" evidence="1">
        <location>
            <begin position="23"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="9"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="205" mass="24156" checksum="2225D15F6F2753A0" modified="2015-04-01" version="1">MKKFVLLTILFAAFLVPQCVKAVDMEGFYVGATGAANFLQHAKKHRGKFDTGYFGTVDLGYRWCNRFHLEAEVAYRYNKGKKRHHYHNGDLVTNHRHRGHRDTWAAMVNVLYDFDMQWTMAPYVGVGIGYAHIKNERHYNYAGNAHHRYHKNDNQFAWQAVAGVAYPIYYNVDLAVEYRFFDTTTRRHERSNYNHDVGVNLKYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9J9</accession>
    <name>A0A0C1K9J9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyr_redox_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GZ00210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75857">
        <property type="protein sequence ID" value="KIC75857"/>
        <property type="gene ID" value="DB41_GZ00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1086"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="86" mass="9168" checksum="2BE0697D6C82D97F" modified="2015-04-01" version="1">MSKLKVVIVGGGFGGLNAAKALKKAAVDVLLLDKTNHHLFQPLLYQVASAALSPSNIASPIRTIFSKQENVTVLLANITAIDKEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9N3</accession>
    <name>A0A0C1K9N3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transglut_core2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_GZ00460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0162 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75882">
        <property type="protein sequence ID" value="KIC75882"/>
        <property type="gene ID" value="DB41_GZ00460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1112"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transglut_core2" evidence="5">
        <location>
            <begin position="170"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="309"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="520" mass="58862" checksum="344CF8C0CDCFCFC0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA04</accession>
    <name>A0A0C1KA04_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha</fullName>
            <shortName evidence="10">ACCase subunit alpha</shortName>
            <shortName evidence="10">Acetyl-CoA carboxylase carboxyltransferase subunit alpha</shortName>
            <ecNumber evidence="10">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">accA</name>
        <name evidence="13" type="ORF">DB41_GU00160</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AccA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="10"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384883.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75967">
        <property type="protein sequence ID" value="KIC75967"/>
        <property type="gene ID" value="DB41_GU00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1036"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00823">
        <property type="entry name" value="AcetylCoA_CT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001095">
        <property type="entry name" value="Acetyl_CoA_COase_a_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42853">
        <property type="entry name" value="PTHR42853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03255">
        <property type="entry name" value="ACCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01069">
        <property type="entry name" value="ACCCTRFRASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00513">
        <property type="entry name" value="accA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="12">
        <location>
            <begin position="36"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC75967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="319" mass="36229" checksum="EA356C42F7B0EF4A" modified="2015-04-01" version="1">MDILPHERQIQEYVKTIEHLKKQNNDNPIFNTEIKKLEQKLEKLKEKIYAELTPWQRVQICRHPSRPQSSDYIKNICQNFYELCGDRTYGDDPSIIGGLAKIGPMKCMVMGQEKGCDTESRVHRNFGMLNPEGFRKALRLMQLAEKFNLPIVTFLDTPGAYAGLEAEERGQGWAIALNIRTMARINTPIIVTIIGEGCSGGALGMGVGDVVGMMEHAYYSVISPEACASILWKDAKKNTEAASILKLNAEDMLPLNIIDAIINEPLGGAHHDPQKAYMNMQQFILEQWQTLRHIPKDILLEQRYLKFRKMGQFTSHANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KA16</accession>
    <name>A0A0C1KA16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GS00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000104">
        <property type="protein sequence ID" value="KIC75977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75977">
        <property type="protein sequence ID" value="KIC75977"/>
        <property type="gene ID" value="DB41_GS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7293" checksum="64386B7AD4BBE626" modified="2015-04-01" version="1">MNISETLENLKVQLGEGIIKKNLFSWRSNRRGRQRKYKKGAYMLKAGRLRGLNRSYSHPLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBH4</accession>
    <name>A0A0C1KBH4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA_pol3_delta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FX00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384384.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000084.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76497">
        <property type="protein sequence ID" value="KIC76497"/>
        <property type="gene ID" value="DB41_FX00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.786"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="38"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="341" mass="38641" checksum="EBEF0526F955A768" modified="2015-04-01" version="1">MKYSHLKAFEKHLESAAPVHFAPVYTIICKDEFNRKIAYERLISHLLGEQISNPMALCIYSEEKVDINKVMAELHSLGSFVSKRVVVIHHAESLLKAATEKLLAYYENPNKNVYLVLTATSLNASTNFYKKSERVGIILEIAEEKPWEKEKSLKEWIDQTINHYGKQINPSASQALLKQMGTEQAIISQEIEKLVCYVGEKRQISLEDVDAVCIPVNTETIWQLGEALFRRDASTALRIAVALLQEGTPLLILLRQIRSQFQTDFQVCTILAQGGTGAEVSKQFGYMKGQILERHVQLARNYGMARFRRGMILIDEAETAAKNSSTDHSYLIERLIAKLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC26</accession>
    <name>A0A0C1KC26_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="9">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">murD</name>
        <name evidence="12" type="ORF">DB41_FD00110</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384083.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000066.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76652">
        <property type="protein sequence ID" value="KIC76652"/>
        <property type="gene ID" value="DB41_FD00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.652"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002148232" description="UDP-N-acetylmuramoylalanine--D-glutamate ligase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="113"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="115"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="446" mass="49219" checksum="A9CD16A5B236E9A6" modified="2015-04-01" version="1">MKLKKKRVLVIGLGLSGRAAASFLLKRQAYVWGVDDNLELLKNHQEIKDLITLGLVARHEAEKIEIQDFDFIVVSPGVPPSNPHYIQARQADIEIFGEVELAARFINQPLLAITGTNGKTTTTLLVAHVLNASGKAARALGNLGAPLTTELDALTVGAEEDILVAELSSFQLETLQSAVIDAGVVLNITPDHLDRYPDLQTYAATKLHLKDCLKPEGNLYVYEAVYNEYKKLLGDFKPLTYGYSSSCDFYLDPQLIYGEGQDPYPLPLAYQDVKNHDVENMLAAYALCKERGVNSEQFFNALSTFKKPAHRLEFVRSFKEIAYYDDSKGTNVDAVIRAVTSLKGEIILIAGGVDKGAAYTPWIKAFAGYVKYVFAIGQAAMKIKNDLSFSLPVEERSTLEAAIKDATALAKPGQVVLLSPGCSSFDMFRDYVHRGEEFKRIVNTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCR9</accession>
    <name>A0A0C1KCR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name evidence="3" type="ORF">DB41_EC00150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383737.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76867">
        <property type="protein sequence ID" value="KIC76867"/>
        <property type="gene ID" value="DB41_EC00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.443"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="125"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="320" mass="37639" checksum="9D42CB76BEF8D693" modified="2015-04-01" version="1">MSKPLPYLVLAYYHFPHLPDPQAEVTAHKQFFEGRDVTCRIYISENGINGQMSASREDGQAYMDWMHARPEFKDIHFKLHEYHEHAFPRCTVKYRKQLVAVDERIDLSKRGEHVSPQRWKEMLEKKDDHILIDVRNDYEWKVGHFEGAELPPCETFKDFKHYVEDLKEKIDPQKTPVMMYCTGGIRCELYSSILIKQGFDKVYQLEGGIINYGLQEGSDYWLGKLFVFDDRLTVPISDEETKTIATCHHCNQPCDTYLNCANMDCNDLFICCKECSKQYVGCCQEQCQQAERVRPFQEDKPHKPFRKKHKYINIASNTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDF9</accession>
    <name>A0A0C1KDF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DJ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000026">
        <property type="protein sequence ID" value="KIC77042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383454.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77042">
        <property type="protein sequence ID" value="KIC77042"/>
        <property type="gene ID" value="DB41_DJ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="14803" checksum="0642C2FAF84A9B56" modified="2015-04-01" version="1">MQKLMQERYIAEPENMSLNEKIQKLALKILFSPDSQEKLSAQQEWDQKGYQHIFRHLTTSPMDNNSPNTTWNQKANEIITSYKVRPVVIHEEEVKQMLGEHFKDLSSDVEANTSTLLQEVHACATSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDI1</accession>
    <name>A0A0C1KDI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DH00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77067">
        <property type="protein sequence ID" value="KIC77067"/>
        <property type="gene ID" value="DB41_DH00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="120" mass="14379" checksum="3CCD1FB8B3018AD6" modified="2015-04-01" version="1">MIRLVTYNVLFNLYDHNLDEENRWPNRLPRIVELIHEMRPDIINTQELYPTQVQEIVNLIGDDFSFFPGEKDEDGESYGIFYRTDRFELLSSQIDYLLSMVQLKDLKTDKIIHVFNTHMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDZ0</accession>
    <name>A0A0C1KDZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CT00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77192">
        <property type="protein sequence ID" value="KIC77192"/>
        <property type="gene ID" value="DB41_CT00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="8375" checksum="E8668FCE99DF8A84" modified="2015-04-01" version="1">MQILLIYSLKADIKECMYIRMKTSKKAKYPTLQVVEGVREGKKVKQRTIAHLGMIKSQQDLQRLKNLADKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE52</accession>
    <name>A0A0C1KE52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional NAD(P)H-hydrate repair enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide repair protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="16">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
                <ecNumber evidence="16">4.2.1.136</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">ADP-dependent NAD(P)HX dehydratase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NAD(P)H-hydrate epimerase</fullName>
                <ecNumber evidence="16">5.1.99.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="18" type="primary">nnr</name>
        <name evidence="14" type="synonym">nnrD</name>
        <name evidence="15" type="synonym">nnrE</name>
        <name evidence="18" type="ORF">DB41_CO00210</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15 16">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 14 16">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 14 16">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="15 16">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 16">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="16"/>
    <dbReference type="EC" id="5.1.99.6" evidence="16"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383116.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77252">
        <property type="protein sequence ID" value="KIC77252"/>
        <property type="gene ID" value="DB41_CO00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.55"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12 14 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 16" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 16" id="KW-0630">Potassium</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="17">
        <location>
            <begin position="9"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="126"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="406"/>
            <end position="410"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KIC77252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="497" mass="53476" checksum="EEE6C36B087643FA" modified="2015-04-01" version="1">MKVFTAQQMRNLEAQVYQDNASEEFFMEQAGASIAQMVEEYLNIHQLAKYIILLCAKGNNSGDAYVAGRYLLKKGYKVCALQAVSLEAGSPLCIKNYHRFKQAGGEAKDSSFSFPEEGVILDGFFGTGFKGSLQEPFASIVGRANTSKLPILAIDIPSGLNGDTGIAEGEVIQATQTLFLGAPKKGFFINDGWNYVGSLHPIDFGMPKEFIDQAPTGMIMLTKNIVQPLLPPIKRCWHKYERGYVTALAGSPHMPGAAILSARAALTAGAGIVRLIHPKEMEVALAAAPVELVRQSYCLQNLEAILEPINKASASYIGPGIGKTEETSYLLKYILKHIKKPCVLDADALTLLSESQVPLPKELVLTPHHGEMLKLLRIKQGPLASGKLLELAQSFTNDKNVTLVLKGAPTFILQPNLPIYVSPRGDAGMATAGSGDVLTGIIAALLAQGLPPPQAAILGAWLHAVAGEQAAKEKTSYCMTASDMIAYLPHAYKELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H1U5</accession>
    <name>A0A0C1H1U5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386799.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000215.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71659">
        <property type="protein sequence ID" value="KIC71659"/>
        <property type="gene ID" value="DB41_AS00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031869">
        <property type="entry name" value="YscO-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16789">
        <property type="entry name" value="YscO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="169" mass="20059" checksum="6CA9B1C17DE259A1" modified="2015-04-01" version="1">MNSIIYPLKQVLDIKRRRVEDAEKILKEKKELLTKEEEKLKNVEAVRDKLLAHQQDKLQQLRVESSHLTTSPKVQQMKIYLKVVAEKLQIEEKKVKDQKEQVKMAQKKVEEAKQELDRKRLEVDKLKTHQEDWTKERAKELEIIEAREQDELGSTMFLGRMQATKASKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3T4</accession>
    <name>A0A0C1H3T4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_Tnp_IS630 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KR00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72194">
        <property type="protein sequence ID" value="KIC72194"/>
        <property type="gene ID" value="DB41_KR00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002622">
        <property type="entry name" value="Transposase_14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01710">
        <property type="entry name" value="HTH_Tnp_IS630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_IS630" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="89" mass="10117" checksum="1337DDE4ABDFD0B9" modified="2015-04-01" version="1" fragment="single">MVYSHDLRKKALNYIKNGGSMATASEVFGVTVRTLTNWIKRKKQGDLAPKKRRPSPSKIDSEKLKLYIKQTSDAYLREIVEAFEVTISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3X8</accession>
    <name>A0A0C1H3X8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KQ00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72239">
        <property type="protein sequence ID" value="KIC72239"/>
        <property type="gene ID" value="DB41_KQ00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7863" checksum="AD1FA82F4A5A3BB1" modified="2015-04-01" version="1">MLSKSFKDTENFPAYQEPLTFKVFCQSRGKVFSSSLHSSIFKLYGYGSISSIFLYVLRFSLYDALKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H4P3</accession>
    <name>A0A0C1H4P3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-antigen export system ATP-binding protein RfbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rfbB</name>
        <name evidence="6" type="ORF">DB41_KK00200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244058.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72494">
        <property type="protein sequence ID" value="KIC72494"/>
        <property type="gene ID" value="DB41_KK00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="49"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="272" mass="30447" checksum="C228E48671187F32" modified="2015-04-01" version="1">MGSLNIVEVKNVSKKYTIFHDQPPLGQTTLVETLAMHGRRFWKRMGGHIRRAAAAAEEKQTEEFWALKDISLAIEEGDRFGIIGRNGAGKSTLLKLLSRIIMPSDGEIFLRGKISSLLEVGTGFHPELTGRENVFLNGAILGMSKREIARKFDEIVEFAEIEKFLDTPVKRYSSGMYTRLGFSIAAYLDPQVLVLDEVLAVGDAPFQAKCIKKMRELALSGRTIIFVSHNTHSLLEICNKGIYLENGRQIEVGSIEKCIKAYEQKIQENLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H657</accession>
    <name>A0A0C1H657_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JY00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000181">
        <property type="protein sequence ID" value="KIC72954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386254.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000181.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72954">
        <property type="protein sequence ID" value="KIC72954"/>
        <property type="gene ID" value="DB41_JY00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="60" mass="6740" checksum="B0BD4A81537B4A4C" modified="2015-04-01" version="1">MIATQKHSTSSRRKAEQKPSTSSYRLQGIVDCSLLNKLADTPGDKDTNSFDLLFQFLYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6B9</accession>
    <name>A0A0C1H6B9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JV00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386243.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000178.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73019">
        <property type="protein sequence ID" value="KIC73019"/>
        <property type="gene ID" value="DB41_JV00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1834"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="69" mass="7773" checksum="A4D36AA3FE44FD94" modified="2015-04-01" version="1">MKVLFILIIRIYQWTISPLLGSTCRFTPSCSNYALQAIEKHGVCRGTGLAIKRICRCNPRHLGGRDEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H701</accession>
    <name>A0A0C1H701_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JM00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386172.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73259">
        <property type="protein sequence ID" value="KIC73259"/>
        <property type="gene ID" value="DB41_JM00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="135" mass="14781" checksum="FE027FBB17B460D6" modified="2015-04-01" version="1">MNAGEESKDPSQESIREVETEHPKKGEKKIHGLIDFAKTNTKDSIAYIIMILGIILLFFEQFSGGMLIGIISGLYYSVEIQDLFSHFNEFIDEQGIVRGIVLGVVAIALFISAPGIFVGALLAVIIKYLFSPSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H852</accession>
    <name>A0A0C1H852_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_JG00040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000163">
        <property type="protein sequence ID" value="KIC73564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386124.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000163.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73564">
        <property type="protein sequence ID" value="KIC73564"/>
        <property type="gene ID" value="DB41_JG00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="40"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="293"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC73564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="385" mass="42349" checksum="22E27E2ECA0FB8B7" modified="2015-04-01" version="1">MLVVAFKMLIGDKAKFLGLIFGIFLSSFLICQQSAIFLGLVERSYRLITDIPTPEIWVMDPGTEHIDKIREMSDSQIDKVRSVPGILWAAPLSMTYLPLKLSNGLFHEAQVVAIDQNSLLGAPQHMVKGVVESLRHEGGIILDQHAVQKALVTDGADGKPSYLKLGDTLEVADQYVVVVGIAQLTLGFYPQPIMYMAYQQYKNLTPFKNRHLGFILARVQPGENVEKVVQHIKDQTGLSAFTREGFKWRSIWYFLGTGVLINFGTTVLSGFLLGIAIVGIMFYMLTIDSLPFFAMLRALGATPLTIAQMIYFQALVAGIIGFGLGLGAATLAGQMIILSQGTIAFLFPPLILLLAAFTIVSINLLAARICIRRVLKEDPKIVMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9W5</accession>
    <name>A0A0C1H9W5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AU00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000217">
        <property type="protein sequence ID" value="KIC71628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386865.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000217.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71628">
        <property type="protein sequence ID" value="KIC71628"/>
        <property type="gene ID" value="DB41_AU00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="296" mass="33900" checksum="519C7B4E9D6C5B08" modified="2015-04-01" version="1">MISNIFDNYLSKVDKFTQKSFNQLIENNFSKNLNYIIAVVEDAKNQVSLYDGCTFAKIQLELGAEAKYNPETAEKMAKIYYYCVNQYCGTNQTQLYYPNYVGRQEDLKEIACKAYIFASDSSLNPSKRAEYQFDLGHCFYQGKGTEQNFAQAFNCYQKAGLEGNYPPALFMVGHCLERGEGVPKDEETALQWYLKAASYLDDVDILRHVAQKFEEKGQIEIAHLLYQKAAQNHDSVAIDYLIKFYEQKGEEQYQEAINKWKSQLAKVVQQLNPDSLLKKSYSLPSISYSGEGTIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA59</accession>
    <name>A0A0C1HA59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4116 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IR00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74234">
        <property type="protein sequence ID" value="KIC74234"/>
        <property type="gene ID" value="DB41_IR00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="27"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="84" mass="9855" checksum="B8904286578E2628" modified="2015-04-01" version="1">MRLSSKTVRRFIMLLAQHYRIIGKSFLALFKKKGLALQYASEELRNHEEIVLAAVQQDSRALRYASHKLQKDLKPMVRQEQTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAD0</accession>
    <name>A0A0C1HAD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_11</name>
        <name evidence="3" type="ORF">DB41_AJ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000208">
        <property type="protein sequence ID" value="KIC71788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244106.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000208.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71788">
        <property type="protein sequence ID" value="KIC71788"/>
        <property type="gene ID" value="DB41_AJ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2168"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="446" mass="50387" checksum="C81742359C4EE49B" modified="2015-04-01" version="1">MHPISSTSIESLPNELLLPILEACVVPSLFSVCKRWHHLLASEVMPPLYKQIGKVHVPQGDVNEQALIVDRIYKLEEKLSEAAKVNAIFRQIFTLAKSLSTLEFKVQIEEKRDLTLANYSSYLVNINRLLLWKKLPGGEEYLSREEIKHLPLEKKGELLREWMEENCKSIMALDLPKAGLTYLPPEIGQLSQLKRLDLKENQLTSLPVEIGQLSQLQGVNLNQNQLASLPAEIGQLSQLQYLFLNQNQLTSLPVEIGQLSRLKKLYLSENQLTALPAEIGQLSKLRWLQLNQNLLTSLPAETGQLSQLQTLDLKENQLTALPAEMRQLSQLEELNLNQNQLSSLPAQIGQLTQLLQLYLNQNQLASLPAQIGQLYRLKRLDLSQNQLTALPTEIGQLSQLAWLSLNQNQLTSLPIEIGQLSDLQTLELAGNPLKDIAEKIRQLFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HAJ4</accession>
    <name>A0A0C1HAJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative metal transport system membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_IP00040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243997.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74404">
        <property type="protein sequence ID" value="KIC74404"/>
        <property type="gene ID" value="DB41_IP00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1635"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="36844" checksum="038CD97D98F31A64" modified="2015-04-01" version="1">MNSINSTYFNPYTNQNFFGFFLQLFVRLYSFIVGKISLSEMVSDEIQMVVLIGVAISAALVGTFLVLRKMTMLANSLSHTILLGIVITFVLTQNSLLENEAYYSPIDIKIMLLASLAVGLLTALLTDCLTKIARLQEDASMGIVFTSLFALGIVLVTLLTRNAHVGIEVVMGNVDALQKEDCKFVWVIVFLNVLSIILFIKEFKITTFDPYLSKALGISTVFFNYLLMVQVAATTMGAFRAVGVLIVLAFITGPVLTARLITHNLKMLLFLAAALGSLASVIGVALARHILTVYHIPLSTSGLVVCTITTLFGFTLIVKTIQVKRLKSRDLVLPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBE7</accession>
    <name>A0A0C1HBE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IF00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74754">
        <property type="protein sequence ID" value="KIC74754"/>
        <property type="gene ID" value="DB41_IF00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4427" checksum="552B69E47334C4BC" modified="2015-04-01" version="1">MNSSNSFQSDRQMLKVAEKSGISCLSRKLELINQCPRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC62</accession>
    <name>A0A0C1HC62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aliphatic sulfonates import ATP-binding protein SsuB</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssuB</name>
        <name evidence="5" type="ORF">DB41_HY00150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385551.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74989">
        <property type="protein sequence ID" value="KIC74989"/>
        <property type="gene ID" value="DB41_HY00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="243" mass="27438" checksum="8F62F3AB12C7E108" modified="2015-04-01" version="1">MPAFLLKIQNLSFSFGEKKILKNLSLDISPNEVISLVGWSGSGKTTLFKLLAGILPLETGVISVVTGQPAESIAFMAQEDLLLPWRTILENLLLPTELGKKPSSSLSLQQKALSLLSEMGLKESANLYPEQLSGGMRQRASLARALLQQRPLLLLDEPFNKLDVVLREQVYELLRKIKEKLNCTILMNTHDFRDAIYLADRILLLHDGSIHKIWKIENKLRRDPLHYATLSEEIRQALFNLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCH6</accession>
    <name>A0A0C1HCH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72483">
        <property type="protein sequence ID" value="KIC72483"/>
        <property type="gene ID" value="DB41_KK00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5125" checksum="1727D98C97129005" modified="2015-04-01" version="1">MPESFEGLTDTQWRILQPLLPQSSSKNLKGKPHNPWRKICDSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE94</accession>
    <name>A0A0C1HE94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein UmuC</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">umuC</name>
        <name evidence="5" type="ORF">DB41_HG00040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75749">
        <property type="protein sequence ID" value="KIC75749"/>
        <property type="gene ID" value="DB41_HG00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1172"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025188">
        <property type="entry name" value="DUF4113"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13438">
        <property type="entry name" value="DUF4113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="SSF100879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0741">SOS mutagenesis</keyword>
    <keyword evidence="3" id="KW-0742">SOS response</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="4">
        <location>
            <begin position="24"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="440" mass="50447" checksum="E4ED5C64B1A1E491" modified="2015-04-01" version="1">MLPLIFKYGGLLLMSFTGRSEFMYALVDCNNFYVSCERVFNPRLIGKPVVVLSSNDGCIIARSKEAKFLGILMGAPAFEYRDLFRKYDVKVLSSNYTLYGDMSHRVMRTLQQFSPEIDIYSIDEAFLKVDTVDKEAYCREIQRIILQHTGIPTSIGLAPTMTLAKIANDMAKRYSACHNVFSMEAFEVREKVLCQLSIDEIWGIGKKISSYLHRQNIHTASEFKNSEDLWIKKNLSVTGLRIAWELRGVSCLSLKEAPASKKSITCSRSFSKAVSDLNELLEAISTYASTAAEKLRKQQSRVSFIDVFLMTNKHHHSPYYYNNMQITLPQPSDYTPKIITYAKEGVRHLFREGFLYKKTGLTLGGLVSKGDYQLDLFEENHFSNKKEQTLINLIDQLNHQYGRRVIKMAAEGIKQPWKARQENCSPRYTTCWQDILTIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEF6</accession>
    <name>A0A0C1HEF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HD00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000114">
        <property type="protein sequence ID" value="KIC75819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75819">
        <property type="protein sequence ID" value="KIC75819"/>
        <property type="gene ID" value="DB41_HD00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="38" mass="4332" checksum="D01A69D3B7652B38" modified="2015-04-01" version="1">MKSDTEYEVILVDATETPVERPKKSKNAIIQGKRKNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEL1</accession>
    <name>A0A0C1HEL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative type III secretion chaperone SycE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75879">
        <property type="protein sequence ID" value="KIC75879"/>
        <property type="gene ID" value="DB41_GZ00430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010261">
        <property type="entry name" value="Tir_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05932">
        <property type="entry name" value="CesT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="162" mass="18402" checksum="BBF78885619D30E0" modified="2015-04-01" version="1">MNEVLMPSHNLESLLKDLGEKIELSHLEPTGNNNITLLLKGNNEVVLQKHNSQPYLIISFEILELPIGRFRENIFREALKFNHLNKAHEGIFAFSKKTQMFFLFDMLPFDEISGEQVNAIMQNLSEKVTLWKEALNRGEIPTIGFSSLTSPEGAGSFFGIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGB5</accession>
    <name>A0A0C1HGB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ABC transporter, permease protein</fullName>
            <ecNumber evidence="2">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GG00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76409">
        <property type="protein sequence ID" value="KIC76409"/>
        <property type="gene ID" value="DB41_GG00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="428" mass="48276" checksum="E8F2AFC0BDE560F8" modified="2015-04-01" version="1" fragment="single">MFELSVACKYLRPRWRQLSVSIISLISILVIALVVWLIVVFFSVTSGLEKRWIEKLIALTAPVRLTPTEAYYNSYYYQIDSISENSNYTLKTIGEKWRADQSDPYDPQLDIEVPSNWPKPDREEDGSLKDPVKKAFFIIKNLPYSPSIKARDYEVCASNLRLRMLRKTPETNPTLTQAFLSQATYLGSLDNENLAILKATLPISDADINNLLYTLSIASENVQEDHPASADSVNQQLLRERLKTFFKYTEVNWLKTPPAGWALPTVLQKNASLPKQLPGGFQMSALPILESLDKILYLQKILFDVNFEVEGQQVSGRIPMGNLLIAHPKIKTHFNNSPPLSPFWFYKAGNSQEDLKVFLPKDAALGEGILLPKPFREAGVLLGDRGYISFQTPTVSALQEQRIQVFVAGFYDQGLIPVGGKFILVNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGR6</accession>
    <name>A0A0C1HGR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HicA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FU00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000081">
        <property type="protein sequence ID" value="KIC76529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384348.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000081.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76529">
        <property type="protein sequence ID" value="KIC76529"/>
        <property type="gene ID" value="DB41_FU00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="84" mass="9598" checksum="DCEAA40687BF1BF4" modified="2015-04-01" version="1">MSKKHQRTLEAIFKQPVQSNVVWKDIEALLRHVEAEITEGEGSRIRIALNGIRATFHRPHPKKETDKGALVSMRRFLENAGVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGT2</accession>
    <name>A0A0C1HGT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase, IS5 family, OrfB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FR00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000079">
        <property type="protein sequence ID" value="KIC76539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76539">
        <property type="protein sequence ID" value="KIC76539"/>
        <property type="gene ID" value="DB41_FR00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.754"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="47"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="104" mass="12897" checksum="434F56168D399E6B" modified="2015-04-01" version="1">MGYQGTVLKQTCQDQYNIDFEIVKRPPRRFWVHEDKIEEFLKTIDLSFKVLPKRWIVERTFAWIGRNRRTSKDYEYLTTTSENWIYLSMIRLMLKRIDKLKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGX1</accession>
    <name>A0A0C1HGX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76564">
        <property type="protein sequence ID" value="KIC76564"/>
        <property type="gene ID" value="DB41_FN00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="81" mass="9570" checksum="638ECE88601A357C" modified="2015-04-01" version="1">MVAQICLNDQVIPWFKKQDVRALRILTDHGTEYCGARENHEYELYLAIENISHSRTNARHPLNQWNLRKILSGHPKKNFMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHG5</accession>
    <name>A0A0C1HHG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor P</fullName>
            <shortName evidence="8">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">efp1</name>
        <name evidence="8" type="synonym">efp</name>
        <name evidence="11" type="ORF">DB41_EO00120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383902.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76759">
        <property type="protein sequence ID" value="KIC76759"/>
        <property type="gene ID" value="DB41_EO00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.544"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="10">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="9">
        <location>
            <begin position="129"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC76759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="185" mass="20940" checksum="D85111758367CC04" modified="2015-04-01" version="1">MVMSNQLTPGMTISINNKLYRVETTVKVMVPKGTPFIKTKLRDLTSNELIEKNFKLNQSIKDVNLAERRLEFLYLEGKDYLFLDIENLNQILIPQHIIGNSINYLKEGVEVKASFFGETIFAVELPQFLELMVAKVEGGENKSILANASKAALLETGAKIEVPPFIEAGDIIKIDTRSYEYIQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHK1</accession>
    <name>A0A0C1HHK1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rpsQ</name>
        <name evidence="4" type="ORF">DB41_EI00040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383809.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76789">
        <property type="protein sequence ID" value="KIC76789"/>
        <property type="gene ID" value="DB41_EI00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.487"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="79" mass="9304" checksum="BE25CD05574C5E54" modified="2015-04-01" version="1">MEERGNRKEKKGIVVSNKMTKTLVVKIERRLRDPVYGKVTKRNKKVFAHNEGRPYEIGEQVTIVETRPLSKLKRWRVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHR3</accession>
    <name>A0A0C1HHR3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dnaE</name>
        <name evidence="10" type="ORF">DB41_EE00020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000044">
        <property type="protein sequence ID" value="KIC76849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76849">
        <property type="protein sequence ID" value="KIC76849"/>
        <property type="gene ID" value="DB41_EE00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.454"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041931">
        <property type="entry name" value="DNA_pol3_alpha_thumb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_alpha" evidence="7">
        <location>
            <begin position="223"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_finger" evidence="9">
        <location>
            <begin position="497"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="HHH_6" evidence="8">
        <location>
            <begin position="733"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1127" mass="128843" checksum="C57F19951BDEC1BA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHS4</accession>
    <name>A0A0C1HHS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tyrosine-specific transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tyrP_2</name>
        <name evidence="9" type="ORF">DB41_IT00060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386061.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000151.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74143">
        <property type="protein sequence ID" value="KIC74143"/>
        <property type="gene ID" value="DB41_IT00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="396" mass="43342" checksum="645FF45E6A49F884" modified="2015-04-01" version="1">MNNTASLLKGALLVAGTSIGGGMLALPVATSLGGFVPSLLTYFFCWVFMASTGLLFLEVSTWMKGEANIVTMAYTTLGSLGKWAAWIIYLFLFYCLNLAYIVGCGNLVSQFLVNIVPAHYGSLLFVLLFGPFVYAGAQVISHLNIMLMGGLAVFYAAFVILGAPHVNSQHLLYQNWSLAMVGLPIAFTAFAYQGIIPTLVHYMHSDIRLTRLAILIGSFIPLVTYMIWQWLIQGIVPTFGAGGLIETLQKGENAVVPLKHFLGTPVIYIIGQFFAFFALVTSFFGVTLGLLDFLADGLQLKKSSANKFFICLAIFVPPLLISYSHPHIFLEALDYAGGYGCALLLGLLPVLMVWTGRYVHGFKGEYTFPGGRISLIFLSLFVIFELACESYIKFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HII5</accession>
    <name>A0A0C1HII5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DF00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000022">
        <property type="protein sequence ID" value="KIC77074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383396.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77074">
        <property type="protein sequence ID" value="KIC77074"/>
        <property type="gene ID" value="DB41_DF00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.227"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="340" mass="39927" checksum="858952AF7EB38D67" modified="2015-04-01" version="1">MNEIHLLSKDERELFFRAATDIKNMPFEIIEKDYWVVWVLERLFSLEKMRPHLTFKGGTSLSKVYGLIDRFSEDIDLSIEREFFGFGAPHDPENAPSKKKQNAIIDNLSKACSNYVQTQMLAELKDAFAAKLGTIDGWQVFPDQEDPDAQTLLFEYPSETSKAGYIRPLVKIEIGARSEHWPVSEHRIKSYAKEALKEKIHESEIWIRVLNAERTFWEKATILHQYAHLPEDKKLPPRISRHYYDFFRLLNSEIKEKALIEIALLERVAIHKSIYFASSWANYGTARKGTLKLFPPPRILKELEKDYVLMKSMFFREIPEWELILKTIDTFEKEFNYVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIM8</accession>
    <name>A0A0C1HIM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">recJ</name>
        <name evidence="9" type="ORF">DB41_IP00130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386029.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74413">
        <property type="protein sequence ID" value="KIC74413"/>
        <property type="gene ID" value="DB41_IP00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1643"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="87"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="337"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="471"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="585" mass="66160" checksum="123E32345A83D0A6" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIY9</accession>
    <name>A0A0C1HIY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Segregation and condensation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">scpA</name>
        <name evidence="2" type="ORF">DB41_IM00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000144">
        <property type="protein sequence ID" value="KIC74503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385993.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000144.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74503">
        <property type="protein sequence ID" value="KIC74503"/>
        <property type="gene ID" value="DB41_IM00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="242" mass="27930" checksum="127265DB755DCADB" modified="2015-04-01" version="1">MKNLYSEDVFALDNFEGSLDFLLHLVQKHEIDPVEISLKKITEQYIQKLKEWQSSSVDSGAEFIASASFLLWLKSRMLLPTHEQPLSLGEEEHDPRFDIIHQLLDYCRFKEAAKNLTQLEMSQSAHYLREPEPLGENNKPLGIEHLTLEDLADLFKQALAKAPIKTAKFIQEEEWKVADKIKAIRQYLKVNHQLEIEQLFLNATSKLEIIVIFLAVLELMKIGESYLIKDVASQKILLCVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKL0</accession>
    <name>A0A0C1HKL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative thiamine biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">DB41_HY00240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74998">
        <property type="protein sequence ID" value="KIC74998"/>
        <property type="gene ID" value="DB41_HY00240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1418"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="54"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="546" mass="61991" checksum="FDB74A45D7D7C743" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLL9</accession>
    <name>A0A0C1HLL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HS00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000129">
        <property type="protein sequence ID" value="KIC75303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75303">
        <property type="protein sequence ID" value="KIC75303"/>
        <property type="gene ID" value="DB41_HS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="6933" checksum="6B16369CCD604BBA" modified="2015-04-01" version="1">MQKPMHAVILKNREIFPQASAKFLANDKESTAYIHSVISTNFSLGTFNKDKTYNFSMSVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HMU0</accession>
    <name>A0A0C1HMU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HI00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75648">
        <property type="protein sequence ID" value="KIC75648"/>
        <property type="gene ID" value="DB41_HI00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1236"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="678" mass="75882" checksum="B274162D2F053196" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNT2</accession>
    <name>A0A0C1HNT2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperonin GroEL</fullName>
            <ecNumber evidence="3">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-60</fullName>
            <shortName evidence="3">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groL2</name>
        <name evidence="3" type="synonym">groEL</name>
        <name evidence="3" type="synonym">groL</name>
        <name evidence="6" type="ORF">DB41_GU00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384871.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75953">
        <property type="protein sequence ID" value="KIC75953"/>
        <property type="gene ID" value="DB41_GU00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1019"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="87"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="480"/>
            <end position="482"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="541" mass="58148" checksum="C6CC97EF760268DB" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNV7</accession>
    <name>A0A0C1HNV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GT00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000105">
        <property type="protein sequence ID" value="KIC75973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75973">
        <property type="protein sequence ID" value="KIC75973"/>
        <property type="gene ID" value="DB41_GT00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="3937" checksum="4E45A6A99E26B115" modified="2015-04-01" version="1">MEEGANCARAGGQLLVSPARGGGKNSCRPGGQFIMSLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR87</accession>
    <name>A0A0C1HR87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FH00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76633">
        <property type="protein sequence ID" value="KIC76633"/>
        <property type="gene ID" value="DB41_FH00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6455" checksum="5D63BA078ED79728" modified="2015-04-01" version="1">MSDLESKNQNIQETTPHQDEKFLSSVNPEGEELCLPIPSLEEAEQEISEEPVVEKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRB8</accession>
    <name>A0A0C1HRB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein YqfF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yqfF</name>
        <name evidence="3" type="ORF">DB41_FB00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042243397.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76668">
        <property type="protein sequence ID" value="KIC76668"/>
        <property type="gene ID" value="DB41_FB00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.622"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011624">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_extra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011621">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_intra"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07698">
        <property type="entry name" value="7TM-7TMR_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07697">
        <property type="entry name" value="7TMR-HDED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="HDc" evidence="2">
        <location>
            <begin position="496"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="726" mass="82579" checksum="703A0F5389E48696" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRD6</accession>
    <name>A0A0C1HRD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FA00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000063">
        <property type="protein sequence ID" value="KIC76688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384023.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000063.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76688">
        <property type="protein sequence ID" value="KIC76688"/>
        <property type="gene ID" value="DB41_FA00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="23140" checksum="EF8971B268E799F5" modified="2015-04-01" version="1">MEVNRVRLERLNVEFKDLQSGDMSQHTFAELILIEHIPGGAAPLCYILKNDKIFSEALPENFQYLLSTLDRTAFYPIGEVLAINKLHKYVLLKDNNSISYNYLIITFSNHYALINYAFLAGIHTLMDALRVRKKIPAAFPDPIKASQPKERTKLKGTKTLSKNLSFLQSLQSLQSRKINKLKDRGLTCSLNNPNKRLYEVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRK7</accession>
    <name>A0A0C1HRK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EO00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76763">
        <property type="protein sequence ID" value="KIC76763"/>
        <property type="gene ID" value="DB41_EO00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.547"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13586">
        <property type="entry name" value="DDE_Tnp_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="40"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="17629" checksum="A1BC16AE8E09F4F0" modified="2015-04-01" version="1">MDTQGFLLTCYVGAADENDQTALIKLLDKCKNLFSTITKVWADMGYQGTALKKTCKDQYNIDFEIVKRPPRRFWVQEDKIEEFLKTIDLSFKFLPKRWIVERTFAWIGRNRRTSKEYEYLTTTSENWIYLSMIRLMLRRIDKLKEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSU1</accession>
    <name>A0A0C1HSU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DB00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243759.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77098">
        <property type="protein sequence ID" value="KIC77098"/>
        <property type="gene ID" value="DB41_DB00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="425"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="641" mass="68333" checksum="BCB11FA7DA99F971" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSV7</accession>
    <name>A0A0C1HSV7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">argS</name>
        <name evidence="13" type="ORF">DB41_CZ00040</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77123">
        <property type="protein sequence ID" value="KIC77123"/>
        <property type="gene ID" value="DB41_CZ00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.178"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="8"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="473"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="588" mass="66733" checksum="B67D3CE9C90B2DCC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT78</accession>
    <name>A0A0C1HT78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CK00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000002">
        <property type="protein sequence ID" value="KIC77278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77278">
        <property type="protein sequence ID" value="KIC77278"/>
        <property type="gene ID" value="DB41_CK00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.20"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="126"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="151"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="201"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="226"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="251"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="276"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="326"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="388" mass="43970" checksum="AE1DBFB259BDDF69" modified="2015-04-01" version="1">MTLKLNLFLSLNKLLRRYRMGISNLSQACRRIDDIADYIPVISTVTNLVDLFQKCIISTFISKESLVKNHYYKHLSDKSFRRCITLLIPVLGNLTIAILDFLHQKKDNEKQQDKNVSSKPTTLQKDKEALVAIVKKEGLALKGARLELQKDKDIVLTAVKQNGEALQYASRELRDNKNIVLAAVEQNGWALEFASPRLQNDRDVVLTALRQNGWALRYASPRLKDDPKIVLAAIQENGWALAEASERLRKNKKMIIAAIQNEGWALEEASEELRNDKDIVLAAVKKRPSRLRYASEKLKNDKDVVLAAVKQDGYALEFASPQLQNDKDVVLAAIQQNGWALQYVSSALKDNLDIVQAAVQQNGWALQYASRELQKNEELIKLARLTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKI8</accession>
    <name>A0A0C1JKI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_10</name>
        <name evidence="3" type="ORF">DB41_AI00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244105.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71805">
        <property type="protein sequence ID" value="KIC71805"/>
        <property type="gene ID" value="DB41_AI00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2167"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="48494" checksum="23ADD4C8AAF87F1E" modified="2015-04-01" version="1">MHPISSTSIESLPNELLLPILEACAVPSLFSVCKRWHHLLSSEAMPSLYKKIAQLHFPKKNATTQRTLLLAKIYQLNPGLTSTEKVYQVFKQVFTLAKSISPLEFKWKTEEKRGLTLANYSSYLVNINRLLLWKKLPGREEYLNREEIKHLSLEKKGELLRDWIEENCKNITTLDLSRLSLTYLPPEIGQLSQLQTLDLRENQLTALPTEIGQLSKLQRLELNQNQLTALPTEISQLSQLQYLYLNQNQLTSLPAEIGQLSQLRWLDSSQNQLTSFPVEIGQLSQLRVLKLDQNQLTALPAEIGQLSKLQWLQLNQNQLTSLPEEIGQLSQLIRLYLSQNQLAALPAEIGQLSKLRYLYLNQNQLTALPAEIGQLSQLQTLDLRENQLTALPAEIGRLSQLTELELAENPLKDIAEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLW9</accession>
    <name>A0A0C1JLW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative thiol-disulfide interchange protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dsbD</name>
        <name evidence="9" type="ORF">DB41_KP00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72270">
        <property type="protein sequence ID" value="KIC72270"/>
        <property type="gene ID" value="DB41_KP00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1995"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02953">
        <property type="entry name" value="DsbDgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035671">
        <property type="entry name" value="DsbD_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="545"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="620"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC72270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="751" mass="83293" checksum="3D5CD6992DB20442" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM06</accession>
    <name>A0A0C1JM06_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">clpP2</name>
        <name evidence="5" type="synonym">clpP</name>
        <name evidence="11" type="ORF">DB41_AV00160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71576">
        <property type="protein sequence ID" value="KIC71576"/>
        <property type="gene ID" value="DB41_AV00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2252"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KIC71576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="221" mass="24697" checksum="E67214CA9321F3DE" modified="2015-04-01" version="1">MTCGIFHLISLKKLQEIRIVMNEERSKNSLTPYVIEDTGRGERSMDIFSRLLKDRIVFIGTDITDHVANVVVAQLLFLRMEDPKKDVNLYINSMGGYITAGLAIYDVLQWMGCRINTYCIGQASSMGALLLAAGTKGHRYALPNSRIMIHQPIGGVGGSSADIALQAKEILYLKKRIHEIMAEATGQNVERIAQDSERDFYMSPLEAKEYGLIDEVVTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMD1</accession>
    <name>A0A0C1JMD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATP-dependent helicase YwqA</fullName>
            <ecNumber evidence="3">3.6.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ywqA_2</name>
        <name evidence="3" type="ORF">DB41_AQ00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244115.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000213.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71711">
        <property type="protein sequence ID" value="KIC71711"/>
        <property type="gene ID" value="DB41_AQ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2188"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="279"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="452" mass="52437" checksum="D74DA48B127B463C" modified="2015-04-01" version="1">MGLGKTHQAMALIAAIINHGEKQKQKGNSYFLIICPTSVIYHWQDKLAQYLPNLRVSTFYGTHRSLDEFQEHYDILLTSYGVWRIEHQLLSKISFELAIFDEIQIAKNYRSRLYATLAHVNAHMRLGLTGTPIENHLRELKSLFDLVLPTYMPGEKDYREYFVKPIDKKQDLKRKALLSRLINPFVLRRKKENVLNDLPEKTEEISHCGLTESQAILYNNVVEQSRQVVLDKLTHGSQPIPYLHIFAILSYLKQICDHPACYLKTPSEYKLYQAGKWDLFIELLKEARESHQKVVVFSQYLNMLDIIQKYLEERHIGFAAIRGSTINRGEQLKRFNEDPQCEVFLGSLQAAGLGVELTAASVVIHYDRWWNAARENQATDRVHRSGQTRGVQVFKLVTKGTFEEKIDKMITRKGKLMEDIVGVDDHRLLKQFNRDEIIELLQNVNPTSLQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMS4</accession>
    <name>A0A0C1JMS4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groS_2</name>
        <name evidence="3" type="synonym">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="6" type="ORF">DB41_KI00040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386337.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72560">
        <property type="protein sequence ID" value="KIC72560"/>
        <property type="gene ID" value="DB41_KI00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1896"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="97" mass="10510" checksum="C0B558BFA7C251CF" modified="2015-04-01" version="1">MTKIKPLGNRVLIKRSKPQPTKGGILLPDSAQEKPKEGVIVAVGPGKLNDEGQREPLNVQVGDRILFSSYAGTEIKNSDEEDELLIMSEDDILGVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNB1</accession>
    <name>A0A0C1JNB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KD00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72725">
        <property type="protein sequence ID" value="KIC72725"/>
        <property type="gene ID" value="DB41_KD00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5572" checksum="153D401857869A70" modified="2015-04-01" version="1">MQKKFKYIQMIELQIIATQKHATFGGPKAEQKPSISSYRLQGTVACALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNS0</accession>
    <name>A0A0C1JNS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KR00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72186">
        <property type="protein sequence ID" value="KIC72186"/>
        <property type="gene ID" value="DB41_KR00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="40" mass="4600" checksum="5A8B38774DA1154C" modified="2015-04-01" version="1">MLKKIGNFMKILFKLKDIQPTERGGVVSSVLYGKLLNYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPX0</accession>
    <name>A0A0C1JPX0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JM00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73255">
        <property type="protein sequence ID" value="KIC73255"/>
        <property type="gene ID" value="DB41_JM00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="6229" checksum="B23F52248D929E17" modified="2015-04-01" version="1">MANADNHKNGTAISPNDSTVTSIKQLPDELLLHIFSFMQAFCLLELELTCHQWKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPY5</accession>
    <name>A0A0C1JPY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromosome partition protein Smc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">smc</name>
        <name evidence="4" type="ORF">DB41_KI00150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72571">
        <property type="protein sequence ID" value="KIC72571"/>
        <property type="gene ID" value="DB41_KI00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1909"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="3">
        <location>
            <begin position="248"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="52"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="395"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="591"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="711"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="905" mass="105200" checksum="5C6785F19676DCA0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQC1</accession>
    <name>A0A0C1JQC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">DB41_KD00160</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72716">
        <property type="protein sequence ID" value="KIC72716"/>
        <property type="gene ID" value="DB41_KD00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1874"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="56"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC72716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="518" mass="59137" checksum="4EE5E190E3055C3B" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQI3</accession>
    <name>A0A0C1JQI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JJ00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000166">
        <property type="protein sequence ID" value="KIC73475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73475">
        <property type="protein sequence ID" value="KIC73475"/>
        <property type="gene ID" value="DB41_JJ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="91" mass="10566" checksum="44EAD1AFBBB1E88E" modified="2015-04-01" version="1" fragment="single">MFSQPLPFIKEYLNQLEVALKQENPHNNLSKIQWCWLAFCLMGILVTNSICWAKFERAGLKSYKKMALSAMFRRAKIAWNSLLICSVRAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQS6</accession>
    <name>A0A0C1JQS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JH00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386144.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73550">
        <property type="protein sequence ID" value="KIC73550"/>
        <property type="gene ID" value="DB41_JH00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="90" mass="10105" checksum="E0F56314B1310DCB" modified="2015-04-01" version="1">MGTNSPIPHDKVKMTIECTPDERAYIKILAAKAHLNLSELVLSYLRKDFPCTPNKETLAAMKELDEGGGMIYKSMDDFWENMGVKPTARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JR67</accession>
    <name>A0A0C1JR67_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor P</fullName>
            <shortName evidence="8">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">efp2</name>
        <name evidence="8" type="synonym">efp</name>
        <name evidence="12" type="ORF">DB41_JC00040</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000160">
        <property type="protein sequence ID" value="KIC73665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386112.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000160.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73665">
        <property type="protein sequence ID" value="KIC73665"/>
        <property type="gene ID" value="DB41_JC00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1720"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="11">
        <location>
            <begin position="69"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="10">
        <location>
            <begin position="131"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC73665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="20955" checksum="F31B93EE9FA54AF1" modified="2015-04-01" version="1">MAQISTNEFKAGIKVEVDGQPYTIVSNEFVKPGKGQAFNRVKLKHLTTGRTIEQTFKSGDKADVADVVEAEMRMLYKEADGVVFMDDKTFDQVKIPFVSIGDNAQWLMEDHLYFIVFYKGQPVTLEPPTFIDMIVTETSPGARGNTASGRVLKPAVVESGAKIQVPIFVEQGEKVKVDTRTGEYVSRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JS05</accession>
    <name>A0A0C1JS05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JM00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73256">
        <property type="protein sequence ID" value="KIC73256"/>
        <property type="gene ID" value="DB41_JM00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="81" mass="9946" checksum="9C23FBC6B6F2F793" modified="2015-04-01" version="1">MLQNMEKVKWKMKYKLFCVFFKNFYHRMLSLNYSRYGDLIGRLQNSFFLKVPYRVNIFQNVFNIGFALRPCLWLNFPLMAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSG6</accession>
    <name>A0A0C1JSG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IU00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000152">
        <property type="protein sequence ID" value="KIC74070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74070">
        <property type="protein sequence ID" value="KIC74070"/>
        <property type="gene ID" value="DB41_IU00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="94" mass="10899" checksum="D7AF00584CE0D0DE" modified="2015-04-01" version="1" fragment="single">PVRFLALEDNHYIASTFHPDFKIFKLYQHTPAIKGCGIILPFLPDTYPWVNSYHIHASYDGRKLVFCDEHGWLHLWDFAHLQGKEPILVAPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSP6</accession>
    <name>A0A0C1JSP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JI00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000165">
        <property type="protein sequence ID" value="KIC73521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73521">
        <property type="protein sequence ID" value="KIC73521"/>
        <property type="gene ID" value="DB41_JI00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1758"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="409" mass="46228" checksum="A02D80E7A838A3FE" modified="2015-04-01" version="1">MKVCQNTRYVFIGSHLLNAPLWAMYTLLVFIFYKDLHASPLQITLLISSKPVVAIASFYWNSFVEKRHDLLKKSIGCASVIGLLPCFSFPFIDNNWFYIFAFAVYMMASRAIIPAWMEILKIKIHAEARSKIFSVGSSINYLTSLFFPLFISRWMDHSPGIWRWGFFIAAGISLLSNFLLVTIPLPKEGPPPLNDKQNLKDTLVQPWRNFIKLMRARPDFAHFQLIFMCGGLGLMIMQPALPVFTLEVLHLSYTELVIAISVCKGIGFALTTRIWALFFNKINIYILTFLICFLATLFPIFLITASLHWIWVYVAYFVYGIMQAGSEMCWNLSGPRFARKENSAAFTGINVVLVGLRGCVGPFLGGYLGFIANSYLPLIVGGFFCLCGTGCAIYSSKKYAEKELLSKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTA0</accession>
    <name>A0A0C1JTA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JC00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000160">
        <property type="protein sequence ID" value="KIC73666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73666">
        <property type="protein sequence ID" value="KIC73666"/>
        <property type="gene ID" value="DB41_JC00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="53" mass="6218" checksum="C121B4B1A38FC2AC" modified="2015-04-01" version="1">MIKIVNELEKKHISNEIPLFLKSGVLAKIYAEPTQEGELWKKIENLQKQPWLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTI2</accession>
    <name>A0A0C1JTI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IP00150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243998.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000147.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74415">
        <property type="protein sequence ID" value="KIC74415"/>
        <property type="gene ID" value="DB41_IP00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1645"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="185"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="235"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="285"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="336"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="385"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="2">
        <location>
            <begin position="435"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="469" mass="52681" checksum="D2C73DE767E4AB0B" modified="2015-04-01" version="1">MNSLSRVCLFIDHKADYVPIFSTVTNLIDIFQKTIILLFKQKETKDPYYAHLNQKSFRRCVVLLIPVLGNILVGIWDVAHKKEVDKKIGHTAAQKNNKAFKKADSHFSNGRESVLTTVQQSDLTLQPTTKQLRRDREAPLAAVQINSLTLQPTTKEFQRDRKAPLVAVQKDGLTLRSALQGLQSDREALLAAVQKNGLALQFAPAELQNDREIVLTAVQKNGLALQYASQELSNDKEIVLAAVQHSGLALQHASLKLQNDREVVLAAIQQDDLGFQYASPELRDNREFVLAAVQHKGLVLQYASQELQNDKEVVLAAVRQFGWALQYASPELRNSRKVVFAAVRQFGWALQYANQEFRHDKKIILAAVQQNGWALQYASQKLQNDREVVVAAVQCNGRALQHASLGLRNNREVVIIAVQQDGLALEYASQKLQNDRKVVLEAVKQDGWALQYASEKLQKDEELLELSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV13</accession>
    <name>A0A0C1JV13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74910">
        <property type="protein sequence ID" value="KIC74910"/>
        <property type="gene ID" value="DB41_IB00430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5383" checksum="3D1CBDA0B2B61F66" modified="2015-04-01" version="1">MLIIGYLSETLAQRLGKIDSRLFTKANKRTKDRIAFITPSKGDYHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-12-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV46</accession>
    <name>A0A0C1JV46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative low temperature-induced protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_IB00730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385757.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74940">
        <property type="protein sequence ID" value="KIC74940"/>
        <property type="gene ID" value="DB41_IB00730"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1509"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="4">
        <location>
            <begin position="29"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="168" mass="19386" checksum="3075C3D436E8BDB1" modified="2015-04-01" version="1">MKNTYKTVPSALAVPTHLQAEASHKISQVLNPLIADAFALYVKTKSYHWHLSGPHFRDYHLLMDEQAEQIFAIIDVLAERIRKLGALTIHSIKQISQLQNVQDDNEPCIEAIQMLKRLEEENRNLAARMLAAHRVCQEYQDVATTSILEVYIDEAERRAWFLFETQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVN7</accession>
    <name>A0A0C1JVN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BN00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000234">
        <property type="protein sequence ID" value="KIC71327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71327">
        <property type="protein sequence ID" value="KIC71327"/>
        <property type="gene ID" value="DB41_BN00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7136" checksum="C9D43F900E8DD9F5" modified="2015-04-01" version="1" fragment="single">ASKIGSSNSLGKLSIDIDEIGCILFSWVVITFQHFYFLKQYKKIKEASQTNSYPYQGKTTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWH8</accession>
    <name>A0A0C1JWH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_AV00220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386920.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71582">
        <property type="protein sequence ID" value="KIC71582"/>
        <property type="gene ID" value="DB41_AV00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="704"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="788"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="830"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="872"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="914"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="998"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1155"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1197"/>
            <end position="1230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC71582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1296" mass="149462" checksum="790B36B431F0F6D5" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWY6</accession>
    <name>A0A0C1JWY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpsF</name>
        <name evidence="6" type="ORF">DB41_IB00840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385771.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74951">
        <property type="protein sequence ID" value="KIC74951"/>
        <property type="gene ID" value="DB41_IB00840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1519"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="115" mass="13506" checksum="85ED15C45669D69A" modified="2015-04-01" version="1">MSQKPKNLYEGMYIISATLSDDARHKALDRIQKGITEREGSILKIHDQGRRRLAYEIDGHREGHYFVIYFEVIPAAISELWQEYHLNEDLVRFITLQADKVMEKIEFKPLLEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX51</accession>
    <name>A0A0C1JX51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0160 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HY00270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385558.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75001">
        <property type="protein sequence ID" value="KIC75001"/>
        <property type="gene ID" value="DB41_HY00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1421"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="Met-dep_prot_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="PTHR11215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="UPF0160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="291" mass="33292" checksum="62AA5F5A188D3108" modified="2015-04-01" version="1">MNNQKLPRSVGTHSGTFHADEVTACALLLLYNLIDREQIIRTRDPQLLSQCEYVCDVGGCYDPENKLFDHHQADYQGAMSSAGMVLLYLKDQHIITPKEYDCFNAYLVLGVDAHDNGRDPQIYGLCTYSTIISSFTPIKQDADDATQDKAFFEALDFAYQYLNRILNRFNYILSCREIVSRAMEKKDDCLIFEKNIPWLELFFELGGVNHPAKFVIMPAGPHWKLRGIPPTYEDKMKVRSPLPSEWAGLLEEELKEVSGIKGAIFCHKGRFISVWETYNDALKALNYVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXL3</accession>
    <name>A0A0C1JXL3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4277 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HD00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000114">
        <property type="protein sequence ID" value="KIC75820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243923.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000114.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75820">
        <property type="protein sequence ID" value="KIC75820"/>
        <property type="gene ID" value="DB41_HD00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7617" checksum="3979431F7FC7121E" modified="2015-04-01" version="1">MCEEIGLVDLIDQAVGGQATNKHLTYGQAVKCIILKGLRFANRRLYMYSEYFEDKPIDHLLSTPAISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXT0</accession>
    <name>A0A0C1JXT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthetic protein FlhB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flhB</name>
        <name evidence="8" type="ORF">DB41_GZ00390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384990.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75875">
        <property type="protein sequence ID" value="KIC75875"/>
        <property type="gene ID" value="DB41_GZ00390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1104"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006307">
        <property type="entry name" value="BsaZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01404">
        <property type="entry name" value="FlhB_rel_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="357" mass="40154" checksum="1032AAD6B3D1F6C0" modified="2015-04-01" version="1">MGEKTEEATPKKLRDAKKKGQVAKSQDLPSAFTFIVSVYAAVALSSTLYQQLGDFTVGTFRMIATTNLEVAIPQLYYQSAIVIFIASIPLMAIVCVVGVIVNFLTVGPVFAIEVFKFDPKKFNPIQNLKAKFKLKTLIELLKSTLKLLIASYLIYQVMMKSLPILIKTVSMPMISALLVFDAFLMEVVAKIGLFFIIIAVADFIYQKKTFAKEMKMEKFEVKQEYKNSEGDPHIKGKRKQIAHEIAYSEGPAAGVKKAKAVVTNPTHLAIAIGYEREIDAAPYILVMGKDLLAERIIKLAEEYEVPVLRNIKLAHRLWESGEIYQYIPEDTYEALAEILRWVSSLNTEAQYDYIGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY78</accession>
    <name>A0A0C1JY78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GR00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC76000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243906.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76000">
        <property type="protein sequence ID" value="KIC76000"/>
        <property type="gene ID" value="DB41_GR00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="219" mass="24807" checksum="DA70CE83EEA80B13" modified="2015-04-01" version="1">MKKYFLTGLALLLPVILTLAIVAFIVNLLTDPFIHLLKAAFHYYHPANDYPWNLDQTLGLLLIIRLFILIMVVIFIIFIGFLTRTFFMYSLLSFTDNLIRHIPIINRVYKSLQDVIHPLFSSTSSSFKQVVLVPYPHESSLSIGFLTSNTLKETGEIRLKDKMAVFVPGTPNPTFGFILMFPQDKVRLIDMKVEDAFKLLVSCGIMLPSIPGSSDHAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYZ3</accession>
    <name>A0A0C1JYZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HI00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000119">
        <property type="protein sequence ID" value="KIC75651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385277.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000119.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75651">
        <property type="protein sequence ID" value="KIC75651"/>
        <property type="gene ID" value="DB41_HI00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="9569" checksum="F6404D2B8E9D2826" modified="2015-04-01" version="1">MGFISQIQESNQPEREQALQIQNSKTSLIYLSPESKSTALKVAKFVGATGILTLVAYLALCPSLDSEGKSLDFPSTLSFLNDIKGFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZC4</accession>
    <name>A0A0C1JZC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxxC_CXXC_SSSS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_KI00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72562">
        <property type="protein sequence ID" value="KIC72562"/>
        <property type="gene ID" value="DB41_KI00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="1">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="95" mass="9993" checksum="9393572C56106DB9" modified="2015-04-01" version="1">MLASGLFHGVIMPTYAYHCTSCNANHETFQKISEEPIKICLSCGKPTLQRGPGGGIGLAFKGKGFYINDYGKGASSGEEKASGPDNCACGKNKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZH6</accession>
    <name>A0A0C1JZH6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">malQ</name>
        <name evidence="8" type="ORF">DB41_GZ00450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75881">
        <property type="protein sequence ID" value="KIC75881"/>
        <property type="gene ID" value="DB41_GZ00450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1111"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="535" mass="62571" checksum="B651BD84FB1A44CF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZP3</accession>
    <name>A0A0C1JZP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluD</name>
        <name evidence="5" type="ORF">DB41_KD00070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386289.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72707">
        <property type="protein sequence ID" value="KIC72707"/>
        <property type="gene ID" value="DB41_KD00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1865"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="18"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="315" mass="35950" checksum="097551925C168A40" modified="2015-04-01" version="1">MKNDESECVIIREEEEGERLDKILSQRFLGVHSRTYFQYLIEQGRIFVNGEVVKKRYRPLVDDEIHIHYILTPEIGLQPEAIPLNIIYEDNDLIVVNKPAGMVVHPAPGHSTGTFVHALIYHCQNLPKNQVEELYPRPGIVHRLDKDTSGLLVAAKTTEAHTRLIEMFSNREVYKEYLAICVGNPGSQEIRNFIGRHPVFRQKMKVLEEGGRLAISVCETKNHSAPFSLVQVNLKTGRTHQIRVHLQYVGAPILGDPIYGNLPINKKYGVNRQLLHAHILQFKHPIKGHLLSFKADIPSDMRVWVEKLMKQAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0F2</accession>
    <name>A0A0C1K0F2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Tetratricopeptide TPR_2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_FG00010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000068">
        <property type="protein sequence ID" value="KIC76640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76640">
        <property type="protein sequence ID" value="KIC76640"/>
        <property type="gene ID" value="DB41_FG00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="104"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="146"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="188"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="398"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="482"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="531" mass="59569" checksum="4863963C4FAA60BD" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Q0</accession>
    <name>A0A0C1K0Q0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_ET00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243815.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76740">
        <property type="protein sequence ID" value="KIC76740"/>
        <property type="gene ID" value="DB41_ET00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025159">
        <property type="entry name" value="AbiEi_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13338">
        <property type="entry name" value="AbiEi_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="256" mass="29450" checksum="400E33B9CBF40CCF" modified="2015-04-01" version="1">MGVAQAHTALQIGKFHHLYYLMQILLKSKFCLIPESTGLTLRGFSCIKPLNIRGFMKTPESELFEIAETQQGYFTFQQATAAGFSDKNHAYHIKTGDWVKAFRGIYRLAKYPVGEREELVLWFLWSRNRSNVPQGVYSHYTALDLYELSDNMPSKLHMTVPLGFRRMAKIPEILILHRDNLHTDEIVMKQGYKVTTPLRTLIDVLEDSVLSEDLLMQAVQDAKKKGLITKYAIEANQRYPAKVAERLLKMMEEAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0R5</accession>
    <name>A0A0C1K0R5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MAF_flag10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JT00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000176">
        <property type="protein sequence ID" value="KIC73067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73067">
        <property type="protein sequence ID" value="KIC73067"/>
        <property type="gene ID" value="DB41_JT00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1820"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002826">
        <property type="entry name" value="MptE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01973">
        <property type="entry name" value="MAF_flag10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAF_flag10" evidence="1">
        <location>
            <begin position="7"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="530" mass="59261" checksum="8C1D38AC1915D3AC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0R8</accession>
    <name>A0A0C1K0R8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">accB</name>
        <name evidence="4" type="ORF">DB41_EO00130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76760">
        <property type="protein sequence ID" value="KIC76760"/>
        <property type="gene ID" value="DB41_EO00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.545"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="3">
        <location>
            <begin position="78"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="154" mass="16797" checksum="A3AEE8F73A73E5B6" modified="2015-04-01" version="1">MGAMGRTGTKRVTIKKEGFEIEIERYDGGTIKVPESMFESPEETFNKTDEALRRANISVASLAVPPGQAVEHKEDANTFFVTSPMVGTFYNTPSPEEPPFVKVGSKIDKNSVVCIIEAMKVMNEIKAGATGTVAEVLVENGHPVEFGTKLFRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1K1</accession>
    <name>A0A0C1K1K1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76591">
        <property type="protein sequence ID" value="KIC76591"/>
        <property type="gene ID" value="DB41_FI00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="8062" checksum="F5A878DF8B86FC07" modified="2015-04-01" version="1" fragment="single">MIRKPYPSDLNNQEWQVLEPIICKKKAGKPPKHARREMLNAIFYVLRTGCQWTDLPHDLPPWKSVYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K219</accession>
    <name>A0A0C1K219_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_EY00270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76716">
        <property type="protein sequence ID" value="KIC76716"/>
        <property type="gene ID" value="DB41_EY00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF294" evidence="5">
        <location>
            <begin position="268"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="DUF294_C" evidence="6">
        <location>
            <begin position="508"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="748"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="832"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="874"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="916"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="958"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1042"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="203"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1163" mass="132732" checksum="92975E76878A06BD" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2K2</accession>
    <name>A0A0C1K2K2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DT00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76911">
        <property type="protein sequence ID" value="KIC76911"/>
        <property type="gene ID" value="DB41_DT00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="102" mass="11330" checksum="ED88F2AA957FB889" modified="2015-04-01" version="1">MEKIYLNLLLLFLTGCMAPIMTTSGFEGIVPGTSITTIEAQFGSPYEVNRLPNGLQEYIYIQRTSLSSSAVDQLSYILYVSQGKVISKCLKSDSPALFINYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2L8</accession>
    <name>A0A0C1K2L8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative uridylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CO00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243737.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77255">
        <property type="protein sequence ID" value="KIC77255"/>
        <property type="gene ID" value="DB41_CO00240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.58"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070569">
        <property type="term" value="F:uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="PTHR11952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="451" mass="51383" checksum="16FC5DE7D55C005F" modified="2015-04-01" version="1">MNYDRAIAKLNSIQQLHLLNYWHELNEAEKNLLLQQIENLDIDAFHEQQAVINARFLCDISVDPFLDYQKVGSLEDALLGKEAIEQGRLGCLIVAGGQGTRLHLEGPKGLYPISLIRHKSLFQLFSEKIVAASKLALHPLQAAIMTSPLNHERTLAYFKTHAYFQLRKEQLDFFAQPMLPFLDEAGNLFLEKKGLLAEGPNGNGACLHQFWEEGLLAKWKKMGIEHLNFVMIDNPLADPFDAELLGMHIRNQNDITIKCTLRADPEEKVGVIVKQQQKVQVIEYTEFPESERYARLSDGSLKHPCANISLFCISLSFIEKICDKKIKMPLHALYKKTPSLIDSSQKGWKFEHFIFDIFPLADKVQALLCPRERCFAPLKNLSGQDSPASVQDALQARDRQLYEELFSKKAPLVPFELAQDFYYPVPSYVDQWKKHALPPEGYFGDIGCLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3C3</accession>
    <name>A0A0C1K3C3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IY00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73812">
        <property type="protein sequence ID" value="KIC73812"/>
        <property type="gene ID" value="DB41_IY00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="21720" checksum="F93932ACD8A61F21" modified="2015-04-01" version="1">MSRSGWFWQTLASLGKLGLLFYWIKINSLSRILRMNEAFKIYVEQLRDGHAEAIVEKLGPEFLDIHEKELSFVDPVVVEGEAYLAENDLVLHFDIQTFATLPCVICNEAVKTPIKLENFYHTVPAEEIKSGIYNFQEMLRENILLTAPFFAECNNGQCPHRGELNKFFRDSDSPDGNSEDEGYRPFAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K549</accession>
    <name>A0A0C1K549_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IP00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74422">
        <property type="protein sequence ID" value="KIC74422"/>
        <property type="gene ID" value="DB41_IP00220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1652"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="82" mass="9091" checksum="945D27C54D9196BA" modified="2015-04-01" version="1">MVLAAVQQNGLALQYAGEDFKNDKEVVLAAVQQQGCSLQYASQALRNDRKVVMAAAKQNGMALRYASEQLQKDKEFLKLCNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K848</accession>
    <name>A0A0C1K848_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UPF0758 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_HO00050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385382.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000125.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75357">
        <property type="protein sequence ID" value="KIC75357"/>
        <property type="gene ID" value="DB41_HO00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1306"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="109"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="236" mass="26378" checksum="A5FE04707484EACB" modified="2015-04-01" version="1">MNKPLEGYTIQQMPIEERPRERLLQHGPEAISSAELIAIVLGSGTKGCSVLRIGQELLMRFGTLQKFAEASIEELQQIKGLGLAKAIQLKAALNLGLRASKQAIDQRFRIVTPLHAYNYIKDELEYAKVEHIVVILQDRKGYVLSHHLVALGTLSHAPIHPRDVFHPVIRHQAASLILVHNHPSGDPTPSPEDLEVTQSLIQAARLVDIAINDHLIIGRGRYISLRQNHKNLWDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9J4</accession>
    <name>A0A0C1K9J4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GZ00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75852">
        <property type="protein sequence ID" value="KIC75852"/>
        <property type="gene ID" value="DB41_GZ00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6069" checksum="2676CD2D20E2596D" modified="2015-04-01" version="1">MDVGFSAENMALIRRLAANIIRTMDSGRRIADARRNATYAPNYLRGLLGKVFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9K3</accession>
    <name>A0A0C1K9K3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="6">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="6">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="6">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">msrAB</name>
        <name evidence="6" type="synonym">msrA</name>
        <name evidence="8" type="ORF">DB41_GZ00260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 6">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384972.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75862">
        <property type="protein sequence ID" value="KIC75862"/>
        <property type="gene ID" value="DB41_GZ00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1091"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="7">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="284" mass="32423" checksum="21E3E0293DD1076F" modified="2015-04-01" version="1">MERYHALDSYEESIILKKGTEKPGTGKYYHFAEGGIYLCRHCDAPLYMSSDKFPSQCGWPSFEDEIKGAVERKLDADGERTEILCRRCSGHLGHLFIGERLTRKNQRHCVNSTSLTFNPAFTQEGYARAVFAAGCFWSVEHLFKKVEGVVSTTVGYIGGSTVHPTYQEVCTGMSGHAESVEIIFDPEIVTYETLAKLFFEIHDPSQHNRQGPDRGEQYRSAIFYLSEAQKKIAENLVIKLEKKGIKVATRLLPASFFYPAEEYHQDYYDKVGKEPYCHVRVKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9K8</accession>
    <name>A0A0C1K9K8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">dnaJ</name>
        <name evidence="10" type="ORF">DB41_GZ00310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75867">
        <property type="protein sequence ID" value="KIC75867"/>
        <property type="gene ID" value="DB41_GZ00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1096"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="163"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="176"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="193"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="215"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="229"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="163"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC75867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="401" mass="43720" checksum="3695EB509350FBF3" modified="2015-04-01" version="1">MFFLLKDMHSQDIYVSIMADYYETLEIPRTATADEIKKAYRKKAIKYHPDKNPGNAEAEKRFKEISEAYEVLSNDKKRQTYDRYGKEGLGAAAGAAGGGFSGFSSVDEALRTFMGAFGGMGGESIFESYFGGNDFGGGSAQMRRQGASKRANITISFLEAAKGVDKELAINNYVTCKTCHGKGTPSSKGKKKCPRCHGAGQVYEQKGFFSMSMACPQCHGEGEIITDPCKDCRGEGLIKEKQHVKIHIPAGVDSGMRLKMSGYGDAGHGGGPAGDLYVFINVEPHEIFEREGNDVLLDLPISFTEAALGCKKDVPGLYGHTCRITIPEGTQNGKVFRLRNEGFPSVHGQGKGDLLVKIFVETPTQLSEKQIKLLKEFSSLQGPANLPKSNSFLDKIKSIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9X6</accession>
    <name>A0A0C1K9X6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GV00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000107">
        <property type="protein sequence ID" value="KIC75947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75947">
        <property type="protein sequence ID" value="KIC75947"/>
        <property type="gene ID" value="DB41_GV00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="375" mass="44471" checksum="6A741B8A13036114" modified="2015-04-01" version="1">MERHTKSNRKENNFYADFATRAKFNDYLREEQFIGKKYRKNNIKKKMTQEKMIKLEKYLAGLLNIWEGQVNPNIPLKPILNRPNFNRINLFNPIVRPPKFLPILADNKTTATTTPLQEKIIETNKLNTVYQEMLKDLELLHYASNLRTYHHIKQTIHGFFKIYSNRSQLWDYYLKHSSYDSATYIHDLTGVYLHTEQTKDTIKFLIKTSAKLFFNTYQKAKANARLKEFFNQAFSSYNYCLEARYTYLCDKWVASESQSACLEKEPLAEIMKIDPHITKEKNIEKLVEIFEDLQARQYAKDHGIIINKAWNKPEGPKYQKVFKDNKFNSYYNVHNFEQALLVEMKIVGQKCMNGTYTEKEVKELIQKMVDADIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAV4</accession>
    <name>A0A0C1KAV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76262">
        <property type="protein sequence ID" value="KIC76262"/>
        <property type="gene ID" value="DB41_GL00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.935"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="472" mass="53843" checksum="728F3EDCB92346B0" modified="2015-04-01" version="1">MRRSICYCEPASAQAGEVNNWKFVYTSANSLPKGTRLKFDMLSNGRDIDWQIPSSNVKKITNIIYGELESGKIISAKEVSSAAHFTPDFEFILPSALEAGSNFTIVIGTTDIKKANKEGNRAQTNSQRRRPFNIYIDPTGQGNYGEPEVFCLDIKGNTLCSIRVVAPSYVTRNKRFDVIVRFEDQYGNLTSDAPDETLIELSYEHLRENLNWKLFVPETGFIALPNLYFNEPGIYTIRLLNTYTQQVFQSPPIKCFADNNKSVFWGILHGESERIDSTENIENCLRHFRDDKGMNFFGASPFESQEETSNEMWKLISQNLLEFDENDRFTTFLGTQWSGIPEEEGTRQIVFTKDHKQPLRKKDAKYSTLKKIYKSFSPKEIISIPTFTMGKGYEYNFKNFDPDYERVVEIYNAWGSSECLKKEGNLRPIQSHGKVGVQESAEGSIQKALLNNCRFGFVAGGLDDRGIYAPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAZ8</accession>
    <name>A0A0C1KAZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">mutS</name>
        <name evidence="10" type="ORF">DB41_GK00160</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243888.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000096.1"/>
    </dbReference>
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        <property type="gene ID" value="DB41_GK00160"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="9">
        <location>
            <begin position="702"/>
            <end position="718"/>
        </location>
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    <feature type="binding site" evidence="7">
        <location>
            <begin position="628"/>
            <end position="635"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022840"/>
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            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="847" mass="95704" checksum="E57C0401A984D6C4" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBA0</accession>
    <name>A0A0C1KBA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
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            <taxon>Chlamydiae</taxon>
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            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000089">
        <property type="protein sequence ID" value="KIC76427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="KIC76427">
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        <property type="gene ID" value="DB41_GD00050"/>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002135024" evidence="1">
        <location>
            <begin position="21"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="844" mass="98755" checksum="7932ADA9517FD944" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBI8</accession>
    <name>A0A0C1KBI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
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            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76507">
        <property type="protein sequence ID" value="KIC76507"/>
        <property type="gene ID" value="DB41_FX00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="5682" checksum="C3934D458BEC648A" modified="2015-04-01" version="1">MLKKTFKALEKMRRPGSSARSFAAISEDRLPKRRCTALKEALEETFPLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBJ4</accession>
    <name>A0A0C1KBJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FX00210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76512">
        <property type="protein sequence ID" value="KIC76512"/>
        <property type="gene ID" value="DB41_FX00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="319" mass="35975" checksum="974078453FA43BE0" modified="2015-04-01" version="1" fragment="single">MHPISSASVESLPNELLLPILEACVVPSLFRVCKRWHHLLASEVMPRLYKQIGKMHVPQGNVKEQALIVDRIYKLEEKLSEAAKVNAIFRQIFTLASYLSPLKSKGDEELSETAKVNVIFRQIFNLASSFFSLKSKGQIEEKKSFTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLQKKGELLREWIEENCKNIEAVDLSGVGLTYLPSEICQLSKLQTLDLNQNQLVSLPAEIGQLSQLRALVLRQNQLVSLPAEIGQLSQLRTLNLRENQLTGLPKEIGQLSRLRVLYLKQNQLIALPVSSVMVGDPGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC16</accession>
    <name>A0A0C1KC16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FD00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76642">
        <property type="protein sequence ID" value="KIC76642"/>
        <property type="gene ID" value="DB41_FD00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="7353" checksum="0157282DC49F5A74" modified="2015-04-01" version="1" fragment="single">NTFNYTHFTGLFLFFFIYKNIFLKDINFYFFYYIEVFKVFNYNIFHKYRLITNMEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC53</accession>
    <name>A0A0C1KC53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FB00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384045.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76677">
        <property type="protein sequence ID" value="KIC76677"/>
        <property type="gene ID" value="DB41_FB00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="63" mass="7095" checksum="15524449E536130E" modified="2015-04-01" version="1">MNLTSAIHRLASLLVGKNRRTGNFLFSAFLASKFSKTYLRSPSEIKTRNLGNLQGFLKTRKPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC72</accession>
    <name>A0A0C1KC72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76702">
        <property type="protein sequence ID" value="KIC76702"/>
        <property type="gene ID" value="DB41_EY00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="185" mass="21711" checksum="07025799FC1BDE22" modified="2015-04-01" version="1">MKMIQAILASDFNRLGYSIKSLAKNLLDKFTSFLAERKRTLSTLFLINHSSSFIEKKKNCKVFCFSYSQKEIKLSTFFLLVFPFLNFIWKASNYYFPHKAFLFAGEVLGPNRSTLHAFLKLVSTLKLLKIRDVRLMEQGAYLSTCFHPVISWPPKNIKIVQDLWVLKNRHYYCLEEKNYKKGDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC88</accession>
    <name>A0A0C1KC88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76717">
        <property type="protein sequence ID" value="KIC76717"/>
        <property type="gene ID" value="DB41_EY00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="4785" checksum="1E5224411E6AB48F" modified="2015-04-01" version="1">MNLINHVRMIRAARELASLEKERAGAKAAFQPSRLKSCFKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCF3</accession>
    <name>A0A0C1KCF3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">dapF</name>
        <name evidence="10" type="ORF">DB41_EJ00020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383847.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76772">
        <property type="protein sequence ID" value="KIC76772"/>
        <property type="gene ID" value="DB41_EJ00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.517"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="193"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="204"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="269" mass="30097" checksum="9D03BAFB18D7319B" modified="2015-04-01" version="1">MLFTFSKYSGCGNDFILFDNRTSKLSALTPNLIQKLCARQKGIGADGVILLETSQKAHYKMRIFNADGSEAEMCGNGIRCLFKFIQECGIQEEWLNIETLFSTLKVSSEDEDVAVQMGSPSEIRWSLNLFPWTIHYLDTGVPHAVIFTEKLDLLDLNECGRTLRFHPLFAPRGANVNFVQIDDQGILHVRTYERGVEQETLACGTGATAAALAAAKLYELKGPLTVKVRSEDFLRIDFEYNKGCFTKVRMIGPAKLVFKGTVNLEHALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCF9</accession>
    <name>A0A0C1KCF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative tRNA/rRNA methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trmH</name>
        <name evidence="2" type="ORF">DB41_EJ00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76777">
        <property type="protein sequence ID" value="KIC76777"/>
        <property type="gene ID" value="DB41_EJ00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.522"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="101"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="250" mass="28850" checksum="8E7127CB507ECD49" modified="2015-04-01" version="1">MFTKRKFLSFSMEKQHKKCAELLLAIYKDKIAFQPIEGMLAHYHELQEWMQREDKLSSDAKEIANRYHYHLKLANRKVREHHLLPSIRQGDRAQGEKIWPISIYLDSLRSAHNVGSIIRTTEAFALGAIYFSEHTPYINNLQVQNASMGTFQWIECHPSCKVTDLPRPLIVMETSPQATSLYNFIFPEVFTLALGNEEYGCSDEVLRVADHLIEIPLRGRKNSLNVANAFAITASEIYRQKKEDHGQKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCY8</accession>
    <name>A0A0C1KCY8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_DS00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76922">
        <property type="protein sequence ID" value="KIC76922"/>
        <property type="gene ID" value="DB41_DS00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.376"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="482" mass="51788" checksum="5646F6E136E8DE19" modified="2015-04-01" version="1">MIPDILLIPENMLLLIFLLLAGFYMAWSIGANDVANAMGTSVGSGALSLKTAVVIAALLEFSGAFFFGSHVSDTIQTGIIDSALFAYEPRILVYGMLASLLAAGIWLQIASYFGWPVSTTHCIVGAIVGFGIVVGGLEAIQWENVLFIITSWVISPILGGIISYFIFNILRKKIFYTPNPIRSAQKITPMIVFLTVTVMGLILVFKGLQNLNLEFTFLEALIFSAFLGTIGSFISYLLLRNISAPTRCQQPVCNAETTLSLDKARKHLLRARETVSGNEMHYHLSILLNEVDNVSTTIKKSSDGEVHKSEYATVEKIFGYLQIMSACLMAFAHGANDVANAIGPLSQGIQVLINNTVITTSTTPVWALALGGVGIVVGLATWGWRVIETIGKKITELTPTRGFAAEFGAATTVVLASRLGLPVSTTHTLVGSVVGVGLARGLEALDLSMTRDIMISWLVTVPTGALIAVGFFNAIMYLITII</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE66</accession>
    <name>A0A0C1KE66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="9">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">alaS</name>
        <name evidence="13" type="ORF">DB41_CO00310</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383130.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77262">
        <property type="protein sequence ID" value="KIC77262"/>
        <property type="gene ID" value="DB41_CO00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.65"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="12">
        <location>
            <begin position="1"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="726"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="565"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="569"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="667"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="671"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="882" mass="99018" checksum="E454111D69B7B030" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3K9</accession>
    <name>A0A0C1H3K9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386540.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72114">
        <property type="protein sequence ID" value="KIC72114"/>
        <property type="gene ID" value="DB41_KU00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="84" mass="9340" checksum="DD63B0EE60C077BE" modified="2015-04-01" version="1">MMNIAENNLIRFINISKKKDGIFANFKVKGLRGGTSFSASISVDISAAEVDPTDPLEKIIEHCARMAVRDFKKTEMQFEGMTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H3S0</accession>
    <name>A0A0C1H3S0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sensor protein KdpD</fullName>
            <ecNumber evidence="6">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">kdpD</name>
        <name evidence="6" type="ORF">DB41_KR00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386509.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000197.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72179">
        <property type="protein sequence ID" value="KIC72179"/>
        <property type="gene ID" value="DB41_KR00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2033"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003852">
        <property type="entry name" value="Sig_transdc_His_kinase_KdpD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02702">
        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="429"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="668"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="883" mass="99663" checksum="F0FB6DA9A9F3517E" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H408</accession>
    <name>A0A0C1H408_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein TolB homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tolB</name>
        <name evidence="3" type="ORF">DB41_KP00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386457.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000195.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72274">
        <property type="protein sequence ID" value="KIC72274"/>
        <property type="gene ID" value="DB41_KP00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1999"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="458" mass="51242" checksum="350F5B8835175D9E" modified="2015-04-01" version="1">MTHLKYYFIILFLFLVFKQNLSALANEDNEKIVVRLATESKLMPLYLAPFYQENPAFTAHYIQQLEQVLQFDLNHNGMTFTLKNESKAPVGNFLDAVNSSSWKSLNVYYVLKILIKDNQMSARMLSMSSDHEKSVNNIPLSGDLSQDRRQIHRLADSLHKSLFGSEGIASTRIIYTCKTSHGLKSIAEVWEADYDGANARQITHENSLIVTPTYIPPQQGHASGSIMYVSYRAGQSKIYIASLKDGVGRRFSLLKGNQLMPAIAKQRDKVAFICDYTGNPDLFLQTFDPEKGAIGKPQQIFSTYLATQGTPTFSPDGSKIAFVSNKDGSPRIYVIDIPAPGASLKNIKALLISKSNRENTAPAWSPDGSKLAYCAKSQDTRQIWIYDFDKKQERQITKGGGHKENPTWAPNSLHLVFNSAGNNSSELYLINLHQPEAVKISSGEGLKRFPAWEPKFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8S8</accession>
    <name>A0A0C1H8S8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BQ00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000237">
        <property type="protein sequence ID" value="KIC71283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71283">
        <property type="protein sequence ID" value="KIC71283"/>
        <property type="gene ID" value="DB41_BQ00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="448" mass="50812" checksum="CEC2A03B8C3B7E9D" modified="2015-04-01" version="1" fragment="single">MEFKWKTEEKRGLTLANYSSYLVNINRLLLWKKLPGGEEYLNREEIKHLPLEKKGELLRDWIEENCKNITTLDLSRLSLTYLPPEIGQLSQLQTLDLRENQLASLPAEIVQLSQLRELYLNQNQLTALPAVISQLSQLQLLNLNQNQLTALLTEIGQLSKLTRLDLNQNQLTALPAVISQLSQLQLLDLNQNQLTALPTEIGQLSQLQGLWLSGNRLTALPAEIGQLPQLRGLNLNQNQLTSLPAEIGQLSNLQYLYSNQNQLTSLPAEIGQLSQLRGLYLNQNQLTSLPTEIGQLSYLLQLHLSQNQLTALPAEIGRLSRSRLEFLELNQNQLTTLPAEIGQLFQLRVLDLNQNQLTSLPEEIWQLFQLRGLNLNQNKLTSLPAEIRRLSQLQVLYLNQNQLTSLPTEIGQLSELQTLKLNQNQLTALPTEIGQLPQLQGLYLNQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HA05</accession>
    <name>A0A0C1HA05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AS00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000215">
        <property type="protein sequence ID" value="KIC71668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71668">
        <property type="protein sequence ID" value="KIC71668"/>
        <property type="gene ID" value="DB41_AS00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="613"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1084" mass="124146" checksum="9E8DA0B62F34DD08" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBF8</accession>
    <name>A0A0C1HBF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72108">
        <property type="protein sequence ID" value="KIC72108"/>
        <property type="gene ID" value="DB41_KU00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6107" checksum="B6CECE00B3FD9BAB" modified="2015-04-01" version="1">MLIIRNIKFKSLYIDSLVPSGRGRLKLKGGQALKNKRRDASKVVKGLGVGVKASQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBL1</accession>
    <name>A0A0C1HBL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KR00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72178">
        <property type="protein sequence ID" value="KIC72178"/>
        <property type="gene ID" value="DB41_KR00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="135" mass="15325" checksum="FC6C31F13957A89B" modified="2015-04-01" version="1" fragment="single">MFAFSFNPIATHTNLEGTFTFFEKAGSEKIYAEVPKQEGLFPVSISPKVRTEALTYLSSAAKIKRLLQGFFVQPRYQAEKNEVTLEWSSPKIETWKRKAMLRLPSDAISICRADGKISYAIGDTVTTWDWATDTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBV1</accession>
    <name>A0A0C1HBV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IB00320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385714.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74899">
        <property type="protein sequence ID" value="KIC74899"/>
        <property type="gene ID" value="DB41_IB00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003744">
        <property type="entry name" value="YhhQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34300">
        <property type="entry name" value="PTHR34300"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02592">
        <property type="entry name" value="Vut_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="176" mass="19962" checksum="2B8D550E3FEAA653" modified="2015-04-01" version="1">MFSIQFAYLAMIAIVTSCNFLVQFPINDWLTWGSFTYPLSFLVTEVNNCLHGPRVAKRVVYVGFMLAFLLSIWLSTPKIACASGLAFLISQLLDISIFASMRKRTWWFAPLFASIGASFVDTCIFWSLAFWGEPVPLMNWALSDLSIKILFDFVLLIPFRLAIQKATNPLRESLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBZ0</accession>
    <name>A0A0C1HBZ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Glycine--tRNA ligase beta subunit</fullName>
                <ecNumber evidence="9">6.1.1.14</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">Glycyl-tRNA synthetase beta subunit</fullName>
                <shortName evidence="9">GlyRS</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Glycine--tRNA ligase alpha subunit</fullName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">Glycyl-tRNA synthetase alpha subunit</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">glyQS</name>
        <name evidence="8" type="synonym">glyQ</name>
        <name evidence="9" type="synonym">glyS</name>
        <name evidence="10" type="ORF">DB41_IB00670</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243975.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74934">
        <property type="protein sequence ID" value="KIC74934"/>
        <property type="gene ID" value="DB41_IB00670"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1502"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1018" mass="116113" checksum="B741D25F8DC16524" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HC85</accession>
    <name>A0A0C1HC85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">typA</name>
        <name evidence="2" type="synonym">bipA</name>
        <name evidence="4" type="ORF">DB41_HY00400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75014">
        <property type="protein sequence ID" value="KIC75014"/>
        <property type="gene ID" value="DB41_HY00400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1433"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="6"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="18"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="600" mass="67719" checksum="0401734EB3945226" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCN9</accession>
    <name>A0A0C1HCN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium-transporting ATPase, P-type 1</fullName>
            <ecNumber evidence="5">7.2.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mg(2+) transport ATPase, P-type 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">mgtB</name>
        <name evidence="16" type="ORF">DB41_KI00120</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Mediates magnesium influx to the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + Mg(2+)(out) = ADP + H(+) + Mg(2+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10260"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.14" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56784"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
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        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
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        <location>
            <begin position="113"/>
            <end position="130"/>
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    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="281"/>
            <end position="299"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="311"/>
            <end position="335"/>
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        <location>
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            <end position="785"/>
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        <location>
            <begin position="836"/>
            <end position="857"/>
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    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="863"/>
            <end position="885"/>
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        <location>
            <begin position="37"/>
            <end position="110"/>
        </location>
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        </source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="KIC72568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="893" mass="99910" checksum="79B3FB19383C4E13" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HD44</accession>
    <name>A0A0C1HD44_9BACT</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name type="scientific">Neochlamydia sp. TUME1</name>
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        <lineage>
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            <taxon>Parachlamydiaceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <end position="58"/>
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        </location>
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    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
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            <end position="545"/>
        </location>
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    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="546"/>
            <end position="578"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="613" mass="67436" checksum="B39AF3FC5C26038F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDH4</accession>
    <name>A0A0C1HDH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HL00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
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            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385318.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000122.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75469">
        <property type="protein sequence ID" value="KIC75469"/>
        <property type="gene ID" value="DB41_HL00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="95" mass="10560" checksum="A1C4D310678E5498" modified="2015-04-01" version="1">MEYEVPHALEAAISIFIHPIRFKKHLLSNNPLTYTLCQEKSNAYPSPGRFDRRVVSGLLVGVGCYFYAGLAVEAGCLFFSPRSERHGGAMEILLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HDH7</accession>
    <name>A0A0C1HDH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase IS630</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HL00070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000122">
        <property type="protein sequence ID" value="KIC75474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75474">
        <property type="protein sequence ID" value="KIC75474"/>
        <property type="gene ID" value="DB41_HL00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="3">
        <location>
            <begin position="180"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="295" mass="33317" checksum="8853A072A20EE50A" modified="2015-04-01" version="1">MFVAAYHTIKELNALAKRQPSARYSHPLRAIAMAMEGESAYQIGKALGYSTSTIQKWIRRYNHYHLERLQDNRPITTERKRAVMPQRKKAFSGRAERRPSPEESSSLSPLHDLPFTVKEELDKSLALPEGSKILGYPHYTTLTSRIPGYQANKKEYTGFKKVPEAIEALSNQFPKHKIEIWFEDEAKLGPPPAYRQGAAKKGKRPKVPKSIAYPTLYIATAICPALEKAEGLIFPFLNSKAIEHLLEQVNQSLPVSSHALLILDRAPYHVCKKLRIPPKVHLFFLSPPCPKAPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE64</accession>
    <name>A0A0C1HE64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">xseA</name>
        <name evidence="9" type="ORF">DB41_HH00020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385191.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75709">
        <property type="protein sequence ID" value="KIC75709"/>
        <property type="gene ID" value="DB41_HH00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1199"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="8">
        <location>
            <begin position="11"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="127"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="451" mass="51090" checksum="05D9BAB7CF6F05DD" modified="2015-04-01" version="1">MHLPASEPVVLSVTQLTQAIKLSLEGTFPNVWLQGEISNCKPHSSGHIYFSLKDAHAQISAIIWRQEAALLQSPPKDGMQVLVRGAINVYPTRGNYQIVIYEMKPVGLGELLIKLEELKQKIHQLGWFRKEHKKPLPRMPNRIGVITSPTGAAIQDILNILTRRSGGLNLLINPVRVQGLEAAQEIAQAIHFFNEHDLVDVIIVGRGGGSIEDLWCFNQEIVAEAIFYSRIPIISAVGHETDHCIADYVADVRAPTPSAAAEIVIADKLEQLKHLEQIKRRLTQSISHKVFLSRQRLSAFLKQPMLSSPYYLLGPWIQRLDDNRQQLDYLIKQKICRLHLILDSSNKRLQTLKPSSQITYLQEKIKYWDKNIYHQMSHIIDSKKEQLESISVALHLINPKNLLTKGYSILFSEKDNSVITSVTNIHKNQDLRIYLSDGEVLSTVKEIKASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HED6</accession>
    <name>A0A0C1HED6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="6">RF MTase</shortName>
            <ecNumber evidence="6">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">prmC</name>
        <name evidence="9" type="ORF">DB41_HE00100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385085.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000115.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75794">
        <property type="protein sequence ID" value="KIC75794"/>
        <property type="gene ID" value="DB41_HE00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1144"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="106"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="188"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="282" mass="32232" checksum="F7416917DC52B6E3" modified="2015-04-01" version="1">MNTVQDILNLSTGYLAQKGIKNPKLQAEYLLCDALQLSRIQLYQQFDRPLEEQELKICRERLARRAKGEPLGYIHGKMDFYGCQISVNKDVLIPRQETEILVDKIVKQLEQVEVCGLHLWDVCCGSGCIGVSLKKKFPLLEVTLSDISPQALELAKKNAKENQVEVHFLQGDLLKPFEGKKVDYLVCNPPYIAEYEFAGLDYEVRDFEPRLALISGPTGLEMYQRLSEQMKACLAPLAKVWLEMGSSQGPSLCKLFSQSGWRNYRVDKDWAGLDRFFFLENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HET4</accession>
    <name>A0A0C1HET4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GV00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000107">
        <property type="protein sequence ID" value="KIC75949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75949">
        <property type="protein sequence ID" value="KIC75949"/>
        <property type="gene ID" value="DB41_GV00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6758" checksum="378FBE15A8530DA8" modified="2015-04-01" version="1">MVVDKKSRKVICTAFSNGKKHDYKLFKESKVRVCREHTVDVRNYMKDEGKWLLEVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEY0</accession>
    <name>A0A0C1HEY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GR00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384842.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000103.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75994">
        <property type="protein sequence ID" value="KIC75994"/>
        <property type="gene ID" value="DB41_GR00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="736"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1743"/>
            <end position="1777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1780" mass="204905" checksum="BA1CF1C2D39FC7E3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFC8</accession>
    <name>A0A0C1HFC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GN00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000099">
        <property type="protein sequence ID" value="KIC76094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243897.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000099.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76094">
        <property type="protein sequence ID" value="KIC76094"/>
        <property type="gene ID" value="DB41_GN00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.965"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="88" mass="10162" checksum="34034F8671A6E76B" modified="2015-04-01" version="1">MENNQLTTLPAEIGQLSQLQTLLLNNNQLTTLLAELRQLAHLQMLYLNDNRLTNVPAELGQLTERLDLNLKENPLQSIPDEIKQRFRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFW3</accession>
    <name>A0A0C1HFW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HET-D protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">het-d</name>
        <name evidence="5" type="ORF">DB41_GL00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384737.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76269">
        <property type="protein sequence ID" value="KIC76269"/>
        <property type="gene ID" value="DB41_GL00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="204"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="246"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="465" mass="52628" checksum="B84F833C66AE3E78" modified="2015-04-01" version="1">MIPSPFSPAKILSITDQANFQHSLINTVNNLDSLPNELLLHIFSFLSVKDSSVAHRVNTKWYQLFSEKMHWRHLFKQNFPHLYSLSEKLEIHPKDQLAAQVNIKAGRVQRILHIGGKRNDLGSGYLLCSADGQLVATLNYFDSFGFKPCIWEVKAGKLLYTLENFQKKKVLMAFSPNNEWIATGSDDHTPFIWNIKTGEFLRALKGHKQDITTLVFSSNSQLIATSSADHAARIWRVETGECLHTLQGHLLSVTSLAFSPDDKLIVTASDDHTVRLWEIESGKCIWELERLQPVVRVAFSPNGRWIVTNTAPPTYLQMEADGFIKLWNARTGAYKHTFGKNLAQNANFLFSPDGKWLVVSEYDDHSICLWEVETGKCMHTWAGLIGNSHVAFSPDSNLIAIAIGVYDKSIHFWEIETGTYLYTLPIDVFYCASIKFSPNAGHFFVNNQMFDFFPQEGAILPSNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGK6</accession>
    <name>A0A0C1HGK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sucB</name>
        <name evidence="7" type="ORF">DB41_GA00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384432.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76479">
        <property type="protein sequence ID" value="KIC76479"/>
        <property type="gene ID" value="DB41_GA00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.805"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="2-oxoacid_dh" evidence="5">
        <location>
            <begin position="156"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="377" mass="41989" checksum="0E9D41D2279AC131" modified="2015-04-01" version="1">MKVEFKVPSMGESIFEATVVSIIRPSGSQVGFEDEILELETDKVNQMVYAPQKGVIHFNIQLHDKVTIGQVLGYIDTEAAAKSLELGSPPQQFLPSLPATVVNPKESFKSMRYQKEDFIKELKEEGQKRSLPSLSEQQSLAWSFHPQQSHGNKDFTQKASVSQVAQVENTATMLTIFNEVDLSQIIHLRDRYQKSFIKKYEIELGLISFFVKACVAALPQFPSIHSYLKEEQSVQDSSYEMGIAVETEQGVVVPLLCQGDKLSYAEIERTIEKLTHQAYEGSLSVGDLHTGSFAITDAGLYGSMFSTPLLTGNQRAILALHNIIKRPIVVDDQITIRPIMHLALSYDSRFVRGKEAAAFLAYLKGILECPAVMLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHL4</accession>
    <name>A0A0C1HHL4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rplQ</name>
        <name evidence="6" type="ORF">DB41_EI00190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383828.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76804">
        <property type="protein sequence ID" value="KIC76804"/>
        <property type="gene ID" value="DB41_EI00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.502"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="142" mass="16389" checksum="4DAACD6ED656F595" modified="2015-04-01" version="1">MRHRKDTCKLSRTSSHRRCMFANMLKSLIENERIETTVPKAKALRRYADKMITLAKKNTLATRRRAISEMMVRFNALTDKEARAARKGDTSAYNTDRQVIDKLFSVLGPRFASRAGGYTRIVKAQRRVGDNTQMCIIEYLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHX4</accession>
    <name>A0A0C1HHX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_DS00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383620.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76929">
        <property type="protein sequence ID" value="KIC76929"/>
        <property type="gene ID" value="DB41_DS00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.383"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="388" mass="43928" checksum="DC3D2F67EFB5B7B7" modified="2015-04-01" version="1">MKANRIPAHQLEEIMPILLGAWRRMHKEAGPADKLQTREFRRVVEGVKNLQVGLETGHQLIGRDYFTDKDLLGSYLLYHWVVNYQQGLSILGEIPFKPKRVLDICSGPGAFSLAAIKHGASEVTALDYNQAALQLGAEVCGRSGYALSIRSWNCLTTPLPLEGKFDLIIVAHCLKELFPINSAHWQTKQNEFLSMLLNRLTPAGYLVVVDSSHPEANQRILQIRDCMVRKKVPIQAPCVWKGECPALQAKNNPCYAQREFYKPYIIKEIQRAAQINLGSLKMSYIIFRNPQAEWPILEEKKYYRVISPPVESFHGTRFYLCGVDGKKHLGSRLQVLPSESKAFEYLRRGELISIEKAHENQNAMDIIENTHVKVAAACGKPIPEIINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIE8</accession>
    <name>A0A0C1HIE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">mRNA interferase YafQ</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yafQ_2</name>
        <name evidence="2" type="ORF">DB41_DK00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000027">
        <property type="protein sequence ID" value="KIC77039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77039">
        <property type="protein sequence ID" value="KIC77039"/>
        <property type="gene ID" value="DB41_DK00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="42" mass="5164" checksum="7E4B0F0AD9570512" modified="2015-04-01" version="1" fragment="single">RLVGNFKGRWECHIEPDWLLVYLKTDQEIIFERTETHSDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIF5</accession>
    <name>A0A0C1HIF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-ribose pyrophosphatase</fullName>
            <ecNumber evidence="2">3.6.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nudF</name>
        <name evidence="2" type="ORF">DB41_DI00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.13" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000025">
        <property type="protein sequence ID" value="KIC77044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77044">
        <property type="protein sequence ID" value="KIC77044"/>
        <property type="gene ID" value="DB41_DI00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="170" mass="18966" checksum="EA722C2C901FC89E" modified="2015-04-01" version="1">MTLLDFSKILFLINSYCLSSKSLVGEDRSDNMNQIIRHGAYGVIFQDSKILLTQKKSGPYEGLWGLPGGAIEFGETPEATLKRELLEESSIAISKVEFLSIATSTGNYDNNGVSYGFHQVGLLYKILGWEKQPGLVPQEENRWVRLTDILQKELTPFALHAISNLPTSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIL8</accession>
    <name>A0A0C1HIL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Insertion sequence IS5376 putative ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DB00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77094">
        <property type="protein sequence ID" value="KIC77094"/>
        <property type="gene ID" value="DB41_DB00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.191"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="153" mass="16921" checksum="45065996079359F3" modified="2015-04-01" version="1" fragment="single">GPPGVGKTHLAIALGREAILKGYSTLFISATALLTRLSNAHKKGQLEEELCQVSKPKLLIVDELGYLPFETDAAHLFFQLVSRRYEKGSMLITSNRSVGEWGTVFGDGVVATAILDRLLHHSQVITIRGESYRLREKMRSGLVKRGESTNEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIN0</accession>
    <name>A0A0C1HIN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74418">
        <property type="protein sequence ID" value="KIC74418"/>
        <property type="gene ID" value="DB41_IP00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4752" checksum="54F787B1158A6771" modified="2015-04-01" version="1">MTSCAILFIAKDVAYNTLSDNFLCSHILNKKLAFTMRASLVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIN2</accession>
    <name>A0A0C1HIN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DB00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77104">
        <property type="protein sequence ID" value="KIC77104"/>
        <property type="gene ID" value="DB41_DB00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="53" mass="6253" checksum="A3781F2583E75357" modified="2015-04-01" version="1">MPKRKATDKNFADLQEEIDLERFRESVRSNFADFPDPRLSKQGVYQIILIKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIR2</accession>
    <name>A0A0C1HIR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CX00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77144">
        <property type="protein sequence ID" value="KIC77144"/>
        <property type="gene ID" value="DB41_CX00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6219" checksum="2E188748737BE4E4" modified="2015-04-01" version="1">MAIGKLTGVPTKLLLIKDCQHFCLRSKELNNQLKNCFKLIFCYTNEPKACPYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK63</accession>
    <name>A0A0C1HK63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74893">
        <property type="protein sequence ID" value="KIC74893"/>
        <property type="gene ID" value="DB41_IB00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="241" mass="27955" checksum="5E9C8AF0F68129B1" modified="2015-04-01" version="1">MIRLIMFINDSIISGNYNPPLVKGQEVKNTKISFELSRLLEKIEWCRSKRFVELADENAKKNLDYILAAVVDENNQTTFYDGCQFTRFIQEVDGIYSPSTQAKIKDIYYYFLNPNKQELQPLFTKKDLESPLYWNYLFANDSLLEESARAECLFQLGNCYYQGSGVEVNMKYALEYYRRAINLANHAKAVLMLAYCYENGEGIEKNGESARYWYSQAAFHSSDPVVKQLASQKLACFEKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK68</accession>
    <name>A0A0C1HK68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inner membrane protein YbaL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ybaL</name>
        <name evidence="6" type="ORF">DB41_IB00310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74898">
        <property type="protein sequence ID" value="KIC74898"/>
        <property type="gene ID" value="DB41_IB00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1464"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="28"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="422" mass="45816" checksum="7AE9DBDA08CEBEE1" modified="2015-04-01" version="1">MFLRVFNLKEIGEDMSEELKIIWILAIGFGLACLLGYSAHRMKLSPILGYVIAGYLIGPNFPGFVADPRLSEQLANIGVTLLMFAVGLNFKWNDLAAVKKIVLPGALILSVLSIGAGIFLSVYLGQTMQAGFVIGLAICVSSTVVIVRGLVDQNLLQTPQGHTVLGWTIVEDIISVLGLILLPTLVHSNLGGENSGVEFMYSLGTLILKIIALGVIIYYVGEKLVKEVLTVVARTRSHELFTLAILSCVFFIAIGSAYLFGVSLALGAFIAGTVVGKTEVSHQAAANALPMRDAFAVIFFLSVGMLFNPTVVKNNLPLFFGLLFIILALRPMMAFLIIKLAKYPQSIAISVAVAISQIGEYSFILAEEGNQLKILSDNAYDILVACAFISIMLNPLLFQLFRPLASKKQKNFFLKIRRLINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKK3</accession>
    <name>A0A0C1HKK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74993">
        <property type="protein sequence ID" value="KIC74993"/>
        <property type="gene ID" value="DB41_HY00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="6562" checksum="C3C51DCE81CFE508" modified="2015-04-01" version="1">MIKEGFTCEEVSKQEVHNWHKDLAKVGLAFKMVKRDLEIQQSTFVRSGNKKRRWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNK7</accession>
    <name>A0A0C1HNK7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385000.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75883">
        <property type="protein sequence ID" value="KIC75883"/>
        <property type="gene ID" value="DB41_GZ00470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="1">
        <location>
            <begin position="191"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="338" mass="39944" checksum="210434EE8A12048F" modified="2015-04-01" version="1">MIKKISLALLLILIMTGLAFFYLAPRKQFLHYPQNTIYRSQTVQIAVPSCPLQANSLIVESIFPEKSLSQWTKRQHAESYHLLENTAQLWKDNEFIDNFMIIATIPPRMHADNFFWEIIPYTKKNYHLFEQLLVLGKLTFDSPCLPKAERQSIKRKYQDYLPFFSKSYRPIPEDNFCPPVDVFCQPEIIAKQLLYEGKHTHLLYNHAPIGIGEEKLHFIIIPKAHRTNFMELTLEEYVEAQEISSKLILYYKQRGYPIVYIFHKSGKYAGQTVPHWHEHLIFVPHRTHEFIGKLMVLQKMLFPTSPLNEKKFKKLVDIYRLQAKEALNSLNERNYTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRI5</accession>
    <name>A0A0C1HRI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_ES00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000057">
        <property type="protein sequence ID" value="KIC76743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383930.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000057.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76743">
        <property type="protein sequence ID" value="KIC76743"/>
        <property type="gene ID" value="DB41_ES00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="177" mass="19885" checksum="0A92A625F07ECD25" modified="2015-04-01" version="1">MEGTSNDYSSSHLTNRALFNESQTSKPMDKIGAIFQTIKDMRGKDNSLATVQSPEVLIDRLSVKHKIWQIKTNLLPLILSQNSAHVSIKQATSGTNGCYFIKYNFENQKIEGVFKPINETEKTRAGIPESEQAVREYLGYMLSQYLTAHLIKNNIRINIQNFGVPPTSIASFDKISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRW7</accession>
    <name>A0A0C1HRW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76863">
        <property type="protein sequence ID" value="KIC76863"/>
        <property type="gene ID" value="DB41_EC00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="64" mass="7215" checksum="B17C8AEFE1E8A73C" modified="2015-04-01" version="1">MTKAELIKKIAVLESVNDQIYSELYEVDRLMRLVGFEGGLETVKLTAQEIYQSGHVGEEGEENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS83</accession>
    <name>A0A0C1HS83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DP00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000032">
        <property type="protein sequence ID" value="KIC76953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383553.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76953">
        <property type="protein sequence ID" value="KIC76953"/>
        <property type="gene ID" value="DB41_DP00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="173" mass="19900" checksum="F210326C14FC1232" modified="2015-04-01" version="1">MHSAYLLFLLLMHTVLPLKAGTIPIELEIAFTEEERAWGLMQRSHLPENRGMLFYFPKGNLWMFNTLIDLSAAFLDEKGSILEIAELKSYPEMMDPHRPVNKLSEMRKYPADDKIFLFFLQKSKALPTGTYYILEMNKEWFKKKGVTVGDKVVWHLNSSQASIVKLSSPSSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJD6</accession>
    <name>A0A0C1JJD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_BB00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000222">
        <property type="protein sequence ID" value="KIC71470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71470">
        <property type="protein sequence ID" value="KIC71470"/>
        <property type="gene ID" value="DB41_BB00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="DDE_3" evidence="2">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="76" mass="8454" checksum="4F24024394A6BDF7" modified="2015-04-01" version="1">MIPELKTGQVLIMDNATFYKSQATHELIKKAGCEILFLPPYSPDLNPIETFWANFKKIVAANLSSTTSLGLRGIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKK4</accession>
    <name>A0A0C1JKK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthetic protein FliQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fliQ</name>
        <name evidence="8" type="ORF">DB41_AF00110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386690.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000206.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71825">
        <property type="protein sequence ID" value="KIC71825"/>
        <property type="gene ID" value="DB41_AF00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2153"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006306">
        <property type="entry name" value="T3SS_HrpO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01403">
        <property type="entry name" value="fliQ_rel_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC71825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10184" checksum="B3CC854E16A843B5" modified="2015-04-01" version="1">MFQTQVIQLAYHALLLILILSAPPILVSMFFGVIVAIFQAATQIQEQTLSFTIKLVAVTLTLMLLGGWLGAQIMEFAGDIFSHFAQWSLASQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLU1</accession>
    <name>A0A0C1JLU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KQ00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386474.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72240">
        <property type="protein sequence ID" value="KIC72240"/>
        <property type="gene ID" value="DB41_KQ00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="124" mass="14578" checksum="64C2C02CEFC7E266" modified="2015-04-01" version="1">MEGLKDRRPKITGRKRALTFKQEKAFLERVEKGTKSEENINVFHLRDLQAILKKEFSKNLTVPGIWAILRRCHYATLGPPALKHYKANLREQEALKKIPEVITTLNKQFLKQKIEVWLEDEARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLX4</accession>
    <name>A0A0C1JLX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KP00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000195">
        <property type="protein sequence ID" value="KIC72275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72275">
        <property type="protein sequence ID" value="KIC72275"/>
        <property type="gene ID" value="DB41_KP00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5511" checksum="4039E0AD38826E5B" modified="2015-04-01" version="1">MILKSYKKACYWVLNFLLLLERFCRVYYSLLNLARGKAKALRIKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JM27</accession>
    <name>A0A0C1JM27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tyrosine-specific transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tyrP_4</name>
        <name evidence="9" type="ORF">DB41_AV00310</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386935.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71591">
        <property type="protein sequence ID" value="KIC71591"/>
        <property type="gene ID" value="DB41_AV00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2269"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC71591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="405" mass="44139" checksum="0351DFBA811CF04B" modified="2015-04-01" version="1">MDNQTFASQGSILGAILLVAGCCIGAGMLGLPVLSAQAGFKPSVIMFIICWIFMLSTGLLLLEANLWFKEDINVVSLADRTLGKMGKAVGWIVFLFLFYSLMVAYVAGSGALFADFFDLFFAIHLPRWVGGLIMSALFGLMIYSGTSTVDKFNRLLMFGLLLTYLLIVCIGSSHIDQKLLKHYDWPAAFFVIPAMIVSFGFHNLVPSLTQYLGRDSRRLCIALAMGSFIPLIIYLAWQRLILGIVPLEGEDSLRVACSEGQMATQALKIVVGASWVVDIAQFFAFFAIVTSFLGVSLSFVDFLADGFKIPKRSGGKIALCSLALLPPYLFSLIHPGVFLTALNYAGGFGAVIIFGILPALMVWSGRYHKNFKGPQFIAGGKPILLLIILCSVSIIILQLYQTITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMK0</accession>
    <name>A0A0C1JMK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_KK00260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386402.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72500">
        <property type="protein sequence ID" value="KIC72500"/>
        <property type="gene ID" value="DB41_KK00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="282" mass="33390" checksum="9C895239919D73DE" modified="2015-04-01" version="1">MRRFLIFFGWLLILQTLNAGYKYELSSCAIFMEDDLPYMPEWIEFHKHQGVQHFYLYNNGPVNVWKPYLDQYEREGFIEVIEWNYGSQNVIEWNSIQTQAYMHCLKKITKESKWCAIIDTDEFLFTLPYKNLRKALRNYEEFAGVVANWVMYGTSNVDYIPEGQKLTDLLVRRGAVDGDLHVKSIVKPAYVVDIMNPHSFIYSTNKFAVNENKELVLGAFTAKNSVNIFRINHYWCRDKSFLINTKLARRLKWGQPIESVLEIEKGYNLEHDDLIKNFNNYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMK3</accession>
    <name>A0A0C1JMK3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sufS</name>
        <name evidence="6" type="ORF">DB41_AI00030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000207">
        <property type="protein sequence ID" value="KIC71796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386716.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000207.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71796">
        <property type="protein sequence ID" value="KIC71796"/>
        <property type="gene ID" value="DB41_AI00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2158"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="5">
        <location>
            <begin position="28"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC71796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="412" mass="45901" checksum="252BB19D4E102808" modified="2015-04-01" version="1">MKPASFDVEKIRKDFPMLAKTMHGKPLIYFDSSATAQKPQCMIDSIQDFYQNHYSTVHRTIYESSLLATKKYQGAREKVQKLLNASKSEEIIFTRGTTDSINLVAYSFGKAFIKPGDEIILTQIEHHANIVPWQMMCEDRKAVLRFIPLDSQGNLKLEEFAKLLNSKTRLVALTHVSNAIGTINPVHEMIQMAHAYGSKVLVDGAQAVPHMKVDVQALNADFYAFSGHKLYGPTGIGILYGKAELLNQMPPYQGGGDMIDKVDWEETTYNVLPLKFEAGTPLIAEVIGLGTAIDYINTIGFSAIHAHEQELLEYAIKKMESIPQVRIIGKPKEKAAIISFIVEGAHPLDIGTMLDLKGVAIRTGHHCAQPTMRHFGVPATARISFGLYNTKEEIDHFIIYLQEVIELLCASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JMM8</accession>
    <name>A0A0C1JMM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Nodulation protein NolT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">nolT</name>
        <name evidence="12" type="ORF">DB41_AF00070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YscJ lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000206">
        <property type="protein sequence ID" value="KIC71821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71821">
        <property type="protein sequence ID" value="KIC71821"/>
        <property type="gene ID" value="DB41_AF00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2149"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003282">
        <property type="entry name" value="T3SS_HrcJ/YscJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01338">
        <property type="entry name" value="TYPE3OMKPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02544">
        <property type="entry name" value="III_secr_YscJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="11">
        <location>
            <begin position="32"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="299"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC71821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="330" mass="36672" checksum="254ECC5B43877930" modified="2015-04-01" version="1">MYNLITLASHQMLRFFAYSLLIASSFLFTSCESQKTIVNSLDEREANEILVFLESKGINANKMQSAGGGTGASKIVLWDVSVNEKDAIQAMALLNQAGLPRKRSQNLLSIFSNVGLVPSERQDKIRYEAGLAEQIASVIRKIDGVLDAEVQLSFPEEDPLSPGKTKGKITASVYVKHNGVLDDPNSHLITKIKRLVAASITGLNFNDVTVISDRARGSDLSTSFLSGEHEEKSYVSIWTIVLAKESVTRFRVVFFTFSFLLLLMAVCLIWLTWKIYPLLKRHGGFKELFHLQPLKIGAPEEEKTQDTEEPAEDKNSSEDKGLVDKDVDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPC4</accession>
    <name>A0A0C1JPC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KN00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000193">
        <property type="protein sequence ID" value="KIC72386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72386">
        <property type="protein sequence ID" value="KIC72386"/>
        <property type="gene ID" value="DB41_KN00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
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    </dbReference>
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        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1810"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1810" mass="201853" checksum="0098B7D2F164888C" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPU6</accession>
    <name>A0A0C1JPU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000190">
        <property type="protein sequence ID" value="KIC72541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72541">
        <property type="protein sequence ID" value="KIC72541"/>
        <property type="gene ID" value="DB41_KJ00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="5052" checksum="30DFABED499412E6" modified="2015-04-01" version="1" fragment="single">MTSLKIRWLKVFYFILAHPKLKSTYYSTIENAALFFRRYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JR14</accession>
    <name>A0A0C1JR14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JE00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000162">
        <property type="protein sequence ID" value="KIC73600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73600">
        <property type="protein sequence ID" value="KIC73600"/>
        <property type="gene ID" value="DB41_JE00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="6444" checksum="56C7FE6F65575829" modified="2015-04-01" version="1" fragment="single">YNLRNVGYRRNLPYSPFFSPFLSVAYMIFPLKLCKKTSLNQNILESIDKILSNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JRN0</accession>
    <name>A0A0C1JRN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JS00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000175">
        <property type="protein sequence ID" value="KIC73121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73121">
        <property type="protein sequence ID" value="KIC73121"/>
        <property type="gene ID" value="DB41_JS00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="7289" checksum="FEDE915DFC837994" modified="2015-04-01" version="1" fragment="single">QKHRFLKNYFQQMNWLKSGFFKSFIHLLYSLNLLNLAHELSVFLTCKKASKRLTSFSLYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JSQ9</accession>
    <name>A0A0C1JSQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IT00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000151">
        <property type="protein sequence ID" value="KIC74145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386063.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000151.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74145">
        <property type="protein sequence ID" value="KIC74145"/>
        <property type="gene ID" value="DB41_IT00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="635" mass="72853" checksum="4C30C84C603F61D8" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JU50</accession>
    <name>A0A0C1JU50_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4 8">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pncB</name>
        <name evidence="12" type="ORF">DB41_II00050</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4 8"/>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74620">
        <property type="protein sequence ID" value="KIC74620"/>
        <property type="gene ID" value="DB41_II00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1571"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041619">
        <property type="entry name" value="NAPRTase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006405">
        <property type="entry name" value="Nic_PRibTrfase_pncB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="PTHR11098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17956">
        <property type="entry name" value="NAPRTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01513">
        <property type="entry name" value="NAPRTase_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAPRTase_N" evidence="10">
        <location>
            <begin position="2"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase" evidence="9">
        <location>
            <begin position="65"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase_C" evidence="11">
        <location>
            <begin position="273"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC74620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="404" mass="45115" checksum="574FB4CC929306B3" modified="2015-04-01" version="1">MKFSCHLDAIPEGTIVFPYEPLLRIQGPLIQCQILESPLLNLINFPTLIATKAARVRVAAQSDQVLEFGLRRAQGFDGSLTASRAAYIGGCNATSNVLAGKLFGIPVKGTHSHSWVMVFDDELESFKTLAQSMPANSLFLVDTYDSVEGVKKAIQVGQWLKSQGKIFHGIRLDSGDLAYLSHTSRKMLDEAGFPQAVIVASNELDETQISELKYQKAPIGVWGVGTKLVTSHDCPALDGVYKLSALRDPEGPWKYKLKLSEQMIKISNPGILQVRRFRNTSSSPIADMIYDINMPVSPEPCLINLNDSTEQIVLKKELQSEELLVPIFRQGKCVYPLPNLEKIRERTLKELEKFPKNSKLLKHPCPYLVGMEKSLHAYKSQVVNHIRPQICQSSFFTKKGMKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUJ0</accession>
    <name>A0A0C1JUJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IF00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385886.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74760">
        <property type="protein sequence ID" value="KIC74760"/>
        <property type="gene ID" value="DB41_IF00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1557"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="197" mass="23311" checksum="0A4650583025F5A7" modified="2015-04-01" version="1">MKENLTNLQERPRCAWVPKDHQLYEAYHDNEWGVAVHDDLKHFEFLILESAQAGLSWETILKRRLHYAEAFANFNWIEIAKFNQQKVENLMKNSGIIKNRLKIQAAINNAQRFMEVREEFGTFDTYVWQFVGGKTKNNYRKSIKEVPSETEESRALSKDLRRRNFKFVGPTIMYAYMQAVGMVNDHTQDCFCYVQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JUX5</accession>
    <name>A0A0C1JUX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74870">
        <property type="protein sequence ID" value="KIC74870"/>
        <property type="gene ID" value="DB41_IB00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5385" checksum="45739FEA99A3AF2B" modified="2015-04-01" version="1">MIAYYFFASQQFANRDIKIIYFRAALYANIYLKKLLVRKESAFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV34</accession>
    <name>A0A0C1JV34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74930">
        <property type="protein sequence ID" value="KIC74930"/>
        <property type="gene ID" value="DB41_IB00630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7181" checksum="C962299DB87EA914" modified="2015-04-01" version="1">MLFSSFLEGQKKIFSLKLFIPFKCSRLGRESLNRSSLKSFTAKWLDPTTAYFIHQPLVKPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV84</accession>
    <name>A0A0C1JV84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative rRNA methylase YtqB</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ytqB</name>
        <name evidence="1" type="ORF">DB41_IB01030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385802.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74970">
        <property type="protein sequence ID" value="KIC74970"/>
        <property type="gene ID" value="DB41_IB01030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010719">
        <property type="entry name" value="rRNA_methylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35276">
        <property type="entry name" value="PTHR35276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06962">
        <property type="entry name" value="rRNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="201" mass="22597" checksum="AE190AB7C48A0EB0" modified="2015-04-01" version="1">MRAQFPLFNSHLELAHLYWEKLVHKGDLVIDATCGNGQDTLILAQLCADLKGGLIYALDILPRAIELTQKYLHEKLPSVHFQQVRFILGCHSTFPEEISPESVKLITYNLGYLPGGGDKTLTTTAKTTLESIKKAMLLLQPGGAISITLYPGHPEGQCEEQSVLSLVEKLNPLEWSCSHHQWINRHKKSPHLLFIQKRLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVC1</accession>
    <name>A0A0C1JVC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HY00360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243965.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75010">
        <property type="protein sequence ID" value="KIC75010"/>
        <property type="gene ID" value="DB41_HY00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="9053" checksum="4DB5AF300F9C35AB" modified="2015-04-01" version="1">MKFILYFIFFGLLFYVIALYFPEAFQTLVSWADKVFAFLQNLFIAAIDKANLMMSTPPAIPEQPVHFEAPQELACLWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWG1</accession>
    <name>A0A0C1JWG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aquaporin AQPAe.a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">DB41_IF00030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385882.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74756">
        <property type="protein sequence ID" value="KIC74756"/>
        <property type="gene ID" value="DB41_IF00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="PTHR19139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC74756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="225" mass="23022" checksum="BA13C870417397AE" modified="2015-04-01" version="1">MNIARLLAEFIGTFTLIFIGAGSICLNEMTHGGVGLLGIAVAHGLALAVMVSALAHISGGKFNPAVSLAVWAGGQQNTILTFTEIVAQLLGAIVGAFALKGIFPAATLSLAKLGTPMIESSLSSSVGIFIEAILTFLLVLVVYGTVVDTRGDSKGIGGFAIGGFILCGILMGGGITGAAMNPARAFGPALVAGEWAYQYVYWIGPIIGGLLAGILYSRLLMKHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWU0</accession>
    <name>A0A0C1JWU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AQ00030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000213">
        <property type="protein sequence ID" value="KIC71712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244116.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000213.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71712">
        <property type="protein sequence ID" value="KIC71712"/>
        <property type="gene ID" value="DB41_AQ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="33"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="749" mass="86447" checksum="EE2EC24585FEC7CA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX36</accession>
    <name>A0A0C1JX36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HY00170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243959.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74991">
        <property type="protein sequence ID" value="KIC74991"/>
        <property type="gene ID" value="DB41_HY00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="364"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="486" mass="54704" checksum="A1296C14A0C4A173" modified="2015-04-01" version="1">MQVQNLSPAPLSKTSPATPVSAISPDVHKMLQNPELYAMVEGTLCGRLVKLLLARCNTTLEKHLYAYKAKGVVLSESLQIILGIAQATDNQEALDILYKYNPNLASICHIKLMAHRFSIVGKSQINGQFFELEGSDHRITFQALYNSLKQHLDLPEQEIILPIIEMILKVEKDPTIMPEILLDAYHQGKTIFLPLVFKLITASHIYGFLIKGNRLIKLNKGLHADLPTGLHIYKIADPSKINIEYIHRLLNTNVLRTYFEKGVDKELGLVHDHYIPTTLQKAGVCSWSIAKLALRGGFILEGIENGKIKYKKWSQADRFATVIDYLKQENVDPHLIASLWCRTKDQKIKEALEDRLTTTHIANENSTSLHLAAESNNFSVVEKLLMEGENINSEDAEGWTPLIAAACQGHVEMVEYLLERGAYVNKTGKTGLNAYWHLLSQQGECSKNPKMENHIKKVKQLLIEKGIDTDLSNGFRLMAQRHAKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXF7</accession>
    <name>A0A0C1JXF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HG00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75755">
        <property type="protein sequence ID" value="KIC75755"/>
        <property type="gene ID" value="DB41_HG00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6395" checksum="E8E941994315349C" modified="2015-04-01" version="1">MVRISKQAERRSKSHRKPSPPAKKTGPRKENLKEGFKSHSNALEGAIAKQAFIPKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYS2</accession>
    <name>A0A0C1JYS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GM00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000098">
        <property type="protein sequence ID" value="KIC76125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243895.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000098.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76125">
        <property type="protein sequence ID" value="KIC76125"/>
        <property type="gene ID" value="DB41_GM00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="881" mass="100616" checksum="A5509DD79D1E4FE7" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ39</accession>
    <name>A0A0C1JZ39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Salicylate biosynthesis isochorismate synthase</fullName>
            <ecNumber evidence="2">5.4.4.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pchA</name>
        <name evidence="2" type="ORF">DB41_GL00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.4.2" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76275">
        <property type="protein sequence ID" value="KIC76275"/>
        <property type="gene ID" value="DB41_GL00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.950"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008909">
        <property type="term" value="F:isochorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="23"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="240" mass="27115" checksum="43A41514B5A0DD56" modified="2015-04-01" version="1">MPYIFEESLSTMTPDRLGSSLKHLINYVKDQQLHVYGYWEETEGILGASPEILFNYHNASEGLIETVACAGTKRYRDSDSIFIQDSKELYEHQLVIEGIQESLSSLGVVTIGELQILQLPKISHLMTPIQLKMKGPSNFLALVKALHPTPALGAFPKEEGRKWLHLYNDKIDRWRYGAPVGCLFDNKRQARCIVGIRNVQWNSQGAKIGAGCGIVPASQWHHEWQEINLKLLSTKEMIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZA1</accession>
    <name>A0A0C1JZA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Polynucleotide phosphorylase</fullName>
            <shortName evidence="6">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">pnp</name>
        <name evidence="8" type="ORF">DB41_HF00050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385129.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000116.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75776">
        <property type="protein sequence ID" value="KIC75776"/>
        <property type="gene ID" value="DB41_HF00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1161"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="623"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="696" mass="76568" checksum="EF948A30D42AA524" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZF4</accession>
    <name>A0A0C1JZF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein in dhlA 3'region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75851">
        <property type="protein sequence ID" value="KIC75851"/>
        <property type="gene ID" value="DB41_GZ00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="15572" checksum="32EA15B659029045" modified="2015-04-01" version="1">MIAQEKLQEKASETPAVPALLEAMDVSGAIVSMDALYAHIDTINEVLNKGADYIVGIKGNQGHLKAEAYNFFEQAKAVNYQGVEGITREETHEKNRGRIESRHVCVVNALQWLPQREKWHLQSMIEVRSERKVADKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZH5</accession>
    <name>A0A0C1JZH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GF00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76410">
        <property type="protein sequence ID" value="KIC76410"/>
        <property type="gene ID" value="DB41_GF00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6533" checksum="1867184F273FE7E7" modified="2015-04-01" version="1" fragment="single">MIFIIYVDIYLKAAIWCNIFDLKKWLEESKEKLKAGKSRKVFKEIEIKFKALDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZJ0</accession>
    <name>A0A0C1JZJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GE00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000090">
        <property type="protein sequence ID" value="KIC76420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384582.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000090.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76420">
        <property type="protein sequence ID" value="KIC76420"/>
        <property type="gene ID" value="DB41_GE00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="30111" checksum="4C6C4D677BC08BEB" modified="2015-04-01" version="1">MRSFTLTMQYFIGEGKKRNPLLFYLAILNFALAIFLLSLIPLGSTVASETIPWIKPIKFAFSFGLYLLTIGWILVYLKISTKMFLAISRLTALLIFMEMLVIVLQSIQGKIYHFSIEQPLTLAICYGMCLYLFSHLLIVANTLIASYILYLFFQPTTLCSPAYLWGIRLGLVIFLLSCLEGGFIAFQDMYWRQGQVLSGWGLPFADYTSRGYLTSSHFFGLHALQALPVIGYTLRNRLHSQQLLFSIGIIYFTIFVYLFGKAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZV1</accession>
    <name>A0A0C1JZV1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1 3">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ndk1</name>
        <name evidence="1" type="synonym">ndk</name>
        <name evidence="5" type="ORF">DB41_KC00020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1 3"/>
    <dbReference type="EMBL" id="JRXI01000184">
        <property type="protein sequence ID" value="KIC72812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72812">
        <property type="protein sequence ID" value="KIC72812"/>
        <property type="gene ID" value="DB41_KC00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1851"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="4">
        <location>
            <begin position="73"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC72812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="213" mass="23537" checksum="39A3620BB7FB187F" modified="2015-04-01" version="1">MQILHTLSMKIAYMVQILLKMLKPKLAISLKALKSALIPVKTIRIFTMLRTTLVFLFACLTPFSLMAAGDPSPQQTLSMIKPDGIANRHVGEIIARFEKNGLQISAAKMLHLTAEQAGQFYAVHKDRPFYKDLINMMSSGPVMVMVLEGEDAIAKNRQLMGATDPSKAAASTIRADFSRSVTENTVHGSDSVENAKLEIAFFFKPEEIVNPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZW7</accession>
    <name>A0A0C1JZW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 15" type="primary">leuS</name>
        <name evidence="15" type="ORF">DB41_GR00080</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="JRXI01000103">
        <property type="protein sequence ID" value="KIC75996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75996">
        <property type="protein sequence ID" value="KIC75996"/>
        <property type="gene ID" value="DB41_GR00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1004"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="13">
        <location>
            <begin position="46"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="14">
        <location>
            <begin position="228"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="622"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="700"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="624"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC75996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="846" mass="97458" checksum="50EA75F95BA63579" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0B5</accession>
    <name>A0A0C1K0B5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384162.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76605">
        <property type="protein sequence ID" value="KIC76605"/>
        <property type="gene ID" value="DB41_FI00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="80" mass="9280" checksum="D15D47E10D0CFE55" modified="2015-04-01" version="1">MYRLAFLMGIVVIGYMPLEAGEEQNVGEQESQIKEDCYDPKTQARLLYGRAIDSPIGDLNEKNYEWPGMRADSFYDYFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0C6</accession>
    <name>A0A0C1K0C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FI00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384183.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76615">
        <property type="protein sequence ID" value="KIC76615"/>
        <property type="gene ID" value="DB41_FI00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="134" mass="14552" checksum="6DB7A76ED1F866FE" modified="2015-04-01" version="1">MTTLVSVDLKSDRGSIHLPVNPAWREKASQTFSKVKEVANVVFISLLTIALFATNPGMCFISLVIGIAFSKSIEKAVNRIKVFLSAYSVPVIIGCWGIGMLVLPVFLATAAVIWQASLGSYLSKKADEKMLYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0I1</accession>
    <name>A0A0C1K0I1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative membrane-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FB00170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76675">
        <property type="protein sequence ID" value="KIC76675"/>
        <property type="gene ID" value="DB41_FB00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="150"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="417" mass="47838" checksum="D90F21EA8B4B6FC8" modified="2015-04-01" version="1">MKKKYLLGPFAFYALPVSIMLIWWSLAFKQPNDQASDPCPLCPSAQPLPSIFKYLSTLQRETLHQALNGDYSMMSKLITDWDHDAQIMEQYGYRTAKRLLRDDFLRCQLLARQINNSSKEELDLLHDYYRLSSIQDDNGNIFDLSTSYKRFLPQTFVAASFLLALSEPELIVALPTGMRKQTSIYPVQATHLIALDADRYNTEKLYNARPDIAFVADYSNPSTLEALNKQGIPLFTLKHVNSPEEVQNALLRIGHIINRPIEAELLNYFVEAAMLAIDNRFNMISSTFPSTQQPPKVLFLKHHLTFSTPSSHTLTGKLLNRMGVKQLLGTAGNPSKHAWTLPIHHEHIRQMDPDYIIIATSDKDDNKRRFLKKQIFQLLKEKPNKPIAFVNEALQENPSQYMVLAYYDLYTALTRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0V4</accession>
    <name>A0A0C1K0V4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GG00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000092">
        <property type="protein sequence ID" value="KIC76396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384603.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76396">
        <property type="protein sequence ID" value="KIC76396"/>
        <property type="gene ID" value="DB41_GG00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="85" mass="9690" checksum="9271185DA058D9F3" modified="2015-04-01" version="1">MKNIRSISATQARKHLGKILVEVNYHKQRILLTNHKKPVAIVPIEDLETLEAREVAQDIHEAKKALKEIEAKGTISLKEMKKRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Z8</accession>
    <name>A0A0C1K0Z8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GC00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76456">
        <property type="protein sequence ID" value="KIC76456"/>
        <property type="gene ID" value="DB41_GC00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="195" mass="22152" checksum="5142AF29E3E8192F" modified="2015-04-01" version="1">MYGYGKNIVDDMFLASKNSYKENSSVSEPVLEGWIDYIPASKSFTSKFPAIPQHATDRALDSKTKESKQYEMYVSENNDHVFMISVISFLDVNKIRDSEKALKNIVDDMVVSNPGNRLEKFQQGSLEDIKNVEFLITNESYTIKGRAFLAKNKLYVLSVLSKSAADPSLEFEYFFKSFKINKDSSPSLLSFSTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K188</accession>
    <name>A0A0C1K188_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DZ00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383709.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76885">
        <property type="protein sequence ID" value="KIC76885"/>
        <property type="gene ID" value="DB41_DZ00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="150" mass="17898" checksum="300F226362A33219" modified="2015-04-01" version="1">MGCFFFNFNPFNCIDLRPWRLITESPPSIKTIPEELIVHIFSFLSPKELGKAQQVCKHWKRIGNEETLWKRHHQQQFKDKPLHISFYPKVLRSFRNSYLVYSRFELIDRKVKLEIASVCAHPDYNGRSFSELLLLMNQSQSFNHQKSLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1B7</accession>
    <name>A0A0C1K1B7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FR00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000079">
        <property type="protein sequence ID" value="KIC76536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76536">
        <property type="protein sequence ID" value="KIC76536"/>
        <property type="gene ID" value="DB41_FR00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5716" checksum="89386A6700A77D26" modified="2015-04-01" version="1">MLTQKAEKLKSLVDEDENLLKIKSFRAGGTFRDRVLQQLKEKISFFSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K241</accession>
    <name>A0A0C1K241_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_ET00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383943.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76736">
        <property type="protein sequence ID" value="KIC76736"/>
        <property type="gene ID" value="DB41_ET00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.558"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="617" mass="71465" checksum="80561F9604BF3680" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2A8</accession>
    <name>A0A0C1K2A8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">TPR_MalT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DB41_EI00210</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76806">
        <property type="protein sequence ID" value="KIC76806"/>
        <property type="gene ID" value="DB41_EI00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="313"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="12">
        <location>
            <begin position="321"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="397"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="439"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="481"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="523"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="565"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="607"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="755" mass="85728" checksum="DD1DBE226FDEF0BF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2B2</accession>
    <name>A0A0C1K2B2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383842.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76811">
        <property type="protein sequence ID" value="KIC76811"/>
        <property type="gene ID" value="DB41_EI00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="82" mass="8614" checksum="14CD8A6713CB9DF2" modified="2015-04-01" version="1">MAAIKKPAANKTTAKKTAEKKPAAKKPVAKTAVAKKTLTVKKTAPKIVAKATVKKPVAKKPIVKKAVVKKTTTAARKKAVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2J7</accession>
    <name>A0A0C1K2J7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DW00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76901">
        <property type="protein sequence ID" value="KIC76901"/>
        <property type="gene ID" value="DB41_DW00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5757" checksum="5C438A1A20C13177" modified="2015-04-01" version="1">MHLISQNFLDLFVWLKYNIFLLLFFEKAVELYLLEFLKIPPLKWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2J8</accession>
    <name>A0A0C1K2J8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CO00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77235">
        <property type="protein sequence ID" value="KIC77235"/>
        <property type="gene ID" value="DB41_CO00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4529" checksum="CD991A223EEB3C37" modified="2015-04-01" version="1">MFVACYHTIEKLNALAKKKECASYSAKLRAVAMAMEGESAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2Q9</accession>
    <name>A0A0C1K2Q9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Toxin-antitoxin system, antitoxin component, Xre family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JD00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000161">
        <property type="protein sequence ID" value="KIC73612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386116.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000161.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73612">
        <property type="protein sequence ID" value="KIC73612"/>
        <property type="gene ID" value="DB41_JD00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1725"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="98" mass="11336" checksum="B8DF159B438E239E" modified="2015-04-01" version="1">MRKKTVRKNKHLGSDFDDFLREEGILEECEEVAAKYAFVMQLEDEIKKQNLTKEEFAKRMKTSRSALNRLLDPTRPSNLTSFVNAALAIGRHVRVNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K306</accession>
    <name>A0A0C1K306_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JA00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000158">
        <property type="protein sequence ID" value="KIC73717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386103.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000158.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73717">
        <property type="protein sequence ID" value="KIC73717"/>
        <property type="gene ID" value="DB41_JA00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="174" mass="20246" checksum="B54F8B3A6CA9DB6E" modified="2015-04-01" version="1">MNTSSSITLEHLPNEILAPILKVCVTPSLFSVCTRWRHLLATEVMPSLYKQIGKMHAPHRDVNEQTLILDRIYKLEEDLSVTTKVNAIFKQTFTLASSLSPMELEFKCKAEEKRCFTLSNYTSYLVNINRLLMWKNLPSGREYLEQEKIKYLPLTKKGELFREWIENHGKVLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K338</accession>
    <name>A0A0C1K338_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="3">2.7.8.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pssA</name>
        <name evidence="3" type="ORF">DB41_DB00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383362.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77111">
        <property type="protein sequence ID" value="KIC77111"/>
        <property type="gene ID" value="DB41_DB00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.209"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="283" mass="31243" checksum="7212E1970EE155B1" modified="2015-04-01" version="1">MKKVYLLPNVITAFGLTCGLFVIFKISMITRGEVSAQALTEAAAILLLAAFADLLDGAVARAMKAQSEFGGLFDSLADAITFGVCPSVIILKSLALSPGTELSFFLTTGAMIYTVCGVLRLVRFSVHNRPSPILNVDFPLEEKPKNFTGLPIPAAAAAAVSGNLFLISEEFHHFISIQEITRAWILFFMMITIGYFMVSRWKFPSLKNLHIRVATFQVVFFTVVAAVFIIYGLLTHFSLVFFALSWIYLIVAWVLSLARIIAGKKAKALEDYEPEPEEDEDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K345</accession>
    <name>A0A0C1K345_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_CZ00070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383324.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77126">
        <property type="protein sequence ID" value="KIC77126"/>
        <property type="gene ID" value="DB41_CZ00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.181"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC77126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="139" mass="15340" checksum="A57EFB6EB6387554" modified="2015-04-01" version="1">MNLHTCHTVEQTINQGYDLGSQLPNGSIVCLFGELGAGKTTFVKGLAAGAAGITPQQVNSPTFVYLNIYKGHRTVYHFDLYRLRDADEFLSMGFEDMLFAGGICCIEWSEKIAPLLPPSCLKITLLHESESTRIIRIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K359</accession>
    <name>A0A0C1K359_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CW00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77156">
        <property type="protein sequence ID" value="KIC77156"/>
        <property type="gene ID" value="DB41_CW00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="57" mass="6808" checksum="73D261251F460C80" modified="2015-04-01" version="1">MFKIVVAKSFLFHFSPHPHLKSTYDHSTIENTALFFLQYLSEDFPLKRKIEYARCLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K373</accession>
    <name>A0A0C1K373_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Na(+)-translocating NADH-quinone reductase subunit B</fullName>
            <shortName evidence="14">Na(+)-NQR subunit B</shortName>
            <shortName evidence="14">Na(+)-translocating NQR subunit B</shortName>
            <ecNumber evidence="14">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">NQR complex subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NQR-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">nqrB</name>
        <name evidence="15" type="ORF">DB41_CT00030</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="14"/>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383224.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77186">
        <property type="protein sequence ID" value="KIC77186"/>
        <property type="gene ID" value="DB41_CT00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.118"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00426">
        <property type="entry name" value="NqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010966">
        <property type="entry name" value="NqrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01937">
        <property type="entry name" value="nqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 14" id="KW-0288">FMN</keyword>
    <keyword evidence="11 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="14" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 14" id="KW-0813">Transport</keyword>
    <keyword evidence="12 14" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="14">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KIC77186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="511" mass="56675" checksum="1BAB4E087668A8EC" modified="2015-04-01" version="1">MLRRLLSSLQKLAEPGKPLHKLHPLINANDTFLYEAAVNTRRAPHIRDAIDVKRWMILVVIALLPCIMMAIWNTGLLKYVYSSGDYKLMNEYLEASKNFQAYWAFATYDSRYIPIIMEGLKIFLPLTLLSYAVGGFWEAFFACVRKHEISEGFLVTGILYVLILPPTIPYWMAAVGVSAGVVLGKEIFGGSGMNIVNPALACRAFLFFTFPGKMSGDVWVGSNPTIIRESLLKMNQEGQTTAFDGYSQATKLAIFNVPQDIKRIHIDTIATHTIGTDVSTIQTIRTQFDQWNSLTHQNATLGQLTMDQIKSFVTSPLAEGGLGLSSGYYEDAYHFSSLNYGLGNNHDWSFFLGNKLGCLGETSTLACLLGALFLIWTGIGSWRTMLGMLLGAFGTALLFQLSSSYLFPNQGAWTAAQFGFPAYKHLLLGGLAFGLVFMATDPVSSPSIPLAKWIYGIFCGMVTLVIRVINPAYPEGVMLAILIGNVFAPLFDYYAVKHFRKRSISRVRIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K3A9</accession>
    <name>A0A0C1K3A9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CO00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77256">
        <property type="protein sequence ID" value="KIC77256"/>
        <property type="gene ID" value="DB41_CO00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.59"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011910">
        <property type="entry name" value="RfaF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02195">
        <property type="entry name" value="heptsyl_trn_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="363" mass="41329" checksum="57A175E19FD4CF21" modified="2015-04-01" version="1">MPNQLRLKSMKTPYFPWPSKPPKNIIVRMPNWIGDAVMATPLLTDLRRQWKEAKITVICQTPIDSVLQHHPDINSIYAFRRPKSWLNKFHHFEVIDFLQKGQYDLGLLLTNSFSSAWWFLKGKVQHRLGFADGFRSLLLNKAIPFPKNKEFQHQVITYKTLLGPLAIPVSSTPPQLYVSTQELQEAHHFLHRCGIDLQKNILVGINPGAAYGSAKCWPPERFNKLTKKLLENPNVFVIYFGDSNGVSVVNQICQDLPNRAINLAGRTSIRELIALLKCCSIFLTNDSGPMHIAAALGVRLLALFGSTNEIKTGPYPQGVVIHKHVECSPCYKRVCPIDFRCMTKIKVEEVYEQLERLLKENSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K540</accession>
    <name>A0A0C1K540_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74412">
        <property type="protein sequence ID" value="KIC74412"/>
        <property type="gene ID" value="DB41_IP00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="61" mass="7169" checksum="9C999DAD802FF467" modified="2015-04-01" version="1">MELFKILRVQYKTFFFIAKFLQVNKPTADNFIDAHGIFAKEFGIMVFNNSFGLRVKKTLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K543</accession>
    <name>A0A0C1K543_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IP00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000147">
        <property type="protein sequence ID" value="KIC74417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74417">
        <property type="protein sequence ID" value="KIC74417"/>
        <property type="gene ID" value="DB41_IP00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6642" checksum="7122036D574185ED" modified="2015-04-01" version="1">MIPNLPKSTKAAYGDSAYDKRAFYRSSYFQNIDPLVPPRREERFKAKRQTSCERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6J1</accession>
    <name>A0A0C1K6J1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">TPR_MalT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">DB41_IB00050</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385604.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74872">
        <property type="protein sequence ID" value="KIC74872"/>
        <property type="gene ID" value="DB41_IB00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="12">
        <location>
            <begin position="89"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="332"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC74872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="434" mass="49047" checksum="ED02BF1F644605DE" modified="2015-04-01" version="1">MLKFSNLEDDSPQTQGDIAARLFQYKEAKGFYSQALQENPENVRVLNALGMICCDQGELDEAIKCVESARAIDEKCPNTPYLNIVRDYSNLGTIAYSQKDLENATLYFNQAIEKSTDKNHPTMAILYNNLGQIYQAQGNLGKAAECAKRAIHIAGKNYPTLATYYNNLGKIYLDQNKLNKATEYVNRALTLNQRIFSENHFRVGINYNTLALIYQEQGKLKEATKYFKRSLAIAINLFGGDHPSIATRYNNLATIYKNRGGEKLKKALTFANKACDINIKLFGKNHPNVAIDRSTLGTIYYAQEKLEQAAQCFNEALTIDIEKFGINHPNLAIRYNNLGVVYMHLKKFREAAIAAKKALDINRKMFPDENHPNVATCYNTLGMIHKAQGNLYQATEYIKKALAINIRIFADENHLNVATCYSNLGLIYLDQKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K6S3</accession>
    <name>A0A0C1K6S3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome bo(3) ubiquinol oxidase subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cytochrome o ubiquinol oxidase subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Oxidase bo(3) subunit 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Ubiquinol oxidase polypeptide III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquinol oxidase subunit 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">cyoC</name>
        <name evidence="19" type="ORF">DB41_IB00700</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243977.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74937">
        <property type="protein sequence ID" value="KIC74937"/>
        <property type="gene ID" value="DB41_IB00700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1505"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02863">
        <property type="entry name" value="Ubiquinol_oxidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014206">
        <property type="entry name" value="Cyt_c_ubiqinol_oxidase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033946">
        <property type="entry name" value="Ubiquinol_oxase_su3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02842">
        <property type="entry name" value="CyoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="18">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KIC74937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="202" mass="22643" checksum="97229BCAE2C8E87A" modified="2015-04-01" version="1">MTDLTTLSSIHHADSSPATSAKTLFGFWIYLMTDCILFATFFATYAVLHNSTYGGPSAGQLFSPTFALIETLILLTSSFTSGLVMLAAHRQEKNRALSYLSLTFLLGLSFLTLEIMEFNYLIQEGNSWQKSAFLSAYFTLVSTHGLHILAGLLWVVVLGMQILSRGLSANTLRRLACFSMFWHFLDIIWIFIFTFVYLMGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K7I4</accession>
    <name>A0A0C1K7I4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_HW00340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385512.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000133.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75122">
        <property type="protein sequence ID" value="KIC75122"/>
        <property type="gene ID" value="DB41_HW00340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1390"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002134146" evidence="2">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC75122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="8163" checksum="FB2B73AA8BD41138" modified="2015-04-01" version="1">MKKFKKMIALTTLLAICGSTVDINAQEYVSNVGGICYEESRQAHSLAPAIALGTIAAVAIIAVAVQNRSHGHGHGHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K8I1</accession>
    <name>A0A0C1K8I1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4277 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HK00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000121">
        <property type="protein sequence ID" value="KIC75512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75512">
        <property type="protein sequence ID" value="KIC75512"/>
        <property type="gene ID" value="DB41_HK00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1256"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025457">
        <property type="entry name" value="DUF4277"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14104">
        <property type="entry name" value="DUF4277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4277" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5563" checksum="DD8943EAA689C1A6" modified="2015-04-01" version="1">MILNGLGFVSRTLYMYSEYFEDKPIDYLQRNLKIPAYKKVAKLKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9R3</accession>
    <name>A0A0C1K9R3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GY00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000110">
        <property type="protein sequence ID" value="KIC75902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384945.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000110.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75902">
        <property type="protein sequence ID" value="KIC75902"/>
        <property type="gene ID" value="DB41_GY00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008798">
        <property type="entry name" value="Avirulence_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036231">
        <property type="entry name" value="Avirulence_B/C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05394">
        <property type="entry name" value="AvrB_AvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103383">
        <property type="entry name" value="SSF103383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="405" mass="47526" checksum="7DE1F2CFC438F4E1" modified="2015-04-01" version="1">MNNIFPNYIIDREPMRYGGYQEDYQLKSKEIIHEGIRKIKISPQDNNSLTTLFFNLLEQFGTQRRKIAEAHETLEAAKFGLRRDTDGLNDWYHTILDGVYQDYNAKILKVLANHLQDMALETKSSQRHKKLTETCLNQNFSFEIKLLESEDYTALKWNRATSLEELKHYFNESQISLMKINEEDLSISEIRERRQAMKKLKESNIELYIRNKMVSFFSMMNKQFPSPKLVYQDGQQYYEGHTKNFKSFFLLGTARLQVNKKLFASTQYFTWLYRDAENRPVERMLKCSTVILIHQDNLLINETLQEIASIFAKAVLMPQENLNELKSTMALLRYYLAHAMPFERGSAAIGEWIEGAVYGSHGLKVTYQKEKQVDLEALTSPLFSQFLNEYSDMICLTDAHEDLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KAX0</accession>
    <name>A0A0C1KAX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GL00180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76277">
        <property type="protein sequence ID" value="KIC76277"/>
        <property type="gene ID" value="DB41_GL00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="220" mass="25371" checksum="6E1779BEEC85A01A" modified="2015-04-01" version="1">MALAKKKLRWHQVSQLTKRYTMRKYQLSLRRAAMTLLFFPLSVSIQTLSFTLPLTSLYQLHAASVQSFTDADLKQELRRLKQEPPIPSMPITRESSSSNDSKDPPAAFKYPSLTLEQTKQVNQEINIRVKEAEHFMQNQWRVVQDKTRMPMSIDKVQLENAITNLEVKKTLAAKFINSPSLKSPKVREILIQVLSKDLIQASDLAALQNIVDRERPYTYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KB89</accession>
    <name>A0A0C1KB89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GF00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76412">
        <property type="protein sequence ID" value="KIC76412"/>
        <property type="gene ID" value="DB41_GF00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6612" checksum="D2962EC1A14864F7" modified="2015-04-01" version="1">MIRPLARLITQKHASEIAKLKKETSSQEAIIISETDESMVPIATMDEIDKQVKKMQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KC45</accession>
    <name>A0A0C1KC45_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">galE</name>
        <name evidence="10" type="ORF">DB41_FB00090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384035.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76667">
        <property type="protein sequence ID" value="KIC76667"/>
        <property type="gene ID" value="DB41_FB00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.621"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="10"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC76667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="336" mass="37660" checksum="F6F66D29B0F1CBA8" modified="2015-04-01" version="1">MHKSNKKKVLVTGGAGFIGSTVNKLLHEAGYDTVILDNLSQGKRNRVKWGTFIEGDMSDSLLLKKLFANHQFDAVMHFAAFINVGESVHNPEKYYINNVSHTVNLLECIKEFSVKVFIFSSSAAVYGLPKTNFISEDHPTHPINPYGETKLIIEKILDDMDRAYGIKSAKLRYFNAAGGDPEGKIKNDFSASSNLIPIVLQAILDNRPVTIFGKDYPTPDGTCLRDYIHIYDLATAHIRAMEKLLAGGPTEIYNLGNGKGFSVQEVLQAAEKVTKQKIQVIEGPRRPGDPPCLLANAYKAKQELNWQIKYPSLEEMIYHAWTSLEKNKENNHFVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCP4</accession>
    <name>A0A0C1KCP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EF00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000045">
        <property type="protein sequence ID" value="KIC76847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76847">
        <property type="protein sequence ID" value="KIC76847"/>
        <property type="gene ID" value="DB41_EF00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="5220" checksum="899FD087B3F2ECE1" modified="2015-04-01" version="1" fragment="single">MFIKKTRSKNFVYLSLVKTFRENGKVKHRTIAQLGRLDRLLQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCU0</accession>
    <name>A0A0C1KCU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DZ00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383712.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76887">
        <property type="protein sequence ID" value="KIC76887"/>
        <property type="gene ID" value="DB41_DZ00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="143" mass="17077" checksum="80385AF9EA2DB16F" modified="2015-04-01" version="1">MGCFFFNFNPFNCINLHPWRLITEAPPSIKTIPEEVIVHIFSFLSPKELVNAQQVCKCWKKIGDEETLWKRHHQQHFKGKPLYISFYPRVLRSFRNSYLVYSRSESIRREVKLEIAALRASPSYNPIFSERLLWMNQSQSFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCV9</accession>
    <name>A0A0C1KCV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_DW00140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383692.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76902">
        <property type="protein sequence ID" value="KIC76902"/>
        <property type="gene ID" value="DB41_DW00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018821">
        <property type="entry name" value="DUF294_put_nucleoTrafse_sb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005105">
        <property type="entry name" value="GlnD_Uridyltrans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03445">
        <property type="entry name" value="DUF294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10335">
        <property type="entry name" value="DUF294_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="OTU" evidence="3">
        <location>
            <begin position="139"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="798" mass="90793" checksum="F4518955E16421DF" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDV8</accession>
    <name>A0A0C1KDV8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">lepA</name>
        <name evidence="7" type="ORF">DB41_CW00110</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000013">
        <property type="protein sequence ID" value="KIC77162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383287.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77162">
        <property type="protein sequence ID" value="KIC77162"/>
        <property type="gene ID" value="DB41_CW00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.153"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="7"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC77162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="602" mass="67486" checksum="31EEBE9B8B986295" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H087</accession>
    <name>A0A0C1H087_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CB00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000247">
        <property type="protein sequence ID" value="KIC71179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71179">
        <property type="protein sequence ID" value="KIC71179"/>
        <property type="gene ID" value="DB41_CB00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="8490" checksum="BA975889771D5AC3" modified="2015-04-01" version="1" fragment="single">FNEFEIALTVGISIYATKTFSLLYEEFKDKAFFEQRLQEVHIVGAQYYHAQDEKKRMMPSNDSIRNERRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H371</accession>
    <name>A0A0C1H371_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72029">
        <property type="protein sequence ID" value="KIC72029"/>
        <property type="gene ID" value="DB41_AA00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="222" mass="25273" checksum="4AD3A99C399793E4" modified="2015-04-01" version="1">MRVADPCGNSFLIQVDENAPFLEVLEGIQAHLVELDIAQKTAGSYLNGSEANPELSFNYTIGIPEICVNKGKHKVTRNYSRPVSTDEKNNIRYVIRSLAKYNLAQLAREKSSLERAGDKINHLHPFRFLQCIFNDEELKAGLHAIRKKGGYVWSNYYDGMKSSLNEEFDKDNLIQFTCDFADNVGVNVNEILPYVQARQWSNLVDVLINSIPRQGNPQRYDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H6Z7</accession>
    <name>A0A0C1H6Z7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JM00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386167.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73254">
        <property type="protein sequence ID" value="KIC73254"/>
        <property type="gene ID" value="DB41_JM00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="125" mass="14835" checksum="B86F116D6B0B8859" modified="2015-04-01" version="1">MVNTLTNADNHKNGTTISPNDSTVTSIKQLPDELLLHIFSFLQAFDLLEVELTCHRWKNLAEDETLWKELGRKHFEKYWVDEKPYKESYFVAHRVKRRYEKTMTFLGSLKQVERNFELAKYIGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H821</accession>
    <name>A0A0C1H821_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JH00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000164">
        <property type="protein sequence ID" value="KIC73549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244021.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000164.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73549">
        <property type="protein sequence ID" value="KIC73549"/>
        <property type="gene ID" value="DB41_JH00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="286" mass="33181" checksum="36D9FF6281259DA3" modified="2015-04-01" version="1">MRKIQLLVISLILLGGGWWLWSNKGDVKNIVTRYVENGEFQTLEARYTPQQIMDAHSRELLGDTSYQYKEPQYKYHPYLLMEVKFTADKKTREGVILWSLTDGEMVLNTETWERTHGFEDAINAQATREEFKILNALAKFNGIRTKEDLLADLQLEADVVNPWIESAIQKQLITRKGNLLQLHFENPKILVTPQTKFNRMLVSKPYNYSQRVSEKYTPSQIERVAKCAFGHDFSIRRITEVYLPVYAIHVENPDGSLTITHWNAVTGQMINPKYFKNGQERIKPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8I9</accession>
    <name>A0A0C1H8I9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BZ00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000245">
        <property type="protein sequence ID" value="KIC71193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71193">
        <property type="protein sequence ID" value="KIC71193"/>
        <property type="gene ID" value="DB41_BZ00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="102" mass="11694" checksum="FE1335B22EB36B1C" modified="2015-04-01" version="1" fragment="single">KSMHQLHRRGQRGQGLKRCACPAALQPKDWVQYIAFVIAIIVFNCPHHQPAKHDAVGEYAKHMQQLHTCISRLMEGIHTQQTFFTHSFHICLTTNVPTNHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H8V1</accession>
    <name>A0A0C1H8V1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BO00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000235">
        <property type="protein sequence ID" value="KIC71308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71308">
        <property type="protein sequence ID" value="KIC71308"/>
        <property type="gene ID" value="DB41_BO00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="6659" checksum="D9DAAC4F6212452C" modified="2015-04-01" version="1">MGSIGTSVAGAAITASFPAPAPALTVLAVGSVGLVFMATPVIMSAASLLVPTVGLWTGAAVALAGGFRGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9B3</accession>
    <name>A0A0C1H9B3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BB00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000222">
        <property type="protein sequence ID" value="KIC71468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71468">
        <property type="protein sequence ID" value="KIC71468"/>
        <property type="gene ID" value="DB41_BB00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039365">
        <property type="entry name" value="IS701-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038721">
        <property type="entry name" value="IS701-like_DDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33627">
        <property type="entry name" value="PTHR33627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13546">
        <property type="entry name" value="DDE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_5" evidence="1">
        <location>
            <begin position="9"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="109" mass="12371" checksum="106196FE2E8D6B84" modified="2015-04-01" version="1">MAKSMGVKKVLVLDDTSIPEKGKFSVGVARQYCGASGKIANCQSIVTWHYCEKGKEHFPILGALFLPQSWTKSKKRMQVAKVPKARYKFLKKWQLALQLLDDILKKDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9M7</accession>
    <name>A0A0C1H9M7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_AV00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386898.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71573">
        <property type="protein sequence ID" value="KIC71573"/>
        <property type="gene ID" value="DB41_AV00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC71573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="915" mass="96503" checksum="C4E797F99AEEA4CC" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H9R7</accession>
    <name>A0A0C1H9R7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpS</name>
        <name evidence="10" type="ORF">DB41_AV00330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="JRXI01000218">
        <property type="protein sequence ID" value="KIC71593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386940.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000218.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71593">
        <property type="protein sequence ID" value="KIC71593"/>
        <property type="gene ID" value="DB41_AV00330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2271"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="15"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="202"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="156"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="202"/>
            <end position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC71593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="360" mass="40837" checksum="BF3C7B8DCCF31B79" modified="2015-04-01" version="1">MSQSAKKRILTGDRPTGLLHLGHYVGSLKNRVAYQEHYECYLIIADLHMLTTKPTKEDILKMREHLKEMVLDYLACGIDPAKTTIYLQSATPAVYEMNLIFEMMVSLNRLIGLPSLKEMARNAHMDPESVPFGLVGYPVLQTADILMPRAHVVPVGKDNEAHVELARDIARRFNQLYGEVFPMPEASISDVPTLVGIDNKGKMSKSAGNCIFLSDDKKAVEKKVKSMYTDPHRIHAHQPGTVEGNPVFTFHEIFNPDKSEVEDLKKRYREGKVGDVEVKEKLAVALNLFLEPLRERRQHFAEEKGLIEEIIYEGTQKMIEVSNATVKEMRSAMGLMGNWNKISRIARERREKVASQSLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HB59</accession>
    <name>A0A0C1HB59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Signal peptidase I</fullName>
            <ecNumber evidence="3 5">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lepB</name>
        <name evidence="8" type="ORF">DB41_II00090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 5"/>
    <dbReference type="EMBL" id="JRXI01000142">
        <property type="protein sequence ID" value="KIC74624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243985.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000142.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74624">
        <property type="protein sequence ID" value="KIC74624"/>
        <property type="gene ID" value="DB41_II00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1574"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="77"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="527"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC74624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="628" mass="72478" checksum="D6891ED48FBFC04F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBM3</accession>
    <name>A0A0C1HBM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KR00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000197">
        <property type="protein sequence ID" value="KIC72193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72193">
        <property type="protein sequence ID" value="KIC72193"/>
        <property type="gene ID" value="DB41_KR00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="41" mass="4609" checksum="92178BCC4FC4CAB8" modified="2015-04-01" version="1">MDALVSHEACIDEDELKALFYFSKVKSVGQNKYLPIGYSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBZ4</accession>
    <name>A0A0C1HBZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nickel and cobalt resistance protein CnrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cnrA</name>
        <name evidence="4" type="ORF">DB41_KO00110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000194">
        <property type="protein sequence ID" value="KIC72323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72323">
        <property type="protein sequence ID" value="KIC72323"/>
        <property type="gene ID" value="DB41_KO00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1990"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="514"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="559"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="915"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="941"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="966"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1013"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1044"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC72323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1080" mass="118913" checksum="37507E0E846F367C" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HE83</accession>
    <name>A0A0C1HE83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dnaN</name>
        <name evidence="13" type="ORF">DB41_HH00270</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385231.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75734">
        <property type="protein sequence ID" value="KIC75734"/>
        <property type="gene ID" value="DB41_HH00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1225"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="129"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="245"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC75734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="378" mass="42363" checksum="47D7C9CFAC1BAC16" modified="2015-04-01" version="1">MKFVIATQELNYLINKCLNAVAQKSTIPILSNFLIEAINNELIITATDLTVGVRCFTEAKILEEGSTTLPAKRLAQLIRELTAMNVEITTSENEITEINAQTSRFKLNGMNKNEFPALPNVTDAVHFKIKQKILKDMLYRTAFAVSREDNRYVLTGVCLQVQGGTASFIGTDGKRLAKSQTTLNIDPSFQGTYVIPLKAVEEILKNLEEEGEAIVFLMQDKIAIKASNTTIISKLLAGEYPDVNRVIPSQTGITVNLHREELMTLLRQISLFAAENNHSVRFTFDEGELKLTANTMEIGEGKVSMPVNYKGEKLEIAFNPHFFLDILRHSKNETISLGITDPYNPGLISDFNYDQNEEEKESEQSSLFVLMPMRLSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HEN6</accession>
    <name>A0A0C1HEN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GX00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000109">
        <property type="protein sequence ID" value="KIC75904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384934.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000109.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75904">
        <property type="protein sequence ID" value="KIC75904"/>
        <property type="gene ID" value="DB41_GX00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="83" mass="9404" checksum="1C5FAD1A5E2E9E5E" modified="2015-04-01" version="1">MPHKAHTADERFIMCAYQALEALNDKEAPLNFYEVGEKAGITHKGVKAICKLLIQANFIKKISDEEIYLTQNGEQLALRLLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFK0</accession>
    <name>A0A0C1HFK0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="1">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mutY</name>
        <name evidence="3" type="ORF">DB41_JJ00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Adenine glycosylase active on G-A mispairs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="1"/>
    <dbReference type="EMBL" id="JRXI01000166">
        <property type="protein sequence ID" value="KIC73473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73473">
        <property type="protein sequence ID" value="KIC73473"/>
        <property type="gene ID" value="DB41_JJ00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDIX_4" evidence="2">
        <location>
            <begin position="44"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="153" mass="18060" checksum="4B62391AE2F5AB93" modified="2015-04-01" version="1">MECPLRSSCKGYRNGTAQQLPFKSTKVETSYLYRAVPIIIFDNKLLVKRGQKGEIMSDLHEFPYFETPPLGWSYQRLQEEMFLQWSLETQYIKELPQVKHSFTRYQASLKPVLFHSSYERPIADHTWLTHETLRQLAFSSGHRRIFMGLNLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFV9</accession>
    <name>A0A0C1HFV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GL00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384729.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76264">
        <property type="protein sequence ID" value="KIC76264"/>
        <property type="gene ID" value="DB41_GL00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="72" mass="7985" checksum="A59566C72BCC7381" modified="2015-04-01" version="1">MSNLMLTVFIAFVIVLISLALLGISWWFTGRIKIKPGACGRTPRQLQKEKCTEESASCGLCKRGGKKDELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGE8</accession>
    <name>A0A0C1HGE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GC00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76434">
        <property type="protein sequence ID" value="KIC76434"/>
        <property type="gene ID" value="DB41_GC00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.828"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="196" mass="21947" checksum="B22506A207DEBBC3" modified="2015-04-01" version="1">MQNNQLTFIPAEIGRLSQLQTLDLENNQLISLPVGIGQLPQLQDLFLNNNQLTTLPAEIGQLPQLQMLSLENNQLISLPIGIGQLSQLQDLFLNNNQLTTLPAEIGQLPQLQMLSLENNQLTSLPLEIGQLSQLQYLNLNCNQLTVLPAEIGQLSQLEYLHLYNNQLTSLPAEIRQLSRLKQLNLTATSLPPFLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HGL5</accession>
    <name>A0A0C1HGL5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF374 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IY00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000156">
        <property type="protein sequence ID" value="KIC73808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244006.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000156.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73808">
        <property type="protein sequence ID" value="KIC73808"/>
        <property type="gene ID" value="DB41_IY00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07983">
        <property type="entry name" value="LPLAT_DUF374-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007172">
        <property type="entry name" value="DUF374"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04028">
        <property type="entry name" value="DUF374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF374" evidence="1">
        <location>
            <begin position="73"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="227" mass="26052" checksum="9330ED517B77C055" modified="2015-04-01" version="1">MKSIKRYFSHYLVPRVLAYAGKAFLKLLLMTCRIQLEGLEEFCKHAKQGNCILMLWHNRLMLVATIFQSYTPQFNYTAFISQSRDGEPLALFANSFKNGRTIRVKHNAKHEALKEMINRLKNSLDIVLITPDGPRGPRYQVKPGLALAAKQTAATVFPFSWSASRLWQLKSWDKMMLPQPFSKICMTIGSPISYPAHINLDHYSHMLENALIDTDQSAYLKFSNRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH54</accession>
    <name>A0A0C1HH54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low calcium response locus protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lcrH</name>
        <name evidence="3" type="ORF">DB41_FI00240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76614">
        <property type="protein sequence ID" value="KIC76614"/>
        <property type="gene ID" value="DB41_FI00240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.697"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005415">
        <property type="entry name" value="T3SS_Ca_resp_chp_LcrH/SycD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01595">
        <property type="entry name" value="SYCDCHAPRONE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02552">
        <property type="entry name" value="LcrH_SycD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="189" mass="21893" checksum="0A644656CB0321EE" modified="2015-04-01" version="1">MKCFIDKVKKKFIISAPTGLKMESDDIGEFKITKKVKMKLKNKKLLKKQLAQGKTAQQILEFSDETMVKFYGAAYRLFDHRRYVEAAQAFLFLVTLNPYNHEYWVGLGMCSQLNKDYEAAIDAYEMAAICRIDNPVPYFYLAKCLFALHDRESALQALDLAIEYASNHPEFLELQHHAENAKRLLLKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH90</accession>
    <name>A0A0C1HH90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FB00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000064">
        <property type="protein sequence ID" value="KIC76669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76669">
        <property type="protein sequence ID" value="KIC76669"/>
        <property type="gene ID" value="DB41_FB00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="269" mass="29790" checksum="3EC6C1859BFC4D26" modified="2015-04-01" version="1">MVKRSLPVRRKVPTPSLALVTGATSGIGYALCEVLAAESIRLIISGRHLVQLEKAAQVLRQKVSVEIVAADLSTSEGRQAVVKIIRQQAPDLIINNAGFALYNEAINYSTEQQMQILEVNSVALLELSLEAAKAMEKANKTGIIMNVSSVAAFFTFPYLSVYAASKSFVNKLSYSLDYELRPKGIRVLVACPGMVDTNFRIRAGGNPAINKKGIMTSQFAAEQIWKQIKSLKTVNVFNWKYRLAVLFRHFIPNFISIKILANNIKKRCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHC0</accession>
    <name>A0A0C1HHC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76699">
        <property type="protein sequence ID" value="KIC76699"/>
        <property type="gene ID" value="DB41_EY00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="54" mass="6471" checksum="3151C551892A7A1F" modified="2015-04-01" version="1">MEDLQNFPPFVSKAKIWVYYTLSSNSLCKPLLYKTILLGREATYKEWACRRCFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHL0</accession>
    <name>A0A0C1HHL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EI00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76799">
        <property type="protein sequence ID" value="KIC76799"/>
        <property type="gene ID" value="DB41_EI00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.497"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="48" mass="5429" checksum="7770A0D3523CF9F3" modified="2015-04-01" version="1">MFKELQKVFQIPELRAKILFTILMLAVYRVGGFIPVPGINGEVAVSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHU5</accession>
    <name>A0A0C1HHU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DW00060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000038">
        <property type="protein sequence ID" value="KIC76894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383681.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000038.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76894">
        <property type="protein sequence ID" value="KIC76894"/>
        <property type="gene ID" value="DB41_DW00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="257" mass="28279" checksum="4D924E7D0D69F12C" modified="2015-04-01" version="1">MSSLTPNSQVSQNDSAAIPLAASPHQPSNLKKNFYSFTVKTIVFGATAATVLLAIKCIKQEQITLIDPRILNNFESKFIAISSEKIIATAVGACALLALEVYKKNKMVEQLAVRNLELQEEVNILTTTLQEKATEIQQLNQSLAIPSVSSEVEPTLIPPSLIESTPWIRTDTCYEVLATPPKKPPLIPPTPATHAARILRVLYNDELNVENNEQTLPEEVEDEISSTPFSSPHSTPPTPSKDAARHLRKIFSEEPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIC3</accession>
    <name>A0A0C1HIC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DL00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77024">
        <property type="protein sequence ID" value="KIC77024"/>
        <property type="gene ID" value="DB41_DL00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="66" mass="7591" checksum="C0E71ACC96ABBA45" modified="2015-04-01" version="1">MAKTLALAKPCDAKHRKHRLFENFKGRENEILNLTDFLFTLKLRKISSLDKQALILASADKFTDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIJ6</accession>
    <name>A0A0C1HIJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA recombination protein RmuC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rmuC</name>
        <name evidence="6" type="ORF">DB41_DC00010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383374.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77084">
        <property type="protein sequence ID" value="KIC77084"/>
        <property type="gene ID" value="DB41_DC00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.214"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="48"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC77084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="476" mass="54435" checksum="6C3BC74543299795" modified="2015-04-01" version="1">MDYLVDGVLALVIGALGVSFIWTLLKCKDKQSEKALWMEKCRVLEQQGREWRESLESKEIQLQNFREENSFQRSKIVELETQLTHQAQQMQEKLELLDQAQQKFTDTFNALSAEALKSSSQMFLELAAARFEKLQEGAKGDLKMREAAIDELVKPIKEKLEKFDSKIEDLEKSRVSAYATLTEQVKSLYTANAQLQQETANLVKALRMPHVRGRWGEIQLRRVVEMAGMVEKCDFLQQESSTQDERRLRPDLIINLPNNKQIVVDAKSPLQAYLEALEMPNETDKIMKLKEHAKQVRTHINQLSAKAYWDQFQPAPEFVVLFLPGETFFSAALEHDPSLIEHGVDQQVILATPTTLIALLRAVAYGWRQELIAENAQAISQLGRQLYDRLQVMSEHFEDVRKGLTRAVEAYNKTVGSFEGRVLVTARKFKDLGVGGQNEIELLETVDLKTRRSTNMPTNISELEESPLQTRLSVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIW1</accession>
    <name>A0A0C1HIW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CS00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000009">
        <property type="protein sequence ID" value="KIC77204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77204">
        <property type="protein sequence ID" value="KIC77204"/>
        <property type="gene ID" value="DB41_CS00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="119" mass="14057" checksum="AEAF46715C5D4BAD" modified="2015-04-01" version="1">MLTLNKVIERKNMQIKLLINPRNQGIAAELIPGVEIKIHEKWMLDAITASGITVSKEFKEQYHTGWYIYPTEDKAIFAKVFEQFYFAHGLQQQGYYWREKDEYDQLSLEEKLAKIIMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HK04</accession>
    <name>A0A0C1HK04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_IE00040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000139">
        <property type="protein sequence ID" value="KIC74838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385877.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000139.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74838">
        <property type="protein sequence ID" value="KIC74838"/>
        <property type="gene ID" value="DB41_IE00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="520" mass="60863" checksum="CBF66E029CE56E10" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HL59</accession>
    <name>A0A0C1HL59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">DB41_HV00100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000132">
        <property type="protein sequence ID" value="KIC75138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385460.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000132.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75138">
        <property type="protein sequence ID" value="KIC75138"/>
        <property type="gene ID" value="DB41_HV00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC75138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="204" mass="22512" checksum="185304E99281EB4E" modified="2015-04-01" version="1">MIGSSCVFISNSFNFFLVTNPIGNSPTILALVKDFEFEHQKKILMREGLIAFLIAIFFQYLGEILLGVLFVHDFAVSITGGILLFLVALRMIFSTAPSTKSANQQKQEPFIVPIATPILSGPGLMAIIMLFSRQEGNNIKITLALLLAWIFVLLIIAVAPYLHKLLGKRGLVALEQLMGMLLAMMSAGMVLTGLKLFIEHYKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLS6</accession>
    <name>A0A0C1HLS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HO00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000125">
        <property type="protein sequence ID" value="KIC75353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75353">
        <property type="protein sequence ID" value="KIC75353"/>
        <property type="gene ID" value="DB41_HO00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="43" mass="4851" checksum="33B872ACF58C2D73" modified="2015-04-01" version="1">MIFAFQKPAPEQLRVSKELKKQGCFISPGMCVRLVSLPKKCVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HLU9</accession>
    <name>A0A0C1HLU9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MlaD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HN00050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385349.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000124.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75373">
        <property type="protein sequence ID" value="KIC75373"/>
        <property type="gene ID" value="DB41_HN00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1282"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="3">
        <location>
            <begin position="38"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="358"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="395" mass="44466" checksum="928195F519B3453F" modified="2015-04-01" version="1">MTDPLKNIMIGIFVVTAMAVIVFALMFLHPSLGDEKRVLRVRFPNIDKISVGTRVSFAGKPVGEVAAIHEIKDAIESRQPYQGIIYVYELVLHVDSNVNVFSTDEISVRTSGLLGERSVVIIPFPSKAGKPLHLVNEEILYATEAGSVEDTLKEFKELAGKFDTSLNSISTVFNEMSEEKIVKKLGMAIQNVNSITHALNQPLQLSQMIKNAHTLTEKVLTLWDRVEGMLSNLSAASHNLRLLTDKGSNILSYVEKGQGTLGKLLMTDQLYLKANSFLSKGETMMNDINHYGLLFNMDKGWQRLRARRLNLLSTLSTPQEFRNFFNQEIDQINTSLSRVYALAEQSHGSSSGCKLFENQEFQKVYRELLRRVADTEEALKMYNQQLIDMNAKKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNG3</accession>
    <name>A0A0C1HNG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GZ00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384964.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75853">
        <property type="protein sequence ID" value="KIC75853"/>
        <property type="gene ID" value="DB41_GZ00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="521"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="571" mass="63477" checksum="7153C473311D2753" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNR3</accession>
    <name>A0A0C1HNR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GW00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000108">
        <property type="protein sequence ID" value="KIC75933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75933">
        <property type="protein sequence ID" value="KIC75933"/>
        <property type="gene ID" value="DB41_GW00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6900" checksum="462476F4EB52FF58" modified="2015-04-01" version="1">MQNKQIFIYSMFYLICICFLFACYRLPREDEYSVVPSTNNPEVIREKQPNNFAPNVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQE5</accession>
    <name>A0A0C1HQE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GF00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000091">
        <property type="protein sequence ID" value="KIC76413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384589.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000091.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76413">
        <property type="protein sequence ID" value="KIC76413"/>
        <property type="gene ID" value="DB41_GF00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="71" mass="8360" checksum="B0A78F1F4E65D4F5" modified="2015-04-01" version="1">MADDAKFALIPEVRGLGKKCLEDWAKHQVNEQEAKAREMKLRQHSKKAKLTYNIWDSRYGREMLPTSRKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQR0</accession>
    <name>A0A0C1HQR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FW00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000083">
        <property type="protein sequence ID" value="KIC76513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76513">
        <property type="protein sequence ID" value="KIC76513"/>
        <property type="gene ID" value="DB41_FW00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="75" mass="8442" checksum="CE5303D29E3C8E61" modified="2015-04-01" version="1">MHLLIYIKQGNIKQAAEYTKKALRSSIAMHGIHHPAIAAINSDLQVLNLLVSTTFVKTNYCHKRRDKLTGRKALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HQV6</accession>
    <name>A0A0C1HQV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FQ00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000078">
        <property type="protein sequence ID" value="KIC76548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384310.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000078.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76548">
        <property type="protein sequence ID" value="KIC76548"/>
        <property type="gene ID" value="DB41_FQ00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="352" mass="40739" checksum="9DA7E792602D337E" modified="2015-04-01" version="1">MNPSININTAPGITAVNTNMQLMQPIRQLEVQDIKEAVELCLDNEGVILLEEYQEMSLKKLEEHFKKQIDEFFECDKAAQAMLKNNADSLEYSQCVSEAEKKVENINNIINALSSMQQYTESYNLQQEKVVRLLQDMRSSIPLGNSIILRKDIEMMRAISSIPQDKIYFSPAQGTFYEPQISAAELAGWFHKQIIEECYEGVSIARKMDCMYSYQLNTMCTIIGLKKKKNKGGEEMIKKRSSFRKTIKGYTSKADKQEMESLSSKWRKLYDYASAYYESMLRHSKEKSLEEVKVLQTTVLKEISKELPNMLTQWKYEKCEVGTSEELIKKYGASPNIAREADYIILFHIKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HR92</accession>
    <name>A0A0C1HR92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">kas1</name>
        <name evidence="14" type="ORF">DB41_FH00190</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="JRXI01000069">
        <property type="protein sequence ID" value="KIC76638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384131.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000069.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76638">
        <property type="protein sequence ID" value="KIC76638"/>
        <property type="gene ID" value="DB41_FH00190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.673"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="6"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KIC76638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="415" mass="44156" checksum="E001AFD5363CBB6C" modified="2015-04-01" version="1">MKKKRIVITGMGIVSCFGNEVNDYYQSLLDGKSGASLITSFPCEDYPTRIAASIKNFESGDYIDKKQARRIDKNIAYAMVAGKKALEASQLSPEIIAKLNKERCGVVIGSGMGGMDVYCQGVQTLIQKGQRWVSPFFVPYILTNMGGAMLAMDIGFMGPNYSVSTACATGNNAIIAAANHIRKGEADLMICGGSEAPIIPMGLSGFCSCKALSQRNDEPEKASRPWDRGRDGFLMGEGAGTFIIESLEHALARGAPIIAEYLGGGMSCDAYHITEPRADSEGVALCVRNALADAGIKAEEVDYINAHGTSTPAGDMAEVRALKKVFKEPSSIIMNSTKSMIGHCLGAAGAMEAVVTAKAIESGWVHPSINLEDPEPDLEFHIPTVAEKKDINIAISNTFGFGGHNATIVLGAYHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRP5</accession>
    <name>A0A0C1HRP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">rplO</name>
        <name evidence="8" type="ORF">DB41_EI00130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383822.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76798">
        <property type="protein sequence ID" value="KIC76798"/>
        <property type="gene ID" value="DB41_EI00130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.496"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="7">
        <location>
            <begin position="29"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="149" mass="16467" checksum="042FFE4F6878ED29" modified="2015-04-01" version="1">MTSLDKLQDVSRERKKRRRVGRGIGSGLGKTCGRGEKGAGSRSGYKRRLGYEGGQFRLFMKLPIRGFSNARFSNKYETVNLGQINEMYSDGETVNAQTLAEKGFVRGKIRGIKILGDGELNKKVKIEVKAVSSAAQEKLQKAKIAIEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRV2</accession>
    <name>A0A0C1HRV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">POLIIIAc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EE00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000044">
        <property type="protein sequence ID" value="KIC76848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76848">
        <property type="protein sequence ID" value="KIC76848"/>
        <property type="gene ID" value="DB41_EE00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.453"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="9733" checksum="9947D2003E3570F8" modified="2015-04-01" version="1">MWVPLHVHSQFSILDAAADVHAIAKKAAFFHMPAVALTDHGNMFGAIDFYKACKDVGVKPILGCEFYVAPDSRFDKKKNMEHVLIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HS41</accession>
    <name>A0A0C1HS41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">fusA</name>
        <name evidence="8" type="ORF">DB41_DT00070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000035">
        <property type="protein sequence ID" value="KIC76913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383650.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76913">
        <property type="protein sequence ID" value="KIC76913"/>
        <property type="gene ID" value="DB41_DT00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.396"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="10"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="83"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="137"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="695" mass="77435" checksum="DD0F3FA8DD9083F1" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSJ8</accession>
    <name>A0A0C1HSJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DK00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000027">
        <property type="protein sequence ID" value="KIC77038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77038">
        <property type="protein sequence ID" value="KIC77038"/>
        <property type="gene ID" value="DB41_DK00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="93" mass="10282" checksum="06587BF57B43146B" modified="2015-04-01" version="1">MILGVSVFSCPHNRRSLVQIQVAPLFYQYSRALLSNIQLEIIKRHTPCSGKHAAQKLERITINRVDKPVMANGRCRLHGGKSTGAKITEGSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-12-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSU4</accession>
    <name>A0A0C1HSU4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tlcA_2</name>
        <name evidence="10" type="ORF">DB41_DB00100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ADP/ATP translocase tlc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000018">
        <property type="protein sequence ID" value="KIC77103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383352.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77103">
        <property type="protein sequence ID" value="KIC77103"/>
        <property type="gene ID" value="DB41_DB00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.201"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004667">
        <property type="entry name" value="ADP_ATP_car_bac_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31187">
        <property type="entry name" value="PTHR31187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03219">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00769">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC77103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="522" mass="58910" checksum="D42CF12F4E92C704" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSX5</accession>
    <name>A0A0C1HSX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein YlbG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ylbG</name>
        <name evidence="1" type="ORF">DB41_CX00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000014">
        <property type="protein sequence ID" value="KIC77148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77148">
        <property type="protein sequence ID" value="KIC77148"/>
        <property type="gene ID" value="DB41_CX00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="5744" checksum="1F1DA39DE04CDC34" modified="2015-04-01" version="1">MMGYSRDSLCRFKELYETGGGAALQDTTRKEPCIKNRVDESIEKAVVDFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JK27</accession>
    <name>A0A0C1JK27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AT00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000216">
        <property type="protein sequence ID" value="KIC71640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386842.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000216.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71640">
        <property type="protein sequence ID" value="KIC71640"/>
        <property type="gene ID" value="DB41_AT00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="196" mass="22896" checksum="7D2DC0D4D2E7298A" modified="2015-04-01" version="1">MLNEVNKEIKKQNDNKDKGIKNPLKFNIRGKENSHTIKKFTSFQAACIEKEKIEREENFNRLEIVYDYEGNGWKLKETSYNCIMWAKNKLASMNISLYGGTNFLFSPLAGIIPLIEEISHKALKAAIKSLCEPLVSSLLLETPCDYIKLNSKRKYKELRNQQNLFHHLIVGKRAFLNKQDFDIINEIIRIMFRPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL25</accession>
    <name>A0A0C1JL25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AC00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000203">
        <property type="protein sequence ID" value="KIC71990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71990">
        <property type="protein sequence ID" value="KIC71990"/>
        <property type="gene ID" value="DB41_AC00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="8094" checksum="CF986138101CA3BD" modified="2015-04-01" version="1" fragment="single">MIRKPYPSDLNNQEWQVLEPIICKKKAGKPPMHSRREMLNAIFYVLRTGCQWIDLPHDLPPWKSVYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL31</accession>
    <name>A0A0C1JL31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BP00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000236">
        <property type="protein sequence ID" value="KIC71286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71286">
        <property type="protein sequence ID" value="KIC71286"/>
        <property type="gene ID" value="DB41_BP00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="59" mass="6755" checksum="B9F4E043786C5C8E" modified="2015-04-01" version="1">MEERCFLQAGKLIRPFSFYSKVRCRGYSLPLERAITDFGADIAFGKLGETCLLPKWRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN75</accession>
    <name>A0A0C1JN75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_KE00020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000186">
        <property type="protein sequence ID" value="KIC72685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244044.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000186.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72685">
        <property type="protein sequence ID" value="KIC72685"/>
        <property type="gene ID" value="DB41_KE00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1885"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="424" mass="48573" checksum="6FC1A8A6E1B3512D" modified="2015-04-01" version="1">MHPLSSTSIESLPNELLLPILEACAVPSLFSVCKRWHYLLASEVMPSLYKKIAQLHFPRKNITTQRTLLLAKVYQLNPALTSTEKVYQVFKQVFTLAKSISPLEFKEKTEEKIGLTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEKKRGLLRDWIEENGKNIMALDLSRVGLTYLPQEICQLSQLQWLDLRENQLTALPTEIGQFSQLQWLNLIQNQLTSLPTEIGQLSQLQVLELNQNQLTSLLTEIGQLSQLRRLVLNQNQLTNLPAEIGQLSQLQTLDLNQNQLTALPAEIGQLSQLQTLDLNQNQLTALPAEIGQLSQLQWLNLSKNQLTRLPTETGQLSQLQWLYLNENQLTALPTEIGQLSELRELYLNENQLTSLPAEIGQLSQLRRLELAENPLKDIDEKIRQRFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JN96</accession>
    <name>A0A0C1JN96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KD00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72705">
        <property type="protein sequence ID" value="KIC72705"/>
        <property type="gene ID" value="DB41_KD00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="55" mass="6264" checksum="2D2D553AB58B924C" modified="2015-04-01" version="1">MLYGLSLLYSASSALANSKSKCFFSFYKNFLVECFDFTYNHSLSLSIRLPKILPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNM2</accession>
    <name>A0A0C1JNM2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">ung</name>
        <name evidence="12" type="ORF">DB41_KU00120</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386541.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000199.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72116">
        <property type="protein sequence ID" value="KIC72116"/>
        <property type="gene ID" value="DB41_KU00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2058"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="52"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC72116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="229" mass="26266" checksum="2069AA8FA62B52F1" modified="2015-04-01" version="1">MTGFELGLSWQKALKDELQKPYLQELEAFVERERFQGFNVFPPRELVFNAFRMTPYESVRVVIMGQDPYHGPRQAHGLSFSVPEGVRPPPSLQNIIKELNADVQIPMPKHGCLIHWAEQGVLLLNATLTVRQGEPLSHHGKGWERFTDAVIEHLVNGRENLIFILWGKSAQEKCRHIIASHEEKKHHILMAAHPSPYAAQQGFFGCRHFSKVNDILRTKKQEPIDWAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPZ3</accession>
    <name>A0A0C1JPZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JL00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000168">
        <property type="protein sequence ID" value="KIC73285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73285">
        <property type="protein sequence ID" value="KIC73285"/>
        <property type="gene ID" value="DB41_JL00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="363" mass="41763" checksum="8781288E6F390091" modified="2015-04-01" version="1">MAIEILPSLYKKIAAMHVINGNEKQRTHLLDKIYQLDSKLATAEKVDRIFKQVFTLAKSLSPLEFKNKTEEKRYLTLANYSSYLLNINRLLIWEKIPEGKEYLAQEEIKLLSLEEKGKLFSQWIESYGKGIKVLDLSRLGLTYLPPEIGMLSALVSLNLSQNQLTFLPKEIGQLTLLQNLNLSQNYLTFLPKEIGLFLQLISLNLNENQLTCLPKEIGDLHWLRHLNLSNNHLVSLPKEIQQLSRLYSLNLNQNQLSFLPREIGLIPGLGWLYLNHNQLTSFAMESGLFSQLYSLSLSHNQLTSFVIAMRQLFPMQNLDLSYNHLNTLPTSIDQLPQLLSLKTQGNPLENIPEEIRQRFPPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JQN8</accession>
    <name>A0A0C1JQN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative AMP nucleosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">amn</name>
        <name evidence="2" type="ORF">DB41_JI00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000165">
        <property type="protein sequence ID" value="KIC73520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73520">
        <property type="protein sequence ID" value="KIC73520"/>
        <property type="gene ID" value="DB41_JI00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1757"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010944">
        <property type="entry name" value="AMN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011271">
        <property type="entry name" value="AMP_nucleosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF6">
        <property type="entry name" value="PTHR43691:SF6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01721">
        <property type="entry name" value="AMN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="80"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="294" mass="33308" checksum="9C6BE69F1C7736F5" modified="2015-04-01" version="1">MTLINKVNLMEEDCNYNFNVNPLEEKIATDTLERYSGSTVQDFQPYLLLTNFPRYVRQFANDRNLPILEGSMFSVAHSPKEKVSILDFKIGSAAAALIIDLCAFLPIRAALLLGMCGGLRKHHKIGDYFVPVAGIRGEGTSDFYFPQEVPSMANFLVQKCVSNVLDRQNSTYHIGITHTTNKRFWEFNENFKSRLEKTRPQAIEMECATLFMASYYHKLPLGALLLISDLPLGKDGVKTKQSSEKVYQEYTIDHVDKGVKIMLELDATLNHQAKGVFRGARRRFESPKVAITDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JR72</accession>
    <name>A0A0C1JR72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_JV00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000178">
        <property type="protein sequence ID" value="KIC73011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73011">
        <property type="protein sequence ID" value="KIC73011"/>
        <property type="gene ID" value="DB41_JV00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="68" mass="7857" checksum="4189173362511209" modified="2015-04-01" version="1">MFRLERKNTKNAARHGEQMNPLLHAHTSTKVNKRRAYLSKKVISRTRKIGFFLPGEKSPSSSARKTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JS10</accession>
    <name>A0A0C1JS10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_JM00140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000169">
        <property type="protein sequence ID" value="KIC73261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386173.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000169.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73261">
        <property type="protein sequence ID" value="KIC73261"/>
        <property type="gene ID" value="DB41_JM00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC73261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="859" mass="97019" checksum="0FB38ED509758BF5" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JS30</accession>
    <name>A0A0C1JS30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide core biosynthesis glycosyltransferase WaaE</fullName>
            <ecNumber evidence="2">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">waaE</name>
        <name evidence="2" type="ORF">DB41_JL00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000168">
        <property type="protein sequence ID" value="KIC73286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386157.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000168.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73286">
        <property type="protein sequence ID" value="KIC73286"/>
        <property type="gene ID" value="DB41_JL00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1773"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC73286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="249" mass="28540" checksum="C4093EFB49BD1FDD" modified="2015-04-01" version="1">MIPISVTILTKNSCQYLAQVLDSVSLFDEVLIYDTGSVDDTIKIAKSYSNVRVILATFEGFGPTHNKASAYAKHDWILSLDSDELATPAMIQEILATSLQEKVVYSFPRHNYFNNKFIRWCGWYPDRQYRLYNRKETGFTNVQVHEAIIVKHMQHVPLNSPLIHYSYNSIADFLSKMQTYSTLFAEQNKGKKTASLSKALTHGIFSFLKSYILKRGFMGGYEGFIISAYNGHTAFYKYLKLYEANRKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JT72</accession>
    <name>A0A0C1JT72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-oxoisovalerate dehydrogenase subunit beta</fullName>
            <ecNumber evidence="2">1.2.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bkdB-B</name>
        <name evidence="2" type="ORF">DB41_IQ00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000148">
        <property type="protein sequence ID" value="KIC74305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386040.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000148.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74305">
        <property type="protein sequence ID" value="KIC74305"/>
        <property type="gene ID" value="DB41_IQ00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1658"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC74305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="325" mass="36133" checksum="7ECEA4DB91FF89FB" modified="2015-04-01" version="1">MAIMNIIQSLNHTLHQEFARDSRLLTFGEDVGAFGGVFRVTTGLQEKFGEERCFDTPLAEAGIIGFGIGIAQKGLKPICEIQFADYIYPAFDQIVNEMAKMRYRTGNQYSSAMVIRTPYGGGIHGGHYHSQSPEAFFLHIPGLVVAVVSSPYDAKGLLASAIRSNDPVLLLEPKRIYRSLKQEVPEEEYLIPFGQAHVERTGRDITLIGWGAQHHQNKQAAEELAQQENIDVEVINLRTLNPLDIHTLVASVNKTGRCVVCHEAPLTQGFGAELSALIHERCLLKLQAPVKRCCGLDTPFPHTLEKEYLPDTPRVKKAILETLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV10</accession>
    <name>A0A0C1JV10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">mnmA</name>
        <name evidence="8" type="ORF">DB41_IR00060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74236">
        <property type="protein sequence ID" value="KIC74236"/>
        <property type="gene ID" value="DB41_IR00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1666"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with target base in tRNA" evidence="7">
        <location>
            <begin position="99"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="309"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC74236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="378" mass="42516" checksum="5FFA15EFEA15F0D5" modified="2015-04-01" version="1">MMIPNRQKTVVVGMSGGVDSSVAALLLKQQGYHVIGMFMKNWEETDEHGTCKASYEYEDVVRVCEQIGIPYYAVNFVKEYKENVFNQFLEEFKQGYTPNPDILCNREIKFKVMFEKALALGADYLATGHYCQSFTHDEESILAKGIDSGKDQSYFLYTIKSHVLSKVLFPVGNLHKPEVRKIAQEHCLATSAKKDSTGICFIGERNFKQFLSQYIAYRPGNFETLEGQVIGIHDGVAYYTIGQRRGMGIGGQGEPWFVVGKDLERNVVYIERGAHHPALFCDELVACEASWVSPHGRSTLPLACRAKVRYRQTDQACTIMTETDGQLKVVFDVPQRAVTPRQSIVFYEGEKCLGGAIIQSAGVSYYHQNKALPKHISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV65</accession>
    <name>A0A0C1JV65_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glgA</name>
        <name evidence="10" type="ORF">DB41_IB00880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385779.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74955">
        <property type="protein sequence ID" value="KIC74955"/>
        <property type="gene ID" value="DB41_IB00880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1524"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="305"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KIC74955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="508" mass="58554" checksum="AF1CD38AC666BB9C" modified="2015-04-01" version="1">MHIINIASELAPIAKVGGLGDVLLGLSRELSCKGHDIDLIIPKYDCMDTESIRDFAIYNDSLPSFYKGTWHRNTIWKGWVENLKVYFIEPHHPAHFFHRGCFYGCADDMERYLYFSRAALEFIEKEGLSPHIIHLHDWQTAVIAPLYHELYRPQCVKEAKIVFTIHNIEYQGHCSSSDLDNIGLNGSHYLLPDKMQDAQYKEAINLLKGAIIYADHITTVSPNYAKEVLTPLGGRGLDKTLYKYQSKFKGILNGIDYSYWNPEIDRYLPTHYSPRETPESKKDRHTLDKKAYIKNFLRERLFLAEEHRPIVGCIARLVPQKGIELIKHALHYTLEKKGQFLLLGSSPIEGINAEFQQLNRHFHEHPHVRLILHHSEELAHLIYAASDMFIVPSLFEPCGLTQMIALKYGTIPIVRKTGGLADTISDVDYSGKPIEKTNGYVFEYPDAKGIESALDRAFECWFHYPDRWRQLIIRAMKTDFSWNTPSDEYLNIYQSILATEKEAKKSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JV91</accession>
    <name>A0A0C1JV91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CD00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000249">
        <property type="protein sequence ID" value="KIC71172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71172">
        <property type="protein sequence ID" value="KIC71172"/>
        <property type="gene ID" value="DB41_CD00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="45" mass="5304" checksum="E066E553F2252F02" modified="2015-04-01" version="1">MRQKEPFLLNKAKNHSSFSQTKIAVSLNRQNLWLLLNAWKAPHFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVB6</accession>
    <name>A0A0C1JVB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_BY00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000244">
        <property type="protein sequence ID" value="KIC71202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71202">
        <property type="protein sequence ID" value="KIC71202"/>
        <property type="gene ID" value="DB41_BY00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="44" mass="4988" checksum="2B80B1868CE55FAD" modified="2015-04-01" version="1">MYVVLPMLKWLVFHHHPQPLMRCCLGHAEVLDVAGSNELGVKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVB8</accession>
    <name>A0A0C1JVB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">asd</name>
        <name evidence="2" type="ORF">DB41_HY00310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385559.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75005">
        <property type="protein sequence ID" value="KIC75005"/>
        <property type="gene ID" value="DB41_HY00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1425"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="1">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="358" mass="39624" checksum="FC87A2FD6B989BB2" modified="2015-04-01" version="1">MKKIPVGILGATGMVGQQYLQLLSKHPWFEVVFLASSKQSAGKSYAEAVQNRWLPNTPLSETHGKLPVYSIENIEQCKRDCSLVFSAVDSPIAKLYEESYAAAGLPVMSNTSYHRNTPDVPLLIPEINAHHLSMIKEQQKNRGWTQGCIVVKPNCSLQSYMIPLQPLHQKFQVKKLMVTTLQAVSGAGYPGVSSYAIQDNIIPYIEGEEQKSESEPLKIWGNIQEDRIVNASGISLSVTCNRVPVLDGHMACVSVEFATKPSLEDILQAWQTFKGAPQDLHLPSAPLCPVVYHDEKDRPQPRLDRLEGNGMSIVAGRLRECPLFHYRFTALSHNTIRGAAGGGILTAELVYQQGYIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVC6</accession>
    <name>A0A0C1JVC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HX00040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000134">
        <property type="protein sequence ID" value="KIC75020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75020">
        <property type="protein sequence ID" value="KIC75020"/>
        <property type="gene ID" value="DB41_HX00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="52" mass="6102" checksum="ED67A22724E5A2AC" modified="2015-04-01" version="1" fragment="single">MLKKAWKYLFTFAKLKIESCHKNPSLYYKNQSFLFLIPLNGNFPNSIAAYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWA0</accession>
    <name>A0A0C1JWA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_HN00020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75370">
        <property type="protein sequence ID" value="KIC75370"/>
        <property type="gene ID" value="DB41_HN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1187" mass="132479" checksum="873E10902FEB87A9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWA4</accession>
    <name>A0A0C1JWA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative periplasmic immunogenic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_HN00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000124">
        <property type="protein sequence ID" value="KIC75375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75375">
        <property type="protein sequence ID" value="KIC75375"/>
        <property type="gene ID" value="DB41_HN00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002147979" evidence="1">
        <location>
            <begin position="21"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="237" mass="26050" checksum="BBBA910C5DC9F83E" modified="2015-04-01" version="1">MMFKVLTPLLCLFLCTFARAAETPTLSLKGQAVLHKQADQISLIIGITNLGAEADHVLAENSKKMQNLIGELNKKGFDKSEYQTGQFSIQPTYTLPPQNPPAGWRPTINGYEVSNILKIKTDKIKEIGALIDTAHQAGASKIDHIYASLKDERAYWEEAVAKATKNAIADAKIMAEAAQVKLNRLLSISLNDTLARSPQSLTPMFLKTMASELTPIEPGDIEIKANVNVVYEIDKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JX17</accession>
    <name>A0A0C1JX17_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 16" type="primary">rpoB</name>
        <name evidence="16" type="ORF">DB41_HY00020</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC74976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74976">
        <property type="protein sequence ID" value="KIC74976"/>
        <property type="gene ID" value="DB41_HY00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1397"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="13">
        <location>
            <begin position="22"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="12">
        <location>
            <begin position="296"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="14">
        <location>
            <begin position="459"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="15">
        <location>
            <begin position="537"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="10">
        <location>
            <begin position="663"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="11">
        <location>
            <begin position="1175"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="881"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KIC74976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="1254" mass="140983" checksum="B66AE5C3C8F96AD9" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXC1</accession>
    <name>A0A0C1JXC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">60 kDa outer membrane protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cysteine-rich outer membrane protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">omcB</name>
        <name evidence="6" type="ORF">DB41_HH00080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB).</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75715">
        <property type="protein sequence ID" value="KIC75715"/>
        <property type="gene ID" value="DB41_HH00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1205"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005201">
        <property type="term" value="F:extracellular matrix structural constituent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003506">
        <property type="entry name" value="Chlam_OMP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01336">
        <property type="entry name" value="CHLAMIDIAOM6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF11" evidence="5">
        <location>
            <begin position="225"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="5">
        <location>
            <begin position="332"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="5">
        <location>
            <begin position="442"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC75715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="554" mass="59396" checksum="82CEB02E7328320D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JXV7</accession>
    <name>A0A0C1JXV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_AA00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244083.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72037">
        <property type="protein sequence ID" value="KIC72037"/>
        <property type="gene ID" value="DB41_AA00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2091"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="389" mass="45195" checksum="DE7DE86057A7FE5F" modified="2015-04-01" version="1">MVKKVDLITPYGSQYRVLHHFTKKLYEAWIRAGYEARFFEDATEALKIMLLDPPDLVIGFNGVPRHDQIPYSDILKKPYLSLIVDPFYHFLSEISSPYVIIGCDDYSSVTAFKNTNFHQTLFVPHAVEADLATDPAVEKIFEVTMLATFIDYEARREQWRLKYPSQVCEAMHEAVEQTFLDPQLAFIEATLGKVQWAYSKHPELRTAEVDIISLLKDVELYIKGKERIDILKAIQTVPVHVFGHSVDKVNWKSYFKNQSNIITHDSVIYEKSIEIMKQSKIVLNSSIKNKFGAHERIFTALAAGALVITNENNYLKTFFSHDVDIAFYQYHRLLNLNQMIVDYLADEGHRQQVVENGREIVMNYHTWDARIREFEKDLFPRVEGCMLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY21</accession>
    <name>A0A0C1JY21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GV00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000107">
        <property type="protein sequence ID" value="KIC75950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75950">
        <property type="protein sequence ID" value="KIC75950"/>
        <property type="gene ID" value="DB41_GV00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="76" mass="8727" checksum="FA744F20486FD156" modified="2015-04-01" version="1" fragment="single">NTLIKSGEFSLPGKKALLEKESEYEVVLIDASESSVERPKRRRAKEKKDKKSQRQAEAFLFRKKEKAYPKKSGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JY31</accession>
    <name>A0A0C1JY31_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BFN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GU00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384877.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75960">
        <property type="protein sequence ID" value="KIC75960"/>
        <property type="gene ID" value="DB41_GU00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1029"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036104">
        <property type="entry name" value="BFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003729">
        <property type="entry name" value="Bi_nuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02577">
        <property type="entry name" value="DUF151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103256">
        <property type="entry name" value="SSF103256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51658">
        <property type="entry name" value="BFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BFN" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="138" mass="15782" checksum="57E2150C46AEE195" modified="2015-04-01" version="1">MLSELIQLSFDKIMQTRSYTVVILKGQGKKFAIYTDPAIGRNLQIFLTGAEKARPLTHDLISYIFRGYEIRLKQVVINDIQDTTYFARLFLEQDAGGRRHIVEIDARPSDCITLALMNNAPVFCTRDVLEKTLAIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ78</accession>
    <name>A0A0C1JZ78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HG00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000117">
        <property type="protein sequence ID" value="KIC75746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75746">
        <property type="protein sequence ID" value="KIC75746"/>
        <property type="gene ID" value="DB41_HG00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="50" mass="6072" checksum="90F13576ACF28018" modified="2015-04-01" version="1">MLDETREEKLYPKENNCVVVFSRRQGRSNIRGKLLSKPYLLGRIYFSYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZB9</accession>
    <name>A0A0C1JZB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HE00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000115">
        <property type="protein sequence ID" value="KIC75801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75801">
        <property type="protein sequence ID" value="KIC75801"/>
        <property type="gene ID" value="DB41_HE00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="58" mass="6867" checksum="B3F2F419F5298ABD" modified="2015-04-01" version="1">MKPIKLDNQQGRLFKSRFSDELDLNHPLIQLSKLIEWKQLEEEVDKLFVEKIGSQLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZV0</accession>
    <name>A0A0C1JZV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_FX00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76500">
        <property type="protein sequence ID" value="KIC76500"/>
        <property type="gene ID" value="DB41_FX00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.789"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="163" mass="18879" checksum="93DE021D2E6E92FB" modified="2015-04-01" version="1">MKHIKSERLKKLEVELNDLEQWLKLGLVPKKDMDKHKEEIRAIQTKIEEEKERLKFLKESGEAEEYIAPKRPTARAGYTEMPTIPDIDMGDTGAGIGDTAFDMETDAIDVESSVIEEKDETEDEEGATRDENAEEEEEEEESYFSDRNRWRRGGIIDPDADEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZV5</accession>
    <name>A0A0C1JZV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FX00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000084">
        <property type="protein sequence ID" value="KIC76505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76505">
        <property type="protein sequence ID" value="KIC76505"/>
        <property type="gene ID" value="DB41_FX00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="842"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="868" mass="99882" checksum="615B78157B10E08F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K000</accession>
    <name>A0A0C1K000_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_GP00020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000101">
        <property type="protein sequence ID" value="KIC76031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384823.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000101.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76031">
        <property type="protein sequence ID" value="KIC76031"/>
        <property type="gene ID" value="DB41_GP00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="506" mass="56810" checksum="E3FD69B45C56D56F" modified="2015-04-01" version="1">MLARPMKKYKIPSLISILAFLSLITINFTSCLKQRQPNIYEFPTRALEESLLSTINEGPFTPGEWPQAHWWLMFGDSQLDKLISKALSDNPGIKIAQARVKIANYAARAAGSALWPTLELETDIARSRTSKTGTIASIASSSPPASTFTTPPAFPTRSGGFIFTQTEINLDAHYQLDIWQQNLNSFKAAVGEILASKADAAFSSVILSTSIAQTYFRLQVSYAQKILALKKLHNRAEYLQLVEKRVKNDIDNQCVLKKAQTYHLEAQLLLKQVQLKIKAYKNQLQALIAGDFCEPIEAIAIENQDLFLFSLPTNLPFNLLAHRPDVTASVWRVEEAAKKIKVARAAYYPSFNILGLFGYQTLHPHDLFKWRSIYGQASPAINLPIFEGGLLQANLGTAHEEYYIAIEQYNQSILTAVQAVLDSIAELKYAFEEMQDSVQITKLSEENSLLIKEKFKHYLASYLDVLDAEFDKTSQENKKLVALENYYIRFTSLISALGGGYENESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K021</accession>
    <name>A0A0C1K021_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_FN00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76555">
        <property type="protein sequence ID" value="KIC76555"/>
        <property type="gene ID" value="DB41_FN00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="102" mass="11664" checksum="D63E141FF63192E6" modified="2015-04-01" version="1">MSFQGIRKKKYEIQQGLVADLAKEPQSPTQFLQLYRPLYVFWLSILILRHVYLAISLGPIIRIYAIKKIFIALKCKGEAGMLRAACSLTILLQLANVIQSVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K034</accession>
    <name>A0A0C1K034_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FN00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000075">
        <property type="protein sequence ID" value="KIC76565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76565">
        <property type="protein sequence ID" value="KIC76565"/>
        <property type="gene ID" value="DB41_FN00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="46" mass="5448" checksum="AC59F538CE71261A" modified="2015-04-01" version="1">MFKNVEELQEDVDKWMNEYNNERTHTGKYCLGKTPLETFLDAKPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K052</accession>
    <name>A0A0C1K052_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phrB</name>
        <name evidence="6" type="ORF">DB41_FK00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA photolyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000072">
        <property type="protein sequence ID" value="KIC76580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384241.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000072.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76580">
        <property type="protein sequence ID" value="KIC76580"/>
        <property type="gene ID" value="DB41_FK00020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.706"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="5">
        <location>
            <begin position="3"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC76580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="475" mass="55004" checksum="5F7D90E6B528942D" modified="2015-04-01" version="1">MTNSTIIWFRQDLRLEDNPALQAALQKGASILPVYIYSPEEEGDWPPGAASRWWLHHSLQSLADELLKNDLHLVIRAGNTQKILEELCQSTGSTSIFWNRRYEPAVIKRDALLKSHFHELGIETKSFNSSLLFEPWTNLNKEKKPFQVFTPFWKACQKLPDPPLPLAWEPKKKLVSVRVDSMGIDKLNLLPHIHWDRGIQATWKPGSLNAKKALMDFIKNSIYEYKDLRDRPDLPGVSRLSPYLHFGEISPRTIWHTIKEQCDPSKEGVEAYLRQLGWREFAYHLLYHFPHTSKEPLREEFNQFPWDNNPDHLKAWQKGHTGYPIVDAGIRQMWTIGWMHNRLRLIVGSFLVKDLLIAWQEGFAWFWDTLVDADLANNTLGWQWVAGCGADAAPYFRIFNPITQGEKFDPNGDFVRQWVPELAALPNEWIHKPWAAPEKTLREAGIELGVTYPKPIVDHAKAREKALAAFQEIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0F6</accession>
    <name>A0A0C1K0F6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="1 2">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 5" type="primary">murF</name>
        <name evidence="5" type="ORF">DB41_FD00090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="1 2"/>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76650">
        <property type="protein sequence ID" value="KIC76650"/>
        <property type="gene ID" value="DB41_FD00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.650"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 2" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1 2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 2" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="4">
        <location>
            <begin position="94"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="3">
        <location>
            <begin position="301"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="96"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC76650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="443" mass="48422" checksum="F44362D25E6378BD" modified="2015-04-01" version="1">MPLPKDQAVFRGVSVDSRLHRPENLFFSLPGAQTDGHHFLEKIASQGSKGAVVSRDYGGPDYGMLLIRVENPLIALQNLAQLIIKQSKARVVAVTGSVGKTTTKDFITTILKEKFKVASSPGNSNSQIGVPLAILNHTEGQEEIIVLEMGMSHPGNLKALINIAPPECAIITQVALAHACNFDSLEAIACAKAEILTHASTALAILHRDIINYSEIIKIGPCRKLSFSFDHPLADYSIAATQTDGLAVRSNEQIYKLGSFPILGKHHQANFLAAVACAEYFGMSPKEIALGMSKLVLPASRGQLIEKNGIFFINDVYNASPLSVKAALENIPSPKEGGRKIAVLADMLELGQFSKKAHEEIGEYALNQVDSMFCYGAESRLIFDCWQKYGRSAYWYNHRAELVDVLKSYLREGDVVLIKGSKGTQISKLLEEWESSPNDHIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0G1</accession>
    <name>A0A0C1K0G1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">DB41_FD00140</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kinesin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000066">
        <property type="protein sequence ID" value="KIC76655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76655">
        <property type="protein sequence ID" value="KIC76655"/>
        <property type="gene ID" value="DB41_FD00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.655"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002151">
        <property type="entry name" value="Kinesin_light"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00381">
        <property type="entry name" value="KINESINLIGHT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KIC76655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="166" mass="18636" checksum="0137762A681BEBC4" modified="2015-04-01" version="1" fragment="single">ENHPTIARDYNNLGMIYLDQGNLDKAAEYCNKALLITLKRYGKNHPTVAASYNNLGQIYQDQGNSEQAAEYTSKALAIHLKLFGKKHPTVATSYNNLGQIYKEQGNLKQALEYTKKAVTILLKLFGENHPAVATSCYNIGLIYYNQGNYKKAAEYAKKARSIKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0J8</accession>
    <name>A0A0C1K0J8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GL00170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243893.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76276">
        <property type="protein sequence ID" value="KIC76276"/>
        <property type="gene ID" value="DB41_GL00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="124" mass="14846" checksum="F6F5CA90DAD2E56A" modified="2015-04-01" version="1">MRLARQDWRCFIESGSLIRLNKDNYLIGWGTRTWLENIYDSPSPFFYFPDFFLSSPCPWFQHKFTAIVSQHELLAAMHTYPATPLPLSWKNPYLAHFENTCKELHTHFYNKKLKKLCPIYLKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K0Y6</accession>
    <name>A0A0C1K0Y6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Group 2 truncated hemoglobin YjbI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yjbI</name>
        <name evidence="2" type="ORF">DB41_GC00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000088">
        <property type="protein sequence ID" value="KIC76441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384505.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76441">
        <property type="protein sequence ID" value="KIC76441"/>
        <property type="gene ID" value="DB41_GC00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="17025" checksum="58C1D1749FFB832D" modified="2015-04-01" version="1">MEDKGNKLSVYVPPGGPPSVTPSHEIYHLMGEHNIFKMLEEFYLELDKSPIRKMFPADMKEASKKSGAFFVFLCGGPPLYQQRFGAPMMRKRHLAFPIDETARQVWLSCFHKILESADKKFNFPMQHMAGFLNFLDKFSSWMVNEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1F1</accession>
    <name>A0A0C1K1F1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_DS00160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000034">
        <property type="protein sequence ID" value="KIC76935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243791.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76935">
        <property type="protein sequence ID" value="KIC76935"/>
        <property type="gene ID" value="DB41_DS00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.389"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="247" mass="28165" checksum="BEB87028D77DFAB6" modified="2015-04-01" version="1">MWKEIPGGKEFLGQKNIQHLSLAKKGKLFKAWVERYGKDITSLKLTGIVLTFLPQEIRLLSRLQELCLNDNQIITFPAEIPQLSQLQKLYLSHNHIAFLPGEIKQLSHLQELVLVNNQLIFCPTEIGRLSQLQHLDLRNNQLSFLPAEIGQLAQLQELYLSNNQLSSLPNEIRQLLQLKVLNLSGNQLTSLPAALKGLSRLQSLYLNNNQLSFLPPEIRQLSALKKLQVKGNPLQSLSTEIKQRFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K1Z5</accession>
    <name>A0A0C1K1Z5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EY00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000061">
        <property type="protein sequence ID" value="KIC76696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76696">
        <property type="protein sequence ID" value="KIC76696"/>
        <property type="gene ID" value="DB41_EY00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="62" mass="7614" checksum="7D5A1F638046DE55" modified="2015-04-01" version="1">MYPIDKTKREEKQFFYFYLAIQKKYGMQILATSSFLESDKEKIYYEEKKGLKRNGRKIYNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K207</accession>
    <name>A0A0C1K207_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome d ubiquinol oxidase subunit 1</fullName>
            <ecNumber evidence="13">1.10.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cydA</name>
        <name evidence="13" type="ORF">DB41_DH00080</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.-" evidence="13"/>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383423.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77060">
        <property type="protein sequence ID" value="KIC77060"/>
        <property type="gene ID" value="DB41_DH00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.243"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC77060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="467" mass="52876" checksum="F1C0ED98843A691C" modified="2015-04-01" version="1">MNVEILARFQFALTIMFHYIYPPLSIGIGLILVIMEGIYIKTKNPIYLEMAKFWTKVFALTFAMGVATGIVMEFEFGTNWANYSRFVGDVFGSALAAEGVFAFFLESGFLALLLFGWNRVSPRMHYFATWMVCLGAHFSAIWIVVANSWMQTPAGFVIEGEGIKARAVITDFWAMVFNPSSMTRLFHTIIGCWLAGAFLVISLAAYYILKNRHHEFAKNSLKIGLSVALVACILQLITGDTSARIIAKYQPAKLAAIEGLYRTQKGAPLSIWGIPNSETQTLDYGFKIPYLLSFLTFRDFNAEVKGLDIIPREDWPRVSVVFQTYHLMIATWACMIMTTLLTIYLWRKGSLFQKKWMLRLLVASSFFPQIGNQAGWVTAEMGRYPWIVQGLLRISEGLSKSVVAEQVLGSIILFGIVYTLLFILFVYMLNEKFKEGPMDPAVGDVSTLYHQQYVLVQDVFTQDKEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K258</accession>
    <name>A0A0C1K258_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartokinase 2</fullName>
            <ecNumber evidence="2">2.7.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysC</name>
        <name evidence="2" type="ORF">DB41_EO00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="2"/>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76756">
        <property type="protein sequence ID" value="KIC76756"/>
        <property type="gene ID" value="DB41_EO00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.541"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="261" mass="28538" checksum="C28608E208909E1D" modified="2015-04-01" version="1">MQTLVMKFGGAAVATAEHFSYIADLIISRKKDFQRLVVVVSAMGKTTDHLIALAKQVNPDPPRREYDMLVTVGERISCSLLAMALAAKGCEALSFTGSQSGIITCSKHTEARIIDVRPTRVLPLLDSGKIVIVAGFQGVSRLGEITTLGRGGSDTTAVALGVILKASVVEFFKDVPGVYAEDPKKNPHAVFYSKLTYKQALEVVGKGGKILHPRCIELAYKNYLPLKIRSFKTYGMGENERCTIIFEDSCQPDKHLFEDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2A1</accession>
    <name>A0A0C1K2A1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CZ00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000016">
        <property type="protein sequence ID" value="KIC77125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383323.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77125">
        <property type="protein sequence ID" value="KIC77125"/>
        <property type="gene ID" value="DB41_CZ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.180"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024484">
        <property type="entry name" value="DUF2709"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10915">
        <property type="entry name" value="DUF2709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="240" mass="28124" checksum="0905BEF229B5B2E6" modified="2015-04-01" version="1">MAQTVITEEIKSELEQFLKENQSAELVTTYLFYVEKKFNLRPVLFPKDKIIYQSAEDAVKYVEQQHQLWHETEIKIGFSNLSVNEQTKKIYICPFTGKVFGDNTHPNPQDAIYDWVSKCPENTERVNGLRVKRFFISDDPEVIKSYAAKFKPKEPITKVVYSSVLSGKLFNTKEAVIKDFKQHYLKRLSLMEVQNQNRFQLEEHFLEFIQSQLVEDKIASFVEALAEFEEFSSSVAQWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2E3</accession>
    <name>A0A0C1K2E3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CV00130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383262.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77175">
        <property type="protein sequence ID" value="KIC77175"/>
        <property type="gene ID" value="DB41_CV00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="298" mass="32398" checksum="21088DC8AE2CE57A" modified="2015-04-01" version="1">MSTYLVTPFISGEYPNKVIKWTTEHLEKARESKNNKQTLIAAGVLAADTAIHAIAVPLFAIASAFRVPVQVMFSKKPWAIQLLNKTKLASPKNVAKLALRVLATAFATLATLVMSFIKPTEATRIHETLKILPKKKAAPSKNIEETAGSQEEDHVEGSEEEKQPISMKEEIAAKAYEKHKHNVEAIQDHETAEALHPASIIDKKELSTNVQKVTHKTAVEDSEKAKEEAELAMQPKVGFTEELVAKAKAKHAAAVEAVVELEEKNGKEKAVEEENAVVAAEAGIPEAPQAPAAEKIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2G9</accession>
    <name>A0A0C1K2G9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EC00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000042">
        <property type="protein sequence ID" value="KIC76861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76861">
        <property type="protein sequence ID" value="KIC76861"/>
        <property type="gene ID" value="DB41_EC00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="39" mass="4290" checksum="2C581CF868A513BE" modified="2015-04-01" version="1">MDEELIKNGVTLKVLVGQKIHCLVSDRGSTIPQIKGKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2I3</accession>
    <name>A0A0C1K2I3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 20" type="primary">pheT</name>
        <name evidence="20" type="ORF">DB41_DZ00030</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="JRXI01000040">
        <property type="protein sequence ID" value="KIC76881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76881">
        <property type="protein sequence ID" value="KIC76881"/>
        <property type="gene ID" value="DB41_DZ00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.422"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 20" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="TRNA-binding" evidence="17">
        <location>
            <begin position="68"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="19">
        <location>
            <begin position="434"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="18">
        <location>
            <begin position="736"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KIC76881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="823" mass="92386" checksum="F7EEE7FBCA747FCB" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2U8</accession>
    <name>A0A0C1K2U8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DL00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000028">
        <property type="protein sequence ID" value="KIC77031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243772.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77031">
        <property type="protein sequence ID" value="KIC77031"/>
        <property type="gene ID" value="DB41_DL00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="497" mass="56831" checksum="B4D50CE2F6973A72" modified="2015-04-01" version="1">MPNNVGFFTAIEYGQKAKTRTQSILEKVDNYFYFSGKKAQVIQGKTKNGTVRTILLRGNSSLLARVGKVASYFTIVIPLLMLIAKAILRSTHHFRLINPKKKLEKGINISEHTISKIQHLMPKILFRKDDNEIEWLSTSNNLVFKLRESPQLVFKITCSAWGVDGKGKLPIMFNGQMDRRFKNMIKAKEVCLAHELGLLVIPQAKKFTVNVQDNKYVFIAEESLDVNADESSQEHLYYTYSKELNETIRQLAIFIAKTGFNDISWRNIPLLNEAADYDGPRRVGLIDVEYMKNVVDGFKGDNRSRGLIKCATTESQIDAIIDEAYKQSGALTSEEAQTLKNQRLDELEFENKLRHFYEQNGIKTGREPIQVDINSLGLDLTEEGQATFLTVKKGKIKSKEQTLTLKKAVEDVISQINKLIQDTPEQASLRGKRYVFLNTSHPPLQQYNLLRLPTEKFTLNKEDVKKIWVRQIIQALLEKGHLFKLVIVNSQQFFIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K2V3</accession>
    <name>A0A0C1K2V3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_JC00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000160">
        <property type="protein sequence ID" value="KIC73662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244017.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000160.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73662">
        <property type="protein sequence ID" value="KIC73662"/>
        <property type="gene ID" value="DB41_JC00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1716"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC73662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="278" mass="31801" checksum="B2F03D0D5EA0195F" modified="2015-04-01" version="1">MNPCSSLTIEHLPNEILTPILKVCAAPSLYSVCTKWRHLLATEVMPTLYKQIGKMHVPHGNVYKQAFIIDRIYKLKAELPEVTKVNAIFKQIFALASSLSPSELEFKWVTEGKRYFTLNNYSSYLININQLLMWKKIPGGEEYLEQEKIKYLPLTKKGELFREWIENHGKDIKSLDLTESGLTFLPPEIGYLSQLKKLNLNNNQLTTLLVEIGHLFQLEELYLDNNQLTTLPIEIGQLSQLQTLNLGGNQLATLPAEIGQLPQLQCLYLKTTSLPLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K376</accession>
    <name>A0A0C1K376_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CT00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77191">
        <property type="protein sequence ID" value="KIC77191"/>
        <property type="gene ID" value="DB41_CT00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="87" mass="10464" checksum="5B454CEDDE7EF2AC" modified="2015-04-01" version="1">MDLTGFNKVIHSAGRKHHFSLEESIKLMLVQKFDLPSSKQRTYERQEEHGFQGMIYSLFIARWVLLPPWMRLFNNRVFLSTITYVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K5K3</accession>
    <name>A0A0C1K5K3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative metal transport system membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">DB41_IJ00330</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385948.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74562">
        <property type="protein sequence ID" value="KIC74562"/>
        <property type="gene ID" value="DB41_IJ00330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1614"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC74562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="291" mass="31344" checksum="C45AFD9E65A14EDA" modified="2015-04-01" version="1">MTSFFDALHTNPLLLAAILAGIAASFVSGIIGSYVVVKRIIFICGSISHAVLSGIGICLWLERAKGFVGVSPLLGALIAAIVSSLLIGWIHLHYRQREDTVIAAIWSIGMAVGILFISQTPGFNVELTNFLIGNILWVTPTDLKILLTLDIVIFLTVLCLHKRFLAICFDEEQAQLQGISVNSLYLLLLVLTAVSIVLLIQVVGIILVMTMLTIPAAIANLFTTRLSQMMAIAICISAGFCFFGMQAAFYMDWPGGATIALVAGLTYVLTLLGKYGIKRARKTSLAIPSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K988</accession>
    <name>A0A0C1K988_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exopolysaccharide production protein ExoY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">exoY</name>
        <name evidence="4" type="ORF">DB41_HH00150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000118">
        <property type="protein sequence ID" value="KIC75722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75722">
        <property type="protein sequence ID" value="KIC75722"/>
        <property type="gene ID" value="DB41_HH00150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1212"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="37"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="235" mass="26708" checksum="4251233EC0ABD967" modified="2015-04-01" version="1">MVGKQKIMDNSPQWMQESTTLRFSPSLGLTVKRNPTKRLFDIIFSLCVLIITLPVLAIVAVSVYFSSKGKIIYSQERIGRGGKPFRCYKFRTMYPDADARLDEILESSLELKREWANAHKLKNDPRVTPIGKFLRKTSLDEFPQFVNVLKGDLSVVGPRPVVQYEVVRHLGYKATKILSVRPGVTGLWQVSGRSDISYANRIKLDEQYIESQSLLLDIKIIAKTIPIVCFPRGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9P8</accession>
    <name>A0A0C1K9P8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Chaperone protein ClpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">clpB</name>
        <name evidence="9" type="ORF">DB41_GZ00560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000111">
        <property type="protein sequence ID" value="KIC75892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385014.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000111.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75892">
        <property type="protein sequence ID" value="KIC75892"/>
        <property type="gene ID" value="DB41_GZ00560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1122"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="8">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="412"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KIC75892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="868" mass="98154" checksum="9A4ADC7A7C385E6D" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBG1</accession>
    <name>A0A0C1KBG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GA00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000086">
        <property type="protein sequence ID" value="KIC76487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384445.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76487">
        <property type="protein sequence ID" value="KIC76487"/>
        <property type="gene ID" value="DB41_GA00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024623">
        <property type="entry name" value="YtxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12732">
        <property type="entry name" value="YtxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="200" mass="22057" checksum="D59F2D523AD4F1EF" modified="2015-04-01" version="1">MVKVKPRNKKPLTPPEPSTNEQVSNIALGAAAGCLIGAAAALFFAPKPKGHKFTRALDSMYDQVSDTAQEYAHEAMDKGHKIYDNAKDSIDHICHAASDAFSSYSTNRNIVLGIIGAGLIGASAVYALSQQSSEEEEGLVDKIKACNWLDVAKFVADKFSGKSQEEDDSEDNEEHYHPVHRMMDWAMTGLNIWQEMKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBW1</accession>
    <name>A0A0C1KBW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76592">
        <property type="protein sequence ID" value="KIC76592"/>
        <property type="gene ID" value="DB41_FI00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="91" mass="10368" checksum="BEC1CB44CAA613F3" modified="2015-04-01" version="1">MFNRISKKIIGILFAGITEEYGVCYNYEGFGEHKVKALQATPQQIKVLGKEKCQKLNKIKLPSELKIAQIAQAGREKRIKKSNQRAIETYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KBY7</accession>
    <name>A0A0C1KBY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FI00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000070">
        <property type="protein sequence ID" value="KIC76612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384177.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000070.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76612">
        <property type="protein sequence ID" value="KIC76612"/>
        <property type="gene ID" value="DB41_FI00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="168" mass="19684" checksum="A3213EFEF3A07B12" modified="2015-04-01" version="1">MLKIEIPKRAAHCMHGNEPLIPEMEFYSILLFQEEEYQRKDFCLACWEKFAKEDFSTTAKTAWKAKVVSKKEKEEISFKTRDEKAFYLLKNLLQSPSEEEWAEAFILALYLARRKIIYLRQELPQENGSVVAIYEVAATEEMWAVKRKPLSSSDIKALQVKIAEKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD70</accession>
    <name>A0A0C1KD70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyribodipyrimidine photolyase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DN00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76982">
        <property type="protein sequence ID" value="KIC76982"/>
        <property type="gene ID" value="DB41_DN00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.293"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007357">
        <property type="entry name" value="PhrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04244">
        <property type="entry name" value="DPRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_7" evidence="1">
        <location>
            <begin position="287"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="444" mass="51856" checksum="15BB6DD9B0502F08" modified="2015-04-01" version="1">MFLRAAMKAYAEWLEKQGYSVFYIDSTSLNKRGDLFEILAQKEYDQVHLANLTDDWLSQDLTEAARKNHWNLCFYESPMFLCTEKELQLFFKEKTHYSMVPFYIYQRKKLNILMEGDSPVGGKYSFDKENRERLPKGIAIPPLIVPKQNRWVKEAVEYVEKEFPNAYGKSTPFSYAVTFNEAKEVLSDFVAHRLQLFGTYEDAIHATEAVIFHSGLSPLLNIGLITPQEVVEKTLSAHTNLNIPLNSLEGFLRQIIGWREFIRACYLLKGRKERCSNFFKHTAPLPKGFWDGTTGILPIDNVIKRLLQTGYCHHIERLMILGNFLLLVETDPNAVYEWFMGYFVDAYDWVMVPNVYGMSQYADKGLMSTKPYISGANYLLKMSAYNKEEWVDKWDGLFWRFLAKHQAFFERNPRTKMLLKLLQKNANTIHPKIALAETWLMQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDP1</accession>
    <name>A0A0C1KDP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DC00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77092">
        <property type="protein sequence ID" value="KIC77092"/>
        <property type="gene ID" value="DB41_DC00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="47" mass="5391" checksum="7B83A66B029F9C9F" modified="2015-04-01" version="1">MQQEFSCPSDAKRQLDKVAKKLKYIQIIESQMLATQKHATSGWPKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KE06</accession>
    <name>A0A0C1KE06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CR00010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000008">
        <property type="protein sequence ID" value="KIC77207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243744.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77207">
        <property type="protein sequence ID" value="KIC77207"/>
        <property type="gene ID" value="DB41_CR00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="464" mass="52843" checksum="E93777952182EF97" modified="2015-04-01" version="1" fragment="single">MMPSISTSNTHPSSRLAVSENIEDAVSGRLMTRAVTLFPCGHTFNEDTVISCLARNKLCPLDSQLIERHIPNPTIRLLAGIAEADFLSEFFRERYIALLINLLNDPSIKAIPSLANLLENQSKTLMSQFGEQLTEEERINYNWTRDLLDENKKIRQFVFNRLQQTHPRAPLPVGVSLSPLSTSSPSGVPKEIGCYSHRFLPPPPISAALLYNMILRVHFPEGNGEFIEQTHIIDKIYKIDSHLSTEEKVLYIFQKLFTLASSLSPLGLEENIIENKASNLFNYSSYLLNISCLLLWHHLPGGTEYLSHPYIYTLPLKRKAELLIPWMKEYCTQLNHLILRSLNLIFLPPAIEQLSQLQRLYLHNNQLTTLPASIGQLSQLQRLYLHNNQLTSLPESIGQLSQLQRLYLYTNNLNTLPESIGQLSQLEELFVFNNRLSALPETIGQLSQLQYLFLSNNKLSTLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H164</accession>
    <name>A0A0C1H164_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BB00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000222">
        <property type="protein sequence ID" value="KIC71469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386968.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000222.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71469">
        <property type="protein sequence ID" value="KIC71469"/>
        <property type="gene ID" value="DB41_BB00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039365">
        <property type="entry name" value="IS701-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33627">
        <property type="entry name" value="PTHR33627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="218" mass="25748" checksum="2160B321DA5B974D" modified="2015-04-01" version="1">MGELDKRQLTFVAQIPENHSFWPIDIPLNSTKNIKGRPRKYPEVADRNFKPLSAKKWLKKLILQGSKWQKVKLTLQSKKCSEVMAIRAKETIPQAFYRSGVERWLIMEKLVNDQHKYYVSNASKDTSLPCMVEWIHERWKIEQGYQQMKEELGLDHFEGRSWLGLHHHLTLCFMAYSFLTLLKYQAKDKKNLNDSASSKKINQQLILHYHLPFLPSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1H5G7</accession>
    <name>A0A0C1H5G7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 4,6-dehydratase (Inverting)</fullName>
            <ecNumber evidence="3">4.2.1.115</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pseB</name>
        <name evidence="3" type="ORF">DB41_KD00140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.115" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000185">
        <property type="protein sequence ID" value="KIC72714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386297.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000185.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72714">
        <property type="protein sequence ID" value="KIC72714"/>
        <property type="gene ID" value="DB41_KD00140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1872"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020025">
        <property type="entry name" value="PseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03589">
        <property type="entry name" value="PseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysacc_synt_2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC72714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="339" mass="38297" checksum="0E626F41F5532B23" modified="2015-04-01" version="1">MHTTNFFKDKTLLITGGTGSFGQTLAKRLLIEDQCRKVIIFSRDEWKQWEMRQSAPIFSHPKIRYFLGDVRDKSRLKRAFSEVNYIVHAAALKQVPAAEYNPTEFIKTNIIGAMNVIDAAIDSGVEKVMALSTDKAANPINLYGATKLCADKLFVAGNSYVGARSHPTFAVVRYGNVLGSRGSVIPFWKKLLAEGAQALPITDKRMTRFWITLEQSVDFVLQSFLRSQGGEIFVPKIPSMKIVDLAQAFAPAIPHKYTGIREGEKLHELMIGLEDARHTLEFTDHYLIIPELYHHDESLKEKLLTRGEGRRLPEDFSYASNTNSQWLGIEALRQLILQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBF6</accession>
    <name>A0A0C1HBF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IF00110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243983.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74764">
        <property type="protein sequence ID" value="KIC74764"/>
        <property type="gene ID" value="DB41_IF00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1562"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="653" mass="74054" checksum="4A97A4860756A2D3" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HBX2</accession>
    <name>A0A0C1HBX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_IB00520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385731.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000136.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74919">
        <property type="protein sequence ID" value="KIC74919"/>
        <property type="gene ID" value="DB41_IB00520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1485"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="154" mass="18172" checksum="B85AD71C89695E45" modified="2015-04-01" version="1">MEKQCTATAYIFDNEKVLLIFHRKLSKWLPPGGHMYPHETPPMAAKREVKEETGLEVEIILQENIWIERWNAHSFERPYLCLLEEIPPFGDQPAHQHVDFIYITRPIGGEIKENPCETNGIRWFTLEEIEALNPDEEIFVETQQTLRHLFLRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HCQ9</accession>
    <name>A0A0C1HCQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HT00030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000130">
        <property type="protein sequence ID" value="KIC75199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75199">
        <property type="protein sequence ID" value="KIC75199"/>
        <property type="gene ID" value="DB41_HT00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="73" mass="8388" checksum="F50A5FFA24257A34" modified="2015-04-01" version="1">MYKTSLFLLVSAQSFSFGFLPSSVVIVFKLCQVGIWIENNQLQVQENSHLTYQKSIQFTKQASKLKISLFKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-02-10" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HFZ6</accession>
    <name>A0A0C1HFZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GK00230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000096">
        <property type="protein sequence ID" value="KIC76309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76309">
        <property type="protein sequence ID" value="KIC76309"/>
        <property type="gene ID" value="DB41_GK00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="78" mass="9468" checksum="85D57CF1182547FC" modified="2015-04-01" version="1">MLNDRVILWFKGQDVRILRVLTDRGTEYCGAREHHGYELYLAIEDMDYFRTKARHPLNKWNLRKVSPDYPERILCHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HH06</accession>
    <name>A0A0C1HH06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_FJ00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000071">
        <property type="protein sequence ID" value="KIC76589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243845.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000071.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76589">
        <property type="protein sequence ID" value="KIC76589"/>
        <property type="gene ID" value="DB41_FJ00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="79" mass="9695" checksum="5E3B6ED7A2784F8F" modified="2015-04-01" version="1">MKFDKMEKLDDERFRRLTGVEYTTFDKMVQILQQADKAKKIRSGRKYKLSLENMLLMALEYMREYRTYFYISCPSYLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHE4</accession>
    <name>A0A0C1HHE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">surE</name>
        <name evidence="7" type="ORF">DB41_ET00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="JRXI01000058">
        <property type="protein sequence ID" value="KIC76734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383940.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76734">
        <property type="protein sequence ID" value="KIC76734"/>
        <property type="gene ID" value="DB41_ET00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.556"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="8"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="264" mass="29434" checksum="78823DE37777DD95" modified="2015-04-01" version="1">MSKRPHLLITNDDGIYAPGIRHLWNALKDFADITIVAPATEQSAVGVSITVRNPLRLHQVEWAGQTQAWSLTGTPADCVKMGLKVILDRKPDLIVSGINRGSNAGRNLMYSGTVGGTIEGIIQGVPGIAFSCVDYFNTDYQKVEHYVPLLVDYVVKHPLPSGSLLNVNFPTYQHEIKGFKLTRQGKEFWAEDPLERNHPAEGHSYYWLGAKLQQFEEHEDSDISWLARGYIAAVPVHVGELTDLAHFNEAKSHFEDHLNLQAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HHJ6</accession>
    <name>A0A0C1HHJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_EJ00140</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000049">
        <property type="protein sequence ID" value="KIC76784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383864.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000049.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76784">
        <property type="protein sequence ID" value="KIC76784"/>
        <property type="gene ID" value="DB41_EJ00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC76784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="147" mass="16603" checksum="60460B82CF81317B" modified="2015-04-01" version="1">MAIDYSNLGAIYHDQGNLGQAEEYINKALAIDLRLFGEHHSTVATNYNNLGLIYKKQGNLDKAAVYINKALAIDLKLFGENHHTVVRDYNNLGQIYQDQGNLEKAAKYFKKTLEIALKLFNENHPIVTMLVNKLKTISQGGAKKFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIX5</accession>
    <name>A0A0C1HIX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TSPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cpaF</name>
        <name evidence="3" type="ORF">DB41_CP00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000006">
        <property type="protein sequence ID" value="KIC77219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383159.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77219">
        <property type="protein sequence ID" value="KIC77219"/>
        <property type="gene ID" value="DB41_CP00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041126">
        <property type="entry name" value="CPAF_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17816">
        <property type="entry name" value="PDZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002146645" description="TSPc domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="366"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="564" mass="64600" checksum="ADB3024D04484FDA" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HIZ4</accession>
    <name>A0A0C1HIZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CO00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000005">
        <property type="protein sequence ID" value="KIC77239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383096.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77239">
        <property type="protein sequence ID" value="KIC77239"/>
        <property type="gene ID" value="DB41_CO00080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.41"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025197">
        <property type="entry name" value="DUF4116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13475">
        <property type="entry name" value="DUF4116"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="137"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4116" evidence="1">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="234" mass="26406" checksum="49D17A56CA9187E2" modified="2015-04-01" version="1">MLVNSLSKACLSIDRGADYIPIVSTVTNLVDIFQKVVVLPFKQKENISKNVYYTHLDQKSFRRCLTLLIPVLGNVFVGIYDVVRNKKKKALLANVQKNGLALKDGSSTLKSDRDVVHAAVQENGLALKYASKQLQNDKKVVFAAIQENGSALKYASKQLRNDKEVVLAAVQRNHLALKYASKQLRNDREVVLAAVQRNHLALKYASEELQNHWEVVLAADDRRWLGTYRLYQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HJS7</accession>
    <name>A0A0C1HJS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lrrC1_5</name>
        <name evidence="3" type="ORF">DB41_IF00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000140">
        <property type="protein sequence ID" value="KIC74763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243982.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74763">
        <property type="protein sequence ID" value="KIC74763"/>
        <property type="gene ID" value="DB41_IF00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1561"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC74763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="357" mass="40791" checksum="CB8487E28A8197F3" modified="2015-04-01" version="1">MPSLYKKIAQLHFPRKNTTTKRTLMLAKVYQLNPGLTSTEKVYQVFKQVFTLAKFISPLEFIEKTEEKRGLTLANYSSYLLNINRLLLWKKLPGGEEYLSREEIKHLPLEKKGELLRDWIEENCKNIMALDLSKVGLTYLPSEIYQLSQLQGLELNQNKLASLPAEIGQLSQLRWLYLDQNQLTSLPAEIGQLSQLAWLNLNQNQLTSLPAEIGQLFQLQRLELNQNQLTSLPAKIRQLPRLQWLDLSQNQLTSLPGEIGQLPQLQGLNLNQNQLTSLPAEIGQLLKLQWLDLSQNQLTSLPGEIGQLPQLQGLYLNQNQLTSLPAEIGQLSQLHGLELAENPLKDIPEKIRQRFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HKP8</accession>
    <name>A0A0C1HKP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_HX00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000134">
        <property type="protein sequence ID" value="KIC75018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385528.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000134.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75018">
        <property type="protein sequence ID" value="KIC75018"/>
        <property type="gene ID" value="DB41_HX00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="128" mass="14902" checksum="F132FA4FF2CA4F6E" modified="2015-04-01" version="1">MQKGHILQFDCQQCQQQVSFSIFELDQLSHSIQCPSCHKKYVFQDETLIRQLKKFALLCRQIIDSEEILGNTVVGIDLLDKHVKIPYKLLLTRFTSSLDLLIGDQPVSIRFRIEPLKDTPLEKEIHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HNX0</accession>
    <name>A0A0C1HNX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GS00070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000104">
        <property type="protein sequence ID" value="KIC75983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75983">
        <property type="protein sequence ID" value="KIC75983"/>
        <property type="gene ID" value="DB41_GS00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1017"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC75983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="5929" checksum="967336426CD64A27" modified="2015-04-01" version="1">MRKSTKYQDWLLEKLKDPDEAVVHLNDALEESLKGDEESQQLFLIALRNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HPY8</accession>
    <name>A0A0C1HPY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_GL00090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000097">
        <property type="protein sequence ID" value="KIC76268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384734.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000097.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76268">
        <property type="protein sequence ID" value="KIC76268"/>
        <property type="gene ID" value="DB41_GL00090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.942"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC76268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="401" mass="46517" checksum="00D9E482E6E1FDB1" modified="2015-04-01" version="1">MLDKYIKINSYQKFQIALKEKEIFLDETKCIVNHGTLGERVVSRTLSKVRVGLWNTIMDFVLEIFSKAYRKAKLIIKDNLERFAYMARHPQKPCIVLFKKHLETNNLNVEEERQAYKLHRSYSKEQANAELEKLSKPIGFLGHLDRKTSSESSSDVSKDNLANNEVDNKRDDHLFNEAMREKQVANPEPSIYPQNITILTTSHKGNSSLAIFNANLADIEHEKAEVHNEASEEAGDTTLLFTPQEIDSHEFPEIQEEKMDVCQETFIFESSKASILVKQSFASEHSSLEDDAIKAKKMELNHQIDDLLKDIRHLASQLADLDEECTSQLFENQLRIEENAKLWWWAKKSIKEPLKIKEEYEEKMAKIIILKEIKEAEHANLIEQQRKLTSRQPLLFKYAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRA9</accession>
    <name>A0A0C1HRA9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rsmI</name>
        <name evidence="8" type="ORF">DB41_FC00030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000065">
        <property type="protein sequence ID" value="KIC76658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384069.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000065.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76658">
        <property type="protein sequence ID" value="KIC76658"/>
        <property type="gene ID" value="DB41_FC00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.641"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC76658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="276" mass="31457" checksum="9816C36C5608E60D" modified="2015-04-01" version="1">MLYLVATPIGHLKDITLRAIETLQACDYILCEDTRHSLILLKHYEIHKPLISFHKFNEAYKEEQVIQDLKNNKTICLISDAGTPGISDPGARLVKRCLQENLKVFSVPGACAAISAICISGLETNHFLFYGFLPRPQGALINALSEILNQPFTSICYESPERIQKVLEAIHRLDAHREVVIARELTKKFEEVVRGTAQQLIARHLEKKFKGEIVLLIAKNSGPSYEDWDHLPIEEHVYRLQQENAISLQEAIKQVATLRSIPKRQVYNKIHHPKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRG7</accession>
    <name>A0A0C1HRG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_EU00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000059">
        <property type="protein sequence ID" value="KIC76723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76723">
        <property type="protein sequence ID" value="KIC76723"/>
        <property type="gene ID" value="DB41_EU00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC76723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="49" mass="5964" checksum="D2BD842B09614A6C" modified="2015-04-01" version="1">MVKIYFSKKKLIFYSKAFETYQVMGFSFLFFSFLFFFLAGFSQKLYLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HRP9</accession>
    <name>A0A0C1HRP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">rpoA</name>
        <name evidence="13" type="ORF">DB41_EI00180</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="JRXI01000048">
        <property type="protein sequence ID" value="KIC76803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383827.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76803">
        <property type="protein sequence ID" value="KIC76803"/>
        <property type="gene ID" value="DB41_EI00180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.501"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="25"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="274"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KIC76803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="371" mass="41884" checksum="B8C7803FFC40D65A" modified="2015-04-01" version="1">MSVKYGKFEMPQKILVEEDKDNSNVARIIAEPFERGFGHTIGNSMRRMMLSSLEAPAIIALRIEGVPHEYMAIEGVIEDMTNIVLNLKGALLRKLPTDESSYSRDTRILTCVLDITQEELDKNNGQYKVTLGDIVKDGSYEVVNSGLHLFTVTKPMKRQLDLRVAIGRGYVPSERHIIYDKTADEILLDASFSPVRIVNYFVENTRVGQDTDFDRLIFEVVTDGRVTPVEAVSFASQIGVKHFDVFTKAKSHSLVFDEGLGDGDSDADEMMEKLCLRIDEIELSVRSTNCLSGANIDTIAELVSIPERKMLEFRNFGKKSLNEIKAKLHEMNLSLGMDLSRYGITHDNVKDKIKHYNEDKKGRKELAKVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSY9</accession>
    <name>A0A0C1HSY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CV00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383253.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77168">
        <property type="protein sequence ID" value="KIC77168"/>
        <property type="gene ID" value="DB41_CV00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.133"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035407">
        <property type="entry name" value="DUF5399"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17377">
        <property type="entry name" value="DUF5399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="148" mass="17437" checksum="FD5EA086D31229CB" modified="2015-04-01" version="1">MATIDKLDISVYNLYAIRTRMIEQINQQFQLDQAASIPAQLQVLDNYPKPTELDVLLGIAPLYTPWAYFFPPPRFRFMRRSPFSYRVIPSFGSYDEQALHEQKLEEVLCRTPEEKQEKETLKSCFREIEKLNNWLNFIVGRVGQFLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HSZ6</accession>
    <name>A0A0C1HSZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_CV00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000012">
        <property type="protein sequence ID" value="KIC77178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383267.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77178">
        <property type="protein sequence ID" value="KIC77178"/>
        <property type="gene ID" value="DB41_CV00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.143"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="177"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="469" mass="52879" checksum="D2AA1D69B25AA305" modified="2015-04-01" version="1">MHIVRSKFKSAAGKVYETILLRESYREGKTVKKRTVGNLSNCTPEEIAAIELALKHKGNLQALTSCSGATMQEGLSVGGVWVIYQMAKRLGIVDALGNSREGQLALWQVIARVLEQGSRLSAVRLTETYALTSVIDLQEGFNEEDLYKNLLWLCQSQASIEDRLFTKSFCKEPPHLFLYDVTSSYLEGEKNELADWGYNRDKKKGKKQIVIGLLSSADGTPVSTEVFKGNTQDTSTFHAQIKKAKERFKCEKVTFVGDRGMIKSGQIENLQEHGFYYITAMTKAQILMKRGVIEYTLFDKNLAEVKEGGIRYILKRNPVRTQEIAHSRTSKLASIEKLVAMQNAYLHAHPKAQVEVALKKIKAKIERLALKTCVTVSAQDRSLSICLNQEILAEDAKLDGCYVIKTDLACDEMSMQEVHDRYKDLARVESAFRTVKSDLEIRPVYVRSEESTRGHVFNCNVSLHDYQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1HT05</accession>
    <name>A0A0C1HT05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">DB41_CT00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000010">
        <property type="protein sequence ID" value="KIC77193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77193">
        <property type="protein sequence ID" value="KIC77193"/>
        <property type="gene ID" value="DB41_CT00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.125"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KIC77193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="150" mass="17292" checksum="76AA954D2A32FCB2" modified="2015-04-01" version="1" fragment="single">RNQVFAFRKKGELFRDWIEENCKKTTDLYLSGIGLTHLPTKIWQLSQLQYLELNNNQLTSLPPEIGQLSHLQKLDLKSNQLTSLPAEVRQLSQLRVLNLQNNQLTSLPAEIGQLSQLQELYLEGNQLTSLTPEIWRLSHPTLTVAYIRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JJ13</accession>
    <name>A0A0C1JJ13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_BJ00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000230">
        <property type="protein sequence ID" value="KIC71365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052244128.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000230.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71365">
        <property type="protein sequence ID" value="KIC71365"/>
        <property type="gene ID" value="DB41_BJ00010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2290"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="149"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC71365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="519" mass="58943" checksum="AD8E274EDB829E2A" modified="2015-04-01" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JKU6</accession>
    <name>A0A0C1JKU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_CA00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000246">
        <property type="protein sequence ID" value="KIC71186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC71186">
        <property type="protein sequence ID" value="KIC71186"/>
        <property type="gene ID" value="DB41_CA00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC71186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="113" mass="12840" checksum="ED8FBF3DB8C3327E" modified="2015-04-01" version="1" fragment="single">TTSLCEQMKFICYELMHKPEAVVSETVDSTGQTVPVYKWTQALKEEVMRKLSKNNIQSLDPLFQLAQVRQDVWDLALKLSQPAKTIEGRSHKLKPLTSTLCPEKGDSGTFERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JL74</accession>
    <name>A0A0C1JL74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_AA00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000201">
        <property type="protein sequence ID" value="KIC72035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386563.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000201.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72035">
        <property type="protein sequence ID" value="KIC72035"/>
        <property type="gene ID" value="DB41_AA00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC72035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="119" mass="13586" checksum="2135A80B569884FE" modified="2015-04-01" version="1">MNDKKAKNIFEAVKNSATSLVSKSHESGPEKKEVIPAEEVNFLKTDEILQLHGDAEINEMLNKMYRMQEDIQSKMHEMYGNAGLSTHQVRNYLDNPSNFSPEMWQKNSGAKRSAREKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JLH9</accession>
    <name>A0A0C1JLH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KU00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000199">
        <property type="protein sequence ID" value="KIC72115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72115">
        <property type="protein sequence ID" value="KIC72115"/>
        <property type="gene ID" value="DB41_KU00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="51" mass="5870" checksum="E98D2449111BF249" modified="2015-04-01" version="1">MSLVKLIKLLSSMLLMLILSTNLLAKKFSWPSIIFLKTLTIKEEGLYHMAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JNY5</accession>
    <name>A0A0C1JNY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">pyrH</name>
        <name evidence="8" type="ORF">DB41_KQ00110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="JRXI01000196">
        <property type="protein sequence ID" value="KIC72246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_042239303.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000196.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72246">
        <property type="protein sequence ID" value="KIC72246"/>
        <property type="gene ID" value="DB41_KQ00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.2015"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="136"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KIC72246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="240" mass="26090" checksum="CEB6D65004ED34D7" modified="2015-04-01" version="1">MTNLSNAKRILLKLSGETLLGEQPFGIHFPTTQQLASALKNIKQEGFELALVIGGGNLFRGLQLKDSKIPRSAADQMGMLATLMNGIALQQALTSIGCTTKLISALECPKVAESYNWNRTNDYLAAGHIVLFVGGTGNPYFTTDSAAALRACEIQADVLLKATKVKGVYTQDPLKFPQAKKYMTLSYSQYLAEKLEVMDTTSIALCMNNQLPIFVFSMEALGKESLKQILSKTENGTLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JPX1</accession>
    <name>A0A0C1JPX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperonin GroEL</fullName>
            <ecNumber evidence="3">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-60</fullName>
            <shortName evidence="3">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groL1</name>
        <name evidence="3" type="synonym">groEL</name>
        <name evidence="3" type="synonym">groL</name>
        <name evidence="6" type="ORF">DB41_KI00050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000189">
        <property type="protein sequence ID" value="KIC72561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386339.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000189.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72561">
        <property type="protein sequence ID" value="KIC72561"/>
        <property type="gene ID" value="DB41_KI00050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1897"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC72561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="563" mass="58805" checksum="1AD30B4402D257C0" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JR18</accession>
    <name>A0A0C1JR18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_JE00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000162">
        <property type="protein sequence ID" value="KIC73605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC73605">
        <property type="protein sequence ID" value="KIC73605"/>
        <property type="gene ID" value="DB41_JE00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC73605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="156" mass="17802" checksum="22CB334A5D0B8536" modified="2015-04-01" version="1" fragment="single">MVNSLHQASPNLMIQQPAESQQKIFQGFNISSDGKSAVKILRVEGKELKFTVFFPSNMQTEDRRHKYLQHFNDDQLNRLGQYALDLGLGQAKKEARGKLEAIVLNTTSSGSLNEILKKYSKLEAPKQISVEYYKERLHQLQHSDSLAQDKELQAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JT00</accession>
    <name>A0A0C1JT00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">htrA</name>
        <name evidence="6" type="ORF">DB41_IR00100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">TUME1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000149">
        <property type="protein sequence ID" value="KIC74240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386050.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000149.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="S01.480"/>
    <dbReference type="EnsemblBacteria" id="KIC74240">
        <property type="protein sequence ID" value="KIC74240"/>
        <property type="gene ID" value="DB41_IR00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1671"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="273"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="378"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KIC74240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="472" mass="50979" checksum="5726A78629F31784" modified="2015-04-01" version="1">MHLIKRSLWTLVCFSLVFSQGSLLSSKEISSNVLLQDFTQIADQAIPAVVSIQVKTKSFFPPRSNFFNEEFFQPFQPFFGAPLYPEPLPELEINQGSGFIVSSDGYIITNSHVVNKATEIEVILNDKRSFTATIIGQDPSTDVAVLKIDAQGLPYLKLANSDEIKVGQWAVAIGAPLGLEASLTVGVVSAKGRNNLDIAQIEDFIQIDAAVNRGNSGGPLLNLKSEVIGMNTAIISRNGSGHMGIGFAIPSNIIKNDFEQILESGTISNGFIGVALQIVDKDLAKALGLEKPQGALVAEVSKDSPAEKAGIKQGDVILQYNDRSFNTIGELRNAIGLMKPGSKLTLTIQRKDIPPFTLTLEVGRMPSLGERTPSSTQKENKLGLEVQELTPELSRSLGYGDQKGVVISKILPNSAAAWTGLKKGTLILSLDQQPVSSVDQFNKLLDTHDSNKPVLLLAKQGNATRFISLWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JTX4</accession>
    <name>A0A0C1JTX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rrm2</name>
        <name evidence="5" type="ORF">DB41_IJ00260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4"/>
    <dbReference type="EMBL" id="JRXI01000143">
        <property type="protein sequence ID" value="KIC74555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385940.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000143.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74555">
        <property type="protein sequence ID" value="KIC74555"/>
        <property type="gene ID" value="DB41_IJ00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1606"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC74555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="324" mass="37563" checksum="AB041AC64CE21EEB" modified="2015-04-01" version="1">MQALHEPILLENKERFVLFPINHQDIWQMYKKAEASFWTAEEIDLSTDVQHWEKKLNENERHFIKHILAFFAASDGIVNENLAVNFLNEVQYPEARCFYGFQIMIENIHSETYSLLIETYIKDSQEKSMLFHALDTLPCVAKKGEWALKWISKGGFAERLVAFAAVEGIFFSGSFCSIFWLKKRGLMPGLSFANELISRDEGLHCDFACLIYSQLAHKLSEELVKEIIGDAVKIEKEFVMEALPVKLIGMNGDLMCQYIEFVADRLLNALGYSKLYQVNNPFDFMELISLQGKTNFFEKRVSEYQKPGVMSTQRNHEFTLNEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JVP2</accession>
    <name>A0A0C1JVP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative V-type sodium ATP synthase subunit K (NtpK)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ntpK</name>
        <name evidence="7" type="ORF">DB41_HW00270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000133">
        <property type="protein sequence ID" value="KIC75115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75115">
        <property type="protein sequence ID" value="KIC75115"/>
        <property type="gene ID" value="DB41_HW00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1382"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033177">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, proton-transporting domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="6">
        <location>
            <begin position="7"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="6">
        <location>
            <begin position="82"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC75115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="140" mass="14321" checksum="B96C69AC55501B27" modified="2015-04-01" version="1">MDFSMAGPAIALGLSLIGSCIGCYIAGAASHAAMSRTEEGHGKFIGMSAAPSSQCIYGFLEMLLMSRAIQEGTLSPLSAVIIGLSAGGAIMLSAIYQGKVCATGIQATLKEPSLFGKCFAAIGIIESVSLFAFVFSLLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JWT4</accession>
    <name>A0A0C1JWT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_IB00340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000136">
        <property type="protein sequence ID" value="KIC74901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC74901">
        <property type="protein sequence ID" value="KIC74901"/>
        <property type="gene ID" value="DB41_IB00340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC74901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="60" mass="7204" checksum="F315C6AE6DC80FF4" modified="2015-04-01" version="1">MFTIFLFNSSIFFFFSSSYPFESLRLLAHAPFEKVYCLFEEFNCIIYSFAYYLNGEKHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JYT1</accession>
    <name>A0A0C1JYT1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fabG_2</name>
        <name evidence="4" type="ORF">DB41_HJ00060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="JRXI01000120">
        <property type="protein sequence ID" value="KIC75606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039385300.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000120.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75606">
        <property type="protein sequence ID" value="KIC75606"/>
        <property type="gene ID" value="DB41_HJ00060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1249"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="62"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="154"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="246" mass="26514" checksum="FC1DAEB941040CB2" modified="2015-04-01" version="1">MHHLLNNQVAIVTGGTAGIGKAIAREFARQGATVAIFGTNEKRGQEVVQEIGAEKASFYPVNVAKTLEVEAAIKQVQQNYGKVDILVNNAGIARDQLMLKMTEEDWDTVMEVNLKSCYNTCKALTRHMLKARQGVIINISSVIGLIGNSGQANYAASKAAIIGFTKALAKEFASRNIRINCIAPGFIDTQMTEAMTEQQRQAILSSIPMERMGAPEDIANAAVFLASSMAQYMTGQVLVVDGGMVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ37</accession>
    <name>A0A0C1JZ37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_KK00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000191">
        <property type="protein sequence ID" value="KIC72482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039386385.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000191.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC72482">
        <property type="protein sequence ID" value="KIC72482"/>
        <property type="gene ID" value="DB41_KK00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC72482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="718" mass="80800" checksum="579A98878433B02F" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1JZ89</accession>
    <name>A0A0C1JZ89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_GI00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000094">
        <property type="protein sequence ID" value="KIC76335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039384640.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76335">
        <property type="protein sequence ID" value="KIC76335"/>
        <property type="gene ID" value="DB41_GI00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="92" mass="10123" checksum="5B3B9A02DEA3D129" modified="2015-04-01" version="1">MIPSSSTSSPLTIFCTSVPENIEDAVSGELMTRAVTLFPCGHTFNEDTVIQCLARNKLCPLDRMPVEKHAPNHTVRQLAEKAKSHPLVIRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K120</accession>
    <name>A0A0C1K120_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EG00050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000046">
        <property type="protein sequence ID" value="KIC76840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383763.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000046.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76840">
        <property type="protein sequence ID" value="KIC76840"/>
        <property type="gene ID" value="DB41_EG00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="135" mass="15058" checksum="E4066BEEB51936AB" modified="2015-04-01" version="1">MNLPDTFTVTNKSLKPFRNDFGKKIPSTYKQANWKGRLYCCIQLACSPLTIPLKIVSRVNQIAGLATVLMLAIIKRAEQTLKRKHTAKNWDGERKVVLALTDCLLALALCPITIGASRIRYFVGIINPAKAFPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K317</accession>
    <name>A0A0C1K317_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DC00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000019">
        <property type="protein sequence ID" value="KIC77091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383381.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77091">
        <property type="protein sequence ID" value="KIC77091"/>
        <property type="gene ID" value="DB41_DC00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC77091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="77" mass="8825" checksum="1D0509E2F8511228" modified="2015-04-01" version="1">MLDYIVGDSSLYTPAALQVFKIEQSLFATHVPMQIKEAKELLFEAPYDKTVEIVEGYRAFKTTSCYAGVEQRWVVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K711</accession>
    <name>A0A0C1K711_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">DB41_HY00380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000135">
        <property type="protein sequence ID" value="KIC75012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243967.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000135.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75012">
        <property type="protein sequence ID" value="KIC75012"/>
        <property type="gene ID" value="DB41_HY00380"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1431"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018024">
        <property type="term" value="F:histone-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021180">
        <property type="entry name" value="Protein_Lys_MeTrfase_predicted"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="PTHR13610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029047">
        <property type="entry name" value="Protein_Lys_MeTrfase_predicted"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51569">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KIC75012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="233" mass="27282" checksum="413FF616AE97D38C" modified="2015-04-01" version="1">MSKIEGKDVKEYLTLLSVNLVVKVKNLREYVKVIYRYYRKLSYAVVDSSLLLMYLFDNPFTVSRRYFSCRSDSEEYIYGETPLTTLEKISKEARIQSQDLVIELGCGRGRTCFWLQKFTGCRVVGLDMVPDFILRAKRIQHKLKITHLEFKQENFLLADLTKASVIYLYGTCLEDQTIKRLIEQLKQLAPGTRIITVSYPLTDYTEEPTFEIMKRFSAPFTWGKADVYIQIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9C6</accession>
    <name>A0A0C1K9C6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase of ISBst12-like element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">DB41_HF00010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000116">
        <property type="protein sequence ID" value="KIC75772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75772">
        <property type="protein sequence ID" value="KIC75772"/>
        <property type="gene ID" value="DB41_HF00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024474">
        <property type="entry name" value="Znf_dom_IS66"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13005">
        <property type="entry name" value="zf-IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="3">
        <location>
            <begin position="18"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="zf-IS66" evidence="2">
        <location>
            <begin position="100"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KIC75772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="144" mass="16345" checksum="248FD9D690B3C24F" modified="2015-04-01" version="1" fragment="single">MQPSYEQLFTENAELRAENAQLKAMVNRLEKVITKLEARMAQLEEQLNQDSKNSSKPPSTDQKANRSLLTKAENRPYHPGASRYLLPASAVTSHEARCLKACPHCYSAMHATDKIFSWQQIELPEIKPLVHQIDLVTSRCPCCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1K9Z8</accession>
    <name>A0A0C1K9Z8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0135 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_GU00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000106">
        <property type="protein sequence ID" value="KIC75962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_052243911.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC75962">
        <property type="protein sequence ID" value="KIC75962"/>
        <property type="gene ID" value="DB41_GU00110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.1031"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC75962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="251" mass="28341" checksum="19F4D955E12D0C08" modified="2015-04-01" version="1">MITLQELCVYLDKLLEPSSIKDYGLNGLQVEGKKEILKLATAVSANLETLQAAVHWNADALLVHHGLFWNQDSYQIRGIKKAKLALLCQHNLSLIAYHLPLDIHCEWGNNWRAALEMGWDNLQPFGLANGLYLGVKGRLKKMSRLDFQKKLEDYYAHVAHIAPGGKEEIETVGLVSGGGYKFLSYAADEKLDAFISGNFDEPAWSQAYEEKINFFAMGHSATEKIGPRALATHLHEKFQMECRFIDIYNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCD5</accession>
    <name>A0A0C1KCD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_EO00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000054">
        <property type="protein sequence ID" value="KIC76757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383896.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000054.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76757">
        <property type="protein sequence ID" value="KIC76757"/>
        <property type="gene ID" value="DB41_EO00100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.542"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="641" mass="75279" checksum="7646F3E91B35E040" modified="2015-04-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KCM5</accession>
    <name>A0A0C1KCM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplB</name>
        <name evidence="7" type="ORF">DB41_EH00160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">TUME1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000047">
        <property type="protein sequence ID" value="KIC76832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_039383795.1">
        <property type="nucleotide sequence ID" value="NZ_JRXI01000047.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76832">
        <property type="protein sequence ID" value="KIC76832"/>
        <property type="gene ID" value="DB41_EH00160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1478174.3.peg.481"/>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="131"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KIC76832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="281" mass="31392" checksum="07FD22C787F4E6D1" modified="2015-04-01" version="1">MLKKYRPITAGTRQLILPINETLTRAKEGSRAKVKPTKSLMLPKKRTNGRNNNGHITCRHKGGGHKRHYRIIDFKRDKENIPARVASIEYDPNRSAYIALLNYSDGEKRYILAPHGLKDGDVVQTSDEPPFSVGCCMKLKFMPLGSTIHAIEMIPGRGAKMVRSAGLSAQLMARSGGYATIRMPSGEVRMVSENCRAAFGMVSNSEHNLRVEGKAGRMRWKGIRPTVRGTAMNPVDHPHGGGEGKHKGNIPQTPWALYTRGLRTRSQKKSNKFIVKDRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KD79</accession>
    <name>A0A0C1KD79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">DB41_DN00080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000030">
        <property type="protein sequence ID" value="KIC76987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC76987">
        <property type="protein sequence ID" value="KIC76987"/>
        <property type="gene ID" value="DB41_DN00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KIC76987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="56" mass="6410" checksum="68EABFD4474956CD" modified="2015-04-01" version="1">MTKEMNDPLKVIKDFGRDEEARQLWKRLCSYYGRSLAATAMSCFKEALKGILPLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-04-01" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0C1KDH2</accession>
    <name>A0A0C1KDH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">DB41_DH00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Neochlamydia sp. TUME1</name>
        <dbReference type="NCBI Taxonomy" id="1478174"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chlamydiae</taxon>
            <taxon>Parachlamydiales</taxon>
            <taxon>Parachlamydiaceae</taxon>
            <taxon>Neochlamydia</taxon>
            <taxon>unclassified Neochlamydia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2014" name="Mol. Biol. Evol." volume="31" first="2890" last="2904">
            <title>Massive expansion of Ubiquitination-related gene families within the Chlamydiae.</title>
            <authorList>
                <person name="Domman D."/>
                <person name="Collingro A."/>
                <person name="Lagkouvardos I."/>
                <person name="Gehre L."/>
                <person name="Weinmaier T."/>
                <person name="Rattei T."/>
                <person name="Subtil A."/>
                <person name="Horn M."/>
            </authorList>
            <dbReference type="PubMed" id="25069652"/>
            <dbReference type="DOI" id="10.1093/molbev/msu227"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">TUME1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JRXI01000024">
        <property type="protein sequence ID" value="KIC77057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KIC77057">
        <property type="protein sequence ID" value="KIC77057"/>
        <property type="gene ID" value="DB41_DH00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000031320">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KIC77057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000031320"/>
        </source>
    </evidence>
    <sequence length="110" mass="12422" checksum="5E9E6BD5A5779619" modified="2015-04-01" version="1">METLIYKIFLENWQRKIVAVALAVILWLCVNYSITATKTILGVPIRIINLPADKTIQGLLPNGILNKRIALTLSGRKNVIRELEPGDLEVLIDSSSIDRDEWVLLITKKI</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>